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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-182-5p AATK 3.22 0 -2.47 0 MirTarget -0.32 0 NA
2 hsa-miR-96-5p AATK 3.04 0 -2.47 0 TargetScan -0.2 0.00285 NA
3 hsa-miR-19a-3p ABCA1 2.12 0 -0.92 1.0E-5 miRNAWalker2 validate; MirTarget; miRNATAP -0.16 0 27445062 The target genes of miR-19a such as ABCA1 and PTEN that had been suppressed by miR recovered their expression through CAP treatment
4 hsa-miR-19b-3p ABCA1 2.11 0 -0.92 1.0E-5 MirTarget; miRNATAP -0.2 0 NA
5 hsa-miR-301a-3p ABCA1 2.7 0 -0.92 1.0E-5 miRNATAP -0.17 0 NA
6 hsa-miR-454-3p ABCA1 1.49 0 -0.92 1.0E-5 miRNATAP -0.21 0 NA
7 hsa-miR-96-5p ABCA1 3.04 0 -0.92 1.0E-5 TargetScan; miRNATAP -0.24 0 NA
8 hsa-miR-320a ABCA12 -0.96 0 5.63 0 miRanda; miRNATAP -0.61 0.00083 NA
9 hsa-miR-7-5p ABCA13 0.34 0.43506 0.37 0.52362 MirTarget -0.23 0.00185 NA
10 hsa-miR-320b ABCA4 0.23 0.37882 2.07 0.00169 miRanda -0.51 1.0E-5 NA
11 hsa-miR-320b ABCA8 0.23 0.37882 -4.22 0 miRanda -0.27 0.00358 NA
12 hsa-miR-589-3p ABCC9 1.34 2.0E-5 -1.69 0 mirMAP -0.19 2.0E-5 NA
13 hsa-miR-589-3p ABCD2 1.34 2.0E-5 -0.47 0.13361 MirTarget -0.14 0.00269 NA
14 hsa-miR-19a-3p ABCD3 2.12 0 -0.14 0.33401 MirTarget -0.11 0 NA
15 hsa-miR-19b-3p ABCD3 2.11 0 -0.14 0.33401 MirTarget -0.1 0.00013 NA
16 hsa-miR-576-5p ABCD3 1.03 0 -0.14 0.33401 mirMAP -0.11 0.00054 NA
17 hsa-miR-320a ABCF2 -0.96 0 0.45 1.0E-5 miRNAWalker2 validate -0.1 0.00016 NA
18 hsa-miR-182-5p ABHD2 3.22 0 -0.74 0.00059 mirMAP -0.1 0.00687 NA
19 hsa-miR-19a-3p ABHD2 2.12 0 -0.74 0.00059 mirMAP -0.13 8.0E-5 NA
20 hsa-miR-19b-3p ABHD2 2.11 0 -0.74 0.00059 mirMAP -0.13 0.00157 NA
21 hsa-miR-301a-3p ABHD2 2.7 0 -0.74 0.00059 mirMAP -0.19 0 NA
22 hsa-miR-454-3p ABHD2 1.49 0 -0.74 0.00059 mirMAP -0.24 0 NA
23 hsa-miR-576-5p ABHD2 1.03 0 -0.74 0.00059 mirMAP -0.13 0.00405 NA
24 hsa-miR-96-5p ABHD2 3.04 0 -0.74 0.00059 mirMAP -0.2 0 NA
25 hsa-miR-320a ABHD3 -0.96 0 0.61 0.00031 miRanda -0.15 0.00069 NA
26 hsa-miR-19b-3p ABHD5 2.11 0 -0.85 0 miRNAWalker2 validate -0.14 0 NA
27 hsa-miR-23a-3p ABI2 0.11 0.39309 -0.55 0 mirMAP -0.16 6.0E-5 NA
28 hsa-miR-320b ABI3BP 0.23 0.37882 -3.27 0 miRanda -0.26 0.00024 NA
29 hsa-miR-576-5p ABI3BP 1.03 0 -3.27 0 PITA -0.34 5.0E-5 NA
30 hsa-miR-182-5p ABLIM1 3.22 0 -1.2 0 mirMAP; miRNATAP -0.21 0 NA
31 hsa-miR-320a ACAD8 -0.96 0 0.9 2.0E-5 miRanda -0.16 0.00599 NA
32 hsa-miR-320b ACAD8 0.23 0.37882 0.9 2.0E-5 miRanda -0.17 1.0E-5 NA
33 hsa-miR-23a-3p ACADSB 0.11 0.39309 -0.71 0.001 mirMAP -0.25 0.00103 NA
34 hsa-miR-576-5p ACADSB 1.03 0 -0.71 0.001 mirMAP -0.2 3.0E-5 NA
35 hsa-miR-454-3p ACBD3 1.49 0 0.4 0.001 MirTarget; miRNATAP -0.12 0 NA
36 hsa-miR-96-5p ACER2 3.04 0 -0.46 0.06233 TargetScan -0.14 0.00057 NA
37 hsa-miR-320a ACOT13 -0.96 0 0.35 0.01606 miRanda -0.17 1.0E-5 NA
38 hsa-miR-576-5p ACOX2 1.03 0 -0.57 0.05834 MirTarget -0.35 0 NA
39 hsa-miR-19a-3p ACSL4 2.12 0 -1.28 0 MirTarget; miRNATAP -0.23 0 NA
40 hsa-miR-19b-3p ACSL4 2.11 0 -1.28 0 MirTarget; miRNATAP -0.26 0 NA
41 hsa-miR-301a-3p ACSL4 2.7 0 -1.28 0 MirTarget; miRNATAP -0.23 0 NA
42 hsa-miR-454-3p ACSL4 1.49 0 -1.28 0 MirTarget; miRNATAP -0.29 0 NA
43 hsa-miR-576-5p ACSL4 1.03 0 -1.28 0 mirMAP -0.11 0.01887 NA
44 hsa-miR-320b ACSM5 0.23 0.37882 -1.96 0 miRanda -0.21 0.00531 NA
45 hsa-miR-23a-3p ACSS1 0.11 0.39309 -0.61 0.01833 MirTarget -0.34 0.0002 NA
46 hsa-miR-320a ACTBL2 -0.96 0 1.09 0.01994 miRanda -0.29 0.02284 NA
47 hsa-miR-320b ACTBL2 0.23 0.37882 1.09 0.01994 miRanda -0.29 0.00051 NA
48 hsa-miR-320a ACTL6A -0.96 0 0.81 0 miRanda; miRNATAP -0.18 0 NA
49 hsa-miR-19b-3p ACTN1 2.11 0 -0.11 0.50739 miRNATAP -0.11 0.00021 NA
50 hsa-miR-7-5p ACTN2 0.34 0.43506 -3.89 0 miRNAWalker2 validate -0.2 0.00056 NA
51 hsa-miR-576-5p ACTR8 1.03 0 -0.03 0.69902 MirTarget -0.1 0 NA
52 hsa-miR-19b-3p ACVR1 2.11 0 0.2 0.0862 miRNAWalker2 validate -0.11 0 NA
53 hsa-miR-454-3p ACVR1 1.49 0 0.2 0.0862 MirTarget; miRNATAP -0.15 0 NA
54 hsa-miR-182-5p ACVRL1 3.22 0 -2.59 0 mirMAP -0.44 0 NA
55 hsa-miR-301a-3p ACVRL1 2.7 0 -2.59 0 mirMAP -0.2 0 NA
56 hsa-miR-320a ADAM12 -0.96 0 2.41 0 mirMAP -0.35 0.00204 NA
57 hsa-miR-182-5p ADAM19 3.22 0 0.67 0.00694 miRNATAP -0.19 1.0E-5 NA
58 hsa-miR-96-5p ADAM23 3.04 0 -1.31 0.00188 TargetScan -0.3 3.0E-5 NA
59 hsa-miR-7-5p ADAMTS17 0.34 0.43506 -1.08 0.00084 miRNAWalker2 validate -0.29 0 NA
60 hsa-miR-182-5p ADAMTS4 3.22 0 -0.82 0.02921 MirTarget -0.22 0.00055 NA
61 hsa-miR-19a-3p ADAMTSL3 2.12 0 -3.15 0 miRNATAP -0.29 0 NA
62 hsa-miR-19b-3p ADAMTSL3 2.11 0 -3.15 0 miRNATAP -0.26 0.00017 NA
63 hsa-miR-320b ADAMTSL3 0.23 0.37882 -3.15 0 miRanda -0.15 0.02078 NA
64 hsa-miR-19a-3p ADARB1 2.12 0 -1.88 0 mirMAP -0.11 0.00084 NA
65 hsa-miR-19b-3p ADARB1 2.11 0 -1.88 0 mirMAP -0.13 0.00044 NA
66 hsa-miR-589-3p ADARB1 1.34 2.0E-5 -1.88 0 mirMAP -0.11 0.00026 NA
67 hsa-miR-301a-3p ADCY2 2.7 0 -1.12 0.01473 miRNATAP -0.29 8.0E-5 NA
68 hsa-miR-454-3p ADCY2 1.49 0 -1.12 0.01473 miRNATAP -0.3 0.0026 NA
69 hsa-miR-19a-3p ADCY9 2.12 0 -1.41 0 miRNATAP -0.19 0 NA
70 hsa-miR-19b-3p ADCY9 2.11 0 -1.41 0 miRNATAP -0.18 1.0E-5 NA
71 hsa-miR-7-5p ADCY9 0.34 0.43506 -1.41 0 miRNAWalker2 validate; miRNATAP -0.16 0 NA
72 hsa-miR-576-5p ADCYAP1 1.03 0 -1.16 0.01936 PITA; mirMAP -0.25 0.01963 NA
73 hsa-miR-589-3p ADD2 1.34 2.0E-5 -1.18 0.00449 mirMAP -0.17 0.00848 NA
74 hsa-miR-182-5p ADD3 3.22 0 -0.5 0.03124 MirTarget; miRNATAP -0.15 0.00011 NA
75 hsa-miR-96-5p ADD3 3.04 0 -0.5 0.03124 TargetScan; miRNATAP -0.19 0 NA
76 hsa-miR-320a ADK -0.96 0 0.22 0.21357 miRanda -0.21 1.0E-5 NA
77 hsa-miR-320b ADK 0.23 0.37882 0.22 0.21357 miRanda -0.17 0 NA
78 hsa-miR-320b ADRA1B 0.23 0.37882 -1.57 5.0E-5 miRanda -0.22 0.0019 NA
79 hsa-miR-182-5p ADRA2C 3.22 0 -1.62 7.0E-5 MirTarget -0.24 0.00079 NA
80 hsa-miR-96-5p ADRA2C 3.04 0 -1.62 7.0E-5 TargetScan -0.18 0.00853 NA
81 hsa-miR-320b ADRB2 0.23 0.37882 -3.46 0 miRanda -0.22 0.00057 NA
82 hsa-miR-320a ADSL -0.96 0 0.23 0.06364 miRanda -0.14 4.0E-5 NA
83 hsa-miR-320a ADSS -0.96 0 0.56 0 miRanda -0.11 0.00019 NA
84 hsa-miR-19b-3p AFAP1 2.11 0 0.08 0.60876 mirMAP -0.1 0.00039 NA
85 hsa-miR-454-3p AFF1 1.49 0 -0.48 0.00026 MirTarget -0.12 2.0E-5 NA
86 hsa-miR-182-5p AFF2 3.22 0 -2.23 0 mirMAP -0.26 0.001 NA
87 hsa-miR-19a-3p AFF2 2.12 0 -2.23 0 mirMAP -0.17 0.02002 NA
88 hsa-miR-19b-3p AFF2 2.11 0 -2.23 0 mirMAP -0.17 0.04302 NA
89 hsa-miR-576-5p AFF2 1.03 0 -2.23 0 PITA; mirMAP -0.4 5.0E-5 NA
90 hsa-miR-589-3p AFF2 1.34 2.0E-5 -2.23 0 mirMAP -0.23 0.00063 NA
91 hsa-miR-576-5p AFF4 1.03 0 -0.15 0.22477 mirMAP -0.12 2.0E-5 NA
92 hsa-miR-23a-3p AGAP1 0.11 0.39309 0.27 0.09462 MirTarget; miRNATAP -0.17 0.00348 NA
93 hsa-miR-23a-3p AGK 0.11 0.39309 0.5 0 MirTarget -0.14 0.0001 NA
94 hsa-miR-7-5p AGPAT4 0.34 0.43506 -1.4 0 mirMAP -0.13 1.0E-5 NA
95 hsa-miR-96-5p AHR 3.04 0 -0.23 0.30844 MirTarget; TargetScan; miRNATAP -0.1 0.00757 NA
96 hsa-miR-320b AIF1L 0.23 0.37882 -0.9 0.00256 miRNATAP -0.11 0.04187 NA
97 hsa-miR-320a AIFM2 -0.96 0 0.6 0.00103 miRanda -0.15 0.00177 NA
98 hsa-miR-320b AIM1 0.23 0.37882 -0.49 0.09171 miRanda; miRNATAP -0.18 0.00036 NA
99 hsa-miR-320a AIMP1 -0.96 0 0.24 0.00775 miRanda -0.13 0 NA
100 hsa-miR-96-5p AJAP1 3.04 0 -2.04 0 MirTarget; TargetScan -0.34 0 NA
101 hsa-miR-320a AK2 -0.96 0 0.48 0.00021 miRNAWalker2 validate; PITA; miRanda -0.14 6.0E-5 NA
102 hsa-miR-454-3p AKAP11 1.49 0 -0.62 0 miRNATAP -0.2 0 NA
103 hsa-miR-589-3p AKAP13 1.34 2.0E-5 -1.2 0 mirMAP -0.13 0 NA
104 hsa-miR-19a-3p AKAP2 2.12 0 -2.97 0 mirMAP -0.25 0 NA
105 hsa-miR-19b-3p AKAP2 2.11 0 -2.97 0 mirMAP -0.35 0 NA
106 hsa-miR-576-5p AKAP2 1.03 0 -2.97 0 mirMAP -0.21 0.0007 NA
107 hsa-miR-320b AKAP6 0.23 0.37882 -0.99 0.00066 miRanda -0.16 0.00165 NA
108 hsa-miR-182-5p AKAP7 3.22 0 -1.32 0 miRNATAP -0.24 0 NA
109 hsa-miR-301a-3p AKAP7 2.7 0 -1.32 0 miRNATAP -0.16 0 NA
110 hsa-miR-454-3p AKAP7 1.49 0 -1.32 0 miRNATAP -0.18 2.0E-5 NA
111 hsa-miR-96-5p AKAP7 3.04 0 -1.32 0 miRNATAP -0.31 0 NA
112 hsa-miR-576-5p ALAD 1.03 0 -0.42 0.00031 mirMAP -0.13 0 NA
113 hsa-miR-301a-3p ALDH5A1 2.7 0 -0.09 0.63947 mirMAP -0.14 1.0E-5 NA
114 hsa-miR-454-3p ALDH5A1 1.49 0 -0.09 0.63947 mirMAP -0.1 0.01542 NA
115 hsa-miR-576-5p ALDH6A1 1.03 0 -0.33 0.09417 mirMAP -0.19 1.0E-5 NA
116 hsa-miR-23a-3p ALG13 0.11 0.39309 0.25 0.02085 MirTarget -0.12 0.00313 NA
117 hsa-miR-320a AMACR -0.96 0 0.6 0.00099 miRanda -0.18 0.00018 NA
118 hsa-miR-320b AMOT 0.23 0.37882 -0.3 0.45043 miRanda -0.21 0.00363 NA
119 hsa-miR-576-5p AMOT 1.03 0 -0.3 0.45043 mirMAP -0.3 0.00043 NA
120 hsa-miR-301a-3p AMOTL1 2.7 0 -2.04 0 mirMAP -0.22 0 NA
121 hsa-miR-454-3p AMOTL1 1.49 0 -2.04 0 mirMAP -0.24 0 NA
122 hsa-miR-182-5p AMOTL2 3.22 0 -1.1 0 miRNATAP -0.18 0 NA
123 hsa-miR-96-5p AMOTL2 3.04 0 -1.1 0 TargetScan; miRNATAP -0.15 0 NA
124 hsa-miR-320b AMY2B 0.23 0.37882 0.27 0.43071 miRanda -0.19 0.00192 NA
125 hsa-miR-96-5p AMZ1 3.04 0 -0.26 0.45366 mirMAP -0.18 0.00257 NA
126 hsa-miR-19b-3p ANGPT2 2.11 0 -0.36 0.23492 MirTarget -0.14 0.01464 NA
127 hsa-miR-320b ANGPTL1 0.23 0.37882 -3.34 0 miRanda; miRNATAP -0.13 0.04582 NA
128 hsa-miR-182-5p ANK2 3.22 0 -1.34 2.0E-5 miRNATAP -0.36 0 NA
129 hsa-miR-182-5p ANK3 3.22 0 -1.32 0 MirTarget; miRNATAP -0.15 0.00154 NA
130 hsa-miR-19b-3p ANKH 2.11 0 0 0.99073 mirMAP -0.11 0.00357 NA
131 hsa-miR-589-3p ANKH 1.34 2.0E-5 0 0.99073 mirMAP -0.1 0.00052 NA
132 hsa-miR-126-5p ANKRD34B 0.85 0.00039 3.03 1.0E-5 mirMAP -0.34 0.0111 NA
133 hsa-miR-320a ANKRD39 -0.96 0 0.69 0 miRNAWalker2 validate -0.14 0.00053 NA
134 hsa-miR-320b ANKRD44 0.23 0.37882 -1.36 0 miRanda -0.2 5.0E-5 NA
135 hsa-miR-320a ANKRD46 -0.96 0 -0.38 0.01504 miRanda -0.1 0.0163 NA
136 hsa-miR-576-5p ANKRD46 1.03 0 -0.38 0.01504 MirTarget; PITA -0.13 9.0E-5 NA
137 hsa-miR-576-5p ANKRD50 1.03 0 -0.3 0.07201 MirTarget; mirMAP -0.15 2.0E-5 NA
138 hsa-miR-126-5p ANLN 0.85 0.00039 3.51 0 mirMAP -0.16 0.02617 NA
139 hsa-miR-19a-3p ANO1 2.12 0 -0.71 0.02851 MirTarget; miRNATAP -0.2 8.0E-5 NA
140 hsa-miR-19b-3p ANO1 2.11 0 -0.71 0.02851 MirTarget; miRNATAP -0.2 0.00085 NA
141 hsa-miR-23a-3p ANO5 0.11 0.39309 -1.91 2.0E-5 mirMAP -0.48 0.00325 NA
142 hsa-miR-182-5p ANO6 3.22 0 -1.11 0 miRNAWalker2 validate -0.19 0 NA
143 hsa-miR-576-5p ANO6 1.03 0 -1.11 0 MirTarget; mirMAP -0.12 0.00021 NA
144 hsa-miR-96-5p ANPEP 3.04 0 -1.32 0.00087 mirMAP -0.32 0 NA
145 hsa-miR-19a-3p ANTXR1 2.12 0 -0.82 0.00129 MirTarget; mirMAP -0.27 0 NA
146 hsa-miR-19b-3p ANTXR1 2.11 0 -0.82 0.00129 MirTarget -0.34 0 NA
147 hsa-miR-576-5p ANTXR1 1.03 0 -0.82 0.00129 MirTarget; PITA -0.36 0 NA
148 hsa-miR-182-5p ANTXR2 3.22 0 -0.2 0.28312 miRNATAP -0.12 0.00011 NA
149 hsa-miR-576-5p ANTXR2 1.03 0 -0.2 0.28312 mirMAP -0.18 1.0E-5 NA
150 hsa-miR-96-5p ANTXR2 3.04 0 -0.2 0.28312 TargetScan; miRNATAP -0.19 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 CELL DEVELOPMENT 324 1426 2.958e-26 1.376e-22
2 TISSUE DEVELOPMENT 338 1518 9.403e-26 2.188e-22
3 RESPONSE TO ENDOGENOUS STIMULUS 317 1450 9.196e-23 1.066e-19
4 REGULATION OF CELL DIFFERENTIATION 324 1492 9.121e-23 1.066e-19
5 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 287 1275 1.375e-22 1.066e-19
6 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 241 1008 1.226e-22 1.066e-19
7 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 352 1672 2.69e-22 1.788e-19
8 REGULATION OF CELL PROLIFERATION 322 1496 5.687e-22 3.308e-19
9 LOCOMOTION 254 1114 8.228e-21 4.254e-18
10 CARDIOVASCULAR SYSTEM DEVELOPMENT 195 788 3.329e-20 1.408e-17
11 CIRCULATORY SYSTEM DEVELOPMENT 195 788 3.329e-20 1.408e-17
12 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 298 1395 7.904e-20 3.065e-17
13 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 371 1848 9.091e-20 3.254e-17
14 POSITIVE REGULATION OF GENE EXPRESSION 351 1733 2.506e-19 8.329e-17
15 VASCULATURE DEVELOPMENT 132 469 7.231e-19 2.243e-16
16 REGULATION OF CELLULAR COMPONENT MOVEMENT 188 771 8.941e-19 2.6e-16
17 NEUROGENESIS 295 1402 1.202e-18 3.29e-16
18 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 231 1021 1.521e-18 3.933e-16
19 POSITIVE REGULATION OF MOLECULAR FUNCTION 356 1791 3.045e-18 7.458e-16
20 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 219 957 3.21e-18 7.469e-16
21 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 354 1784 5.108e-18 1.132e-15
22 INTRACELLULAR SIGNAL TRANSDUCTION 319 1572 1.079e-17 2.283e-15
23 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 170 689 1.341e-17 2.712e-15
24 CELLULAR COMPONENT MORPHOGENESIS 207 900 1.609e-17 3.119e-15
25 REGULATION OF TRANSPORT 353 1804 5.391e-17 1.003e-14
26 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 352 1805 1.026e-16 1.836e-14
27 EPITHELIUM DEVELOPMENT 212 945 1.184e-16 2.012e-14
28 CELL MOTILITY 193 835 1.254e-16 2.012e-14
29 LOCALIZATION OF CELL 193 835 1.254e-16 2.012e-14
30 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 243 1142 4.797e-16 7.44e-14
31 POSITIVE REGULATION OF CELL PROLIFERATION 187 814 7.318e-16 1.098e-13
32 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 133 513 8.256e-16 1.201e-13
33 REGULATION OF PHOSPHORUS METABOLIC PROCESS 317 1618 2.332e-15 3.288e-13
34 POSITIVE REGULATION OF CATALYTIC ACTIVITY 301 1518 2.613e-15 3.492e-13
35 HEAD DEVELOPMENT 167 709 2.627e-15 3.492e-13
36 BLOOD VESSEL MORPHOGENESIS 103 364 3.61e-15 4.667e-13
37 POSITIVE REGULATION OF CELL DIFFERENTIATION 186 823 4.735e-15 5.955e-13
38 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 321 1656 6.831e-15 8.364e-13
39 ORGAN MORPHOGENESIS 188 841 1.023e-14 1.22e-12
40 MUSCLE STRUCTURE DEVELOPMENT 115 432 1.058e-14 1.23e-12
41 NEURON PROJECTION MORPHOGENESIS 109 402 1.387e-14 1.574e-12
42 SKELETAL SYSTEM DEVELOPMENT 119 455 1.434e-14 1.589e-12
43 TISSUE MORPHOGENESIS 133 533 2.037e-14 2.188e-12
44 BIOLOGICAL ADHESION 219 1032 2.069e-14 2.188e-12
45 REGULATION OF PROTEIN MODIFICATION PROCESS 327 1710 2.475e-14 2.559e-12
46 TUBE DEVELOPMENT 136 552 2.961e-14 2.996e-12
47 NEURON DIFFERENTIATION 191 874 6.143e-14 6.081e-12
48 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 212 1004 9.457e-14 9.167e-12
49 MUSCLE CELL DIFFERENTIATION 74 237 1.293e-13 1.228e-11
50 EMBRYO DEVELOPMENT 193 894 1.522e-13 1.417e-11
51 NEURON PROJECTION DEVELOPMENT 132 545 2.774e-13 2.531e-11
52 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 99 368 3.837e-13 3.433e-11
53 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 175 799 5.99e-13 5.259e-11
54 CENTRAL NERVOUS SYSTEM DEVELOPMENT 187 872 7.027e-13 6.055e-11
55 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 175 801 7.525e-13 6.366e-11
56 REGULATION OF EPITHELIAL CELL PROLIFERATION 82 285 8.927e-13 7.418e-11
57 EMBRYONIC MORPHOGENESIS 129 539 1.29e-12 1.053e-10
58 CELL PROJECTION ORGANIZATION 191 902 1.323e-12 1.061e-10
59 NEGATIVE REGULATION OF CELL PROLIFERATION 147 643 1.549e-12 1.222e-10
60 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 70 229 1.831e-12 1.396e-10
61 RESPONSE TO HORMONE 189 893 1.83e-12 1.396e-10
62 RESPONSE TO OXYGEN CONTAINING COMPOUND 267 1381 2.339e-12 1.755e-10
63 POSITIVE REGULATION OF RESPONSE TO STIMULUS 351 1929 2.726e-12 2.014e-10
64 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 284 1492 2.777e-12 2.019e-10
65 REGULATION OF NEURON DIFFERENTIATION 130 554 4.646e-12 3.326e-10
66 REGULATION OF CELL DEVELOPMENT 178 836 4.927e-12 3.474e-10
67 RESPONSE TO ORGANIC CYCLIC COMPOUND 191 917 6.206e-12 4.31e-10
68 PROTEIN PHOSPHORYLATION 195 944 8.005e-12 5.478e-10
69 REGULATION OF KINASE ACTIVITY 167 776 9.422e-12 6.354e-10
70 REGULATION OF CELL ADHESION 142 629 1e-11 6.649e-10
71 MUSCLE SYSTEM PROCESS 79 282 1.027e-11 6.734e-10
72 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 119 498 1.085e-11 7.011e-10
73 CELL PROLIFERATION 149 672 1.284e-11 8.185e-10
74 ACTIN FILAMENT BASED PROCESS 110 450 1.502e-11 9.441e-10
75 REGULATION OF HOMEOSTATIC PROCESS 109 447 2.181e-11 1.353e-09
76 STRIATED MUSCLE CELL DIFFERENTIATION 56 173 2.461e-11 1.507e-09
77 REGULATION OF CELLULAR LOCALIZATION 246 1277 2.747e-11 1.66e-09
78 CELLULAR RESPONSE TO NITROGEN COMPOUND 119 505 2.839e-11 1.693e-09
79 CELLULAR RESPONSE TO HORMONE STIMULUS 127 552 3.384e-11 1.968e-09
80 REGULATION OF CELL MORPHOGENESIS 127 552 3.384e-11 1.968e-09
81 NEURON DEVELOPMENT 150 687 3.667e-11 2.106e-09
82 POSITIVE REGULATION OF LOCOMOTION 103 420 5.474e-11 3.075e-09
83 NEURON PROJECTION GUIDANCE 62 205 5.485e-11 3.075e-09
84 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 198 983 5.655e-11 3.132e-09
85 CELL PART MORPHOGENESIS 140 633 6.541e-11 3.539e-09
86 REGULATION OF ION TRANSPORT 133 592 6.524e-11 3.539e-09
87 MORPHOGENESIS OF AN EPITHELIUM 99 400 7.463e-11 3.991e-09
88 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 155 724 8.119e-11 4.293e-09
89 REGULATION OF CELL DEATH 274 1472 8.542e-11 4.466e-09
90 POSITIVE REGULATION OF CELL COMMUNICATION 283 1532 9.417e-11 4.869e-09
91 RESPONSE TO NITROGEN COMPOUND 177 859 9.598e-11 4.907e-09
92 RESPONSE TO GROWTH FACTOR 112 475 1.049e-10 5.303e-09
93 REGULATION OF ACTIN FILAMENT BASED PROCESS 82 312 1.414e-10 7.075e-09
94 REGULATION OF TRANSFERASE ACTIVITY 190 946 1.816e-10 8.987e-09
95 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 220 1135 1.89e-10 9.258e-09
96 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 348 1977 2.412e-10 1.169e-08
97 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 61 207 2.52e-10 1.209e-08
98 MUSCLE CONTRACTION 66 233 3.048e-10 1.446e-08
99 HEART DEVELOPMENT 109 466 3.077e-10 1.446e-08
100 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 157 750 3.494e-10 1.626e-08
101 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 203 1036 3.877e-10 1.769e-08
102 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 203 1036 3.877e-10 1.769e-08
103 POSITIVE REGULATION OF TRANSPORT 187 936 3.986e-10 1.801e-08
104 FOREBRAIN DEVELOPMENT 89 357 4.553e-10 2.037e-08
105 REGULATION OF GROWTH 137 633 4.91e-10 2.176e-08
106 TAXIS 108 464 5.014e-10 2.201e-08
107 REGULATION OF TRANSMEMBRANE TRANSPORT 101 426 6.307e-10 2.743e-08
108 REGULATION OF ANATOMICAL STRUCTURE SIZE 109 472 6.75e-10 2.881e-08
109 POSITIVE REGULATION OF CELL DEVELOPMENT 109 472 6.75e-10 2.881e-08
110 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 47 144 7.04e-10 2.951e-08
111 RESPONSE TO ABIOTIC STIMULUS 200 1024 6.98e-10 2.951e-08
112 NEGATIVE REGULATION OF CELL COMMUNICATION 226 1192 8.457e-10 3.513e-08
113 RESPONSE TO STEROID HORMONE 113 497 8.673e-10 3.571e-08
114 POSITIVE REGULATION OF KINASE ACTIVITY 110 482 1.159e-09 4.732e-08
115 REGULATION OF PROTEIN LOCALIZATION 187 950 1.368e-09 5.534e-08
116 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 84 337 1.409e-09 5.558e-08
117 UROGENITAL SYSTEM DEVELOPMENT 77 299 1.405e-09 5.558e-08
118 EPITHELIAL CELL DIFFERENTIATION 112 495 1.386e-09 5.558e-08
119 NEGATIVE REGULATION OF GENE EXPRESSION 271 1493 1.525e-09 5.962e-08
120 RESPONSE TO OXYGEN LEVELS 79 311 1.709e-09 6.626e-08
121 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 132 616 1.991e-09 7.658e-08
122 TUBE MORPHOGENESIS 81 323 2.04e-09 7.78e-08
123 MUSCLE TISSUE DEVELOPMENT 72 275 2.216e-09 8.381e-08
124 REGULATION OF SYSTEM PROCESS 113 507 2.923e-09 1.097e-07
125 ANGIOGENESIS 75 293 3.053e-09 1.136e-07
126 POSITIVE REGULATION OF HYDROLASE ACTIVITY 178 905 3.694e-09 1.353e-07
127 REGULATION OF CELL CYCLE 185 949 3.666e-09 1.353e-07
128 REGULATION OF MUSCLE SYSTEM PROCESS 56 195 3.826e-09 1.391e-07
129 POSITIVE REGULATION OF NEURON DIFFERENTIATION 77 306 4.306e-09 1.553e-07
130 GLAND DEVELOPMENT 93 395 4.351e-09 1.557e-07
131 RESPONSE TO ALCOHOL 87 362 4.838e-09 1.718e-07
132 REGULATION OF GTPASE ACTIVITY 140 673 4.931e-09 1.738e-07
133 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 216 1152 5.428e-09 1.885e-07
134 REGULATION OF NEURON PROJECTION DEVELOPMENT 95 408 5.412e-09 1.885e-07
135 REGULATION OF INTRACELLULAR TRANSPORT 131 621 6.368e-09 2.195e-07
136 REGULATION OF CYTOSKELETON ORGANIZATION 111 502 6.434e-09 2.201e-07
137 RESPONSE TO EXTERNAL STIMULUS 316 1821 8.743e-09 2.949e-07
138 REGULATION OF CELL PROJECTION ORGANIZATION 120 558 8.745e-09 2.949e-07
139 IMMUNE SYSTEM DEVELOPMENT 124 582 8.816e-09 2.951e-07
140 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 105 470 9.29e-09 3.088e-07
141 NEGATIVE REGULATION OF CELL DIFFERENTIATION 128 609 1.195e-08 3.944e-07
142 RESPONSE TO LIPID 173 888 1.26e-08 4.13e-07
143 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 246 1360 1.291e-08 4.201e-07
144 CELL ACTIVATION 121 568 1.346e-08 4.35e-07
145 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 35 100 1.357e-08 4.355e-07
146 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 149 740 1.516e-08 4.831e-07
147 REGULATION OF CELLULAR COMPONENT SIZE 81 337 1.619e-08 5.126e-07
148 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 43 138 1.759e-08 5.531e-07
149 REGULATION OF HYDROLASE ACTIVITY 240 1327 1.996e-08 6.197e-07
150 CELL CELL ADHESION 127 608 1.998e-08 6.197e-07
151 CELL CYCLE 238 1316 2.308e-08 7.112e-07
152 RESPONSE TO WOUNDING 119 563 2.813e-08 8.611e-07
153 REGULATION OF CELLULAR COMPONENT BIOGENESIS 152 767 3.197e-08 9.692e-07
154 ACTION POTENTIAL 33 94 3.208e-08 9.692e-07
155 REGULATION OF CYTOPLASMIC TRANSPORT 105 481 3.326e-08 9.985e-07
156 WOUND HEALING 103 470 3.645e-08 1.087e-06
157 REGULATION OF EPITHELIAL CELL MIGRATION 48 166 3.824e-08 1.133e-06
158 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 267 1517 3.966e-08 1.168e-06
159 MEMBRANE DEPOLARIZATION DURING CARDIAC MUSCLE CELL ACTION POTENTIAL 11 14 4.175e-08 1.222e-06
160 POSITIVE REGULATION OF FIBROBLAST PROLIFERATION 23 53 4.24e-08 1.233e-06
161 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 56 208 4.641e-08 1.341e-06
162 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 97 437 4.73e-08 1.359e-06
163 REGULATION OF OSSIFICATION 50 178 5.597e-08 1.598e-06
164 PHOSPHORYLATION 222 1228 7.323e-08 2.078e-06
165 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 60 232 7.556e-08 2.131e-06
166 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 101 465 7.856e-08 2.202e-06
167 REGULATION OF MEMBRANE POTENTIAL 80 343 7.938e-08 2.212e-06
168 TELENCEPHALON DEVELOPMENT 59 228 9.458e-08 2.619e-06
169 REGULATION OF CELL GROWTH 88 391 1.024e-07 2.819e-06
170 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 115 554 1.317e-07 3.555e-06
171 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 33 99 1.329e-07 3.555e-06
172 REGULATION OF IMMUNE SYSTEM PROCESS 247 1403 1.314e-07 3.555e-06
173 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 33 99 1.329e-07 3.555e-06
174 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 46 162 1.321e-07 3.555e-06
175 REGULATION OF ORGANELLE ORGANIZATION 213 1178 1.351e-07 3.591e-06
176 CELLULAR RESPONSE TO PEPTIDE 67 274 1.381e-07 3.65e-06
177 REGULATION OF METAL ION TRANSPORT 76 325 1.485e-07 3.883e-06
178 CARDIAC MUSCLE CELL ACTION POTENTIAL 18 37 1.484e-07 3.883e-06
179 REGULATION OF MAPK CASCADE 132 660 1.517e-07 3.943e-06
180 REGULATION OF CELL SUBSTRATE ADHESION 48 173 1.544e-07 3.99e-06
181 MUSCLE CELL DEVELOPMENT 39 128 1.553e-07 3.991e-06
182 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 72 303 1.614e-07 4.125e-06
183 REGULATION OF HEART CONTRACTION 57 221 1.748e-07 4.446e-06
184 REGULATION OF CATABOLIC PROCESS 143 731 1.845e-07 4.666e-06
185 REGULATION OF CELLULAR PROTEIN LOCALIZATION 114 552 1.97e-07 4.954e-06
186 NEGATIVE REGULATION OF CELL DEATH 165 872 2.049e-07 5.127e-06
187 CATION TRANSPORT 153 796 2.14e-07 5.325e-06
188 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 36 115 2.184e-07 5.406e-06
189 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 164 867 2.282e-07 5.618e-06
190 SENSORY ORGAN DEVELOPMENT 104 493 2.315e-07 5.67e-06
191 REGULATION OF DEVELOPMENTAL GROWTH 69 289 2.396e-07 5.837e-06
192 ION TRANSPORT 224 1262 2.791e-07 6.763e-06
193 POSITIVE REGULATION OF CELL DEATH 122 605 2.847e-07 6.865e-06
194 EMBRYONIC ORGAN DEVELOPMENT 89 406 3.004e-07 7.204e-06
195 ACTIN FILAMENT BASED MOVEMENT 31 93 3.159e-07 7.538e-06
196 REGULATION OF TRANSPORTER ACTIVITY 52 198 3.243e-07 7.7e-06
197 METAL ION TRANSPORT 118 582 3.325e-07 7.852e-06
198 REGULATION OF MUSCLE CONTRACTION 42 147 3.793e-07 8.874e-06
199 RHYTHMIC PROCESS 70 298 3.795e-07 8.874e-06
200 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 111 541 4.006e-07 9.274e-06
201 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 111 541 4.006e-07 9.274e-06
202 CONNECTIVE TISSUE DEVELOPMENT 51 194 4.057e-07 9.344e-06
203 REGULATION OF AXONOGENESIS 46 168 4.214e-07 9.659e-06
204 CELLULAR RESPONSE TO LIPID 97 457 4.365e-07 9.956e-06
205 MULTICELLULAR ORGANISMAL SIGNALING 37 123 4.563e-07 1.036e-05
206 NEGATIVE REGULATION OF PHOSPHORYLATION 91 422 4.779e-07 1.079e-05
207 STEM CELL DIFFERENTIATION 50 190 5.074e-07 1.14e-05
208 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 79 352 5.11e-07 1.143e-05
209 REGULATION OF BLOOD CIRCULATION 69 295 5.422e-07 1.207e-05
210 REGULATION OF CHEMOTAXIS 48 180 5.595e-07 1.24e-05
211 ACTOMYOSIN STRUCTURE ORGANIZATION 27 77 5.74e-07 1.266e-05
212 REGULATION OF CELL ACTIVATION 101 484 5.868e-07 1.288e-05
213 CARDIAC MUSCLE CELL CONTRACTION 15 29 5.943e-07 1.298e-05
214 EMBRYONIC ORGAN MORPHOGENESIS 66 279 6.182e-07 1.344e-05
215 BEHAVIOR 106 516 6.851e-07 1.483e-05
216 CARDIAC MUSCLE TISSUE DEVELOPMENT 40 140 7.113e-07 1.532e-05
217 EXTRACELLULAR STRUCTURE ORGANIZATION 70 304 8.34e-07 1.788e-05
218 REGULATION OF BODY FLUID LEVELS 104 506 8.489e-07 1.812e-05
219 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 87 404 8.996e-07 1.911e-05
220 RESPONSE TO MECHANICAL STIMULUS 53 210 9.635e-07 2.038e-05
221 SINGLE ORGANISM CELL ADHESION 96 459 9.983e-07 2.092e-05
222 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 170 926 9.969e-07 2.092e-05
223 POSITIVE REGULATION OF CELL ADHESION 82 376 1.079e-06 2.252e-05
224 REGULATION OF VASCULATURE DEVELOPMENT 57 233 1.134e-06 2.356e-05
225 POSITIVE REGULATION OF OSSIFICATION 28 84 1.16e-06 2.399e-05
226 CELL DEATH 181 1001 1.227e-06 2.527e-05
227 PLATELET DERIVED GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 16 34 1.293e-06 2.65e-05
228 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 68 296 1.299e-06 2.651e-05
229 AMEBOIDAL TYPE CELL MIGRATION 42 154 1.474e-06 2.996e-05
230 HEART PROCESS 28 85 1.518e-06 3.07e-05
231 NEGATIVE REGULATION OF CELL CYCLE 91 433 1.531e-06 3.084e-05
232 POSITIVE REGULATION OF MAPK CASCADE 97 470 1.629e-06 3.267e-05
233 REGULATION OF RESPONSE TO STRESS 250 1468 1.704e-06 3.392e-05
234 GROWTH 87 410 1.71e-06 3.392e-05
235 DEVELOPMENTAL GROWTH 74 333 1.713e-06 3.392e-05
236 MITOTIC CELL CYCLE 144 766 1.796e-06 3.527e-05
237 REGULATION OF FIBROBLAST PROLIFERATION 27 81 1.791e-06 3.527e-05
238 SYNAPSE ORGANIZATION 40 145 1.898e-06 3.71e-05
239 CYTOSKELETON ORGANIZATION 155 838 1.936e-06 3.753e-05
240 VASCULOGENESIS 22 59 1.928e-06 3.753e-05
241 REGULATION OF CELL SIZE 45 172 2.191e-06 4.229e-05
242 CARDIAC CONDUCTION 27 82 2.343e-06 4.505e-05
243 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 33 111 2.494e-06 4.776e-05
244 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 35 121 2.523e-06 4.812e-05
245 RESPONSE TO ACID CHEMICAL 71 319 2.597e-06 4.933e-05
246 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 22 60 2.675e-06 5.059e-05
247 MESENCHYME DEVELOPMENT 48 190 2.979e-06 5.577e-05
248 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 31 102 2.984e-06 5.577e-05
249 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 48 190 2.979e-06 5.577e-05
250 REGULATION OF ION HOMEOSTASIS 50 201 3.022e-06 5.624e-05
251 APPENDAGE DEVELOPMENT 44 169 3.249e-06 5.998e-05
252 LIMB DEVELOPMENT 44 169 3.249e-06 5.998e-05
253 IMMUNE SYSTEM PROCESS 323 1984 3.284e-06 6.04e-05
254 LEUKOCYTE DIFFERENTIATION 66 292 3.332e-06 6.104e-05
255 CELLULAR RESPONSE TO OXYGEN LEVELS 39 143 3.441e-06 6.28e-05
256 PROTEIN LOCALIZATION 297 1805 3.533e-06 6.422e-05
257 CELLULAR RESPONSE TO STRESS 262 1565 3.735e-06 6.762e-05
258 REGULATION OF STEM CELL DIFFERENTIATION 33 113 3.842e-06 6.929e-05
259 PLASMA MEMBRANE ORGANIZATION 50 203 4.09e-06 7.347e-05
260 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 53 220 4.313e-06 7.719e-05
261 REGULATION OF MITOTIC CELL CYCLE 95 468 4.335e-06 7.728e-05
262 POSITIVE REGULATION OF CATABOLIC PROCESS 83 395 4.376e-06 7.772e-05
263 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 159 876 4.412e-06 7.805e-05
264 CELL JUNCTION ASSEMBLY 36 129 4.551e-06 8.021e-05
265 SINGLE ORGANISM BEHAVIOR 81 384 4.875e-06 8.513e-05
266 CIRCULATORY SYSTEM PROCESS 78 366 4.875e-06 8.513e-05
267 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 19 49 4.885e-06 8.513e-05
268 REGULATION OF CELL MATRIX ADHESION 28 90 5.364e-06 9.312e-05
269 REGULATION OF PEPTIDE TRANSPORT 59 256 5.716e-06 9.887e-05
270 SENSORY ORGAN MORPHOGENESIS 56 239 5.783e-06 9.967e-05
271 POSITIVE REGULATION OF CELL CYCLE 72 332 5.878e-06 0.0001009
272 CELLULAR RESPONSE TO INSULIN STIMULUS 39 146 5.935e-06 0.0001015
273 CARDIOCYTE DIFFERENTIATION 29 96 7.022e-06 0.0001197
274 CARTILAGE DEVELOPMENT 39 147 7.081e-06 0.0001203
275 CELL JUNCTION ORGANIZATION 46 185 7.466e-06 0.0001263
276 REGULATION OF CELL JUNCTION ASSEMBLY 23 68 7.761e-06 0.0001308
277 REGULATION OF LIPID METABOLIC PROCESS 63 282 8.193e-06 0.0001376
278 MEMBRANE ORGANIZATION 161 899 8.406e-06 0.0001407
279 CELLULAR RESPONSE TO ACID CHEMICAL 44 175 8.614e-06 0.000143
280 RESPIRATORY SYSTEM DEVELOPMENT 48 197 8.639e-06 0.000143
281 REGULATION OF ORGAN MORPHOGENESIS 56 242 8.593e-06 0.000143
282 EPITHELIAL CELL DEVELOPMENT 46 186 8.692e-06 0.0001434
283 REGULATION OF OSTEOBLAST DIFFERENTIATION 32 112 8.865e-06 0.0001458
284 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 64 289 9.4e-06 0.000154
285 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 40 154 9.464e-06 0.0001543
286 NEGATIVE REGULATION OF TRANSPORT 92 458 9.485e-06 0.0001543
287 REGULATION OF POTASSIUM ION TRANSPORT 26 83 1e-05 0.0001621
288 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 62 278 1.019e-05 0.0001641
289 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 117 616 1.017e-05 0.0001641
290 POSITIVE REGULATION OF AXONOGENESIS 23 69 1.023e-05 0.0001641
291 REGULATION OF SMOOTH MUSCLE CONTRACTION 21 60 1.044e-05 0.0001666
292 REGULATION OF CATION CHANNEL ACTIVITY 27 88 1.046e-05 0.0001666
293 CARDIAC CHAMBER DEVELOPMENT 38 144 1.055e-05 0.0001676
294 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 30 103 1.102e-05 0.0001744
295 CELL DIVISION 92 460 1.136e-05 0.0001792
296 MESENCHYMAL CELL DIFFERENTIATION 36 134 1.16e-05 0.0001817
297 RESPONSE TO MINERALOCORTICOID 15 35 1.159e-05 0.0001817
298 MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL 16 39 1.168e-05 0.0001823
299 RESPONSE TO INORGANIC SUBSTANCE 95 479 1.173e-05 0.0001826
300 TUBE FORMATION 35 129 1.208e-05 0.0001874
301 WNT SIGNALING PATHWAY 74 351 1.253e-05 0.0001937
302 CELLULAR MACROMOLECULE LOCALIZATION 210 1234 1.264e-05 0.0001948
303 OSSIFICATION 57 251 1.301e-05 0.0001998
304 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 88 437 1.331e-05 0.0002037
305 NEURAL TUBE FORMATION 28 94 1.347e-05 0.0002054
306 PROTEIN LOCALIZATION TO CELL PERIPHERY 39 151 1.402e-05 0.0002125
307 REGULATION OF POTASSIUM ION TRANSMEMBRANE TRANSPORT 21 61 1.4e-05 0.0002125
308 CELL CYCLE PROCESS 187 1081 1.433e-05 0.0002165
309 NEURAL CREST CELL DIFFERENTIATION 24 75 1.452e-05 0.0002186
310 CELLULAR CHEMICAL HOMEOSTASIS 109 570 1.494e-05 0.0002242
311 CYTOKINE PRODUCTION 33 120 1.563e-05 0.0002338
312 REGULATION OF CELL CYCLE PROCESS 107 558 1.579e-05 0.0002354
313 CARDIAC SEPTUM DEVELOPMENT 26 85 1.608e-05 0.0002383
314 CELLULAR RESPONSE TO ALCOHOL 32 115 1.608e-05 0.0002383
315 POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 29 100 1.681e-05 0.0002483
316 MULTI MULTICELLULAR ORGANISM PROCESS 50 213 1.692e-05 0.0002492
317 REGULATION OF ERYTHROCYTE DIFFERENTIATION 15 36 1.75e-05 0.0002569
318 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 38 147 1.758e-05 0.0002572
319 ENDOMEMBRANE SYSTEM ORGANIZATION 92 465 1.768e-05 0.0002579
320 MUSCLE ORGAN DEVELOPMENT 61 277 1.802e-05 0.000262
321 REGULATION OF CALCIUM MEDIATED SIGNALING 24 76 1.864e-05 0.0002702
322 REGULATION OF MAP KINASE ACTIVITY 68 319 1.907e-05 0.0002755
323 MONOVALENT INORGANIC CATION TRANSPORT 87 435 1.945e-05 0.0002785
324 NEGATIVE REGULATION OF CELL CYCLE PROCESS 50 214 1.935e-05 0.0002785
325 PALLIUM DEVELOPMENT 39 153 1.946e-05 0.0002785
326 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 187 1087 2.005e-05 0.0002862
327 REGULATION OF CELL CELL ADHESION 78 380 2.014e-05 0.0002866
328 REGULATION OF HEART RATE 26 86 2.024e-05 0.0002872
329 REGULATION OF PROTEIN CATABOLIC PROCESS 80 393 2.165e-05 0.0003062
330 MEMBRANE ASSEMBLY 12 25 2.179e-05 0.0003072
331 EAR MORPHOGENESIS 31 112 2.43e-05 0.0003416
332 REGULATION OF SECRETION 128 699 2.458e-05 0.0003444
333 REGULATION OF MEMBRANE DEPOLARIZATION 16 41 2.474e-05 0.0003457
334 INNER EAR MORPHOGENESIS 27 92 2.563e-05 0.0003571
335 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 99 514 2.695e-05 0.0003743
336 LEUKOCYTE ACTIVATION 83 414 2.732e-05 0.000378
337 NEGATIVE REGULATION OF LOCOMOTION 58 263 2.738e-05 0.000378
338 REPRODUCTIVE SYSTEM DEVELOPMENT 82 408 2.777e-05 0.0003823
339 REGULATION OF PROTEIN IMPORT 44 183 2.847e-05 0.0003908
340 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 35 134 2.928e-05 0.0004007
341 POSITIVE REGULATION OF MUSCLE HYPERTROPHY 11 22 2.978e-05 0.0004016
342 CELL CELL SIGNALING INVOLVED IN CARDIAC CONDUCTION 11 22 2.978e-05 0.0004016
343 CENTRAL NERVOUS SYSTEM PROJECTION NEURON AXONOGENESIS 11 22 2.978e-05 0.0004016
344 POSITIVE REGULATION OF CARDIAC MUSCLE HYPERTROPHY 11 22 2.978e-05 0.0004016
345 NEGATIVE REGULATION OF CELL ADHESION 51 223 2.967e-05 0.0004016
346 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 76 372 3.023e-05 0.0004065
347 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 74 360 3.089e-05 0.0004142
348 NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 28 98 3.15e-05 0.0004212
349 CHEMICAL HOMEOSTASIS 154 874 3.165e-05 0.000422
350 RESPONSE TO PEPTIDE 81 404 3.386e-05 0.0004502
351 LEUKOCYTE MIGRATION 57 259 3.4e-05 0.0004508
352 REGULATION OF ENDOTHELIAL CELL MIGRATION 31 114 3.541e-05 0.0004681
353 REGULATION OF HOMOTYPIC CELL CELL ADHESION 65 307 3.586e-05 0.0004726
354 CARDIAC MUSCLE CELL DIFFERENTIATION 23 74 3.671e-05 0.0004811
355 ACTIN MEDIATED CELL CONTRACTION 23 74 3.671e-05 0.0004811
356 STRIATED MUSCLE CONTRACTION 28 99 3.856e-05 0.0005008
357 POSITIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 13 30 3.864e-05 0.0005008
358 REGULATION OF HEART RATE BY CARDIAC CONDUCTION 13 30 3.864e-05 0.0005008
359 ION HOMEOSTASIS 108 576 3.854e-05 0.0005008
360 POST EMBRYONIC DEVELOPMENT 26 89 3.92e-05 0.0005067
361 REGULATION OF HEMOPOIESIS 66 314 3.972e-05 0.000512
362 RESPONSE TO DRUG 85 431 4.092e-05 0.0005259
363 ACTIVATION OF PROTEIN KINASE ACTIVITY 60 279 4.386e-05 0.0005621
364 POSITIVE REGULATION OF GROWTH 53 238 4.516e-05 0.0005773
365 SENSORY PERCEPTION OF PAIN 23 75 4.652e-05 0.000593
366 REGULATION OF PROTEIN SECRETION 78 389 4.675e-05 0.0005943
367 CELL FATE COMMITMENT 51 227 4.879e-05 0.0006185
368 RESPONSE TO CORTICOSTEROID 42 176 5.153e-05 0.0006515
369 POTASSIUM ION TRANSPORT 38 154 5.336e-05 0.0006728
370 NEGATIVE REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 21 66 5.374e-05 0.000674
371 NEGATIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 21 66 5.374e-05 0.000674
372 REGULATION OF AXON GUIDANCE 15 39 5.4e-05 0.0006755
373 RESPONSE TO KETONE 43 182 5.426e-05 0.0006768
374 POSITIVE REGULATION OF BINDING 33 127 5.457e-05 0.0006776
375 REGULATION OF CELL COMMUNICATION BY ELECTRICAL COUPLING 8 13 5.461e-05 0.0006776
376 CARDIAC VENTRICLE DEVELOPMENT 29 106 5.532e-05 0.0006845
377 CENTRAL NERVOUS SYSTEM NEURON AXONOGENESIS 12 27 5.671e-05 0.0006999
378 REGULATION OF EXTENT OF CELL GROWTH 28 101 5.712e-05 0.0007031
379 SECOND MESSENGER MEDIATED SIGNALING 39 160 5.727e-05 0.0007031
380 RESPIRATORY GASEOUS EXCHANGE 17 48 6.011e-05 0.0007322
381 CELLULAR RESPONSE TO EXTERNAL STIMULUS 57 264 5.984e-05 0.0007322
382 MYOFIBRIL ASSEMBLY 17 48 6.011e-05 0.0007322
383 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 40 166 6.102e-05 0.0007413
384 REGULATION OF LEUKOCYTE PROLIFERATION 47 206 6.351e-05 0.0007695
385 RESPONSE TO ESTROGEN 49 218 6.706e-05 0.0008063
386 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 49 218 6.706e-05 0.0008063
387 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 49 218 6.706e-05 0.0008063
388 EAR DEVELOPMENT 45 195 6.75e-05 0.0008094
389 MORPHOGENESIS OF A BRANCHING STRUCTURE 40 167 7.036e-05 0.0008416
390 GLAND MORPHOGENESIS 27 97 7.125e-05 0.0008479
391 REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 27 97 7.125e-05 0.0008479
392 REGULATION OF ACTIN FILAMENT LENGTH 38 156 7.188e-05 0.0008494
393 CELLULAR RESPONSE TO INORGANIC SUBSTANCE 38 156 7.188e-05 0.0008494
394 EYE DEVELOPMENT 67 326 7.192e-05 0.0008494
395 REGULATION OF SODIUM ION TRANSPORT 23 77 7.346e-05 0.0008653
396 POSITIVE REGULATION OF RESPONSE TO WOUNDING 39 162 7.655e-05 0.0008995
397 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 123 684 8.012e-05 0.000939
398 INOSITOL LIPID MEDIATED SIGNALING 32 124 8.101e-05 0.000947
399 RESPONSE TO ESTRADIOL 36 146 8.413e-05 0.0009811
400 RESPONSE TO REACTIVE OXYGEN SPECIES 44 191 8.439e-05 0.0009816
401 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 27 98 8.636e-05 0.001002
402 ORGAN GROWTH 21 68 8.755e-05 0.001013
403 PROTEIN OLIGOMERIZATION 84 434 8.933e-05 0.00103
404 REGULATION OF ERK1 AND ERK2 CASCADE 52 238 8.947e-05 0.00103
405 REGULATION OF STEM CELL PROLIFERATION 25 88 9.066e-05 0.001042
406 NEGATIVE REGULATION OF CELL AGING 9 17 9.147e-05 0.001048
407 VENTRICULAR SEPTUM DEVELOPMENT 18 54 9.176e-05 0.001049
408 SPROUTING ANGIOGENESIS 16 45 9.331e-05 0.001064
409 KIDNEY EPITHELIUM DEVELOPMENT 32 125 9.555e-05 0.001087
410 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 110 602 9.788e-05 0.001111
411 LIPID PHOSPHORYLATION 27 99 0.0001043 0.001179
412 HOMOPHILIC CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 37 153 0.0001044 0.001179
413 PROSTATE GLAND DEVELOPMENT 15 41 0.0001058 0.001192
414 CELLULAR HOMEOSTASIS 121 676 0.0001116 0.001254
415 CELL COMMUNICATION INVOLVED IN CARDIAC CONDUCTION 14 37 0.0001175 0.001314
416 REGULATION OF MUSCLE HYPERTROPHY 14 37 0.0001175 0.001314
417 CEREBRAL CORTEX DEVELOPMENT 28 105 0.0001199 0.001335
418 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 75 381 0.0001199 0.001335
419 REGULATION OF CELLULAR RESPONSE TO STRESS 123 691 0.0001252 0.00139
420 EMBRYONIC EYE MORPHOGENESIS 13 33 0.0001269 0.001406
421 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 30 116 0.0001278 0.001412
422 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 19 60 0.0001291 0.001423
423 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL BY SARCOPLASMIC RETICULUM 11 25 0.0001296 0.001426
424 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 26 95 0.0001305 0.001432
425 REGULATION OF MYELOID CELL DIFFERENTIATION 42 183 0.0001319 0.001441
426 NEGATIVE REGULATION OF ION TRANSPORT 32 127 0.0001319 0.001441
427 ENDOTHELIUM DEVELOPMENT 25 90 0.0001347 0.001468
428 PALATE DEVELOPMENT 24 85 0.000138 0.001501
429 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 21 70 0.000139 0.001504
430 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 21 70 0.000139 0.001504
431 ARTERY DEVELOPMENT 22 75 0.0001405 0.001517
432 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 31 122 0.0001413 0.001522
433 REGULATION OF FAT CELL DIFFERENTIATION 28 106 0.0001431 0.001538
434 PROTEIN COMPLEX SUBUNIT ORGANIZATION 245 1527 0.0001445 0.001549
435 POSITIVE REGULATION OF MAP KINASE ACTIVITY 46 207 0.0001463 0.001565
436 BONE DEVELOPMENT 37 156 0.0001597 0.001701
437 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 37 156 0.0001597 0.001701
438 MEMBRANE DEPOLARIZATION 19 61 0.000165 0.001752
439 REGULATION OF CARDIAC MUSCLE CONTRACTION 20 66 0.0001708 0.00181
440 REGULATION OF LEUKOCYTE DIFFERENTIATION 50 232 0.0001722 0.001821
441 LYMPHOCYTE ACTIVATION 68 342 0.0001795 0.001894
442 REGULATION OF CALCIUM ION TRANSPORT 46 209 0.0001851 0.001944
443 REGULATION OF PEPTIDE SECRETION 46 209 0.0001851 0.001944
444 PATTERN SPECIFICATION PROCESS 80 418 0.0001892 0.001983
445 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 35 146 0.00019 0.001986
446 MEMBRANE BIOGENESIS 12 30 0.000194 0.002015
447 SMOOTH MUSCLE CELL DIFFERENTIATION 12 30 0.000194 0.002015
448 REGULATION OF MEMBRANE REPOLARIZATION 12 30 0.000194 0.002015
449 REGULATION OF NEURON APOPTOTIC PROCESS 43 192 0.0001973 0.002045
450 MORPHOGENESIS OF AN EPITHELIAL FOLD 8 15 0.0002145 0.002208
451 REGULATION OF BMP SIGNALING PATHWAY 22 77 0.000214 0.002208
452 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 20 67 0.0002142 0.002208
453 COLUMNAR CUBOIDAL EPITHELIAL CELL DEVELOPMENT 16 48 0.0002224 0.002274
454 REGULATION OF ACTIN FILAMENT DEPOLYMERIZATION 16 48 0.0002224 0.002274
455 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORT 16 48 0.0002224 0.002274
456 MEMORY 26 98 0.0002256 0.002297
457 GLANDULAR EPITHELIAL CELL DIFFERENTIATION 14 39 0.0002256 0.002297
458 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 44 199 0.0002267 0.002303
459 ION TRANSMEMBRANE TRANSPORT 141 822 0.0002372 0.002404
460 RESPONSE TO HYDROGEN PEROXIDE 28 109 0.0002386 0.002413
461 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 17 53 0.0002421 0.002444
462 POSITIVE REGULATION OF CHEMOTAXIS 30 120 0.0002441 0.002459
463 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 64 321 0.0002527 0.00254
464 PROTEOGLYCAN BIOSYNTHETIC PROCESS 18 58 0.0002557 0.002564
465 NEGATIVE REGULATION OF ACTIN FILAMENT POLYMERIZATION 15 44 0.0002624 0.002626
466 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 7 12 0.000263 0.002627
467 REGULATION OF MUSCLE ADAPTATION 19 63 0.0002637 0.002628
468 NEGATIVE REGULATION OF GROWTH 50 236 0.0002653 0.002638
469 POSITIVE REGULATION OF PROTEIN BINDING 21 73 0.0002661 0.00264
470 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 20 68 0.0002669 0.002643
471 REGULATION OF NON CANONICAL WNT SIGNALING PATHWAY 9 19 0.0002724 0.002685
472 REGULATION OF CARDIAC MUSCLE CONTRACTION BY REGULATION OF THE RELEASE OF SEQUESTERED CALCIUM ION 9 19 0.0002724 0.002685
473 RAS PROTEIN SIGNAL TRANSDUCTION 34 143 0.0002747 0.002702
474 PROTEIN COMPLEX BIOGENESIS 186 1132 0.0002766 0.00271
475 PROTEIN COMPLEX ASSEMBLY 186 1132 0.0002766 0.00271
476 MYELOID CELL DIFFERENTIATION 42 189 0.0002774 0.002712
477 NEURON MIGRATION 28 110 0.0002811 0.002742
478 TRANSMEMBRANE TRANSPORT 181 1098 0.0002824 0.002749
479 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 30 121 0.000285 0.002769
480 REGULATION OF WNT SIGNALING PATHWAY 62 310 0.0002866 0.002772
481 SKELETAL SYSTEM MORPHOGENESIS 44 201 0.0002861 0.002772
482 NEURAL TUBE DEVELOPMENT 35 149 0.0002884 0.002784
483 LEUKOCYTE CELL CELL ADHESION 53 255 0.0002913 0.002806
484 RESPONSE TO INCREASED OXYGEN LEVELS 10 23 0.0002967 0.002826
485 REGULATION OF CARDIAC MUSCLE CONTRACTION BY CALCIUM ION SIGNALING 10 23 0.0002967 0.002826
486 NEGATIVE REGULATION OF LYMPHOCYTE APOPTOTIC PROCESS 11 27 0.000296 0.002826
487 POSITIVE REGULATION OF CELL CELL ADHESION 51 243 0.0002941 0.002826
488 EPITHELIAL CELL PROLIFERATION 24 89 0.000297 0.002826
489 RESPONSE TO HYPEROXIA 10 23 0.0002967 0.002826
490 SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR 31 127 0.0003065 0.002907
491 CELLULAR RESPONSE TO OXIDATIVE STRESS 41 184 0.0003067 0.002907
492 HEMOSTASIS 62 311 0.0003136 0.002966
493 DENDRITE DEVELOPMENT 22 79 0.0003194 0.003008
494 REGULATION OF HORMONE SECRETION 54 262 0.0003193 0.003008
495 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 32 133 0.0003264 0.003065
496 HOMEOSTATIC PROCESS 215 1337 0.0003268 0.003065
497 CANONICAL WNT SIGNALING PATHWAY 25 95 0.000338 0.003164
498 REGULATION OF RESPONSE TO WOUNDING 78 413 0.0003457 0.00323
499 OLFACTORY LOBE DEVELOPMENT 13 36 0.0003514 0.003276
500 COGNITION 52 251 0.0003584 0.003336
501 INORGANIC ION TRANSMEMBRANE TRANSPORT 104 583 0.0003727 0.003461
502 PROTEIN LOCALIZATION TO MEMBRANE 72 376 0.0003794 0.003517
503 T CELL DIFFERENTIATION 30 123 0.0003855 0.003566
504 AGING 54 264 0.0003881 0.003576
505 INSULIN RECEPTOR SIGNALING PATHWAY 22 80 0.0003874 0.003576
506 NEGATIVE REGULATION OF POTASSIUM ION TRANSPORT 12 32 0.000395 0.003632
507 CELL CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 44 204 0.0004016 0.003686
508 LIPID MODIFICATION 45 210 0.0004037 0.003698
509 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 31 129 0.0004104 0.003744
510 REGULATION OF POTASSIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 14 41 0.0004098 0.003744
511 AMINOGLYCAN BIOSYNTHETIC PROCESS 27 107 0.0004157 0.003785
512 RESPONSE TO GONADOTROPIN 11 28 0.0004309 0.003908
513 POSITIVE REGULATION OF PHOSPHATASE ACTIVITY 11 28 0.0004309 0.003908
514 REGULATION OF CELL CYCLE PHASE TRANSITION 63 321 0.0004367 0.003953
515 NEGATIVE REGULATION OF CELL ACTIVATION 36 158 0.0004443 0.004014
516 POSITIVE REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 10 24 0.0004499 0.004033
517 BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 10 24 0.0004499 0.004033
518 EMBRYONIC CAMERA TYPE EYE MORPHOGENESIS 10 24 0.0004499 0.004033
519 POSITIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 10 24 0.0004499 0.004033
520 PEPTIDYL THREONINE MODIFICATION 15 46 0.0004539 0.004061
521 REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 27 108 0.000487 0.004349
522 TRANSCRIPTION INITIATION FROM RNA POLYMERASE II PROMOTER 35 153 0.0004894 0.004363
523 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 49 236 0.0004946 0.0044
524 HEART MORPHOGENESIS 45 212 0.000501 0.004449
525 REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 24 92 0.0005055 0.004481
526 STEROID HORMONE MEDIATED SIGNALING PATHWAY 30 125 0.0005161 0.004565
527 REGULATION OF CIRCADIAN RHYTHM 26 103 0.0005237 0.004623
528 POSITIVE REGULATION OF CELL GROWTH 34 148 0.0005388 0.004748
529 IN UTERO EMBRYONIC DEVELOPMENT 61 311 0.000542 0.004767
530 PROTEIN STABILIZATION 31 131 0.0005443 0.00477
531 RETINA DEVELOPMENT IN CAMERA TYPE EYE 31 131 0.0005443 0.00477
532 NEURON RECOGNITION 12 33 0.0005481 0.004794
533 DIVALENT INORGANIC CATION TRANSPORT 54 268 0.0005667 0.004947
534 CIRCADIAN RHYTHM 32 137 0.0005699 0.004965
535 POSITIVE REGULATION OF BLOOD CIRCULATION 24 93 0.0005991 0.00521
536 ENDOTHELIAL CELL DIFFERENTIATION 20 72 0.0006082 0.00527
537 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 48 232 0.0006088 0.00527
538 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 40 184 0.0006094 0.00527
539 RESPONSE TO CALCIUM ION 28 115 0.0006107 0.005272
540 POSITIVE REGULATION OF PROTEIN IMPORT 26 104 0.0006136 0.005287
541 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 19 67 0.0006236 0.005363
542 POSITIVE REGULATION OF PROTEIN CATABOLIC PROCESS 53 263 0.0006315 0.005392
543 CYCLIC NUCLEOTIDE METABOLIC PROCESS 17 57 0.0006299 0.005392
544 CIRCADIAN REGULATION OF GENE EXPRESSION 17 57 0.0006299 0.005392
545 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 18 62 0.0006315 0.005392
546 MEMBRANE RAFT ORGANIZATION 8 17 0.0006372 0.00542
547 INTESTINAL EPITHELIAL CELL DIFFERENTIATION 8 17 0.0006372 0.00542
548 REGULATION OF ACTION POTENTIAL 13 38 0.0006414 0.005436
549 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 13 38 0.0006414 0.005436
550 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 70 370 0.0006429 0.005439
551 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 25 99 0.0006599 0.005573
552 POSITIVE REGULATION OF DEFENSE RESPONSE 69 364 0.000662 0.00558
553 ORGAN REGENERATION 22 83 0.000673 0.005642
554 PROTEOGLYCAN METABOLIC PROCESS 22 83 0.000673 0.005642
555 MODULATION OF SYNAPTIC TRANSMISSION 59 301 0.0006729 0.005642
556 CHONDROCYTE DEVELOPMENT 9 21 0.0006797 0.005678
557 NEGATIVE REGULATION OF POTASSIUM ION TRANSMEMBRANE TRANSPORT 9 21 0.0006797 0.005678
558 LYMPHOCYTE DIFFERENTIATION 44 209 0.0006884 0.00574
559 NEGATIVE REGULATION OF STEM CELL DIFFERENTIATION 14 43 0.0007093 0.005862
560 NEGATIVE REGULATION OF LEUKOCYTE APOPTOTIC PROCESS 14 43 0.0007093 0.005862
561 RESPONSE TO BMP 24 94 0.0007073 0.005862
562 CEREBRAL CORTEX CELL MIGRATION 14 43 0.0007093 0.005862
563 CELLULAR RESPONSE TO BMP STIMULUS 24 94 0.0007073 0.005862
564 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 69 365 0.0007151 0.0059
565 REGULATION OF BINDING 56 283 0.0007172 0.005907
566 SINGLE ORGANISM CELLULAR LOCALIZATION 149 898 0.0007202 0.005921
567 NEGATIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 36 162 0.0007281 0.005975
568 HIPPOCAMPUS DEVELOPMENT 20 73 0.0007372 0.006039
569 REGULATION OF CELL SHAPE 32 139 0.0007431 0.006077
570 POSITIVE REGULATION OF SODIUM ION TRANSPORT 12 34 0.0007483 0.006108
571 SECRETION 103 588 0.0007606 0.006198
572 REGULATION OF CARTILAGE DEVELOPMENT 18 63 0.0007786 0.006323
573 NEGATIVE REGULATION OF EPITHELIAL CELL MIGRATION 16 53 0.0007778 0.006323
574 ENDOCYTOSIS 91 509 0.0007801 0.006324
575 MAMMARY GLAND DEVELOPMENT 28 117 0.000817 0.006611
576 SEX DIFFERENTIATION 53 266 0.000831 0.006713
577 FAT CELL DIFFERENTIATION 26 106 0.0008348 0.006732
578 POSITIVE REGULATION OF IMMUNE RESPONSE 99 563 0.0008363 0.006732
579 REGULATION OF LEUKOCYTE APOPTOTIC PROCESS 21 79 0.0008474 0.006778
580 REGULATION OF PHOSPHOLIPASE C ACTIVITY 13 39 0.0008493 0.006778
581 ERBB2 SIGNALING PATHWAY 13 39 0.0008493 0.006778
582 REGULATION OF STRIATED MUSCLE CONTRACTION 21 79 0.0008474 0.006778
583 NUCLEOBASE METABOLIC PROCESS 13 39 0.0008493 0.006778
584 POSITIVE REGULATION OF SMOOTH MUSCLE CONTRACTION 11 30 0.0008565 0.006824
585 MONOVALENT INORGANIC CATION HOMEOSTASIS 29 123 0.00086 0.00684
586 PROTEIN HOMOOLIGOMERIZATION 50 248 0.0008745 0.006944
587 CELL CELL JUNCTION ASSEMBLY 20 74 0.0008892 0.007049
588 POSITIVE REGULATION OF ION TRANSPORT 48 236 0.0008998 0.007108
589 POSITIVE REGULATION OF CELL SIZE 7 14 0.0008995 0.007108
590 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 31 135 0.0009319 0.007349
591 DIVALENT INORGANIC CATION HOMEOSTASIS 65 343 0.0009389 0.007392
592 REGULATION OF PROTEIN ACETYLATION 18 64 0.0009542 0.007487
593 RESPONSE TO CORTICOSTERONE 10 26 0.0009539 0.007487
594 REGULATION OF LYMPHOCYTE APOPTOTIC PROCESS 16 54 0.0009743 0.007617
595 CELLULAR MONOVALENT INORGANIC CATION HOMEOSTASIS 24 96 0.0009756 0.007617
596 ALPHA BETA T CELL ACTIVATION 16 54 0.0009743 0.007617
597 NEGATIVE REGULATION OF HOMEOSTATIC PROCESS 29 124 0.0009862 0.007686
598 NEGATIVE REGULATION OF ACTIN FILAMENT DEPOLYMERIZATION 12 35 0.001006 0.007803
599 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 34 153 0.001006 0.007803
600 EMBRYONIC CAMERA TYPE EYE DEVELOPMENT 12 35 0.001006 0.007803
601 NEGATIVE REGULATION OF VASCULATURE DEVELOPMENT 21 80 0.001011 0.007828
602 NEGATIVE REGULATION OF MUSCLE CONTRACTION 9 22 0.001019 0.007851
603 RETINA LAYER FORMATION 9 22 0.001019 0.007851
604 NUCLEOBASE BIOSYNTHETIC PROCESS 8 18 0.001017 0.007851
605 POSITIVE REGULATION OF INFLAMMATORY RESPONSE 27 113 0.001029 0.007911
606 POSITIVE REGULATION OF CYTOKINE PRODUCTION 69 370 0.001043 0.008006
607 REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 20 75 0.001067 0.008182
608 DIGESTIVE SYSTEM DEVELOPMENT 33 148 0.001114 0.008496
609 REGULATION OF PROTEIN TARGETING 59 307 0.001111 0.008496
610 MALE SEX DIFFERENTIATION 33 148 0.001114 0.008496
611 CELL CYCLE ARREST 34 154 0.001134 0.008634
612 RESPONSE TO METAL ION 63 333 0.001163 0.00884
613 POSITIVE REGULATION OF ERK1 AND ERK2 CASCADE 37 172 0.001169 0.008859
614 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 30 131 0.001169 0.008859
615 MITOTIC CYTOKINESIS 11 31 0.001174 0.008882
616 REGULATION OF ADHERENS JUNCTION ORGANIZATION 15 50 0.001207 0.009018
617 REGULATION OF POSTSYNAPTIC MEMBRANE POTENTIAL 16 55 0.001211 0.009018
618 INTESTINAL EPITHELIAL CELL DEVELOPMENT 6 11 0.001204 0.009018
619 CHONDROCYTE DIFFERENTIATION 17 60 0.001195 0.009018
620 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 15 50 0.001207 0.009018
621 SKELETAL MUSCLE ORGAN DEVELOPMENT 31 137 0.001204 0.009018
622 CRANIAL SKELETAL SYSTEM DEVELOPMENT 16 55 0.001211 0.009018
623 RESPONSE TO PROGESTERONE 15 50 0.001207 0.009018
624 REGULATION OF B CELL PROLIFERATION 16 55 0.001211 0.009018
625 POSITIVE REGULATION OF MYELOID LEUKOCYTE CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 6 11 0.001204 0.009018
626 REGULATION OF MUSCLE TISSUE DEVELOPMENT 25 103 0.001222 0.009083
627 POSITIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 51 258 0.001235 0.009163
628 REGULATION OF CYTOKINE PRODUCTION 98 563 0.001241 0.009181
629 REGULATION OF DENDRITE DEVELOPMENT 28 120 0.00124 0.009181
630 PEPTIDYL AMINO ACID MODIFICATION 139 841 0.001251 0.009242
631 POSITIVE REGULATION OF TRANSPORTER ACTIVITY 20 76 0.001275 0.009389
632 GASTRULATION 34 155 0.001275 0.009389
633 REGULATION OF WOUND HEALING 29 126 0.001288 0.00945
634 OSTEOBLAST DIFFERENTIATION 29 126 0.001288 0.00945
635 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 41 197 0.001296 0.00948
636 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 41 197 0.001296 0.00948
637 T CELL PROLIFERATION 12 36 0.001333 0.009693
638 POSITIVE REGULATION OF AXON EXTENSION 12 36 0.001333 0.009693
639 LAMELLIPODIUM ORGANIZATION 12 36 0.001333 0.009693
640 POSITIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 12 36 0.001333 0.009693
641 VESICLE MEDIATED TRANSPORT 196 1239 0.001344 0.009755
NumGOOverlapSizeP ValueAdj. P Value
1 ENZYME BINDING 351 1737 3.683e-19 3.421e-16
2 ACTIN BINDING 105 393 1.197e-13 5.561e-11
3 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 147 629 2.52e-13 7.802e-11
4 PROTEIN DOMAIN SPECIFIC BINDING 141 624 1.105e-11 2.567e-09
5 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 85 315 1.487e-11 2.763e-09
6 CYTOSKELETAL PROTEIN BINDING 171 819 6.863e-11 1.063e-08
7 KINASE BINDING 135 606 8.614e-11 1.143e-08
8 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 231 1199 1.158e-10 1.27e-08
9 MACROMOLECULAR COMPLEX BINDING 262 1399 1.23e-10 1.27e-08
10 PROTEIN COMPLEX BINDING 183 935 3.262e-09 3.031e-07
11 IDENTICAL PROTEIN BINDING 225 1209 4.952e-09 4.183e-07
12 PROTEIN KINASE ACTIVITY 134 640 6.957e-09 4.972e-07
13 REGULATORY REGION NUCLEIC ACID BINDING 163 818 6.737e-09 4.972e-07
14 PHOSPHATIDYLINOSITOL BINDING 56 200 1.038e-08 6.428e-07
15 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 80 328 9.896e-09 6.428e-07
16 RIBONUCLEOTIDE BINDING 320 1860 1.737e-08 1.009e-06
17 MOLECULAR FUNCTION REGULATOR 244 1353 1.948e-08 1.065e-06
18 RECEPTOR BINDING 262 1476 2.472e-08 1.276e-06
19 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 59 226 6.767e-08 3.309e-06
20 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 73 303 7.367e-08 3.422e-06
21 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 59 228 9.458e-08 4.184e-06
22 SMAD BINDING 27 72 1.184e-07 4.999e-06
23 PROTEIN DIMERIZATION ACTIVITY 207 1149 2.699e-07 1.09e-05
24 KINASE ACTIVITY 159 842 3.904e-07 1.511e-05
25 PHOSPHOLIPID BINDING 80 360 6.619e-07 2.46e-05
26 CYTOKINE BINDING 30 92 8.297e-07 2.965e-05
27 PROTEIN HOMODIMERIZATION ACTIVITY 138 722 1.166e-06 4.011e-05
28 TRANSCRIPTION FACTOR BINDING 106 524 1.459e-06 4.839e-05
29 METAL ION TRANSMEMBRANE TRANSPORTER ACTIVITY 88 417 1.896e-06 6.074e-05
30 PROTEIN SERINE THREONINE KINASE ACTIVITY 92 445 2.778e-06 8.603e-05
31 ADENYL NUCLEOTIDE BINDING 254 1514 4.522e-06 0.0001355
32 LIPID BINDING 125 657 4.684e-06 0.000136
33 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 176 992 5.702e-06 0.0001605
34 CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 118 622 9.875e-06 0.0002621
35 INORGANIC CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 103 527 9.864e-06 0.0002621
36 TRANSMEMBRANE TRANSPORTER ACTIVITY 175 997 1.157e-05 0.0002986
37 SEQUENCE SPECIFIC DNA BINDING 180 1037 1.699e-05 0.0004265
38 GTPASE BINDING 64 295 1.866e-05 0.0004562
39 ION CHANNEL BINDING 31 111 2.003e-05 0.000477
40 CATION CHANNEL ACTIVITY 64 298 2.597e-05 0.0006031
41 CORE PROMOTER PROXIMAL REGION DNA BINDING 76 371 2.747e-05 0.0006224
42 STEROID HORMONE RECEPTOR ACTIVITY 20 59 2.884e-05 0.000638
43 DOUBLE STRANDED DNA BINDING 137 764 3.685e-05 0.0007962
44 COLLAGEN BINDING 21 65 4.168e-05 0.00088
45 CELL ADHESION MOLECULE BINDING 44 186 4.331e-05 0.0008942
46 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 22 70 4.45e-05 0.0008987
47 TRANSFORMING GROWTH FACTOR BETA BINDING 9 16 4.864e-05 0.0009613
48 GLYCOSAMINOGLYCAN BINDING 47 205 5.592e-05 0.001082
49 GLYCOPROTEIN BINDING 28 101 5.712e-05 0.001083
50 TRANSLATION REPRESSOR ACTIVITY 10 20 6.929e-05 0.001287
51 VOLTAGE GATED ION CHANNEL ACTIVITY 44 190 7.408e-05 0.001349
52 CORE PROMOTER BINDING 37 152 9.024e-05 0.001601
53 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 108 588 9.135e-05 0.001601
54 POTASSIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 35 143 0.0001228 0.002112
55 SH3 DOMAIN BINDING 30 116 0.0001278 0.002159
56 PDZ DOMAIN BINDING 25 90 0.0001347 0.002235
57 PHOSPHATIDYLINOSITOL 4 5 BISPHOSPHATE BINDING 17 51 0.0001427 0.002327
58 GROWTH FACTOR RECEPTOR BINDING 32 129 0.0001802 0.002886
59 HEPARIN BINDING 37 157 0.0001834 0.002887
60 TRANSPORTER ACTIVITY 207 1276 0.0002605 0.004033
61 MONOVALENT INORGANIC CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 71 366 0.0002813 0.004271
62 ACTIN FILAMENT BINDING 30 121 0.000285 0.004271
63 SULFUR COMPOUND BINDING 49 234 0.0004035 0.00595
64 VOLTAGE GATED SODIUM CHANNEL ACTIVITY 9 20 0.0004385 0.006366
65 PASSIVE TRANSMEMBRANE TRANSPORTER ACTIVITY 85 464 0.0005311 0.00759
66 POTASSIUM CHANNEL ACTIVITY 29 120 0.0005619 0.007909
67 RECEPTOR SIGNALING PROTEIN ACTIVITY 38 172 0.0005941 0.008237
68 TRANSMEMBRANE RECEPTOR PROTEIN PHOSPHATASE ACTIVITY 8 17 0.0006372 0.008579
69 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE ACTIVITY 8 17 0.0006372 0.008579
70 CALMODULIN BINDING 39 179 0.0006761 0.008973
71 PROTEIN HETERODIMERIZATION ACTIVITY 85 468 0.0006984 0.009001
72 PHOSPHATIDYLINOSITOL PHOSPHATE BINDING 28 116 0.0007073 0.009001
73 UBIQUITIN LIKE PROTEIN LIGASE BINDING 53 264 0.0006927 0.009001
74 CYTOKINE RECEPTOR ACTIVITY 23 89 0.000755 0.009478
NumGOOverlapSizeP ValueAdj. P Value
1 CELL JUNCTION 262 1151 2.387e-21 1.394e-18
2 MEMBRANE REGION 237 1134 9.554e-15 2.79e-12
3 CELL PROJECTION 333 1786 4.521e-13 8.801e-11
4 NEURON PART 248 1265 3.457e-12 5.048e-10
5 SYNAPSE 163 754 1.16e-11 1.355e-09
6 VACUOLE 230 1180 4.057e-11 2.633e-09
7 INTRINSIC COMPONENT OF PLASMA MEMBRANE 303 1649 3.47e-11 2.633e-09
8 NEURON PROJECTION 192 942 3.94e-11 2.633e-09
9 MEMBRANE MICRODOMAIN 79 288 3.226e-11 2.633e-09
10 ENDOSOME 167 793 5.748e-11 3.357e-09
11 CELL LEADING EDGE 90 350 6.372e-11 3.383e-09
12 ANCHORING JUNCTION 115 489 6.991e-11 3.402e-09
13 CELL SUBSTRATE JUNCTION 98 398 1.263e-10 5.674e-09
14 CELL CELL JUNCTION 94 383 3.623e-10 1.511e-08
15 PLASMA MEMBRANE REGION 185 929 6.509e-10 2.534e-08
16 GOLGI APPARATUS 261 1445 5.1e-09 1.862e-07
17 CELL SURFACE 153 757 7.431e-09 2.411e-07
18 SARCOLEMMA 41 125 7.177e-09 2.411e-07
19 INTRACELLULAR VESICLE 231 1259 1.083e-08 3.329e-07
20 EXCITATORY SYNAPSE 55 197 1.564e-08 4.568e-07
21 PLASMA MEMBRANE PROTEIN COMPLEX 110 510 3.092e-08 8.598e-07
22 T TUBULE 21 45 3.446e-08 9.147e-07
23 VESICLE MEMBRANE 110 512 3.844e-08 9.76e-07
24 POSTSYNAPSE 87 378 4.158e-08 1.012e-06
25 SYNAPSE PART 126 610 4.46e-08 1.042e-06
26 SOMATODENDRITIC COMPARTMENT 130 650 1.884e-07 4.232e-06
27 RUFFLE 44 156 3.02e-07 6.533e-06
28 CYTOPLASMIC VESICLE PART 121 601 3.476e-07 7.251e-06
29 ACTIN CYTOSKELETON 94 444 7.378e-07 1.486e-05
30 CONTRACTILE FIBER 53 211 1.127e-06 2.194e-05
31 ACTOMYOSIN 23 62 1.258e-06 2.37e-05
32 CORTICAL ACTIN CYTOSKELETON 22 58 1.377e-06 2.513e-05
33 GOLGI APPARATUS PART 164 893 1.519e-06 2.688e-05
34 CELL PROJECTION PART 172 946 1.603e-06 2.753e-05
35 CYTOPLASMIC REGION 66 287 1.78e-06 2.97e-05
36 GOLGI MEMBRANE 134 703 1.935e-06 3.117e-05
37 PLASMA MEMBRANE RAFT 28 86 1.975e-06 3.117e-05
38 ENDOCYTIC VESICLE 60 256 2.706e-06 4.123e-05
39 DENDRITE 93 451 2.754e-06 4.123e-05
40 AXON PART 53 219 3.738e-06 5.457e-05
41 CORTICAL CYTOSKELETON 26 81 6.085e-06 8.667e-05
42 CLATHRIN COATED VESICLE 41 157 6.381e-06 8.872e-05
43 AXON 86 418 7.063e-06 9.592e-05
44 EARLY ENDOSOME 66 301 9.687e-06 0.0001286
45 APICAL JUNCTION COMPLEX 35 128 1.004e-05 0.0001303
46 CELL CORTEX 55 238 1.073e-05 0.0001363
47 LAMELLIPODIUM 43 172 1.263e-05 0.0001569
48 ACTIN FILAMENT BUNDLE 20 57 1.616e-05 0.0001966
49 VACUOLAR PART 128 694 1.735e-05 0.0002068
50 APICAL PART OF CELL 75 361 1.874e-05 0.0002158
51 NEURON SPINE 33 121 1.885e-05 0.0002158
52 CELL CELL CONTACT ZONE 21 64 3.21e-05 0.0003471
53 CYTOSKELETON 313 1967 3.159e-05 0.0003471
54 PIGMENT GRANULE 29 103 3.101e-05 0.0003471
55 CELL CORTEX PART 32 119 3.4e-05 0.0003611
56 PROTEINACEOUS EXTRACELLULAR MATRIX 73 356 3.786e-05 0.0003948
57 INTERCALATED DISC 18 51 3.876e-05 0.0003972
58 CLATHRIN COATED ENDOCYTIC VESICLE 21 65 4.168e-05 0.0004169
59 LYTIC VACUOLE 100 526 4.212e-05 0.0004169
60 ACTIN FILAMENT 22 70 4.45e-05 0.0004331
61 COATED VESICLE 52 234 5.62e-05 0.000538
62 CLATHRIN COATED VESICLE MEMBRANE 24 81 5.967e-05 0.0005532
63 EXTRINSIC COMPONENT OF MEMBRANE 55 252 5.876e-05 0.0005532
64 CATION CHANNEL COMPLEX 40 167 7.036e-05 0.0006421
65 LATE ENDOSOME 48 213 7.397e-05 0.0006646
66 VACUOLAR MEMBRANE 108 587 8.519e-05 0.0007538
67 SIDE OF MEMBRANE 83 428 9.158e-05 0.0007875
68 APICAL PLASMA MEMBRANE 61 292 9.169e-05 0.0007875
69 FILOPODIUM 26 94 0.0001079 0.0009001
70 ENDOSOMAL PART 83 430 0.0001079 0.0009001
71 TRANSFERASE COMPLEX 125 703 0.0001161 0.0009546
72 MEMBRANE PROTEIN COMPLEX 172 1020 0.0001266 0.001026
73 COATED VESICLE MEMBRANE 34 139 0.0001543 0.001234
74 PERINUCLEAR REGION OF CYTOPLASM 115 642 0.0001585 0.001251
75 I BAND 30 121 0.000285 0.002188
76 SITE OF POLARIZED GROWTH 35 149 0.0002884 0.002188
77 CELL BODY 91 494 0.0002846 0.002188
78 LATERAL PLASMA MEMBRANE 16 50 0.0003769 0.002788
79 TRANSPORT VESICLE MEMBRANE 35 151 0.0003772 0.002788
80 AXONAL GROWTH CONE 9 20 0.0004385 0.003201
81 BASOLATERAL PLASMA MEMBRANE 45 211 0.00045 0.003245
82 PML BODY 25 97 0.0004756 0.003387
83 TRANSCRIPTION FACTOR COMPLEX 59 298 0.0005182 0.003646
84 SECRETORY GRANULE MEMBRANE 21 78 0.000707 0.004915
85 CLATHRIN COATED ENDOCYTIC VESICLE MEMBRANE 15 48 0.0007538 0.005179
86 EXTRACELLULAR MATRIX 78 426 0.000892 0.005969
87 VOLTAGE GATED SODIUM CHANNEL COMPLEX 7 14 0.0008995 0.005969
88 ENDOPLASMIC RETICULUM 253 1631 0.0008929 0.005969
89 EARLY ENDOSOME MEMBRANE 27 113 0.001029 0.006749
90 CYCLIN DEPENDENT PROTEIN KINASE HOLOENZYME COMPLEX 11 31 0.001174 0.007617
91 MYELIN SHEATH 36 168 0.001452 0.009317
92 COSTAMERE 8 19 0.001559 0.009898

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Focal_adhesion_hsa04510 57 199 3.097e-09 1.61e-07
2 Cellular_senescence_hsa04218 47 160 3.089e-08 8.032e-07
3 Regulation_of_actin_cytoskeleton_hsa04810 54 208 2.905e-07 5.036e-06
4 Hippo_signaling_pathway_hsa04390 43 154 5.548e-07 7.212e-06
5 MAPK_signaling_pathway_hsa04010 68 295 1.143e-06 1.188e-05
6 Rap1_signaling_pathway_hsa04015 51 206 2.807e-06 2.433e-05
7 TGF_beta_signaling_pathway_hsa04350 27 84 3.942e-06 2.928e-05
8 Cell_adhesion_molecules_.CAMs._hsa04514 38 145 1.254e-05 8.151e-05
9 FoxO_signaling_pathway_hsa04068 35 132 2.072e-05 0.0001124
10 Ras_signaling_pathway_hsa04014 53 232 2.162e-05 0.0001124
11 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 36 139 2.764e-05 0.0001307
12 PI3K_Akt_signaling_pathway_hsa04151 72 352 4.638e-05 0.000193
13 Apelin_signaling_pathway_hsa04371 35 137 4.825e-05 0.000193
14 Cell_cycle_hsa04110 32 124 8.101e-05 0.0002917
15 Wnt_signaling_pathway_hsa04310 36 146 8.413e-05 0.0002917
16 Calcium_signaling_pathway_hsa04020 42 182 0.0001159 0.0003767
17 cGMP_PKG_signaling_pathway_hsa04022 37 163 0.0004031 0.001233
18 ECM_receptor_interaction_hsa04512 22 82 0.0005623 0.001624
19 cAMP_signaling_pathway_hsa04024 42 198 0.0007666 0.002098
20 Adherens_junction_hsa04520 19 72 0.001609 0.004184
21 Tight_junction_hsa04530 36 170 0.001804 0.004432
22 Hedgehog_signaling_pathway_hsa04340 14 47 0.001875 0.004432
23 p53_signaling_pathway_hsa04115 18 68 0.002032 0.004595
24 mTOR_signaling_pathway_hsa04150 32 151 0.003094 0.006703
25 Phagosome_hsa04145 32 152 0.003443 0.006896
26 Phospholipase_D_signaling_pathway_hsa04072 31 146 0.003448 0.006896
27 Gap_junction_hsa04540 21 88 0.003593 0.00692
28 HIF_1_signaling_pathway_hsa04066 23 100 0.003913 0.007266
29 ErbB_signaling_pathway_hsa04012 20 85 0.005235 0.009388
30 Oocyte_meiosis_hsa04114 26 124 0.008248 0.0143
31 Hippo_signaling_pathway_multiple_species_hsa04392 9 29 0.008841 0.01483
32 Sphingolipid_signaling_pathway_hsa04071 24 118 0.01561 0.02537
33 Endocytosis_hsa04144 42 244 0.03196 0.05036
34 Autophagy_animal_hsa04140 24 128 0.03832 0.05861
35 Apoptosis_hsa04210 25 138 0.0502 0.07458
36 Phosphatidylinositol_signaling_system_hsa04070 18 99 0.08395 0.1213
37 Jak_STAT_signaling_pathway_hsa04630 27 162 0.09938 0.1368
38 TNF_signaling_pathway_hsa04668 19 108 0.1 0.1368
39 Mitophagy_animal_hsa04137 12 65 0.1283 0.171
40 Ferroptosis_hsa04216 8 40 0.1376 0.1789
41 AMPK_signaling_pathway_hsa04152 19 121 0.2159 0.2729
42 ABC_transporters_hsa02010 8 45 0.2204 0.2729
43 VEGF_signaling_pathway_hsa04370 10 59 0.2273 0.2749
44 Lysosome_hsa04142 19 123 0.2378 0.2811
45 Cytokine_cytokine_receptor_interaction_hsa04060 39 270 0.2537 0.2932
46 Peroxisome_hsa04146 11 83 0.5152 0.5824
47 Necroptosis_hsa04217 20 164 0.6472 0.7161
48 Notch_signaling_pathway_hsa04330 5 48 0.7615 0.825
49 Neuroactive_ligand_receptor_interaction_hsa04080 32 278 0.7874 0.834
50 Autophagy_other_hsa04136 3 32 0.8019 0.834
51 Apoptosis_multiple_species_hsa04215 3 33 0.8188 0.8348
52 NF_kappa_B_signaling_pathway_hsa04064 9 95 0.881 0.881

Quest ID: 347b9f13f9a4c25fb4bee217d07b641d