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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-106b-5p AADAC 1.22 0 -4.47 0 MirTarget -0.47 0 NA
2 hsa-miR-93-5p AADAC 1.02 0 -4.47 0 MirTarget -0.44 1.0E-5 NA
3 hsa-miR-106b-5p ABCA1 1.22 0 -1.41 0 MirTarget; miRNATAP -0.35 0 NA
4 hsa-miR-93-5p ABCA1 1.02 0 -1.41 0 MirTarget; miRNATAP -0.36 0 NA
5 hsa-miR-106b-5p ABCD2 1.22 0 -4.13 0 MirTarget -0.54 0 NA
6 hsa-miR-93-5p ABCD2 1.02 0 -4.13 0 MirTarget -0.62 0 NA
7 hsa-miR-106b-5p ABHD2 1.22 0 0.45 0.00053 miRNATAP -0.3 0 NA
8 hsa-miR-93-5p ABHD2 1.02 0 0.45 0.00053 miRNATAP -0.29 0 NA
9 hsa-miR-106b-5p ABHD5 1.22 0 -0.76 0 MirTarget -0.11 0 NA
10 hsa-miR-93-5p ACER3 1.02 0 -0.64 0 mirMAP -0.12 0.00102 NA
11 hsa-miR-106b-5p ACOX1 1.22 0 -0.61 0 mirMAP -0.12 0 NA
12 hsa-miR-106b-5p ACSL4 1.22 0 -1.48 0 MirTarget; miRNATAP -0.18 0 NA
13 hsa-miR-93-5p ACSL4 1.02 0 -1.48 0 MirTarget; miRNATAP -0.23 0 NA
14 hsa-miR-106b-5p ACVR1B 1.22 0 0.15 0.02139 miRNATAP -0.1 0 NA
15 hsa-miR-106b-5p ADAM22 1.22 0 -1.22 0 MirTarget; mirMAP -0.51 0 NA
16 hsa-miR-93-5p ADAM22 1.02 0 -1.22 0 MirTarget; mirMAP -0.54 0 NA
17 hsa-miR-106b-5p ADAMTS5 1.22 0 -3.55 0 miRNATAP -0.71 0 NA
18 hsa-miR-20a-3p ADAMTS6 -0.22 0.17987 1.1 0 miRNATAP -0.13 0 NA
19 hsa-miR-106a-5p ADCY1 0.57 0.00015 -0.05 0.84149 mirMAP -0.21 0.00014 NA
20 hsa-miR-106b-5p ADCY1 1.22 0 -0.05 0.84149 mirMAP -0.46 0 NA
21 hsa-miR-20a-3p ADCY1 -0.22 0.17987 -0.05 0.84149 mirMAP -0.27 0 NA
22 hsa-miR-93-5p ADCY1 1.02 0 -0.05 0.84149 mirMAP -0.48 0 NA
23 hsa-miR-106b-5p ADCY9 1.22 0 0.12 0.23839 mirMAP -0.3 0 NA
24 hsa-miR-93-5p ADCY9 1.02 0 0.12 0.23839 mirMAP -0.26 0 NA
25 hsa-miR-106b-5p ADRA2A 1.22 0 -1.76 0 miRNATAP -0.78 0 NA
26 hsa-miR-106b-5p AFF4 1.22 0 -0.28 0.00153 miRNATAP -0.31 0 NA
27 hsa-miR-93-5p AFF4 1.02 0 -0.28 0.00153 miRNATAP -0.28 0 NA
28 hsa-miR-106b-5p AFP 1.22 0 -3.14 0 miRNAWalker2 validate -0.93 0 NA
29 hsa-miR-20a-3p AGFG2 -0.22 0.17987 -0.32 2.0E-5 mirMAP -0.12 0 NA
30 hsa-miR-106b-5p AGPS 1.22 0 -0.4 0.00019 mirMAP -0.18 0 NA
31 hsa-miR-93-5p AGPS 1.02 0 -0.4 0.00019 mirMAP -0.19 0 NA
32 hsa-miR-106a-5p AHNAK 0.57 0.00015 -1.77 0 miRNATAP -0.18 0 NA
33 hsa-miR-106b-5p AHNAK 1.22 0 -1.77 0 miRNATAP -0.67 0 NA
34 hsa-miR-93-5p AHNAK 1.02 0 -1.77 0 miRNATAP -0.58 0 NA
35 hsa-miR-106b-5p AKAP11 1.22 0 -0.85 0 miRNAWalker2 validate -0.35 0 NA
36 hsa-miR-93-5p AKAP11 1.02 0 -0.85 0 miRNAWalker2 validate -0.33 0 NA
37 hsa-miR-106b-5p AKAP13 1.22 0 -0.61 0 MirTarget; mirMAP; miRNATAP -0.23 0 NA
38 hsa-miR-93-5p AKAP13 1.02 0 -0.61 0 MirTarget; miRNATAP -0.26 0 NA
39 hsa-miR-106b-5p AKT3 1.22 0 -1.39 0 miRNATAP -0.33 0 NA
40 hsa-miR-93-5p AKT3 1.02 0 -1.39 0 miRNATAP -0.36 0 NA
41 hsa-miR-93-5p ALDH1A3 1.02 0 -2.22 0 mirMAP -0.4 0 NA
42 hsa-miR-106b-5p ALDH3A2 1.22 0 -0.86 0 mirMAP -0.3 0 NA
43 hsa-miR-106b-5p ALPK3 1.22 0 -1.48 0 mirMAP -0.31 0 NA
44 hsa-miR-106a-5p ALX4 0.57 0.00015 -3.22 0 miRNATAP -0.26 3.0E-5 NA
45 hsa-miR-106b-5p ALX4 1.22 0 -3.22 0 miRNATAP -0.65 0 NA
46 hsa-miR-93-5p ALX4 1.02 0 -3.22 0 miRNATAP -0.62 0 NA
47 hsa-miR-20a-3p ANGPTL1 -0.22 0.17987 -3.72 0 MirTarget -0.26 0 NA
48 hsa-miR-106a-5p ANK2 0.57 0.00015 -2.51 0 MirTarget; miRNATAP -0.17 1.0E-5 NA
49 hsa-miR-106b-5p ANK2 1.22 0 -2.51 0 MirTarget; miRNATAP -0.57 0 NA
50 hsa-miR-93-5p ANK2 1.02 0 -2.51 0 MirTarget; miRNATAP -0.6 0 NA
51 hsa-miR-106b-5p ANKFY1 1.22 0 -0.49 0 miRNAWalker2 validate; MirTarget -0.21 0 NA
52 hsa-miR-93-5p ANKFY1 1.02 0 -0.49 0 miRNAWalker2 validate -0.17 0 NA
53 hsa-miR-106b-5p ANKH 1.22 0 -0.31 0.00327 MirTarget -0.14 2.0E-5 NA
54 hsa-miR-93-5p ANKH 1.02 0 -0.31 0.00327 MirTarget -0.16 0 NA
55 hsa-miR-106b-5p ANKRD12 1.22 0 -0.64 0 MirTarget -0.24 0 NA
56 hsa-miR-93-5p ANKRD12 1.02 0 -0.64 0 MirTarget -0.3 0 NA
57 hsa-miR-106a-5p ANKRD29 0.57 0.00015 -2.95 0 MirTarget -0.25 0 NA
58 hsa-miR-106b-5p ANKRD29 1.22 0 -2.95 0 MirTarget -0.7 0 NA
59 hsa-miR-93-5p ANKRD29 1.02 0 -2.95 0 miRNAWalker2 validate; MirTarget -0.66 0 NA
60 hsa-miR-106b-5p ANKRD50 1.22 0 0.25 0.02231 MirTarget; miRNATAP -0.2 0 NA
61 hsa-miR-93-5p ANKRD50 1.02 0 0.25 0.02231 MirTarget; miRNATAP -0.2 0 NA
62 hsa-miR-106b-5p ANO6 1.22 0 -1.5 0 MirTarget -0.42 0 NA
63 hsa-miR-93-5p ANO6 1.02 0 -1.5 0 MirTarget; miRNATAP -0.37 0 NA
64 hsa-miR-106b-5p ANXA11 1.22 0 -0.27 1.0E-5 mirMAP -0.11 0 NA
65 hsa-miR-106b-5p AP1G1 1.22 0 -0.11 0.12378 miRNAWalker2 validate -0.1 0 NA
66 hsa-miR-106b-5p AP2B1 1.22 0 0.26 0.00183 miRNAWalker2 validate -0.15 0 NA
67 hsa-miR-93-5p AP3S2 1.02 0 -0.11 0.06712 mirMAP -0.1 0 NA
68 hsa-miR-106a-5p APBB2 0.57 0.00015 -0.39 0.0002 MirTarget; miRNATAP -0.15 0 NA
69 hsa-miR-106b-5p APBB2 1.22 0 -0.39 0.0002 MirTarget; miRNATAP -0.42 0 NA
70 hsa-miR-93-5p APBB2 1.02 0 -0.39 0.0002 miRNAWalker2 validate; MirTarget; miRNATAP -0.4 0 NA
71 hsa-miR-106b-5p APC 1.22 0 -0.69 0 miRNAWalker2 validate; miRTarBase -0.31 0 23087084 miR 106b downregulates adenomatous polyposis coli and promotes cell proliferation in human hepatocellular carcinoma; Moreover we demonstrated that miR-106b downregulates APC expression by directly targeting the 3'-untranslated region of APC messenger RNA; Taken together our results suggest that miR-106b plays an important role in promoting the proliferation of human hepatoma cells and presents a novel mechanism of micro RNA-mediated direct suppression of APC expression in cancer cells
72 hsa-miR-20a-3p APC2 -0.22 0.17987 0.94 0 mirMAP -0.14 1.0E-5 NA
73 hsa-miR-106a-5p APCDD1 0.57 0.00015 -2.4 0 MirTarget -0.12 0.00041 NA
74 hsa-miR-106b-5p APCDD1 1.22 0 -2.4 0 MirTarget -0.33 0 NA
75 hsa-miR-93-5p APCDD1 1.02 0 -2.4 0 MirTarget -0.32 0 NA
76 hsa-miR-106b-5p APLP2 1.22 0 -0.34 1.0E-5 miRNAWalker2 validate -0.17 0 NA
77 hsa-miR-93-5p APLP2 1.02 0 -0.34 1.0E-5 miRNAWalker2 validate -0.12 0 NA
78 hsa-miR-106a-5p AR 0.57 0.00015 -1 0.00094 mirMAP -0.45 0 NA
79 hsa-miR-106b-5p AR 1.22 0 -1 0.00094 mirMAP -1.35 0 NA
80 hsa-miR-93-5p AR 1.02 0 -1 0.00094 mirMAP -1.31 0 NA
81 hsa-miR-93-5p ARAP2 1.02 0 -0.25 0.02981 MirTarget -0.13 0.00033 NA
82 hsa-miR-106b-5p ARHGAP1 1.22 0 0.21 1.0E-5 MirTarget; miRNATAP -0.11 0 NA
83 hsa-miR-106b-5p ARHGAP12 1.22 0 -0.58 0 miRNATAP -0.24 0 NA
84 hsa-miR-93-5p ARHGAP12 1.02 0 -0.58 0 miRNAWalker2 validate; miRNATAP -0.26 0 NA
85 hsa-miR-106b-5p ARHGAP19 1.22 0 -0.97 0 mirMAP -0.17 0 NA
86 hsa-miR-93-5p ARHGAP19 1.02 0 -0.97 0 mirMAP -0.12 0 NA
87 hsa-miR-106b-5p ARHGAP23 1.22 0 -0.93 0 mirMAP -0.22 0 NA
88 hsa-miR-93-5p ARHGAP23 1.02 0 -0.93 0 mirMAP -0.22 0 NA
89 hsa-miR-106a-5p ARHGAP24 0.57 0.00015 -1.41 0 MirTarget -0.11 0 NA
90 hsa-miR-106b-5p ARHGAP24 1.22 0 -1.41 0 MirTarget -0.32 0 NA
91 hsa-miR-93-5p ARHGAP24 1.02 0 -1.41 0 MirTarget -0.35 0 NA
92 hsa-miR-106b-5p ARHGAP26 1.22 0 -1.51 0 MirTarget; mirMAP; miRNATAP -0.29 0 NA
93 hsa-miR-93-5p ARHGAP26 1.02 0 -1.51 0 MirTarget; mirMAP; miRNATAP -0.32 0 NA
94 hsa-miR-93-5p ARHGAP32 1.02 0 0.43 9.0E-5 miRNAWalker2 validate -0.25 0 NA
95 hsa-miR-106b-5p ARHGEF3 1.22 0 -0.04 0.65559 MirTarget; miRNATAP -0.18 0 NA
96 hsa-miR-93-5p ARHGEF3 1.02 0 -0.04 0.65559 MirTarget; miRNATAP -0.21 0 NA
97 hsa-miR-106a-5p ARHGEF38 0.57 0.00015 0.07 0.77513 mirMAP -0.16 0.00387 NA
98 hsa-miR-106b-5p ARHGEF38 1.22 0 0.07 0.77513 mirMAP -0.75 0 NA
99 hsa-miR-106b-5p ARID4A 1.22 0 -0.86 0 MirTarget; miRNATAP -0.3 0 NA
100 hsa-miR-93-5p ARID4A 1.02 0 -0.86 0 MirTarget; miRNATAP -0.32 0 NA
101 hsa-miR-106b-5p ARL10 1.22 0 -1.27 0 mirMAP -0.33 0 NA
102 hsa-miR-93-5p ARL10 1.02 0 -1.27 0 mirMAP -0.3 0 NA
103 hsa-miR-106b-5p ARL13B 1.22 0 -0.46 0 miRNAWalker2 validate; MirTarget -0.16 0 NA
104 hsa-miR-93-5p ARL13B 1.02 0 -0.46 0 MirTarget -0.19 0 NA
105 hsa-miR-106b-5p ARL4A 1.22 0 -1.62 0 miRNATAP -0.21 0 NA
106 hsa-miR-93-5p ARL4A 1.02 0 -1.62 0 miRNATAP -0.26 0 NA
107 hsa-miR-93-5p ARNT2 1.02 0 1.54 0 mirMAP -0.18 0.00214 NA
108 hsa-miR-106b-5p ARSD 1.22 0 0.28 0.00266 mirMAP -0.23 0 NA
109 hsa-miR-93-5p ARSJ 1.02 0 -0.61 7.0E-5 miRNAWalker2 validate -0.29 0 NA
110 hsa-miR-93-5p ASB1 1.02 0 -0.93 0 miRNAWalker2 validate -0.13 0 NA
111 hsa-miR-106b-5p ASH1L 1.22 0 -0.4 1.0E-5 miRNATAP -0.26 0 NA
112 hsa-miR-93-5p ASH1L 1.02 0 -0.4 1.0E-5 miRNATAP -0.23 0 NA
113 hsa-miR-106a-5p ASPA 0.57 0.00015 -3.96 0 mirMAP -0.31 0 NA
114 hsa-miR-106b-5p ASPA 1.22 0 -3.96 0 mirMAP -0.9 0 NA
115 hsa-miR-20a-3p ASPA -0.22 0.17987 -3.96 0 mirMAP -0.24 0 NA
116 hsa-miR-93-5p ASPA 1.02 0 -3.96 0 mirMAP -0.87 0 NA
117 hsa-miR-106b-5p ATE1 1.22 0 -0.72 0 MirTarget -0.35 0 NA
118 hsa-miR-93-5p ATE1 1.02 0 -0.72 0 MirTarget -0.35 0 NA
119 hsa-miR-106b-5p ATF6 1.22 0 0.17 0.01386 mirMAP -0.13 0 NA
120 hsa-miR-106b-5p ATL3 1.22 0 -0.22 0.01349 MirTarget; miRNATAP -0.1 0.00027 NA
121 hsa-miR-106a-5p ATP1A2 0.57 0.00015 -5.48 0 MirTarget -0.6 0 NA
122 hsa-miR-106b-5p ATP1A2 1.22 0 -5.48 0 MirTarget; miRNATAP -1.47 0 NA
123 hsa-miR-93-5p ATP1A2 1.02 0 -5.48 0 MirTarget -1.33 0 NA
124 hsa-miR-20a-3p ATRNL1 -0.22 0.17987 -0.74 0.02081 MirTarget; mirMAP -0.21 0.00197 NA
125 hsa-miR-106b-5p ATRX 1.22 0 -0.59 0 mirMAP -0.26 0 NA
126 hsa-miR-106b-5p ATXN1 1.22 0 -0.11 0.17245 miRNATAP -0.25 0 NA
127 hsa-miR-93-5p ATXN1 1.02 0 -0.11 0.17245 miRNAWalker2 validate; miRNATAP -0.26 0 NA
128 hsa-miR-106b-5p ATXN1L 1.22 0 -0.97 0 miRNATAP -0.18 0 NA
129 hsa-miR-93-5p ATXN1L 1.02 0 -0.97 0 miRNATAP -0.19 0 NA
130 hsa-miR-106b-5p B3GALT2 1.22 0 -1.54 0 MirTarget -0.32 0 NA
131 hsa-miR-93-5p B3GALT2 1.02 0 -1.54 0 MirTarget -0.46 0 NA
132 hsa-miR-106b-5p BACH1 1.22 0 -0.49 0 mirMAP -0.15 0 NA
133 hsa-miR-93-5p BACH1 1.02 0 -0.49 0 mirMAP -0.18 0 NA
134 hsa-miR-93-5p BAZ2A 1.02 0 -0.1 0.10091 miRNAWalker2 validate -0.14 0 NA
135 hsa-miR-106b-5p BBX 1.22 0 -0.61 0 MirTarget; miRNATAP -0.2 0 NA
136 hsa-miR-93-5p BBX 1.02 0 -0.61 0 MirTarget; miRNATAP -0.21 0 NA
137 hsa-miR-106a-5p BCAS1 0.57 0.00015 1.43 1.0E-5 mirMAP -0.5 0 NA
138 hsa-miR-106b-5p BCAS1 1.22 0 1.43 1.0E-5 mirMAP -0.92 0 NA
139 hsa-miR-93-5p BCAS1 1.02 0 1.43 1.0E-5 mirMAP -0.87 0 NA
140 hsa-miR-20a-3p BCL2 -0.22 0.17987 -0.9 0 mirMAP -0.14 0.0001 NA
141 hsa-miR-106b-5p BCL2L2 1.22 0 -0.92 0 miRNATAP -0.21 0 NA
142 hsa-miR-93-5p BCL2L2 1.02 0 -0.92 0 miRNATAP -0.18 0 NA
143 hsa-miR-106b-5p BCL6 1.22 0 -1.26 0 miRNATAP -0.29 0 NA
144 hsa-miR-106b-5p BHLHE41 1.22 0 -1.53 0 miRNATAP -0.31 0 NA
145 hsa-miR-93-5p BHLHE41 1.02 0 -1.53 0 miRNATAP -0.35 0 NA
146 hsa-miR-106b-5p BMP2 1.22 0 -2.66 0 miRNATAP -0.27 1.0E-5 NA
147 hsa-miR-106b-5p BMPR2 1.22 0 -0.62 0 MirTarget; miRNATAP -0.28 0 NA
148 hsa-miR-93-5p BMPR2 1.02 0 -0.62 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.3 0 NA
149 hsa-miR-106a-5p BNC2 0.57 0.00015 -0.78 0 miRNATAP -0.17 0 NA
150 hsa-miR-106b-5p BNC2 1.22 0 -0.78 0 miRNATAP -0.57 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 POSITIVE REGULATION OF GENE EXPRESSION 148 1733 1.988e-14 9.248e-11
2 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 150 1805 1.197e-13 2.784e-10
3 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 148 1784 2.074e-13 3.217e-10
4 NEUROGENESIS 120 1402 7.589e-12 8.827e-09
5 RESPONSE TO ENDOGENOUS STIMULUS 122 1450 1.539e-11 1.194e-08
6 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 94 1004 1.521e-11 1.194e-08
7 CARDIOVASCULAR SYSTEM DEVELOPMENT 78 788 6.814e-11 3.963e-08
8 CIRCULATORY SYSTEM DEVELOPMENT 78 788 6.814e-11 3.963e-08
9 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 71 689 8.577e-11 4.435e-08
10 INTRACELLULAR SIGNAL TRANSDUCTION 126 1572 1.68e-10 7.815e-08
11 CELL DEVELOPMENT 117 1426 2.036e-10 8.614e-08
12 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 130 1656 3.211e-10 1.245e-07
13 POSITIVE REGULATION OF MOLECULAR FUNCTION 136 1791 1.063e-09 3.694e-07
14 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 89 1008 1.111e-09 3.694e-07
15 HEART DEVELOPMENT 52 466 2.077e-09 6.038e-07
16 REGULATION OF PHOSPHORUS METABOLIC PROCESS 125 1618 1.998e-09 6.038e-07
17 TISSUE DEVELOPMENT 119 1518 2.206e-09 6.038e-07
18 REGULATION OF PROTEIN MODIFICATION PROCESS 130 1710 2.469e-09 6.382e-07
19 REGULATION OF CELL DIFFERENTIATION 116 1492 5.802e-09 1.421e-06
20 REGULATION OF GTPASE ACTIVITY 65 673 7.514e-09 1.748e-06
21 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 36 278 1.47e-08 3.256e-06
22 NEURON DIFFERENTIATION 77 874 1.745e-08 3.691e-06
23 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 134 1848 2.543e-08 5.144e-06
24 REGULATION OF HYDROLASE ACTIVITY 102 1327 9.43e-08 1.828e-05
25 EPITHELIUM DEVELOPMENT 79 945 1.058e-07 1.969e-05
26 BONE DEVELOPMENT 24 156 1.523e-07 2.726e-05
27 POSITIVE REGULATION OF CATALYTIC ACTIVITY 112 1518 1.754e-07 3.022e-05
28 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 64 724 2.614e-07 4.343e-05
29 REGULATION OF KINASE ACTIVITY 67 776 3.23e-07 5.182e-05
30 SINGLE ORGANISM BEHAVIOR 41 384 3.511e-07 5.446e-05
31 BEHAVIOR 50 516 3.803e-07 5.709e-05
32 NEURON DEVELOPMENT 61 687 4.317e-07 6.277e-05
33 RESPONSE TO GROWTH FACTOR 47 475 4.682e-07 6.601e-05
34 MUSCLE STRUCTURE DEVELOPMENT 44 432 4.934e-07 6.617e-05
35 CELLULAR RESPONSE TO OXYGEN LEVELS 22 143 4.977e-07 6.617e-05
36 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 64 740 5.634e-07 7.282e-05
37 CENTRAL NERVOUS SYSTEM DEVELOPMENT 72 872 6.348e-07 7.984e-05
38 RESPONSE TO OXYGEN LEVELS 35 311 7.398e-07 9.059e-05
39 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 118 1672 7.939e-07 9.472e-05
40 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 25 184 9.455e-07 0.00011
41 RESPONSE TO OXYGEN CONTAINING COMPOUND 101 1381 1.124e-06 0.0001276
42 ORGAN MORPHOGENESIS 69 841 1.374e-06 0.0001523
43 POSITIVE REGULATION OF CELL COMMUNICATION 109 1532 1.508e-06 0.000161
44 RESPONSE TO HORMONE 72 893 1.523e-06 0.000161
45 PROTEIN PHOSPHORYLATION 75 944 1.586e-06 0.000164
46 POSITIVE REGULATION OF CATABOLIC PROCESS 40 395 1.877e-06 0.0001878
47 VASCULATURE DEVELOPMENT 45 469 1.896e-06 0.0001878
48 SKELETAL SYSTEM DEVELOPMENT 44 455 2.004e-06 0.0001943
49 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 80 1036 2.122e-06 0.0001975
50 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 80 1036 2.122e-06 0.0001975
51 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 86 1142 2.382e-06 0.0002174
52 POSITIVE REGULATION OF HYDROLASE ACTIVITY 72 905 2.461e-06 0.0002202
53 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 49 541 3.445e-06 0.0002968
54 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 49 541 3.445e-06 0.0002968
55 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 62 750 3.75e-06 0.0003061
56 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 42 437 3.986e-06 0.0003061
57 REGULATION OF CELL PROJECTION ORGANIZATION 50 558 3.71e-06 0.0003061
58 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 47 513 4.002e-06 0.0003061
59 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 105 1492 3.909e-06 0.0003061
60 NEGATIVE REGULATION OF PHOSPHORYLATION 41 422 3.969e-06 0.0003061
61 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 46 498 4.078e-06 0.0003061
62 NEGATIVE REGULATION OF CELL COMMUNICATION 88 1192 4.015e-06 0.0003061
63 REGULATION OF CELL DEVELOPMENT 67 836 4.35e-06 0.0003213
64 POSITIVE REGULATION OF CELL DIFFERENTIATION 66 823 5.029e-06 0.0003656
65 POSITIVE REGULATION OF CELL DEVELOPMENT 44 472 5.211e-06 0.000373
66 RESPONSE TO NITROGEN COMPOUND 68 859 5.582e-06 0.0003935
67 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 24 190 5.669e-06 0.0003937
68 CELLULAR RESPONSE TO HORMONE STIMULUS 49 552 5.997e-06 0.0004103
69 UROGENITAL SYSTEM DEVELOPMENT 32 299 6.359e-06 0.0004288
70 REGULATION OF SYSTEM PROCESS 46 507 6.539e-06 0.0004347
71 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 64 799 7.279e-06 0.0004704
72 PROTEIN LOCALIZATION 121 1805 7.192e-06 0.0004704
73 DEVELOPMENTAL MATURATION 24 193 7.438e-06 0.0004741
74 REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 17 109 8.028e-06 0.0005048
75 REGULATION OF CELLULAR COMPONENT MOVEMENT 62 771 8.968e-06 0.0005564
76 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 98 1395 9.092e-06 0.0005567
77 POSITIVE REGULATION OF RESPONSE TO STIMULUS 127 1929 9.98e-06 0.0006031
78 POSITIVE REGULATION OF NEURON DIFFERENTIATION 32 306 1.026e-05 0.0006121
79 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 91 1275 1.054e-05 0.0006206
80 MUSCLE CELL DIFFERENTIATION 27 237 1.068e-05 0.0006212
81 VESICLE ORGANIZATION 30 280 1.201e-05 0.0006897
82 REGULATION OF CELL MORPHOGENESIS 48 552 1.286e-05 0.0007298
83 REGULATION OF NEURON DIFFERENTIATION 48 554 1.414e-05 0.0007854
84 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 76 1021 1.418e-05 0.0007854
85 REGULATION OF ACTIN FILAMENT BASED PROCESS 32 312 1.524e-05 0.0008341
86 RHYTHMIC PROCESS 31 298 1.559e-05 0.0008434
87 FOREBRAIN DEVELOPMENT 35 357 1.642e-05 0.000878
88 ACTIVATION OF MAPKK ACTIVITY 11 52 1.719e-05 0.000909
89 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER INVOLVED IN CELLULAR RESPONSE TO CHEMICAL STIMULUS 8 27 1.783e-05 0.000932
90 NEGATIVE REGULATION OF GENE EXPRESSION 102 1493 1.89e-05 0.0009773
91 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 82 1135 1.913e-05 0.0009781
92 NEURON PROJECTION DEVELOPMENT 47 545 1.953e-05 0.0009879
93 REGULATION OF TRANSFERASE ACTIVITY 71 946 2.093e-05 0.001047
94 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 31 303 2.163e-05 0.001071
95 REGULATION OF DEVELOPMENTAL GROWTH 30 289 2.215e-05 0.001074
96 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 103 1517 2.212e-05 0.001074
97 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 42 470 2.346e-05 0.001126
98 REGULATION OF CATABOLIC PROCESS 58 731 2.573e-05 0.001222
99 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 51 616 2.621e-05 0.001232
100 TUBE DEVELOPMENT 47 552 2.696e-05 0.001255
101 COGNITION 27 251 3.008e-05 0.001386
102 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 71 957 3.043e-05 0.001388
103 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 82 1152 3.237e-05 0.001462
104 MEMORY 15 98 3.396e-05 0.001505
105 NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 15 98 3.396e-05 0.001505
106 EPITHELIAL CELL DIFFERENTIATION 43 495 3.688e-05 0.001619
107 HOMEOSTATIC PROCESS 92 1337 3.821e-05 0.001662
108 STRIATED MUSCLE CELL DIFFERENTIATION 21 173 3.905e-05 0.001667
109 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 9 38 3.874e-05 0.001667
110 REGULATION OF MAPK CASCADE 53 660 4.163e-05 0.001745
111 REGULATION OF ORGANELLE ORGANIZATION 83 1178 4.139e-05 0.001745
112 POSITIVE REGULATION OF KINASE ACTIVITY 42 482 4.219e-05 0.001753
113 TELENCEPHALON DEVELOPMENT 25 228 4.265e-05 0.001756
114 REGULATION OF TRANSPORT 117 1804 4.489e-05 0.001832
115 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 25 229 4.587e-05 0.001856
116 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 39 437 4.679e-05 0.001877
117 ORGAN GROWTH 12 68 4.911e-05 0.001953
118 KIDNEY EPITHELIUM DEVELOPMENT 17 125 4.985e-05 0.001966
119 SODIUM ION TRANSMEMBRANE TRANSPORT 14 90 5.126e-05 0.001971
120 POSITIVE REGULATION OF MAPK CASCADE 41 470 5.06e-05 0.001971
121 MESONEPHROS DEVELOPMENT 14 90 5.126e-05 0.001971
122 BONE MORPHOGENESIS 13 79 5.169e-05 0.001971
123 CELLULAR RESPONSE TO PEPTIDE 28 274 5.437e-05 0.002057
124 MUSCLE TISSUE DEVELOPMENT 28 275 5.798e-05 0.002128
125 ENSHEATHMENT OF NEURONS 14 91 5.809e-05 0.002128
126 AXON ENSHEATHMENT 14 91 5.809e-05 0.002128
127 BLOOD VESSEL MORPHOGENESIS 34 364 5.772e-05 0.002128
128 CELLULAR RESPONSE TO NITROGEN COMPOUND 43 505 5.868e-05 0.002133
129 CHEMICAL HOMEOSTASIS 65 874 6.149e-05 0.002218
130 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 77 1087 6.642e-05 0.002377
131 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 33 352 6.873e-05 0.002441
132 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 92 1360 7.146e-05 0.002507
133 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 34 368 7.167e-05 0.002507
134 REGULATION OF CELL DEATH 98 1472 7.52e-05 0.002611
135 HEAD DEVELOPMENT 55 709 7.596e-05 0.002618
136 NEURON PROJECTION MORPHOGENESIS 36 402 8.439e-05 0.002832
137 RESPONSE TO ABIOTIC STIMULUS 73 1024 8.452e-05 0.002832
138 REGULATION OF CYTOPLASMIC TRANSPORT 41 481 8.459e-05 0.002832
139 ACTION POTENTIAL 14 94 8.357e-05 0.002832
140 ACTIN FILAMENT BASED PROCESS 39 450 8.804e-05 0.002926
141 SODIUM ION TRANSPORT 18 144 9.321e-05 0.003076
142 POSITIVE REGULATION OF LOCOMOTION 37 420 9.49e-05 0.00311
143 CARDIAC SEPTUM DEVELOPMENT 13 85 0.0001126 0.003614
144 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 18 146 0.0001115 0.003614
145 HEART PROCESS 13 85 0.0001126 0.003614
146 REPRODUCTIVE SYSTEM DEVELOPMENT 36 408 0.0001137 0.003624
147 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 64 876 0.0001166 0.003692
148 ADULT BEHAVIOR 17 135 0.0001319 0.004148
149 MULTICELLULAR ORGANISMAL SIGNALING 16 123 0.0001404 0.004386
150 CELLULAR COMPONENT MORPHOGENESIS 65 900 0.0001434 0.004449
151 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 24 232 0.0001499 0.004619
152 SECRETORY GRANULE ORGANIZATION 7 27 0.0001542 0.004671
153 CELL PROJECTION ORGANIZATION 65 902 0.0001527 0.004671
154 INOSITOL LIPID MEDIATED SIGNALING 16 124 0.0001546 0.004671
155 ENDOCHONDRAL BONE MORPHOGENESIS 9 45 0.0001584 0.004755
156 PROTEIN UBIQUITINATION 49 629 0.0001675 0.004944
157 REGULATION OF CELL ADHESION 49 629 0.0001675 0.004944
158 PHOSPHORYLATION 83 1228 0.0001679 0.004944
159 RESPONSE TO STEROID HORMONE 41 497 0.0001714 0.005017
160 NEGATIVE REGULATION OF CELL CYCLE 37 433 0.0001757 0.005109
161 REGULATION OF GROWTH 49 633 0.0001945 0.005586
162 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 48 616 0.0001934 0.005586
163 RESPONSE TO PEPTIDE 35 404 0.0002004 0.005722
164 CONNECTIVE TISSUE DEVELOPMENT 21 194 0.0002037 0.00578
165 CARDIAC MUSCLE CELL ACTION POTENTIAL 8 37 0.0002072 0.005844
166 REGULATION OF CELLULAR PROTEIN LOCALIZATION 44 552 0.0002161 0.006058
167 MUSCLE CELL DEVELOPMENT 16 128 0.0002243 0.006251
168 REGULATION OF CIRCADIAN RHYTHM 14 103 0.0002263 0.006269
169 REGULATION OF BINDING 27 283 0.0002298 0.006327
170 RESPONSE TO MECHANICAL STIMULUS 22 210 0.0002326 0.006365
171 LOCOMOTION 76 1114 0.0002395 0.006517
172 REGULATION OF NEURON PROJECTION DEVELOPMENT 35 408 0.0002417 0.006539
173 ADULT LOCOMOTORY BEHAVIOR 12 80 0.0002469 0.006581
174 APPENDAGE DEVELOPMENT 19 169 0.0002476 0.006581
175 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 122 1977 0.0002503 0.006581
176 CARDIAC MUSCLE CELL CONTRACTION 7 29 0.0002503 0.006581
177 LIMB DEVELOPMENT 19 169 0.0002476 0.006581
178 PERIPHERAL NERVOUS SYSTEM DEVELOPMENT 11 69 0.0002571 0.006721
179 POSITIVE REGULATION OF CELL PROLIFERATION 59 814 0.0002633 0.006845
180 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORT 9 48 0.0002654 0.006861
181 MEMBRANE DEPOLARIZATION DURING CARDIAC MUSCLE CELL ACTION POTENTIAL 5 14 0.0002696 0.00693
182 NEGATIVE REGULATION OF CELL DIFFERENTIATION 47 609 0.0002794 0.007142
183 SENSORY ORGAN DEVELOPMENT 40 493 0.000288 0.007324
184 VASCULOGENESIS 10 59 0.0002914 0.007369
185 VESICLE CYTOSKELETAL TRAFFICKING 8 39 0.0003047 0.007665
186 EPITHELIAL CELL DEVELOPMENT 20 186 0.0003123 0.007728
187 REGULATION OF VESICLE MEDIATED TRANSPORT 38 462 0.00031 0.007728
188 POSITIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 7 30 0.0003138 0.007728
189 RESPONSE TO BMP 13 94 0.0003156 0.007728
190 CELLULAR RESPONSE TO BMP STIMULUS 13 94 0.0003156 0.007728
191 SKELETAL SYSTEM MORPHOGENESIS 21 201 0.0003315 0.008075
192 REGULATION OF CELL SUBSTRATE ADHESION 19 173 0.0003342 0.008099
193 CELLULAR RESPONSE TO INSULIN STIMULUS 17 146 0.0003409 0.008219
194 REGULATION OF CELLULAR LOCALIZATION 84 1277 0.0003665 0.00879
195 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 17 147 0.0003696 0.008819
196 CELLULAR RESPONSE TO GLUCOSE STARVATION 7 31 0.0003896 0.009249
NumGOOverlapSizeP ValueAdj. P Value
1 ENZYME BINDING 143 1737 1.034e-12 9.609e-10
2 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 102 1199 4.808e-10 2.233e-07
3 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 42 328 1.307e-09 4.047e-07
4 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 62 629 7.844e-09 1.822e-06
5 MOLECULAR FUNCTION REGULATOR 105 1353 3.676e-08 6.831e-06
6 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 36 315 3.541e-07 5.142e-05
7 ENZYME REGULATOR ACTIVITY 78 959 3.874e-07 5.142e-05
8 GTPASE BINDING 34 295 6.127e-07 7.115e-05
9 SEQUENCE SPECIFIC DNA BINDING 81 1037 1.168e-06 0.0001206
10 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 28 226 1.429e-06 0.0001207
11 TRANSCRIPTION FACTOR BINDING 49 524 1.4e-06 0.0001207
12 MACROMOLECULAR COMPLEX BINDING 101 1399 2.007e-06 0.0001554
13 NUCLEOSIDE TRIPHOSPHATASE REGULATOR ACTIVITY 35 329 2.719e-06 0.0001943
14 SMAD BINDING 14 72 3.614e-06 0.0002298
15 BINDING BRIDGING 23 173 3.71e-06 0.0002298
16 DOUBLE STRANDED DNA BINDING 62 764 6.745e-06 0.0003916
17 REGULATORY REGION NUCLEIC ACID BINDING 65 818 7.986e-06 0.0004122
18 RAB GTPASE BINDING 18 120 7.688e-06 0.0004122
19 PROTEIN HOMODIMERIZATION ACTIVITY 59 722 9.159e-06 0.0004254
20 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 19 133 8.965e-06 0.0004254
21 CALCIUM ION BINDING 57 697 1.271e-05 0.0005621
22 RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 16 104 1.757e-05 0.0007421
23 ENZYME ACTIVATOR ACTIVITY 42 471 2.467e-05 0.0009963
24 PROTEIN DIMERIZATION ACTIVITY 82 1149 2.954e-05 0.001144
25 MAP KINASE KINASE KINASE ACTIVITY 7 22 3.611e-05 0.001342
26 CYTOSKELETAL PROTEIN BINDING 62 819 5.476e-05 0.001956
27 CORE PROMOTER PROXIMAL REGION DNA BINDING 34 371 8.407e-05 0.002893
28 UBIQUITIN LIKE PROTEIN TRANSFERASE ACTIVITY 37 420 9.49e-05 0.003149
29 ACTIN BINDING 35 393 0.0001174 0.003592
30 KINASE ACTIVITY 62 842 0.0001199 0.003592
31 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II ACTIVATING TRANSCRIPTION FACTOR BINDING 10 53 0.0001156 0.003592
32 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 47 588 0.0001249 0.003626
33 PROTEIN KINASE ACTIVITY 50 640 0.0001345 0.003786
34 X1 PHOSPHATIDYLINOSITOL BINDING 6 19 0.0001396 0.003814
35 RNA POLYMERASE II ACTIVATING TRANSCRIPTION FACTOR BINDING 8 36 0.0001691 0.004488
36 VOLTAGE GATED SODIUM CHANNEL ACTIVITY 6 20 0.0001918 0.004949
37 ACTIVATING TRANSCRIPTION FACTOR BINDING 10 57 0.0002174 0.005458
38 RECEPTOR SIGNALING PROTEIN SERINE THREONINE KINASE ACTIVITY 13 92 0.0002542 0.006215
39 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 23 228 0.0002946 0.007018
40 RECEPTOR SIGNALING PROTEIN ACTIVITY 19 172 0.0003104 0.007209
NumGOOverlapSizeP ValueAdj. P Value
1 NEURON PART 100 1265 3.252e-08 1.899e-05
2 NEURON PROJECTION 79 942 9.269e-08 2.706e-05
3 CELL PROJECTION 123 1786 1.58e-06 0.0003076
4 MEMBRANE REGION 85 1134 3.287e-06 0.0003839
5 EARLY ENDOSOME 33 301 2.715e-06 0.0003839
6 ENDOSOME 64 793 5.715e-06 0.0005563
7 PLASMA MEMBRANE RAFT 15 86 6.72e-06 0.0005606
8 ACTIN CYTOSKELETON 41 444 1.36e-05 0.0008845
9 GOLGI APPARATUS 100 1445 1.363e-05 0.0008845
10 AXON 39 418 1.735e-05 0.001013
11 PML BODY 15 97 3e-05 0.001365
12 CELL JUNCTION 82 1151 3.14e-05 0.001365
13 SYNAPSE 59 754 3.273e-05 0.001365
14 CUL3 RING UBIQUITIN LIGASE COMPLEX 12 64 2.616e-05 0.001365
15 CELL PROJECTION PART 70 946 3.763e-05 0.001465
16 VACUOLE 83 1180 4.39e-05 0.001602
17 MEMBRANE MICRODOMAIN 29 288 5.269e-05 0.00181
18 CELL LEADING EDGE 33 350 6.152e-05 0.001996
19 PLASMA MEMBRANE REGION 68 929 6.764e-05 0.002079
20 INTRACELLULAR VESICLE 85 1259 0.0001452 0.00424
21 PROTEIN KINASE COMPLEX 13 90 0.0002034 0.005399
22 SOMATODENDRITIC COMPARTMENT 50 650 0.0001951 0.005399
23 PERINUCLEAR REGION OF CYTOPLASM 49 642 0.0002701 0.006573
24 VOLTAGE GATED SODIUM CHANNEL COMPLEX 5 14 0.0002696 0.006573

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04710_Circadian_rhythm_._mammal 7 23 4.988e-05 0.004318
2 hsa04144_Endocytosis 23 203 5.127e-05 0.004318
3 hsa04390_Hippo_signaling_pathway 19 154 7.197e-05 0.004318
4 hsa04151_PI3K_AKT_signaling_pathway 31 351 0.0003257 0.01466
5 hsa04630_Jak.STAT_signaling_pathway 17 155 0.0006837 0.02461
6 hsa04010_MAPK_signaling_pathway 24 268 0.001217 0.03651
7 hsa04350_TGF.beta_signaling_pathway 11 85 0.001559 0.04009
8 hsa04722_Neurotrophin_signaling_pathway 14 127 0.001873 0.04215
9 hsa04910_Insulin_signaling_pathway 14 138 0.004038 0.08077
10 hsa04912_GnRH_signaling_pathway 11 101 0.006049 0.1089
11 hsa04540_Gap_junction 10 90 0.00754 0.1234
12 hsa04150_mTOR_signaling_pathway 7 52 0.008698 0.1305
13 hsa04510_Focal_adhesion 17 200 0.009766 0.1352
14 hsa04920_Adipocytokine_signaling_pathway 8 68 0.01157 0.1487
15 hsa04115_p53_signaling_pathway 8 69 0.01258 0.151
16 hsa04962_Vasopressin.regulated_water_reabsorption 6 44 0.01387 0.156
17 hsa04914_Progesterone.mediated_oocyte_maturation 9 87 0.01698 0.1798
18 hsa04210_Apoptosis 9 89 0.01945 0.1899
19 hsa04310_Wnt_signaling_pathway 13 151 0.02004 0.1899
20 hsa00770_Pantothenate_and_CoA_biosynthesis 3 16 0.03347 0.2772
21 hsa04114_Oocyte_meiosis 10 114 0.03437 0.2772
22 hsa04270_Vascular_smooth_muscle_contraction 10 116 0.03806 0.2772
23 hsa04720_Long.term_potentiation 7 70 0.03894 0.2772
24 hsa04972_Pancreatic_secretion 9 101 0.03983 0.2772
25 hsa04960_Aldosterone.regulated_sodium_reabsorption 5 42 0.04034 0.2772
26 hsa00340_Histidine_metabolism 4 29 0.04052 0.2772
27 hsa04976_Bile_secretion 7 71 0.04159 0.2772
28 hsa04970_Salivary_secretion 8 89 0.04875 0.3116
29 hsa04971_Gastric_acid_secretion 7 74 0.05019 0.3116
30 hsa04380_Osteoclast_differentiation 10 128 0.06592 0.3883
31 hsa04146_Peroxisome 7 79 0.06688 0.3883
32 hsa04360_Axon_guidance 10 130 0.07158 0.3909
33 hsa04014_Ras_signaling_pathway 16 236 0.07167 0.3909
34 hsa00565_Ether_lipid_metabolism 4 36 0.07864 0.4146
35 hsa04530_Tight_junction 10 133 0.08061 0.4146
36 hsa04916_Melanogenesis 8 101 0.08798 0.4399
37 hsa04012_ErbB_signaling_pathway 7 87 0.09975 0.4769
38 hsa04120_Ubiquitin_mediated_proteolysis 10 139 0.1007 0.4769
39 hsa04020_Calcium_signaling_pathway 12 177 0.1079 0.4914
40 hsa04340_Hedgehog_signaling_pathway 5 56 0.1092 0.4914
41 hsa00071_Fatty_acid_metabolism 4 43 0.1294 0.5681
42 hsa00310_Lysine_degradation 4 44 0.1376 0.5896
43 hsa04141_Protein_processing_in_endoplasmic_reticulum 11 168 0.1423 0.5956
44 hsa00604_Glycosphingolipid_biosynthesis_._ganglio_series 2 15 0.1462 0.5983
45 hsa04514_Cell_adhesion_molecules_.CAMs. 9 136 0.1652 0.6606
46 hsa00561_Glycerolipid_metabolism 4 50 0.1904 0.745
47 hsa00670_One_carbon_pool_by_folate 2 18 0.1954 0.7484
48 hsa03320_PPAR_signaling_pathway 5 70 0.2111 0.7756
49 hsa04730_Long.term_depression 5 70 0.2111 0.7756
50 hsa04660_T_cell_receptor_signaling_pathway 7 108 0.2189 0.7879
51 hsa00592_alpha.Linolenic_acid_metabolism 2 20 0.2292 0.8089
52 hsa04520_Adherens_junction 5 73 0.2361 0.8172
53 hsa04662_B_cell_receptor_signaling_pathway 5 75 0.2532 0.8463
54 hsa04370_VEGF_signaling_pathway 5 76 0.2618 0.8463
55 hsa00410_beta.Alanine_metabolism 2 22 0.2633 0.8463
56 hsa00532_Glycosaminoglycan_biosynthesis_._chondroitin_sulfate 2 22 0.2633 0.8463
57 hsa00600_Sphingolipid_metabolism 3 40 0.2718 0.8585
58 hsa04964_Proximal_tubule_bicarbonate_reclamation 2 23 0.2804 0.8674
59 hsa00350_Tyrosine_metabolism 3 41 0.2843 0.8674
60 hsa00564_Glycerophospholipid_metabolism 5 80 0.297 0.8777
61 hsa00760_Nicotinate_and_nicotinamide_metabolism 2 24 0.2974 0.8777
62 hsa04973_Carbohydrate_digestion_and_absorption 3 44 0.322 0.9256
63 hsa03015_mRNA_surveillance_pathway 5 83 0.3239 0.9256
64 hsa04110_Cell_cycle 7 128 0.3615 1
65 hsa04810_Regulation_of_actin_cytoskeleton 11 214 0.379 1
66 hsa00512_Mucin_type_O.Glycan_biosynthesis 2 30 0.3974 1
67 hsa04666_Fc_gamma_R.mediated_phagocytosis 5 95 0.4326 1
68 hsa00230_Purine_metabolism 8 162 0.4542 1
69 hsa04142_Lysosome 6 121 0.4711 1
70 hsa04070_Phosphatidylinositol_signaling_system 4 78 0.4743 1
71 hsa04062_Chemokine_signaling_pathway 9 189 0.4888 1
72 hsa00270_Cysteine_and_methionine_metabolism 2 36 0.4904 1
73 hsa04620_Toll.like_receptor_signaling_pathway 5 102 0.4946 1
74 hsa00280_Valine._leucine_and_isoleucine_degradation 2 44 0.5993 1
75 hsa02010_ABC_transporters 2 44 0.5993 1
76 hsa04610_Complement_and_coagulation_cascades 3 69 0.6111 1
77 hsa04975_Fat_digestion_and_absorption 2 46 0.6236 1
78 hsa03018_RNA_degradation 3 71 0.6305 1
79 hsa04330_Notch_signaling_pathway 2 47 0.6354 1
80 hsa00520_Amino_sugar_and_nucleotide_sugar_metabolism 2 48 0.6468 1
81 hsa04260_Cardiac_muscle_contraction 3 77 0.6846 1
82 hsa00983_Drug_metabolism_._other_enzymes 2 52 0.6898 1
83 hsa04664_Fc_epsilon_RI_signaling_pathway 3 79 0.7013 1
84 hsa00500_Starch_and_sucrose_metabolism 2 54 0.7096 1
85 hsa04974_Protein_digestion_and_absorption 3 81 0.7172 1
86 hsa00562_Inositol_phosphate_metabolism 2 57 0.7373 1
87 hsa04512_ECM.receptor_interaction 3 85 0.7472 1
88 hsa00590_Arachidonic_acid_metabolism 2 59 0.7545 1
89 hsa04640_Hematopoietic_cell_lineage 3 88 0.768 1
90 hsa04670_Leukocyte_transendothelial_migration 4 117 0.7827 1
91 hsa00010_Glycolysis_._Gluconeogenesis 2 65 0.8003 1
92 hsa00240_Pyrimidine_metabolism 3 99 0.8324 1
93 hsa00980_Metabolism_of_xenobiotics_by_cytochrome_P450 2 71 0.8384 1
94 hsa04145_Phagosome 5 156 0.841 1
95 hsa00982_Drug_metabolism_._cytochrome_P450 2 73 0.8496 1
96 hsa04612_Antigen_processing_and_presentation 2 78 0.8745 1
97 hsa03008_Ribosome_biogenesis_in_eukaryotes 2 81 0.8875 1
98 hsa04650_Natural_killer_cell_mediated_cytotoxicity 3 136 0.9494 1
99 hsa03013_RNA_transport 2 152 0.993 1
100 hsa04740_Olfactory_transduction 2 388 1 1

Quest ID: 381775f8fd6895d9aa43ca09bffedfea