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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-106a-5p KAT2B -0.46 0.00972 -0.94 0 MirTarget -0.18 1.0E-5 NA
2 hsa-miR-106b-5p KAT2B 0.65 0 -0.94 0 miRNAWalker2 validate; miRTarBase; MirTarget -0.52 0 NA
3 hsa-miR-125a-3p KAT2B -0.84 4.0E-5 -0.94 0 miRanda -0.15 4.0E-5 NA
4 hsa-miR-17-5p KAT2B 0.7 2.0E-5 -0.94 0 MirTarget; TargetScan -0.4 0 23095762 miR 17 5p targets the p300/CBP associated factor and modulates androgen receptor transcriptional activity in cultured prostate cancer cells; Targeting of PCAF by miR-17-5p was evaluated using the luciferase reporter assay; Expression of PCAF in PCa cells was associated with the downregulation of miR-17-5p; Targeting of the 3'-untranslated region of PCAF mRNA by miR-17-5p caused translational suppression and RNA degradation and consequently modulation of AR transcriptional activity in PCa cells; PCAF is upregulated in cultured PCa cells and upregulation of PCAF is associated with the downregulation of miR-17-5p; Targeting of PCAF by miR-17-5p modulates AR transcriptional activity and cell growth in cultured PCa cells
5 hsa-miR-181a-5p KAT2B 0.25 0.05519 -0.94 0 miRNAWalker2 validate; miRTarBase; MirTarget -0.43 0 NA
6 hsa-miR-181b-5p KAT2B 0.49 0.00105 -0.94 0 miRNAWalker2 validate; miRTarBase; MirTarget -0.46 0 NA
7 hsa-miR-181c-5p KAT2B -0.01 0.96913 -0.94 0 MirTarget -0.27 0 NA
8 hsa-miR-181d-5p KAT2B 0.16 0.36381 -0.94 0 MirTarget -0.28 0 NA
9 hsa-miR-19a-3p KAT2B 1.02 0 -0.94 0 miRNAWalker2 validate -0.26 0 NA
10 hsa-miR-19b-3p KAT2B 0.6 0.00017 -0.94 0 miRNAWalker2 validate -0.3 0 NA
11 hsa-miR-20a-3p KAT2B -0.32 0.04679 -0.94 0 MirTarget -0.22 0 NA
12 hsa-miR-20a-5p KAT2B 0.85 0 -0.94 0 MirTarget -0.32 0 NA
13 hsa-miR-20b-5p KAT2B 0.46 0.02859 -0.94 0 MirTarget -0.11 0.00122 NA
14 hsa-miR-25-3p KAT2B 0.63 0 -0.94 0 miRNAWalker2 validate; miRTarBase; MirTarget -0.26 0.00023 NA
15 hsa-miR-330-3p KAT2B -0.33 0.03161 -0.94 0 MirTarget -0.27 0 NA
16 hsa-miR-338-5p KAT2B -0.22 0.25239 -0.94 0 MirTarget; miRNATAP -0.15 7.0E-5 NA
17 hsa-miR-342-3p KAT2B -0.32 0.04498 -0.94 0 miRanda -0.18 7.0E-5 NA
18 hsa-miR-363-3p KAT2B -0.17 0.37519 -0.94 0 MirTarget -0.1 0.00633 NA
19 hsa-miR-429 KAT2B -1.4 7.0E-5 -0.94 0 miRanda -0.13 0 NA
20 hsa-miR-590-5p KAT2B -0.1 0.31003 -0.94 0 miRanda -0.26 0.0004 NA
21 hsa-miR-92a-3p KAT2B 0.21 0.13429 -0.94 0 miRNAWalker2 validate; MirTarget -0.35 0 NA
22 hsa-miR-92b-3p KAT2B 0.22 0.29619 -0.94 0 MirTarget -0.23 0 NA
23 hsa-miR-93-5p KAT2B 1.4 0 -0.94 0 miRNAWalker2 validate; miRTarBase; MirTarget -0.38 0 NA
NumGOOverlapSizeP ValueAdj. P Value
1 CHROMOSOME ORGANIZATION 101 1009 2.097e-38 4.878e-35
2 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 135 1784 1.405e-38 4.878e-35
3 POSITIVE REGULATION OF GENE EXPRESSION 128 1733 2.817e-35 4.37e-32
4 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 130 1805 9.465e-35 1.101e-31
5 NEGATIVE REGULATION OF GENE EXPRESSION 113 1493 9.484e-32 7.36e-29
6 CHROMATIN ORGANIZATION 75 663 9.491e-32 7.36e-29
7 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 112 1517 1.744e-30 1.159e-27
8 CELL CYCLE 100 1316 5.108e-28 2.971e-25
9 CHROMATIN MODIFICATION 63 539 1.84e-27 9.511e-25
10 CELLULAR RESPONSE TO DNA DAMAGE STIMULUS 70 720 1.31e-25 6.096e-23
11 DNA METABOLIC PROCESS 71 758 5.296e-25 2.24e-22
12 MITOTIC CELL CYCLE 71 766 9.908e-25 3.842e-22
13 CELL CYCLE PROCESS 85 1081 1.111e-24 3.975e-22
14 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 81 1004 3.187e-24 1.059e-21
15 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 68 740 1.781e-23 5.524e-21
16 CELLULAR RESPONSE TO STRESS 102 1565 2.345e-23 6.819e-21
17 REGULATION OF CELL CYCLE 77 949 3.618e-23 9.902e-21
18 REGULATION OF BINDING 42 283 1.562e-22 4.037e-20
19 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 65 724 6.633e-22 1.624e-19
20 COVALENT CHROMATIN MODIFICATION 44 345 7.073e-21 1.646e-18
21 REGULATION OF CHROMOSOME ORGANIZATION 39 278 4.223e-20 9.356e-18
22 REGULATION OF CELL CYCLE PROCESS 54 558 9.321e-20 1.971e-17
23 REGULATION OF ORGANELLE ORGANIZATION 80 1178 2.872e-19 5.811e-17
24 CELL CYCLE CHECKPOINT 32 194 7.955e-19 1.542e-16
25 CHROMATIN REMODELING 28 150 4.274e-18 7.955e-16
26 REGULATION OF MITOTIC CELL CYCLE 47 468 6.101e-18 1.092e-15
27 CELL CYCLE PHASE TRANSITION 35 255 7.652e-18 1.319e-15
28 PEPTIDYL AMINO ACID MODIFICATION 63 841 2.834e-17 4.709e-15
29 REGULATION OF DNA METABOLIC PROCESS 39 340 5.221e-17 8.377e-15
30 REGULATION OF CELL PROLIFERATION 87 1496 1.013e-16 1.571e-14
31 NEGATIVE REGULATION OF CELL CYCLE PROCESS 31 214 1.3e-16 1.927e-14
32 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 30 199 1.325e-16 1.927e-14
33 POSITIVE REGULATION OF CELL CYCLE 38 332 1.438e-16 2.027e-14
34 NEGATIVE REGULATION OF CELL CYCLE 43 433 2.565e-16 3.51e-14
35 REGULATION OF CELL CYCLE PHASE TRANSITION 37 321 2.917e-16 3.878e-14
36 POSITIVE REGULATION OF CELL CYCLE PROCESS 32 247 1.12e-15 1.448e-13
37 DNA INTEGRITY CHECKPOINT 25 146 2.268e-15 2.852e-13
38 DNA CONFORMATION CHANGE 33 273 3.109e-15 3.807e-13
39 REGULATION OF GENE EXPRESSION EPIGENETIC 30 229 6.624e-15 7.903e-13
40 MITOTIC CELL CYCLE CHECKPOINT 24 139 6.836e-15 7.952e-13
41 CELL DIVISION 42 460 1.111e-14 1.261e-12
42 MITOTIC NUCLEAR DIVISION 37 361 1.272e-14 1.409e-12
43 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 47 573 1.548e-14 1.659e-12
44 REGULATION OF DNA BINDING 20 93 1.569e-14 1.659e-12
45 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 24 146 2.142e-14 2.215e-12
46 CHROMATIN ASSEMBLY OR DISASSEMBLY 26 177 2.789e-14 2.822e-12
47 ORGANELLE FISSION 43 496 3.249e-14 3.217e-12
48 PROTEIN DNA COMPLEX SUBUNIT ORGANIZATION 29 229 4.62e-14 4.478e-12
49 DNA REPAIR 42 480 4.797e-14 4.555e-12
50 REGULATION OF CHROMATIN ORGANIZATION 24 152 5.409e-14 5.034e-12
51 INTERSPECIES INTERACTION BETWEEN ORGANISMS 49 662 2.072e-13 1.854e-11
52 SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM 49 662 2.072e-13 1.854e-11
53 POSITIVE REGULATION OF CELL PROLIFERATION 55 814 2.621e-13 2.301e-11
54 REGULATION OF CELL CYCLE ARREST 20 108 3.178e-13 2.738e-11
55 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 67 1152 6.031e-13 5.102e-11
56 REGULATION OF CELL DEATH 78 1472 7.106e-13 5.904e-11
57 RESPONSE TO ENDOGENOUS STIMULUS 77 1450 9.217e-13 7.524e-11
58 NEGATIVE REGULATION OF BINDING 21 131 1.538e-12 1.234e-10
59 REGULATION OF DNA REPLICATION 23 161 1.601e-12 1.262e-10
60 NEGATIVE REGULATION OF MOLECULAR FUNCTION 63 1079 2.755e-12 2.137e-10
61 POSITIVE REGULATION OF CHROMOSOME ORGANIZATION 22 150 2.863e-12 2.184e-10
62 CELLULAR RESPONSE TO LIPID 38 457 3.891e-12 2.92e-10
63 POSITIVE REGULATION OF CELL CYCLE ARREST 17 85 5.255e-12 3.881e-10
64 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 88 1848 6.69e-12 4.864e-10
65 MITOTIC DNA INTEGRITY CHECKPOINT 18 100 8.148e-12 5.832e-10
66 REGULATION OF PROTEIN ACETYLATION 15 64 8.31e-12 5.859e-10
67 RESPONSE TO ORGANIC CYCLIC COMPOUND 56 917 9.106e-12 6.312e-10
68 RESPONSE TO ALCOHOL 33 362 9.224e-12 6.312e-10
69 RESPONSE TO STEROID HORMONE 39 497 1.186e-11 7.995e-10
70 DNA PACKAGING 24 194 1.225e-11 8.145e-10
71 REGULATION OF NUCLEAR DIVISION 22 163 1.561e-11 1.023e-09
72 REGULATION OF CELL DIVISION 28 272 2.092e-11 1.352e-09
73 PEPTIDYL LYSINE MODIFICATION 30 312 2.22e-11 1.415e-09
74 REGULATION OF PROTEIN BINDING 22 168 2.867e-11 1.803e-09
75 REGULATION OF TRANSFERASE ACTIVITY 56 946 3.056e-11 1.896e-09
76 SIGNAL TRANSDUCTION IN RESPONSE TO DNA DAMAGE 17 96 4.091e-11 2.505e-09
77 CELL CYCLE G1 S PHASE TRANSITION 18 111 5.044e-11 3.009e-09
78 G1 S TRANSITION OF MITOTIC CELL CYCLE 18 111 5.044e-11 3.009e-09
79 DNA REPLICATION 24 208 5.424e-11 3.195e-09
80 NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 17 98 5.76e-11 3.35e-09
81 G1 DNA DAMAGE CHECKPOINT 15 73 6.301e-11 3.619e-09
82 REGULATION OF CELL DIFFERENTIATION 74 1492 7.006e-11 3.976e-09
83 RESPONSE TO LIPID 53 888 8.087e-11 4.533e-09
84 RESPONSE TO HORMONE 53 893 9.928e-11 5.499e-09
85 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 20 147 1.142e-10 6.254e-09
86 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 57 1008 1.177e-10 6.368e-09
87 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 24 218 1.455e-10 7.78e-09
88 REGULATION OF PROTEIN MODIFICATION PROCESS 80 1710 1.767e-10 9.343e-09
89 RESPONSE TO ABIOTIC STIMULUS 57 1024 2.144e-10 1.121e-08
90 REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 11 36 2.288e-10 1.183e-08
91 NEGATIVE REGULATION OF ORGANELLE ORGANIZATION 32 387 2.393e-10 1.224e-08
92 AGING 26 264 2.931e-10 1.482e-08
93 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 44 684 3.663e-10 1.833e-08
94 NEGATIVE REGULATION OF CELL DEATH 51 872 3.867e-10 1.914e-08
95 NEGATIVE REGULATION OF CHROMOSOME ORGANIZATION 16 96 3.95e-10 1.935e-08
96 GLAND DEVELOPMENT 32 395 4.016e-10 1.946e-08
97 GENE SILENCING 23 212 4.735e-10 2.271e-08
98 SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR 18 127 4.97e-10 2.36e-08
99 POSITIVE REGULATION OF CHROMATIN MODIFICATION 15 85 6.095e-10 2.865e-08
100 RESPONSE TO OXYGEN CONTAINING COMPOUND 68 1381 6.404e-10 2.98e-08
101 PROTEIN LOCALIZATION TO ORGANELLE 38 556 1.173e-09 5.405e-08
102 POSITIVE REGULATION OF DNA METABOLIC PROCESS 21 185 1.188e-09 5.421e-08
103 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 34 465 1.646e-09 7.436e-08
104 CELL CYCLE G2 M PHASE TRANSITION 18 138 1.965e-09 8.79e-08
105 NEGATIVE REGULATION OF PROTEIN BINDING 14 79 2.159e-09 9.566e-08
106 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 67 1395 2.419e-09 1.062e-07
107 CELL AGING 13 67 2.541e-09 1.105e-07
108 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 70 1492 2.673e-09 1.152e-07
109 DNA GEOMETRIC CHANGE 14 81 3.037e-09 1.296e-07
110 POSITIVE REGULATION OF BINDING 17 127 3.704e-09 1.567e-07
111 NEGATIVE REGULATION OF GENE EXPRESSION EPIGENETIC 16 112 4.089e-09 1.714e-07
112 RESPONSE TO ESTRADIOL 18 146 4.911e-09 2.04e-07
113 POSITIVE REGULATION OF DNA REPLICATION 14 86 6.826e-09 2.811e-07
114 EMBRYO DEVELOPMENT 49 894 7.381e-09 3.013e-07
115 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 57 1142 1.157e-08 4.683e-07
116 RESPONSE TO DRUG 31 431 1.296e-08 5.198e-07
117 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 45 799 1.417e-08 5.636e-07
118 PROTEIN PHOSPHORYLATION 50 944 1.551e-08 6.116e-07
119 POSITIVE REGULATION OF DNA BINDING 10 42 2.23e-08 8.718e-07
120 RESPONSE TO ESTROGEN 21 218 2.274e-08 8.819e-07
121 DNA TEMPLATED TRANSCRIPTION INITIATION 20 202 3.107e-08 1.195e-06
122 PROTEIN ACETYLATION 16 129 3.232e-08 1.227e-06
123 CELL DEVELOPMENT 65 1426 3.244e-08 1.227e-06
124 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 54 1087 3.428e-08 1.286e-06
125 MACROMOLECULAR COMPLEX ASSEMBLY 64 1398 3.582e-08 1.333e-06
126 NUCLEOSOME DISASSEMBLY 7 17 4.326e-08 1.56e-06
127 PROTEIN DNA COMPLEX DISASSEMBLY 7 17 4.326e-08 1.56e-06
128 IMMUNE SYSTEM DEVELOPMENT 36 582 4.287e-08 1.56e-06
129 CHROMATIN DISASSEMBLY 7 17 4.326e-08 1.56e-06
130 REGULATION OF CELLULAR RESPONSE TO STRESS 40 691 4.54e-08 1.625e-06
131 CELL PROLIFERATION 39 672 6.306e-08 2.223e-06
132 TRANSCRIPTION INITIATION FROM RNA POLYMERASE II PROMOTER 17 153 6.282e-08 2.223e-06
133 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 27 365 6.472e-08 2.264e-06
134 POSITIVE REGULATION OF PROTEIN ACETYLATION 9 36 7.213e-08 2.505e-06
135 POSITIVE REGULATION OF MOLECULAR FUNCTION 75 1791 8.319e-08 2.867e-06
136 DNA RECOMBINATION 20 215 8.797e-08 3.01e-06
137 REGULATION OF TRANSCRIPTION INVOLVED IN G1 S TRANSITION OF MITOTIC CELL CYCLE 8 27 9.098e-08 3.09e-06
138 POSITIVE REGULATION OF MITOTIC CELL CYCLE 15 123 1.093e-07 3.659e-06
139 ENDOCRINE SYSTEM DEVELOPMENT 15 123 1.093e-07 3.659e-06
140 POSITIVE REGULATION OF CELL DEATH 36 605 1.125e-07 3.738e-06
141 RESPONSE TO GROWTH FACTOR 31 475 1.182e-07 3.901e-06
142 REGULATION OF KINASE ACTIVITY 42 776 1.327e-07 4.348e-06
143 PHOSPHORYLATION 57 1228 1.393e-07 4.534e-06
144 MRNA METABOLIC PROCESS 36 611 1.433e-07 4.631e-06
145 REGULATION OF SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR 17 162 1.456e-07 4.671e-06
146 POSITIVE REGULATION OF GENE EXPRESSION EPIGENETIC 12 78 1.571e-07 5.007e-06
147 IN UTERO EMBRYONIC DEVELOPMENT 24 311 1.616e-07 5.115e-06
148 DNA REPLICATION INITIATION 8 29 1.691e-07 5.317e-06
149 CENTRAL NERVOUS SYSTEM DEVELOPMENT 45 872 1.805e-07 5.636e-06
150 REGULATION OF HISTONE PHOSPHORYLATION 6 13 1.835e-07 5.692e-06
151 CHROMATIN SILENCING 13 95 1.978e-07 6.096e-06
152 SOMATIC STEM CELL POPULATION MAINTENANCE 11 66 2.234e-07 6.838e-06
153 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 70 1672 2.454e-07 7.441e-06
154 POSITIVE REGULATION OF CELL DIFFERENTIATION 43 823 2.463e-07 7.441e-06
155 DNA TEMPLATED TRANSCRIPTION ELONGATION 13 97 2.537e-07 7.617e-06
156 MACROMOLECULE DEACYLATION 11 67 2.619e-07 7.813e-06
157 MAINTENANCE OF CELL NUMBER 15 132 2.794e-07 8.28e-06
158 CELLULAR RESPONSE TO ALCOHOL 14 115 2.965e-07 8.732e-06
159 POSITIVE REGULATION OF CELL CYCLE PHASE TRANSITION 11 68 3.063e-07 8.963e-06
160 DNA DEPENDENT DNA REPLICATION 13 99 3.234e-07 9.379e-06
161 REGULATION OF MUSCLE CELL DIFFERENTIATION 16 152 3.245e-07 9.379e-06
162 CELLULAR RESPONSE TO HORMONE STIMULUS 33 552 3.48e-07 9.996e-06
163 POSTTRANSCRIPTIONAL REGULATION OF GENE EXPRESSION 29 448 3.614e-07 1.032e-05
164 PROTEIN COMPLEX SUBUNIT ORGANIZATION 65 1527 3.943e-07 1.119e-05
165 EPITHELIAL TO MESENCHYMAL TRANSITION 10 56 4.077e-07 1.15e-05
166 REGULATION OF RESPONSE TO STRESS 63 1468 4.616e-07 1.294e-05
167 INTRACELLULAR SIGNAL TRANSDUCTION 66 1572 5.176e-07 1.442e-05
168 PROTEIN LOCALIZATION TO CHROMOSOME 9 45 5.678e-07 1.573e-05
169 PROTEIN ACYLATION 16 159 6e-07 1.652e-05
170 ODONTOGENESIS 13 105 6.462e-07 1.769e-05
171 REGULATION OF CELL CYCLE G2 M PHASE TRANSITION 10 59 6.775e-07 1.84e-05
172 NEGATIVE REGULATION OF DNA BINDING 9 46 6.921e-07 1.84e-05
173 RESPONSE TO EXTERNAL STIMULUS 73 1821 6.862e-07 1.84e-05
174 HISTONE H3 ACETYLATION 9 46 6.921e-07 1.84e-05
175 REGULATION OF PHOSPHORUS METABOLIC PROCESS 67 1618 6.858e-07 1.84e-05
176 ATP DEPENDENT CHROMATIN REMODELING 11 74 7.401e-07 1.957e-05
177 RESPONSE TO RADIATION 27 413 7.597e-07 1.997e-05
178 SENSORY ORGAN DEVELOPMENT 30 493 8.334e-07 2.179e-05
179 HISTONE PHOSPHORYLATION 7 25 9.154e-07 2.38e-05
180 REGULATION OF VIRAL TRANSCRIPTION 10 61 9.343e-07 2.415e-05
181 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 29 470 9.635e-07 2.477e-05
182 REGULATION OF HOMEOSTATIC PROCESS 28 447 1.106e-06 2.828e-05
183 ORGAN MORPHOGENESIS 42 841 1.117e-06 2.84e-05
184 PEPTIDYL SERINE MODIFICATION 15 148 1.23e-06 3.111e-05
185 RNA CAPPING 8 37 1.3e-06 3.252e-05
186 X7 METHYLGUANOSINE RNA CAPPING 8 37 1.3e-06 3.252e-05
187 STEM CELL DIFFERENTIATION 17 190 1.407e-06 3.502e-05
188 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 34 616 1.417e-06 3.508e-05
189 REGULATION OF CATABOLIC PROCESS 38 731 1.44e-06 3.544e-05
190 REGULATION OF TELOMERE MAINTENANCE VIA TELOMERE LENGTHENING 9 50 1.454e-06 3.561e-05
191 NUCLEOTIDE EXCISION REPAIR 13 113 1.511e-06 3.681e-05
192 MESENCHYMAL CELL DIFFERENTIATION 14 134 1.934e-06 4.687e-05
193 POSITIVE REGULATION OF VIRAL TRANSCRIPTION 8 39 1.992e-06 4.752e-05
194 CELLULAR RESPONSE TO UV 10 66 1.978e-06 4.752e-05
195 BASE EXCISION REPAIR 8 39 1.992e-06 4.752e-05
196 TRANSCRIPTION ELONGATION FROM RNA POLYMERASE II PROMOTER 11 82 2.111e-06 5.012e-05
197 CELLULAR RESPONSE TO ABIOTIC STIMULUS 20 263 2.189e-06 5.17e-05
198 NEGATIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 14 136 2.31e-06 5.428e-05
199 ESTABLISHMENT OF PROTEIN LOCALIZATION TO ORGANELLE 24 361 2.349e-06 5.491e-05
200 ORGAN REGENERATION 11 83 2.385e-06 5.55e-05
201 CELLULAR RESPONSE TO RADIATION 14 137 2.521e-06 5.836e-05
202 LEUKOCYTE DIFFERENTIATION 21 292 2.973e-06 6.847e-05
203 MITOTIC SPINDLE ORGANIZATION 10 69 3.003e-06 6.883e-05
204 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 66 1656 3.121e-06 7.119e-05
205 NEGATIVE REGULATION OF DNA REPLICATION 9 55 3.342e-06 7.585e-05
206 PROTEIN COMPLEX BIOGENESIS 50 1132 3.615e-06 8.114e-05
207 MYELOID DENDRITIC CELL DIFFERENTIATION 6 20 3.627e-06 8.114e-05
208 PROTEIN COMPLEX ASSEMBLY 50 1132 3.615e-06 8.114e-05
209 REGULATION OF MESENCHYMAL CELL APOPTOTIC PROCESS 5 12 3.836e-06 8.54e-05
210 REGULATION OF HISTONE METHYLATION 9 56 3.904e-06 8.608e-05
211 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 50 1135 3.891e-06 8.608e-05
212 CELLULAR RESPONSE TO OXYGEN LEVELS 14 143 4.19e-06 9.169e-05
213 TUBE MORPHOGENESIS 22 323 4.197e-06 9.169e-05
214 REGULATION OF STEM CELL PROLIFERATION 11 88 4.278e-06 9.302e-05
215 REGULATION OF CYTOKINE PRODUCTION 31 563 4.381e-06 9.438e-05
216 NEUROGENESIS 58 1402 4.366e-06 9.438e-05
217 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 23 351 4.845e-06 0.0001039
218 RESPONSE TO UV 13 126 5.164e-06 0.0001098
219 LYMPHOCYTE DIFFERENTIATION 17 209 5.166e-06 0.0001098
220 CELL ACTIVATION 31 568 5.237e-06 0.0001108
221 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 29 513 5.417e-06 0.0001141
222 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 7 32 5.597e-06 0.0001173
223 CELLULAR RESPONSE TO LIGHT STIMULUS 11 91 5.956e-06 0.0001243
224 PROTEIN LOCALIZATION TO CHROMATIN 5 13 6.119e-06 0.0001271
225 ODONTOGENESIS OF DENTIN CONTAINING TOOTH 10 75 6.495e-06 0.0001343
226 POSITIVE REGULATION OF VIRAL PROCESS 11 92 6.631e-06 0.0001365
227 ENDOCARDIAL CUSHION MORPHOGENESIS 6 22 6.721e-06 0.0001378
228 NEGATIVE REGULATION OF DNA METABOLIC PROCESS 12 111 7.329e-06 0.0001496
229 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 13 131 7.938e-06 0.0001613
230 CELLULAR MACROMOLECULAR COMPLEX ASSEMBLY 36 727 8.115e-06 0.0001642
231 ANAPHASE PROMOTING COMPLEX DEPENDENT CATABOLIC PROCESS 10 77 8.259e-06 0.0001664
232 REGULATION OF APOPTOTIC SIGNALING PATHWAY 23 363 8.407e-06 0.0001686
233 INTRINSIC APOPTOTIC SIGNALING PATHWAY 14 152 8.538e-06 0.0001705
234 POSITIVE REGULATION OF CELL DIVISION 13 132 8.629e-06 0.0001709
235 NEGATIVE REGULATION OF MITOTIC NUCLEAR DIVISION 7 34 8.606e-06 0.0001709
236 THYMUS DEVELOPMENT 8 47 8.702e-06 0.0001716
237 POSITIVE REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 5 14 9.343e-06 0.0001834
238 NEGATIVE REGULATION OF CELL PROLIFERATION 33 643 9.423e-06 0.0001842
239 HOMEOSTASIS OF NUMBER OF CELLS 15 175 9.848e-06 0.0001917
240 REGULATION OF PROTEIN CATABOLIC PROCESS 24 393 9.953e-06 0.000193
241 MYELOID LEUKOCYTE DIFFERENTIATION 11 96 1.004e-05 0.0001939
242 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 32 616 1.011e-05 0.0001944
243 POSITIVE REGULATION OF RESPONSE TO STIMULUS 72 1929 1.052e-05 0.0002012
244 SISTER CHROMATID SEGREGATION 15 176 1.055e-05 0.0002012
245 PROTEIN LOCALIZATION TO NUCLEUS 14 156 1.151e-05 0.0002186
246 HEAD DEVELOPMENT 35 709 1.161e-05 0.0002197
247 TISSUE DEVELOPMENT 60 1518 1.195e-05 0.000225
248 POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 7 36 1.285e-05 0.000241
249 CHROMOSOME SEGREGATION 19 272 1.326e-05 0.0002478
250 REGULATION OF CELL DEVELOPMENT 39 836 1.343e-05 0.00025
251 CELLULAR COMPONENT MORPHOGENESIS 41 900 1.403e-05 0.000258
252 RESPONSE TO GAMMA RADIATION 8 50 1.401e-05 0.000258
253 MULTI ORGANISM METABOLIC PROCESS 13 138 1.4e-05 0.000258
254 SPINDLE CHECKPOINT 6 25 1.507e-05 0.0002761
255 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 55 1360 1.515e-05 0.0002764
256 MRNA PROCESSING 25 432 1.631e-05 0.000293
257 CELL DEATH 44 1001 1.623e-05 0.000293
258 EYE DEVELOPMENT 21 326 1.615e-05 0.000293
259 NUCLEAR CHROMOSOME SEGREGATION 17 228 1.628e-05 0.000293
260 REPRODUCTION 53 1297 1.653e-05 0.0002958
261 REGULATION OF TELOMERE MAINTENANCE 9 67 1.772e-05 0.0003148
262 REGULATION OF SISTER CHROMATID SEGREGATION 9 67 1.772e-05 0.0003148
263 HISTONE METHYLATION 10 84 1.808e-05 0.0003187
264 FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 10 84 1.808e-05 0.0003187
265 REGULATION OF DOUBLE STRAND BREAK REPAIR 7 38 1.869e-05 0.0003269
266 MESENCHYME MORPHOGENESIS 7 38 1.869e-05 0.0003269
267 MYELOID DENDRITIC CELL ACTIVATION 6 26 1.922e-05 0.000335
268 EPITHELIUM DEVELOPMENT 42 945 1.97e-05 0.0003421
269 REGULATION OF CHROMOSOME SEGREGATION 10 85 2.009e-05 0.0003475
270 FOREBRAIN DEVELOPMENT 22 357 2.025e-05 0.000349
271 EPITHELIAL CELL DIFFERENTIATION 27 495 2.155e-05 0.00037
272 RESPONSE TO IONIZING RADIATION 13 145 2.38e-05 0.0004072
273 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 27 498 2.396e-05 0.0004083
274 REGULATION OF HISTONE H3 K4 METHYLATION 6 27 2.425e-05 0.0004118
275 MYELOID CELL DIFFERENTIATION 15 189 2.463e-05 0.0004167
276 MORPHOGENESIS OF A BRANCHING STRUCTURE 14 167 2.49e-05 0.0004198
277 RESPONSE TO OXYGEN LEVELS 20 311 2.625e-05 0.0004409
278 MACROMOLECULE CATABOLIC PROCESS 41 926 2.708e-05 0.0004532
279 NEGATIVE REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 5 17 2.732e-05 0.0004556
280 CARTILAGE DEVELOPMENT 13 147 2.753e-05 0.0004575
281 RESPONSE TO NUTRIENT 15 191 2.786e-05 0.0004614
282 APPENDAGE DEVELOPMENT 14 169 2.844e-05 0.0004676
283 LIMB DEVELOPMENT 14 169 2.844e-05 0.0004676
284 TISSUE MORPHOGENESIS 28 533 2.983e-05 0.0004887
285 MAMMARY GLAND DUCT MORPHOGENESIS 6 28 3.028e-05 0.0004944
286 CELLULAR RESPONSE TO EXTERNAL STIMULUS 18 264 3.076e-05 0.0005005
287 POSITIVE REGULATION OF HOMEOSTATIC PROCESS 16 216 3.116e-05 0.0005051
288 NEGATIVE REGULATION OF PHOSPHORYLATION 24 422 3.181e-05 0.0005139
289 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 14 171 3.242e-05 0.0005219
290 TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR 9 73 3.575e-05 0.0005716
291 RNA SPLICING VIA TRANSESTERIFICATION REACTIONS 18 267 3.57e-05 0.0005716
292 EMBRYONIC MORPHOGENESIS 28 539 3.636e-05 0.0005793
293 REGULATION OF MICROTUBULE BASED PROCESS 17 243 3.681e-05 0.0005845
294 POSITIVE REGULATION OF CELL CYCLE G2 M PHASE TRANSITION 5 18 3.713e-05 0.0005876
295 POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 6 29 3.746e-05 0.0005909
296 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 33 689 3.773e-05 0.0005911
297 POSITIVE REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 15 196 3.764e-05 0.0005911
298 REGULATION OF PROTEIN STABILITY 16 221 4.112e-05 0.0006421
299 REGULATION OF GROWTH 31 633 4.295e-05 0.0006685
300 REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 7 43 4.332e-05 0.0006705
301 PROTEASOMAL PROTEIN CATABOLIC PROCESS 18 271 4.337e-05 0.0006705
302 NEURON PROJECTION DEVELOPMENT 28 545 4.415e-05 0.0006802
303 RHYTHMIC PROCESS 19 298 4.672e-05 0.0007174
304 REGULATION OF PROTEIN LOCALIZATION 41 950 4.821e-05 0.000738
305 REGULATION OF INTRACELLULAR STEROID HORMONE RECEPTOR SIGNALING PATHWAY 8 59 4.853e-05 0.0007403
306 NEGATIVE REGULATION OF CELL DIFFERENTIATION 30 609 5.13e-05 0.0007801
307 REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 21 354 5.41e-05 0.0008199
308 NEGATIVE REGULATION OF CELL DIVISION 8 60 5.491e-05 0.0008242
309 CHONDROCYTE DIFFERENTIATION 8 60 5.491e-05 0.0008242
310 POSITIVE REGULATION OF MULTI ORGANISM PROCESS 13 157 5.486e-05 0.0008242
311 REGULATION OF CELLULAR PROTEIN LOCALIZATION 28 552 5.513e-05 0.0008248
312 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 41 957 5.675e-05 0.0008455
313 RESPONSE TO ETHANOL 12 136 5.7e-05 0.0008455
314 GROWTH 23 410 5.715e-05 0.0008455
315 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 37 829 5.724e-05 0.0008455
316 NEGATIVE REGULATION OF CHROMATIN MODIFICATION 7 45 5.87e-05 0.0008644
317 RESPONSE TO FIBROBLAST GROWTH FACTOR 11 116 5.997e-05 0.0008803
318 REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS 14 181 6.051e-05 0.0008854
319 NEGATIVE REGULATION OF CELL COMMUNICATION 48 1192 6.112e-05 0.0008915
320 POSITIVE REGULATION OF STEM CELL PROLIFERATION 8 61 6.197e-05 0.0009011
321 RESPONSE TO EXTRACELLULAR STIMULUS 24 441 6.375e-05 0.0009212
322 REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 10 97 6.36e-05 0.0009212
323 PROTEIN METHYLATION 11 117 6.489e-05 0.000929
324 MAMMARY GLAND DEVELOPMENT 11 117 6.489e-05 0.000929
325 PROTEIN ALKYLATION 11 117 6.489e-05 0.000929
326 RNA PROCESSING 37 835 6.643e-05 0.0009481
327 ENDOCARDIAL CUSHION DEVELOPMENT 6 32 6.752e-05 0.0009578
328 BONE MORPHOGENESIS 9 79 6.733e-05 0.0009578
329 NEGATIVE REGULATION OF NUCLEAR DIVISION 7 46 6.792e-05 0.0009605
330 DEVELOPMENTAL GROWTH 20 333 6.842e-05 0.0009647
331 REGULATION OF PROTEOLYSIS 33 711 6.927e-05 0.0009737
332 REGENERATION 13 161 7.111e-05 0.0009966
333 REGULATION OF CYTOSKELETON ORGANIZATION 26 502 7.227e-05 0.001005
334 EPITHELIAL TO MESENCHYMAL TRANSITION INVOLVED IN ENDOCARDIAL CUSHION FORMATION 4 11 7.235e-05 0.001005
335 VIRAL LATENCY 4 11 7.235e-05 0.001005
336 MEMBRANE DISASSEMBLY 7 47 7.828e-05 0.001081
337 NUCLEAR ENVELOPE DISASSEMBLY 7 47 7.828e-05 0.001081
338 DENDRITIC CELL DIFFERENTIATION 6 33 8.098e-05 0.001105
339 CELLULAR SENESCENCE 6 33 8.098e-05 0.001105
340 POSITIVE REGULATION OF TELOMERE MAINTENANCE VIA TELOMERE LENGTHENING 6 33 8.098e-05 0.001105
341 G2 DNA DAMAGE CHECKPOINT 6 33 8.098e-05 0.001105
342 REGULATION OF FIBROBLAST PROLIFERATION 9 81 8.205e-05 0.001116
343 HEMOSTASIS 19 311 8.263e-05 0.001121
344 REGULATION OF EPITHELIAL CELL PROLIFERATION 18 285 8.305e-05 0.001123
345 PLATELET ACTIVATION 12 142 8.668e-05 0.001169
346 NEGATIVE REGULATION OF CYTOKINE PRODUCTION 15 211 8.733e-05 0.001174
347 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 7 48 8.99e-05 0.001201
348 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 16 236 8.985e-05 0.001201
349 RNA SPLICING 21 367 9.032e-05 0.001201
350 SNRNA METABOLIC PROCESS 9 82 9.037e-05 0.001201
351 POSITIVE REGULATION OF CYTOKINE PRODUCTION 21 370 0.0001012 0.001342
352 MESENCHYME DEVELOPMENT 14 190 0.000102 0.001349
353 SKELETAL SYSTEM DEVELOPMENT 24 455 0.0001032 0.001357
354 POSITIVE REGULATION OF MITOCHONDRION ORGANIZATION 13 167 0.0001033 0.001357
355 REGULATION OF MUSCLE TISSUE DEVELOPMENT 10 103 0.0001059 0.001377
356 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 10 103 0.0001059 0.001377
357 REGULATION OF MUSCLE ORGAN DEVELOPMENT 10 103 0.0001059 0.001377
358 HISTONE H3 DEACETYLATION 5 22 0.000106 0.001377
359 TRANSCRIPTION FROM RNA POLYMERASE I PROMOTER 6 35 0.0001143 0.001481
360 CARDIAC CHAMBER MORPHOGENESIS 10 104 0.0001149 0.001485
361 HISTONE H4 ACETYLATION 7 50 0.0001173 0.001513
362 NEURON PROJECTION MORPHOGENESIS 22 402 0.000118 0.001517
363 REGULATION OF STRIATED MUSCLE CELL DIFFERENTIATION 9 85 0.0001197 0.001534
364 REGULATION OF ORGAN MORPHOGENESIS 16 242 0.0001204 0.001539
365 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 15 218 0.0001257 0.001603
366 CONNECTIVE TISSUE DEVELOPMENT 14 194 0.0001273 0.001618
367 REGULATION OF PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 12 148 0.0001288 0.001629
368 RESPONSE TO TRANSITION METAL NANOPARTICLE 12 148 0.0001288 0.001629
369 POSITIVE REGULATION OF DNA TEMPLATED TRANSCRIPTION ELONGATION 5 23 0.0001329 0.001676
370 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 69 1977 0.0001339 0.001684
371 NEGATIVE REGULATION OF HISTONE MODIFICATION 6 36 0.0001345 0.001687
372 TUBE DEVELOPMENT 27 552 0.0001362 0.001699
373 EMBRYONIC ORGAN DEVELOPMENT 22 406 0.000136 0.001699
374 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 27 554 0.0001445 0.001797
375 PROTEIN LOCALIZATION TO CHROMOSOME CENTROMERIC REGION 4 13 0.0001513 0.001872
376 EYELID DEVELOPMENT IN CAMERA TYPE EYE 4 13 0.0001513 0.001872
377 NCRNA TRANSCRIPTION 9 88 0.0001566 0.001932
378 POSITIVE REGULATION OF TYPE I INTERFERON PRODUCTION 8 70 0.0001667 0.002042
379 NEURON DIFFERENTIATION 37 874 0.0001667 0.002042
380 REGULATION OF MEMBRANE PERMEABILITY 8 70 0.0001667 0.002042
381 REGULATION OF LIGASE ACTIVITY 11 130 0.0001677 0.002048
382 POSITIVE REGULATION OF FIBROBLAST PROLIFERATION 7 53 0.0001709 0.002077
383 MAMMARY GLAND EPITHELIUM DEVELOPMENT 7 53 0.0001709 0.002077
384 RESPONSE TO CORTICOSTEROID 13 176 0.0001748 0.002118
385 POSITIVE REGULATION OF LIGASE ACTIVITY 10 110 0.0001833 0.002209
386 OSSIFICATION 16 251 0.0001833 0.002209
387 INTRACELLULAR STEROID HORMONE RECEPTOR SIGNALING PATHWAY 8 71 0.0001842 0.002215
388 RESPONSE TO WOUNDING 27 563 0.0001874 0.002247
389 GAMETE GENERATION 28 595 0.0001954 0.002326
390 REGULATION OF MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION 13 178 0.0001955 0.002326
391 REGULATION OF OSSIFICATION 13 178 0.0001955 0.002326
392 POSITIVE REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 10 111 0.0001975 0.002332
393 SISTER CHROMATID COHESION 10 111 0.0001975 0.002332
394 REGULATION OF TYPE I INTERFERON PRODUCTION 10 111 0.0001975 0.002332
395 TROPHECTODERMAL CELL DIFFERENTIATION 4 14 0.000208 0.002438
396 PEPTIDYL ARGININE METHYLATION 4 14 0.000208 0.002438
397 REGULATION OF HISTONE H3 K9 ACETYLATION 4 14 0.000208 0.002438
398 BONE DEVELOPMENT 12 156 0.0002114 0.002471
399 REGULATION OF CENTROSOME CYCLE 6 39 0.0002129 0.002471
400 EAR MORPHOGENESIS 10 112 0.0002126 0.002471
401 CELLULAR RESPONSE TO NUTRIENT 6 39 0.0002129 0.002471
402 NEGATIVE REGULATION OF MUSCLE CELL DIFFERENTIATION 7 55 0.0002166 0.002506
403 POSITIVE REGULATION OF PROTEOLYSIS 20 363 0.0002182 0.00252
404 MITOCHONDRIAL MEMBRANE ORGANIZATION 9 92 0.00022 0.002534
405 REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 8 73 0.0002239 0.002572
406 MACROMOLECULE METHYLATION 14 205 0.0002265 0.002595
407 REGULATION OF STEM CELL DIFFERENTIATION 10 113 0.0002286 0.002614
408 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 26 541 0.0002377 0.002704
409 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 26 541 0.0002377 0.002704
410 RESPONSE TO KETONE 13 182 0.0002432 0.002753
411 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 7 56 0.0002428 0.002753
412 MAMMARY GLAND MORPHOGENESIS 6 40 0.0002458 0.00277
413 FEMALE MEIOTIC DIVISION 5 26 0.0002459 0.00277
414 RESPONSE TO NITROGEN COMPOUND 36 859 0.0002477 0.002784
415 SEXUAL REPRODUCTION 32 730 0.0002506 0.00281
416 REGULATION OF DNA BIOSYNTHETIC PROCESS 9 94 0.000259 0.002897
417 REGULATION OF DNA REPAIR 8 75 0.0002703 0.003016
418 REGULATION OF TELOMERASE RNA LOCALIZATION TO CAJAL BODY 4 15 0.0002787 0.003073
419 MALE GAMETE GENERATION 24 486 0.0002763 0.003073
420 ENDOCARDIAL CUSHION FORMATION 4 15 0.0002787 0.003073
421 POSITIVE REGULATION OF TELOMERASE RNA LOCALIZATION TO CAJAL BODY 4 15 0.0002787 0.003073
422 HISTONE H2A ACETYLATION 4 15 0.0002787 0.003073
423 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 6 41 0.0002826 0.003079
424 MITOTIC SPINDLE ASSEMBLY 6 41 0.0002826 0.003079
425 LYMPHOCYTE ACTIVATION 19 342 0.0002809 0.003079
426 MICROTUBULE CYTOSKELETON ORGANIZATION INVOLVED IN MITOSIS 6 41 0.0002826 0.003079
427 CELLULAR RESPONSE TO ESTROGEN STIMULUS 6 41 0.0002826 0.003079
428 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 34 801 0.0002919 0.003173
429 MORPHOGENESIS OF AN EPITHELIUM 21 400 0.0002941 0.00319
430 POSITIVE REGULATION OF HEART GROWTH 5 27 0.0002963 0.003198
431 INFLAMMATORY RESPONSE TO ANTIGENIC STIMULUS 5 27 0.0002963 0.003198
432 REGULATION OF RNA STABILITY 11 139 0.0003012 0.003231
433 APOPTOTIC SIGNALING PATHWAY 17 289 0.0003014 0.003231
434 GENE SILENCING BY RNA 11 139 0.0003012 0.003231
435 CELLULAR RESPONSE TO CORTICOSTEROID STIMULUS 7 58 0.0003029 0.00324
436 MUSCLE CELL DIFFERENTIATION 15 237 0.000312 0.003329
437 VIRAL LIFE CYCLE 17 290 0.0003137 0.00334
438 HEART MORPHOGENESIS 14 212 0.0003195 0.003394
439 CYTOSKELETON ORGANIZATION 35 838 0.0003214 0.003406
440 PITUITARY GLAND DEVELOPMENT 6 42 0.0003235 0.003406
441 POSITIVE REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 6 42 0.0003235 0.003406
442 REGULATION OF HEART GROWTH 6 42 0.0003235 0.003406
443 GLAND MORPHOGENESIS 9 97 0.0003281 0.003447
444 PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 36 873 0.000336 0.003521
445 POSITIVE REGULATION OF DNA BIOSYNTHETIC PROCESS 7 59 0.0003371 0.003525
446 SENSORY ORGAN MORPHOGENESIS 15 239 0.0003412 0.003559
447 MICROTUBULE CYTOSKELETON ORGANIZATION 19 348 0.0003489 0.003632
448 NEGATIVE REGULATION OF CHROMOSOME SEGREGATION 5 28 0.0003541 0.003678
449 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 21 406 0.0003585 0.003715
450 REGULATION OF MAMMARY GLAND EPITHELIAL CELL PROLIFERATION 4 16 0.000365 0.003749
451 DNA LIGATION 4 16 0.000365 0.003749
452 CELL SURFACE RECEPTOR SIGNALING PATHWAY INVOLVED IN HEART DEVELOPMENT 4 16 0.000365 0.003749
453 V D J RECOMBINATION 4 16 0.000365 0.003749
454 REGULATION OF TELOMERASE ACTIVITY 6 43 0.000369 0.003782
455 HEART DEVELOPMENT 23 466 0.0003712 0.003796
456 REGULATION OF PROTEIN COMPLEX DISASSEMBLY 14 217 0.0004045 0.004127
457 CARDIAC CHAMBER DEVELOPMENT 11 144 0.0004081 0.004146
458 PROTEIN AUTOPHOSPHORYLATION 13 192 0.0004081 0.004146
459 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 39 983 0.0004101 0.004157
460 NEURON DEVELOPMENT 30 687 0.0004149 0.004188
461 EMBRYONIC DIGIT MORPHOGENESIS 7 61 0.0004149 0.004188
462 WOUND HEALING 23 470 0.0004183 0.004203
463 INTRACELLULAR RECEPTOR SIGNALING PATHWAY 12 168 0.0004177 0.004203
464 REGULATION OF DNA TEMPLATED TRANSCRIPTION ELONGATION 6 44 0.0004193 0.004204
465 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 10 122 0.0004247 0.00425
466 REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY 11 145 0.0004329 0.004323
467 RESPONSE TO BIOTIC STIMULUS 36 886 0.0004422 0.004406
468 NUCLEAR TRANSPORT 19 355 0.000446 0.004434
469 ANTERIOR POSTERIOR PATTERN SPECIFICATION 13 194 0.0004506 0.00447
470 T CELL DIFFERENTIATION 10 123 0.0004533 0.004487
471 CARDIAC VENTRICLE MORPHOGENESIS 7 62 0.0004588 0.004514
472 BLASTOCYST DEVELOPMENT 7 62 0.0004588 0.004514
473 POSITIVE REGULATION OF NUCLEAR DIVISION 7 62 0.0004588 0.004514
474 REGULATION OF CHROMATIN BINDING 4 17 0.0004689 0.004584
475 NEGATIVE REGULATION OF TELOMERE MAINTENANCE VIA TELOMERE LENGTHENING 4 17 0.0004689 0.004584
476 REGULATION OF STEM CELL POPULATION MAINTENANCE 4 17 0.0004689 0.004584
477 EAR DEVELOPMENT 13 195 0.0004732 0.004616
478 EXOCRINE SYSTEM DEVELOPMENT 6 45 0.0004747 0.004621
479 NEGATIVE REGULATION OF CYTOSKELETON ORGANIZATION 14 221 0.0004857 0.004718
480 REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 16 274 0.0004872 0.004723
481 BLASTOCYST FORMATION 5 30 0.0004949 0.004757
482 RESPONSE TO EPIDERMAL GROWTH FACTOR 5 30 0.0004949 0.004757
483 CELLULAR RESPONSE TO ESTRADIOL STIMULUS 5 30 0.0004949 0.004757
484 CELLULAR MACROMOLECULE LOCALIZATION 46 1234 0.0004931 0.004757
485 DIGESTIVE SYSTEM DEVELOPMENT 11 148 0.000515 0.004932
486 STEROID HORMONE MEDIATED SIGNALING PATHWAY 10 125 0.0005151 0.004932
487 PATTERN SPECIFICATION PROCESS 21 418 0.0005249 0.005015
488 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 19 360 0.000529 0.005044
489 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 27 602 0.0005339 0.005081
490 NEGATIVE REGULATION OF KINASE ACTIVITY 15 250 0.0005473 0.005197
491 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 10 126 0.0005486 0.005199
492 REGULATION OF CELLULAR LOCALIZATION 47 1277 0.0005639 0.005333
493 CHROMOSOME CONDENSATION 5 31 0.0005793 0.005456
494 RNA STABILIZATION 5 31 0.0005793 0.005456
495 POSITIVE REGULATION OF MUSCLE CELL DIFFERENTIATION 8 84 0.0005864 0.005513
496 OOCYTE MATURATION 4 18 0.0005923 0.005557
497 POSITIVE REGULATION OF TELOMERE MAINTENANCE 6 47 0.0006027 0.005642
498 POSITIVE REGULATION OF CELL COMMUNICATION 54 1532 0.0006102 0.005702
499 REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 16 280 0.0006161 0.005733
500 RESPONSE TO LIGHT STIMULUS 16 280 0.0006161 0.005733
501 CELL FATE COMMITMENT 14 227 0.0006333 0.005847
502 RNA CATABOLIC PROCESS 14 227 0.0006333 0.005847
503 CELLULAR COMPONENT DISASSEMBLY 24 515 0.0006327 0.005847
504 SKELETAL SYSTEM MORPHOGENESIS 13 201 0.0006298 0.005847
505 EPHRIN RECEPTOR SIGNALING PATHWAY 8 85 0.0006349 0.00585
506 POSITIVE REGULATION OF CATABOLIC PROCESS 20 395 0.0006422 0.005905
507 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 14 228 0.0006613 0.006069
508 METHYLATION 16 284 0.0007173 0.00657
509 SINGLE ORGANISM CELL ADHESION 22 459 0.00073 0.006661
510 CELLULAR RESPONSE TO GAMMA RADIATION 4 19 0.0007371 0.006661
511 REGULATION OF DOUBLE STRAND BREAK REPAIR VIA HOMOLOGOUS RECOMBINATION 4 19 0.0007371 0.006661
512 REGULATION OF CARDIAC MUSCLE CELL DIFFERENTIATION 4 19 0.0007371 0.006661
513 PEPTIDYL ARGININE MODIFICATION 4 19 0.0007371 0.006661
514 POSITIVE REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 4 19 0.0007371 0.006661
515 REGULATION OF DNA TEMPLATED TRANSCRIPTION IN RESPONSE TO STRESS 7 67 0.0007373 0.006661
516 ANATOMICAL STRUCTURE HOMEOSTASIS 16 285 0.0007448 0.006716
517 REGULATION OF SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM 13 205 0.0007569 0.006812
518 MICROTUBULE BASED PROCESS 24 522 0.0007634 0.006857
519 REGULATION OF HEMOPOIESIS 17 314 0.0007725 0.006926
520 MEIOSIS I 8 88 0.0008001 0.00716
521 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 31 750 0.0008308 0.007419
522 LYMPHOCYTE HOMEOSTASIS 6 50 0.000843 0.007514
523 REGULATION OF INTRACELLULAR TRANSPORT 27 621 0.0008513 0.007573
524 PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 10 134 0.0008867 0.007873
525 HORMONE MEDIATED SIGNALING PATHWAY 11 158 0.0008884 0.007874
526 T CELL HOMEOSTASIS 5 34 0.0008978 0.007927
527 ORGAN FORMATION 5 34 0.0008978 0.007927
528 REGULATION OF SMOOTH MUSCLE CELL DIFFERENTIATION 4 20 0.0009052 0.007947
529 BRANCHING INVOLVED IN MAMMARY GLAND DUCT MORPHOGENESIS 4 20 0.0009052 0.007947
530 INTRACELLULAR ESTROGEN RECEPTOR SIGNALING PATHWAY 4 20 0.0009052 0.007947
531 POSITIVE REGULATION OF PROTEIN CATABOLIC PROCESS 15 263 0.00092 0.008024
532 REGULATION OF MAP KINASE ACTIVITY 17 319 0.0009195 0.008024
533 CARDIOVASCULAR SYSTEM DEVELOPMENT 32 788 0.0009209 0.008024
534 CIRCULATORY SYSTEM DEVELOPMENT 32 788 0.0009209 0.008024
535 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 21 437 0.0009259 0.008052
536 SPINDLE ASSEMBLY 7 70 0.0009597 0.008331
537 NUCLEUS ORGANIZATION 10 136 0.0009936 0.00861
538 REGULATION OF PROTEIN OLIGOMERIZATION 5 35 0.001028 0.008883
539 MEIOTIC CELL CYCLE 12 186 0.001029 0.008883
540 POSITIVE REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY 6 52 0.00104 0.008963
541 CELL FATE SPECIFICATION 7 71 0.001044 0.008983
542 MRNA TRANSCRIPTION 4 21 0.001099 0.009379
543 COCHLEA MORPHOGENESIS 4 21 0.001099 0.009379
544 NEGATIVE REGULATION OF PROTEIN ACETYLATION 4 21 0.001099 0.009379
545 EPITHELIAL STRUCTURE MAINTENANCE 4 21 0.001099 0.009379
546 CELLULAR RESPONSE TO NITROGEN COMPOUND 23 505 0.001106 0.00943
547 CELL PART MORPHOGENESIS 27 633 0.001127 0.009591
548 REGULATION OF BODY FLUID LEVELS 23 506 0.001136 0.009625
549 PROTEIN SUMOYLATION 9 115 0.001135 0.009625
550 LEUKOCYTE ACTIVATION 20 414 0.001141 0.00965
551 POSITIVE REGULATION OF HEMOPOIESIS 11 163 0.001146 0.009661
552 CELLULAR RESPONSE TO BIOTIC STIMULUS 11 163 0.001146 0.009661
553 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 6 53 0.001151 0.009686
554 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 34 867 0.001166 0.00979
555 REGULATION OF ERYTHROCYTE DIFFERENTIATION 5 36 0.001173 0.00983
NumGOOverlapSizeP ValueAdj. P Value
1 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 105 1199 8.516e-35 7.911e-32
2 SEQUENCE SPECIFIC DNA BINDING 92 1037 1.005e-30 4.67e-28
3 CHROMATIN BINDING 59 435 3.275e-29 1.014e-26
4 DOUBLE STRANDED DNA BINDING 71 764 8.479e-25 1.969e-22
5 TRANSCRIPTION FACTOR BINDING 58 524 4.292e-24 7.975e-22
6 REGULATORY REGION NUCLEIC ACID BINDING 72 818 9.84e-24 1.523e-21
7 MACROMOLECULAR COMPLEX BINDING 96 1399 1.537e-23 2.04e-21
8 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 60 588 4.587e-23 5.327e-21
9 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 52 629 3.957e-16 4.084e-14
10 CORE PROMOTER BINDING 26 152 6.356e-16 5.905e-14
11 STRUCTURE SPECIFIC DNA BINDING 23 118 1.605e-15 1.356e-13
12 ENZYME BINDING 92 1737 3.761e-15 2.912e-13
13 CORE PROMOTER PROXIMAL REGION DNA BINDING 38 371 5.608e-15 4.007e-13
14 NUCLEOSOMAL DNA BINDING 13 30 2.548e-14 1.691e-12
15 CHROMATIN DNA BINDING 18 80 1.424e-13 8.821e-12
16 KINASE BINDING 46 606 4.907e-13 2.849e-11
17 TRANSCRIPTION COACTIVATOR ACTIVITY 31 296 1.082e-12 5.914e-11
18 NUCLEOSOME BINDING 13 45 1.144e-11 5.905e-10
19 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 31 328 1.591e-11 7.778e-10
20 ENHANCER BINDING 17 93 2.408e-11 1.119e-09
21 RNA BINDING 78 1598 4.192e-11 1.854e-09
22 CORE PROMOTER SEQUENCE SPECIFIC DNA BINDING 17 101 9.472e-11 4e-09
23 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 55 992 5.325e-10 2.151e-08
24 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 28 315 6.432e-10 2.49e-08
25 RNA POLYMERASE II CORE PROMOTER SEQUENCE SPECIFIC DNA BINDING 12 53 1.601e-09 5.875e-08
26 POLY A RNA BINDING 60 1170 1.644e-09 5.875e-08
27 ADENYL NUCLEOTIDE BINDING 70 1514 4.901e-09 1.686e-07
28 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 22 226 8.659e-09 2.873e-07
29 PROTEIN COMPLEX BINDING 50 935 1.14e-08 3.651e-07
30 IDENTICAL PROTEIN BINDING 59 1209 1.403e-08 4.344e-07
31 RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC DNA BINDING 12 65 1.896e-08 5.681e-07
32 PROTEIN DEACETYLASE ACTIVITY 10 43 2.848e-08 8.267e-07
33 PROTEIN DIMERIZATION ACTIVITY 56 1149 3.571e-08 1.005e-06
34 KINASE ACTIVITY 45 842 6.629e-08 1.811e-06
35 RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 14 104 8.286e-08 2.199e-06
36 RIBONUCLEOTIDE BINDING 77 1860 8.678e-08 2.239e-06
37 PROTEIN KINASE ACTIVITY 37 640 1.535e-07 3.855e-06
38 PROTEIN HETERODIMERIZATION ACTIVITY 30 468 2.789e-07 6.819e-06
39 DEACETYLASE ACTIVITY 10 55 3.416e-07 8.138e-06
40 HISTONE DEACETYLASE BINDING 13 105 6.462e-07 1.501e-05
41 PROTEIN SERINE THREONINE KINASE ACTIVITY 28 445 1.013e-06 2.294e-05
42 STEROID HORMONE RECEPTOR BINDING 11 81 1.865e-06 4.125e-05
43 DNA HELICASE ACTIVITY 9 53 2.423e-06 5.235e-05
44 HISTONE KINASE ACTIVITY 6 19 2.588e-06 5.464e-05
45 HORMONE RECEPTOR BINDING 15 168 5.995e-06 0.0001238
46 CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 7 34 8.606e-06 0.0001738
47 PROTEIN HOMODIMERIZATION ACTIVITY 35 722 1.704e-05 0.0003368
48 HYDROLASE ACTIVITY ACTING ON CARBON NITROGEN BUT NOT PEPTIDE BONDS IN LINEAR AMIDES 10 84 1.808e-05 0.00035
49 RNA POLYMERASE II REPRESSING TRANSCRIPTION FACTOR BINDING 6 27 2.425e-05 0.0004597
50 NAD DEPENDENT PROTEIN DEACETYLASE ACTIVITY 5 17 2.732e-05 0.0005075
51 BHLH TRANSCRIPTION FACTOR BINDING 6 28 3.028e-05 0.0005516
52 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC BINDING 10 90 3.325e-05 0.000594
53 REPRESSING TRANSCRIPTION FACTOR BINDING 8 57 3.76e-05 0.0006591
54 HELICASE ACTIVITY 13 153 4.194e-05 0.0007216
55 HISTONE METHYLTRANSFERASE ACTIVITY 8 58 4.277e-05 0.0007225
56 SINGLE STRANDED DNA BINDING 10 93 4.424e-05 0.0007339
57 PROTEIN METHYLTRANSFERASE ACTIVITY 9 82 9.037e-05 0.001473
58 TAU PROTEIN KINASE ACTIVITY 4 12 0.0001066 0.001679
59 HISTONE DEACETYLASE ACTIVITY H3 K14 SPECIFIC 4 12 0.0001066 0.001679
60 PEPTIDE N ACETYLTRANSFERASE ACTIVITY 8 67 0.0001221 0.001891
61 N ACETYLTRANSFERASE ACTIVITY 9 87 0.0001433 0.002183
62 MAP KINASE ACTIVITY 4 14 0.000208 0.003068
63 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 11 133 0.000205 0.003068
64 ANDROGEN RECEPTOR BINDING 6 39 0.0002129 0.003091
65 PROTEIN C TERMINUS BINDING 13 186 0.0003006 0.004296
66 UBIQUITIN LIKE PROTEIN LIGASE BINDING 16 264 0.0003236 0.004554
67 PROTEASOME BINDING 4 16 0.000365 0.005061
68 DNA DEPENDENT ATPASE ACTIVITY 8 79 0.0003867 0.005283
69 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 12 168 0.0004177 0.005486
70 UNFOLDED PROTEIN BINDING 9 100 0.0004118 0.005486
71 RNA POLYMERASE ACTIVITY 6 44 0.0004193 0.005486
72 TRANSCRIPTION COREPRESSOR ACTIVITY 14 221 0.0004857 0.006267
73 ACETYLTRANSFERASE ACTIVITY 9 103 0.0005123 0.006431
74 DAMAGED DNA BINDING 7 63 0.0005064 0.006431
75 N ACYLTRANSFERASE ACTIVITY 9 104 0.0005499 0.006812
76 TRANSFERASE ACTIVITY TRANSFERRING ONE CARBON GROUPS 14 225 0.0005804 0.007095
77 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 9 105 0.0005898 0.007116
78 NUCLEOTIDYLTRANSFERASE ACTIVITY 10 131 0.0007441 0.008862
79 N METHYLTRANSFERASE ACTIVITY 8 88 0.0008001 0.009409
NumGOOverlapSizeP ValueAdj. P Value
1 NUCLEAR CHROMOSOME 66 523 9.483e-31 5.538e-28
2 CHROMOSOME 83 880 1.726e-29 5.041e-27
3 CHROMATIN 57 441 3.909e-27 7.61e-25
4 NUCLEOPLASM PART 62 708 2.33e-20 3.401e-18
5 NUCLEAR CHROMATIN 40 291 2.918e-20 3.409e-18
6 TRANSFERASE COMPLEX 54 703 2.33e-15 2.268e-13
7 TRANSCRIPTION FACTOR COMPLEX 34 298 6.66e-15 5.556e-13
8 CATALYTIC COMPLEX 64 1038 1.586e-13 1.158e-11
9 CHROMOSOMAL REGION 32 330 3.731e-12 2.421e-10
10 HISTONE METHYLTRANSFERASE COMPLEX 15 71 4.129e-11 2.411e-09
11 NUCLEAR TRANSCRIPTION FACTOR COMPLEX 19 127 6.251e-11 3.319e-09
12 METHYLTRANSFERASE COMPLEX 16 90 1.448e-10 7.047e-09
13 TRANSFERASE COMPLEX TRANSFERRING PHOSPHORUS CONTAINING GROUPS 24 237 8.146e-10 3.591e-08
14 RNA POLYMERASE II TRANSCRIPTION FACTOR COMPLEX 16 101 8.609e-10 3.591e-08
15 RNA POLYMERASE COMPLEX 17 122 1.976e-09 7.693e-08
16 NUCLEOLUS 48 848 3.829e-09 1.397e-07
17 CHROMOSOME TELOMERIC REGION 19 162 4.267e-09 1.466e-07
18 SWI SNF SUPERFAMILY TYPE COMPLEX 13 71 5.364e-09 1.74e-07
19 PRONUCLEUS 7 15 1.488e-08 4.574e-07
20 CONDENSED CHROMOSOME 20 195 1.71e-08 4.992e-07
21 HETEROCHROMATIN 12 67 2.71e-08 7.537e-07
22 DNA DIRECTED RNA POLYMERASE II HOLOENZYME 14 97 3.361e-08 8.922e-07
23 NUCLEAR CHROMOSOME TELOMERIC REGION 16 132 4.493e-08 1.141e-06
24 ACETYLTRANSFERASE COMPLEX 14 100 4.996e-08 1.216e-06
25 CONDENSED NUCLEAR CHROMOSOME CENTROMERIC REGION 7 18 6.942e-08 1.622e-06
26 PROTEIN DNA COMPLEX 18 175 8.517e-08 1.913e-06
27 MICROTUBULE CYTOSKELETON 52 1068 1.193e-07 2.58e-06
28 SPINDLE 23 289 1.691e-07 3.526e-06
29 MICROTUBULE ORGANIZING CENTER 36 623 2.301e-07 4.634e-06
30 CONDENSED NUCLEAR CHROMOSOME 12 85 4.132e-07 8.043e-06
31 SPINDLE POLE 14 126 9.177e-07 1.729e-05
32 SEX CHROMOSOME 7 27 1.627e-06 2.969e-05
33 CENTROSOME 28 487 5.741e-06 9.861e-05
34 NUCLEAR HETEROCHROMATIN 7 32 5.597e-06 9.861e-05
35 CHROMOSOME CENTROMERIC REGION 15 174 9.189e-06 0.0001506
36 REPLICATION FORK 9 62 9.283e-06 0.0001506
37 RIBONUCLEOPROTEIN COMPLEX 35 721 1.655e-05 0.0002612
38 CYTOSKELETAL PART 57 1436 1.791e-05 0.0002693
39 CONDENSED CHROMOSOME CENTROMERIC REGION 11 102 1.799e-05 0.0002693
40 ESC E Z COMPLEX 5 16 1.964e-05 0.0002868
41 CHD TYPE COMPLEX 5 17 2.732e-05 0.0003891
42 MLL1 2 COMPLEX 6 28 3.028e-05 0.0004211
43 TRANSCRIPTIONAL REPRESSOR COMPLEX 9 74 3.99e-05 0.0005419
44 SPINDLE MICROTUBULE 8 58 4.277e-05 0.0005677
45 H4 HISTONE ACETYLTRANSFERASE COMPLEX 5 19 4.947e-05 0.000642
46 HISTONE DEACETYLASE COMPLEX 8 61 6.197e-05 0.0007868
47 CYTOSKELETON 70 1967 6.561e-05 0.0008153
48 MCM COMPLEX 4 11 7.235e-05 0.0008803
49 NUCLEAR TRANSCRIPTIONAL REPRESSOR COMPLEX 5 22 0.000106 0.001221
50 NPBAF COMPLEX 4 12 0.0001066 0.001221
51 CONDENSED CHROMOSOME OUTER KINETOCHORE 4 12 0.0001066 0.001221
52 NBAF COMPLEX 4 14 0.000208 0.002336
53 ADA2 GCN5 ADA3 TRANSCRIPTION ACTIVATOR COMPLEX 4 15 0.0002787 0.003014
54 SWI SNF COMPLEX 4 15 0.0002787 0.003014
55 SPINDLE MIDZONE 5 27 0.0002963 0.003146
56 KINETOCHORE 10 120 0.0003721 0.003881
57 DNA DIRECTED RNA POLYMERASE II CORE COMPLEX 4 17 0.0004689 0.004805
58 EUCHROMATIN 5 31 0.0005793 0.005833
59 CELL SUBSTRATE JUNCTION 20 398 0.0007053 0.006982
60 DNA PACKAGING COMPLEX 9 108 0.0007239 0.007046
61 MIDBODY 10 132 0.0007893 0.007557
62 GERM CELL NUCLEUS 4 20 0.0009052 0.008526

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04110_Cell_cycle 35 128 2.324e-28 4.184e-26
2 hsa04914_Progesterone.mediated_oocyte_maturation 15 87 8.563e-10 7.707e-08
3 hsa04114_Oocyte_meiosis 16 114 5.318e-09 3.191e-07
4 hsa03030_DNA_replication 7 36 1.285e-05 0.0005781
5 hsa04115_p53_signaling_pathway 9 69 2.258e-05 0.000813
6 hsa04722_Neurotrophin_signaling_pathway 12 127 2.895e-05 0.0008686
7 hsa03020_RNA_polymerase 6 29 3.746e-05 0.0009634
8 hsa00240_Pyrimidine_metabolism 10 99 7.572e-05 0.001704
9 hsa03410_Base_excision_repair 6 34 9.648e-05 0.00193
10 hsa04010_MAPK_signaling_pathway 17 268 0.0001234 0.002221
11 hsa04380_Osteoclast_differentiation 11 128 0.0001461 0.002391
12 hsa04390_Hippo_signaling_pathway 12 154 0.0001874 0.002811
13 hsa04370_VEGF_signaling_pathway 8 76 0.0002963 0.004102
14 hsa03420_Nucleotide_excision_repair 6 45 0.0004747 0.006104
15 hsa04330_Notch_signaling_pathway 6 47 0.0006027 0.007232
16 hsa04660_T_cell_receptor_signaling_pathway 9 108 0.0007239 0.008144
17 hsa04151_PI3K_AKT_signaling_pathway 18 351 0.001021 0.01081
18 hsa00230_Purine_metabolism 11 162 0.00109 0.0109
19 hsa04620_Toll.like_receptor_signaling_pathway 8 102 0.002082 0.01973
20 hsa04350_TGF.beta_signaling_pathway 7 85 0.002969 0.02672
21 hsa03440_Homologous_recombination 4 28 0.003321 0.02723
22 hsa04810_Regulation_of_actin_cytoskeleton 12 214 0.003328 0.02723
23 hsa03010_Ribosome 7 92 0.004613 0.03551
24 hsa04670_Leukocyte_transendothelial_migration 8 117 0.004852 0.03551
25 hsa03018_RNA_degradation 6 71 0.005129 0.03551
26 hsa04622_RIG.I.like_receptor_signaling_pathway 6 71 0.005129 0.03551
27 hsa04510_Focal_adhesion 11 200 0.005588 0.03725
28 hsa04520_Adherens_junction 6 73 0.005874 0.03776
29 hsa04662_B_cell_receptor_signaling_pathway 6 75 0.006694 0.04155
30 hsa03040_Spliceosome 8 128 0.008238 0.04943
31 hsa04664_Fc_epsilon_RI_signaling_pathway 6 79 0.008579 0.04982
32 hsa03022_Basal_transcription_factors 4 37 0.009148 0.05146
33 hsa04012_ErbB_signaling_pathway 6 87 0.01344 0.07217
34 hsa04141_Protein_processing_in_endoplasmic_reticulum 9 168 0.01363 0.07217
35 hsa04144_Endocytosis 10 203 0.01648 0.08478
36 hsa03013_RNA_transport 8 152 0.02138 0.1069
37 hsa00480_Glutathione_metabolism 4 50 0.02545 0.1235
38 hsa04912_GnRH_signaling_pathway 6 101 0.02607 0.1235
39 hsa04910_Insulin_signaling_pathway 7 138 0.03597 0.1607
40 hsa04340_Hedgehog_signaling_pathway 4 56 0.0366 0.1607
41 hsa04623_Cytosolic_DNA.sensing_pathway 4 56 0.0366 0.1607
42 hsa03450_Non.homologous_end.joining 2 14 0.03814 0.1634
43 hsa04014_Ras_signaling_pathway 10 236 0.0406 0.1699
44 hsa04621_NOD.like_receptor_signaling_pathway 4 59 0.04308 0.1762
45 hsa04062_Chemokine_signaling_pathway 8 189 0.06317 0.2527
46 hsa04960_Aldosterone.regulated_sodium_reabsorption 3 42 0.06746 0.264
47 hsa04720_Long.term_potentiation 4 70 0.07194 0.2716
48 hsa04360_Axon_guidance 6 130 0.07242 0.2716
49 hsa04973_Carbohydrate_digestion_and_absorption 3 44 0.07537 0.2769
50 hsa04650_Natural_killer_cell_mediated_cytotoxicity 6 136 0.08567 0.3084
51 hsa04120_Ubiquitin_mediated_proteolysis 6 139 0.09276 0.322
52 hsa03430_Mismatch_repair 2 23 0.09303 0.322
53 hsa04150_mTOR_signaling_pathway 3 52 0.1107 0.376
54 hsa04744_Phototransduction 2 29 0.137 0.4567
55 hsa04540_Gap_junction 4 90 0.1433 0.469
56 hsa04666_Fc_gamma_R.mediated_phagocytosis 4 95 0.1644 0.519
57 hsa00010_Glycolysis_._Gluconeogenesis 3 65 0.1784 0.5453
58 hsa04530_Tight_junction 5 133 0.1787 0.5453
59 hsa00051_Fructose_and_mannose_metabolism 2 36 0.1926 0.5684
60 hsa00270_Cysteine_and_methionine_metabolism 2 36 0.1926 0.5684
61 hsa04730_Long.term_depression 3 70 0.2069 0.582
62 hsa04260_Cardiac_muscle_contraction 3 77 0.2483 0.6877
63 hsa00310_Lysine_degradation 2 44 0.2589 0.706
64 hsa04145_Phagosome 5 156 0.272 0.7308
65 hsa03015_mRNA_surveillance_pathway 3 83 0.2847 0.7537
66 hsa04640_Hematopoietic_cell_lineage 3 88 0.3154 0.8228
67 hsa04210_Apoptosis 3 89 0.3215 0.8268
68 hsa00330_Arginine_and_proline_metabolism 2 54 0.3418 0.8665
69 hsa00562_Inositol_phosphate_metabolism 2 57 0.3662 0.9154
70 hsa04972_Pancreatic_secretion 3 101 0.3949 0.9606
71 hsa04310_Wnt_signaling_pathway 4 151 0.439 1
72 hsa04920_Adipocytokine_signaling_pathway 2 68 0.4522 1
73 hsa04630_Jak.STAT_signaling_pathway 4 155 0.4589 1
74 hsa04976_Bile_secretion 2 71 0.4745 1
75 hsa04270_Vascular_smooth_muscle_contraction 3 116 0.4833 1
76 hsa04971_Gastric_acid_secretion 2 74 0.4962 1
77 hsa04612_Antigen_processing_and_presentation 2 78 0.5243 1
78 hsa03008_Ribosome_biogenesis_in_eukaryotes 2 81 0.5446 1
79 hsa04916_Melanogenesis 2 101 0.6645 1
80 hsa04514_Cell_adhesion_molecules_.CAMs. 2 136 0.812 1
81 hsa04020_Calcium_signaling_pathway 2 177 0.9093 1

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1 TPRG1-AS1 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-125a-3p;hsa-miR-17-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-181c-5p;hsa-miR-181d-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-92a-3p;hsa-miR-92b-3p;hsa-miR-93-5p 14 KAT2B Sponge network -0.756 0.03021 -0.939 0 0.573
2 RP11-12A2.3 hsa-miR-106b-5p;hsa-miR-17-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-181c-5p;hsa-miR-181d-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-92a-3p;hsa-miR-92b-3p;hsa-miR-93-5p 13 KAT2B Sponge network -4.779 0 -0.939 0 0.539
3 AC004862.6 hsa-miR-106b-5p;hsa-miR-125a-3p;hsa-miR-17-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-181c-5p;hsa-miR-181d-5p;hsa-miR-19a-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-93-5p 11 KAT2B Sponge network -2.202 0.00081 -0.939 0 0.489
4 LINC00238 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-125a-3p;hsa-miR-17-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-181c-5p;hsa-miR-181d-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-20b-5p;hsa-miR-342-3p 13 KAT2B Sponge network -4.997 0 -0.939 0 0.478
5 AC005550.3 hsa-miR-17-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-181c-5p;hsa-miR-181d-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-92a-3p;hsa-miR-92b-3p 11 KAT2B Sponge network -2.571 0.00132 -0.939 0 0.44
6 RP11-166D19.1 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-590-5p;hsa-miR-92a-3p 10 KAT2B Sponge network -0.244 0.28835 -0.939 0 0.254

Quest ID: 4b18cc2cb6f4b8307fca2a113488a25c