Visible node/edge number:
Node colors:
Node labels:

show label of nodes with degree >=

Node sizes:
Edge colors:
Edge widths factor:
Layout:

gravity >=

edgeLength =

GRN in network:

Notice: IE browser need to manually refresh (F5) this page after resetting the network.

This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-106b-5p APC 0.65 0 -0.18 0.06792 miRNAWalker2 validate; miRTarBase -0.15 0.00024 23087084 miR 106b downregulates adenomatous polyposis coli and promotes cell proliferation in human hepatocellular carcinoma; Moreover we demonstrated that miR-106b downregulates APC expression by directly targeting the 3'-untranslated region of APC messenger RNA; Taken together our results suggest that miR-106b plays an important role in promoting the proliferation of human hepatoma cells and presents a novel mechanism of micro RNA-mediated direct suppression of APC expression in cancer cells
2 hsa-miR-21-5p APC 1.51 0 -0.18 0.06792 miRNAWalker2 validate -0.17 0 23773491; 24832083 The prognostic significance of APC gene mutation and miR 21 expression in advanced stage colorectal cancer; The aim of this study was to analyse the association of APC gene mutation and miR-21 expression with clinical outcome in CRC patients; APC gene mutation and expression of APC and miR-21 were analysed by direct DNA sequencing and real-time reverse transcription polymerase chain reaction; APC gene expression was low in CRC and negatively correlated with miR-21 expression and gene mutation; In Taiwan downregulation of the APC gene in CRC correlated with gene mutation and miR-21 upregulation; APC mutation and miR-21 expression could be used to predict the clinical outcome of CRC especially in patients with advanced disease;MicroRNA 21 promotes tumour malignancy via increased nuclear translocation of β catenin and predicts poor outcome in APC mutated but not in APC wild type colorectal cancer; However in our preliminary data the prognostic value of miR-21 levels was observed only in adenomatous polyposis coli APC-mutated tumours not in APC-wild-type tumours; We enrolled 165 colorectal tumour to determine APC mutation miR-21 levels and nuclear β-catenin expression by direct sequencing real-time PCR and immunohistochemistry
3 hsa-let-7a-5p APC2 -0.33 0.00046 1.72 0 TargetScan -0.3 0.00538 NA
4 hsa-miR-125a-5p APC2 -0.91 0 1.72 0 mirMAP -0.2 0.0003 NA
5 hsa-miR-194-3p APC2 -0.77 3.0E-5 1.72 0 mirMAP -0.17 0.00111 NA
6 hsa-miR-199a-5p APC2 -1.99 0 1.72 0 mirMAP -0.1 0.00178 NA
7 hsa-miR-20a-3p APC2 -0.32 0.04679 1.72 0 mirMAP -0.25 7.0E-5 NA
8 hsa-miR-23b-5p APC2 -1.05 0 1.72 0 mirMAP -0.22 0.0013 NA
9 hsa-miR-28-5p APC2 -0.43 0 1.72 0 mirMAP -0.3 0.00527 NA
10 hsa-miR-505-5p APC2 -0.77 1.0E-5 1.72 0 mirMAP -0.15 0.00924 NA
11 hsa-miR-320a AXIN1 0.33 0.02214 0.3 0.00968 miRNAWalker2 validate -0.1 0.00946 NA
12 hsa-miR-15b-5p AXIN2 0.23 0.08248 0.11 0.75298 miRTarBase; MirTarget; miRNATAP -0.45 0.00081 NA
13 hsa-miR-16-2-3p AXIN2 -0.03 0.80516 0.11 0.75298 mirMAP -0.64 0 NA
14 hsa-miR-16-5p AXIN2 -0.4 0.0001 0.11 0.75298 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.49 0.00421 NA
15 hsa-miR-195-3p AXIN2 -1.09 0 0.11 0.75298 mirMAP -0.31 0.00083 NA
16 hsa-miR-195-5p AXIN2 -1.86 0 0.11 0.75298 MirTarget; miRNATAP -0.25 0.00506 NA
17 hsa-miR-26b-3p AXIN2 -1.26 0 0.11 0.75298 MirTarget -0.59 3.0E-5 NA
18 hsa-miR-326 AXIN2 -1.88 0 0.11 0.75298 miRanda -0.36 2.0E-5 NA
19 hsa-miR-338-5p AXIN2 -0.22 0.25239 0.11 0.75298 miRNATAP -0.34 0.00017 NA
20 hsa-miR-497-5p AXIN2 -1.41 0 0.11 0.75298 MirTarget; miRNATAP -0.29 0.00329 NA
21 hsa-miR-616-3p AXIN2 -0.7 2.0E-5 0.11 0.75298 MirTarget -0.42 8.0E-5 NA
22 hsa-miR-15b-5p BTRC 0.23 0.08248 -0 0.97671 MirTarget; miRNATAP -0.12 0 NA
23 hsa-miR-16-5p BTRC -0.4 0.0001 -0 0.97671 miRNAWalker2 validate; MirTarget; miRNATAP -0.17 0 NA
24 hsa-miR-193a-3p BTRC -0.12 0.30939 -0 0.97671 MirTarget; miRanda -0.15 0 NA
25 hsa-miR-193b-3p BTRC -0.17 0.27202 -0 0.97671 miRNAWalker2 validate -0.16 0 NA
26 hsa-miR-361-3p BTRC 0.28 0.00549 -0 0.97671 MirTarget; PITA; miRNATAP -0.1 0.00495 NA
27 hsa-miR-497-5p BTRC -1.41 0 -0 0.97671 MirTarget; miRNATAP -0.11 0 NA
28 hsa-miR-505-3p BTRC -1.2 0 -0 0.97671 MirTarget -0.13 0 NA
29 hsa-miR-142-3p CACYBP -1.42 0 0.95 0 miRanda -0.14 0 NA
30 hsa-miR-195-3p CACYBP -1.09 0 0.95 0 mirMAP -0.15 0 NA
31 hsa-miR-26b-3p CACYBP -1.26 0 0.95 0 MirTarget -0.26 0 NA
32 hsa-miR-30a-3p CACYBP -1.53 0 0.95 0 MirTarget -0.22 0 NA
33 hsa-miR-30e-3p CACYBP -1.21 0 0.95 0 MirTarget -0.35 0 NA
34 hsa-miR-576-5p CACYBP -0.38 0.00471 0.95 0 mirMAP -0.11 0.00429 NA
35 hsa-miR-146b-3p CAMK2A -1.21 0 -0.33 0.35691 miRNATAP -0.26 0.00225 NA
36 hsa-miR-15b-3p CAMK2A 0.24 0.09977 -0.33 0.35691 mirMAP -0.44 0.00022 NA
37 hsa-miR-21-3p CAMK2A -0.48 0.003 -0.33 0.35691 MirTarget -0.43 5.0E-5 NA
38 hsa-miR-582-3p CAMK2A -0.65 0.00249 -0.33 0.35691 mirMAP -0.24 0.00279 NA
39 hsa-miR-7-1-3p CAMK2A -0.57 2.0E-5 -0.33 0.35691 MirTarget -0.36 0.00584 NA
40 hsa-miR-10b-3p CAMK2B 2.77 0 -3.79 0 mirMAP -0.45 0 NA
41 hsa-miR-10b-5p CAMK2B 2.87 0 -3.79 0 miRNATAP -0.42 0 NA
42 hsa-miR-140-3p CAMK2B 0.55 0 -3.79 0 mirMAP -1.81 0 NA
43 hsa-miR-186-5p CAMK2B -0.06 0.53529 -3.79 0 miRNAWalker2 validate; miRNATAP -0.97 5.0E-5 NA
44 hsa-miR-18a-5p CAMK2B 0.92 2.0E-5 -3.79 0 mirMAP -0.42 6.0E-5 NA
45 hsa-miR-34a-5p CAMK2B 1.04 0 -3.79 0 mirMAP -0.52 0.00135 NA
46 hsa-miR-589-3p CAMK2B 1.17 0 -3.79 0 MirTarget -0.78 0 NA
47 hsa-miR-185-5p CAMK2D 0.48 0 -0.69 0 miRNATAP -0.23 0 NA
48 hsa-miR-16-5p CAMK2G -0.4 0.0001 0.58 0 miRNAWalker2 validate -0.14 0.00026 NA
49 hsa-miR-195-3p CAMK2G -1.09 0 0.58 0 mirMAP -0.1 0 NA
50 hsa-miR-1976 CAMK2G -0.43 0.00325 0.58 0 MirTarget -0.1 8.0E-5 NA
51 hsa-miR-30e-3p CAMK2G -1.21 0 0.58 0 MirTarget -0.12 0.0001 NA
52 hsa-miR-484 CAMK2G 0.09 0.45398 0.58 0 mirMAP -0.11 0.00151 NA
53 hsa-miR-628-5p CAMK2G -0.71 0 0.58 0 MirTarget; PITA; miRNATAP -0.11 0.00024 NA
54 hsa-miR-106a-5p CCND1 -0.46 0.00972 -0.9 1.0E-5 MirTarget; miRNATAP -0.26 0 NA
55 hsa-miR-106b-5p CCND1 0.65 0 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.43 0 NA
56 hsa-miR-1266-5p CCND1 1.63 0 -0.9 1.0E-5 MirTarget -0.23 0 NA
57 hsa-miR-15b-5p CCND1 0.23 0.08248 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.54 0 NA
58 hsa-miR-16-5p CCND1 -0.4 0.0001 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.31 0.00178 23991964; 22922827; 18483394 At the molecular level our results further revealed that cyclin D1 expression was negatively regulated by miR-16;CCND1 has been found to be a target of miR-15a and miR-16-1 through analysis of complementary sequences between microRNAs and CCND1 mRNA; Moreover the transcription of CCND1 is suppressed by miR-15a and miR-16-1 via direct binding to the CCND1 3'-untranslated region 3'-UTR;Truncation in CCND1 mRNA alters miR 16 1 regulation in mantle cell lymphoma; Furthermore we demonstrated that this truncation alters miR-16-1 binding sites and through the use of reporter constructs we were able to show that miR-16-1 regulates CCND1 mRNA expression; This study introduces the role of miR-16-1 in the regulation of CCND1 in MCL
59 hsa-miR-17-5p CCND1 0.7 2.0E-5 -0.9 1.0E-5 miRNAWalker2 validate; MirTarget; TargetScan; miRNATAP -0.34 0 26431674 Bioinformatics Prediction and In Vitro Analysis Revealed That miR 17 Targets Cyclin D1 mRNA in Triple Negative Breast Cancer Cells; In this study using bioinformatic analyses miR-17 was selected as it targets the 3'UTR of CCND1 gene with the highest score; After lentiviral transduction of miR-17 to the target cells gene expression analysis showed decreased expression of CCND1 gene
60 hsa-miR-186-5p CCND1 -0.06 0.53529 -0.9 1.0E-5 mirMAP -0.32 0.00286 NA
61 hsa-miR-19a-3p CCND1 1.02 0 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; miRNATAP -0.28 0 25985117 Moreover miR-19a might play inhibitory roles in HCC malignancy via regulating Cyclin D1 expression
62 hsa-miR-19b-1-5p CCND1 -0.28 0.07831 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase -0.31 0 NA
63 hsa-miR-19b-3p CCND1 0.6 0.00017 -0.9 1.0E-5 miRNATAP -0.34 0 NA
64 hsa-miR-20a-5p CCND1 0.85 0 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.33 0 NA
65 hsa-miR-20b-5p CCND1 0.46 0.02859 -0.9 1.0E-5 MirTarget; miRNATAP -0.23 0 NA
66 hsa-miR-340-5p CCND1 -0 0.9685 -0.9 1.0E-5 mirMAP -0.32 0.00013 NA
67 hsa-miR-425-5p CCND1 0.59 2.0E-5 -0.9 1.0E-5 miRNAWalker2 validate -0.39 0 NA
68 hsa-miR-503-5p CCND1 0.19 0.26842 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget -0.16 0.00815 26047605; 23731275 MiR 503 inhibited cell proliferation of human breast cancer cells by suppressing CCND1 expression; Overexpression of miR-503 in breast cancer cell lines reduced cell proliferation through inducing G0/G1 cell cycle arrest by targeting CCND1;MicroRNA 503 suppresses proliferation and cell cycle progression of endometrioid endometrial cancer by negatively regulating cyclin D1; CCND1 has a binding sequence of miR-503 within its 3' untranslated region and was confirmed to be a direct target of miR-503 by the fluorescent reporter assays; Increasing the miR-503 level in EEC cells suppressed cell viability colon formation activity and cell-cycle progression and the inhibited oncogenic phenotypes induced by miR-503 were alleviated by ectopic expression of CCND1 without the untranslated region sequence; Collectively this study suggested that miR-503 plays a tumor-suppressor role by targeting CCND1; Abnormal suppression of miR-503 leads to an increase in the CCND1 level which may promote carcinogenesis and progression of EEC
69 hsa-miR-589-3p CCND1 1.17 0 -0.9 1.0E-5 MirTarget -0.18 0.00124 NA
70 hsa-miR-616-5p CCND1 0.15 0.40284 -0.9 1.0E-5 mirMAP -0.26 1.0E-5 NA
71 hsa-miR-7-1-3p CCND1 -0.57 2.0E-5 -0.9 1.0E-5 mirMAP -0.26 0.00057 NA
72 hsa-miR-9-5p CCND1 1.26 9.0E-5 -0.9 1.0E-5 miRNAWalker2 validate -0.14 1.0E-5 NA
73 hsa-miR-92a-3p CCND1 0.21 0.13429 -0.9 1.0E-5 miRNAWalker2 validate -0.41 0 NA
74 hsa-miR-93-5p CCND1 1.4 0 -0.9 1.0E-5 miRNAWalker2 validate; MirTarget; miRNATAP -0.34 0 NA
75 hsa-miR-942-5p CCND1 0.35 0.02833 -0.9 1.0E-5 MirTarget -0.25 0.00012 NA
76 hsa-miR-130b-5p CCND2 0.17 0.33761 0.36 0.03656 mirMAP -0.17 0.00018 NA
77 hsa-miR-20a-5p CCND2 0.85 0 0.36 0.03656 miRNAWalker2 validate; miRTarBase; miRNATAP -0.16 0.00121 NA
78 hsa-miR-28-5p CCND2 -0.43 0 0.36 0.03656 miRanda -0.48 0 NA
79 hsa-miR-33a-3p CCND2 -0.68 1.0E-5 0.36 0.03656 MirTarget -0.26 0 NA
80 hsa-miR-3607-3p CCND2 -2.16 0 0.36 0.03656 mirMAP -0.12 0.0007 NA
81 hsa-miR-378a-3p CCND2 -1.19 0 0.36 0.03656 miRNAWalker2 validate -0.18 2.0E-5 NA
82 hsa-miR-548v CCND2 -0.27 0.17626 0.36 0.03656 MirTarget -0.15 0.00034 NA
83 hsa-miR-616-5p CCND2 0.15 0.40284 0.36 0.03656 mirMAP -0.32 0 NA
84 hsa-miR-618 CCND2 0.14 0.51715 0.36 0.03656 mirMAP -0.23 0 NA
85 hsa-miR-27b-3p CCND3 -0.82 0 0.08 0.47843 miRNAWalker2 validate -0.24 0 NA
86 hsa-miR-320a CCND3 0.33 0.02214 0.08 0.47843 miRanda -0.12 0.00135 NA
87 hsa-miR-140-5p CHD8 -0.22 0.01407 0.32 0 miRanda -0.1 0.00369 NA
88 hsa-miR-324-3p CREBBP 0.26 0.05061 -0.2 0.01387 miRNAWalker2 validate -0.12 3.0E-5 NA
89 hsa-miR-330-5p CREBBP 0.44 0.00533 -0.2 0.01387 miRanda -0.11 1.0E-5 NA
90 hsa-miR-769-5p CREBBP 0.22 0.03334 -0.2 0.01387 miRNAWalker2 validate -0.13 0.00077 NA
91 hsa-miR-16-1-3p CSNK1A1 0.39 0.00112 -0.34 0 mirMAP -0.12 0 NA
92 hsa-miR-19b-3p CSNK1A1 0.6 0.00017 -0.34 0 mirMAP -0.1 0 NA
93 hsa-miR-21-5p CSNK1A1 1.51 0 -0.34 0 miRNAWalker2 validate -0.1 0 NA
94 hsa-miR-501-3p CSNK1A1 1 0 -0.34 0 TargetScan; miRNATAP -0.1 0 NA
95 hsa-miR-502-3p CSNK1A1 0.66 0 -0.34 0 miRNATAP -0.11 0 NA
96 hsa-miR-148a-5p CSNK1E -0.77 0 0.61 0 miRNATAP -0.25 0 NA
97 hsa-miR-195-3p CSNK1E -1.09 0 0.61 0 miRNATAP -0.1 1.0E-5 NA
98 hsa-let-7c-5p CSNK2A1 -1.71 0 0.31 6.0E-5 miRNAWalker2 validate -0.12 0 NA
99 hsa-miR-125b-5p CSNK2A1 -1.36 0 0.31 6.0E-5 MirTarget; miRNATAP -0.15 0 NA
100 hsa-miR-22-3p CSNK2A1 -0.63 0 0.31 6.0E-5 miRNAWalker2 validate -0.31 0 NA
101 hsa-miR-30c-5p CSNK2A2 -0.43 0.00016 0.07 0.38915 mirMAP -0.11 0.00221 NA
102 hsa-miR-30e-3p CSNK2A2 -1.21 0 0.07 0.38915 mirMAP -0.1 0.00179 NA
103 hsa-miR-146b-5p CTBP2 0.42 0.04574 -0.39 0.02251 miRanda -0.18 1.0E-5 NA
104 hsa-miR-616-5p CTBP2 0.15 0.40284 -0.39 0.02251 mirMAP -0.31 0 NA
105 hsa-miR-618 CTBP2 0.14 0.51715 -0.39 0.02251 MirTarget; PITA -0.33 0 NA
106 hsa-miR-330-3p CTNNB1 -0.33 0.03161 0 0.98356 MirTarget; PITA; miRNATAP -0.13 0 NA
107 hsa-miR-331-3p CTNNB1 -0.28 0.03738 0 0.98356 miRNAWalker2 validate -0.11 0.00027 NA
108 hsa-miR-10a-5p CTNNBIP1 -1.48 0 0.14 0.14796 miRNATAP -0.12 0 NA
109 hsa-miR-23a-3p CTNNBIP1 -0.18 0.13598 0.14 0.14796 MirTarget; miRNATAP -0.19 0 NA
110 hsa-miR-26a-5p CTNNBIP1 -0.96 0 0.14 0.14796 miRNATAP -0.12 0.00775 NA
111 hsa-miR-29a-3p CTNNBIP1 -0.86 0 0.14 0.14796 MirTarget; miRNATAP -0.13 0.00052 NA
112 hsa-miR-92b-3p CTNNBIP1 0.22 0.29619 0.14 0.14796 miRNATAP -0.1 1.0E-5 NA
113 hsa-miR-27a-3p CUL1 -0.37 0.00876 -0.12 0.10228 miRNAWalker2 validate -0.1 4.0E-5 NA
114 hsa-miR-130b-3p DAAM1 0.69 0.00011 -0.82 3.0E-5 MirTarget; miRNATAP -0.23 2.0E-5 NA
115 hsa-miR-181a-5p DAAM1 0.25 0.05519 -0.82 3.0E-5 mirMAP -0.21 0.00568 NA
116 hsa-miR-181b-5p DAAM1 0.49 0.00105 -0.82 3.0E-5 mirMAP -0.24 0.00015 NA
117 hsa-miR-183-5p DAAM1 2.33 0 -0.82 3.0E-5 MirTarget; miRNATAP -0.11 2.0E-5 NA
118 hsa-miR-19a-3p DAAM1 1.02 0 -0.82 3.0E-5 miRNATAP -0.22 0 NA
119 hsa-miR-19b-3p DAAM1 0.6 0.00017 -0.82 3.0E-5 miRNATAP -0.25 3.0E-5 NA
120 hsa-miR-21-5p DAAM1 1.51 0 -0.82 3.0E-5 miRNAWalker2 validate -0.58 0 NA
121 hsa-miR-301a-3p DAAM1 0.84 0 -0.82 3.0E-5 MirTarget; miRNATAP -0.22 5.0E-5 NA
122 hsa-miR-362-3p DAAM1 0.81 0 -0.82 3.0E-5 MirTarget; miRanda; miRNATAP -0.2 0.00452 NA
123 hsa-miR-452-5p DAAM1 1.92 0 -0.82 3.0E-5 MirTarget -0.13 0.00058 NA
124 hsa-miR-500a-3p DAAM1 1.19 0 -0.82 3.0E-5 MirTarget -0.17 0.00798 NA
125 hsa-miR-548j-5p DAAM1 0.25 0.17136 -0.82 3.0E-5 MirTarget -0.2 0.00034 NA
126 hsa-miR-92a-3p DAAM1 0.21 0.13429 -0.82 3.0E-5 miRNATAP -0.33 0 NA
127 hsa-miR-92b-3p DAAM1 0.22 0.29619 -0.82 3.0E-5 miRNATAP -0.19 4.0E-5 NA
128 hsa-miR-182-5p DAAM2 1.97 0 -0.83 6.0E-5 mirMAP -0.15 0 NA
129 hsa-miR-18a-5p DAAM2 0.92 2.0E-5 -0.83 6.0E-5 miRNAWalker2 validate -0.32 0 NA
130 hsa-miR-193a-3p DAAM2 -0.12 0.30939 -0.83 6.0E-5 miRanda -0.34 0.0001 NA
131 hsa-miR-19b-3p DAAM2 0.6 0.00017 -0.83 6.0E-5 miRNAWalker2 validate -0.25 0.0001 NA
132 hsa-miR-339-5p DAAM2 0.28 0.03557 -0.83 6.0E-5 miRanda -0.41 0 NA
133 hsa-miR-421 DAAM2 0.94 0 -0.83 6.0E-5 PITA; miRanda -0.19 0.00111 NA
134 hsa-miR-589-3p DAAM2 1.17 0 -0.83 6.0E-5 mirMAP -0.21 0.00022 NA
135 hsa-miR-29a-3p DKK1 -0.86 0 2.54 1.0E-5 miRNAWalker2 validate; miRTarBase -1.21 0 NA
136 hsa-miR-33a-3p DKK2 -0.68 1.0E-5 0.71 0.03131 mirMAP -0.4 0.00011 NA
137 hsa-miR-3607-3p DKK2 -2.16 0 0.71 0.03131 miRNATAP -0.22 0.00186 NA
138 hsa-miR-361-5p DKK2 0.23 0.00962 0.71 0.03131 miRanda -0.66 0.00028 NA
139 hsa-miR-374a-5p DKK2 0.02 0.86978 0.71 0.03131 mirMAP -0.77 0 NA
140 hsa-miR-374b-5p DKK2 -0.31 0.00301 0.71 0.03131 mirMAP -0.8 0 NA
141 hsa-miR-455-5p DKK2 -0.27 0.05813 0.71 0.03131 miRanda -0.45 6.0E-5 NA
142 hsa-miR-486-5p DKK2 -1.78 0 0.71 0.03131 miRanda; miRNATAP -0.27 4.0E-5 NA
143 hsa-miR-590-3p DKK2 -0.47 2.0E-5 0.71 0.03131 miRanda; mirMAP; miRNATAP -0.51 0.00043 NA
144 hsa-miR-590-5p DKK2 -0.1 0.31003 0.71 0.03131 miRanda -0.74 0 NA
145 hsa-miR-335-5p DKK4 -1.61 0 1.46 0.00691 miRNAWalker2 validate -0.64 0 NA
146 hsa-miR-10a-5p DVL1 -1.48 0 0.1 0.35133 miRNAWalker2 validate -0.12 0 NA
147 hsa-miR-27a-3p DVL2 -0.37 0.00876 0.93 0 miRNATAP -0.1 0.00527 NA
148 hsa-miR-27b-3p DVL2 -0.82 0 0.93 0 miRNATAP -0.22 0 NA
149 hsa-miR-125b-5p DVL3 -1.36 0 0.61 0 miRNATAP -0.13 0 NA
150 hsa-miR-26b-5p DVL3 -1.11 0 0.61 0 miRNAWalker2 validate -0.11 0.00053 NA
NumGOOverlapSizeP ValueAdj. P Value
1 WNT SIGNALING PATHWAY 74 351 2.574e-101 1.198e-97
2 CANONICAL WNT SIGNALING PATHWAY 39 95 8.408e-64 1.956e-60
3 REGULATION OF WNT SIGNALING PATHWAY 48 310 6.538e-56 1.014e-52
4 NON CANONICAL WNT SIGNALING PATHWAY 34 140 3.034e-46 3.529e-43
5 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 35 197 2.04e-42 1.898e-39
6 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 36 236 4.028e-41 3.123e-38
7 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 51 1021 1.998e-34 1.328e-31
8 NEGATIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 28 162 1.752e-33 1.019e-30
9 BETA CATENIN DESTRUCTION COMPLEX DISASSEMBLY 16 22 6.262e-32 3.237e-29
10 POSITIVE REGULATION OF RESPONSE TO STIMULUS 62 1929 7.642e-32 3.556e-29
11 REGULATION OF ORGAN MORPHOGENESIS 30 242 2.419e-31 1.023e-28
12 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 57 1672 3.865e-30 1.499e-27
13 EPITHELIUM DEVELOPMENT 45 945 4.023e-29 1.44e-26
14 POSITIVE REGULATION OF GENE EXPRESSION 56 1733 2.483e-28 8.251e-26
15 TISSUE MORPHOGENESIS 36 533 3.223e-28 9.998e-26
16 NEGATIVE REGULATION OF CELL COMMUNICATION 48 1192 5.735e-28 1.668e-25
17 REGULATION OF PROTEIN MODIFICATION PROCESS 55 1710 1.213e-27 3.321e-25
18 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 52 1492 1.443e-27 3.731e-25
19 TUBE MORPHOGENESIS 30 323 1.594e-27 3.852e-25
20 REGULATION OF EMBRYONIC DEVELOPMENT 22 114 1.656e-27 3.852e-25
21 MORPHOGENESIS OF AN EPITHELIUM 32 400 2.573e-27 5.701e-25
22 POSITIVE REGULATION OF CELL COMMUNICATION 52 1532 5.076e-27 1.074e-24
23 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 49 1360 1.982e-26 4.01e-24
24 WNT SIGNALING PATHWAY CALCIUM MODULATING PATHWAY 16 39 2.914e-26 5.649e-24
25 TISSUE DEVELOPMENT 51 1518 3.164e-26 5.888e-24
26 ORGAN MORPHOGENESIS 40 841 1.174e-25 2.101e-23
27 REGULATION OF CELL DIFFERENTIATION 50 1492 1.346e-25 2.319e-23
28 TUBE DEVELOPMENT 34 552 2.725e-25 4.529e-23
29 REGULATION OF PHOSPHORUS METABOLIC PROCESS 51 1618 6.018e-25 9.656e-23
30 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 53 1805 1.343e-24 2.083e-22
31 REGULATION OF ESTABLISHMENT OF PLANAR POLARITY 20 110 1.65e-24 2.476e-22
32 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 33 554 4.52e-24 6.573e-22
33 EMBRYONIC MORPHOGENESIS 32 539 2.756e-23 3.886e-21
34 EMBRYO DEVELOPMENT 38 894 1.388e-22 1.9e-20
35 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 41 1135 8.255e-22 1.097e-19
36 PATTERN SPECIFICATION PROCESS 28 418 8.885e-22 1.148e-19
37 POSITIVE REGULATION OF MOLECULAR FUNCTION 49 1791 3.569e-21 4.488e-19
38 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 40 1142 9.217e-21 1.129e-18
39 POSITIVE REGULATION OF CELL DIFFERENTIATION 35 823 9.563e-21 1.141e-18
40 REGULATION OF CELLULAR PROTEIN LOCALIZATION 30 552 1.004e-20 1.168e-18
41 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 38 1036 2.335e-20 2.587e-18
42 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 38 1036 2.335e-20 2.587e-18
43 CARDIOVASCULAR SYSTEM DEVELOPMENT 34 788 2.46e-20 2.602e-18
44 CIRCULATORY SYSTEM DEVELOPMENT 34 788 2.46e-20 2.602e-18
45 REGIONALIZATION 24 311 3.782e-20 3.911e-18
46 POSITIVE REGULATION OF WNT SIGNALING PATHWAY 19 152 4.412e-20 4.463e-18
47 REGULATION OF BINDING 23 283 7.715e-20 7.638e-18
48 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 25 365 1.042e-19 1.01e-17
49 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 18 134 1.194e-19 1.134e-17
50 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 36 957 1.328e-19 1.236e-17
51 ANTERIOR POSTERIOR PATTERN SPECIFICATION 20 194 2.141e-19 1.954e-17
52 INTRACELLULAR SIGNAL TRANSDUCTION 44 1572 3.525e-19 3.154e-17
53 NEURON DIFFERENTIATION 34 874 6.184e-19 5.429e-17
54 NEURAL TUBE DEVELOPMENT 18 149 8.501e-19 7.325e-17
55 REGULATION OF CELL CYCLE 35 949 9.026e-19 7.636e-17
56 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 46 1784 1.036e-18 8.609e-17
57 GASTRULATION 18 155 1.755e-18 1.433e-16
58 NEUROGENESIS 41 1402 1.86e-18 1.467e-16
59 TUBE FORMATION 17 129 1.834e-18 1.467e-16
60 DORSAL VENTRAL AXIS SPECIFICATION 10 20 6.643e-18 5.152e-16
61 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 37 1152 6.839e-18 5.216e-16
62 REGULATION OF PROTEIN LOCALIZATION 34 950 7.997e-18 6.002e-16
63 NEURAL TUBE FORMATION 15 94 1.048e-17 7.743e-16
64 REGULATION OF ESTABLISHMENT OF PLANAR POLARITY INVOLVED IN NEURAL TUBE CLOSURE 9 14 1.341e-17 9.751e-16
65 CELL DEVELOPMENT 40 1426 2.381e-17 1.705e-15
66 REGULATION OF TRANSFERASE ACTIVITY 33 946 5.808e-17 4.095e-15
67 REGULATION OF RESPONSE TO STRESS 40 1468 6.494e-17 4.51e-15
68 REGULATION OF CELL DEATH 40 1472 7.132e-17 4.88e-15
69 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 39 1395 7.628e-17 5.144e-15
70 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 42 1656 1.08e-16 7.181e-15
71 SENSORY ORGAN DEVELOPMENT 25 493 1.323e-16 8.672e-15
72 SEGMENTATION 14 89 1.668e-16 1.078e-14
73 REGULATION OF CELLULAR LOCALIZATION 37 1277 1.93e-16 1.23e-14
74 CELL PROLIFERATION 28 672 2.392e-16 1.504e-14
75 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 33 1004 3.319e-16 2.059e-14
76 HEART DEVELOPMENT 24 466 4.111e-16 2.496e-14
77 POSITIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 15 119 4.13e-16 2.496e-14
78 REGULATION OF CELLULAR RESPONSE TO STRESS 28 691 4.867e-16 2.903e-14
79 REGULATION OF CELL PROLIFERATION 39 1496 7.918e-16 4.664e-14
80 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 43 1848 9.241e-16 5.375e-14
81 POSITIVE REGULATION OF CELL DEATH 26 605 1.595e-15 9.164e-14
82 CELL FATE COMMITMENT 18 227 1.664e-15 9.439e-14
83 SOMITOGENESIS 12 62 1.877e-15 1.052e-13
84 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 29 801 2.515e-15 1.393e-13
85 PROTEIN PHOSPHORYLATION 31 944 3.293e-15 1.803e-13
86 SENSORY ORGAN MORPHOGENESIS 18 239 4.112e-15 2.225e-13
87 IMMUNE RESPONSE REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 20 323 4.688e-15 2.507e-13
88 FC EPSILON RECEPTOR SIGNALING PATHWAY 15 142 6.098e-15 3.224e-13
89 POSITIVE REGULATION OF CATALYTIC ACTIVITY 38 1518 7.751e-15 4.052e-13
90 REGULATION OF KINASE ACTIVITY 28 776 9.055e-15 4.682e-13
91 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 21 381 9.19e-15 4.699e-13
92 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 20 337 1.051e-14 5.314e-13
93 MACROMOLECULAR COMPLEX DISASSEMBLY 16 182 1.352e-14 6.762e-13
94 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 17 220 1.644e-14 8.139e-13
95 NEGATIVE REGULATION OF EMBRYONIC DEVELOPMENT 9 26 1.972e-14 9.659e-13
96 REGULATION OF CELL CYCLE PROCESS 24 558 2.235e-14 1.083e-12
97 EMBRYONIC ORGAN DEVELOPMENT 21 406 3.21e-14 1.54e-12
98 REGULATION OF JNK CASCADE 15 159 3.329e-14 1.581e-12
99 SOMITE DEVELOPMENT 12 78 3.486e-14 1.638e-12
100 DOPAMINERGIC NEURON DIFFERENTIATION 9 28 4.316e-14 2.008e-12
101 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 37 1517 4.407e-14 2.01e-12
102 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 15 162 4.399e-14 2.01e-12
103 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 16 197 4.703e-14 2.125e-12
104 REGULATION OF JUN KINASE ACTIVITY 12 81 5.593e-14 2.502e-12
105 BETA CATENIN TCF COMPLEX ASSEMBLY 10 43 6.149e-14 2.725e-12
106 REGULATION OF TRANSPORT 40 1804 6.719e-14 2.949e-12
107 REGULATION OF PROTEIN BINDING 15 168 7.553e-14 3.285e-12
108 REGULATION OF CYTOPLASMIC TRANSPORT 22 481 8.992e-14 3.874e-12
109 NEGATIVE REGULATION OF GENE EXPRESSION 36 1493 1.528e-13 6.523e-12
110 REGULATION OF ORGANELLE ORGANIZATION 32 1178 2.041e-13 8.631e-12
111 AXIS SPECIFICATION 12 90 2.072e-13 8.684e-12
112 REGULATION OF INTRACELLULAR TRANSPORT 24 621 2.283e-13 9.485e-12
113 PROTEIN COMPLEX SUBUNIT ORGANIZATION 36 1527 2.994e-13 1.233e-11
114 REGULATION OF PROTEIN TARGETING 18 307 3.11e-13 1.269e-11
115 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 22 513 3.287e-13 1.33e-11
116 REGULATION OF CELL DEVELOPMENT 27 836 4.152e-13 1.666e-11
117 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 16 228 4.569e-13 1.817e-11
118 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 21 470 5.503e-13 2.17e-11
119 CELL DEATH 29 1001 7.225e-13 2.825e-11
120 CONVERGENT EXTENSION 7 14 7.322e-13 2.839e-11
121 NEGATIVE REGULATION OF MOLECULAR FUNCTION 30 1079 7.621e-13 2.931e-11
122 EMBRYONIC ORGAN MORPHOGENESIS 17 279 8.031e-13 3.063e-11
123 REGULATION OF HYDROLASE ACTIVITY 33 1327 9.048e-13 3.423e-11
124 MORPHOGENESIS OF A BRANCHING STRUCTURE 14 167 1.279e-12 4.8e-11
125 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 40 1977 1.309e-12 4.874e-11
126 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 25 740 1.329e-12 4.908e-11
127 REGULATION OF CELL MORPHOGENESIS 22 552 1.415e-12 5.183e-11
128 FC RECEPTOR SIGNALING PATHWAY 15 206 1.508e-12 5.48e-11
129 REGULATION OF PROTEIN CATABOLIC PROCESS 19 393 1.984e-12 7.156e-11
130 RHYTHMIC PROCESS 17 298 2.317e-12 8.295e-11
131 REGULATION OF CATENIN IMPORT INTO NUCLEUS 8 27 2.5e-12 8.879e-11
132 RESPONSE TO OXYGEN CONTAINING COMPOUND 33 1381 2.696e-12 9.504e-11
133 CELLULAR COMPONENT DISASSEMBLY 21 515 3.152e-12 1.103e-10
134 REGULATION OF STEM CELL DIFFERENTIATION 12 113 3.334e-12 1.158e-10
135 PHOSPHORYLATION 31 1228 3.597e-12 1.24e-10
136 POSITIVE REGULATION OF JUN KINASE ACTIVITY 10 63 3.711e-12 1.27e-10
137 HEAD DEVELOPMENT 24 709 3.845e-12 1.306e-10
138 CELL CYCLE 32 1316 3.988e-12 1.345e-10
139 REGULATION OF PROTEIN IMPORT 14 183 4.474e-12 1.498e-10
140 CELL CYCLE PROCESS 29 1081 4.808e-12 1.598e-10
141 CELLULAR RESPONSE TO RETINOIC ACID 10 65 5.147e-12 1.698e-10
142 MIDBRAIN DEVELOPMENT 11 90 5.79e-12 1.897e-10
143 REGULATION OF MAPK CASCADE 23 660 6.413e-12 2.087e-10
144 DORSAL VENTRAL PATTERN FORMATION 11 91 6.554e-12 2.118e-10
145 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 25 799 7.077e-12 2.271e-10
146 MESENCHYME DEVELOPMENT 14 190 7.452e-12 2.375e-10
147 DIGESTIVE TRACT MORPHOGENESIS 9 48 9.491e-12 3.004e-10
148 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 22 616 1.219e-11 3.832e-10
149 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 24 750 1.249e-11 3.9e-10
150 POSITIVE REGULATION OF CELL CYCLE 17 332 1.293e-11 4.012e-10
151 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 27 983 1.78e-11 5.486e-10
152 NEGATIVE REGULATION OF BINDING 12 131 1.958e-11 5.954e-10
153 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 12 131 1.958e-11 5.954e-10
154 CELL ACTIVATION 21 568 1.99e-11 6.012e-10
155 REGULATION OF IMMUNE SYSTEM PROCESS 32 1403 2.142e-11 6.432e-10
156 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 21 573 2.343e-11 6.988e-10
157 COCHLEA MORPHOGENESIS 7 21 2.397e-11 7.103e-10
158 CELLULAR RESPONSE TO LIPID 19 457 2.725e-11 8.026e-10
159 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 12 135 2.798e-11 8.187e-10
160 HEART MORPHOGENESIS 14 212 3.265e-11 9.495e-10
161 REPRODUCTIVE SYSTEM DEVELOPMENT 18 408 3.62e-11 1.046e-09
162 POSITIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 15 258 3.803e-11 1.092e-09
163 NEGATIVE REGULATION OF PROTEIN BINDING 10 79 3.864e-11 1.103e-09
164 RESPONSE TO RETINOIC ACID 11 107 3.963e-11 1.124e-09
165 EPITHELIAL TO MESENCHYMAL TRANSITION 9 56 4.12e-11 1.155e-09
166 REGULATION OF MITOTIC CELL CYCLE 19 468 4.097e-11 1.155e-09
167 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 17 360 4.618e-11 1.287e-09
168 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 14 218 4.743e-11 1.306e-09
169 POSITIVE REGULATION OF CELL DEVELOPMENT 19 472 4.739e-11 1.306e-09
170 POSITIVE REGULATION OF PROTEIN CATABOLIC PROCESS 15 263 4.988e-11 1.358e-09
171 REGULATION OF CATABOLIC PROCESS 23 731 4.989e-11 1.358e-09
172 RESPONSE TO GROWTH FACTOR 19 475 5.28e-11 1.428e-09
173 FORMATION OF PRIMARY GERM LAYER 11 110 5.372e-11 1.445e-09
174 REGULATION OF OSTEOBLAST DIFFERENTIATION 11 112 6.547e-11 1.751e-09
175 RESPONSE TO LIPID 25 888 6.791e-11 1.806e-09
176 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 17 370 7.081e-11 1.872e-09
177 NEGATIVE REGULATION OF CELL DIFFERENTIATION 21 609 7.247e-11 1.905e-09
178 PROTEASOMAL PROTEIN CATABOLIC PROCESS 15 271 7.609e-11 1.989e-09
179 MUSCLE STRUCTURE DEVELOPMENT 18 432 9.207e-11 2.393e-09
180 STEM CELL DIFFERENTIATION 13 190 1.102e-10 2.849e-09
181 MITOTIC CELL CYCLE 23 766 1.259e-10 3.237e-09
182 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 15 282 1.33e-10 3.4e-09
183 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 11 121 1.523e-10 3.873e-09
184 INNER EAR MORPHOGENESIS 10 92 1.813e-10 4.584e-09
185 MESODERM MORPHOGENESIS 9 66 1.916e-10 4.792e-09
186 REGULATION OF PROTEOLYSIS 22 711 1.913e-10 4.792e-09
187 GLAND DEVELOPMENT 17 395 1.95e-10 4.853e-09
188 REGULATION OF IMMUNE RESPONSE 24 858 1.985e-10 4.914e-09
189 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 19 514 2.013e-10 4.956e-09
190 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 9 67 2.202e-10 5.392e-09
191 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 17 404 2.759e-10 6.687e-09
192 CENTRAL NERVOUS SYSTEM DEVELOPMENT 24 872 2.754e-10 6.687e-09
193 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 24 876 3.021e-10 7.283e-09
194 POSITIVE REGULATION OF CELL PROLIFERATION 23 814 4.136e-10 9.921e-09
195 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 12 171 4.449e-10 1.062e-08
196 POSITIVE REGULATION OF PROTEOLYSIS 16 363 4.923e-10 1.163e-08
197 REGULATION OF APOPTOTIC SIGNALING PATHWAY 16 363 4.923e-10 1.163e-08
198 POSITIVE REGULATION OF KINASE ACTIVITY 18 482 5.381e-10 1.261e-08
199 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 8 50 5.395e-10 1.261e-08
200 IMMUNE SYSTEM PROCESS 36 1984 5.491e-10 1.277e-08
201 STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 10 103 5.615e-10 1.3e-08
202 REGULATION OF OSSIFICATION 12 178 7.065e-10 1.627e-08
203 REGULATION OF MAP KINASE ACTIVITY 15 319 7.364e-10 1.688e-08
204 REGULATION OF FAT CELL DIFFERENTIATION 10 106 7.47e-10 1.704e-08
205 REGULATION OF CELLULAR COMPONENT BIOGENESIS 22 767 7.948e-10 1.804e-08
206 MAMMARY GLAND EPITHELIUM DEVELOPMENT 8 53 8.776e-10 1.973e-08
207 REGULATION OF CELLULAR COMPONENT MOVEMENT 22 771 8.756e-10 1.973e-08
208 REGULATION OF CELL ADHESION 20 629 8.895e-10 1.99e-08
209 REGULATION OF GROWTH 20 633 9.924e-10 2.204e-08
210 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 11 144 9.949e-10 2.204e-08
211 POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 7 34 1.04e-09 2.294e-08
212 EAR MORPHOGENESIS 10 112 1.288e-09 2.827e-08
213 NEGATIVE REGULATION OF CELL PROLIFERATION 20 643 1.3e-09 2.839e-08
214 PEPTIDYL SERINE MODIFICATION 11 148 1.333e-09 2.871e-08
215 DIGESTIVE SYSTEM DEVELOPMENT 11 148 1.333e-09 2.871e-08
216 RESPONSE TO ABIOTIC STIMULUS 25 1024 1.32e-09 2.871e-08
217 OUTFLOW TRACT MORPHOGENESIS 8 56 1.386e-09 2.971e-08
218 REGULATION OF CELL GROWTH 16 391 1.444e-09 3.081e-08
219 NEGATIVE REGULATION OF CELL DEATH 23 872 1.56e-09 3.315e-08
220 SINGLE ORGANISM CELL ADHESION 17 459 1.924e-09 4.051e-08
221 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 14 289 1.923e-09 4.051e-08
222 MAMMARY GLAND DEVELOPMENT 10 117 1.98e-09 4.151e-08
223 MESODERM DEVELOPMENT 10 118 2.153e-09 4.492e-08
224 STEM CELL PROLIFERATION 8 60 2.447e-09 5.061e-08
225 REGULATION OF PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 8 60 2.447e-09 5.061e-08
226 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 16 406 2.478e-09 5.101e-08
227 VASCULATURE DEVELOPMENT 17 469 2.66e-09 5.452e-08
228 POSITIVE REGULATION OF MAPK CASCADE 17 470 2.746e-09 5.604e-08
229 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 19 602 2.78e-09 5.648e-08
230 CELLULAR COMPONENT MORPHOGENESIS 23 900 2.85e-09 5.766e-08
231 COCHLEA DEVELOPMENT 7 39 2.902e-09 5.846e-08
232 UROGENITAL SYSTEM DEVELOPMENT 14 299 2.979e-09 5.975e-08
233 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 20 684 3.737e-09 7.462e-08
234 CELL CYCLE PHASE TRANSITION 13 255 4.081e-09 8.116e-08
235 REGULATION OF PROTEIN PHOSPHATASE TYPE 2A ACTIVITY 6 24 4.818e-09 9.541e-08
236 NEGATIVE REGULATION OF CELL GROWTH 11 170 5.77e-09 1.138e-07
237 RESPONSE TO DRUG 16 431 5.801e-09 1.139e-07
238 CELLULAR RESPONSE TO ABIOTIC STIMULUS 13 263 5.918e-09 1.157e-07
239 POSITIVE REGULATION OF TRANSPORT 23 936 5.98e-09 1.164e-07
240 CELLULAR RESPONSE TO EXTERNAL STIMULUS 13 264 6.193e-09 1.201e-07
241 CELLULAR RESPONSE TO STRESS 30 1565 6.552e-09 1.265e-07
242 REGULATION OF CELL JUNCTION ASSEMBLY 8 68 6.796e-09 1.307e-07
243 REGULATION OF CELL SUBSTRATE ADHESION 11 173 6.931e-09 1.327e-07
244 REGULATION OF CELL CYCLE PHASE TRANSITION 14 321 7.376e-09 1.407e-07
245 MESENCHYMAL CELL DIFFERENTIATION 10 134 7.44e-09 1.413e-07
246 CELLULAR RESPONSE TO ACID CHEMICAL 11 175 7.817e-09 1.478e-07
247 REGULATION OF CELL FATE SPECIFICATION 5 13 8.489e-09 1.599e-07
248 EYE DEVELOPMENT 14 326 8.974e-09 1.684e-07
249 REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 13 274 9.663e-09 1.806e-07
250 PEPTIDYL THREONINE MODIFICATION 7 46 9.758e-09 1.816e-07
251 PROTEIN COMPLEX BIOGENESIS 25 1132 9.994e-09 1.845e-07
252 PROTEIN COMPLEX ASSEMBLY 25 1132 9.994e-09 1.845e-07
253 IMMUNE SYSTEM DEVELOPMENT 18 582 1.04e-08 1.906e-07
254 DEVELOPMENTAL INDUCTION 6 27 1.044e-08 1.906e-07
255 AXIS ELONGATION 6 27 1.044e-08 1.906e-07
256 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 12 229 1.228e-08 2.233e-07
257 POSITIVE REGULATION OF CATABOLIC PROCESS 15 395 1.333e-08 2.413e-07
258 INNATE IMMUNE RESPONSE ACTIVATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 9 106 1.394e-08 2.513e-07
259 REGULATION OF EPITHELIAL CELL PROLIFERATION 13 285 1.544e-08 2.773e-07
260 NEGATIVE REGULATION OF GROWTH 12 236 1.718e-08 3.075e-07
261 REGULATION OF MESODERM DEVELOPMENT 5 15 1.962e-08 3.498e-07
262 RESPONSE TO ENDOGENOUS STIMULUS 28 1450 2.029e-08 3.603e-07
263 RESPIRATORY SYSTEM DEVELOPMENT 11 197 2.673e-08 4.73e-07
264 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 10 154 2.834e-08 4.96e-07
265 FOREBRAIN DEVELOPMENT 14 357 2.815e-08 4.96e-07
266 POSITIVE REGULATION OF CELL CYCLE PROCESS 12 247 2.846e-08 4.96e-07
267 PARAXIAL MESODERM DEVELOPMENT 5 16 2.84e-08 4.96e-07
268 KIDNEY MORPHOGENESIS 8 82 3.058e-08 5.309e-07
269 REGULATION OF ORGAN FORMATION 6 32 3.121e-08 5.398e-07
270 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 9 117 3.319e-08 5.719e-07
271 REPRODUCTION 26 1297 3.446e-08 5.917e-07
272 POSITIVE REGULATION OF EMBRYONIC DEVELOPMENT 6 33 3.796e-08 6.493e-07
273 REGULATION OF CHROMATIN BINDING 5 17 4.005e-08 6.826e-07
274 LEUKOCYTE CELL CELL ADHESION 12 255 4.045e-08 6.869e-07
275 PALATE DEVELOPMENT 8 85 4.068e-08 6.883e-07
276 IN UTERO EMBRYONIC DEVELOPMENT 13 311 4.322e-08 7.286e-07
277 POSITIVE REGULATION OF MAP KINASE ACTIVITY 11 207 4.447e-08 7.47e-07
278 NEGATIVE REGULATION OF CELL CYCLE 15 433 4.486e-08 7.509e-07
279 REGULATION OF MESENCHYMAL CELL PROLIFERATION 6 34 4.587e-08 7.622e-07
280 BRAIN MORPHOGENESIS 6 34 4.587e-08 7.622e-07
281 EMBRYONIC PATTERN SPECIFICATION 7 58 5.168e-08 8.558e-07
282 REGULATION OF STEM CELL PROLIFERATION 8 88 5.353e-08 8.833e-07
283 POST ANAL TAIL MORPHOGENESIS 5 18 5.519e-08 9.042e-07
284 INOSITOL PHOSPHATE MEDIATED SIGNALING 5 18 5.519e-08 9.042e-07
285 RESPONSE TO ACID CHEMICAL 13 319 5.816e-08 9.495e-07
286 KIDNEY EPITHELIUM DEVELOPMENT 9 125 5.905e-08 9.607e-07
287 MESONEPHROS DEVELOPMENT 8 90 6.392e-08 1.036e-06
288 APPENDAGE DEVELOPMENT 10 169 6.845e-08 1.102e-06
289 LIMB DEVELOPMENT 10 169 6.845e-08 1.102e-06
290 REGULATION OF PHOSPHATASE ACTIVITY 9 128 7.253e-08 1.164e-06
291 EMBRYONIC DIGIT MORPHOGENESIS 7 61 7.39e-08 1.182e-06
292 REGULATION OF NON CANONICAL WNT SIGNALING PATHWAY 5 19 7.454e-08 1.188e-06
293 POSITIVE REGULATION OF HYDROLASE ACTIVITY 21 905 7.998e-08 1.27e-06
294 MESENCHYME MORPHOGENESIS 6 38 9.234e-08 1.461e-06
295 REGULATION OF MUSCLE ADAPTATION 7 63 9.28e-08 1.464e-06
296 DEVELOPMENTAL GROWTH 13 333 9.583e-08 1.506e-06
297 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 22 1008 1.095e-07 1.715e-06
298 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 15 465 1.135e-07 1.772e-06
299 EYE MORPHOGENESIS 9 136 1.224e-07 1.905e-06
300 REGULATION OF MEIOTIC CELL CYCLE 6 40 1.272e-07 1.966e-06
301 POSITIVE REGULATION OF CELL MATRIX ADHESION 6 40 1.272e-07 1.966e-06
302 LENS DEVELOPMENT IN CAMERA TYPE EYE 7 66 1.287e-07 1.983e-06
303 POSITIVE REGULATION OF ADHERENS JUNCTION ORGANIZATION 5 21 1.292e-07 1.984e-06
304 LYMPHOCYTE ACTIVATION 13 342 1.304e-07 1.99e-06
305 REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS 10 181 1.304e-07 1.99e-06
306 CELL CELL SIGNALING 19 767 1.32e-07 2.007e-06
307 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 16 541 1.358e-07 2.051e-06
308 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 16 541 1.358e-07 2.051e-06
309 LOCOMOTION 23 1114 1.458e-07 2.196e-06
310 MACROMOLECULAR COMPLEX ASSEMBLY 26 1398 1.527e-07 2.292e-06
311 BIOLOGICAL ADHESION 22 1032 1.645e-07 2.461e-06
312 LEUKOCYTE ACTIVATION 14 414 1.75e-07 2.61e-06
313 MUSCLE CELL DIFFERENTIATION 11 237 1.758e-07 2.613e-06
314 REGULATION OF MUSCLE TISSUE DEVELOPMENT 8 103 1.839e-07 2.699e-06
315 REGULATION OF CIRCADIAN RHYTHM 8 103 1.839e-07 2.699e-06
316 POSITIVE REGULATION OF GROWTH 11 238 1.834e-07 2.699e-06
317 REGULATION OF MUSCLE ORGAN DEVELOPMENT 8 103 1.839e-07 2.699e-06
318 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 20 867 1.869e-07 2.735e-06
319 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 8 104 1.982e-07 2.891e-06
320 SCF DEPENDENT PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 5 23 2.116e-07 3.077e-06
321 RESPONSE TO CYTOKINE 18 714 2.268e-07 3.287e-06
322 FAT CELL DIFFERENTIATION 8 106 2.298e-07 3.321e-06
323 EPITHELIAL CELL DIFFERENTIATION 15 495 2.535e-07 3.652e-06
324 EAR DEVELOPMENT 10 195 2.61e-07 3.749e-06
325 POSITIVE REGULATION OF CELL JUNCTION ASSEMBLY 5 24 2.661e-07 3.807e-06
326 BLOOD VESSEL MORPHOGENESIS 13 364 2.667e-07 3.807e-06
327 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 18 724 2.782e-07 3.959e-06
328 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 10 199 3.15e-07 4.469e-06
329 REGULATION OF CELLULAR RESPONSE TO HEAT 7 76 3.44e-07 4.866e-06
330 REGULATION OF BMP SIGNALING PATHWAY 7 77 3.766e-07 5.31e-06
331 POSITIVE REGULATION OF NON CANONICAL WNT SIGNALING PATHWAY 4 11 3.807e-07 5.352e-06
332 POSITIVE REGULATION OF CELL ADHESION 13 376 3.858e-07 5.406e-06
333 ANTERIOR POSTERIOR AXIS SPECIFICATION 6 48 3.911e-07 5.464e-06
334 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 22 1087 3.996e-07 5.567e-06
335 REGULATION OF CELL FATE COMMITMENT 5 26 4.079e-07 5.665e-06
336 REGULATION OF DEPHOSPHORYLATION 9 158 4.396e-07 6.088e-06
337 RESPONSE TO ORGANIC CYCLIC COMPOUND 20 917 4.55e-07 6.282e-06
338 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 5 27 4.982e-07 6.859e-06
339 REGULATION OF ADHERENS JUNCTION ORGANIZATION 6 50 5.015e-07 6.884e-06
340 REGULATION OF FIBROBLAST PROLIFERATION 7 81 5.34e-07 7.308e-06
341 SKELETAL SYSTEM DEVELOPMENT 14 455 5.466e-07 7.458e-06
342 SEX DIFFERENTIATION 11 266 5.56e-07 7.564e-06
343 POSITIVE REGULATION OF FAT CELL DIFFERENTIATION 6 51 5.656e-07 7.673e-06
344 GASTRULATION WITH MOUTH FORMING SECOND 5 28 6.036e-07 8.165e-06
345 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 8 121 6.367e-07 8.587e-06
346 CELL CELL ADHESION 16 608 6.475e-07 8.707e-06
347 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 9 166 6.666e-07 8.939e-06
348 POSITIVE REGULATION OF OSSIFICATION 7 84 6.854e-07 9.164e-06
349 POSITIVE REGULATION OF MITOCHONDRION ORGANIZATION 9 167 7.011e-07 9.347e-06
350 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 16 616 7.692e-07 1.023e-05
351 WOUND HEALING 14 470 8.042e-07 1.066e-05
352 REGULATION OF BICELLULAR TIGHT JUNCTION ASSEMBLY 4 13 8.173e-07 1.08e-05
353 REGULATION OF PROTEIN STABILITY 10 221 8.248e-07 1.087e-05
354 REGULATION OF CHROMOSOME ORGANIZATION 11 278 8.588e-07 1.129e-05
355 RESPONSE TO UV 8 126 8.671e-07 1.136e-05
356 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION 8 128 9.773e-07 1.277e-05
357 GROWTH 13 410 1.022e-06 1.332e-05
358 REGULATION OF REPRODUCTIVE PROCESS 8 129 1.037e-06 1.348e-05
359 CALCIUM MEDIATED SIGNALING 7 90 1.098e-06 1.419e-05
360 REGULATION OF CELL MATRIX ADHESION 7 90 1.098e-06 1.419e-05
361 PATTERNING OF BLOOD VESSELS 5 32 1.214e-06 1.564e-05
362 REGULATION OF DEVELOPMENTAL GROWTH 11 289 1.256e-06 1.609e-05
363 APOPTOTIC SIGNALING PATHWAY 11 289 1.256e-06 1.609e-05
364 RESPONSE TO WOUNDING 15 563 1.281e-06 1.638e-05
365 NEGATIVE REGULATION OF PHOSPHORYLATION 13 422 1.408e-06 1.795e-05
366 EMBRYONIC AXIS SPECIFICATION 5 33 1.424e-06 1.81e-05
367 ANGIOGENESIS 11 293 1.436e-06 1.82e-05
368 CELLULAR RESPONSE TO RADIATION 8 137 1.634e-06 2.066e-05
369 PROTEIN DESTABILIZATION 5 34 1.661e-06 2.089e-05
370 POSITIVE REGULATION OF STEM CELL PROLIFERATION 6 61 1.662e-06 2.089e-05
371 RESPONSE TO ALCOHOL 12 362 1.721e-06 2.159e-05
372 CELL CYCLE G2 M PHASE TRANSITION 8 138 1.726e-06 2.159e-05
373 REGULATION OF CYTOSKELETON ORGANIZATION 14 502 1.747e-06 2.179e-05
374 PROTEIN CATABOLIC PROCESS 15 579 1.811e-06 2.253e-05
375 REGULATION OF GASTRULATION 5 35 1.929e-06 2.393e-05
376 REGULATION OF EPIDERMIS DEVELOPMENT 6 63 2.014e-06 2.492e-05
377 PROTEIN DEPHOSPHORYLATION 9 190 2.053e-06 2.52e-05
378 APOPTOTIC PROCESS INVOLVED IN MORPHOGENESIS 4 16 2.052e-06 2.52e-05
379 CELL SURFACE RECEPTOR SIGNALING PATHWAY INVOLVED IN HEART DEVELOPMENT 4 16 2.052e-06 2.52e-05
380 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 7 99 2.093e-06 2.563e-05
381 POSITIVE REGULATION OF INNATE IMMUNE RESPONSE 10 246 2.173e-06 2.654e-05
382 RESPONSE TO EXTERNAL STIMULUS 28 1821 2.19e-06 2.667e-05
383 POSITIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 9 192 2.238e-06 2.7e-05
384 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 7 100 2.24e-06 2.7e-05
385 POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 5 36 2.229e-06 2.7e-05
386 PROTEIN AUTOPHOSPHORYLATION 9 192 2.238e-06 2.7e-05
387 CARDIAC CHAMBER DEVELOPMENT 8 144 2.377e-06 2.857e-05
388 PEPTIDYL AMINO ACID MODIFICATION 18 841 2.391e-06 2.864e-05
389 CAMERA TYPE EYE MORPHOGENESIS 7 101 2.395e-06 2.864e-05
390 CONNECTIVE TISSUE DEVELOPMENT 9 194 2.437e-06 2.908e-05
391 RESPONSE TO OXYGEN LEVELS 11 311 2.557e-06 3.037e-05
392 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 7 102 2.559e-06 3.037e-05
393 CELLULAR RESPONSE TO UV 6 66 2.654e-06 3.134e-05
394 FOREBRAIN GENERATION OF NEURONS 6 66 2.654e-06 3.134e-05
395 ESTABLISHMENT OF TISSUE POLARITY 4 17 2.671e-06 3.138e-05
396 REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 4 17 2.671e-06 3.138e-05
397 REGULATION OF PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 8 148 2.917e-06 3.385e-05
398 CARDIAC CHAMBER MORPHOGENESIS 7 104 2.915e-06 3.385e-05
399 POSITIVE REGULATION OF CELL GROWTH 8 148 2.917e-06 3.385e-05
400 POSITIVE REGULATION OF PROTEIN IMPORT 7 104 2.915e-06 3.385e-05
401 MALE SEX DIFFERENTIATION 8 148 2.917e-06 3.385e-05
402 REGULATION OF CELL MATURATION 4 18 3.418e-06 3.947e-05
403 PERICARDIUM DEVELOPMENT 4 18 3.418e-06 3.947e-05
404 REGULATION OF MUSCLE CELL DIFFERENTIATION 8 152 3.558e-06 4.098e-05
405 ACTIVATION OF INNATE IMMUNE RESPONSE 9 204 3.68e-06 4.228e-05
406 NEURAL PRECURSOR CELL PROLIFERATION 6 70 3.756e-06 4.284e-05
407 REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 7 108 3.751e-06 4.284e-05
408 REGULATION OF MEMBRANE PERMEABILITY 6 70 3.756e-06 4.284e-05
409 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 10 262 3.812e-06 4.337e-05
410 NEURON PROJECTION GUIDANCE 9 205 3.83e-06 4.347e-05
411 SKIN EPIDERMIS DEVELOPMENT 6 71 4.083e-06 4.611e-05
412 ENDODERM DEVELOPMENT 6 71 4.083e-06 4.611e-05
413 POSITIVE REGULATION OF PROTEIN EXPORT FROM NUCLEUS 4 19 4.31e-06 4.856e-05
414 LYMPHOCYTE DIFFERENTIATION 9 209 4.484e-06 5.039e-05
415 NEURON PROJECTION DEVELOPMENT 14 545 4.524e-06 5.073e-05
416 EMBRYONIC HEART TUBE DEVELOPMENT 6 73 4.807e-06 5.376e-05
417 SKIN DEVELOPMENT 9 211 4.845e-06 5.406e-05
418 NEGATIVE REGULATION OF BMP SIGNALING PATHWAY 5 42 4.889e-06 5.442e-05
419 RESPONSE TO METAL ION 11 333 4.92e-06 5.464e-05
420 SECOND MESSENGER MEDIATED SIGNALING 8 160 5.205e-06 5.767e-05
421 REGULATION OF CELL DIVISION 10 272 5.31e-06 5.868e-05
422 TRACHEA DEVELOPMENT 4 20 5.363e-06 5.885e-05
423 POSITIVE REGULATION OF GLYCOPROTEIN METABOLIC PROCESS 4 20 5.363e-06 5.885e-05
424 BRANCHING INVOLVED IN MAMMARY GLAND DUCT MORPHOGENESIS 4 20 5.363e-06 5.885e-05
425 REGULATION OF NEURON DIFFERENTIATION 14 554 5.457e-06 5.974e-05
426 REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 5 43 5.506e-06 5.986e-05
427 MORPHOGENESIS OF AN EPITHELIAL SHEET 5 43 5.506e-06 5.986e-05
428 REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 5 43 5.506e-06 5.986e-05
429 RESPONSE TO INORGANIC SUBSTANCE 13 479 5.631e-06 6.107e-05
430 NEPHRON DEVELOPMENT 7 115 5.696e-06 6.164e-05
431 LABYRINTHINE LAYER DEVELOPMENT 5 44 6.182e-06 6.659e-05
432 BRANCHING INVOLVED IN URETERIC BUD MORPHOGENESIS 5 44 6.182e-06 6.659e-05
433 REGULATION OF MITOCHONDRION ORGANIZATION 9 218 6.313e-06 6.784e-05
434 SPECIFICATION OF SYMMETRY 7 117 6.385e-06 6.846e-05
435 REGULATION OF CYTOKINE PRODUCTION 14 563 6.556e-06 6.992e-05
436 REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 6 77 6.566e-06 6.992e-05
437 POSITIVE REGULATION OF IMMUNE RESPONSE 14 563 6.556e-06 6.992e-05
438 APOPTOTIC PROCESS INVOLVED IN DEVELOPMENT 4 21 6.594e-06 7.005e-05
439 RESPONSE TO RADIATION 12 413 6.646e-06 7.044e-05
440 THYMOCYTE AGGREGATION 5 45 6.922e-06 7.304e-05
441 T CELL DIFFERENTIATION IN THYMUS 5 45 6.922e-06 7.304e-05
442 RENAL TUBULE DEVELOPMENT 6 78 7.079e-06 7.452e-05
443 SOMATIC STEM CELL DIVISION 4 22 8.022e-06 8.426e-05
444 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 17 829 8.248e-06 8.644e-05
445 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 7 122 8.415e-06 8.799e-05
446 T CELL DIFFERENTIATION 7 123 8.88e-06 9.264e-05
447 ACTIVATION OF IMMUNE RESPONSE 12 427 9.297e-06 9.678e-05
448 JNK CASCADE 6 82 9.466e-06 9.832e-05
449 LEUKOCYTE DIFFERENTIATION 10 292 9.888e-06 0.0001025
450 HAIR CYCLE 6 83 1.015e-05 0.0001048
451 MOLTING CYCLE 6 83 1.015e-05 0.0001048
452 OSTEOBLAST DIFFERENTIATION 7 126 1.04e-05 0.0001068
453 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 7 126 1.04e-05 0.0001068
454 CARDIAC SEPTUM MORPHOGENESIS 5 49 1.06e-05 0.0001086
455 REGULATION OF VASCULATURE DEVELOPMENT 9 233 1.078e-05 0.0001103
456 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 6 84 1.088e-05 0.000111
457 REGULATION OF GTPASE ACTIVITY 15 673 1.113e-05 0.0001134
458 HEPATICOBILIARY SYSTEM DEVELOPMENT 7 128 1.153e-05 0.0001172
459 CARDIAC SEPTUM DEVELOPMENT 6 85 1.165e-05 0.0001181
460 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 7 129 1.213e-05 0.0001227
461 RESPONSE TO NITROGEN COMPOUND 17 859 1.309e-05 0.0001321
462 POSITIVE REGULATION OF CYTOKINE PRODUCTION 11 370 1.326e-05 0.0001336
463 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 10 303 1.363e-05 0.000137
464 MAINTENANCE OF CELL NUMBER 7 132 1.41e-05 0.0001414
465 NEURON DEVELOPMENT 15 687 1.419e-05 0.000142
466 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 5 53 1.565e-05 0.0001557
467 EPITHELIAL CELL DEVELOPMENT 8 186 1.566e-05 0.0001557
468 MESONEPHRIC TUBULE MORPHOGENESIS 5 53 1.565e-05 0.0001557
469 DEVELOPMENTAL PROGRAMMED CELL DEATH 4 26 1.61e-05 0.0001597
470 CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS 8 188 1.692e-05 0.0001675
471 CELLULAR RESPONSE TO LIGHT STIMULUS 6 91 1.725e-05 0.0001704
472 REGULATION OF ACTIN FILAMENT BASED PROCESS 10 312 1.754e-05 0.0001729
473 MITOCHONDRIAL MEMBRANE ORGANIZATION 6 92 1.837e-05 0.0001807
474 NEGATIVE REGULATION OF TRANSPORT 12 458 1.867e-05 0.0001833
475 NEGATIVE REGULATION OF KINASE ACTIVITY 9 250 1.889e-05 0.0001835
476 REGULATION OF KIDNEY DEVELOPMENT 5 55 1.88e-05 0.0001835
477 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 21 1275 1.885e-05 0.0001835
478 RESPONSE TO LITHIUM ION 4 27 1.881e-05 0.0001835
479 PLACENTA DEVELOPMENT 7 138 1.882e-05 0.0001835
480 NEPHRON EPITHELIUM DEVELOPMENT 6 93 1.954e-05 0.000189
481 REGULATION OF DNA BINDING 6 93 1.954e-05 0.000189
482 MITOTIC CELL CYCLE CHECKPOINT 7 139 1.972e-05 0.0001904
483 TAXIS 12 464 2.123e-05 0.0002045
484 RESPONSE TO HORMONE 17 893 2.153e-05 0.000207
485 VENTRICULAR SEPTUM MORPHOGENESIS 4 28 2.184e-05 0.0002087
486 MORPHOGENESIS OF A POLARIZED EPITHELIUM 4 28 2.184e-05 0.0002087
487 MAMMARY GLAND DUCT MORPHOGENESIS 4 28 2.184e-05 0.0002087
488 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 6 95 2.206e-05 0.00021
489 REGULATION OF MUSCLE SYSTEM PROCESS 8 195 2.202e-05 0.00021
490 POSITIVE REGULATION OF PROTEIN COMPLEX ASSEMBLY 8 197 2.37e-05 0.000225
491 CELL PROJECTION ORGANIZATION 17 902 2.445e-05 0.0002317
492 REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 4 29 2.522e-05 0.0002371
493 POSITIVE REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 4 29 2.522e-05 0.0002371
494 STEM CELL DIVISION 4 29 2.522e-05 0.0002371
495 REGULATION OF HEART MORPHOGENESIS 4 29 2.522e-05 0.0002371
496 SYNAPSE ORGANIZATION 7 145 2.591e-05 0.0002431
497 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 7 146 2.709e-05 0.0002536
498 SKELETAL SYSTEM MORPHOGENESIS 8 201 2.737e-05 0.0002557
499 NEGATIVE REGULATION OF LOCOMOTION 9 263 2.815e-05 0.0002625
500 CARTILAGE DEVELOPMENT 7 147 2.83e-05 0.0002629
501 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 7 147 2.83e-05 0.0002629
502 PROTEOLYSIS 20 1208 2.848e-05 0.000264
503 CHROMOSOME ORGANIZATION 18 1009 2.855e-05 0.0002641
504 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 5 60 2.882e-05 0.0002661
505 RESPONSE TO X RAY 4 30 2.897e-05 0.0002669
506 REGULATION OF DNA TEMPLATED TRANSCRIPTION INITIATION 4 31 3.311e-05 0.0003045
507 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 8 207 3.376e-05 0.0003092
508 REGULATION OF SMOOTHENED SIGNALING PATHWAY 5 62 3.382e-05 0.0003092
509 EMBRYONIC HEART TUBE MORPHOGENESIS 5 62 3.382e-05 0.0003092
510 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 8 209 3.615e-05 0.0003298
511 PALLIUM DEVELOPMENT 7 153 3.658e-05 0.0003331
512 RESPONSE TO MECHANICAL STIMULUS 8 210 3.74e-05 0.0003399
513 CHROMATIN ORGANIZATION 14 663 4.031e-05 0.0003656
514 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 7 156 4.141e-05 0.0003741
515 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 8 213 4.136e-05 0.0003741
516 POSITIVE REGULATION OF LOCOMOTION 11 420 4.246e-05 0.0003829
517 REGULATION OF PROTEIN EXPORT FROM NUCLEUS 4 33 4.266e-05 0.000384
518 POSITIVE REGULATION BY HOST OF VIRAL TRANSCRIPTION 3 12 4.345e-05 0.0003873
519 TRACHEA MORPHOGENESIS 3 12 4.345e-05 0.0003873
520 POSITIVE REGULATION OF CATENIN IMPORT INTO NUCLEUS 3 12 4.345e-05 0.0003873
521 MAMMARY GLAND EPITHELIAL CELL PROLIFERATION 3 12 4.345e-05 0.0003873
522 REGULATION OF WNT SIGNALING PATHWAY PLANAR CELL POLARITY PATHWAY 3 12 4.345e-05 0.0003873
523 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 8 216 4.566e-05 0.0004062
524 SOMATIC STEM CELL POPULATION MAINTENANCE 5 66 4.584e-05 0.0004065
525 RESPONSE TO LIGHT STIMULUS 9 280 4.587e-05 0.0004065
526 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 10 351 4.77e-05 0.000422
527 REGULATION OF PROTEIN DEACETYLATION 4 34 4.813e-05 0.000425
528 REGULATION OF DNA TEMPLATED TRANSCRIPTION IN RESPONSE TO STRESS 5 67 4.93e-05 0.0004336
529 REGULATION OF SISTER CHROMATID SEGREGATION 5 67 4.93e-05 0.0004336
530 PROTEIN LOCALIZATION 25 1805 5.069e-05 0.000445
531 CELL CYCLE G1 S PHASE TRANSITION 6 111 5.321e-05 0.0004654
532 G1 S TRANSITION OF MITOTIC CELL CYCLE 6 111 5.321e-05 0.0004654
533 BONE REMODELING 4 35 5.409e-05 0.0004713
534 DEPHOSPHORYLATION 9 286 5.403e-05 0.0004713
535 REGULATION OF NUCLEAR DIVISION 7 163 5.473e-05 0.0004751
536 CELLULAR RESPONSE TO BIOTIC STIMULUS 7 163 5.473e-05 0.0004751
537 REGULATION OF INNATE IMMUNE RESPONSE 10 357 5.498e-05 0.0004764
538 HEMATOPOIETIC STEM CELL PROLIFERATION 3 13 5.624e-05 0.0004855
539 REGULATION OF SKELETAL MUSCLE ADAPTATION 3 13 5.624e-05 0.0004855
540 SYNAPSE ASSEMBLY 5 69 5.683e-05 0.0004897
541 HEAD MORPHOGENESIS 4 36 6.058e-05 0.000521
542 MUSCLE ORGAN MORPHOGENESIS 5 70 6.091e-05 0.0005229
543 CELLULAR RESPONSE TO ALCOHOL 6 115 6.486e-05 0.0005538
544 POSITIVE REGULATION OF DEFENSE RESPONSE 10 364 6.464e-05 0.0005538
545 RESPONSE TO CALCIUM ION 6 115 6.486e-05 0.0005538
546 NEGATIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 5 71 6.522e-05 0.0005558
547 RESPONSE TO EXTRACELLULAR STIMULUS 11 441 6.584e-05 0.00056
548 RESPONSE TO CARBOHYDRATE 7 168 6.625e-05 0.0005626
549 TELENCEPHALON DEVELOPMENT 8 228 6.68e-05 0.0005662
550 REGULATION OF MUSCLE HYPERTROPHY 4 37 6.761e-05 0.000572
551 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 10 368 7.078e-05 0.0005977
552 POSITIVE REGULATION OF MEIOTIC CELL CYCLE 3 14 7.127e-05 0.0005986
553 CELL MIGRATION INVOLVED IN GASTRULATION 3 14 7.127e-05 0.0005986
554 REGULATION OF MONOCYTE DIFFERENTIATION 3 14 7.127e-05 0.0005986
555 POSITIVE REGULATION OF PROTEIN BINDING 5 73 7.453e-05 0.0006237
556 PANCREAS DEVELOPMENT 5 73 7.453e-05 0.0006237
557 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 6 118 7.487e-05 0.0006254
558 G PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY 19 1193 7.783e-05 0.000649
559 REGULATION OF PROTEIN COMPLEX ASSEMBLY 10 375 8.273e-05 0.0006887
560 NEGATIVE REGULATION OF CELL DEVELOPMENT 9 303 8.413e-05 0.000699
561 NEURAL CREST CELL DIFFERENTIATION 5 75 8.483e-05 0.0007036
562 NEGATIVE REGULATION OF DENDRITE MORPHOGENESIS 3 15 8.87e-05 0.0007344
563 CHROMATIN MODIFICATION 12 539 9e-05 0.0007439
564 MAMMARY GLAND MORPHOGENESIS 4 40 9.227e-05 0.0007586
565 MITOCHONDRIAL TRANSPORT 7 177 9.196e-05 0.0007586
566 NEGATIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 4 40 9.227e-05 0.0007586
567 CELL DIVISION 11 460 9.576e-05 0.0007859
568 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 4 41 0.0001018 0.0008338
569 ORGAN INDUCTION 3 16 0.0001087 0.0008888
570 EPITHELIAL CELL MORPHOGENESIS 4 42 0.000112 0.0009125
571 GENITALIA DEVELOPMENT 4 42 0.000112 0.0009125
572 POSITIVE REGULATION OF BINDING 6 127 0.0001125 0.0009149
573 REGULATION OF MYELOID CELL DIFFERENTIATION 7 183 0.0001132 0.0009195
574 CELLULAR RESPONSE TO MECHANICAL STIMULUS 5 80 0.0001154 0.0009355
575 MUSCLE CELL DEVELOPMENT 6 128 0.0001174 0.0009503
576 MACROMOLECULE CATABOLIC PROCESS 16 926 0.0001201 0.0009705
577 CELLULAR MACROMOLECULE LOCALIZATION 19 1234 0.0001213 0.0009784
578 NEGATIVE REGULATION OF STEM CELL DIFFERENTIATION 4 43 0.0001229 0.0009877
579 REGULATION OF GLYCOPROTEIN METABOLIC PROCESS 4 43 0.0001229 0.0009877
580 REGULATION OF CELL PROJECTION ORGANIZATION 12 558 0.0001246 0.0009997
581 CELL MOTILITY 15 835 0.0001304 0.00104
582 LOCALIZATION OF CELL 15 835 0.0001304 0.00104
583 OSSIFICATION 8 251 0.0001302 0.00104
584 REGULATION OF NFAT PROTEIN IMPORT INTO NUCLEUS 3 17 0.0001314 0.001045
585 CELLULAR RESPONSE TO LITHIUM ION 3 17 0.0001314 0.001045
586 PROTEIN STABILIZATION 6 131 0.0001334 0.001059
587 REGULATION OF HORMONE LEVELS 11 478 0.0001342 0.001064
588 BODY MORPHOGENESIS 4 44 0.0001346 0.001065
589 EMBRYONIC PLACENTA DEVELOPMENT 5 83 0.0001374 0.001082
590 NIK NF KAPPAB SIGNALING 5 83 0.0001374 0.001082
591 EPIDERMIS DEVELOPMENT 8 253 0.0001375 0.001082
592 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 7 190 0.0001429 0.001123
593 POSITIVE REGULATION OF MUSCLE CELL DIFFERENTIATION 5 84 0.0001454 0.001141
594 NEURON PROJECTION MORPHOGENESIS 10 402 0.0001462 0.001145
595 REGULATION OF STRIATED MUSCLE CELL DIFFERENTIATION 5 85 0.0001538 0.001201
596 REGULATION OF CHROMOSOME SEGREGATION 5 85 0.0001538 0.001201
597 NEGATIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 6 135 0.0001573 0.001224
598 SIGNAL TRANSDUCTION INVOLVED IN REGULATION OF GENE EXPRESSION 3 18 0.000157 0.001224
599 CELL CYCLE CHECKPOINT 7 194 0.0001626 0.001263
600 ANTIGEN RECEPTOR MEDIATED SIGNALING PATHWAY 7 195 0.0001678 0.001301
601 POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS 4 47 0.0001744 0.00135
602 POSITIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 5 88 0.0001811 0.0014
603 REGULATION OF CARDIAC MUSCLE CELL DIFFERENTIATION 3 19 0.0001856 0.001432
604 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 4 48 0.0001894 0.001457
605 POSITIVE REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 4 48 0.0001894 0.001457
606 EPITHELIAL CELL PROLIFERATION 5 89 0.000191 0.001464
607 MULTICELLULAR ORGANISM REPRODUCTION 14 768 0.0001907 0.001464
608 REGULATION OF DNA METABOLIC PROCESS 9 340 0.0002002 0.001532
609 PLATELET ACTIVATION 6 142 0.0002071 0.001582
610 CELLULAR RESPONSE TO OXYGEN LEVELS 6 143 0.0002151 0.001641
611 CELLULAR RESPONSE TO NITROGEN COMPOUND 11 505 0.0002161 0.001645
612 TONGUE DEVELOPMENT 3 20 0.0002175 0.001653
613 REGULATION OF SKELETAL MUSCLE TISSUE DEVELOPMENT 4 50 0.0002221 0.001678
614 FACE DEVELOPMENT 4 50 0.0002221 0.001678
615 ENDODERM FORMATION 4 50 0.0002221 0.001678
616 POSITIVE REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 4 50 0.0002221 0.001678
617 COVALENT CHROMATIN MODIFICATION 9 345 0.0002231 0.001682
618 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 6 144 0.0002234 0.001682
619 BONE RESORPTION 3 21 0.0002526 0.001899
620 MUSCLE ORGAN DEVELOPMENT 8 277 0.0002548 0.001912
621 POSITIVE REGULATION OF REPRODUCTIVE PROCESS 4 52 0.0002587 0.001935
622 NEGATIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 5 95 0.0002591 0.001935
623 REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 5 95 0.0002591 0.001935
624 CELLULAR RESPONSE TO CYTOKINE STIMULUS 12 606 0.0002666 0.001988
625 REGULATION OF SECRETION 13 699 0.0002699 0.002009
626 REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 8 280 0.0002739 0.002036
627 POSITIVE REGULATION OF FIBROBLAST PROLIFERATION 4 53 0.0002786 0.002067
628 GLAND MORPHOGENESIS 5 97 0.0002855 0.002114
629 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 10 437 0.0002858 0.002114
630 MODULATION OF TRANSCRIPTION IN OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 3 22 0.0002912 0.002134
631 POSITIVE REGULATION OF MUSCLE HYPERTROPHY 3 22 0.0002912 0.002134
632 POSITIVE REGULATION OF CARDIAC MUSCLE HYPERTROPHY 3 22 0.0002912 0.002134
633 MEMBRANE ORGANIZATION 15 899 0.0002896 0.002134
634 REGULATION OF STRIATED MUSCLE CELL APOPTOTIC PROCESS 3 22 0.0002912 0.002134
635 EMBRYONIC PLACENTA MORPHOGENESIS 3 22 0.0002912 0.002134
636 NEGATIVE REGULATION OF CELL CYCLE PROCESS 7 214 0.0002961 0.002166
637 NEGATIVE REGULATION OF REPRODUCTIVE PROCESS 4 54 0.0002995 0.002174
638 POSITIVE REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS 5 98 0.0002994 0.002174
639 INTRINSIC APOPTOTIC SIGNALING PATHWAY 6 152 0.000299 0.002174
640 VENTRICULAR SEPTUM DEVELOPMENT 4 54 0.0002995 0.002174
641 REGULATION OF CHROMATIN ORGANIZATION 6 152 0.000299 0.002174
642 CELL CYCLE ARREST 6 154 0.0003207 0.002321
643 AMEBOIDAL TYPE CELL MIGRATION 6 154 0.0003207 0.002321
644 REGULATION OF OSTEOBLAST PROLIFERATION 3 23 0.0003334 0.002409
645 SMAD PROTEIN SIGNAL TRANSDUCTION 4 56 0.0003446 0.002475
646 CELLULAR RESPONSE TO INORGANIC SUBSTANCE 6 156 0.0003437 0.002475
647 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 4 56 0.0003446 0.002475
648 REGULATION OF EXTENT OF CELL GROWTH 5 101 0.0003443 0.002475
649 APOPTOTIC MITOCHONDRIAL CHANGES 4 57 0.000369 0.002645
650 REGULATION OF HISTONE DEACETYLATION 3 24 0.0003794 0.002712
651 POSITIVE REGULATION OF DNA TEMPLATED TRANSCRIPTION INITIATION 3 24 0.0003794 0.002712
652 PROTEIN ACYLATION 6 159 0.0003805 0.002715
653 REGULATION OF DNA REPLICATION 6 161 0.0004067 0.002898
654 CEREBRAL CORTEX DEVELOPMENT 5 105 0.0004119 0.002926
655 ODONTOGENESIS 5 105 0.0004119 0.002926
656 VASCULOGENESIS 4 59 0.0004212 0.002988
657 LENS FIBER CELL DIFFERENTIATION 3 25 0.0004293 0.003017
658 SPINDLE CHECKPOINT 3 25 0.0004293 0.003017
659 FOREBRAIN REGIONALIZATION 3 25 0.0004293 0.003017
660 REGULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 3 25 0.0004293 0.003017
661 NEGATIVE REGULATION OF SMOOTHENED SIGNALING PATHWAY 3 25 0.0004293 0.003017
662 POSITIVE REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION 3 25 0.0004293 0.003017
663 CARDIAC VENTRICLE DEVELOPMENT 5 106 0.0004303 0.00302
664 NEGATIVE REGULATION OF CELL DIVISION 4 60 0.0004493 0.003139
665 CELL SUBSTRATE ADHESION 6 164 0.0004486 0.003139
666 CHONDROCYTE DIFFERENTIATION 4 60 0.0004493 0.003139
667 REGULATION OF CELL CELL ADHESION 9 380 0.0004523 0.003155
668 CELLULAR RESPONSE TO HORMONE STIMULUS 11 552 0.0004595 0.003201
669 REGULATION OF CELL CYCLE ARREST 5 108 0.0004688 0.003261
670 REGULATION OF LEUKOCYTE DIFFERENTIATION 7 232 0.0004812 0.003337
671 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 7 232 0.0004812 0.003337
672 POSITIVE REGULATION OF SKELETAL MUSCLE TISSUE DEVELOPMENT 3 26 0.0004832 0.003346
673 NEGATIVE REGULATION OF PROTEIN CATABOLIC PROCESS 5 109 0.0004891 0.003376
674 RESPONSE TO HYDROGEN PEROXIDE 5 109 0.0004891 0.003376
675 POSITIVE REGULATION OF NUCLEAR DIVISION 4 62 0.0005093 0.003511
676 REGULATION OF CARTILAGE DEVELOPMENT 4 63 0.0005413 0.00371
677 REGULATION OF ENDOTHELIAL CELL DIFFERENTIATION 3 27 0.0005413 0.00371
678 NEGATIVE REGULATION OF FIBROBLAST PROLIFERATION 3 27 0.0005413 0.00371
679 NEGATIVE REGULATION OF AXON GUIDANCE 3 27 0.0005413 0.00371
680 HEMOSTASIS 8 311 0.0005505 0.003767
681 REGULATION OF CELL SIZE 6 172 0.000577 0.003942
682 REGULATION OF DEFENSE RESPONSE 13 759 0.000589 0.004019
683 STRIATED MUSCLE CELL DIFFERENTIATION 6 173 0.0005948 0.004052
684 PLACENTA BLOOD VESSEL DEVELOPMENT 3 28 0.0006036 0.004082
685 NEGATIVE REGULATION OF CHROMOSOME SEGREGATION 3 28 0.0006036 0.004082
686 CELL FATE COMMITMENT INVOLVED IN FORMATION OF PRIMARY GERM LAYER 3 28 0.0006036 0.004082
687 NEGATIVE REGULATION OF DENDRITE DEVELOPMENT 3 28 0.0006036 0.004082
688 METANEPHROS MORPHOGENESIS 3 28 0.0006036 0.004082
689 RESPONSE TO INTERLEUKIN 1 5 115 0.0006246 0.004218
690 POSITIVE REGULATION OF CYTOSKELETON ORGANIZATION 6 175 0.0006318 0.004261
691 REGULATION OF MICROTUBULE BASED PROCESS 7 243 0.0006335 0.004266
692 FEMALE SEX DIFFERENTIATION 5 116 0.0006497 0.004368
693 REGULATION OF MEIOTIC NUCLEAR DIVISION 3 29 0.0006703 0.004494
694 NEUROBLAST PROLIFERATION 3 29 0.0006703 0.004494
695 NEGATIVE REGULATION OF CYTOPLASMIC TRANSPORT 5 117 0.0006755 0.004516
696 CELLULAR RESPONSE TO STARVATION 5 117 0.0006755 0.004516
697 POSITIVE REGULATION OF NEURON DEATH 4 67 0.0006839 0.004559
698 CELLULAR RESPONSE TO DRUG 4 67 0.0006839 0.004559
699 CATABOLIC PROCESS 22 1773 0.0007137 0.004751
700 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 4 68 0.0007234 0.004808
701 REGULATION OF CHEMOTAXIS 6 180 0.0007322 0.00486
702 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE BY P53 CLASS MEDIATOR 3 30 0.0007416 0.004894
703 SMOOTH MUSCLE CELL DIFFERENTIATION 3 30 0.0007416 0.004894
704 POSITIVE REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 3 30 0.0007416 0.004894
705 NEGATIVE REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 3 30 0.0007416 0.004894
706 REGULATION OF NEURON PROJECTION DEVELOPMENT 9 408 0.0007518 0.004955
707 NEGATIVE REGULATION OF OSSIFICATION 4 69 0.0007644 0.005024
708 POSITIVE REGULATION OF AXONOGENESIS 4 69 0.0007644 0.005024
709 RESPONSE TO KETONE 6 182 0.0007757 0.005091
710 RESPONSE TO STEROID HORMONE 10 497 0.0007783 0.0051
711 SYSTEM PROCESS 22 1785 0.0007808 0.00511
712 INTERFERON GAMMA MEDIATED SIGNALING PATHWAY 4 70 0.000807 0.005274
713 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 5 122 0.0008162 0.005319
714 CELLULAR RESPONSE TO INTERFERON GAMMA 5 122 0.0008162 0.005319
715 POSITIVE REGULATION OF MITOTIC CELL CYCLE 5 123 0.0008468 0.005511
716 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE 4 71 0.0008513 0.005525
717 CELL FATE SPECIFICATION 4 71 0.0008513 0.005525
718 REGULATION OF PEPTIDE TRANSPORT 7 256 0.0008603 0.005575
719 ENDOTHELIAL CELL DIFFERENTIATION 4 72 0.0008973 0.005804
720 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO HYPOXIA 3 32 0.0008982 0.005804
721 REGULATION OF SYSTEM PROCESS 10 507 0.0009055 0.005844
722 HOMEOSTATIC PROCESS 18 1337 0.0009233 0.00595
723 NEGATIVE REGULATION OF MAP KINASE ACTIVITY 4 73 0.000945 0.006065
724 G1 DNA DAMAGE CHECKPOINT 4 73 0.000945 0.006065
725 REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 4 73 0.000945 0.006065
726 REGULATION OF HORMONE SECRETION 7 262 0.0009846 0.006302
727 EMBRYONIC EYE MORPHOGENESIS 3 33 0.0009837 0.006302
728 REGULATION OF DENDRITE MORPHOGENESIS 4 74 0.0009944 0.006347
729 CELLULAR RESPONSE TO CARBOHYDRATE STIMULUS 4 74 0.0009944 0.006347
730 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 6 191 0.0009964 0.006351
731 PROTEIN ACETYLATION 5 129 0.001049 0.006675
732 FOREBRAIN NEURON DEVELOPMENT 3 34 0.001074 0.006801
733 ORGAN FORMATION 3 34 0.001074 0.006801
734 NEGATIVE REGULATION OF MITOTIC NUCLEAR DIVISION 3 34 0.001074 0.006801
735 NEURAL TUBE PATTERNING 3 34 0.001074 0.006801
736 POSITIVE REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 6 196 0.001138 0.007196
737 DIENCEPHALON DEVELOPMENT 4 77 0.001154 0.007284
738 RESPONSE TO MINERALOCORTICOID 3 35 0.00117 0.007366
739 INNER EAR RECEPTOR CELL DEVELOPMENT 3 35 0.00117 0.007366
740 REGULATION OF RECEPTOR MEDIATED ENDOCYTOSIS 4 78 0.001211 0.007612
741 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 14 926 0.001215 0.007632
742 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 8 352 0.001226 0.007685
743 NEGATIVE REGULATION OF MUSCLE ORGAN DEVELOPMENT 3 36 0.001271 0.007937
744 NEGATIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 3 36 0.001271 0.007937
745 POSITIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 3 36 0.001271 0.007937
746 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 7 274 0.001275 0.007955
747 NEGATIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 5 136 0.001327 0.008266
748 CIRCADIAN RHYTHM 5 137 0.001371 0.008527
749 REGULATION OF RECEPTOR INTERNALIZATION 3 37 0.001377 0.008531
750 REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION 3 37 0.001377 0.008531
751 NEGATIVE REGULATION OF EPITHELIAL CELL DIFFERENTIATION 3 37 0.001377 0.008531
752 METANEPHROS DEVELOPMENT 4 81 0.001393 0.008606
753 POSITIVE REGULATION OF MYELOID CELL DIFFERENTIATION 4 81 0.001393 0.008606
754 CELL PART MORPHOGENESIS 11 633 0.001403 0.00866
755 NEGATIVE REGULATION OF AXON EXTENSION 3 38 0.001488 0.009149
756 SUBSTRATE ADHESION DEPENDENT CELL SPREADING 3 38 0.001488 0.009149
757 REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 3 38 0.001488 0.009149
758 ESTABLISHMENT OR MAINTENANCE OF CELL POLARITY 5 141 0.001557 0.009557
759 REGULATION OF CALCIUM ION TRANSPORT 6 209 0.00158 0.009673
760 REGULATION OF PEPTIDE SECRETION 6 209 0.00158 0.009673
761 POSITIVE REGULATION OF VIRAL TRANSCRIPTION 3 39 0.001606 0.009791
762 NEGATIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 3 39 0.001606 0.009791
763 REGULATION OF AXON GUIDANCE 3 39 0.001606 0.009791
NumGOOverlapSizeP ValueAdj. P Value
1 WNT PROTEIN BINDING 17 31 1.104e-30 1.025e-27
2 WNT ACTIVATED RECEPTOR ACTIVITY 15 22 2.737e-29 1.271e-26
3 BETA CATENIN BINDING 20 84 4.56e-27 1.331e-24
4 FRIZZLED BINDING 16 36 5.73e-27 1.331e-24
5 ENZYME BINDING 43 1737 9.791e-17 1.819e-14
6 PROTEIN SERINE THREONINE KINASE ACTIVITY 22 445 1.85e-14 2.865e-12
7 TRANSCRIPTION FACTOR BINDING 23 524 5.453e-14 7.237e-12
8 KINASE BINDING 23 606 1.122e-12 1.303e-10
9 PROTEIN KINASE ACTIVITY 23 640 3.431e-12 3.188e-10
10 G PROTEIN COUPLED RECEPTOR BINDING 16 259 3.224e-12 3.188e-10
11 SIGNAL TRANSDUCER ACTIVITY 36 1731 1.179e-11 9.953e-10
12 PROTEIN DOMAIN SPECIFIC BINDING 22 624 1.566e-11 1.212e-09
13 UBIQUITIN LIKE PROTEIN LIGASE BINDING 15 264 5.262e-11 3.761e-09
14 ARMADILLO REPEAT DOMAIN BINDING 6 13 6.48e-11 4.3e-09
15 RECEPTOR BINDING 32 1476 7.953e-11 4.926e-09
16 MOLECULAR FUNCTION REGULATOR 30 1353 2.111e-10 1.226e-08
17 RECEPTOR AGONIST ACTIVITY 6 16 2.98e-10 1.629e-08
18 SMAD BINDING 9 72 4.276e-10 2.207e-08
19 RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 10 104 6.182e-10 3.023e-08
20 KINASE ACTIVITY 23 842 7.963e-10 3.699e-08
21 PROTEIN PHOSPHATASE TYPE 2A REGULATOR ACTIVITY 6 21 1.971e-09 8.72e-08
22 REGULATORY REGION NUCLEIC ACID BINDING 22 818 2.615e-09 1.104e-07
23 I SMAD BINDING 5 11 3.077e-09 1.243e-07
24 RECEPTOR REGULATOR ACTIVITY 7 45 8.314e-09 3.218e-07
25 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 23 992 1.768e-08 6.569e-07
26 RECEPTOR ACTIVATOR ACTIVITY 6 32 3.121e-08 1.115e-06
27 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 18 629 3.411e-08 1.174e-06
28 CORE PROMOTER PROXIMAL REGION DNA BINDING 14 371 4.545e-08 1.508e-06
29 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 13 315 5.019e-08 1.608e-06
30 PROTEIN DIMERIZATION ACTIVITY 24 1149 5.978e-08 1.851e-06
31 R SMAD BINDING 5 23 2.116e-07 6.343e-06
32 RHO GTPASE BINDING 7 78 4.117e-07 1.195e-05
33 GAMMA CATENIN BINDING 4 12 5.684e-07 1.6e-05
34 PHOSPHATASE REGULATOR ACTIVITY 7 87 8.713e-07 2.381e-05
35 ACTIVATING TRANSCRIPTION FACTOR BINDING 6 57 1.107e-06 2.857e-05
36 PDZ DOMAIN BINDING 7 90 1.098e-06 2.857e-05
37 MAP KINASE ACTIVITY 4 14 1.139e-06 2.86e-05
38 CHROMATIN BINDING 13 435 1.969e-06 4.815e-05
39 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 22 1199 2.048e-06 4.879e-05
40 PROTEIN SERINE THREONINE PHOSPHATASE ACTIVITY 6 64 2.211e-06 4.931e-05
41 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 15 588 2.189e-06 4.931e-05
42 RNA POLYMERASE II ACTIVATING TRANSCRIPTION FACTOR BINDING 5 36 2.229e-06 4.931e-05
43 DOUBLE STRANDED DNA BINDING 17 764 2.798e-06 6.045e-05
44 SEQUENCE SPECIFIC DNA BINDING 20 1037 3.034e-06 6.406e-05
45 ENZYME REGULATOR ACTIVITY 19 959 3.759e-06 7.761e-05
46 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 11 328 4.26e-06 8.603e-05
47 IDENTICAL PROTEIN BINDING 21 1209 8.453e-06 0.0001603
48 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 9 226 8.443e-06 0.0001603
49 ADENYL NUCLEOTIDE BINDING 24 1514 8.203e-06 0.0001603
50 RECEPTOR SIGNALING PROTEIN ACTIVITY 8 172 8.861e-06 0.0001646
51 RIBONUCLEOTIDE BINDING 27 1860 1.012e-05 0.0001844
52 TRANSCRIPTION COACTIVATOR ACTIVITY 10 296 1.113e-05 0.0001988
53 CALMODULIN BINDING 8 179 1.186e-05 0.0002078
54 CALMODULIN DEPENDENT PROTEIN KINASE ACTIVITY 4 28 2.184e-05 0.0003758
55 PROTEIN HETERODIMERIZATION ACTIVITY 12 468 2.309e-05 0.0003901
56 PROTEIN HOMODIMERIZATION ACTIVITY 15 722 2.532e-05 0.00042
57 P53 BINDING 5 67 4.93e-05 0.0008035
58 MACROMOLECULAR COMPLEX BINDING 21 1399 7.305e-05 0.00117
59 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR BINDING 3 15 8.87e-05 0.001397
60 PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 7 178 9.526e-05 0.001475
61 RECEPTOR SIGNALING PROTEIN SERINE THREONINE KINASE ACTIVITY 5 92 0.0002231 0.003397
62 ENHANCER BINDING 5 93 0.0002346 0.003516
63 PHOSPHORIC ESTER HYDROLASE ACTIVITY 9 368 0.0003584 0.005285
64 MITOGEN ACTIVATED PROTEIN KINASE BINDING 3 24 0.0003794 0.005508
65 GTPASE BINDING 8 295 0.0003883 0.00555
66 HORMONE RECEPTOR BINDING 6 168 0.0005096 0.007066
67 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 6 168 0.0005096 0.007066
68 BHLH TRANSCRIPTION FACTOR BINDING 3 28 0.0006036 0.008246
69 NF KAPPAB BINDING 3 30 0.0007416 0.009984
NumGOOverlapSizeP ValueAdj. P Value
1 WNT SIGNALOSOME 10 11 4.136e-22 2.416e-19
2 BETA CATENIN DESTRUCTION COMPLEX 10 14 3.708e-20 1.083e-17
3 ENDOCYTIC VESICLE MEMBRANE 14 152 3.484e-13 6.781e-11
4 PHOSPHATASE COMPLEX 9 48 9.491e-12 1.386e-09
5 PROTEIN PHOSPHATASE TYPE 2A COMPLEX 7 20 1.606e-11 1.876e-09
6 ENDOCYTIC VESICLE 15 256 3.406e-11 3.315e-09
7 CATALYTIC COMPLEX 27 1038 6.115e-11 5.102e-09
8 NUCLEAR CHROMATIN 15 291 2.062e-10 1.506e-08
9 TRANSCRIPTION FACTOR COMPLEX 15 298 2.871e-10 1.863e-08
10 CHROMATIN 17 441 1.051e-09 6.139e-08
11 CHROMOSOME 23 880 1.858e-09 9.864e-08
12 LATERAL PLASMA MEMBRANE 7 50 1.786e-08 8.69e-07
13 VESICLE MEMBRANE 15 512 3.895e-07 1.75e-05
14 NUCLEAR CHROMOSOME 15 523 5.096e-07 1.984e-05
15 SYNAPSE 18 754 5.029e-07 1.984e-05
16 NUCLEAR TRANSCRIPTION FACTOR COMPLEX 8 127 9.208e-07 3.361e-05
17 INTRACELLULAR VESICLE 23 1259 1.241e-06 4.263e-05
18 SCF UBIQUITIN LIGASE COMPLEX 5 34 1.661e-06 5.389e-05
19 CYTOPLASMIC VESICLE PART 15 601 2.861e-06 8.792e-05
20 TRANSFERASE COMPLEX 16 703 4.244e-06 0.0001239
21 EXTRACELLULAR MATRIX 12 426 9.081e-06 0.0002455
22 PROTEINACEOUS EXTRACELLULAR MATRIX 11 356 9.249e-06 0.0002455
23 PROTEIN KINASE COMPLEX 6 90 1.619e-05 0.0004112
24 GOLGI LUMEN 6 94 2.077e-05 0.0005054
25 RNA POLYMERASE II TRANSCRIPTION FACTOR COMPLEX 6 101 3.126e-05 0.0007302
26 CYTOSKELETAL PART 22 1436 3.519e-05 0.0007904
27 CLATHRIN COATED ENDOCYTIC VESICLE 5 65 4.257e-05 0.0009087
28 CELL SURFACE 15 757 4.357e-05 0.0009087
29 MICROTUBULE CYTOSKELETON 18 1068 5.98e-05 0.001204
30 LAMELLIPODIUM 7 172 7.684e-05 0.001496
31 TRANSCRIPTIONAL REPRESSOR COMPLEX 5 74 7.955e-05 0.001499
32 EXCITATORY SYNAPSE 7 197 0.0001787 0.003261
33 CLATHRIN COATED ENDOCYTIC VESICLE MEMBRANE 4 48 0.0001894 0.003352
34 CYTOSKELETON 25 1967 2e-04 0.003435
35 SYNAPSE PART 12 610 0.0002831 0.004723
36 NUCLEOPLASM PART 13 708 0.0003052 0.004951
37 MICROTUBULE ORGANIZING CENTER 12 623 0.0003425 0.005406
38 CLATHRIN COATED VESICLE 6 157 0.0003556 0.005465
39 CYTOPLASMIC MICROTUBULE 4 57 0.000369 0.005525
40 NUCLEAR EUCHROMATIN 3 24 0.0003794 0.00554
41 COATED VESICLE 7 234 0.0005064 0.007214
42 TRANSFERASE COMPLEX TRANSFERRING PHOSPHORUS CONTAINING GROUPS 7 237 0.0005463 0.007596
43 EARLY ENDOSOME MEMBRANE 5 113 0.0005766 0.007832
44 CHROMOSOME CENTROMERIC REGION 6 174 0.0006131 0.008138
45 CENTROSOME 10 487 0.0006661 0.008645
46 EUCHROMATIN 3 31 0.0008175 0.009946
47 ACTIN FILAMENT 4 70 0.000807 0.009946
48 CYCLIN DEPENDENT PROTEIN KINASE HOLOENZYME COMPLEX 3 31 0.0008175 0.009946

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04310_Wnt_signaling_pathway 119 151 7.013e-283 1.262e-280
2 hsa04390_Hippo_signaling_pathway 46 154 5.365e-68 4.829e-66
3 hsa04916_Melanogenesis 41 101 6.277e-67 3.766e-65
4 hsa04114_Oocyte_meiosis 22 114 1.656e-27 7.451e-26
5 hsa04340_Hedgehog_signaling_pathway 17 56 3.614e-25 1.301e-23
6 hsa04520_Adherens_junction 17 73 6.005e-23 1.801e-21
7 hsa04720_Long.term_potentiation 16 70 1.648e-21 4.237e-20
8 hsa04010_MAPK_signaling_pathway 21 268 7.623e-18 1.715e-16
9 hsa04662_B_cell_receptor_signaling_pathway 14 75 1.313e-17 2.625e-16
10 hsa04912_GnRH_signaling_pathway 15 101 3.243e-17 5.837e-16
11 hsa04350_TGF.beta_signaling_pathway 14 85 8.469e-17 1.386e-15
12 hsa04370_VEGF_signaling_pathway 13 76 6.668e-16 1e-14
13 hsa04110_Cell_cycle 14 128 3.136e-14 4.342e-13
14 hsa04360_Axon_guidance 14 130 3.904e-14 5.019e-13
15 hsa04510_Focal_adhesion 16 200 5.96e-14 7.151e-13
16 hsa04012_ErbB_signaling_pathway 12 87 1.362e-13 1.532e-12
17 hsa04971_Gastric_acid_secretion 11 74 6.299e-13 6.669e-12
18 hsa04650_Natural_killer_cell_mediated_cytotoxicity 13 136 1.57e-12 1.57e-11
19 hsa04660_T_cell_receptor_signaling_pathway 12 108 1.929e-12 1.827e-11
20 hsa04020_Calcium_signaling_pathway 14 177 2.839e-12 2.555e-11
21 hsa04722_Neurotrophin_signaling_pathway 11 127 2.576e-10 2.208e-09
22 hsa04380_Osteoclast_differentiation 11 128 2.804e-10 2.294e-09
23 hsa04151_PI3K_AKT_signaling_pathway 15 351 2.721e-09 2.13e-08
24 hsa04710_Circadian_rhythm_._mammal 6 23 3.631e-09 2.724e-08
25 hsa04062_Chemokine_signaling_pathway 11 189 1.742e-08 1.254e-07
26 hsa04664_Fc_epsilon_RI_signaling_pathway 8 79 2.272e-08 1.573e-07
27 hsa04270_Vascular_smooth_muscle_contraction 9 116 3.079e-08 2.052e-07
28 hsa04730_Long.term_depression 7 70 1.943e-07 1.249e-06
29 hsa04330_Notch_signaling_pathway 6 47 3.438e-07 2.134e-06
30 hsa03015_mRNA_surveillance_pathway 7 83 6.314e-07 3.788e-06
31 hsa04210_Apoptosis 7 89 1.017e-06 5.723e-06
32 hsa04970_Salivary_secretion 7 89 1.017e-06 5.723e-06
33 hsa04540_Gap_junction 7 90 1.098e-06 5.988e-06
34 hsa04530_Tight_junction 8 133 1.307e-06 6.918e-06
35 hsa04014_Ras_signaling_pathway 10 236 1.496e-06 7.694e-06
36 hsa04670_Leukocyte_transendothelial_migration 7 117 6.385e-06 3.193e-05
37 hsa04914_Progesterone.mediated_oocyte_maturation 6 87 1.333e-05 6.483e-05
38 hsa04910_Insulin_signaling_pathway 7 138 1.882e-05 8.916e-05
39 hsa04620_Toll.like_receptor_signaling_pathway 6 102 3.305e-05 0.0001525
40 hsa04115_p53_signaling_pathway 5 69 5.683e-05 0.0002557
41 hsa04120_Ubiquitin_mediated_proteolysis 6 139 0.0001844 0.0008095
42 hsa04810_Regulation_of_actin_cytoskeleton 7 214 0.0002961 0.001269
43 hsa04630_Jak.STAT_signaling_pathway 6 155 0.000332 0.00139
44 hsa04972_Pancreatic_secretion 5 101 0.0003443 0.001409
45 hsa04621_NOD.like_receptor_signaling_pathway 4 59 0.0004212 0.001685
46 hsa04141_Protein_processing_in_endoplasmic_reticulum 6 168 0.0005096 0.001994
47 hsa04622_RIG.I.like_receptor_signaling_pathway 4 71 0.0008513 0.00326
48 hsa04070_Phosphatidylinositol_signaling_system 4 78 0.001211 0.004539
49 hsa04962_Vasopressin.regulated_water_reabsorption 3 44 0.002277 0.008365
50 hsa04666_Fc_gamma_R.mediated_phagocytosis 4 95 0.002501 0.009002
51 hsa04742_Taste_transduction 3 52 0.003671 0.01296
52 hsa04920_Adipocytokine_signaling_pathway 3 68 0.007771 0.0269
53 hsa04740_Olfactory_transduction 7 388 0.008584 0.02915
54 hsa04976_Bile_secretion 3 71 0.00875 0.02917
55 hsa04960_Aldosterone.regulated_sodium_reabsorption 2 42 0.02589 0.08473
56 hsa00562_Inositol_phosphate_metabolism 2 57 0.04531 0.1457
57 hsa03008_Ribosome_biogenesis_in_eukaryotes 2 81 0.084 0.2653
58 hsa04144_Endocytosis 2 203 0.3408 1

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1

RP11-166D19.1

hsa-miR-106b-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-301a-3p;hsa-miR-324-3p;hsa-miR-330-5p;hsa-miR-484;hsa-miR-589-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-92a-3p;hsa-miR-940 15 FZD4 Sponge network -0.244 0.28835 -0.346 0.01097 0.384
2 MAGI2-AS3 hsa-miR-106b-5p;hsa-miR-1266-5p;hsa-miR-15b-5p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-589-3p;hsa-miR-616-5p;hsa-miR-9-5p;hsa-miR-92a-3p;hsa-miR-93-5p 13 CCND1 Sponge network -1.801 0 -0.902 1.0E-5 0.359
3 TOB1-AS1 hsa-miR-142-5p;hsa-miR-146a-5p;hsa-miR-150-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-181c-5p;hsa-miR-218-5p;hsa-miR-2355-3p;hsa-miR-330-3p;hsa-miR-450b-5p 10 PRKCA Sponge network 0.811 0 0.663 0 0.308
4 CASC2 hsa-miR-148b-3p;hsa-miR-17-3p;hsa-miR-192-3p;hsa-miR-193a-3p;hsa-miR-194-3p;hsa-miR-194-5p;hsa-miR-21-5p;hsa-miR-362-5p;hsa-miR-548j-5p;hsa-miR-885-5p 10 NFAT5 Sponge network -0.596 0.00187 -0.326 0.00164 0.281
5

RP11-166D19.1

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1266-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-425-5p;hsa-miR-589-3p;hsa-miR-616-5p;hsa-miR-92a-3p;hsa-miR-942-5p 16 CCND1 Sponge network -0.244 0.28835 -0.902 1.0E-5 0.253

Quest ID: 3fbdb67f0b721703ae56cf9c19685c2f