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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-100-5p SMAD7 0.23 0.34446 -0 0.98392 miRNAWalker2 validate -0.11 0.04468
2 hsa-miR-106b-5p PRRG1 0.14 0.51414 0.14 0.03454 miRNAWalker2 validate; MirTarget; miRNATAP -0.07 0.02884
3 hsa-miR-107 DAPK1 0.33 0.15378 0.09 0.61779 miRNAWalker2 validate; miRTarBase -0.16 0.04008
4 hsa-miR-10a-5p CYP8B1 -0.27 0.17524 1.39 0.01301 miRNAWalker2 validate -0.7 0.01373
5 hsa-miR-10a-5p MAPK8 -0.27 0.17524 0.06 0.17218 miRNAWalker2 validate -0.05 0.0181
6 hsa-miR-10a-5p PYGL -0.27 0.17524 0.55 0.04912 miRNAWalker2 validate -0.28 0.04613
7 hsa-miR-10a-5p ZNF618 -0.27 0.17524 0.08 0.11003 miRNAWalker2 validate; mirMAP -0.07 0.00856
8 hsa-miR-10b-5p NRP2 0.02 0.84842 -0.1 0.43013 miRNAWalker2 validate; miRNATAP -0.34 0.00069
9 hsa-miR-122-5p AACS 0.56 0.1942 -0.15 0.35856 miRNAWalker2 validate; miRTarBase -0.11 0.00342
10 hsa-miR-122-5p ALDOA 0.56 0.1942 -0.22 0.25911 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.11 0.02076
11 hsa-miR-122-5p CD83 0.56 0.1942 -0.04 0.89012 miRNAWalker2 validate -0.13 0.02836
12 hsa-miR-122-5p CPA3 0.56 0.1942 -0.56 0.019 miRNAWalker2 validate -0.13 0.01612
13 hsa-miR-122-5p DSTYK 0.56 0.1942 -0.23 0.02966 miRNAWalker2 validate; miRTarBase -0.06 0.01802
14 hsa-miR-122-5p DZIP1L 0.56 0.1942 -0.19 0.16432 miRNAWalker2 validate -0.09 0.00265
15 hsa-miR-122-5p EGLN3 0.56 0.1942 -0.2 0.51644 miRNAWalker2 validate; miRTarBase -0.2 0.0047
16 hsa-miR-122-5p LMNB2 0.56 0.1942 -0.2 0.25708 miRNAWalker2 validate -0.11 0.00881
17 hsa-miR-122-5p MPV17 0.56 0.1942 -0.18 0.16125 miRNAWalker2 validate -0.06 0.04828
18 hsa-miR-122-5p PHPT1 0.56 0.1942 -0.04 0.80549 miRNAWalker2 validate -0.07 0.0396
19 hsa-miR-122-5p PSMD10 0.56 0.1942 -0.21 0.25615 miRNAWalker2 validate -0.1 0.02354
20 hsa-miR-122-5p RAB6B 0.56 0.1942 -0.13 0.28733 miRNAWalker2 validate; miRTarBase -0.1 0.00041
21 hsa-miR-122-5p TPD52L2 0.56 0.1942 -0.01 0.92778 miRNAWalker2 validate; miRTarBase -0.06 0.01096
22 hsa-miR-1226-3p DDT -0.06 0.23641 0.44 0.07272 miRNAWalker2 validate -1.14 0.03118
23 hsa-miR-1236-3p LDOC1L 0.03 0.54197 -0.55 0.037 miRNAWalker2 validate -1.07 0.03226
24 hsa-miR-124-3p AURKB 0.11 0.13453 -0.04 0.63356 miRNAWalker2 validate -0.29 0.02536
25 hsa-miR-124-3p CKS2 0.11 0.13453 -0.29 0.20016 miRNAWalker2 validate -0.96 0.00263
26 hsa-miR-124-3p EFNA1 0.11 0.13453 -0.12 0.63145 miRNAWalker2 validate -0.81 0.02575
27 hsa-miR-124-3p FAM83H 0.11 0.13453 -0.08 0.66576 miRNAWalker2 validate -0.62 0.02117
28 hsa-miR-124-3p IL18R1 0.11 0.13453 -0.04 0.64416 miRNAWalker2 validate -0.26 0.04561
29 hsa-miR-124-3p SDC4 0.11 0.13453 -0.12 0.52279 miRNAWalker2 validate; MirTarget; miRNATAP -0.8 0.00274
30 hsa-miR-125a-3p IP6K2 0.22 0.22546 0.18 0.25596 miRNAWalker2 validate -0.2 0.01892
31 hsa-miR-125a-5p CDKN1A -0.2 0.44397 0.06 0.775 miRNAWalker2 validate; miRTarBase -0.18 0.02762
32 hsa-miR-125a-5p CGNL1 -0.2 0.44397 0.89 0.00929 miRNAWalker2 validate; miRanda -0.28 0.0393
33 hsa-miR-125a-5p NDEL1 -0.2 0.44397 0.01 0.91143 miRNAWalker2 validate -0.07 0.04288
34 hsa-miR-125b-5p FUS 0.25 0.38797 -0.04 0.77376 miRNAWalker2 validate -0.09 0.04787
35 hsa-miR-125b-5p HMGA2 0.25 0.38797 -0.6 0.02419 miRNAWalker2 validate; miRTarBase -0.2 0.03693
36 hsa-miR-125b-5p LIN28B 0.25 0.38797 -0.01 0.92264 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.07 0.01184
37 hsa-miR-125b-5p PLXND1 0.25 0.38797 -0.16 0.08894 miRNAWalker2 validate -0.1 0.00284
38 hsa-miR-125b-5p PSAT1 0.25 0.38797 -0.05 0.89936 miRNAWalker2 validate -0.31 0.01538
39 hsa-miR-1301-3p HIGD1A -0.01 0.71722 0.24 0.34854 miRNAWalker2 validate -2.23 0.00692
40 hsa-miR-130a-3p BMPR2 -0.02 0.92297 0.05 0.64147 miRNAWalker2 validate; MirTarget; miRNATAP -0.11 0.0293
41 hsa-miR-130b-3p AKAP11 0.05 0.68208 -0.13 0.58853 miRNAWalker2 validate; miRNATAP -0.35 0.04984
42 hsa-miR-130b-3p OTUD4 0.05 0.68208 -0.08 0.45645 miRNAWalker2 validate; miRNATAP -0.18 0.0309
43 hsa-miR-130b-3p PTP4A1 0.05 0.68208 0.07 0.78319 miRNAWalker2 validate; miRNATAP -0.41 0.03394
44 hsa-miR-130b-5p FASN 0.05 0.19689 0.53 0.057 miRNAWalker2 validate -1.67 0.0352
45 hsa-miR-132-3p ETNK2 0.03 0.63073 0.34 0.09005 miRNAWalker2 validate -0.94 0.01377
46 hsa-miR-133a-3p BCAN 0.04 0.51945 0.09 0.05682 miRNAWalker2 validate -0.2 0.01057
47 hsa-miR-133a-3p EGFR 0.04 0.51945 -0.07 0.75424 miRNAWalker2 validate; miRTarBase; MirTarget -1.29 0.0009
48 hsa-miR-133a-3p HCN2 0.04 0.51945 0.14 0.51559 miRNAWalker2 validate; miRTarBase -0.71 0.04658
49 hsa-miR-141-3p PPARA -0.44 8.0E-5 0.18 0.1046 miRNAWalker2 validate; miRTarBase -0.21 0.03014
50 hsa-miR-142-3p ABCC9 0.04 0.72618 0.41 0.12279 miRNAWalker2 validate -0.65 0.01135
51 hsa-miR-142-3p ETNK2 0.04 0.72618 0.34 0.09005 miRNAWalker2 validate -0.47 0.015
52 hsa-miR-146a-5p EGFR 0.14 0.40939 -0.07 0.75424 miRNAWalker2 validate -0.48 0.00056
53 hsa-miR-148a-3p CCNI 0.17 0.27929 -0.07 0.63194 miRNAWalker2 validate -0.26 0.00264
54 hsa-miR-149-5p AATF -0.09 0.30273 -0.02 0.83277 miRNAWalker2 validate -0.24 0.04933
55 hsa-miR-149-5p DDT -0.09 0.30273 0.44 0.07272 miRNAWalker2 validate -0.81 0.00587
56 hsa-miR-149-5p ETS2 -0.09 0.30273 -0.02 0.92787 miRNAWalker2 validate -0.74 0.01714
57 hsa-miR-151a-3p CCNE1 0.04 0.16538 -0.1 0.60975 miRNAWalker2 validate -1.43 0.03246
58 hsa-miR-155-5p AGL 0.06 0.18374 0.51 0.11552 miRNAWalker2 validate -1.42 0.04025
59 hsa-miR-155-5p ANPEP 0.06 0.18374 0.19 0.49064 miRNAWalker2 validate -1.36 0.02062
60 hsa-miR-155-5p B4GALT1 0.06 0.18374 -0.12 0.46339 miRNAWalker2 validate; mirMAP -0.71 0.04268
61 hsa-miR-155-5p CPT1A 0.06 0.18374 0.14 0.44457 miRNAWalker2 validate -0.83 0.02801
62 hsa-miR-155-5p CRAT 0.06 0.18374 0.35 0.00789 miRNAWalker2 validate -0.67 0.01965
63 hsa-miR-155-5p CTAGE5 0.06 0.18374 0.18 0.39722 miRNAWalker2 validate -1.2 0.00793
64 hsa-miR-155-5p DMD 0.06 0.18374 0 0.87312 miRNAWalker2 validate -0.14 0.02014
65 hsa-miR-155-5p EGFR 0.06 0.18374 -0.07 0.75424 miRNAWalker2 validate; MirTarget -1.74 0.00045 22213426 Furthermore miR-155 knock-down in RInk-1 cells resulted in the inhibition of cell growth and colony formation consistent with down-regulation of EGFR MT1-MMP and K-Ras expression
66 hsa-miR-155-5p GABARAPL1 0.06 0.18374 0.12 0.67753 miRNAWalker2 validate -1.92 0.00119
67 hsa-miR-155-5p GNPNAT1 0.06 0.18374 -0.12 0.56006 miRNAWalker2 validate -1.29 0.00251
68 hsa-miR-155-5p GPT2 0.06 0.18374 0.59 0.14834 miRNAWalker2 validate -2.33 0.00781
69 hsa-miR-155-5p IL13RA1 0.06 0.18374 0.24 0.33165 miRNAWalker2 validate; miRTarBase -1.15 0.02879
70 hsa-miR-155-5p LNX2 0.06 0.18374 -0.1 0.59732 miRNAWalker2 validate -1.2 0.00344
71 hsa-miR-155-5p LONP2 0.06 0.18374 0.3 0.1493 miRNAWalker2 validate -0.89 0.04417
72 hsa-miR-155-5p MYD88 0.06 0.18374 0.35 0.00943 miRNAWalker2 validate -0.63 0.03325
73 hsa-miR-155-5p MYO1E 0.06 0.18374 -0.11 0.56076 miRNAWalker2 validate -0.99 0.01525
74 hsa-miR-155-5p NAMPT 0.06 0.18374 -0.24 0.45229 miRNAWalker2 validate; miRNATAP -1.45 0.03271
75 hsa-miR-155-5p PHGDH 0.06 0.18374 0.33 0.29662 miRNAWalker2 validate -1.84 0.00648 24938880 Aim of this project was to determine expression of miR-155 miR-19a miR-181b miR-24 relative to let-7a in sera of 63 patients with EBC and 21 healthy controls
76 hsa-miR-155-5p PPP2R2A 0.06 0.18374 -0.13 0.43859 miRNAWalker2 validate -0.74 0.03366
77 hsa-miR-155-5p PSAT1 0.06 0.18374 -0.05 0.89936 miRNAWalker2 validate -1.83 0.02019
78 hsa-miR-155-5p RETSAT 0.06 0.18374 0.2 0.27423 miRNAWalker2 validate -1.02 0.00927
79 hsa-miR-155-5p SLC27A2 0.06 0.18374 0.57 0.14759 miRNAWalker2 validate -2.29 0.00646
80 hsa-miR-155-5p TMBIM6 0.06 0.18374 0.18 0.28991 miRNAWalker2 validate -1.05 0.00395
81 hsa-miR-15a-5p HERC6 0.18 0.3674 0.04 0.83964 miRNAWalker2 validate -0.19 0.04047
82 hsa-miR-15b-5p CCND1 0.28 0.23748 -0.28 0.35282 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.27 0.03772
83 hsa-miR-15b-5p PLSCR4 0.28 0.23748 0.02 0.93743 miRNAWalker2 validate; MirTarget -0.28 0.01393
84 hsa-miR-15b-5p SMAD7 0.28 0.23748 -0 0.98392 miRNAWalker2 validate; MirTarget; miRNATAP -0.12 0.04409
85 hsa-miR-16-5p CD274 0.28 0.3893 -0.02 0.85592 miRNAWalker2 validate; MirTarget -0.06 0.04602
86 hsa-miR-16-5p HERC6 0.28 0.3893 0.04 0.83964 miRNAWalker2 validate -0.12 0.04806
87 hsa-miR-16-5p PLSCR4 0.28 0.3893 0.02 0.93743 miRNAWalker2 validate; MirTarget -0.18 0.02943
88 hsa-miR-16-5p PTGS1 0.28 0.3893 -0.09 0.70066 miRNAWalker2 validate -0.15 0.04
89 hsa-miR-16-5p SAV1 0.28 0.3893 0.05 0.50417 miRNAWalker2 validate -0.05 0.02719
90 hsa-miR-16-5p SMAD7 0.28 0.3893 -0 0.98392 miRNAWalker2 validate; MirTarget; miRNATAP -0.11 0.00962
91 hsa-miR-16-5p USP53 0.28 0.3893 0.02 0.89833 miRNAWalker2 validate; miRNATAP -0.11 0.04178
92 hsa-miR-17-5p CCND1 -0.07 0.79091 -0.28 0.35282 miRNAWalker2 validate; MirTarget; TargetScan; miRNATAP -0.22 0.04711 18695042 Mammary epithelial cell-targeted cyclin D1 expression induced miR-17-5p and miR-20a expression in vivo and cyclin D1 bound the miR-17/20 cluster promoter regulatory region
93 hsa-miR-17-5p GPR137B -0.07 0.79091 -0.37 0.14479 miRNAWalker2 validate; miRTarBase; TargetScan; miRNATAP -0.21 0.02912
94 hsa-miR-17-5p NAT8L -0.07 0.79091 -0 0.99449 miRNAWalker2 validate; mirMAP -0.14 0.00713
95 hsa-miR-181a-5p AKAP12 -0.11 0.64975 0.16 0.49994 miRNAWalker2 validate -0.23 0.0228
96 hsa-miR-181a-5p GADD45G -0.11 0.64975 0.54 0.17956 miRNAWalker2 validate -0.42 0.01643
97 hsa-miR-181a-5p NKX3-2 -0.11 0.64975 0.03 0.77376 miRNAWalker2 validate; miRNATAP -0.11 0.02381
98 hsa-miR-181a-5p TGFBR3 -0.11 0.64975 -0.01 0.97548 miRNAWalker2 validate; mirMAP; miRNATAP -0.21 0.00644
99 hsa-miR-181d-5p DHRS4 -0.01 0.83654 0.53 0.00982 miRNAWalker2 validate -1.12 0.00529
100 hsa-miR-183-5p FAM188A -0.05 0.42998 -0.12 0.39256 miRNAWalker2 validate -0.45 0.02503
101 hsa-miR-183-5p INSIG1 -0.05 0.42998 0.68 0.12159 miRNAWalker2 validate -1.33 0.04205
102 hsa-miR-183-5p ZFHX4 -0.05 0.42998 0.4 0.0213 miRNAWalker2 validate -0.55 0.03655
103 hsa-miR-185-5p EPAS1 0.1 0.46192 0.02 0.92425 miRNAWalker2 validate; miRTarBase; MirTarget -0.43 0.00371
104 hsa-miR-186-5p TMBIM6 0.12 0.14218 0.18 0.28991 miRNAWalker2 validate -0.45 0.03688
105 hsa-miR-186-5p WLS 0.12 0.14218 0.23 0.41764 miRNAWalker2 validate -0.69 0.04766
106 hsa-miR-187-3p TUBG1 0.02 0.70394 0.1 0.41207 miRNAWalker2 validate -0.57 0.03603
107 hsa-miR-1914-3p PTCD1 0.09 0.35632 0.19 0.21488 miRNAWalker2 validate -0.36 0.02266
108 hsa-miR-192-5p ARL4C 0.45 0.16782 -0.45 0.10109 miRNAWalker2 validate -0.19 0.01876
109 hsa-miR-192-5p B3GALNT1 0.45 0.16782 -0.32 0.00364 miRNAWalker2 validate -0.11 0.0013
110 hsa-miR-192-5p CA8 0.45 0.16782 -0.46 8.0E-5 miRNAWalker2 validate -0.08 0.02364
111 hsa-miR-192-5p CD83 0.45 0.16782 -0.04 0.89012 miRNAWalker2 validate -0.16 0.04747
112 hsa-miR-192-5p CKLF 0.45 0.16782 -0.27 0.09823 miRNAWalker2 validate -0.1 0.0403
113 hsa-miR-192-5p CLIC1 0.45 0.16782 -0.39 0.0253 miRNAWalker2 validate -0.16 0.00175
114 hsa-miR-192-5p ELOVL1 0.45 0.16782 -0.14 0.20144 miRNAWalker2 validate -0.1 0.00187
115 hsa-miR-192-5p ENC1 0.45 0.16782 0.03 0.89957 miRNAWalker2 validate -0.17 0.02518
116 hsa-miR-192-5p FAIM 0.45 0.16782 -0.51 0.01338 miRNAWalker2 validate -0.13 0.04925
117 hsa-miR-192-5p FAM171B 0.45 0.16782 -0.38 0.02071 miRNAWalker2 validate -0.14 0.00707
118 hsa-miR-192-5p FHDC1 0.45 0.16782 -0.22 0.03374 miRNAWalker2 validate; MirTarget -0.11 0.00028
119 hsa-miR-192-5p FZD7 0.45 0.16782 -0.23 0.30795 miRNAWalker2 validate -0.23 0.00077
120 hsa-miR-192-5p GPC4 0.45 0.16782 -0.29 0.16621 miRNAWalker2 validate -0.2 0.00121
121 hsa-miR-192-5p GSG2 0.45 0.16782 -0.13 0.03853 miRNAWalker2 validate -0.05 0.00932
122 hsa-miR-192-5p ID4 0.45 0.16782 -0.41 0.26313 miRNAWalker2 validate -0.38 0.00042
123 hsa-miR-192-5p KCTD12 0.45 0.16782 -0.23 0.26808 miRNAWalker2 validate -0.15 0.02149
124 hsa-miR-192-5p LIMCH1 0.45 0.16782 -0.11 0.422 miRNAWalker2 validate -0.09 0.02158
125 hsa-miR-192-5p LMNB2 0.45 0.16782 -0.2 0.25708 miRNAWalker2 validate -0.14 0.00895
126 hsa-miR-192-5p LRP8 0.45 0.16782 -0.33 0.13394 miRNAWalker2 validate -0.24 0.00019
127 hsa-miR-192-5p MCM3 0.45 0.16782 -0.24 0.2025 miRNAWalker2 validate -0.12 0.0373
128 hsa-miR-192-5p MED22 0.45 0.16782 -0.15 0.33307 miRNAWalker2 validate; mirMAP -0.15 0.00117
129 hsa-miR-192-5p MYB 0.45 0.16782 -0.31 0.10306 miRNAWalker2 validate -0.18 0.00142
130 hsa-miR-192-5p PLAU 0.45 0.16782 -0.07 0.82417 miRNAWalker2 validate -0.26 0.0047
131 hsa-miR-192-5p PODXL 0.45 0.16782 -0.05 0.87612 miRNAWalker2 validate -0.2 0.0299
132 hsa-miR-192-5p PRICKLE1 0.45 0.16782 -0.05 0.80973 miRNAWalker2 validate -0.17 0.00325
133 hsa-miR-192-5p RASSF8 0.45 0.16782 -0.06 0.59041 miRNAWalker2 validate -0.07 0.02772
134 hsa-miR-192-5p RCC2 0.45 0.16782 -0.37 0.05119 miRNAWalker2 validate -0.21 0.00032
135 hsa-miR-192-5p SNRPD1 0.45 0.16782 -0.4 0.00671 miRNAWalker2 validate -0.1 0.03412
136 hsa-miR-192-5p SPARC 0.45 0.16782 -0.24 0.42268 miRNAWalker2 validate -0.18 0.04775
137 hsa-miR-192-5p STIL 0.45 0.16782 -0.24 0.01568 miRNAWalker2 validate -0.07 0.02535
138 hsa-miR-192-5p TBC1D22B 0.45 0.16782 -0.03 0.69509 miRNAWalker2 validate -0.06 0.03101
139 hsa-miR-192-5p TNFSF13 0.45 0.16782 -0.11 0.48782 miRNAWalker2 validate -0.16 0.00123
140 hsa-miR-192-5p TTF2 0.45 0.16782 -0.12 0.20487 miRNAWalker2 validate -0.08 0.00614
141 hsa-miR-192-5p ZNF519 0.45 0.16782 -0.24 0.0018 miRNAWalker2 validate -0.08 0.00047
142 hsa-miR-193b-3p APOBEC3B 0.02 0.92751 0.09 0.52251 miRNAWalker2 validate -0.14 0.03945
143 hsa-miR-193b-3p ATP13A2 0.02 0.92751 -0.03 0.64481 miRNAWalker2 validate -0.06 0.02788
144 hsa-miR-193b-3p CDK4 0.02 0.92751 -0.12 0.45614 miRNAWalker2 validate -0.19 0.0174
145 hsa-miR-193b-3p DOK2 0.02 0.92751 0.05 0.65109 miRNAWalker2 validate -0.12 0.03329
146 hsa-miR-193b-3p HM13 0.02 0.92751 -0 0.98157 miRNAWalker2 validate -0.16 0.0119
147 hsa-miR-193b-3p IRAK1 0.02 0.92751 -0.15 0.29128 miRNAWalker2 validate -0.15 0.04031
148 hsa-miR-193b-3p NLRP3 0.02 0.92751 0.03 0.89168 miRNAWalker2 validate -0.26 0.01848
149 hsa-miR-193b-3p SNRPB 0.02 0.92751 -0.08 0.62898 miRNAWalker2 validate -0.17 0.04746
150 hsa-miR-194-5p PTPN13 0.47 0.15528 -0.51 0.07673 miRNAWalker2 validate; miRTarBase -0.27 0.00152

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 ORGANIC ACID METABOLIC PROCESS 224 953 2.859e-31 1.33e-27
2 SMALL MOLECULE METABOLIC PROCESS 345 1767 7.482e-31 1.741e-27
3 MONOCARBOXYLIC ACID METABOLIC PROCESS 138 503 2.996e-26 4.647e-23
4 CARBOXYLIC ACID CATABOLIC PROCESS 74 205 3.656e-22 3.402e-19
5 ORGANIC ACID CATABOLIC PROCESS 74 205 3.656e-22 3.402e-19
6 RESPONSE TO ENDOGENOUS STIMULUS 272 1450 1.676e-21 1.299e-18
7 RESPONSE TO OXYGEN CONTAINING COMPOUND 260 1381 8.902e-21 5.917e-18
8 SMALL MOLECULE CATABOLIC PROCESS 94 328 1.231e-19 7.158e-17
9 RESPONSE TO ORGANIC CYCLIC COMPOUND 188 917 4.097e-19 2.118e-16
10 SINGLE ORGANISM CATABOLIC PROCESS 193 957 8.655e-19 4.027e-16
11 RESPONSE TO EXTERNAL STIMULUS 313 1821 1.186e-18 5.018e-16
12 SMALL MOLECULE BIOSYNTHETIC PROCESS 112 443 1.601e-18 6.21e-16
13 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 313 1848 1.075e-17 3.846e-15
14 RESPONSE TO LIPID 179 888 1.849e-17 6.146e-15
15 LIPID METABOLIC PROCESS 217 1158 3.674e-17 1.14e-14
16 RESPONSE TO HORMONE 178 893 7.289e-17 2.12e-14
17 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 163 799 1.781e-16 4.876e-14
18 CARDIOVASCULAR SYSTEM DEVELOPMENT 160 788 5.358e-16 1.312e-13
19 CIRCULATORY SYSTEM DEVELOPMENT 160 788 5.358e-16 1.312e-13
20 CARBOXYLIC ACID BIOSYNTHETIC PROCESS 76 270 1.167e-15 2.586e-13
21 ORGANIC ACID BIOSYNTHETIC PROCESS 76 270 1.167e-15 2.586e-13
22 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 190 1008 2.246e-15 4.75e-13
23 VASCULATURE DEVELOPMENT 109 469 2.796e-15 5.655e-13
24 ORGANIC HYDROXY COMPOUND METABOLIC PROCESS 111 482 3.046e-15 5.905e-13
25 RESPONSE TO NITROGEN COMPOUND 167 859 7.492e-15 1.394e-12
26 OXIDATION REDUCTION PROCESS 171 898 2.451e-14 4.36e-12
27 FATTY ACID METABOLIC PROCESS 78 296 2.53e-14 4.36e-12
28 ORGANONITROGEN COMPOUND CATABOLIC PROCESS 86 343 2.701e-14 4.488e-12
29 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 275 1672 5.845e-14 9.378e-12
30 CELLULAR AMINO ACID CATABOLIC PROCESS 42 112 7.641e-14 1.185e-11
31 CELLULAR LIPID METABOLIC PROCESS 171 913 1.122e-13 1.685e-11
32 REGULATION OF CELL DIFFERENTIATION 250 1492 1.205e-13 1.752e-11
33 CHEMICAL HOMEOSTASIS 165 874 1.552e-13 2.189e-11
34 RESPONSE TO EXTRACELLULAR STIMULUS 100 441 2.047e-13 2.802e-11
35 CELLULAR RESPONSE TO HORMONE STIMULUS 117 552 2.616e-13 3.478e-11
36 EMBRYO DEVELOPMENT 166 894 5.616e-13 7.259e-11
37 BLOOD VESSEL MORPHOGENESIS 86 364 9.562e-13 1.202e-10
38 CELL DEVELOPMENT 237 1426 1.369e-12 1.676e-10
39 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 109 513 1.482e-12 1.768e-10
40 REGULATION OF TRANSPORT 286 1804 1.55e-12 1.803e-10
41 CELLULAR RESPONSE TO LIPID 100 457 2.023e-12 2.296e-10
42 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 232 1395 2.274e-12 2.519e-10
43 REGULATION OF PHOSPHORUS METABOLIC PROCESS 261 1618 2.573e-12 2.784e-10
44 MONOCARBOXYLIC ACID CATABOLIC PROCESS 36 96 4.542e-12 4.804e-10
45 STEROID METABOLIC PROCESS 63 237 5.14e-12 5.314e-10
46 CELLULAR RESPONSE TO NITROGEN COMPOUND 106 505 6.643e-12 6.719e-10
47 TISSUE DEVELOPMENT 246 1518 7.399e-12 7.325e-10
48 SINGLE ORGANISM BIOSYNTHETIC PROCESS 222 1340 1.049e-11 1.017e-09
49 RESPONSE TO STEROID HORMONE 104 497 1.277e-11 1.213e-09
50 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 99 465 1.413e-11 1.315e-09
51 RESPONSE TO PEPTIDE 89 404 2.295e-11 2.094e-09
52 ORGAN MORPHOGENESIS 153 841 2.408e-11 2.155e-09
53 RESPONSE TO DRUG 93 431 2.733e-11 2.4e-09
54 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 302 1977 2.945e-11 2.537e-09
55 LOCOMOTION 190 1114 3.067e-11 2.595e-09
56 REGULATION OF CELLULAR COMPONENT MOVEMENT 142 771 5.311e-11 4.413e-09
57 RESPONSE TO ALCOHOL 81 362 8.11e-11 6.62e-09
58 BIOLOGICAL ADHESION 177 1032 9.672e-11 7.759e-09
59 NEURON PROJECTION MORPHOGENESIS 87 402 1.019e-10 8.035e-09
60 REGULATION OF CELL PROLIFERATION 238 1496 1.081e-10 8.381e-09
61 INTRACELLULAR SIGNAL TRANSDUCTION 247 1572 1.604e-10 1.223e-08
62 REGULATION OF KINASE ACTIVITY 140 776 3.179e-10 2.386e-08
63 TUBE DEVELOPMENT 108 552 3.444e-10 2.543e-08
64 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 235 1492 3.765e-10 2.737e-08
65 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 175 1036 4.248e-10 2.995e-08
66 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 175 1036 4.248e-10 2.995e-08
67 NEURON DEVELOPMENT 127 687 4.489e-10 3.118e-08
68 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 80 368 4.6e-10 3.148e-08
69 CENTRAL NERVOUS SYSTEM DEVELOPMENT 152 872 6.905e-10 4.656e-08
70 TAXIS 94 464 7.539e-10 5.011e-08
71 COENZYME METABOLIC PROCESS 63 265 7.976e-10 5.227e-08
72 LONG CHAIN FATTY ACID METABOLIC PROCESS 31 88 8.434e-10 5.451e-08
73 HEART DEVELOPMENT 94 466 9.526e-10 5.99e-08
74 RESPONSE TO ABIOTIC STIMULUS 172 1024 9.399e-10 5.99e-08
75 CELLULAR COMPONENT MORPHOGENESIS 155 900 1.124e-09 6.974e-08
76 GLAND DEVELOPMENT 83 395 1.232e-09 7.543e-08
77 CELLULAR RESPONSE TO PEPTIDE 64 274 1.26e-09 7.616e-08
78 CATABOLIC PROCESS 268 1773 1.349e-09 8.046e-08
79 ALPHA AMINO ACID CATABOLIC PROCESS 32 95 1.656e-09 9.752e-08
80 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 162 957 1.684e-09 9.797e-08
81 COFACTOR METABOLIC PROCESS 73 334 2.065e-09 1.186e-07
82 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 170 1021 2.304e-09 1.307e-07
83 ALCOHOL METABOLIC PROCESS 75 348 2.403e-09 1.347e-07
84 HOMEOSTATIC PROCESS 211 1337 2.78e-09 1.54e-07
85 NEURON PROJECTION DEVELOPMENT 104 545 3.047e-09 1.668e-07
86 REGULATION OF CELLULAR LOCALIZATION 203 1277 3.14e-09 1.699e-07
87 REGULATION OF CELL DEATH 228 1472 3.239e-09 1.732e-07
88 HEAD DEVELOPMENT 127 709 3.414e-09 1.805e-07
89 CELLULAR AMINO ACID METABOLIC PROCESS 72 332 3.778e-09 1.975e-07
90 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 185 1142 3.888e-09 2.01e-07
91 ION HOMEOSTASIS 108 576 4.16e-09 2.127e-07
92 REGULATION OF LIPID METABOLIC PROCESS 64 282 4.272e-09 2.16e-07
93 NEURON DIFFERENTIATION 149 874 4.835e-09 2.419e-07
94 ION TRANSPORT 200 1262 5.332e-09 2.64e-07
95 POSITIVE REGULATION OF MOLECULAR FUNCTION 267 1791 5.657e-09 2.771e-07
96 REGULATION OF CELL ADHESION 115 629 5.844e-09 2.833e-07
97 ARTERY DEVELOPMENT 27 75 5.945e-09 2.852e-07
98 ALPHA AMINO ACID METABOLIC PROCESS 55 229 6.342e-09 3.011e-07
99 EMBRYONIC MORPHOGENESIS 102 539 6.83e-09 3.21e-07
100 ORGANONITROGEN COMPOUND METABOLIC PROCESS 267 1796 7.396e-09 3.442e-07
101 ANGIOGENESIS 65 293 8.43e-09 3.884e-07
102 RESPONSE TO ACID CHEMICAL 69 319 8.894e-09 4.057e-07
103 MONOCARBOXYLIC ACID BIOSYNTHETIC PROCESS 45 172 9.319e-09 4.21e-07
104 MUSCLE STRUCTURE DEVELOPMENT 86 432 9.432e-09 4.22e-07
105 DEVELOPMENTAL GROWTH 71 333 1.022e-08 4.528e-07
106 LIPID LOCALIZATION 60 264 1.221e-08 5.359e-07
107 RESPIRATORY SYSTEM DEVELOPMENT 49 197 1.256e-08 5.463e-07
108 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 122 689 1.397e-08 6.02e-07
109 RESPONSE TO FATTY ACID 28 83 1.642e-08 7.008e-07
110 GROWTH 82 410 1.673e-08 7.079e-07
111 ORGANIC ACID TRANSPORT 59 261 1.982e-08 8.276e-07
112 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 161 983 1.992e-08 8.276e-07
113 BILE ACID METABOLIC PROCESS 17 35 2.088e-08 8.596e-07
114 REGULATION OF TRANSFERASE ACTIVITY 156 946 2.11e-08 8.61e-07
115 REGULATION OF PROTEIN MODIFICATION PROCESS 253 1710 2.987e-08 1.209e-06
116 POSITIVE REGULATION OF TRANSPORT 154 936 3.037e-08 1.218e-06
117 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 198 1275 3.173e-08 1.262e-06
118 RESPONSE TO NUTRIENT 47 191 3.535e-08 1.394e-06
119 REGULATION OF ANATOMICAL STRUCTURE SIZE 90 472 3.656e-08 1.429e-06
120 ANION TRANSPORT 95 507 3.703e-08 1.436e-06
121 TELENCEPHALON DEVELOPMENT 53 228 3.854e-08 1.482e-06
122 NEGATIVE REGULATION OF CELL DEATH 145 872 3.99e-08 1.522e-06
123 REGULATION OF RESPONSE TO WOUNDING 81 413 4.999e-08 1.891e-06
124 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 245 1656 5.107e-08 1.904e-06
125 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 179 1135 5.114e-08 1.904e-06
126 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 101 554 5.75e-08 2.107e-06
127 CARBOHYDRATE METABOLIC PROCESS 116 662 5.722e-08 2.107e-06
128 RESPONSE TO CORTICOSTEROID 44 176 5.823e-08 2.117e-06
129 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 93 498 6.069e-08 2.189e-06
130 CELLULAR CHEMICAL HOMEOSTASIS 103 570 6.733e-08 2.41e-06
131 REGULATION OF MEMBRANE POTENTIAL 70 343 8.123e-08 2.863e-06
132 CELLULAR RESPONSE TO ALCOHOL 33 115 8.069e-08 2.863e-06
133 BEHAVIOR 95 516 8.833e-08 3.09e-06
134 POSITIVE REGULATION OF CELL DIFFERENTIATION 137 823 8.951e-08 3.108e-06
135 CELLULAR RESPONSE TO FATTY ACID 20 51 1.064e-07 3.669e-06
136 POSITIVE REGULATION OF CATALYTIC ACTIVITY 226 1518 1.081e-07 3.699e-06
137 SULFUR COMPOUND METABOLIC PROCESS 72 359 1.1e-07 3.738e-06
138 TISSUE MORPHOGENESIS 97 533 1.147e-07 3.846e-06
139 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 206 1360 1.149e-07 3.846e-06
140 CELL MOTILITY 138 835 1.24e-07 4.008e-06
141 BILE ACID BIOSYNTHETIC PROCESS 12 20 1.234e-07 4.008e-06
142 LOCALIZATION OF CELL 138 835 1.24e-07 4.008e-06
143 ORGANIC ANION TRANSPORT 76 387 1.216e-07 4.008e-06
144 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 59 274 1.228e-07 4.008e-06
145 REGULATION OF NEURON PROJECTION DEVELOPMENT 79 408 1.278e-07 4.099e-06
146 NEUROGENESIS 211 1402 1.309e-07 4.172e-06
147 CELLULAR RESPONSE TO ACID CHEMICAL 43 175 1.39e-07 4.399e-06
148 RESPONSE TO KETONE 44 182 1.646e-07 5.175e-06
149 SINGLE ORGANISM BEHAVIOR 75 384 1.846e-07 5.764e-06
150 REGULATION OF MUSCLE SYSTEM PROCESS 46 195 1.888e-07 5.857e-06
151 REGULATION OF SECRETION 119 699 1.919e-07 5.914e-06
152 PHOSPHORYLATION 188 1228 2.029e-07 6.21e-06
153 EMBRYONIC ORGAN DEVELOPMENT 78 406 2.139e-07 6.504e-06
154 CIRCADIAN RHYTHM 36 137 2.435e-07 7.31e-06
155 VITAMIN METABOLIC PROCESS 33 120 2.432e-07 7.31e-06
156 CELLULAR AMINO ACID BIOSYNTHETIC PROCESS 28 93 2.54e-07 7.575e-06
157 REGULATION OF HORMONE LEVELS 88 478 2.63e-07 7.793e-06
158 EPITHELIUM DEVELOPMENT 151 945 2.675e-07 7.877e-06
159 CARDIAC SEPTUM MORPHOGENESIS 19 49 2.728e-07 7.984e-06
160 RESPONSE TO MECHANICAL STIMULUS 48 210 2.842e-07 8.266e-06
161 FATTY ACID CATABOLIC PROCESS 24 73 2.956e-07 8.543e-06
162 NEGATIVE REGULATION OF RESPONSE TO WOUNDING 39 156 3.229e-07 9.273e-06
163 MUSCLE TISSUE DEVELOPMENT 58 275 3.275e-07 9.35e-06
164 RESPONSE TO XENOBIOTIC STIMULUS 30 105 3.429e-07 9.611e-06
165 RESPONSE TO INSULIN 47 205 3.426e-07 9.611e-06
166 NEURON PROJECTION GUIDANCE 47 205 3.426e-07 9.611e-06
167 REGULATION OF GROWTH 109 633 3.537e-07 9.855e-06
168 AORTA DEVELOPMENT 17 41 3.71e-07 1.01e-05
169 REGULATION OF PROTEIN LOCALIZATION 151 950 3.701e-07 1.01e-05
170 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 49 218 3.672e-07 1.01e-05
171 MUSCLE CELL DIFFERENTIATION 52 237 3.649e-07 1.01e-05
172 MUSCLE CELL DEVELOPMENT 34 128 3.951e-07 1.069e-05
173 REGULATION OF GLUCOSE METABOLIC PROCESS 30 106 4.296e-07 1.156e-05
174 POSITIVE REGULATION OF LOCOMOTION 79 420 4.39e-07 1.174e-05
175 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 38 152 4.549e-07 1.21e-05
176 RESPONSE TO PURINE CONTAINING COMPOUND 39 158 4.598e-07 1.216e-05
177 CARDIAC SEPTUM DEVELOPMENT 26 85 4.784e-07 1.258e-05
178 RHYTHMIC PROCESS 61 298 4.873e-07 1.274e-05
179 PALLIUM DEVELOPMENT 38 153 5.434e-07 1.413e-05
180 RESPONSE TO INORGANIC SUBSTANCE 87 479 5.589e-07 1.445e-05
181 LIPID CATABOLIC PROCESS 53 247 5.922e-07 1.523e-05
182 REGULATION OF NEUROTRANSMITTER LEVELS 44 190 5.975e-07 1.528e-05
183 RESPONSE TO TRANSITION METAL NANOPARTICLE 37 148 6.411e-07 1.63e-05
184 SECOND MESSENGER MEDIATED SIGNALING 39 160 6.494e-07 1.633e-05
185 REGULATION OF CELL DEVELOPMENT 135 836 6.475e-07 1.633e-05
186 CELLULAR CATABOLIC PROCESS 197 1322 7.13e-07 1.784e-05
187 POSITIVE REGULATION OF KINASE ACTIVITY 87 482 7.342e-07 1.827e-05
188 FOREBRAIN DEVELOPMENT 69 357 8.412e-07 2.082e-05
189 CARDIAC CHAMBER DEVELOPMENT 36 144 9.035e-07 2.213e-05
190 REGULATION OF AXONOGENESIS 40 168 8.992e-07 2.213e-05
191 REGULATION OF HYDROLASE ACTIVITY 197 1327 9.276e-07 2.26e-05
192 TRANSMEMBRANE TRANSPORT 168 1098 9.699e-07 2.35e-05
193 REGULATION OF SYSTEM PROCESS 90 507 9.953e-07 2.4e-05
194 REGULATION OF CELL PROJECTION ORGANIZATION 97 558 1.009e-06 2.408e-05
195 WATER SOLUBLE VITAMIN METABOLIC PROCESS 26 88 1.008e-06 2.408e-05
196 NEGATIVE REGULATION OF WOUND HEALING 20 58 1.21e-06 2.871e-05
197 EAR DEVELOPMENT 44 195 1.27e-06 3e-05
198 CELLULAR RESPONSE TO INSULIN STIMULUS 36 146 1.287e-06 3.024e-05
199 MONOSACCHARIDE METABOLIC PROCESS 45 202 1.404e-06 3.282e-05
200 CATION TRANSPORT 128 796 1.586e-06 3.69e-05
201 CELLULAR HOMEOSTASIS 112 676 1.714e-06 3.967e-05
202 RESPONSE TO STARVATION 37 154 1.805e-06 4.157e-05
203 ADIPOSE TISSUE DEVELOPMENT 14 32 1.837e-06 4.211e-05
204 GLUCOSE METABOLIC PROCESS 31 119 1.987e-06 4.532e-05
205 LIPID OXIDATION 22 70 2.156e-06 4.895e-05
206 RESPONSE TO ESTROGEN 47 218 2.19e-06 4.947e-05
207 HEART MORPHOGENESIS 46 212 2.326e-06 5.207e-05
208 LIPID BIOSYNTHETIC PROCESS 93 539 2.328e-06 5.207e-05
209 REGULATION OF EPITHELIAL CELL PROLIFERATION 57 285 2.459e-06 5.474e-05
210 REGULATION OF WOUND HEALING 32 126 2.483e-06 5.502e-05
211 RESPONSE TO METAL ION 64 333 2.526e-06 5.569e-05
212 ORGANIC HYDROXY COMPOUND BIOSYNTHETIC PROCESS 40 175 2.7e-06 5.925e-05
213 CELLULAR LIPID CATABOLIC PROCESS 36 151 2.997e-06 6.548e-05
214 CARDIAC CHAMBER MORPHOGENESIS 28 104 3.053e-06 6.638e-05
215 ION TRANSMEMBRANE TRANSPORT 130 822 3.171e-06 6.862e-05
216 CELL SUBSTRATE ADHESION 38 164 3.361e-06 7.241e-05
217 CELL PART MORPHOGENESIS 105 633 3.41e-06 7.313e-05
218 HEPATICOBILIARY SYSTEM DEVELOPMENT 32 128 3.573e-06 7.59e-05
219 REGULATION OF COAGULATION 25 88 3.563e-06 7.59e-05
220 METAL ION TRANSPORT 98 582 3.742e-06 7.878e-05
221 MORPHOGENESIS OF AN EPITHELIUM 73 400 3.733e-06 7.878e-05
222 POSITIVE REGULATION OF RESPONSE TO STIMULUS 267 1929 3.811e-06 7.949e-05
223 REGULATION OF DEVELOPMENTAL GROWTH 57 289 3.86e-06 7.949e-05
224 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 252 1805 3.861e-06 7.949e-05
225 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 143 926 3.859e-06 7.949e-05
226 AMINO ACID BETAINE METABOLIC PROCESS 10 18 3.813e-06 7.949e-05
227 REGULATION OF PEPTIDE TRANSPORT 52 256 4.184e-06 8.576e-05
228 REGULATION OF CARBOHYDRATE METABOLIC PROCESS 39 172 4.397e-06 8.974e-05
229 PROTEIN PHOSPHORYLATION 145 944 4.433e-06 9.007e-05
230 EXTRACELLULAR STRUCTURE ORGANIZATION 59 304 4.47e-06 9.043e-05
231 TRANSITION METAL ION HOMEOSTASIS 28 106 4.57e-06 9.205e-05
232 REGULATION OF MAPK CASCADE 108 660 4.674e-06 9.375e-05
233 DICARBOXYLIC ACID METABOLIC PROCESS 27 101 5.267e-06 0.0001052
234 UROGENITAL SYSTEM DEVELOPMENT 58 299 5.455e-06 0.0001085
235 SKELETAL SYSTEM DEVELOPMENT 80 455 5.682e-06 0.0001125
236 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 126 801 5.886e-06 0.0001161
237 NEUTRAL LIPID METABOLIC PROCESS 24 85 6.233e-06 0.0001224
238 CARDIAC CELL DEVELOPMENT 17 49 6.876e-06 0.0001344
239 POSITIVE REGULATION OF HYDROLASE ACTIVITY 139 905 7.029e-06 0.0001368
240 CARBOHYDRATE DERIVATIVE METABOLIC PROCESS 157 1047 7.106e-06 0.0001372
241 PLACENTA DEVELOPMENT 33 138 7.108e-06 0.0001372
242 REGULATION OF BLOOD CIRCULATION 57 295 7.405e-06 0.0001424
243 REGULATION OF NEURON DIFFERENTIATION 93 554 7.471e-06 0.0001425
244 NEGATIVE REGULATION OF PHOSPHORYLATION 75 422 7.446e-06 0.0001425
245 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 63 337 7.674e-06 0.0001451
246 REPRODUCTIVE SYSTEM DEVELOPMENT 73 408 7.704e-06 0.0001451
247 TUBE MORPHOGENESIS 61 323 7.651e-06 0.0001451
248 HEXOSE METABOLIC PROCESS 36 157 7.733e-06 0.0001451
249 REGULATION OF CELL CELL ADHESION 69 380 8.135e-06 0.000152
250 UNSATURATED FATTY ACID METABOLIC PROCESS 28 109 8.165e-06 0.000152
251 GLUCOSE HOMEOSTASIS 38 170 8.26e-06 0.0001525
252 CARBOHYDRATE HOMEOSTASIS 38 170 8.26e-06 0.0001525
253 CARBOHYDRATE BIOSYNTHETIC PROCESS 30 121 8.501e-06 0.0001563
254 COENZYME BIOSYNTHETIC PROCESS 31 127 8.533e-06 0.0001563
255 REGULATION OF GLUCOSE IMPORT 19 60 9.286e-06 0.0001688
256 CELL PROJECTION ORGANIZATION 138 902 9.286e-06 0.0001688
257 ARACHIDONIC ACID METABOLIC PROCESS 17 50 9.383e-06 0.0001699
258 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 27 104 9.525e-06 0.0001718
259 REGULATION OF LIPID BIOSYNTHETIC PROCESS 31 128 1.012e-05 0.0001811
260 POSITIVE REGULATION OF LIPID METABOLIC PROCESS 31 128 1.012e-05 0.0001811
261 CELL PROLIFERATION 108 672 1.059e-05 0.0001887
262 REGULATION OF CELL SIZE 38 172 1.1e-05 0.0001953
263 REGULATION OF CELL MORPHOGENESIS 92 552 1.12e-05 0.0001982
264 REGULATION OF CARDIAC MUSCLE CONTRACTION 20 66 1.145e-05 0.0002018
265 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 118 750 1.15e-05 0.000202
266 POSITIVE REGULATION OF CELL DEATH 99 605 1.155e-05 0.0002021
267 ADULT BEHAVIOR 32 135 1.18e-05 0.0002056
268 STEROL METABOLIC PROCESS 30 123 1.204e-05 0.0002091
269 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 246 1784 1.257e-05 0.0002175
270 STRIATED MUSCLE CELL DIFFERENTIATION 38 173 1.266e-05 0.0002176
271 ARTERY MORPHOGENESIS 17 51 1.268e-05 0.0002176
272 POSITIVE REGULATION OF CELL PROLIFERATION 126 814 1.299e-05 0.0002221
273 VENTRICULAR SEPTUM MORPHOGENESIS 12 28 1.309e-05 0.0002224
274 DIGESTIVE SYSTEM DEVELOPMENT 34 148 1.31e-05 0.0002224
275 AROMATIC AMINO ACID FAMILY CATABOLIC PROCESS 10 20 1.315e-05 0.0002225
276 RESPONSE TO CYTOKINE 113 714 1.347e-05 0.0002271
277 REGULATION OF FAT CELL DIFFERENTIATION 27 106 1.391e-05 0.0002327
278 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 150 1004 1.389e-05 0.0002327
279 POSITIVE REGULATION OF CELL COMMUNICATION 215 1532 1.509e-05 0.0002515
280 CELLULAR RESPONSE TO STRESS 219 1565 1.513e-05 0.0002515
281 NEGATIVE REGULATION OF MOLECULAR FUNCTION 159 1079 1.644e-05 0.0002723
282 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 168 1152 1.708e-05 0.0002819
283 REGULATION OF BODY FLUID LEVELS 85 506 1.773e-05 0.0002915
284 CELLULAR CARBOHYDRATE METABOLIC PROCESS 33 144 1.84e-05 0.0003015
285 IN UTERO EMBRYONIC DEVELOPMENT 58 311 1.864e-05 0.0003024
286 RESPONSE TO OXYGEN LEVELS 58 311 1.864e-05 0.0003024
287 VASCULAR PROCESS IN CIRCULATORY SYSTEM 36 163 1.865e-05 0.0003024
288 SYNAPSE ORGANIZATION 33 145 2.141e-05 0.0003433
289 CARDIAC MUSCLE CELL DIFFERENTIATION 21 74 2.138e-05 0.0003433
290 REGULATION OF STEROID METABOLIC PROCESS 21 74 2.138e-05 0.0003433
291 HORMONE METABOLIC PROCESS 36 164 2.147e-05 0.0003433
292 CELLULAR RESPONSE TO CORTICOSTEROID STIMULUS 18 58 2.163e-05 0.0003447
293 LIPID MODIFICATION 43 210 2.235e-05 0.0003549
294 NEGATIVE REGULATION OF COAGULATION 16 48 2.27e-05 0.0003593
295 POSITIVE REGULATION OF GENE EXPRESSION 238 1733 2.33e-05 0.0003676
296 REGULATION OF MUSCLE TISSUE DEVELOPMENT 26 103 2.363e-05 0.0003715
297 EMBRYONIC ORGAN MORPHOGENESIS 53 279 2.488e-05 0.0003898
298 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 23 86 2.544e-05 0.0003972
299 CARDIAC MUSCLE TISSUE DEVELOPMENT 32 140 2.586e-05 0.0004024
300 INNER EAR MORPHOGENESIS 24 92 2.681e-05 0.0004159
301 RESPONSE TO CAMP 26 104 2.833e-05 0.0004365
302 COFACTOR BIOSYNTHETIC PROCESS 36 166 2.83e-05 0.0004365
303 BIOTIN METABOLIC PROCESS 8 14 2.85e-05 0.0004377
304 REGULATION OF MUSCLE CONTRACTION 33 147 2.88e-05 0.0004408
305 VENTRICULAR SEPTUM DEVELOPMENT 17 54 2.958e-05 0.0004512
306 CIRCULATORY SYSTEM PROCESS 65 366 3.013e-05 0.0004581
307 REGULATION OF FATTY ACID METABOLIC PROCESS 23 87 3.111e-05 0.0004715
308 CEREBRAL CORTEX DEVELOPMENT 26 105 3.386e-05 0.0005116
309 CELLULAR RESPONSE TO CYTOKINE STIMULUS 97 606 3.46e-05 0.000521
310 SMOOTH MUSCLE TISSUE DEVELOPMENT 9 18 3.621e-05 0.0005383
311 REGULATION OF CERAMIDE BIOSYNTHETIC PROCESS 7 11 3.597e-05 0.0005383
312 CONNECTIVE TISSUE DEVELOPMENT 40 194 3.602e-05 0.0005383
313 NEGATIVE REGULATION OF CELL COMMUNICATION 171 1192 3.611e-05 0.0005383
314 POSITIVE REGULATION OF MUSCLE HYPERTROPHY 10 22 3.76e-05 0.0005519
315 POSITIVE REGULATION OF CARDIAC MUSCLE HYPERTROPHY 10 22 3.76e-05 0.0005519
316 REGULATION OF ION TRANSPORT 95 592 3.76e-05 0.0005519
317 PYRIDINE CONTAINING COMPOUND BIOSYNTHETIC PROCESS 10 22 3.76e-05 0.0005519
318 POSITIVE REGULATION OF CELL ADHESION 66 376 3.82e-05 0.0005589
319 AMINO ACID TRANSPORT 29 124 3.877e-05 0.0005638
320 MONOCARBOXYLIC ACID TRANSPORT 29 124 3.877e-05 0.0005638
321 EAR MORPHOGENESIS 27 112 4.018e-05 0.0005825
322 CELLULAR RESPONSE TO OXYGEN LEVELS 32 143 4.038e-05 0.0005834
323 MUSCLE ORGAN DEVELOPMENT 52 277 4.106e-05 0.0005905
324 CELLULAR TRANSITION METAL ION HOMEOSTASIS 21 77 4.112e-05 0.0005905
325 RESPONSE TO WOUNDING 91 563 4.14e-05 0.0005927
326 REGULATION OF PEPTIDE SECRETION 42 209 4.387e-05 0.0006262
327 CELLULAR RESPONSE TO EXTERNAL STIMULUS 50 264 4.513e-05 0.0006422
328 CELL MATRIX ADHESION 28 119 4.66e-05 0.0006598
329 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 32 144 4.665e-05 0.0006598
330 REGULATION OF EXTENT OF CELL GROWTH 25 101 4.789e-05 0.0006753
331 REGULATED EXOCYTOSIS 44 224 5.18e-05 0.0007259
332 NEGATIVE REGULATION OF CELL PROLIFERATION 101 643 5.173e-05 0.0007259
333 ISOPRENOID METABOLIC PROCESS 29 126 5.3e-05 0.0007405
334 REGULATION OF CELLULAR COMPONENT SIZE 60 337 5.556e-05 0.0007671
335 CELLULAR RESPONSE TO STEROL 8 15 5.532e-05 0.0007671
336 REGULATION OF INTRACELLULAR TRANSPORT 98 621 5.547e-05 0.0007671
337 AMINO ACID IMPORT 8 15 5.532e-05 0.0007671
338 STEROID BIOSYNTHETIC PROCESS 27 114 5.594e-05 0.0007701
339 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 43 218 5.663e-05 0.0007773
340 HIPPOCAMPUS DEVELOPMENT 20 73 5.795e-05 0.0007907
341 CELLULAR RESPONSE TO KETONE 20 73 5.795e-05 0.0007907
342 BRANCHED CHAIN AMINO ACID METABOLIC PROCESS 10 23 6.014e-05 0.0008182
343 SENSORY ORGAN DEVELOPMENT 81 493 6.098e-05 0.0008273
344 REGULATION OF PROTEIN SECRETION 67 389 6.117e-05 0.0008273
345 RESPONSE TO ESTRADIOL 32 146 6.193e-05 0.0008347
346 DRUG TRANSMEMBRANE TRANSPORT 9 19 6.225e-05 0.0008347
347 REGULATION OF STRIATED MUSCLE CONTRACTION 21 79 6.209e-05 0.0008347
348 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 97 616 6.571e-05 0.0008786
349 POSITIVE REGULATION OF CELL CYCLE 59 332 6.734e-05 0.0008978
350 PRIMARY ALCOHOL METABOLIC PROCESS 15 47 7.215e-05 0.0009592
351 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 87 541 7.282e-05 0.0009626
352 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 87 541 7.282e-05 0.0009626
353 REGULATION OF MUSCLE ADAPTATION 18 63 7.375e-05 0.0009721
354 ORGANOPHOSPHATE METABOLIC PROCESS 131 885 7.453e-05 0.0009796
355 ADULT LOCOMOTORY BEHAVIOR 21 80 7.578e-05 0.0009933
356 L AMINO ACID IMPORT 7 12 7.83e-05 0.001023
357 CELL GROWTH 30 135 7.935e-05 0.001034
358 CELLULAR GLUCAN METABOLIC PROCESS 17 58 8.164e-05 0.001058
359 GLUCAN METABOLIC PROCESS 17 58 8.164e-05 0.001058
360 MONOVALENT INORGANIC CATION HOMEOSTASIS 28 123 8.685e-05 0.001123
361 NEGATIVE REGULATION OF GROWTH 45 236 8.97e-05 0.001156
362 STEROID CATABOLIC PROCESS 10 24 9.321e-05 0.001198
363 REGULATION OF HOMEOSTATIC PROCESS 74 447 9.753e-05 0.00125
364 ACTIVATION OF PROTEIN KINASE ACTIVITY 51 279 9.835e-05 0.001257
365 POSITIVE REGULATION OF MAPK CASCADE 77 470 0.0001008 0.001281
366 WOUND HEALING 77 470 0.0001008 0.001281
367 INTRACELLULAR LIPID TRANSPORT 9 20 0.0001024 0.001299
368 PROTEIN HOMOTETRAMERIZATION 17 59 0.0001033 0.0013
369 SULFUR COMPOUND BIOSYNTHETIC PROCESS 40 203 0.0001034 0.0013
370 REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 17 59 0.0001033 0.0013
371 REGULATION OF INFLAMMATORY RESPONSE 53 294 0.0001055 0.001323
372 NEGATIVE REGULATION OF CELL DIFFERENTIATION 95 609 0.0001107 0.001384
373 TERPENOID METABOLIC PROCESS 25 106 0.0001116 0.001392
374 MONOSACCHARIDE BIOSYNTHETIC PROCESS 16 54 0.0001138 0.001405
375 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 24 100 0.0001135 0.001405
376 LIMBIC SYSTEM DEVELOPMENT 24 100 0.0001135 0.001405
377 SODIUM ION TRANSPORT 31 144 0.0001138 0.001405
378 NEGATIVE REGULATION OF AXONOGENESIS 18 65 0.0001151 0.001417
379 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 44 232 0.0001213 0.00149
380 REGULATION OF STEROID BIOSYNTHETIC PROCESS 15 49 0.000123 0.001506
381 NEGATIVE REGULATION OF CELL DEVELOPMENT 54 303 0.0001243 0.001518
382 RESPONSE TO FLUID SHEAR STRESS 12 34 0.0001278 0.001552
383 REGULATION OF CELL GROWTH 66 391 0.0001276 0.001552
384 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 17 60 0.0001299 0.001575
385 DEVELOPMENTAL CELL GROWTH 20 77 0.0001305 0.001577
386 THIOESTER METABOLIC PROCESS 21 83 0.0001343 0.001615
387 ACYL COA METABOLIC PROCESS 21 83 0.0001343 0.001615
388 EPITHELIAL CELL PROLIFERATION 22 89 0.000136 0.00163
389 RESPONSE TO ORGANOPHOSPHORUS 30 139 0.0001388 0.00166
390 DRUG TRANSPORT 10 25 0.0001405 0.001676
391 REGULATION OF ACTIN FILAMENT BASED PROCESS 55 312 0.0001451 0.001727
392 REGULATION OF HORMONE SECRETION 48 262 0.0001468 0.001742
393 GLYCEROLIPID METABOLIC PROCESS 61 356 0.000148 0.001753
394 ENERGY RESERVE METABOLIC PROCESS 19 72 0.0001519 0.001782
395 REGULATION OF SPHINGOLIPID BIOSYNTHETIC PROCESS 7 13 0.0001539 0.001782
396 REGULATION OF MEMBRANE LIPID METABOLIC PROCESS 7 13 0.0001539 0.001782
397 ORGANIC HYDROXY COMPOUND CATABOLIC PROCESS 19 72 0.0001519 0.001782
398 REGULATION OF CHOLESTEROL BIOSYNTHETIC PROCESS 7 13 0.0001539 0.001782
399 DICARBOXYLIC ACID BIOSYNTHETIC PROCESS 7 13 0.0001539 0.001782
400 CARNITINE METABOLIC PROCESS 7 13 0.0001539 0.001782
401 SEMAPHORIN PLEXIN SIGNALING PATHWAY INVOLVED IN NEURON PROJECTION GUIDANCE 7 13 0.0001539 0.001782
402 VENTRICULAR CARDIAC MUSCLE CELL DEVELOPMENT 7 13 0.0001539 0.001782
403 REGULATION OF COENZYME METABOLIC PROCESS 15 50 0.0001584 0.001816
404 CELLULAR RESPONSE TO CAMP 15 50 0.0001584 0.001816
405 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 128 876 0.0001584 0.001816
406 REGULATION OF COFACTOR METABOLIC PROCESS 15 50 0.0001584 0.001816
407 REGULATION OF CELLULAR KETONE METABOLIC PROCESS 35 173 0.0001591 0.001819
408 NEGATIVE REGULATION OF LOCOMOTION 48 263 0.0001612 0.001821
409 REGULATION OF SYSTEMIC ARTERIAL BLOOD PRESSURE 21 84 0.0001612 0.001821
410 CARDIOCYTE DIFFERENTIATION 23 96 0.0001606 0.001821
411 ICOSANOID METABOLIC PROCESS 23 96 0.0001606 0.001821
412 FATTY ACID DERIVATIVE METABOLIC PROCESS 23 96 0.0001606 0.001821
413 REGULATION OF HEART CONTRACTION 42 221 0.0001632 0.001838
414 REGULATION OF ORGAN MORPHOGENESIS 45 242 0.0001641 0.001844
415 MORPHOGENESIS OF A BRANCHING STRUCTURE 34 167 0.0001727 0.001937
416 RESPONSE TO IRON ION 12 35 0.0001756 0.001964
417 REGULATION OF ORGAN GROWTH 19 73 0.000185 0.002059
418 REGULATION OF MUSCLE ORGAN DEVELOPMENT 24 103 0.0001849 0.002059
419 CELL DEATH 143 1001 0.0001904 0.002114
420 FORMATION OF PRIMARY GERM LAYER 25 110 0.0002084 0.002308
421 ORGAN GROWTH 18 68 0.0002153 0.00238
422 CELLULAR HORMONE METABOLIC PROCESS 24 104 0.0002163 0.002385
423 CYCLIC NUCLEOTIDE MEDIATED SIGNALING 14 46 0.00022 0.00242
424 CIRCADIAN REGULATION OF GENE EXPRESSION 16 57 0.0002289 0.002512
425 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 110 740 0.0002342 0.002564
426 REGULATION OF NUCLEOTIDE METABOLIC PROCESS 40 211 0.0002433 0.002657
427 POSITIVE REGULATION OF SECRETION 62 370 0.0002468 0.002689
428 REGULATION OF CHOLESTEROL METABOLIC PROCESS 9 22 0.0002485 0.002702
429 HINDBRAIN DEVELOPMENT 29 137 0.0002525 0.002739
430 IRON ION HOMEOSTASIS 18 69 0.0002625 0.00284
431 NEGATIVE REGULATION OF DEFENSE RESPONSE 30 144 0.0002672 0.002884
432 EPOXYGENASE P450 PATHWAY 8 18 0.0002798 0.003014
433 REGULATION OF OSSIFICATION 35 178 0.0002827 0.003038
434 CARDIAC VENTRICLE DEVELOPMENT 24 106 0.0002936 0.003148
435 REGULATION OF FATTY ACID TRANSPORT 10 27 0.0002965 0.003172
436 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 40 213 0.000298 0.003173
437 CELLULAR MODIFIED AMINO ACID METABOLIC PROCESS 41 220 0.000298 0.003173
438 REGULATION OF HEART GROWTH 13 42 0.0003045 0.003235
439 REGULATION OF MUSCLE HYPERTROPHY 12 37 0.000318 0.003363
440 CAMP MEDIATED SIGNALING 12 37 0.000318 0.003363
441 AMINOGLYCAN BIOSYNTHETIC PROCESS 24 107 0.0003406 0.003594
442 POSITIVE REGULATION OF CELL CELL ADHESION 44 243 0.0003531 0.003717
443 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 14 48 0.0003601 0.003783
444 REGULATION OF LIPID TRANSPORT 22 95 0.0003694 0.003865
445 TRABECULA FORMATION 9 23 0.0003696 0.003865
446 GLUTAMINE FAMILY AMINO ACID METABOLIC PROCESS 17 65 0.0003728 0.003889
447 ANION TRANSMEMBRANE TRANSPORT 45 251 0.0003816 0.003972
448 CARBOHYDRATE DERIVATIVE CATABOLIC PROCESS 34 174 0.0003866 0.004007
449 REGULATION OF LIPASE ACTIVITY 20 83 0.0003866 0.004007
450 ALPHA AMINO ACID BIOSYNTHETIC PROCESS 19 77 0.0003885 0.004017
451 LOCOMOTORY BEHAVIOR 35 181 0.0003928 0.004052
452 ACUTE PHASE RESPONSE 13 43 0.0003941 0.004057
453 NEGATIVE REGULATION OF CELL ADHESION 41 223 0.0003988 0.004096
454 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 31 154 0.0004017 0.004117
455 CELL CELL SIGNALING 112 767 0.0004097 0.00418
456 REGULATION OF PROTEOLYSIS 105 711 0.0004089 0.00418
457 GLUTAMATE METABOLIC PROCESS 10 28 0.0004173 0.00423
458 AROMATIC AMINO ACID FAMILY METABOLIC PROCESS 10 28 0.0004173 0.00423
459 REGULATION OF FATTY ACID OXIDATION 10 28 0.0004173 0.00423
460 REGULATION OF GLUCONEOGENESIS 12 38 0.0004198 0.004247
461 RESPONSE TO CARBOHYDRATE 33 168 0.0004235 0.004275
462 REGULATION OF RESPONSE TO STRESS 197 1468 0.0004268 0.004298
463 NEURON RECOGNITION 11 33 0.0004305 0.004327
464 CALCIUM MEDIATED SIGNALING 21 90 0.0004462 0.004475
465 REGULATION OF GTPASE ACTIVITY 100 673 0.0004483 0.004486
466 NEUROTRANSMITTER TRANSPORT 31 155 0.0004515 0.0045
467 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 91 602 0.000452 0.0045
468 POSITIVE REGULATION OF LIPID BIOSYNTHETIC PROCESS 17 66 0.0004526 0.0045
469 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 151 1087 0.0004606 0.00457
470 CARBOHYDRATE DERIVATIVE BIOSYNTHETIC PROCESS 90 595 0.0004742 0.004695
471 POSITIVE REGULATION OF MEMBRANE PROTEIN ECTODOMAIN PROTEOLYSIS 7 15 0.0004754 0.004696
472 ORGANIC ACID TRANSMEMBRANE TRANSPORT 23 103 0.0004795 0.004727
473 REGULATION OF PROTEIN IMPORT 35 183 0.0004858 0.004779
474 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 27 129 0.0004892 0.004802
475 RESPONSE TO ETHANOL 28 136 0.0005139 0.005034
476 LIPID HOMEOSTASIS 24 110 0.0005237 0.005119
477 IMMUNE SYSTEM PROCESS 257 1984 0.0005279 0.005149
478 CELLULAR RESPONSE TO OXIDATIVE STRESS 35 184 0.0005392 0.005249
479 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 54 321 0.000544 0.005285
480 REGULATION OF AXON GUIDANCE 12 39 0.0005478 0.00531
481 ACUTE INFLAMMATORY RESPONSE 18 73 0.0005524 0.005344
482 POSITIVE REGULATION OF PROTEIN IMPORT 23 104 0.0005543 0.005351
483 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 25 117 0.0005634 0.005406
484 MAMMARY GLAND DEVELOPMENT 25 117 0.0005634 0.005406
485 RESPONSE TO TOXIC SUBSTANCE 43 241 0.0005631 0.005406
486 GENERATION OF PRECURSOR METABOLITES AND ENERGY 50 292 0.0005678 0.005436
487 REGULATION OF ORGANIC ACID TRANSPORT 14 50 0.0005704 0.005449
488 NEGATIVE REGULATION OF TRANSPORT 72 458 0.0005716 0.00545
489 MONOVALENT INORGANIC CATION TRANSPORT 69 435 0.0005733 0.005455
490 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 10 29 0.0005761 0.005471
491 INORGANIC ION TRANSMEMBRANE TRANSPORT 88 583 0.0005831 0.005526
492 RESPONSE TO OXIDATIVE STRESS 58 352 0.000592 0.005598
493 OUTFLOW TRACT MORPHOGENESIS 15 56 0.0006161 0.005815
494 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 79 514 0.0006356 0.005987
495 REGULATION OF SYSTEMIC ARTERIAL BLOOD PRESSURE MEDIATED BY A CHEMICAL SIGNAL 13 45 0.0006413 0.006028
496 POLYSACCHARIDE METABOLIC PROCESS 19 80 0.0006487 0.006086
497 REGULATION OF ICOSANOID SECRETION 8 20 0.0006618 0.006136
498 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 28 138 0.0006557 0.006136
499 REGULATION OF EXOCYTOSIS 35 186 0.000662 0.006136
500 REFLEX 8 20 0.0006618 0.006136
501 REGULATION OF ACUTE INFLAMMATORY RESPONSE 18 74 0.0006579 0.006136
502 RESPONSE TO LEPTIN 8 20 0.0006618 0.006136
503 REGULATION OF CELL ACTIVATION 75 484 0.000679 0.006281
504 POSITIVE REGULATION OF ION TRANSPORT 42 236 0.000684 0.006315
505 REGULATION OF MUSCLE CELL DIFFERENTIATION 30 152 0.0006955 0.006408
506 FATTY ACID BETA OXIDATION 14 51 0.0007096 0.006499
507 POSITIVE REGULATION OF LIPID TRANSPORT 14 51 0.0007096 0.006499
508 FATTY ACYL COA METABOLIC PROCESS 14 51 0.0007096 0.006499
509 COGNITION 44 251 0.0007172 0.006556
510 REGULATION OF EPITHELIAL CELL MIGRATION 32 166 0.0007198 0.006568
511 MOVEMENT IN ENVIRONMENT OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 20 87 0.0007393 0.006641
512 ENTRY INTO CELL OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 20 87 0.0007393 0.006641
513 VIRAL ENTRY INTO HOST CELL 20 87 0.0007393 0.006641
514 ENTRY INTO OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 20 87 0.0007393 0.006641
515 FAT CELL DIFFERENTIATION 23 106 0.0007346 0.006641
516 MOVEMENT IN HOST ENVIRONMENT 20 87 0.0007393 0.006641
517 ENTRY INTO HOST 20 87 0.0007393 0.006641
518 ENTRY INTO HOST CELL 20 87 0.0007393 0.006641
519 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 73 470 0.0007437 0.006668
520 GLYCOGEN BIOSYNTHETIC PROCESS 9 25 0.0007576 0.006749
521 POSITIVE REGULATION OF PROTEOLYSIS 59 363 0.0007563 0.006749
522 GLUCAN BIOSYNTHETIC PROCESS 9 25 0.0007576 0.006749
523 RESPONSE TO MONOAMINE 11 35 0.0007586 0.006749
524 SECRETION BY CELL 75 486 0.000765 0.00677
525 SECRETION 88 588 0.0007653 0.00677
526 CALCIUM ION REGULATED EXOCYTOSIS 19 81 0.0007637 0.00677
527 DICARBOXYLIC ACID CATABOLIC PROCESS 7 16 0.0007671 0.006773
528 SMOOTH MUSCLE CELL DIFFERENTIATION 10 30 0.0007819 0.006852
529 CELLULAR GLUCOSE HOMEOSTASIS 18 75 0.0007803 0.006852
530 REGULATION OF GLUCOSE TRANSPORT 22 100 0.0007796 0.006852
531 REGULATION OF DENDRITIC SPINE MORPHOGENESIS 10 30 0.0007819 0.006852
532 CELLULAR RESPONSE TO CHOLESTEROL 6 12 0.0007853 0.006852
533 POSITIVE REGULATION OF AXONOGENESIS 17 69 0.0007863 0.006852
534 POSITIVE REGULATION OF INSULIN LIKE GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 6 12 0.0007853 0.006852
535 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 49 289 0.0008021 0.006976
536 POSITIVE REGULATION OF PEPTIDASE ACTIVITY 30 154 0.0008692 0.007545
537 REGULATION OF LIPID CATABOLIC PROCESS 14 52 0.0008765 0.007595
538 REGULATION OF CYTOPLASMIC TRANSPORT 74 481 0.0009017 0.007798
539 LUNG ALVEOLUS DEVELOPMENT 12 41 0.0009033 0.007798
540 ACTIN FILAMENT BASED PROCESS 70 450 0.0009054 0.007799
541 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 41 232 0.0009068 0.007799
542 MULTICELLULAR ORGANISM GROWTH 18 76 0.0009216 0.007912
543 REGULATION OF PHOSPHOLIPASE ACTIVITY 16 64 0.0009367 0.008011
544 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 17 70 0.0009364 0.008011
545 POSITIVE REGULATION OF NEURON DIFFERENTIATION 51 306 0.000945 0.008068
546 CELL CELL ADHESION 90 608 0.0009516 0.00811
547 POSITIVE REGULATION OF PROTEIN SECRETION 38 211 0.0009538 0.008114
548 TRANSITION METAL ION TRANSPORT 23 108 0.0009639 0.00817
549 REGULATION OF MEMBRANE PROTEIN ECTODOMAIN PROTEOLYSIS 8 21 0.0009693 0.00817
550 CELLULAR BIOGENIC AMINE CATABOLIC PROCESS 8 21 0.0009693 0.00817
551 AMINE CATABOLIC PROCESS 8 21 0.0009693 0.00817
552 FIBRINOLYSIS 8 21 0.0009693 0.00817
553 SINGLE ORGANISM CELL ADHESION 71 459 0.0009761 0.008198
554 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 45 262 0.0009752 0.008198
555 AMMONIUM ION METABOLIC PROCESS 32 169 0.0009868 0.008236
556 REGULATION OF BLOOD PRESSURE 32 169 0.0009868 0.008236
557 REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 11 36 0.0009877 0.008236
558 POSITIVE REGULATION OF GLUCOSE METABOLIC PROCESS 11 36 0.0009877 0.008236
559 NEGATIVE REGULATION OF GENE EXPRESSION 197 1493 0.000999 0.008308
560 REGULATION OF PH 20 89 0.001002 0.008308
561 RESPONSE TO GROWTH FACTOR 73 475 0.001002 0.008308
562 REGULATION OF PROTEIN TARGETING 51 307 0.001018 0.008427
563 ORGAN REGENERATION 19 83 0.001047 0.008627
564 EMBRYONIC PLACENTA DEVELOPMENT 19 83 0.001047 0.008627
565 MESODERMAL CELL DIFFERENTIATION 9 26 0.001049 0.008627
566 INACTIVATION OF MAPK ACTIVITY 9 26 0.001049 0.008627
567 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 68 437 0.001054 0.008646
568 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 25 122 0.00107 0.008768
569 REGULATION OF TRANSPORTER ACTIVITY 36 198 0.001072 0.008769
570 NEURON PROJECTION EXTENSION 14 53 0.001075 0.008778
571 BONE DEVELOPMENT 30 156 0.00108 0.008782
572 CELLULAR RESPONSE TO INORGANIC SUBSTANCE 30 156 0.00108 0.008782
573 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 35 191 0.001082 0.00879
574 REGULATION OF CATABOLIC PROCESS 105 731 0.001085 0.008791
575 REACTIVE OXYGEN SPECIES METABOLIC PROCESS 21 96 0.001097 0.008874
576 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 117 829 0.001109 0.008963
577 MODULATION OF SYNAPTIC TRANSMISSION 50 301 0.001135 0.009153
578 AUTONOMIC NERVOUS SYSTEM DEVELOPMENT 12 42 0.001143 0.009184
579 SERINE FAMILY AMINO ACID METABOLIC PROCESS 12 42 0.001143 0.009184
580 INFLAMMATORY RESPONSE 70 454 0.001151 0.009237
581 SODIUM ION TRANSMEMBRANE TRANSPORT 20 90 0.00116 0.009293
582 REGULATION OF CIRCADIAN RHYTHM 22 103 0.00118 0.009418
583 REGULATION OF PLATELET AGGREGATION 7 17 0.001184 0.009418
584 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 22 103 0.00118 0.009418
585 PARASYMPATHETIC NERVOUS SYSTEM DEVELOPMENT 7 17 0.001184 0.009418
586 NEGATIVE REGULATION OF KINASE ACTIVITY 43 250 0.001211 0.009619
587 REGULATION OF CYTOSKELETON ORGANIZATION 76 502 0.001225 0.009714
588 NEURON MIGRATION 23 110 0.001252 0.00991
589 GLAND MORPHOGENESIS 21 97 0.001261 0.009961
NumGOOverlapSizeP ValueAdj. P Value
1 COFACTOR BINDING 69 263 9.868e-13 9.167e-10
2 CYTOSKELETAL PROTEIN BINDING 146 819 3.111e-10 1.293e-07
3 IDENTICAL PROTEIN BINDING 198 1209 4.175e-10 1.293e-07
4 OXIDOREDUCTASE ACTIVITY 128 719 4.362e-09 1.013e-06
5 TRANSITION METAL ION BINDING 216 1400 1.22e-08 1.889e-06
6 LIPID BINDING 118 657 1.061e-08 1.889e-06
7 KINASE ACTIVITY 142 842 2.268e-08 3.01e-06
8 MONOOXYGENASE ACTIVITY 30 95 2.879e-08 3.343e-06
9 PROTEIN DIMERIZATION ACTIVITY 179 1149 1.22e-07 1.259e-05
10 PYRIDOXAL PHOSPHATE BINDING 20 52 1.556e-07 1.314e-05
11 RECEPTOR BINDING 220 1476 1.483e-07 1.314e-05
12 PROTEIN HOMODIMERIZATION ACTIVITY 122 722 2.034e-07 1.575e-05
13 RIBONUCLEOTIDE BINDING 265 1860 3.929e-07 2.808e-05
14 METAL ION TRANSMEMBRANE TRANSPORTER ACTIVITY 78 417 6.518e-07 4.325e-05
15 OXIDOREDUCTASE ACTIVITY ACTING ON PAIRED DONORS WITH INCORPORATION OR REDUCTION OF MOLECULAR OXYGEN 38 155 7.706e-07 4.773e-05
16 PROTEIN COMPLEX BINDING 147 935 1.011e-06 5.87e-05
17 TETRAPYRROLE BINDING 34 134 1.249e-06 6.825e-05
18 TRANSMEMBRANE TRANSPORTER ACTIVITY 154 997 1.604e-06 7.844e-05
19 ADENYL NUCLEOTIDE BINDING 219 1514 1.521e-06 7.844e-05
20 COENZYME BINDING 41 179 1.924e-06 8.939e-05
21 IRON ION BINDING 38 163 2.876e-06 0.0001206
22 TRANSPORTER ACTIVITY 188 1276 2.744e-06 0.0001206
23 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 152 992 2.986e-06 0.0001206
24 MACROMOLECULAR COMPLEX BINDING 202 1399 4.513e-06 0.0001747
25 SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 33 136 5.087e-06 0.000189
26 STEROID HYDROXYLASE ACTIVITY 13 31 7.619e-06 0.0002722
27 MONOSACCHARIDE BINDING 21 70 8.297e-06 0.0002855
28 GROWTH FACTOR BINDING 30 123 1.204e-05 0.0003995
29 CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 101 622 1.315e-05 0.0004213
30 OXIDOREDUCTASE ACTIVITY ACTING ON PAIRED DONORS WITH INCORPORATION OR REDUCTION OF MOLECULAR OXYGEN NAD P H AS ONE DONOR AND INCORPORATION OF ONE ATOM OF OXYGEN 14 37 1.417e-05 0.0004389
31 SULFUR COMPOUND BINDING 47 234 1.613e-05 0.0004834
32 ORGANIC ACID BINDING 43 209 1.979e-05 0.0005746
33 TRANSCRIPTION FACTOR ACTIVITY DIRECT LIGAND REGULATED SEQUENCE SPECIFIC DNA BINDING 16 48 2.27e-05 0.0006392
34 ACTIVE TRANSMEMBRANE TRANSPORTER ACTIVITY 64 356 2.349e-05 0.0006419
35 INORGANIC CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 87 527 2.766e-05 0.0007341
36 KINASE BINDING 97 606 3.46e-05 0.0008773
37 OXIDOREDUCTASE ACTIVITY ACTING ON PAIRED DONORS WITH INCORPORATION OR REDUCTION OF MOLECULAR OXYGEN REDUCED FLAVIN OR FLAVOPROTEIN AS ONE DONOR AND INCORPORATION OF ONE ATOM OF OXYGEN 11 26 3.494e-05 0.0008773
38 ENZYME BINDING 237 1737 3.759e-05 0.0009189
39 PROTEIN KINASE ACTIVITY 101 640 4.288e-05 0.0009959
40 ZINC ION BINDING 166 1155 4.258e-05 0.0009959
41 MOLECULAR FUNCTION REGULATOR 190 1353 4.678e-05 0.001059
42 GLYCOPROTEIN BINDING 25 101 4.789e-05 0.001059
43 APOLIPOPROTEIN BINDING 8 15 5.532e-05 0.001195
44 ORGANIC ANION TRANSMEMBRANE TRANSPORTER ACTIVITY 37 178 5.793e-05 0.001223
45 PHOSPHATIDYLINOSITOL BINDING 40 200 7.356e-05 0.001519
46 GLYCOSAMINOGLYCAN BINDING 40 205 0.0001289 0.002603
47 TRANSITION METAL ION TRANSMEMBRANE TRANSPORTER ACTIVITY 13 39 0.0001318 0.002605
48 ACTIN BINDING 66 393 0.0001486 0.002858
49 KINASE REGULATOR ACTIVITY 37 186 0.0001508 0.002858
50 OXIDIZED NAD BINDING 7 13 0.0001539 0.00286
51 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 57 328 0.0001643 0.002993
52 PROTEIN BINDING INVOLVED IN CELL ADHESION 8 17 0.0001716 0.003065
53 TRANSCRIPTION FACTOR BINDING 83 524 0.0001766 0.003095
54 ANION TRANSMEMBRANE TRANSPORTER ACTIVITY 52 293 0.0001827 0.003144
55 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 34 168 0.0001946 0.003288
56 PHOSPHATIDYLINOSITOL PHOSPHATE BINDING 26 116 0.0001993 0.003299
57 CARBON CARBON LYASE ACTIVITY 15 51 0.0002024 0.003299
58 ORGANIC ACID TRANSMEMBRANE TRANSPORTER ACTIVITY 30 142 0.0002067 0.003311
59 OXIDOREDUCTASE ACTIVITY ACTING ON THE CH CH GROUP OF DONORS 16 57 0.0002289 0.00357
60 FATTY ACYL COA BINDING 11 31 0.0002306 0.00357
61 ION CHANNEL BINDING 25 111 0.000242 0.003685
62 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 24 105 0.0002524 0.003781
63 FILAMIN BINDING 7 14 0.0002793 0.004104
64 OXYGEN BINDING 14 47 0.0002827 0.004104
65 ANION CATION SYMPORTER ACTIVITY 15 53 0.0003228 0.004613
66 STEROID HORMONE RECEPTOR ACTIVITY 16 59 0.0003526 0.00486
67 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 95 629 0.0003529 0.00486
68 PHOSPHOLIPID BINDING 60 360 0.0003558 0.00486
69 TRANSFERASE ACTIVITY TRANSFERRING NITROGENOUS GROUPS 9 23 0.0003696 0.004933
70 ENZYME REGULATOR ACTIVITY 136 959 0.0003717 0.004933
71 PROTEIN BINDING INVOLVED IN CELL CELL ADHESION 6 11 0.0004318 0.005571
72 SEMAPHORIN RECEPTOR ACTIVITY 6 11 0.0004318 0.005571
73 SYMPORTER ACTIVITY 29 142 0.0004743 0.006036
74 SECONDARY ACTIVE TRANSMEMBRANE TRANSPORTER ACTIVITY 42 233 0.0005224 0.006558
75 MONOVALENT INORGANIC CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 60 366 0.0005498 0.00681
76 PROTEIN SERINE THREONINE KINASE ACTIVITY 70 445 0.0006645 0.008123
77 SOLUTE CATION SYMPORTER ACTIVITY 22 99 0.0006753 0.008147
78 EXTRACELLULAR MATRIX BINDING 14 51 0.0007096 0.008451
79 SODIUM AMINO ACID SYMPORTER ACTIVITY 6 12 0.0007853 0.009006
80 ORGANIC ACID SODIUM SYMPORTER ACTIVITY 10 30 0.0007819 0.009006
81 CATION AMINO ACID SYMPORTER ACTIVITY 7 16 0.0007671 0.009006
NumGOOverlapSizeP ValueAdj. P Value
1 NEURON PART 217 1265 5.812e-13 3.394e-10
2 MEMBRANE REGION 198 1134 1.258e-12 3.673e-10
3 INTRINSIC COMPONENT OF PLASMA MEMBRANE 264 1649 4.396e-12 8.558e-10
4 CELL JUNCTION 193 1151 9.483e-11 1.127e-08
5 PLASMA MEMBRANE REGION 163 929 9.645e-11 1.127e-08
6 NEURON PROJECTION 164 942 1.553e-10 1.512e-08
7 SYNAPSE 137 754 3.038e-10 2.534e-08
8 CELL SURFACE 137 757 3.998e-10 2.918e-08
9 ENDOPLASMIC RETICULUM 248 1631 3.511e-09 2.278e-07
10 APICAL PART OF CELL 74 361 2.88e-08 1.682e-06
11 SYNAPSE PART 109 610 5.118e-08 2.717e-06
12 MEMBRANE MICRODOMAIN 62 288 5.975e-08 2.908e-06
13 APICAL PLASMA MEMBRANE 61 292 2.332e-07 9.844e-06
14 SOMATODENDRITIC COMPARTMENT 112 650 2.36e-07 9.844e-06
15 CELL PROJECTION 257 1786 2.627e-07 1.023e-05
16 ENDOPLASMIC RETICULUM PART 178 1163 4.446e-07 1.623e-05
17 CELL CELL JUNCTION 73 383 7.103e-07 2.44e-05
18 MICROBODY 34 134 1.249e-06 4.052e-05
19 MICROBODY PART 26 93 3.183e-06 9.785e-05
20 NUCLEAR OUTER MEMBRANE ENDOPLASMIC RETICULUM MEMBRANE NETWORK 153 1005 4.005e-06 0.000117
21 AXON PART 46 219 5.844e-06 0.0001625
22 PROTEINACEOUS EXTRACELLULAR MATRIX 66 356 6.276e-06 0.0001666
23 DENDRITE 79 451 7.477e-06 0.0001899
24 AXON 74 418 9.835e-06 0.0002393
25 SIDE OF MEMBRANE 75 428 1.243e-05 0.0002605
26 RECEPTOR COMPLEX 61 327 1.138e-05 0.0002605
27 CELL BODY 84 494 1.249e-05 0.0002605
28 CELL PROJECTION PART 143 946 1.208e-05 0.0002605
29 EXTRACELLULAR MATRIX 74 426 1.928e-05 0.0003882
30 VACUOLE 171 1180 2.055e-05 4e-04
31 EXTRACELLULAR SPACE 195 1376 2.143e-05 0.0004037
32 PRESYNAPSE 52 283 7.357e-05 0.001343
33 MICROBODY MEMBRANE 17 58 8.164e-05 0.001368
34 PERINUCLEAR REGION OF CYTOPLASM 100 642 7.819e-05 0.001368
35 POSTSYNAPSE 65 378 8.213e-05 0.001368
36 MITOCHONDRION 222 1633 8.43e-05 0.001368
37 EXTERNAL SIDE OF PLASMA MEMBRANE 45 238 0.0001101 0.001738
38 BRUSH BORDER 24 102 0.0001576 0.002423
39 NEURON PROJECTION TERMINUS 28 129 0.0002062 0.003087
40 ACTIN CYTOSKELETON 72 444 0.0002282 0.003332
41 BASOLATERAL PLASMA MEMBRANE 40 211 0.0002433 0.003466
42 PLATELET ALPHA GRANULE 19 75 0.0002705 0.003761
43 CYTOSKELETON 257 1967 0.000313 0.004106
44 PLASMA MEMBRANE PROTEIN COMPLEX 80 510 0.0003129 0.004106
45 ANCHORED COMPONENT OF MEMBRANE 31 152 0.0003164 0.004106
46 CLUSTER OF ACTIN BASED CELL PROJECTIONS 29 139 0.0003268 0.004148
47 ANCHORING JUNCTION 77 489 0.000357 0.004436
48 ACTIN BASED CELL PROJECTION 35 181 0.0003928 0.004778
49 PLASMA MEMBRANE RECEPTOR COMPLEX 34 175 0.0004313 0.005043
50 SEMAPHORIN RECEPTOR COMPLEX 6 11 0.0004318 0.005043
51 ENDOSOME 115 793 0.0004492 0.005144
52 PLATELET ALPHA GRANULE LUMEN 15 55 5e-04 0.005615
53 TRANSPORT VESICLE 56 338 0.0006361 0.007009
54 AXONAL GROWTH CONE 8 20 0.0006618 0.007157
55 EXTRINSIC COMPONENT OF MEMBRANE 44 252 0.0007806 0.008289
56 CELL LEADING EDGE 57 350 0.0008762 0.009138
57 NEURON SPINE 25 121 0.0009455 0.009358
58 MAIN AXON 15 58 0.0009182 0.009358
59 TERMINAL BOUTON 16 64 0.0009367 0.009358

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04810_Regulation_of_actin_cytoskeleton 41 387 0.5569 1
2 hsa04010_MAPK_signaling_pathway 40 387 0.622 1
3 hsa04510_Focal_adhesion 38 387 0.742 1
4 hsa04360_Axon_guidance 29 387 0.9876 1
5 hsa04610_Complement_and_coagulation_cascades 26 387 0.9975 1
6 hsa04910_Insulin_signaling_pathway 25 387 0.9986 1
7 hsa04020_Calcium_signaling_pathway 24 387 0.9993 1
8 hsa03320_PPAR_signaling_pathway 23 387 0.9997 1
9 hsa04062_Chemokine_signaling_pathway 23 387 0.9997 1
10 hsa04380_Osteoclast_differentiation 22 387 0.9998 1
11 hsa04514_Cell_adhesion_molecules_.CAMs. 22 387 0.9998 1
12 hsa04630_Jak.STAT_signaling_pathway 22 387 0.9998 1
13 hsa04146_Peroxisome 21 387 0.9999 1
14 hsa04920_Adipocytokine_signaling_pathway 21 387 0.9999 1
15 hsa04974_Protein_digestion_and_absorption 21 387 0.9999 1
16 hsa00010_Glycolysis_._Gluconeogenesis 15 387 1 1
17 hsa00020_Citrate_cycle_.TCA_cycle. 6 387 1 1
18 hsa00030_Pentose_phosphate_pathway 6 387 1 1
19 hsa00040_Pentose_and_glucuronate_interconversions 6 387 1 1
20 hsa00051_Fructose_and_mannose_metabolism 8 387 1 1
21 hsa00052_Galactose_metabolism 7 387 1 1
22 hsa00053_Ascorbate_and_aldarate_metabolism 5 387 1 1
23 hsa00061_Fatty_acid_biosynthesis 3 387 1 1
24 hsa00071_Fatty_acid_metabolism 18 387 1 1
25 hsa00072_Synthesis_and_degradation_of_ketone_bodies 3 387 1 1
26 hsa00120_Primary_bile_acid_biosynthesis 10 387 1 1
27 hsa00140_Steroid_hormone_biosynthesis 14 387 1 1
28 hsa00190_Oxidative_phosphorylation 8 387 1 1
29 hsa00230_Purine_metabolism 17 387 1 1
30 hsa00240_Pyrimidine_metabolism 13 387 1 1
31 hsa00250_Alanine._aspartate_and_glutamate_metabolism 12 387 1 1
32 hsa00260_Glycine._serine_and_threonine_metabolism 14 387 1 1
33 hsa00270_Cysteine_and_methionine_metabolism 9 387 1 1
34 hsa00280_Valine._leucine_and_isoleucine_degradation 19 387 1 1
35 hsa00290_Valine._leucine_and_isoleucine_biosynthesis 2 387 1 1
36 hsa00300_Lysine_biosynthesis 2 387 1 1
37 hsa00310_Lysine_degradation 12 387 1 1
38 hsa00330_Arginine_and_proline_metabolism 14 387 1 1
39 hsa00340_Histidine_metabolism 8 387 1 1
40 hsa00350_Tyrosine_metabolism 9 387 1 1
41 hsa00360_Phenylalanine_metabolism 7 387 1 1
42 hsa00380_Tryptophan_metabolism 13 387 1 1
43 hsa00400_Phenylalanine._tyrosine_and_tryptophan_biosynthesis 4 387 1 1
44 hsa00410_beta.Alanine_metabolism 9 387 1 1
45 hsa00430_Taurine_and_hypotaurine_metabolism 4 387 1 1
46 hsa00450_Selenocompound_metabolism 3 387 1 1
47 hsa00471_D.Glutamine_and_D.glutamate_metabolism 2 387 1 1
48 hsa00480_Glutathione_metabolism 6 387 1 1
49 hsa00500_Starch_and_sucrose_metabolism 14 387 1 1
50 hsa00510_N.Glycan_biosynthesis 5 387 1 1
51 hsa00511_Other_glycan_degradation 2 387 1 1
52 hsa00512_Mucin_type_O.Glycan_biosynthesis 5 387 1 1
53 hsa00514_Other_types_of_O.glycan_biosynthesis 6 387 1 1
54 hsa00520_Amino_sugar_and_nucleotide_sugar_metabolism 7 387 1 1
55 hsa00531_Glycosaminoglycan_degradation 2 387 1 1
56 hsa00533_Glycosaminoglycan_biosynthesis_._keratan_sulfate 4 387 1 1
57 hsa00534_Glycosaminoglycan_biosynthesis_._heparan_sulfate 4 387 1 1
58 hsa00561_Glycerolipid_metabolism 15 387 1 1
59 hsa00562_Inositol_phosphate_metabolism 9 387 1 1
60 hsa00563_Glycosylphosphatidylinositol.GPI..anchor_biosynthesis 3 387 1 1
61 hsa00564_Glycerophospholipid_metabolism 13 387 1 1
62 hsa00565_Ether_lipid_metabolism 3 387 1 1
63 hsa00590_Arachidonic_acid_metabolism 14 387 1 1
64 hsa00591_Linoleic_acid_metabolism 9 387 1 1
65 hsa00592_alpha.Linolenic_acid_metabolism 3 387 1 1
66 hsa00600_Sphingolipid_metabolism 4 387 1 1
67 hsa00601_Glycosphingolipid_biosynthesis_._lacto_and_neolacto_series 5 387 1 1
68 hsa00603_Glycosphingolipid_biosynthesis_._globo_series 3 387 1 1
69 hsa00604_Glycosphingolipid_biosynthesis_._ganglio_series 3 387 1 1
70 hsa00620_Pyruvate_metabolism 10 387 1 1
71 hsa00630_Glyoxylate_and_dicarboxylate_metabolism 5 387 1 1
72 hsa00640_Propanoate_metabolism 11 387 1 1
73 hsa00650_Butanoate_metabolism 10 387 1 1
74 hsa00670_One_carbon_pool_by_folate 3 387 1 1
75 hsa00740_Riboflavin_metabolism 2 387 1 1
76 hsa00750_Vitamin_B6_metabolism 3 387 1 1
77 hsa00760_Nicotinate_and_nicotinamide_metabolism 6 387 1 1
78 hsa00770_Pantothenate_and_CoA_biosynthesis 7 387 1 1
79 hsa00790_Folate_biosynthesis 2 387 1 1
80 hsa00830_Retinol_metabolism 19 387 1 1
81 hsa00860_Porphyrin_and_chlorophyll_metabolism 6 387 1 1
82 hsa00900_Terpenoid_backbone_biosynthesis 4 387 1 1
83 hsa00910_Nitrogen_metabolism 6 387 1 1
84 hsa00920_Sulfur_metabolism 2 387 1 1
85 hsa00970_Aminoacyl.tRNA_biosynthesis 2 387 1 1
86 hsa00980_Metabolism_of_xenobiotics_by_cytochrome_P450 18 387 1 1
87 hsa00982_Drug_metabolism_._cytochrome_P450 19 387 1 1
88 hsa00983_Drug_metabolism_._other_enzymes 13 387 1 1
89 hsa01040_Biosynthesis_of_unsaturated_fatty_acids 8 387 1 1
90 hsa02010_ABC_transporters 12 387 1 1
91 hsa03008_Ribosome_biogenesis_in_eukaryotes 6 387 1 1
92 hsa03013_RNA_transport 8 387 1 1
93 hsa03015_mRNA_surveillance_pathway 8 387 1 1
94 hsa03018_RNA_degradation 6 387 1 1
95 hsa03020_RNA_polymerase 2 387 1 1
96 hsa03030_DNA_replication 2 387 1 1
97 hsa03040_Spliceosome 8 387 1 1
98 hsa03410_Base_excision_repair 2 387 1 1
99 hsa03440_Homologous_recombination 4 387 1 1
100 hsa04012_ErbB_signaling_pathway 17 387 1 1
101 hsa04070_Phosphatidylinositol_signaling_system 15 387 1 1
102 hsa04110_Cell_cycle 19 387 1 1
103 hsa04114_Oocyte_meiosis 15 387 1 1
104 hsa04115_p53_signaling_pathway 20 387 1 1
105 hsa04120_Ubiquitin_mediated_proteolysis 9 387 1 1
106 hsa04130_SNARE_interactions_in_vesicular_transport 3 387 1 1
107 hsa04140_Regulation_of_autophagy 3 387 1 1
108 hsa04141_Protein_processing_in_endoplasmic_reticulum 13 387 1 1
109 hsa04142_Lysosome 10 387 1 1
110 hsa04144_Endocytosis 19 387 1 1
111 hsa04145_Phagosome 20 387 1 1
112 hsa04150_mTOR_signaling_pathway 7 387 1 1
113 hsa04210_Apoptosis 16 387 1 1
114 hsa04260_Cardiac_muscle_contraction 4 387 1 1
115 hsa04270_Vascular_smooth_muscle_contraction 18 387 1 1
116 hsa04310_Wnt_signaling_pathway 20 387 1 1
117 hsa04320_Dorso.ventral_axis_formation 5 387 1 1
118 hsa04330_Notch_signaling_pathway 2 387 1 1
119 hsa04340_Hedgehog_signaling_pathway 5 387 1 1
120 hsa04350_TGF.beta_signaling_pathway 16 387 1 1
121 hsa04370_VEGF_signaling_pathway 13 387 1 1
122 hsa04512_ECM.receptor_interaction 19 387 1 1
123 hsa04520_Adherens_junction 10 387 1 1
124 hsa04530_Tight_junction 19 387 1 1
125 hsa04540_Gap_junction 13 387 1 1
126 hsa04612_Antigen_processing_and_presentation 6 387 1 1
127 hsa04614_Renin.angiotensin_system 8 387 1 1
128 hsa04620_Toll.like_receptor_signaling_pathway 16 387 1 1
129 hsa04621_NOD.like_receptor_signaling_pathway 6 387 1 1
130 hsa04622_RIG.I.like_receptor_signaling_pathway 5 387 1 1
131 hsa04623_Cytosolic_DNA.sensing_pathway 2 387 1 1
132 hsa04640_Hematopoietic_cell_lineage 14 387 1 1
133 hsa04650_Natural_killer_cell_mediated_cytotoxicity 18 387 1 1
134 hsa04660_T_cell_receptor_signaling_pathway 15 387 1 1
135 hsa04662_B_cell_receptor_signaling_pathway 11 387 1 1
136 hsa04664_Fc_epsilon_RI_signaling_pathway 16 387 1 1
137 hsa04666_Fc_gamma_R.mediated_phagocytosis 18 387 1 1
138 hsa04670_Leukocyte_transendothelial_migration 14 387 1 1
139 hsa04672_Intestinal_immune_network_for_IgA_production 4 387 1 1
140 hsa04710_Circadian_rhythm_._mammal 6 387 1 1
141 hsa04720_Long.term_potentiation 9 387 1 1
142 hsa04722_Neurotrophin_signaling_pathway 19 387 1 1
143 hsa04730_Long.term_depression 12 387 1 1
144 hsa04740_Olfactory_transduction 3 388 1 1
145 hsa04742_Taste_transduction 3 387 1 1
146 hsa04912_GnRH_signaling_pathway 16 387 1 1
147 hsa04914_Progesterone.mediated_oocyte_maturation 14 387 1 1
148 hsa04916_Melanogenesis 15 387 1 1
149 hsa04960_Aldosterone.regulated_sodium_reabsorption 9 387 1 1
150 hsa04962_Vasopressin.regulated_water_reabsorption 4 387 1 1
151 hsa04964_Proximal_tubule_bicarbonate_reclamation 7 387 1 1
152 hsa04966_Collecting_duct_acid_secretion 5 387 1 1
153 hsa04970_Salivary_secretion 12 387 1 1
154 hsa04971_Gastric_acid_secretion 11 387 1 1
155 hsa04972_Pancreatic_secretion 14 387 1 1
156 hsa04973_Carbohydrate_digestion_and_absorption 6 387 1 1
157 hsa04975_Fat_digestion_and_absorption 9 387 1 1
158 hsa04976_Bile_secretion 19 387 1 1
159 hsa04977_Vitamin_digestion_and_absorption 6 387 1 1

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1

FAM201A

 hsa-miR-100-3p;hsa-miR-105-5p;hsa-miR-1178-3p;hsa-miR-1271-5p;hsa-miR-1299;hsa-miR-135b-5p;hsa-miR-147a;hsa-miR-149-5p;hsa-miR-558;hsa-miR-561-3p;hsa-miR-708-5p 11 CACNA1E Sponge network 0.028 0.75302 0.17 0.40772 0.755
2 SNX29P2 hsa-miR-1237-3p;hsa-miR-125a-5p;hsa-miR-133a-3p;hsa-miR-141-3p;hsa-miR-142-3p;hsa-miR-145-5p;hsa-miR-146a-5p;hsa-miR-200a-3p;hsa-miR-21-5p;hsa-miR-544a 10 EGFR Sponge network 0.195 0.26721 -0.075 0.75424 0.581
3

FAM201A

 hsa-miR-147a;hsa-miR-217;hsa-miR-326;hsa-miR-506-3p;hsa-miR-509-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-607;hsa-miR-641;hsa-miR-7-1-3p 10 AKAP6 Sponge network 0.028 0.75302 0.08 0.08966 0.54
4

CCDC26

 hsa-miR-1255a;hsa-miR-1270;hsa-miR-1291;hsa-miR-1304-5p;hsa-miR-141-3p;hsa-miR-1538;hsa-miR-1911-3p;hsa-miR-448;hsa-miR-507;hsa-miR-590-3p;hsa-miR-641;hsa-miR-661 12 CLYBL Sponge network 0.054 0.50959 0.345 0.14058 0.5
5

CCDC26

 hsa-miR-1200;hsa-miR-1256;hsa-miR-1257;hsa-miR-1262;hsa-miR-1271-5p;hsa-miR-1294;hsa-miR-1305;hsa-miR-141-3p;hsa-miR-199b-5p;hsa-miR-548n;hsa-miR-548o-3p 11 ZNF618 Sponge network 0.054 0.50959 0.083 0.11003 0.483
6

CCDC26

 hsa-miR-105-5p;hsa-miR-1299;hsa-miR-133a-3p;hsa-miR-141-3p;hsa-miR-142-3p;hsa-miR-155-5p;hsa-miR-182-3p;hsa-miR-29b-2-5p;hsa-miR-302e;hsa-miR-620 10 EGFR Sponge network 0.054 0.50959 -0.075 0.75424 0.45
7

CCDC26

 hsa-miR-1224-5p;hsa-miR-1226-3p;hsa-miR-1271-5p;hsa-miR-1294;hsa-miR-150-5p;hsa-miR-200c-3p;hsa-miR-206;hsa-miR-31-5p;hsa-miR-541-5p;hsa-miR-661 10 NDST1 Sponge network 0.054 0.50959 0.015 0.85538 0.416
8

CCDC26

 hsa-miR-1253;hsa-miR-126-5p;hsa-miR-1290;hsa-miR-1297;hsa-miR-1299;hsa-miR-1305;hsa-miR-181d-5p;hsa-miR-200a-5p;hsa-miR-302e;hsa-miR-548a-5p;hsa-miR-548e-3p;hsa-miR-548h-5p 12 MCC Sponge network 0.054 0.50959 0.041 0.8141 0.415

Quest ID: 49a5c3181e7f7d5b5be6a1c033acb249