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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-23b-3p AARS2 -0.07 0.62059 0.57 0 miRNAWalker2 validate -0.14 0.00043 NA
2 hsa-miR-23b-3p ABCC1 -0.07 0.62059 0.06 0.69524 miRNAWalker2 validate -0.11 0.04726 NA
3 hsa-miR-23b-3p ABCF1 -0.07 0.62059 0.36 0.0011 miRNAWalker2 validate -0.1 0.00533 NA
4 hsa-miR-23b-3p ACER3 -0.07 0.62059 -0.77 0 MirTarget -0.1 0.0231 NA
5 hsa-miR-23b-3p ADAM19 -0.07 0.62059 0.67 0.00694 miRNATAP -0.18 0.03294 NA
6 hsa-miR-23b-3p ALDOA -0.07 0.62059 0.98 0 miRNAWalker2 validate -0.14 0.01064 NA
7 hsa-miR-23b-3p APAF1 -0.07 0.62059 0.05 0.6283 miRNATAP -0.11 0.00216 NA
8 hsa-miR-23b-3p ARHGAP11A -0.07 0.62059 1.77 0 mirMAP -0.52 0 NA
9 hsa-miR-23b-3p ASAP1 -0.07 0.62059 -0.4 0.01675 MirTarget -0.17 0.00156 NA
10 hsa-miR-23b-3p ATP2A2 -0.07 0.62059 0.63 1.0E-5 mirMAP -0.11 0.0214 NA
11 hsa-miR-23b-3p ATXN7L3 -0.07 0.62059 0.56 0 miRNATAP -0.15 0 NA
12 hsa-miR-23b-3p B3GNT5 -0.07 0.62059 -0.33 0.14374 MirTarget -0.26 0.00048 NA
13 hsa-miR-23b-3p BEND6 -0.07 0.62059 1.02 0.00304 MirTarget -0.23 0.04055 NA
14 hsa-miR-23b-3p BRI3BP -0.07 0.62059 1.17 0 mirMAP -0.27 3.0E-5 NA
15 hsa-miR-23b-3p C18orf54 -0.07 0.62059 0.22 0.30993 mirMAP -0.39 0 NA
16 hsa-miR-23b-3p C2orf69 -0.07 0.62059 0.02 0.84048 miRNATAP -0.11 0.00278 NA
17 hsa-miR-23b-3p CALU -0.07 0.62059 0.7 3.0E-5 mirMAP -0.11 0.04796 NA
18 hsa-miR-23b-3p CCDC34 -0.07 0.62059 1.46 0 MirTarget -0.26 0.00035 NA
19 hsa-miR-23b-3p CCL7 -0.07 0.62059 2.12 4.0E-5 MirTarget; miRNATAP -0.46 0.00666 NA
20 hsa-miR-23b-3p CCM2 -0.07 0.62059 0.69 2.0E-5 MirTarget -0.12 0.02546 NA
21 hsa-miR-23b-3p CCNB2 -0.07 0.62059 3.05 0 miRNAWalker2 validate -0.6 0 NA
22 hsa-miR-23b-3p CCT7 -0.07 0.62059 0.44 2.0E-5 miRNAWalker2 validate -0.16 0 NA
23 hsa-miR-23b-3p CDC20 -0.07 0.62059 3.63 0 miRNAWalker2 validate -0.66 0 NA
24 hsa-miR-23b-3p CDCA8 -0.07 0.62059 2.88 0 miRNAWalker2 validate -0.53 0 NA
25 hsa-miR-23b-3p CDK2 -0.07 0.62059 0.34 0.01969 miRNAWalker2 validate -0.32 0 NA
26 hsa-miR-23b-3p CDK5R1 -0.07 0.62059 1.4 0 mirMAP; miRNATAP -0.29 0.00058 NA
27 hsa-miR-23b-3p CDK6 -0.07 0.62059 -0.63 0.01747 mirMAP -0.24 0.00674 NA
28 hsa-miR-23b-3p CENPP -0.07 0.62059 0.51 0.00813 mirMAP -0.19 0.00251 NA
29 hsa-miR-23b-3p CFL2 -0.07 0.62059 -1.5 0 MirTarget -0.16 0.01289 NA
30 hsa-miR-23b-3p CHML -0.07 0.62059 1.06 4.0E-5 mirMAP -0.21 0.01334 NA
31 hsa-miR-23b-3p CHST11 -0.07 0.62059 -0.57 0.00975 MirTarget -0.27 0.00015 NA
32 hsa-miR-23b-3p CNTLN -0.07 0.62059 -0.91 0.00013 MirTarget -0.19 0.01711 NA
33 hsa-miR-23b-3p CREG2 -0.07 0.62059 0.94 0.05275 MirTarget -0.35 0.02794 NA
34 hsa-miR-23b-3p DCBLD2 -0.07 0.62059 0.33 0.24787 MirTarget; miRNATAP -0.22 0.01958 NA
35 hsa-miR-23b-3p DCUN1D5 -0.07 0.62059 0.75 0 MirTarget -0.17 0.00025 NA
36 hsa-miR-23b-3p DDX27 -0.07 0.62059 0.66 0 miRNAWalker2 validate -0.12 0.00142 NA
37 hsa-miR-23b-3p DDX47 -0.07 0.62059 0.2 0.08605 miRNAWalker2 validate; MirTarget -0.16 5.0E-5 NA
38 hsa-miR-23b-3p DEPDC1 -0.07 0.62059 3.45 0 MirTarget -0.72 0 NA
39 hsa-miR-23b-3p DHX33 -0.07 0.62059 0.21 0.19056 miRNAWalker2 validate -0.12 0.02542 NA
40 hsa-miR-23b-3p DHX57 -0.07 0.62059 0.41 8.0E-5 miRNAWalker2 validate -0.12 0.00033 NA
41 hsa-miR-23b-3p DIP2B -0.07 0.62059 0.05 0.73603 mirMAP -0.14 0.00175 NA
42 hsa-miR-23b-3p DNAJC6 -0.07 0.62059 -0.2 0.54776 miRNATAP -0.36 0.0007 NA
43 hsa-miR-23b-3p DONSON -0.07 0.62059 1.67 0 miRNAWalker2 validate -0.32 0 NA
44 hsa-miR-23b-3p DRP2 -0.07 0.62059 2.45 0 mirMAP -0.45 0.00124 NA
45 hsa-miR-23b-3p DUSP5 -0.07 0.62059 0.4 0.11511 MirTarget; miRNATAP -0.19 0.02688 NA
46 hsa-miR-23b-3p E2F1 -0.07 0.62059 1.31 0 miRNAWalker2 validate -0.55 0 NA
47 hsa-miR-23b-3p E2F4 -0.07 0.62059 0.24 0.01381 miRNAWalker2 validate -0.14 1.0E-5 NA
48 hsa-miR-23b-3p EIF2AK2 -0.07 0.62059 0.62 9.0E-5 mirMAP -0.22 2.0E-5 NA
49 hsa-miR-23b-3p EIF4A1 -0.07 0.62059 0.22 0.05712 miRNAWalker2 validate -0.13 0.00069 NA
50 hsa-miR-23b-3p ELOVL6 -0.07 0.62059 0.82 0.02787 MirTarget; miRNATAP -0.38 0.00213 NA
51 hsa-miR-23b-3p FAM122B -0.07 0.62059 0.56 0 mirMAP -0.23 0 NA
52 hsa-miR-23b-3p FASTKD3 -0.07 0.62059 0.94 0 MirTarget -0.1 0.04115 NA
53 hsa-miR-23b-3p FBN2 -0.07 0.62059 0.3 0.5174 MirTarget; miRNATAP -0.35 0.01918 NA
54 hsa-miR-23b-3p FBXO10 -0.07 0.62059 -0.34 0.01855 miRNATAP -0.19 7.0E-5 NA
55 hsa-miR-23b-3p FBXO22 -0.07 0.62059 0.39 0.00092 mirMAP -0.11 0.00599 NA
56 hsa-miR-23b-3p FIGN -0.07 0.62059 -0.61 0.05859 mirMAP -0.27 0.01172 NA
57 hsa-miR-23b-3p FRMD5 -0.07 0.62059 3.4 0 MirTarget -0.46 0.00093 NA
58 hsa-miR-23b-3p G2E3 -0.07 0.62059 0.56 0.00104 MirTarget -0.15 0.00975 NA
59 hsa-miR-23b-3p G3BP1 -0.07 0.62059 0.26 0.03626 miRNAWalker2 validate -0.12 0.00268 NA
60 hsa-miR-23b-3p GAPDH -0.07 0.62059 1.42 0 miRNAWalker2 validate -0.25 0.0001 NA
61 hsa-miR-23b-3p GNG4 -0.07 0.62059 1.72 0.00588 mirMAP -0.42 0.04264 NA
62 hsa-miR-23b-3p GNPDA1 -0.07 0.62059 0.26 0.03071 MirTarget; miRNATAP -0.14 0.00038 NA
63 hsa-miR-23b-3p GPC6 -0.07 0.62059 0.12 0.74393 MirTarget -0.26 0.0338 NA
64 hsa-miR-23b-3p GPR180 -0.07 0.62059 0.52 0.00037 MirTarget -0.12 0.0171 NA
65 hsa-miR-23b-3p GREB1L -0.07 0.62059 2.54 0 mirMAP -0.51 0.00419 NA
66 hsa-miR-23b-3p GXYLT1 -0.07 0.62059 -0.11 0.37942 miRNATAP -0.2 0 NA
67 hsa-miR-23b-3p HMGB2 -0.07 0.62059 0.69 0.00019 MirTarget -0.33 0 25996293 miR 23b 3p regulates the chemoresistance of gastric cancer cells by targeting ATG12 and HMGB2; Reporter gene assay and western blot analysis showed that ATG12 and HMGB2 were the direct targets of miR-23b-3p; In conclusion our data demonstrated that miR-23b-3p inhibited autophagy mediated by ATG12 and HMGB2 and sensitized GC cells to chemotherapy and suggested the potential application of miR-23b-3p in drug resistance prediction and treatment
68 hsa-miR-23b-3p HMGN2 -0.07 0.62059 0.03 0.83262 MirTarget -0.13 0.00079 NA
69 hsa-miR-23b-3p HOXA1 -0.07 0.62059 0.8 0.05685 miRNATAP -0.42 0.00249 NA
70 hsa-miR-23b-3p HS2ST1 -0.07 0.62059 0.16 0.27392 mirMAP -0.14 0.00342 NA
71 hsa-miR-23b-3p HTR2C -0.07 0.62059 0.77 0.22993 MirTarget; mirMAP; miRNATAP -0.79 0.00019 NA
72 hsa-miR-23b-3p IPO8 -0.07 0.62059 -0.17 0.13855 MirTarget; miRNATAP -0.15 0.00013 NA
73 hsa-miR-23b-3p KDM1A -0.07 0.62059 0.55 0 miRNAWalker2 validate -0.11 0.00539 NA
74 hsa-miR-23b-3p KPNA1 -0.07 0.62059 0.08 0.4478 MirTarget; miRNATAP -0.13 7.0E-5 NA
75 hsa-miR-23b-3p KPNA4 -0.07 0.62059 -0.01 0.93016 MirTarget; miRNATAP -0.11 0.0043 NA
76 hsa-miR-23b-3p KPNB1 -0.07 0.62059 0.67 0 mirMAP -0.22 0 NA
77 hsa-miR-23b-3p LBR -0.07 0.62059 0.52 8.0E-5 miRNAWalker2 validate; MirTarget; miRNATAP -0.14 0.00108 NA
78 hsa-miR-23b-3p LIN28B -0.07 0.62059 1.45 0.02672 mirMAP; miRNATAP -0.68 0.00174 NA
79 hsa-miR-23b-3p LIN54 -0.07 0.62059 0.3 0.0019 MirTarget; miRNATAP -0.11 0.00064 NA
80 hsa-miR-23b-3p LRRC40 -0.07 0.62059 0.14 0.26738 MirTarget -0.1 0.01418 NA
81 hsa-miR-23b-3p LTV1 -0.07 0.62059 -0 0.98617 MirTarget -0.13 0.00049 NA
82 hsa-miR-23b-3p MAGOHB -0.07 0.62059 0.78 0 MirTarget; miRNATAP -0.22 1.0E-5 NA
83 hsa-miR-23b-3p MAPRE1 -0.07 0.62059 0.07 0.49172 MirTarget; miRNATAP -0.13 2.0E-5 NA
84 hsa-miR-23b-3p MCFD2 -0.07 0.62059 -0.18 0.11095 miRNAWalker2 validate; MirTarget; miRNATAP -0.13 0.00056 NA
85 hsa-miR-23b-3p MCM4 -0.07 0.62059 1.8 0 MirTarget -0.39 0 NA
86 hsa-miR-23b-3p METTL2B -0.07 0.62059 0.52 8.0E-5 mirMAP -0.13 0.00254 NA
87 hsa-miR-23b-3p MRPL17 -0.07 0.62059 0.77 0 miRNATAP -0.12 0.00552 NA
88 hsa-miR-23b-3p MSH6 -0.07 0.62059 0.6 2.0E-5 miRNAWalker2 validate -0.17 0.00037 NA
89 hsa-miR-23b-3p MT2A -0.07 0.62059 -1.12 0.00025 MirTarget -0.25 0.01296 NA
90 hsa-miR-23b-3p NAA15 -0.07 0.62059 0.43 0.00049 MirTarget; mirMAP; miRNATAP -0.14 0.00051 NA
91 hsa-miR-23b-3p NAA50 -0.07 0.62059 0.32 0.01245 MirTarget; mirMAP; miRNATAP -0.16 0.00016 NA
92 hsa-miR-23b-3p NACC1 -0.07 0.62059 0.65 0 miRNATAP -0.17 0.00029 NA
93 hsa-miR-23b-3p NCOA3 -0.07 0.62059 0.14 0.24146 mirMAP -0.1 0.01071 NA
94 hsa-miR-23b-3p NLK -0.07 0.62059 0.2 0.05358 MirTarget -0.11 0.00087 NA
95 hsa-miR-23b-3p NLN -0.07 0.62059 1.36 0 mirMAP -0.14 0.02263 NA
96 hsa-miR-23b-3p NPM1 -0.07 0.62059 0.5 0.00062 miRNAWalker2 validate -0.12 0.01262 NA
97 hsa-miR-23b-3p NUP43 -0.07 0.62059 0.68 0 MirTarget -0.13 0.00016 NA
98 hsa-miR-23b-3p NUP50 -0.07 0.62059 0.26 0.01203 miRNATAP -0.12 0.00037 NA
99 hsa-miR-23b-3p OLA1 -0.07 0.62059 0.82 0 MirTarget -0.11 0.01268 NA
100 hsa-miR-23b-3p OTUB2 -0.07 0.62059 0.95 0 miRNATAP -0.13 0.04711 NA
101 hsa-miR-23b-3p PAK2 -0.07 0.62059 -0.16 0.15365 MirTarget -0.1 0.00817 NA
102 hsa-miR-23b-3p PDIA6 -0.07 0.62059 0.88 0 MirTarget -0.15 0.00146 NA
103 hsa-miR-23b-3p PEG10 -0.07 0.62059 -1.59 0.0041 mirMAP -0.43 0.01909 NA
104 hsa-miR-23b-3p PFKFB4 -0.07 0.62059 0.49 0.04491 miRNATAP -0.37 0 NA
105 hsa-miR-23b-3p PHF19 -0.07 0.62059 0.36 0.02231 miRNATAP -0.22 2.0E-5 NA
106 hsa-miR-23b-3p PITPNC1 -0.07 0.62059 0.36 0.14945 MirTarget -0.16 0.04781 NA
107 hsa-miR-23b-3p PNMA1 -0.07 0.62059 0.11 0.47275 MirTarget -0.1 0.04159 NA
108 hsa-miR-23b-3p PPAT -0.07 0.62059 1.81 0 MirTarget -0.24 0.00021 NA
109 hsa-miR-23b-3p PPIF -0.07 0.62059 1.05 0 MirTarget; miRNATAP -0.24 0 NA
110 hsa-miR-23b-3p PRAP1 -0.07 0.62059 2.15 0.00291 miRNAWalker2 validate; miRTarBase -0.49 0.04045 NA
111 hsa-miR-23b-3p PRMT6 -0.07 0.62059 0.03 0.90686 MirTarget -0.17 0.01727 NA
112 hsa-miR-23b-3p PRTFDC1 -0.07 0.62059 0.88 0.00032 MirTarget -0.26 0.00135 NA
113 hsa-miR-23b-3p PSMD14 -0.07 0.62059 0.71 0 miRNAWalker2 validate -0.16 0.00059 NA
114 hsa-miR-23b-3p RAD51 -0.07 0.62059 2.21 0 miRNAWalker2 validate -0.55 0 NA
115 hsa-miR-23b-3p RAD51AP1 -0.07 0.62059 1.97 0 MirTarget -0.57 0 NA
116 hsa-miR-23b-3p RBM17 -0.07 0.62059 0.04 0.68789 mirMAP -0.13 4.0E-5 NA
117 hsa-miR-23b-3p RCN1 -0.07 0.62059 0.69 3.0E-5 MirTarget; miRNATAP -0.12 0.02497 NA
118 hsa-miR-23b-3p RFX6 -0.07 0.62059 0.57 0.312 MirTarget; miRNATAP -0.4 0.02948 NA
119 hsa-miR-23b-3p RPN2 -0.07 0.62059 0.6 0 miRNAWalker2 validate -0.12 0.00397 NA
120 hsa-miR-23b-3p RRAGD -0.07 0.62059 -0.88 0.00022 miRNAWalker2 validate -0.17 0.02925 NA
121 hsa-miR-23b-3p RSAD2 -0.07 0.62059 -0.73 0.01086 mirMAP -0.2 0.03177 NA
122 hsa-miR-23b-3p SAMD8 -0.07 0.62059 -0.2 0.17739 MirTarget -0.11 0.01957 NA
123 hsa-miR-23b-3p SBNO1 -0.07 0.62059 0.22 0.25959 MirTarget; miRNATAP -0.13 0.04923 NA
124 hsa-miR-23b-3p SEC23A -0.07 0.62059 0.33 0.05235 MirTarget; miRNATAP -0.12 0.03812 NA
125 hsa-miR-23b-3p SEH1L -0.07 0.62059 0.37 0.00603 MirTarget -0.1 0.02395 NA
126 hsa-miR-23b-3p SEMA4B -0.07 0.62059 1.41 0 MirTarget -0.16 0.033 NA
127 hsa-miR-23b-3p SENP1 -0.07 0.62059 0.31 0.0071 mirMAP -0.19 0 NA
128 hsa-miR-23b-3p SESN2 -0.07 0.62059 0.03 0.81858 miRNATAP -0.11 0.02474 NA
129 hsa-miR-23b-3p SFXN1 -0.07 0.62059 1.45 0 mirMAP -0.2 0.00014 NA
130 hsa-miR-23b-3p SFXN5 -0.07 0.62059 0.36 0.01523 MirTarget -0.28 0 NA
131 hsa-miR-23b-3p SLC16A1 -0.07 0.62059 -0.04 0.91108 miRNAWalker2 validate -0.42 0.00029 NA
132 hsa-miR-23b-3p SLC6A15 -0.07 0.62059 0.41 0.53598 miRNAWalker2 validate -0.71 0.00116 NA
133 hsa-miR-23b-3p SLC7A1 -0.07 0.62059 0.5 0.00841 MirTarget; miRNATAP -0.15 0.01561 NA
134 hsa-miR-23b-3p SMS -0.07 0.62059 0.65 1.0E-5 MirTarget; miRNATAP -0.24 0 NA
135 hsa-miR-23b-3p SNRPC -0.07 0.62059 0.73 0 miRNAWalker2 validate -0.14 0.00081 NA
136 hsa-miR-23b-3p SRC -0.07 0.62059 0.54 0.00018 miRNAWalker2 validate; miRTarBase -0.12 0.01384 23074286 miR 23b represses proto oncogene Src kinase and functions as methylation silenced tumor suppressor with diagnostic and prognostic significance in prostate cancer; We showed that proto-oncogene Src kinase and Akt are direct targets of miR-23b; Depletion of Src by RNA interference conferred similar functional effects as that of miR-23b reconstitution; miR-23b expression caused a dramatic decrease in tumor growth in nude mice and attenuated Src expression in excised tumors compared with a control miR
137 hsa-miR-23b-3p SRPK2 -0.07 0.62059 0.28 0.01561 MirTarget -0.1 0.00684 NA
138 hsa-miR-23b-3p SSR3 -0.07 0.62059 0.36 0.00918 MirTarget -0.18 7.0E-5 NA
139 hsa-miR-23b-3p SSRP1 -0.07 0.62059 0.47 2.0E-5 miRNAWalker2 validate -0.13 0.00031 NA
140 hsa-miR-23b-3p STK11IP -0.07 0.62059 -0.02 0.90395 miRNAWalker2 validate -0.11 0.01447 NA
141 hsa-miR-23b-3p STX16 -0.07 0.62059 0.66 0 mirMAP -0.11 0.02713 NA
142 hsa-miR-23b-3p SUPT7L -0.07 0.62059 0.4 0 miRNAWalker2 validate -0.12 4.0E-5 NA
143 hsa-miR-23b-3p TCP1 -0.07 0.62059 0.22 0.0697 miRNAWalker2 validate -0.13 0.00079 NA
144 hsa-miR-23b-3p TFAM -0.07 0.62059 0.5 0.00027 MirTarget; miRNATAP -0.14 0.00267 NA
145 hsa-miR-23b-3p TFDP2 -0.07 0.62059 0.52 0.00111 mirMAP -0.15 0.0054 NA
146 hsa-miR-23b-3p TMEM120B -0.07 0.62059 0.22 0.14422 mirMAP; miRNATAP -0.14 0.00448 NA
147 hsa-miR-23b-3p TMEM38B -0.07 0.62059 -0.06 0.75952 MirTarget; mirMAP -0.25 0.00041 NA
148 hsa-miR-23b-3p TMPO -0.07 0.62059 0.53 0.00157 miRNATAP -0.31 0 NA
149 hsa-miR-23b-3p TOP1 -0.07 0.62059 0.41 0.00206 miRNATAP -0.11 0.00985 NA
150 hsa-miR-23b-3p TPM3 -0.07 0.62059 0.17 0.09795 miRNATAP -0.11 0.00068 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 MULTI ORGANISM TRANSPORT 8 68 8.384e-08 0.0001951
2 MULTI ORGANISM LOCALIZATION 8 68 8.384e-08 0.0001951
3 PEPTIDYL AMINO ACID MODIFICATION 22 841 1.527e-06 0.002368
4 SISTER CHROMATID COHESION 8 111 3.717e-06 0.004323
5 MITOTIC CELL CYCLE 20 766 4.898e-06 0.004558
6 CHROMOSOME ORGANIZATION 23 1009 8.562e-06 0.004666
7 REGULATION OF DNA RECOMBINATION 6 58 7.891e-06 0.004666
8 CELL CYCLE 27 1316 9.026e-06 0.004666
9 CELL CYCLE PROCESS 24 1081 8.31e-06 0.004666
10 REGULATION OF DOUBLE STRAND BREAK REPAIR VIA HOMOLOGOUS RECOMBINATION 4 19 1.535e-05 0.006491
11 SISTER CHROMATID SEGREGATION 9 176 1.517e-05 0.006491
12 REGULATION OF DNA METABOLIC PROCESS 12 340 2.495e-05 0.009673
NumGOOverlapSizeP ValueAdj. P Value
1 POLY A RNA BINDING 28 1170 2.955e-07 0.0002745
2 RNA BINDING 33 1598 6.488e-07 0.0003013
3 ATPASE ACTIVITY 15 427 2.487e-06 0.00077
4 PURINE NTP DEPENDENT HELICASE ACTIVITY 7 98 1.622e-05 0.00243
5 ATPASE ACTIVITY COUPLED 12 313 1.099e-05 0.00243
6 RNA HELICASE ACTIVITY 6 67 1.831e-05 0.00243
7 ADENYL NUCLEOTIDE BINDING 29 1514 1.483e-05 0.00243
NumGOOverlapSizeP ValueAdj. P Value
1 NUCLEAR ENVELOPE 15 416 1.805e-06 0.001054
2 ENVELOPE 24 1090 9.542e-06 0.002786
3 NUCLEAR PORE 6 77 4.066e-05 0.007915

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Cell_cycle_hsa04110 8 124 8.47e-06 0.0004404
2 p53_signaling_pathway_hsa04115 5 68 0.0002396 0.006231
3 Cellular_senescence_hsa04218 6 160 0.002082 0.03609
4 Adherens_junction_hsa04520 3 72 0.02138 0.2779
5 Oocyte_meiosis_hsa04114 3 124 0.08208 0.7393
6 FoxO_signaling_pathway_hsa04068 3 132 0.0947 0.7393
7 Mitophagy_animal_hsa04137 2 65 0.09952 0.7393
8 mTOR_signaling_pathway_hsa04150 3 151 0.1275 0.8291
9 ErbB_signaling_pathway_hsa04012 2 85 0.1541 0.8461
10 Gap_junction_hsa04540 2 88 0.1627 0.8461
11 Calcium_signaling_pathway_hsa04020 3 182 0.1881 0.8579
12 HIF_1_signaling_pathway_hsa04066 2 100 0.198 0.8579
13 Regulation_of_actin_cytoskeleton_hsa04810 3 208 0.2435 0.9045
14 Autophagy_animal_hsa04140 2 128 0.2826 0.9346
15 Apelin_signaling_pathway_hsa04371 2 137 0.3099 0.9346
16 Endocytosis_hsa04144 3 244 0.3235 0.9346
17 cGMP_PKG_signaling_pathway_hsa04022 2 163 0.387 1
18 MAPK_signaling_pathway_hsa04010 3 295 0.4365 1
19 Focal_adhesion_hsa04510 2 199 0.4871 1
20 PI3K_Akt_signaling_pathway_hsa04151 3 352 0.5536 1
21 Ras_signaling_pathway_hsa04014 2 232 0.5695 1

Quest ID: 33ced926a62e8214f71447ea441b1fe9