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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-129-5p ACTB -2.57 0 0.4 0.01529 miRanda -0.11 0 NA
2 hsa-miR-7-1-3p ACTB 0.71 0.04123 0.4 0.01529 MirTarget -0.13 0.00011 NA
3 hsa-miR-199a-5p ACTG1 0.37 0.23266 0.18 0.35716 miRanda -0.13 0.00507 NA
4 hsa-miR-199b-5p ACTG1 0.12 0.67816 0.18 0.35716 miRanda -0.14 0.00274 NA
5 hsa-miR-127-5p AMOT 0.68 0.02163 -0.46 0.48869 PITA -0.45 0.00439 NA
6 hsa-miR-203a-3p AMOT 1.45 0.03941 -0.46 0.48869 MirTarget -0.22 0.00076 NA
7 hsa-miR-205-5p AMOT 3.14 0.02932 -0.46 0.48869 MirTarget; miRNATAP -0.2 0 26239614 MicroRNA 205 inhibits the proliferation and invasion of breast cancer by regulating AMOT expression; In the present study miR-205 was significantly downregulated in breast cancer samples and it was identified to directly target the 3'-untranslated region 3'-UTR of AMOT in breast cancer MCF-7 cells by luciferase assay; miR-205 and small interfering RNA siRNA-mediated AMOT-knockdown experiments revealed that miR-205 significantly inhibited the proliferation and the invasion of MCF-7 cells through a decrease in the expression of AMOT yet had no effect on apoptosis; Furthermore we observed that the overexpression of AMOT partially reversed the inhibitory effect of miR-205 on the growth and the invasion of MCF-7 cells; The data indicated that miR-205 regulated the proliferation and the invasion of breast cancer cells through suppression of AMOT expression at least partly; Therefore the disordered decreased expression of miR-205 and the resulting AMOT upregulation contributes to breast carcinogenesis and miR-205-AMOT represents a new potential therapeutic target for the treatment of breast carcinoma
8 hsa-miR-22-3p AMOT 0.03 0.84509 -0.46 0.48869 MirTarget; miRNATAP -1.74 0 NA
9 hsa-miR-2355-3p AMOT 0.98 0.02293 -0.46 0.48869 MirTarget; miRNATAP -0.63 0 NA
10 hsa-miR-34c-3p AMOT 2.25 9.0E-5 -0.46 0.48869 MirTarget; mirMAP -0.32 7.0E-5 NA
11 hsa-miR-34c-5p AMOT 2.21 0.00038 -0.46 0.48869 miRanda -0.27 0.00022 NA
12 hsa-miR-944 AMOT 3.33 0.01778 -0.46 0.48869 mirMAP; miRNATAP -0.26 0 NA
13 hsa-miR-106b-5p APC 1.71 0 -0.24 0.1992 miRNAWalker2 validate; miRTarBase -0.14 0.00091 23087084 miR 106b downregulates adenomatous polyposis coli and promotes cell proliferation in human hepatocellular carcinoma; Moreover we demonstrated that miR-106b downregulates APC expression by directly targeting the 3'-untranslated region of APC messenger RNA; Taken together our results suggest that miR-106b plays an important role in promoting the proliferation of human hepatoma cells and presents a novel mechanism of micro RNA-mediated direct suppression of APC expression in cancer cells
14 hsa-miR-107 APC 0.9 5.0E-5 -0.24 0.1992 miRanda -0.16 0.00649 NA
15 hsa-miR-320b APC 1.11 0.0005 -0.24 0.1992 miRanda -0.16 9.0E-5 NA
16 hsa-miR-20a-3p APC2 1.14 0.00045 -1.51 0.00013 mirMAP -0.27 0.0021 NA
17 hsa-miR-221-5p APC2 1.89 0 -1.51 0.00013 mirMAP -0.34 4.0E-5 NA
18 hsa-miR-345-5p APC2 1.84 0 -1.51 0.00013 mirMAP -0.29 0.00069 NA
19 hsa-miR-625-5p APC2 0.54 0.2038 -1.51 0.00013 mirMAP -0.31 0 NA
20 hsa-miR-129-5p AREG -2.57 0 0.46 0.44521 miRanda -0.38 0 NA
21 hsa-miR-205-5p AXIN2 3.14 0.02932 -0.66 0.25177 miRNATAP -0.17 0 NA
22 hsa-miR-34c-5p AXIN2 2.21 0.00038 -0.66 0.25177 miRanda -0.21 0.00103 NA
23 hsa-miR-944 AXIN2 3.33 0.01778 -0.66 0.25177 MirTarget; PITA; miRNATAP -0.2 0 NA
24 hsa-let-7a-2-3p BBC3 0.2 0.64356 1.16 0.00014 MirTarget -0.19 0.00032 NA
25 hsa-miR-149-5p BBC3 0.71 0.29685 1.16 0.00014 miRNATAP -0.13 7.0E-5 NA
26 hsa-miR-27b-3p BBC3 0.08 0.72527 1.16 0.00014 miRNATAP -0.25 0.00693 NA
27 hsa-miR-101-3p BIRC5 -0.45 0.02834 3.82 0 miRNAWalker2 validate -0.52 0.00033 NA
28 hsa-miR-10a-5p BIRC5 -0.47 0.1488 3.82 0 miRNAWalker2 validate -0.44 0 NA
29 hsa-miR-30c-5p BIRC5 -0.98 5.0E-5 3.82 0 miRNAWalker2 validate -0.45 0.00019 NA
30 hsa-miR-338-3p BIRC5 -0.96 0.01915 3.82 0 miRanda -0.28 8.0E-5 NA
31 hsa-miR-375 BIRC5 -2.95 0.0057 3.82 0 miRanda -0.11 2.0E-5 NA
32 hsa-miR-335-3p BMP2 2.52 0 -0.33 0.46013 mirMAP -0.23 0.00128 NA
33 hsa-miR-944 BMP5 3.33 0.01778 -2.34 0.00471 mirMAP -0.27 0 NA
34 hsa-miR-130b-3p BMP6 1.33 5.0E-5 -0.61 0.05079 MirTarget -0.18 0.00799 NA
35 hsa-miR-301b-3p BMP6 1.1 0.07156 -0.61 0.05079 MirTarget -0.17 0.00042 NA
36 hsa-miR-320a BMP6 0.59 0.0119 -0.61 0.05079 PITA; miRanda -0.28 0.00265 NA
37 hsa-miR-320c BMP6 0.46 0.24061 -0.61 0.05079 PITA; miRanda -0.19 0.00454 NA
38 hsa-miR-338-3p BMP7 -0.96 0.01915 0.77 0.31178 miRanda -0.54 3.0E-5 NA
39 hsa-miR-3614-3p BMP7 0.82 0.01436 0.77 0.31178 mirMAP -0.56 0.00079 NA
40 hsa-miR-362-3p BMP7 -0.03 0.91378 0.77 0.31178 miRanda -0.47 0.00508 NA
41 hsa-miR-142-5p BMPR1A 1.56 1.0E-5 -0.55 0.00086 MirTarget -0.14 2.0E-5 NA
42 hsa-miR-142-5p BMPR1B 1.56 1.0E-5 -2.08 0.00523 mirMAP -0.43 0.00503 NA
43 hsa-miR-16-2-3p BMPR1B 1.8 0 -2.08 0.00523 mirMAP -0.5 0.00295 NA
44 hsa-miR-2110 BMPR1B 0.76 0.0724 -2.08 0.00523 MirTarget -0.4 0.00168 NA
45 hsa-miR-29a-5p BMPR1B 0.59 0.02301 -2.08 0.00523 MirTarget; mirMAP; miRNATAP -0.8 0.0001 NA
46 hsa-miR-375 BMPR1B -2.95 0.0057 -2.08 0.00523 miRNATAP -0.13 0.00888 NA
47 hsa-miR-429 BMPR1B 1.4 0.009 -2.08 0.00523 miRNATAP -0.38 0.00012 NA
48 hsa-miR-501-5p BMPR1B 0.27 0.45478 -2.08 0.00523 mirMAP -0.46 0.00232 NA
49 hsa-miR-7-1-3p BMPR1B 0.71 0.04123 -2.08 0.00523 MirTarget -0.48 0.00173 NA
50 hsa-let-7f-1-3p BMPR2 1.29 0 -0.11 0.57571 MirTarget -0.18 0.0002 NA
51 hsa-miR-106b-5p BMPR2 1.71 0 -0.11 0.57571 MirTarget; miRNATAP -0.22 0 NA
52 hsa-miR-128-3p BMPR2 0.98 6.0E-5 -0.11 0.57571 miRNAWalker2 validate -0.22 3.0E-5 NA
53 hsa-miR-130b-3p BMPR2 1.33 5.0E-5 -0.11 0.57571 MirTarget; miRNATAP -0.18 0 NA
54 hsa-miR-148b-3p BMPR2 0.3 0.17466 -0.11 0.57571 mirMAP -0.26 2.0E-5 NA
55 hsa-miR-16-2-3p BMPR2 1.8 0 -0.11 0.57571 mirMAP -0.14 0.00112 NA
56 hsa-miR-17-5p BMPR2 1.66 0 -0.11 0.57571 miRNAWalker2 validate; MirTarget; TargetScan; miRNATAP -0.15 0.00037 NA
57 hsa-miR-182-5p BMPR2 0.89 0.03106 -0.11 0.57571 mirMAP -0.12 0.00029 NA
58 hsa-miR-185-5p BMPR2 1.14 0 -0.11 0.57571 MirTarget -0.2 0.00193 NA
59 hsa-miR-186-5p BMPR2 0.15 0.43471 -0.11 0.57571 mirMAP -0.23 0.0013 NA
60 hsa-miR-19a-3p BMPR2 1.27 0.00011 -0.11 0.57571 miRNAWalker2 validate; MirTarget; miRNATAP -0.1 0.00995 NA
61 hsa-miR-19b-3p BMPR2 0.76 0.00653 -0.11 0.57571 miRNAWalker2 validate; MirTarget; miRNATAP -0.13 0.00717 NA
62 hsa-miR-20a-5p BMPR2 1.45 0 -0.11 0.57571 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.12 0.00801 NA
63 hsa-miR-25-3p BMPR2 1.01 0.00042 -0.11 0.57571 miRNATAP -0.15 0.00153 NA
64 hsa-miR-26b-5p BMPR2 -0.3 0.16008 -0.11 0.57571 miRNAWalker2 validate -0.21 0.00095 NA
65 hsa-miR-301b-3p BMPR2 1.1 0.07156 -0.11 0.57571 MirTarget -0.13 1.0E-5 NA
66 hsa-miR-32-3p BMPR2 0.58 0.11837 -0.11 0.57571 mirMAP -0.12 0.00225 NA
67 hsa-miR-32-5p BMPR2 0.42 0.10646 -0.11 0.57571 miRNATAP -0.25 0 NA
68 hsa-miR-320b BMPR2 1.11 0.0005 -0.11 0.57571 mirMAP -0.16 0.0001 NA
69 hsa-miR-330-3p BMPR2 0.8 0.00747 -0.11 0.57571 PITA; miRNATAP -0.19 2.0E-5 NA
70 hsa-miR-335-3p BMPR2 2.52 0 -0.11 0.57571 mirMAP -0.13 1.0E-5 NA
71 hsa-miR-33a-3p BMPR2 0.35 0.32171 -0.11 0.57571 mirMAP -0.16 3.0E-5 NA
72 hsa-miR-33a-5p BMPR2 0.41 0.32143 -0.11 0.57571 mirMAP -0.2 0 NA
73 hsa-miR-33b-5p BMPR2 0.27 0.61481 -0.11 0.57571 mirMAP -0.15 0 NA
74 hsa-miR-361-5p BMPR2 0.41 0.01813 -0.11 0.57571 MirTarget; miRanda; mirMAP; miRNATAP -0.22 0.0062 NA
75 hsa-miR-374a-3p BMPR2 0.04 0.85148 -0.11 0.57571 MirTarget; miRNATAP -0.17 0.00497 NA
76 hsa-miR-378a-5p BMPR2 -0.56 0.03446 -0.11 0.57571 MirTarget -0.16 0.00197 NA
77 hsa-miR-424-3p BMPR2 0.86 0.02346 -0.11 0.57571 mirMAP -0.13 0.00031 NA
78 hsa-miR-532-5p BMPR2 0.31 0.25225 -0.11 0.57571 PITA -0.14 0.00563 NA
79 hsa-miR-582-3p BMPR2 -0.41 0.20294 -0.11 0.57571 PITA; miRNATAP -0.15 0.00018 NA
80 hsa-miR-590-3p BMPR2 1.12 0.00016 -0.11 0.57571 MirTarget; miRanda; mirMAP; miRNATAP -0.2 0 NA
81 hsa-miR-590-5p BMPR2 1.04 0.00027 -0.11 0.57571 MirTarget; PITA; miRNATAP -0.23 0 NA
82 hsa-miR-625-3p BMPR2 -0.19 0.62622 -0.11 0.57571 mirMAP -0.11 0.00206 NA
83 hsa-miR-629-5p BMPR2 1.06 0.00054 -0.11 0.57571 mirMAP -0.16 0.00021 NA
84 hsa-miR-671-5p BMPR2 0.95 0.00247 -0.11 0.57571 miRNATAP -0.12 0.0056 NA
85 hsa-miR-769-5p BMPR2 1.15 0 -0.11 0.57571 miRNATAP -0.23 3.0E-5 NA
86 hsa-miR-92a-3p BMPR2 1.22 1.0E-5 -0.11 0.57571 miRNAWalker2 validate; miRNATAP -0.2 2.0E-5 NA
87 hsa-miR-93-3p BMPR2 1.89 0 -0.11 0.57571 miRNAWalker2 validate -0.13 0.00045 NA
88 hsa-miR-96-5p BMPR2 1.14 0.00943 -0.11 0.57571 mirMAP -0.12 0.0001 NA
89 hsa-miR-103a-3p BTRC 0.84 0 -0.39 0.00796 MirTarget; miRNATAP -0.19 0.00257 NA
90 hsa-miR-148b-5p BTRC 1.04 0.00196 -0.39 0.00796 mirMAP -0.11 0.0005 NA
91 hsa-miR-15a-5p BTRC 1.04 0 -0.39 0.00796 miRNAWalker2 validate; MirTarget; miRNATAP -0.19 0.00011 NA
92 hsa-miR-15b-5p BTRC 1.62 0 -0.39 0.00796 MirTarget; miRNATAP -0.11 0.00209 NA
93 hsa-miR-16-1-3p BTRC 1.43 0 -0.39 0.00796 mirMAP -0.1 0.00835 NA
94 hsa-miR-16-5p BTRC 1.01 1.0E-5 -0.39 0.00796 miRNAWalker2 validate; MirTarget; miRNATAP -0.15 0.00163 NA
95 hsa-miR-320a BTRC 0.59 0.0119 -0.39 0.00796 miRNAWalker2 validate; PITA -0.16 0.00028 NA
96 hsa-miR-320b BTRC 1.11 0.0005 -0.39 0.00796 PITA -0.11 0.00036 NA
97 hsa-miR-454-3p BTRC 0.63 0.01349 -0.39 0.00796 mirMAP -0.19 0 NA
98 hsa-miR-505-3p BTRC 0.83 0.00112 -0.39 0.00796 MirTarget -0.12 0.00372 NA
99 hsa-miR-338-3p CCND1 -0.96 0.01915 0.62 0.1312 miRNAWalker2 validate; miRTarBase; miRanda -0.24 0.00086 NA
100 hsa-let-7a-3p CCND2 0.5 0.04111 -0.5 0.3 mirMAP -0.54 0.0001 20418948 MicroRNA let 7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2
101 hsa-let-7b-3p CCND2 0.22 0.29604 -0.5 0.3 mirMAP -0.46 0.00588 NA
102 hsa-miR-106b-5p CCND2 1.71 0 -0.5 0.3 miRNAWalker2 validate; miRTarBase; miRNATAP -0.42 9.0E-5 NA
103 hsa-miR-130b-5p CCND2 0.7 0.05101 -0.5 0.3 mirMAP -0.39 2.0E-5 NA
104 hsa-miR-141-3p CCND2 1.46 0.00116 -0.5 0.3 MirTarget; TargetScan -0.21 0.00436 NA
105 hsa-miR-15b-5p CCND2 1.62 0 -0.5 0.3 miRNATAP -0.44 0.00021 NA
106 hsa-miR-16-2-3p CCND2 1.8 0 -0.5 0.3 mirMAP -0.55 0 NA
107 hsa-miR-16-5p CCND2 1.01 1.0E-5 -0.5 0.3 miRNAWalker2 validate; miRNATAP -0.67 1.0E-5 NA
108 hsa-miR-181a-2-3p CCND2 0.9 0.00083 -0.5 0.3 mirMAP -0.38 0.00236 NA
109 hsa-miR-182-5p CCND2 0.89 0.03106 -0.5 0.3 miRNAWalker2 validate; miRTarBase; miRNATAP -0.32 9.0E-5 NA
110 hsa-miR-183-5p CCND2 1.66 0.00052 -0.5 0.3 miRNATAP -0.29 2.0E-5 NA
111 hsa-miR-19b-3p CCND2 0.76 0.00653 -0.5 0.3 miRNAWalker2 validate; MirTarget; miRNATAP -0.32 0.00853 NA
112 hsa-miR-21-3p CCND2 1.75 0 -0.5 0.3 mirMAP -0.33 0.0051 NA
113 hsa-miR-224-3p CCND2 1.52 0.0065 -0.5 0.3 mirMAP -0.27 4.0E-5 NA
114 hsa-miR-26b-5p CCND2 -0.3 0.16008 -0.5 0.3 mirMAP; miRNATAP -0.58 0.00034 NA
115 hsa-miR-301a-3p CCND2 1.45 1.0E-5 -0.5 0.3 miRNAWalker2 validate -0.38 0.0002 NA
116 hsa-miR-3065-3p CCND2 -1.04 0.02184 -0.5 0.3 MirTarget; miRNATAP -0.2 0.00685 NA
117 hsa-miR-3065-5p CCND2 -0.24 0.63312 -0.5 0.3 mirMAP -0.24 0.00057 NA
118 hsa-miR-424-5p CCND2 1.09 0.00042 -0.5 0.3 miRNATAP -0.39 0.0003 NA
119 hsa-miR-429 CCND2 1.4 0.009 -0.5 0.3 miRNATAP -0.19 0.002 NA
120 hsa-miR-450b-5p CCND2 0.46 0.13274 -0.5 0.3 MirTarget; PITA; miRNATAP -0.32 0.00413 NA
121 hsa-miR-590-3p CCND2 1.12 0.00016 -0.5 0.3 miRanda; mirMAP -0.33 0.00348 NA
122 hsa-miR-590-5p CCND2 1.04 0.00027 -0.5 0.3 mirMAP -0.41 0.00055 NA
123 hsa-miR-9-3p CCND2 0.33 0.54111 -0.5 0.3 MirTarget; mirMAP; miRNATAP -0.19 0.00361 NA
124 hsa-miR-93-5p CCND2 1.75 0 -0.5 0.3 miRNATAP -0.32 0.00244 NA
125 hsa-miR-96-5p CCND2 1.14 0.00943 -0.5 0.3 TargetScan; miRNATAP -0.33 3.0E-5 NA
126 hsa-miR-96-5p CCND3 1.14 0.00943 0.04 0.88352 TargetScan -0.12 0.00328 NA
127 hsa-miR-452-3p CRB2 2.2 0.00185 -0.85 0.10158 MirTarget -0.15 0.00972 NA
128 hsa-let-7b-5p CSNK1D 0.06 0.7814 -0.14 0.22914 miRNAWalker2 validate -0.11 0.00446 NA
129 hsa-miR-30a-3p CSNK1E -1.73 0 0.53 0.0008 miRNATAP -0.11 0.00091 NA
130 hsa-miR-30c-5p CSNK1E -0.98 5.0E-5 0.53 0.0008 miRNAWalker2 validate -0.18 0.0001 NA
131 hsa-miR-30d-3p CSNK1E -0.55 0.04337 0.53 0.0008 miRNATAP -0.14 0.00107 NA
132 hsa-miR-149-5p CTGF 0.71 0.29685 -1.48 0.00046 miRNATAP -0.15 0.00059 NA
133 hsa-miR-16-2-3p CTGF 1.8 0 -1.48 0.00046 MirTarget -0.68 0 NA
134 hsa-miR-18a-5p CTGF 2.2 0 -1.48 0.00046 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.38 0 23249750 Targeting of TGFβ signature and its essential component CTGF by miR 18 correlates with improved survival in glioblastoma; Indeed microRNA-18a but not other miR-17∼92 members has a functional site in the CTGF 3' UTR and its forced reexpression sharply reduces CTGF protein and mRNA levels; The unexpected effects of miR-18a on CTGF transcription are mediated in part by direct targeting of Smad3 and ensuing weakening of TGFβ signaling
135 hsa-miR-19a-3p CTGF 1.27 0.00011 -1.48 0.00046 MirTarget; miRNATAP -0.36 9.0E-5 NA
136 hsa-miR-19b-3p CTGF 0.76 0.00653 -1.48 0.00046 MirTarget; miRNATAP -0.42 0.00011 NA
137 hsa-miR-26b-3p CTGF -0.01 0.96577 -1.48 0.00046 MirTarget; miRNATAP -0.49 9.0E-5 25761878 Luciferase reporter assay confirmed the interaction of miR-26b with the 3' untranslated regions UTRs of CTGF and Smad1
138 hsa-miR-26b-5p CTGF -0.3 0.16008 -1.48 0.00046 miRNATAP -0.39 0.00727 25761878 Luciferase reporter assay confirmed the interaction of miR-26b with the 3' untranslated regions UTRs of CTGF and Smad1
139 hsa-miR-3065-5p CTGF -0.24 0.63312 -1.48 0.00046 MirTarget; miRNATAP -0.25 3.0E-5 NA
140 hsa-miR-330-3p CTGF 0.8 0.00747 -1.48 0.00046 MirTarget; PITA; miRNATAP -0.43 2.0E-5 NA
141 hsa-miR-3662 CTGF 1.83 0.0054 -1.48 0.00046 MirTarget; miRNATAP -0.17 0.00405 NA
142 hsa-miR-577 CTGF 0.91 0.22561 -1.48 0.00046 miRNATAP -0.12 0.00291 NA
143 hsa-miR-590-3p CTGF 1.12 0.00016 -1.48 0.00046 PITA; miRanda -0.45 1.0E-5 NA
144 hsa-miR-181c-5p CTNNA1 0.34 0.11293 -0.23 0.15019 MirTarget -0.17 0.00259 NA
145 hsa-miR-181d-5p CTNNA1 0.65 0.01434 -0.23 0.15019 MirTarget -0.15 0.00042 NA
146 hsa-miR-421 CTNNA1 1.81 0 -0.23 0.15019 miRanda -0.1 0.00152 NA
147 hsa-miR-21-3p CTNNA3 1.75 0 -2.21 0.00435 MirTarget -0.98 0 NA
148 hsa-miR-320b CTNNA3 1.11 0.0005 -2.21 0.00435 miRanda -0.61 0.00039 NA
149 hsa-miR-330-5p CTNNA3 0.49 0.05122 -2.21 0.00435 miRanda -0.76 0.00063 NA
150 hsa-miR-590-3p CTNNA3 1.12 0.00016 -2.21 0.00435 miRanda -1 0 NA
NumGOOverlapSizeP ValueAdj. P Value
1 CANONICAL WNT SIGNALING PATHWAY 28 95 4.847e-41 1.695e-37
2 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 66 1672 7.284e-41 1.695e-37
3 WNT SIGNALING PATHWAY 39 351 1.366e-39 2.118e-36
4 EPITHELIUM DEVELOPMENT 53 945 3.17e-39 2.95e-36
5 ORGAN MORPHOGENESIS 51 841 2.964e-39 2.95e-36
6 TISSUE DEVELOPMENT 62 1518 9.695e-39 7.519e-36
7 REGULATION OF WNT SIGNALING PATHWAY 37 310 1.16e-38 7.709e-36
8 REGULATION OF CELL DIFFERENTIATION 60 1492 7.179e-37 4.176e-34
9 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 54 1142 3.33e-36 1.722e-33
10 NEUROGENESIS 58 1402 4.251e-36 1.978e-33
11 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 32 236 3.81e-35 1.612e-32
12 REGULATION OF PROTEIN MODIFICATION PROCESS 61 1710 1.295e-34 5.02e-32
13 REGULATION OF PHOSPHORUS METABOLIC PROCESS 59 1618 8.718e-34 3.12e-31
14 POSITIVE REGULATION OF RESPONSE TO STIMULUS 63 1929 9.665e-34 3.212e-31
15 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 49 1021 9.304e-33 2.886e-30
16 TISSUE MORPHOGENESIS 39 533 1.741e-32 5.062e-30
17 POSITIVE REGULATION OF CELL DIFFERENTIATION 45 823 2.876e-32 7.873e-30
18 RESPONSE TO GROWTH FACTOR 37 475 9.71e-32 2.51e-29
19 POSITIVE REGULATION OF CELL COMMUNICATION 55 1532 9.085e-31 2.225e-28
20 TUBE DEVELOPMENT 37 552 2.283e-29 5.312e-27
21 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 57 1848 1.291e-28 2.861e-26
22 REGULATION OF CELL DEVELOPMENT 42 836 1.744e-28 3.689e-26
23 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 52 1492 3.149e-28 6.37e-26
24 REGULATION OF CELL PROLIFERATION 52 1496 3.579e-28 6.939e-26
25 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 41 801 4.454e-28 8.29e-26
26 POSITIVE REGULATION OF GENE EXPRESSION 55 1733 4.664e-28 8.347e-26
27 CELL FATE COMMITMENT 27 227 4.937e-28 8.509e-26
28 REGULATION OF STEM CELL DIFFERENTIATION 22 113 7.325e-28 1.217e-25
29 NEGATIVE REGULATION OF CELL COMMUNICATION 47 1192 1.627e-27 2.61e-25
30 EMBRYONIC MORPHOGENESIS 35 539 2.955e-27 4.583e-25
31 NEURON DIFFERENTIATION 41 874 1.316e-26 1.975e-24
32 REGULATION OF CELL DEATH 50 1472 1.733e-26 2.52e-24
33 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 48 1360 4.955e-26 6.987e-24
34 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 24 190 1.366e-25 1.869e-23
35 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 44 1135 2.681e-25 3.564e-23
36 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 42 1008 2.821e-25 3.646e-23
37 CELL DEVELOPMENT 48 1426 3.959e-25 4.979e-23
38 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 41 957 4.294e-25 5.258e-23
39 SENSORY ORGAN DEVELOPMENT 32 493 7.337e-25 8.753e-23
40 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 47 1395 1.453e-24 1.69e-22
41 REGULATION OF CELLULAR PROTEIN LOCALIZATION 33 552 1.627e-24 1.847e-22
42 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 52 1805 2.531e-24 2.804e-22
43 EMBRYO DEVELOPMENT 39 894 4.408e-24 4.77e-22
44 MORPHOGENESIS OF AN EPITHELIUM 29 400 7.274e-24 7.692e-22
45 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 17 67 7.446e-24 7.699e-22
46 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 41 1036 8.759e-24 8.672e-22
47 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 41 1036 8.759e-24 8.672e-22
48 CARTILAGE DEVELOPMENT 21 147 1.27e-23 1.231e-21
49 GROWTH 29 410 1.464e-23 1.39e-21
50 POSITIVE REGULATION OF CELL DEVELOPMENT 30 472 5.024e-23 4.598e-21
51 REGULATION OF ORGAN MORPHOGENESIS 24 242 5.04e-23 4.598e-21
52 CARDIOVASCULAR SYSTEM DEVELOPMENT 36 788 8.055e-23 7.072e-21
53 CIRCULATORY SYSTEM DEVELOPMENT 36 788 8.055e-23 7.072e-21
54 REGULATION OF CARTILAGE DEVELOPMENT 16 63 1.638e-22 1.411e-20
55 CONNECTIVE TISSUE DEVELOPMENT 22 194 1.914e-22 1.619e-20
56 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 15 50 2.105e-22 1.749e-20
57 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 22 197 2.699e-22 2.203e-20
58 NEGATIVE REGULATION OF CELL DIFFERENTIATION 32 609 4.764e-22 3.821e-20
59 RESPONSE TO ENDOGENOUS STIMULUS 45 1450 5.739e-22 4.526e-20
60 REGULATION OF OSSIFICATION 21 178 8.045e-22 6.239e-20
61 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 38 983 1.368e-21 1.043e-19
62 TUBE MORPHOGENESIS 25 323 2.717e-21 2.039e-19
63 NEGATIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 20 162 3.215e-21 2.375e-19
64 POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 13 34 3.523e-21 2.561e-19
65 REGULATION OF PROTEIN LOCALIZATION 37 950 4.17e-21 2.985e-19
66 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 40 1152 4.31e-21 3.038e-19
67 POSITIVE REGULATION OF CELL DEATH 31 605 4.959e-21 3.444e-19
68 ESTABLISHMENT OR MAINTENANCE OF CELL POLARITY 19 141 6.093e-21 4.169e-19
69 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 29 513 7.688e-21 5.185e-19
70 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 19 144 9.216e-21 6.051e-19
71 CELL PROLIFERATION 32 672 9.233e-21 6.051e-19
72 HIPPO SIGNALING 12 27 1.305e-20 8.434e-19
73 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 21 207 2.003e-20 1.277e-18
74 REGULATION OF EPITHELIAL CELL PROLIFERATION 23 285 4.904e-20 3.084e-18
75 REGULATION OF CELL MORPHOGENESIS 29 552 5.765e-20 3.576e-18
76 REGULATION OF MAPK CASCADE 31 660 6.226e-20 3.812e-18
77 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 29 554 6.365e-20 3.846e-18
78 CELLULAR COMPONENT MORPHOGENESIS 35 900 6.653e-20 3.969e-18
79 REGULATION OF OSTEOBLAST DIFFERENTIATION 17 112 9.606e-20 5.658e-18
80 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 24 337 1.309e-19 7.616e-18
81 REGULATION OF CELLULAR LOCALIZATION 40 1277 1.737e-19 9.977e-18
82 REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 14 60 3.013e-19 1.71e-17
83 NEGATIVE REGULATION OF CELL PROLIFERATION 30 643 3.327e-19 1.865e-17
84 POSITIVE REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 13 48 6.849e-19 3.794e-17
85 EMBRYONIC ORGAN DEVELOPMENT 25 406 6.968e-19 3.815e-17
86 SKELETAL SYSTEM DEVELOPMENT 26 455 8.089e-19 4.377e-17
87 PATTERN SPECIFICATION PROCESS 25 418 1.399e-18 7.481e-17
88 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 45 1784 2.091e-18 1.106e-16
89 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 35 1004 2.135e-18 1.116e-16
90 POSITIVE REGULATION OF CELL PROLIFERATION 32 814 2.672e-18 1.381e-16
91 HEAD DEVELOPMENT 30 709 5.013e-18 2.563e-16
92 GLAND DEVELOPMENT 24 395 5.172e-18 2.616e-16
93 SMAD PROTEIN SIGNAL TRANSDUCTION 13 56 6.456e-18 3.23e-16
94 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 15 95 8.333e-18 4.125e-16
95 REGULATION OF INTRACELLULAR TRANSPORT 28 621 1.526e-17 7.474e-16
96 EYE DEVELOPMENT 22 326 1.595e-17 7.731e-16
97 POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 15 100 1.868e-17 8.959e-16
98 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 29 689 2.295e-17 1.09e-15
99 DEVELOPMENTAL GROWTH 22 333 2.504e-17 1.177e-15
100 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 19 218 2.664e-17 1.24e-15
101 CELL JUNCTION ORGANIZATION 18 185 2.716e-17 1.251e-15
102 GASTRULATION 17 155 2.842e-17 1.296e-15
103 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 19 220 3.163e-17 1.429e-15
104 MESENCHYME DEVELOPMENT 18 190 4.389e-17 1.964e-15
105 POSITIVE REGULATION OF OSSIFICATION 14 84 4.915e-17 2.178e-15
106 REGULATION OF KINASE ACTIVITY 30 776 5.954e-17 2.614e-15
107 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 17 162 6.068e-17 2.639e-15
108 EPITHELIAL CELL DIFFERENTIATION 25 495 7.626e-17 3.286e-15
109 MESENCHYME MORPHOGENESIS 11 38 1.623e-16 6.927e-15
110 CELL CYCLE 37 1316 1.983e-16 8.39e-15
111 REGULATION OF TRANSFERASE ACTIVITY 32 946 2.04e-16 8.552e-15
112 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 29 750 2.164e-16 8.992e-15
113 MESODERM DEVELOPMENT 15 118 2.448e-16 1.008e-14
114 REGULATION OF GROWTH 27 633 2.519e-16 1.028e-14
115 RESPONSE TO BMP 14 94 2.573e-16 1.032e-14
116 CELLULAR RESPONSE TO BMP STIMULUS 14 94 2.573e-16 1.032e-14
117 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 24 470 2.687e-16 1.068e-14
118 OSSIFICATION 19 251 3.709e-16 1.462e-14
119 REGULATION OF PROTEIN IMPORT 17 183 4.838e-16 1.892e-14
120 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 16 154 6.202e-16 2.405e-14
121 CHONDROCYTE DIFFERENTIATION 12 60 8.962e-16 3.446e-14
122 STEM CELL DIFFERENTIATION 17 190 9.123e-16 3.48e-14
123 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 15 131 1.214e-15 4.594e-14
124 PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 8 13 1.259e-15 4.724e-14
125 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 33 1087 1.446e-15 5.382e-14
126 RESPIRATORY SYSTEM DEVELOPMENT 17 197 1.677e-15 6.194e-14
127 NEGATIVE REGULATION OF GROWTH 18 236 2.069e-15 7.521e-14
128 REGULATION OF APOPTOTIC SIGNALING PATHWAY 21 363 2.055e-15 7.521e-14
129 MORPHOGENESIS OF A BRANCHING STRUCTURE 16 167 2.276e-15 8.208e-14
130 FORMATION OF PRIMARY GERM LAYER 14 110 2.512e-15 8.894e-14
131 CELLULAR RESPONSE TO RETINOIC ACID 12 65 2.518e-15 8.894e-14
132 HEART DEVELOPMENT 23 466 2.523e-15 8.894e-14
133 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 38 1517 2.96e-15 1.036e-13
134 MESODERM MORPHOGENESIS 12 66 3.063e-15 1.064e-13
135 NON CANONICAL WNT SIGNALING PATHWAY 15 140 3.332e-15 1.14e-13
136 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 16 171 3.32e-15 1.14e-13
137 HEART MORPHOGENESIS 17 212 5.73e-15 1.946e-13
138 MAMMARY GLAND DEVELOPMENT 14 117 6.081e-15 2.05e-13
139 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 39 1656 8.558e-15 2.865e-13
140 UROGENITAL SYSTEM DEVELOPMENT 19 299 9.24e-15 3.071e-13
141 NEGATIVE REGULATION OF GENE EXPRESSION 37 1493 1.084e-14 3.578e-13
142 PROTEIN PHOSPHORYLATION 30 944 1.139e-14 3.731e-13
143 POSITIVE REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 10 38 1.196e-14 3.893e-13
144 RESPONSE TO LIPID 29 888 1.73e-14 5.591e-13
145 EPITHELIAL TO MESENCHYMAL TRANSITION 11 56 1.841e-14 5.907e-13
146 REGIONALIZATION 19 311 1.888e-14 6.017e-13
147 CELL DIVISION 22 460 2.087e-14 6.606e-13
148 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 20 360 2.201e-14 6.921e-13
149 EMBRYONIC ORGAN MORPHOGENESIS 18 279 3.82e-14 1.193e-12
150 MESENCHYMAL CELL DIFFERENTIATION 14 134 4.166e-14 1.292e-12
151 SKELETAL SYSTEM MORPHOGENESIS 16 201 4.272e-14 1.317e-12
152 RESPONSE TO RETINOIC ACID 13 107 4.843e-14 1.483e-12
153 NEGATIVE REGULATION OF MOLECULAR FUNCTION 31 1079 5.665e-14 1.723e-12
154 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 23 541 5.996e-14 1.8e-12
155 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 23 541 5.996e-14 1.8e-12
156 PALATE DEVELOPMENT 12 85 7.47e-14 2.228e-12
157 NEGATIVE REGULATION OF CELL DEATH 28 872 8.131e-14 2.394e-12
158 CENTRAL NERVOUS SYSTEM DEVELOPMENT 28 872 8.131e-14 2.394e-12
159 REGULATION OF CHONDROCYTE DIFFERENTIATION 10 46 9.924e-14 2.904e-12
160 POSITIVE REGULATION OF MOLECULAR FUNCTION 39 1791 1.084e-13 3.153e-12
161 REGULATION OF EMBRYONIC DEVELOPMENT 13 114 1.12e-13 3.238e-12
162 RHYTHMIC PROCESS 18 298 1.186e-13 3.406e-12
163 LENS DEVELOPMENT IN CAMERA TYPE EYE 11 66 1.265e-13 3.612e-12
164 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 22 514 1.977e-13 5.574e-12
165 REGULATION OF PROTEIN TARGETING 18 307 1.973e-13 5.574e-12
166 RESPONSE TO OXYGEN CONTAINING COMPOUND 34 1381 2.172e-13 6.089e-12
167 REPRODUCTIVE SYSTEM DEVELOPMENT 20 408 2.296e-13 6.396e-12
168 REGULATION OF CELLULAR COMPONENT MOVEMENT 26 771 2.412e-13 6.681e-12
169 POSITIVE REGULATION OF WNT SIGNALING PATHWAY 14 152 2.432e-13 6.695e-12
170 IN UTERO EMBRYONIC DEVELOPMENT 18 311 2.46e-13 6.734e-12
171 POSITIVE REGULATION OF MAPK CASCADE 21 470 3.262e-13 8.877e-12
172 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 19 365 3.343e-13 9.045e-12
173 CELL CYCLE PROCESS 30 1081 3.875e-13 1.042e-11
174 OSTEOBLAST DIFFERENTIATION 13 126 4.167e-13 1.114e-11
175 ANTERIOR POSTERIOR PATTERN SPECIFICATION 15 194 4.289e-13 1.14e-11
176 MAMMARY GLAND EPITHELIUM DEVELOPMENT 10 53 4.589e-13 1.213e-11
177 POSITIVE REGULATION OF KINASE ACTIVITY 21 482 5.301e-13 1.393e-11
178 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 15 197 5.369e-13 1.403e-11
179 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 23 602 5.56e-13 1.445e-11
180 REGULATION OF CELL CYCLE 28 949 6.406e-13 1.656e-11
181 REGULATION OF BINDING 17 283 6.582e-13 1.692e-11
182 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 19 381 7.153e-13 1.829e-11
183 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 23 616 8.937e-13 2.272e-11
184 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 13 135 1.023e-12 2.586e-11
185 REGULATION OF FAT CELL DIFFERENTIATION 12 106 1.129e-12 2.84e-11
186 INTRACELLULAR SIGNAL TRANSDUCTION 35 1572 1.607e-12 4.021e-11
187 STEM CELL PROLIFERATION 10 60 1.715e-12 4.268e-11
188 PHOSPHORYLATION 31 1228 1.724e-12 4.268e-11
189 CELLULAR MACROMOLECULE LOCALIZATION 31 1234 1.958e-12 4.819e-11
190 NEGATIVE REGULATION OF CELL DEVELOPMENT 17 303 1.976e-12 4.838e-11
191 REGULATION OF SMAD PROTEIN IMPORT INTO NUCLEUS 7 16 2.014e-12 4.881e-11
192 PARAXIAL MESODERM DEVELOPMENT 7 16 2.014e-12 4.881e-11
193 REGULATION OF CATENIN IMPORT INTO NUCLEUS 8 27 2.03e-12 4.894e-11
194 ESTABLISHMENT OF CELL POLARITY 11 88 3.39e-12 8.09e-11
195 REGULATION OF STEM CELL PROLIFERATION 11 88 3.39e-12 8.09e-11
196 REGULATION OF ORGANELLE ORGANIZATION 30 1178 3.45e-12 8.191e-11
197 POSITIVE REGULATION OF CARTILAGE DEVELOPMENT 8 29 3.887e-12 9.182e-11
198 MIDBRAIN DEVELOPMENT 11 90 4.365e-12 1.026e-10
199 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 18 370 4.609e-12 1.078e-10
200 REGULATION OF CYTOPLASMIC TRANSPORT 20 481 4.727e-12 1.1e-10
201 LOCOMOTION 29 1114 5.043e-12 1.167e-10
202 REPRODUCTION 31 1297 7.091e-12 1.633e-10
203 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 22 616 7.155e-12 1.64e-10
204 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 19 437 7.905e-12 1.803e-10
205 REGULATION OF CELL ADHESION 22 629 1.075e-11 2.441e-10
206 REGULATION OF DEVELOPMENTAL GROWTH 16 289 1.135e-11 2.55e-10
207 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 16 289 1.135e-11 2.55e-10
208 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 38 1977 1.156e-11 2.587e-10
209 CELL JUNCTION ASSEMBLY 12 129 1.201e-11 2.674e-10
210 REGULATION OF TRANSPORT 36 1804 1.687e-11 3.738e-10
211 REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 10 75 1.754e-11 3.868e-10
212 PROTEIN COMPLEX SUBUNIT ORGANIZATION 33 1527 1.881e-11 4.128e-10
213 RESPONSE TO ABIOTIC STIMULUS 27 1024 2.393e-11 5.227e-10
214 ODONTOGENESIS 11 105 2.431e-11 5.286e-10
215 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 30 1275 2.487e-11 5.382e-10
216 POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 8 36 2.65e-11 5.708e-10
217 VASCULATURE DEVELOPMENT 19 469 2.677e-11 5.741e-10
218 BETA CATENIN DESTRUCTION COMPLEX DISASSEMBLY 7 22 2.918e-11 6.227e-10
219 POSITIVE REGULATION OF SMAD PROTEIN IMPORT INTO NUCLEUS 6 12 3e-11 6.375e-10
220 NEGATIVE REGULATION OF PHOSPHORYLATION 18 422 4.054e-11 8.575e-10
221 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 17 368 4.29e-11 9.033e-10
222 NEURON PROJECTION DEVELOPMENT 20 545 4.472e-11 9.372e-10
223 REGULATION OF MAP KINASE ACTIVITY 16 319 4.973e-11 1.038e-09
224 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 24 829 5.611e-11 1.165e-09
225 NEURON DEVELOPMENT 22 687 5.91e-11 1.222e-09
226 NEGATIVE REGULATION OF CELL CYCLE 18 433 6.175e-11 1.271e-09
227 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 9 60 6.255e-11 1.282e-09
228 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 14 229 6.448e-11 1.316e-09
229 APICAL JUNCTION ASSEMBLY 8 40 6.606e-11 1.336e-09
230 REGULATION OF CELLULAR RESPONSE TO STRESS 22 691 6.605e-11 1.336e-09
231 REGULATION OF HYDROLASE ACTIVITY 30 1327 6.647e-11 1.339e-09
232 RESPONSE TO ORGANIC CYCLIC COMPOUND 25 917 7.468e-11 1.498e-09
233 POSITIVE REGULATION OF CATALYTIC ACTIVITY 32 1518 7.891e-11 1.576e-09
234 CELL DEATH 26 1001 8.373e-11 1.665e-09
235 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 12 153 9.025e-11 1.787e-09
236 CELL ACTIVATION 20 568 9.312e-11 1.836e-09
237 MESONEPHROS DEVELOPMENT 10 90 1.126e-10 2.211e-09
238 REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 8 43 1.228e-10 2.4e-09
239 KIDNEY EPITHELIUM DEVELOPMENT 11 125 1.643e-10 3.198e-09
240 NEURON PROJECTION MORPHOGENESIS 17 402 1.694e-10 3.284e-09
241 GLAND MORPHOGENESIS 10 97 2.393e-10 4.62e-09
242 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 22 740 2.43e-10 4.673e-09
243 REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 7 29 2.582e-10 4.904e-09
244 POSITIVE REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 7 29 2.582e-10 4.904e-09
245 STEM CELL DIVISION 7 29 2.582e-10 4.904e-09
246 CELL CYCLE PHASE TRANSITION 14 255 2.675e-10 5.06e-09
247 APPENDAGE DEVELOPMENT 12 169 2.877e-10 5.397e-09
248 LIMB DEVELOPMENT 12 169 2.877e-10 5.397e-09
249 BLOOD VESSEL MORPHOGENESIS 16 364 3.478e-10 6.478e-09
250 PROTEIN LOCALIZATION 34 1805 3.48e-10 6.478e-09
251 REGULATION OF ORGAN GROWTH 9 73 3.858e-10 7.152e-09
252 CELLULAR RESPONSE TO ACID CHEMICAL 12 175 4.307e-10 7.953e-09
253 REGULATION OF MUSCLE TISSUE DEVELOPMENT 10 103 4.36e-10 7.976e-09
254 REGULATION OF MUSCLE ORGAN DEVELOPMENT 10 103 4.36e-10 7.976e-09
255 CELL CELL JUNCTION ASSEMBLY 9 74 4.371e-10 7.976e-09
256 REGULATION OF NEURON DIFFERENTIATION 19 554 4.502e-10 8.183e-09
257 CELL CYCLE G2 M PHASE TRANSITION 11 138 4.785e-10 8.664e-09
258 RESPONSE TO ACID CHEMICAL 15 319 5.113e-10 9.221e-09
259 REGULATION OF ORGAN FORMATION 7 32 5.489e-10 9.824e-09
260 BICELLULAR TIGHT JUNCTION ASSEMBLY 7 32 5.489e-10 9.824e-09
261 RESPONSE TO WOUNDING 19 563 5.891e-10 1.05e-08
262 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 19 573 7.895e-10 1.402e-08
263 REGULATION OF ESTABLISHMENT OF PLANAR POLARITY 10 110 8.38e-10 1.483e-08
264 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 23 876 1.007e-09 1.775e-08
265 DIGESTIVE SYSTEM DEVELOPMENT 11 148 1.013e-09 1.778e-08
266 PROTEIN COMPLEX BIOGENESIS 26 1132 1.174e-09 2.047e-08
267 PROTEIN COMPLEX ASSEMBLY 26 1132 1.174e-09 2.047e-08
268 CELLULAR RESPONSE TO LIPID 17 457 1.203e-09 2.088e-08
269 SINGLE ORGANISM CELL ADHESION 17 459 1.285e-09 2.223e-08
270 SENSORY ORGAN MORPHOGENESIS 13 239 1.355e-09 2.335e-08
271 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 9 84 1.387e-09 2.382e-08
272 EMBRYONIC PATTERN SPECIFICATION 8 58 1.51e-09 2.583e-08
273 CELL CYCLE ARREST 11 154 1.546e-09 2.636e-08
274 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 16 404 1.576e-09 2.676e-08
275 POSITIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 10 119 1.82e-09 3.08e-08
276 WOUND HEALING 17 470 1.837e-09 3.097e-08
277 REGULATION OF DEPHOSPHORYLATION 11 158 2.03e-09 3.41e-08
278 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 10 121 2.144e-09 3.588e-08
279 REGULATION OF JNK CASCADE 11 159 2.17e-09 3.62e-08
280 ACTIVIN RECEPTOR SIGNALING PATHWAY 6 22 2.311e-09 3.827e-08
281 SOMATIC STEM CELL DIVISION 6 22 2.311e-09 3.827e-08
282 SEGMENTATION 9 89 2.338e-09 3.858e-08
283 FOREBRAIN DEVELOPMENT 15 357 2.39e-09 3.93e-08
284 WNT SIGNALING PATHWAY CALCIUM MODULATING PATHWAY 7 39 2.426e-09 3.975e-08
285 SOMITOGENESIS 8 62 2.613e-09 4.266e-08
286 POSITIVE REGULATION OF LOCOMOTION 16 420 2.749e-09 4.473e-08
287 DORSAL VENTRAL PATTERN FORMATION 9 91 2.856e-09 4.63e-08
288 REGULATION OF RESPONSE TO STRESS 29 1468 3.399e-09 5.491e-08
289 POSITIVE REGULATION OF TRANSPORT 23 936 3.567e-09 5.743e-08
290 REGULATION OF PROTEIN BINDING 11 168 3.882e-09 6.229e-08
291 CELL PART MORPHOGENESIS 19 633 4.062e-09 6.495e-08
292 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 13 262 4.124e-09 6.558e-08
293 CARDIAC EPITHELIAL TO MESENCHYMAL TRANSITION 6 24 4.13e-09 6.558e-08
294 NEGATIVE REGULATION OF CELL GROWTH 11 170 4.397e-09 6.959e-08
295 REGULATION OF PROTEOLYSIS 20 711 4.551e-09 7.178e-08
296 MAMMARY GLAND EPITHELIAL CELL PROLIFERATION 5 12 4.614e-09 7.253e-08
297 SEX DIFFERENTIATION 13 266 4.949e-09 7.753e-08
298 NEGATIVE REGULATION OF STEM CELL DIFFERENTIATION 7 43 4.986e-09 7.786e-08
299 LENS FIBER CELL DIFFERENTIATION 6 25 5.408e-09 8.416e-08
300 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 21 799 5.884e-09 9.127e-08
301 REGULATION OF PROTEIN STABILITY 12 221 6.159e-09 9.521e-08
302 NEURAL PRECURSOR CELL PROLIFERATION 8 70 7.02e-09 1.078e-07
303 REGULATION OF MEMBRANE PERMEABILITY 8 70 7.02e-09 1.078e-07
304 NEGATIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 8 71 7.873e-09 1.205e-07
305 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 9 102 7.913e-09 1.207e-07
306 REGULATION OF CELL GROWTH 15 391 8.16e-09 1.241e-07
307 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 12 228 8.739e-09 1.324e-07
308 DEVELOPMENTAL INDUCTION 6 27 8.955e-09 1.348e-07
309 AXIS ELONGATION 6 27 8.955e-09 1.348e-07
310 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 9 104 9.401e-09 1.411e-07
311 CELL PROJECTION ORGANIZATION 22 902 9.435e-09 1.412e-07
312 REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 8 73 9.852e-09 1.469e-07
313 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 7 48 1.112e-08 1.654e-07
314 REGULATION OF HEART MORPHOGENESIS 6 29 1.423e-08 2.109e-07
315 NEURAL TUBE DEVELOPMENT 10 149 1.615e-08 2.386e-07
316 SOMITE DEVELOPMENT 8 78 1.678e-08 2.47e-07
317 ESTABLISHMENT OR MAINTENANCE OF EPITHELIAL CELL APICAL BASAL POLARITY 6 30 1.771e-08 2.599e-07
318 MACROMOLECULAR COMPLEX ASSEMBLY 27 1398 2.16e-08 3.161e-07
319 RESPONSE TO ALCOHOL 14 362 2.407e-08 3.512e-07
320 POSITIVE REGULATION OF NEURON DIFFERENTIATION 13 306 2.623e-08 3.814e-07
321 NEGATIVE REGULATION OF CYTOPLASMIC TRANSPORT 9 117 2.654e-08 3.835e-07
322 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 9 117 2.654e-08 3.835e-07
323 POSITIVE REGULATION OF MAP KINASE ACTIVITY 11 207 3.407e-08 4.907e-07
324 BRANCH ELONGATION OF AN EPITHELIUM 5 17 3.522e-08 5.058e-07
325 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 9 121 3.561e-08 5.098e-07
326 RESPONSE TO HORMONE 21 893 4.026e-08 5.746e-07
327 ENDOCRINE SYSTEM DEVELOPMENT 9 123 4.108e-08 5.846e-07
328 SKIN DEVELOPMENT 11 211 4.146e-08 5.881e-07
329 IMMUNE SYSTEM DEVELOPMENT 17 582 4.317e-08 6.105e-07
330 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 9 126 5.067e-08 7.144e-07
331 AXIS SPECIFICATION 8 90 5.235e-08 7.36e-07
332 NEGATIVE REGULATION OF MUSCLE ORGAN DEVELOPMENT 6 36 5.647e-08 7.891e-07
333 NEGATIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 6 36 5.647e-08 7.891e-07
334 RESPONSE TO ESTROGEN 11 218 5.789e-08 8.064e-07
335 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 9 129 6.215e-08 8.623e-07
336 MITOCHONDRIAL MEMBRANE ORGANIZATION 8 92 6.227e-08 8.623e-07
337 CELL MOTILITY 20 835 6.58e-08 9.058e-07
338 LOCALIZATION OF CELL 20 835 6.58e-08 9.058e-07
339 REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION 6 37 6.708e-08 9.154e-07
340 ESTABLISHMENT OR MAINTENANCE OF APICAL BASAL CELL POLARITY 6 37 6.708e-08 9.154e-07
341 ESTABLISHMENT OR MAINTENANCE OF BIPOLAR CELL POLARITY 6 37 6.708e-08 9.154e-07
342 POSITIVE REGULATION OF CELL CYCLE 13 332 6.818e-08 9.276e-07
343 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 15 465 8.046e-08 1.085e-06
344 NEGATIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 8 95 8.015e-08 1.085e-06
345 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 18 684 8.048e-08 1.085e-06
346 MITOTIC CELL CYCLE 19 766 8.509e-08 1.144e-06
347 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 9 134 8.636e-08 1.158e-06
348 REGULATION OF CELLULAR COMPONENT BIOGENESIS 19 767 8.684e-08 1.16e-06
349 DORSAL VENTRAL AXIS SPECIFICATION 5 20 8.703e-08 1.16e-06
350 REGULATION OF DNA METABOLIC PROCESS 13 340 8.99e-08 1.195e-06
351 NEGATIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 9 135 9.209e-08 1.221e-06
352 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 14 406 9.979e-08 1.319e-06
353 CIRCADIAN RHYTHM 9 137 1.045e-07 1.378e-06
354 NEGATIVE REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 7 66 1.08e-07 1.415e-06
355 NEGATIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 7 66 1.08e-07 1.415e-06
356 MAMMARY GLAND MORPHOGENESIS 6 40 1.092e-07 1.423e-06
357 NEGATIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 6 40 1.092e-07 1.423e-06
358 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 8 99 1.107e-07 1.435e-06
359 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 8 99 1.107e-07 1.435e-06
360 NEGATIVE REGULATION OF ORGAN GROWTH 5 21 1.137e-07 1.47e-06
361 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 6 41 1.273e-07 1.641e-06
362 POSITIVE REGULATION OF GROWTH 11 238 1.411e-07 1.813e-06
363 ENDOCARDIAL CUSHION MORPHOGENESIS 5 22 1.465e-07 1.877e-06
364 NEGATIVE REGULATION OF OSSIFICATION 7 69 1.475e-07 1.885e-06
365 REGULATION OF CIRCADIAN RHYTHM 8 103 1.509e-07 1.921e-06
366 NEGATIVE REGULATION OF INTRACELLULAR TRANSPORT 9 143 1.511e-07 1.921e-06
367 POSITIVE REGULATION OF PROTEIN IMPORT 8 104 1.626e-07 2.062e-06
368 BETA CATENIN TCF COMPLEX ASSEMBLY 6 43 1.71e-07 2.162e-06
369 ENDODERM DEVELOPMENT 7 71 1.8e-07 2.27e-06
370 MALE SEX DIFFERENTIATION 9 148 2.027e-07 2.549e-06
371 EAR DEVELOPMENT 10 195 2.053e-07 2.574e-06
372 REGULATION OF CYTOSKELETON ORGANIZATION 15 502 2.16e-07 2.701e-06
373 MEMBRANE ORGANIZATION 20 899 2.165e-07 2.701e-06
374 NEGATIVE REGULATION OF KINASE ACTIVITY 11 250 2.313e-07 2.877e-06
375 EPIDERMIS DEVELOPMENT 11 253 2.606e-07 3.234e-06
376 RESPONSE TO OXYGEN LEVELS 12 311 2.629e-07 3.253e-06
377 ODONTOGENESIS OF DENTIN CONTAINING TOOTH 7 75 2.636e-07 3.254e-06
378 POSITIVE REGULATION OF CELL ADHESION 13 376 2.859e-07 3.52e-06
379 POSITIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 11 258 3.169e-07 3.876e-06
380 BONE DEVELOPMENT 9 156 3.174e-07 3.876e-06
381 REGULATION OF BMP SIGNALING PATHWAY 7 77 3.164e-07 3.876e-06
382 REGULATION OF CELL CELL ADHESION 13 380 3.225e-07 3.929e-06
383 NEURON PROJECTION GUIDANCE 10 205 3.263e-07 3.964e-06
384 DIGESTIVE TRACT MORPHOGENESIS 6 48 3.362e-07 4.074e-06
385 POSITIVE REGULATION OF NON CANONICAL WNT SIGNALING PATHWAY 4 11 3.436e-07 4.152e-06
386 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 8 115 3.543e-07 4.271e-06
387 NEGATIVE REGULATION OF CARTILAGE DEVELOPMENT 5 26 3.591e-07 4.318e-06
388 BONE MORPHOGENESIS 7 79 3.777e-07 4.53e-06
389 CARDIAC SEPTUM MORPHOGENESIS 6 49 3.813e-07 4.561e-06
390 REGENERATION 9 161 4.146e-07 4.934e-06
391 REGULATION OF DNA REPLICATION 9 161 4.146e-07 4.934e-06
392 CELL CELL SIGNALING 18 767 4.365e-07 5.181e-06
393 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 5 27 4.387e-07 5.194e-06
394 REGULATION OF JUN KINASE ACTIVITY 7 81 4.488e-07 5.3e-06
395 CELL CELL ADHESION 16 608 4.549e-07 5.359e-06
396 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 10 213 4.642e-07 5.454e-06
397 POSITIVE REGULATION OF FAT CELL DIFFERENTIATION 6 51 4.865e-07 5.702e-06
398 TAXIS 14 464 5.035e-07 5.887e-06
399 REGULATION OF MACROPHAGE CYTOKINE PRODUCTION 4 12 5.13e-07 5.983e-06
400 VENTRICULAR SEPTUM MORPHOGENESIS 5 28 5.316e-07 6.154e-06
401 DOPAMINERGIC NEURON DIFFERENTIATION 5 28 5.316e-07 6.154e-06
402 MAMMARY GLAND DUCT MORPHOGENESIS 5 28 5.316e-07 6.154e-06
403 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 8 122 5.577e-07 6.439e-06
404 POSITIVE REGULATION OF MITOCHONDRION ORGANIZATION 9 167 5.645e-07 6.502e-06
405 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 6 53 6.143e-07 7.04e-06
406 POSITIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 6 53 6.143e-07 7.04e-06
407 CARDIAC SEPTUM DEVELOPMENT 7 85 6.25e-07 7.146e-06
408 POSITIVE REGULATION OF BINDING 8 127 7.578e-07 8.643e-06
409 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 11 282 7.646e-07 8.699e-06
410 REGULATION OF KIDNEY DEVELOPMENT 6 55 7.685e-07 8.7e-06
411 CRANIAL SKELETAL SYSTEM DEVELOPMENT 6 55 7.685e-07 8.7e-06
412 REGULATION OF PHOSPHATASE ACTIVITY 8 128 8.045e-07 9.064e-06
413 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION 8 128 8.045e-07 9.064e-06
414 REGULATION OF CELL CYCLE PROCESS 15 558 8.236e-07 9.256e-06
415 GLIOGENESIS 9 175 8.361e-07 9.374e-06
416 CIRCADIAN REGULATION OF GENE EXPRESSION 6 57 9.529e-07 1.061e-05
417 REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 6 57 9.529e-07 1.061e-05
418 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 12 351 9.484e-07 1.061e-05
419 POSITIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 4 14 1.028e-06 1.142e-05
420 ENDOCARDIAL CUSHION DEVELOPMENT 5 32 1.069e-06 1.185e-05
421 ANGIOGENESIS 11 293 1.113e-06 1.23e-05
422 RESPONSE TO STEROID HORMONE 14 497 1.139e-06 1.255e-05
423 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 7 93 1.155e-06 1.27e-05
424 VASCULOGENESIS 6 59 1.172e-06 1.286e-05
425 NEURAL TUBE FORMATION 7 94 1.242e-06 1.359e-05
426 EMBRYONIC AXIS SPECIFICATION 5 33 1.255e-06 1.37e-05
427 RESPONSE TO EXTERNAL STIMULUS 28 1821 1.272e-06 1.385e-05
428 EYE MORPHOGENESIS 8 136 1.274e-06 1.385e-05
429 EPITHELIAL CELL DEVELOPMENT 9 186 1.39e-06 1.507e-05
430 EMBRYONIC DIGIT MORPHOGENESIS 6 61 1.431e-06 1.545e-05
431 POSITIVE REGULATION OF STEM CELL PROLIFERATION 6 61 1.431e-06 1.545e-05
432 REGULATION OF MESENCHYMAL CELL PROLIFERATION 5 34 1.464e-06 1.577e-05
433 POSITIVE REGULATION OF CELL CELL ADHESION 10 243 1.54e-06 1.655e-05
434 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 11 303 1.543e-06 1.655e-05
435 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 13 437 1.549e-06 1.656e-05
436 CARDIAC MUSCLE TISSUE DEVELOPMENT 8 140 1.586e-06 1.693e-05
437 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 7 98 1.647e-06 1.753e-05
438 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 9 191 1.731e-06 1.838e-05
439 POSITIVE REGULATION OF JUN KINASE ACTIVITY 6 63 1.734e-06 1.838e-05
440 ORGAN INDUCTION 4 16 1.853e-06 1.959e-05
441 BIOLOGICAL ADHESION 20 1032 1.871e-06 1.974e-05
442 CARDIAC CHAMBER DEVELOPMENT 8 144 1.96e-06 2.064e-05
443 HEAD MORPHOGENESIS 5 36 1.965e-06 2.064e-05
444 REGULATION OF ACTIN FILAMENT BASED PROCESS 11 312 2.05e-06 2.148e-05
445 RESPONSE TO ESTRADIOL 8 146 2.174e-06 2.273e-05
446 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 7 103 2.303e-06 2.402e-05
447 LEUKOCYTE CELL CELL ADHESION 10 255 2.375e-06 2.472e-05
448 PEPTIDYL SERINE MODIFICATION 8 148 2.407e-06 2.489e-05
449 NEGATIVE REGULATION OF STEM CELL PROLIFERATION 4 17 2.412e-06 2.489e-05
450 ESTABLISHMENT OF TISSUE POLARITY 4 17 2.412e-06 2.489e-05
451 NEGATIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 4 17 2.412e-06 2.489e-05
452 CARDIAC CHAMBER MORPHOGENESIS 7 104 2.457e-06 2.529e-05
453 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 6 68 2.729e-06 2.803e-05
454 REGULATION OF PEPTIDASE ACTIVITY 12 392 2.988e-06 3.062e-05
455 REGULATION OF PROTEIN CATABOLIC PROCESS 12 393 3.067e-06 3.136e-05
456 PERICARDIUM DEVELOPMENT 4 18 3.087e-06 3.143e-05
457 NOTOCHORD DEVELOPMENT 4 18 3.087e-06 3.143e-05
458 NEGATIVE REGULATION OF LOCOMOTION 10 263 3.129e-06 3.179e-05
459 AGING 10 264 3.237e-06 3.281e-05
460 NEGATIVE REGULATION OF HYDROLASE ACTIVITY 12 397 3.403e-06 3.442e-05
461 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 8 156 3.566e-06 3.599e-05
462 REGULATION OF NON CANONICAL WNT SIGNALING PATHWAY 4 19 3.893e-06 3.904e-05
463 ENTRAINMENT OF CIRCADIAN CLOCK BY PHOTOPERIOD 4 19 3.893e-06 3.904e-05
464 POSITIVE REGULATION OF CHONDROCYTE DIFFERENTIATION 4 19 3.893e-06 3.904e-05
465 SINGLE ORGANISM CELLULAR LOCALIZATION 18 898 4.108e-06 4.11e-05
466 POSITIVE REGULATION OF PROTEIN BINDING 6 73 4.146e-06 4.13e-05
467 PANCREAS DEVELOPMENT 6 73 4.146e-06 4.13e-05
468 OVULATION CYCLE 7 113 4.28e-06 4.255e-05
469 PITUITARY GLAND DEVELOPMENT 5 42 4.313e-06 4.27e-05
470 POSTTRANSCRIPTIONAL GENE SILENCING 5 42 4.313e-06 4.27e-05
471 NEPHRON DEVELOPMENT 7 115 4.809e-06 4.751e-05
472 BRANCHING INVOLVED IN MAMMARY GLAND DUCT MORPHOGENESIS 4 20 4.845e-06 4.766e-05
473 NEGATIVE REGULATION OF CHONDROCYTE DIFFERENTIATION 4 20 4.845e-06 4.766e-05
474 LYMPHOCYTE ACTIVATION 11 342 4.945e-06 4.854e-05
475 REGULATION OF MITOCHONDRION ORGANIZATION 9 218 5.118e-06 5.014e-05
476 LEUKOCYTE ACTIVATION 12 414 5.22e-06 5.102e-05
477 BODY MORPHOGENESIS 5 44 5.456e-06 5.322e-05
478 REGULATION OF EPITHELIAL CELL MIGRATION 8 166 5.65e-06 5.488e-05
479 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 8 166 5.65e-06 5.488e-05
480 DIENCEPHALON DEVELOPMENT 6 77 5.666e-06 5.493e-05
481 CELL AGGREGATION 4 21 5.958e-06 5.728e-05
482 POSITIVE REGULATION OF EXCITATORY POSTSYNAPTIC POTENTIAL 4 21 5.958e-06 5.728e-05
483 NEGATIVE REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 4 21 5.958e-06 5.728e-05
484 CARTILAGE CONDENSATION 4 21 5.958e-06 5.728e-05
485 ENDOCHONDRAL BONE MORPHOGENESIS 5 45 6.109e-06 5.849e-05
486 REGULATION OF ALCOHOL BIOSYNTHETIC PROCESS 5 45 6.109e-06 5.849e-05
487 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 5 46 6.823e-06 6.506e-05
488 EMBRYONIC CRANIAL SKELETON MORPHOGENESIS 5 46 6.823e-06 6.506e-05
489 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 7 122 7.111e-06 6.766e-05
490 MUSCLE STRUCTURE DEVELOPMENT 12 432 8.027e-06 7.622e-05
491 KIDNEY MORPHOGENESIS 6 82 8.174e-06 7.746e-05
492 POSITIVE REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 5 48 8.445e-06 7.986e-05
493 POSITIVE REGULATION OF PROTEOLYSIS 11 363 8.686e-06 8.198e-05
494 NEGATIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 4 23 8.736e-06 8.229e-05
495 MITOCHONDRIAL TRANSPORT 8 177 9.051e-06 8.508e-05
496 REGULATION OF STEROID BIOSYNTHETIC PROCESS 5 49 9.361e-06 8.782e-05
497 REGULATION OF CHEMOTAXIS 8 180 1.023e-05 9.581e-05
498 TUBE FORMATION 7 129 1.026e-05 9.589e-05
499 FACE DEVELOPMENT 5 50 1.035e-05 9.654e-05
500 PHOTOPERIODISM 4 24 1.044e-05 9.693e-05
501 RESPONSE TO STEROL 4 24 1.044e-05 9.693e-05
502 PROTEIN STABILIZATION 7 131 1.135e-05 0.0001052
503 MAINTENANCE OF CELL NUMBER 7 132 1.193e-05 0.0001104
504 OVULATION CYCLE PROCESS 6 88 1.23e-05 0.0001135
505 POSITIVE REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION 4 25 1.237e-05 0.000114
506 POSITIVE REGULATION OF DNA METABOLIC PROCESS 8 185 1.249e-05 0.0001149
507 EPITHELIAL CELL PROLIFERATION 6 89 1.313e-05 0.0001205
508 POSITIVE REGULATION OF CELL CYCLE PROCESS 9 247 1.397e-05 0.0001279
509 ENDOTHELIUM DEVELOPMENT 6 90 1.4e-05 0.0001279
510 NEGATIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 7 136 1.449e-05 0.000132
511 ENTRAINMENT OF CIRCADIAN CLOCK 4 26 1.455e-05 0.000132
512 NEGATIVE REGULATION OF EMBRYONIC DEVELOPMENT 4 26 1.455e-05 0.000132
513 REGULATION OF HORMONE METABOLIC PROCESS 4 26 1.455e-05 0.000132
514 VENTRICULAR SEPTUM DEVELOPMENT 5 54 1.517e-05 0.0001373
515 INNER EAR MORPHOGENESIS 6 92 1.588e-05 0.0001435
516 REGULATION OF MITOTIC CELL CYCLE 12 468 1.783e-05 0.0001608
517 MORPHOGENESIS OF A POLARIZED EPITHELIUM 4 28 1.975e-05 0.0001778
518 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 8 199 2.117e-05 0.0001902
519 REGULATION OF CELL PROJECTION ORGANIZATION 13 558 2.152e-05 0.0001922
520 REGULATION OF CATABOLIC PROCESS 15 731 2.149e-05 0.0001922
521 REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 6 97 2.15e-05 0.0001922
522 SYNAPSE ORGANIZATION 7 145 2.196e-05 0.0001954
523 NEGATIVE REGULATION OF MAPK CASCADE 7 145 2.196e-05 0.0001954
524 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 4 29 2.281e-05 0.0002018
525 NEUROBLAST PROLIFERATION 4 29 2.281e-05 0.0002018
526 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 6 98 2.279e-05 0.0002018
527 POSITIVE REGULATION OF PROTEIN CATABOLIC PROCESS 9 263 2.296e-05 0.0002027
528 POSITIVE REGULATION OF CELL GROWTH 7 148 2.507e-05 0.0002209
529 MODULATION OF EXCITATORY POSTSYNAPTIC POTENTIAL 4 30 2.62e-05 0.0002305
530 CAMERA TYPE EYE MORPHOGENESIS 6 101 2.705e-05 0.0002371
531 REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 6 101 2.705e-05 0.0002371
532 REGULATION OF CELL DIVISION 9 272 2.99e-05 0.0002615
533 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 8 209 3.008e-05 0.0002621
534 LYMPHOCYTE DIFFERENTIATION 8 209 3.008e-05 0.0002621
535 MUSCLE TISSUE DEVELOPMENT 9 275 3.258e-05 0.0002833
536 SALIVARY GLAND DEVELOPMENT 4 32 3.408e-05 0.0002953
537 POSITIVE REGULATION OF BMP SIGNALING PATHWAY 4 32 3.408e-05 0.0002953
538 FAT CELL DIFFERENTIATION 6 106 3.557e-05 0.0003076
539 RESPONSE TO NITROGEN COMPOUND 16 859 3.632e-05 0.0003136
540 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 8 216 3.803e-05 0.0003277
541 EMBRYONIC DIGESTIVE TRACT DEVELOPMENT 4 33 3.86e-05 0.0003314
542 POSITIVE REGULATION OF EMBRYONIC DEVELOPMENT 4 33 3.86e-05 0.0003314
543 NEGATIVE REGULATION OF CARDIAC MUSCLE TISSUE GROWTH 3 12 4.026e-05 0.0003431
544 ANATOMICAL STRUCTURE REGRESSION 3 12 4.026e-05 0.0003431
545 NEGATIVE REGULATION OF HEART GROWTH 3 12 4.026e-05 0.0003431
546 LENS FIBER CELL DEVELOPMENT 3 12 4.026e-05 0.0003431
547 SOMATIC STEM CELL POPULATION MAINTENANCE 5 66 4.056e-05 0.0003446
548 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 16 867 4.059e-05 0.0003446
549 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 5 67 4.363e-05 0.0003671
550 ORGAN FORMATION 4 34 4.356e-05 0.0003671
551 PROTEIN DESTABILIZATION 4 34 4.356e-05 0.0003671
552 NEURON FATE COMMITMENT 5 67 4.363e-05 0.0003671
553 BRAIN MORPHOGENESIS 4 34 4.356e-05 0.0003671
554 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 6 111 4.612e-05 0.0003873
555 NEGATIVE REGULATION OF CELL ADHESION 8 223 4.766e-05 0.0003995
556 EAR MORPHOGENESIS 6 112 4.85e-05 0.0004059
557 SYNAPSE ASSEMBLY 5 69 5.031e-05 0.0004203
558 NEURONAL STEM CELL DIVISION 3 13 5.212e-05 0.00043
559 TYPE B PANCREATIC CELL DEVELOPMENT 3 13 5.212e-05 0.00043
560 LEUKOCYTE DIFFERENTIATION 9 292 5.191e-05 0.00043
561 HEMATOPOIETIC STEM CELL PROLIFERATION 3 13 5.212e-05 0.00043
562 GDP METABOLIC PROCESS 3 13 5.212e-05 0.00043
563 NEUROBLAST DIVISION 3 13 5.212e-05 0.00043
564 REGULATION OF CELL FATE SPECIFICATION 3 13 5.212e-05 0.00043
565 REGULATION OF ENDOTHELIAL CELL MIGRATION 6 114 5.356e-05 0.0004411
566 MUSCLE ORGAN MORPHOGENESIS 5 70 5.393e-05 0.0004433
567 TELENCEPHALON DEVELOPMENT 8 228 5.572e-05 0.0004572
568 SKIN EPIDERMIS DEVELOPMENT 5 71 5.775e-05 0.0004731
569 NEGATIVE REGULATION OF EPITHELIAL CELL DIFFERENTIATION 4 37 6.12e-05 0.0005005
570 ENERGY RESERVE METABOLIC PROCESS 5 72 6.177e-05 0.0005034
571 ENDOTHELIAL CELL DIFFERENTIATION 5 72 6.177e-05 0.0005034
572 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 8 232 6.296e-05 0.0005121
573 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 6 118 6.494e-05 0.0005264
574 REGULATION OF VASCULATURE DEVELOPMENT 8 233 6.488e-05 0.0005264
575 NEGATIVE REGULATION OF MAP KINASE ACTIVITY 5 73 6.601e-05 0.0005308
576 REGULATION OF ESTABLISHMENT OF PLANAR POLARITY INVOLVED IN NEURAL TUBE CLOSURE 3 14 6.605e-05 0.0005308
577 EMBRYONIC HEART TUBE DEVELOPMENT 5 73 6.601e-05 0.0005308
578 HIPPOCAMPUS DEVELOPMENT 5 73 6.601e-05 0.0005308
579 RESPONSE TO LAMINAR FLUID SHEAR STRESS 3 14 6.605e-05 0.0005308
580 POSITIVE REGULATION OF HYDROLASE ACTIVITY 16 905 6.751e-05 0.0005416
581 REGULATION OF CELL SUBSTRATE ADHESION 7 173 6.778e-05 0.0005428
582 REGULATION OF STEROID METABOLIC PROCESS 5 74 7.047e-05 0.0005634
583 NEGATIVE REGULATION OF TRANSPORT 11 458 7.304e-05 0.000583
584 NEURAL CREST CELL DIFFERENTIATION 5 75 7.515e-05 0.0005988
585 NEGATIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 4 39 7.554e-05 0.0005988
586 REGULATION OF AXON GUIDANCE 4 39 7.554e-05 0.0005988
587 GLANDULAR EPITHELIAL CELL DIFFERENTIATION 4 39 7.554e-05 0.0005988
588 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 14 724 7.807e-05 0.0006176
589 LOCALIZATION WITHIN MEMBRANE 6 122 7.818e-05 0.0006176
590 REGULATION OF HAIR FOLLICLE DEVELOPMENT 3 15 8.221e-05 0.000644
591 ENDOCARDIAL CUSHION FORMATION 3 15 8.221e-05 0.000644
592 REGULATION OF MESODERM DEVELOPMENT 3 15 8.221e-05 0.000644
593 POSITIVE REGULATION OF T CELL APOPTOTIC PROCESS 3 15 8.221e-05 0.000644
594 T CELL DIFFERENTIATION 6 123 8.181e-05 0.000644
595 NEGATIVE REGULATION OF DEPHOSPHORYLATION 5 77 8.524e-05 0.0006655
596 REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 5 77 8.524e-05 0.0006655
597 REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS 7 181 9.004e-05 0.0007017
598 RENAL TUBULE DEVELOPMENT 5 78 9.066e-05 0.0007054
599 LUNG ALVEOLUS DEVELOPMENT 4 41 9.218e-05 0.0007149
600 RECEPTOR CLUSTERING 4 41 9.218e-05 0.0007149
601 MACROMOLECULAR COMPLEX DISASSEMBLY 7 182 9.32e-05 0.0007215
602 NEGATIVE REGULATION OF PROTEIN BINDING 5 79 9.634e-05 0.0007447
603 PROTEIN LOCALIZATION TO SYNAPSE 3 16 0.0001008 0.0007775
604 REGULATION OF HEART GROWTH 4 42 0.0001014 0.0007801
605 GENITALIA DEVELOPMENT 4 42 0.0001014 0.0007801
606 REGULATION OF CYTOKINE PRODUCTION 12 563 0.0001059 0.0008134
607 REGULATION OF POLYSACCHARIDE METABOLIC PROCESS 4 43 0.0001113 0.0008535
608 POSITIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 6 131 0.0001159 0.0008854
609 NEGATIVE REGULATION OF BINDING 6 131 0.0001159 0.0008854
610 LABYRINTHINE LAYER DEVELOPMENT 4 44 0.0001219 0.0009136
611 HAIR CYCLE 5 83 0.0001219 0.0009136
612 NEGATIVE REGULATION OF ALCOHOL BIOSYNTHETIC PROCESS 3 17 0.0001218 0.0009136
613 EMBRYONIC PLACENTA DEVELOPMENT 5 83 0.0001219 0.0009136
614 POSITIVE REGULATION OF CELL DIVISION 6 132 0.0001208 0.0009136
615 POSITIVE REGULATION OF EXTRACELLULAR MATRIX ORGANIZATION 3 17 0.0001218 0.0009136
616 BRANCHING INVOLVED IN URETERIC BUD MORPHOGENESIS 4 44 0.0001219 0.0009136
617 MOLTING CYCLE 5 83 0.0001219 0.0009136
618 REGULATION OF STEM CELL POPULATION MAINTENANCE 3 17 0.0001218 0.0009136
619 MAMMARY GLAND ALVEOLUS DEVELOPMENT 3 17 0.0001218 0.0009136
620 PROTEIN DEPHOSPHORYLATION 7 190 0.0001219 0.0009136
621 MAMMARY GLAND LOBULE DEVELOPMENT 3 17 0.0001218 0.0009136
622 PROTEIN TARGETING 10 406 0.0001282 0.0009589
623 LUNG MORPHOGENESIS 4 45 0.0001332 0.0009932
624 EXOCRINE SYSTEM DEVELOPMENT 4 45 0.0001332 0.0009932
625 REGULATION OF NEURON PROJECTION DEVELOPMENT 10 408 0.0001334 0.0009932
626 GLIAL CELL DIFFERENTIATION 6 136 0.0001423 0.001058
627 POSITIVE REGULATION OF DNA REPLICATION 5 86 0.0001442 0.00107
628 GLANDULAR EPITHELIAL CELL DEVELOPMENT 3 18 0.0001456 0.001072
629 REGULATION OF HORMONE BIOSYNTHETIC PROCESS 3 18 0.0001456 0.001072
630 OSTEOBLAST DEVELOPMENT 3 18 0.0001456 0.001072
631 POST ANAL TAIL MORPHOGENESIS 3 18 0.0001456 0.001072
632 UTERUS DEVELOPMENT 3 18 0.0001456 0.001072
633 RESPONSE TO RADIATION 10 413 0.0001473 0.001083
634 IMMUNE SYSTEM PROCESS 25 1984 0.0001498 0.001099
635 PLACENTA DEVELOPMENT 6 138 0.0001542 0.00113
636 REGULATION OF IMMUNE SYSTEM PROCESS 20 1403 0.0001554 0.001137
637 POSITIVE REGULATION OF GLIOGENESIS 4 47 0.0001581 0.001155
638 SECRETION 12 588 0.0001589 0.001159
639 POSITIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 5 88 0.0001607 0.00117
640 NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 7 200 0.0001673 0.001217
641 REGULATION OF CARDIAC MUSCLE CELL DIFFERENTIATION 3 19 0.0001721 0.001245
642 CELLULAR RESPONSE TO NITROGEN COMPOUND 11 505 0.0001724 0.001245
643 ENTEROENDOCRINE CELL DIFFERENTIATION 3 19 0.0001721 0.001245
644 ANTERIOR POSTERIOR AXIS SPECIFICATION 4 48 0.0001717 0.001245
645 REGULATION OF CELL MATRIX ADHESION 5 90 0.0001786 0.001286
646 REGULATION OF GLIOGENESIS 5 90 0.0001786 0.001286
647 EPIDERMAL CELL DIFFERENTIATION 6 142 0.0001802 0.001296
648 POSITIVE REGULATION OF LYMPHOCYTE APOPTOTIC PROCESS 3 20 0.0002017 0.001441
649 TONGUE DEVELOPMENT 3 20 0.0002017 0.001441
650 TRACHEA DEVELOPMENT 3 20 0.0002017 0.001441
651 GMP METABOLIC PROCESS 3 20 0.0002017 0.001441
652 NEPHRON EPITHELIUM DEVELOPMENT 5 93 0.0002083 0.001482
653 REGULATION OF DNA BINDING 5 93 0.0002083 0.001482
654 RESPONSE TO DRUG 10 431 0.0002078 0.001482
655 HOMOTYPIC CELL CELL ADHESION 4 51 0.0002176 0.001545
656 ACTIVATION OF PROTEIN KINASE ACTIVITY 8 279 0.0002245 0.001593
657 REGULATION OF PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 6 148 0.0002255 0.001597
658 POSITIVE REGULATION OF PROTEIN SECRETION 7 211 0.0002323 0.001643
659 REGULATION OF GENE SILENCING BY RNA 3 21 0.0002343 0.001647
660 CHONDROCYTE DEVELOPMENT 3 21 0.0002343 0.001647
661 TISSUE REGENERATION 4 52 0.0002346 0.001647
662 COCHLEA MORPHOGENESIS 3 21 0.0002343 0.001647
663 REGULATION OF POSTTRANSCRIPTIONAL GENE SILENCING 3 21 0.0002343 0.001647
664 CELLULAR RESPONSE TO STRESS 21 1565 0.00024 0.001682
665 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 7 213 0.0002461 0.001722
666 POSITIVE REGULATION OF FIBROBLAST PROLIFERATION 4 53 0.0002527 0.00176
667 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 4 53 0.0002527 0.00176
668 MESONEPHRIC TUBULE MORPHOGENESIS 4 53 0.0002527 0.00176
669 NEGATIVE REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 3 22 0.0002701 0.001868
670 REGULATION OF HAIR CYCLE 3 22 0.0002701 0.001868
671 DSRNA FRAGMENTATION 3 22 0.0002701 0.001868
672 EMBRYONIC PLACENTA MORPHOGENESIS 3 22 0.0002701 0.001868
673 PRODUCTION OF SMALL RNA INVOLVED IN GENE SILENCING BY RNA 3 22 0.0002701 0.001868
674 CARDIAC MUSCLE TISSUE MORPHOGENESIS 4 54 0.0002717 0.001875
675 AMEBOIDAL TYPE CELL MIGRATION 6 154 0.0002795 0.001926
676 POSTTRANSCRIPTIONAL REGULATION OF GENE EXPRESSION 10 448 0.0002831 0.001948
677 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 4 55 0.0002917 0.002005
678 LIMBIC SYSTEM DEVELOPMENT 5 100 0.0002922 0.002005
679 KERATINOCYTE DIFFERENTIATION 5 101 0.000306 0.002094
680 REGULATION OF EXTENT OF CELL GROWTH 5 101 0.000306 0.002094
681 ESTABLISHMENT OF EPITHELIAL CELL POLARITY 3 23 0.0003094 0.002101
682 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 3 23 0.0003094 0.002101
683 SCF DEPENDENT PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 3 23 0.0003094 0.002101
684 REGULATION OF METANEPHROS DEVELOPMENT 3 23 0.0003094 0.002101
685 POSITIVE REGULATION OF COLLAGEN METABOLIC PROCESS 3 23 0.0003094 0.002101
686 ENDOTHELIAL CELL MIGRATION 4 57 0.0003348 0.002271
687 PROTEIN LOCALIZATION TO MEMBRANE 9 376 0.0003468 0.002349
688 NEGATIVE REGULATION OF STEROID METABOLIC PROCESS 3 24 0.0003521 0.002371
689 EMBRYONIC CAMERA TYPE EYE MORPHOGENESIS 3 24 0.0003521 0.002371
690 REGULATION OF ODONTOGENESIS 3 24 0.0003521 0.002371
691 REGULATION OF PROTEIN PHOSPHATASE TYPE 2A ACTIVITY 3 24 0.0003521 0.002371
692 CELLULAR GLUCAN METABOLIC PROCESS 4 58 0.000358 0.002404
693 GLUCAN METABOLIC PROCESS 4 58 0.000358 0.002404
694 POSITIVE REGULATION OF HEMOPOIESIS 6 163 0.0003788 0.00254
695 REGULATION OF GENE EXPRESSION EPIGENETIC 7 229 0.0003814 0.002554
696 CARDIAC VENTRICLE DEVELOPMENT 5 106 0.0003826 0.002558
697 FOREBRAIN REGIONALIZATION 3 25 0.0003984 0.002652
698 REGULATION OF TRANSFORMING GROWTH FACTOR BETA PRODUCTION 3 25 0.0003984 0.002652
699 EPITHELIAL CELL APOPTOTIC PROCESS 3 25 0.0003984 0.002652
700 REGULATION OF LEUKOCYTE DIFFERENTIATION 7 232 0.0004124 0.002741
701 REGULATION OF CELL CYCLE ARREST 5 108 0.000417 0.002768
702 REGULATION OF PROTEIN SECRETION 9 389 0.0004439 0.002942
703 REGULATION OF AXONOGENESIS 6 168 0.0004449 0.002944
704 REGULATION OF CELL FATE COMMITMENT 3 26 0.0004484 0.002964
705 REGULATION OF SMOOTHENED SIGNALING PATHWAY 4 62 0.0004624 0.003048
706 EMBRYONIC HEART TUBE MORPHOGENESIS 4 62 0.0004624 0.003048
707 MUSCLE CELL DIFFERENTIATION 7 237 0.0004685 0.003083
708 POSITIVE REGULATION OF CATABOLIC PROCESS 9 395 0.0004957 0.003258
709 SKELETAL MUSCLE TISSUE REGENERATION 3 27 0.0005024 0.003283
710 NEGATIVE REGULATION OF AXON GUIDANCE 3 27 0.0005024 0.003283
711 RESPONSE TO LITHIUM ION 3 27 0.0005024 0.003283
712 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER INVOLVED IN CELLULAR RESPONSE TO CHEMICAL STIMULUS 3 27 0.0005024 0.003283
713 REGULATION OF CELL SIZE 6 172 0.0005039 0.003288
714 STRIATED MUSCLE CELL DIFFERENTIATION 6 173 0.0005195 0.003386
715 POSITIVE REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 4 64 0.000522 0.003397
716 NOTCH SIGNALING PATHWAY 5 114 0.0005343 0.003472
717 SECRETION BY CELL 10 486 0.0005362 0.003479
718 REGULATION OF MICROTUBULE BASED PROCESS 7 243 0.0005437 0.003523
719 POSITIVE REGULATION OF LEUKOCYTE APOPTOTIC PROCESS 3 28 0.0005603 0.003611
720 GASTRULATION WITH MOUTH FORMING SECOND 3 28 0.0005603 0.003611
721 CELL FATE COMMITMENT INVOLVED IN FORMATION OF PRIMARY GERM LAYER 3 28 0.0005603 0.003611
722 REGULATION OF NEUROBLAST PROLIFERATION 3 28 0.0005603 0.003611
723 RESPONSE TO CORTICOSTEROID 6 176 0.0005688 0.003661
724 REGULATION OF CELL CYCLE PHASE TRANSITION 8 321 0.0005716 0.003674
725 FEMALE SEX DIFFERENTIATION 5 116 0.0005784 0.003712
726 RESPONSE TO PEPTIDE 9 404 0.0005826 0.003734
727 ESTABLISHMENT OF LOCALIZATION IN CELL 21 1676 0.0005991 0.003834
728 NEGATIVE REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 3 29 0.0006223 0.003966
729 REGULATION OF EXTRACELLULAR MATRIX ORGANIZATION 3 29 0.0006223 0.003966
730 POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 3 29 0.0006223 0.003966
731 ORGAN GROWTH 4 68 0.0006573 0.004178
732 POSITIVE REGULATION OF CELL CYCLE PHASE TRANSITION 4 68 0.0006573 0.004178
733 POSITIVE REGULATION OF CHEMOTAXIS 5 120 0.0006748 0.004284
734 POSITIVE REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 3 30 0.0006885 0.004365
735 POSITIVE REGULATION OF AXONOGENESIS 4 69 0.0006946 0.004397
736 ORGANELLE LOCALIZATION 9 415 0.0007054 0.00446
737 REGULATION OF SYSTEM PROCESS 10 507 0.0007425 0.004688
738 CELL FATE SPECIFICATION 4 71 0.0007738 0.004879
739 REGULATION OF CELLULAR COMPONENT SIZE 8 337 0.0007848 0.004941
740 NEGATIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 3 32 0.0008341 0.00523
741 POSITIVE REGULATION OF GLIAL CELL DIFFERENTIATION 3 32 0.0008341 0.00523
742 EMBRYONIC FORELIMB MORPHOGENESIS 3 32 0.0008341 0.00523
743 REGULATION OF PLASMA MEMBRANE ORGANIZATION 4 73 0.0008591 0.00538
744 CELLULAR RESPONSE TO ABIOTIC STIMULUS 7 263 0.0008662 0.005417
745 REGULATION OF NEURON APOPTOTIC PROCESS 6 192 0.0008962 0.005597
746 REGULATION OF LIPID BIOSYNTHETIC PROCESS 5 128 0.0009031 0.005633
747 REGULATION OF T CELL APOPTOTIC PROCESS 3 33 0.0009136 0.005676
748 RESPONSE TO VITAMIN D 3 33 0.0009136 0.005676
749 EMBRYONIC EYE MORPHOGENESIS 3 33 0.0009136 0.005676
750 CELL CYCLE CHECKPOINT 6 194 0.0009456 0.005866
751 LUNG EPITHELIUM DEVELOPMENT 3 34 0.0009978 0.006166
752 RESPONSE TO FLUID SHEAR STRESS 3 34 0.0009978 0.006166
753 HEART VALVE DEVELOPMENT 3 34 0.0009978 0.006166
754 GLIAL CELL DEVELOPMENT 4 76 0.0009993 0.006167
755 NEGATIVE REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 5 131 0.001002 0.006175
756 POSITIVE REGULATION OF NF KAPPAB TRANSCRIPTION FACTOR ACTIVITY 5 132 0.001037 0.006372
757 REGULATION OF LYMPHOCYTE DIFFERENTIATION 5 132 0.001037 0.006372
758 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 5 133 0.001072 0.006582
759 REGULATION OF GLYCOGEN METABOLIC PROCESS 3 35 0.001087 0.006636
760 REGULATION OF GASTRULATION 3 35 0.001087 0.006636
761 EMBRYONIC CAMERA TYPE EYE DEVELOPMENT 3 35 0.001087 0.006636
762 RESPONSE TO IRON ION 3 35 0.001087 0.006636
763 REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 7 274 0.001099 0.006702
764 CELL GROWTH 5 135 0.001146 0.00698
765 CYTOSKELETON ORGANIZATION 13 838 0.001148 0.006984
766 MUSCLE ORGAN DEVELOPMENT 7 277 0.00117 0.007109
767 POSITIVE REGULATION OF PROTEIN ACETYLATION 3 36 0.001181 0.007144
768 REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 3 36 0.001181 0.007144
769 POSITIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 3 36 0.001181 0.007144
770 POLYSACCHARIDE METABOLIC PROCESS 4 80 0.00121 0.007304
771 POSITIVE REGULATION OF LYMPHOCYTE DIFFERENTIATION 4 80 0.00121 0.007304
772 HINDBRAIN DEVELOPMENT 5 137 0.001224 0.007375
773 ACTIN FILAMENT BASED PROCESS 9 450 0.001244 0.007486
774 RESPONSE TO LIGHT STIMULUS 7 280 0.001245 0.007486
775 METANEPHROS DEVELOPMENT 4 81 0.001267 0.00758
776 NEGATIVE REGULATION OF CELL CELL ADHESION 5 138 0.001264 0.00758
777 REGULATION OF FIBROBLAST PROLIFERATION 4 81 0.001267 0.00758
778 POSITIVE REGULATION OF PROTEIN KINASE B SIGNALING 4 81 0.001267 0.00758
779 HINDLIMB MORPHOGENESIS 3 37 0.001279 0.007632
780 RESPONSE TO NERVE GROWTH FACTOR 3 37 0.001279 0.007632
781 REGULATION OF LIPID METABOLIC PROCESS 7 282 0.001297 0.007729
782 MITOTIC CELL CYCLE CHECKPOINT 5 139 0.001305 0.007755
783 GENE SILENCING BY RNA 5 139 0.001305 0.007755
784 NEGATIVE REGULATION OF AXON EXTENSION 3 38 0.001383 0.008188
785 CELLULAR RESPONSE TO DSRNA 3 38 0.001383 0.008188
786 REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 3 38 0.001383 0.008188
787 ORGAN REGENERATION 4 83 0.001388 0.008203
788 DEPHOSPHORYLATION 7 286 0.001406 0.008304
789 CELLULAR RESPONSE TO HORMONE STIMULUS 10 552 0.001409 0.008311
790 POSITIVE REGULATION OF SECRETION 8 370 0.001426 0.008402
791 PLATELET ACTIVATION 5 142 0.001435 0.008438
792 TISSUE MIGRATION 4 84 0.00145 0.008521
793 NEGATIVE REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 3 39 0.001492 0.008722
794 REGULATION OF CELL ADHESION MEDIATED BY INTEGRIN 3 39 0.001492 0.008722
795 COCHLEA DEVELOPMENT 3 39 0.001492 0.008722
796 PLATELET AGGREGATION 3 39 0.001492 0.008722
797 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 5 144 0.001526 0.008909
798 RESPONSE TO IONIZING RADIATION 5 145 0.001573 0.009173
799 FORELIMB MORPHOGENESIS 3 40 0.001606 0.009331
800 POSITIVE REGULATION OF CELL MATRIX ADHESION 3 40 0.001606 0.009331
801 ENDOCRINE PANCREAS DEVELOPMENT 3 40 0.001606 0.009331
802 POSITIVE REGULATION OF IMMUNE RESPONSE 10 563 0.001631 0.009461
803 TISSUE REMODELING 4 87 0.001651 0.009556
804 REGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS 4 87 0.001651 0.009556
805 MULTICELLULAR ORGANISM REPRODUCTION 12 768 0.001682 0.009722
806 NEGATIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 4 88 0.001722 0.009942
807 POSITIVE REGULATION OF KIDNEY DEVELOPMENT 3 41 0.001726 0.009951
NumGOOverlapSizeP ValueAdj. P Value
1 FRIZZLED BINDING 14 36 7.395e-23 6.87e-20
2 TRANSFORMING GROWTH FACTOR BETA RECEPTOR BINDING 14 50 1.709e-20 7.937e-18
3 RECEPTOR BINDING 42 1476 5.57e-19 1.725e-16
4 BETA CATENIN BINDING 15 84 1.178e-18 2.736e-16
5 ENZYME BINDING 44 1737 5.003e-18 9.295e-16
6 WNT ACTIVATED RECEPTOR ACTIVITY 9 22 2.529e-15 3.915e-13
7 KINASE BINDING 25 606 8.174e-15 1.085e-12
8 PROTEIN DOMAIN SPECIFIC BINDING 25 624 1.59e-14 1.846e-12
9 WNT PROTEIN BINDING 9 31 9.813e-14 1.013e-11
10 SMAD BINDING 11 72 3.459e-13 3.213e-11
11 I SMAD BINDING 6 11 1.507e-11 1.273e-09
12 G PROTEIN COUPLED RECEPTOR BINDING 15 259 2.765e-11 2.141e-09
13 GROWTH FACTOR ACTIVITY 12 160 1.522e-10 1.088e-08
14 RECEPTOR AGONIST ACTIVITY 6 16 2.552e-10 1.693e-08
15 RECEPTOR SIGNALING PROTEIN ACTIVITY 12 172 3.527e-10 2.184e-08
16 CYTOKINE ACTIVITY 13 219 4.644e-10 2.696e-08
17 CYTOKINE RECEPTOR BINDING 14 271 5.936e-10 3.244e-08
18 PROTEIN DIMERIZATION ACTIVITY 26 1149 1.608e-09 8.3e-08
19 PDZ DOMAIN BINDING 9 90 2.586e-09 1.264e-07
20 UBIQUITIN LIKE PROTEIN LIGASE BINDING 13 264 4.519e-09 2.041e-07
21 GAMMA CATENIN BINDING 5 12 4.614e-09 2.041e-07
22 PROTEIN HETERODIMERIZATION ACTIVITY 16 468 1.272e-08 5.372e-07
23 MACROMOLECULAR COMPLEX BINDING 27 1399 2.193e-08 8.857e-07
24 RECEPTOR ACTIVATOR ACTIVITY 6 32 2.677e-08 1.036e-06
25 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE ACTIVITY 5 17 3.522e-08 1.309e-06
26 MOLECULAR FUNCTION REGULATOR 26 1353 4.626e-08 1.592e-06
27 PROTEIN SERINE THREONINE KINASE ACTIVITY 15 445 4.533e-08 1.592e-06
28 KINASE ACTIVITY 20 842 7.538e-08 2.501e-06
29 PROTEIN COMPLEX BINDING 21 935 8.769e-08 2.809e-06
30 SIGNAL TRANSDUCER ACTIVITY 29 1731 1.286e-07 3.982e-06
31 PROTEIN KINASE ACTIVITY 17 640 1.681e-07 5.038e-06
32 RECEPTOR REGULATOR ACTIVITY 6 45 2.263e-07 6.571e-06
33 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 20 992 1.018e-06 2.867e-05
34 RECEPTOR SIGNALING PROTEIN SERINE THREONINE KINASE ACTIVITY 7 92 1.073e-06 2.932e-05
35 PROTEIN C TERMINUS BINDING 9 186 1.39e-06 3.602e-05
36 RECEPTOR SERINE THREONINE KINASE BINDING 4 15 1.396e-06 3.602e-05
37 TRANSCRIPTION FACTOR BINDING 14 524 2.116e-06 5.314e-05
38 REGULATORY REGION NUCLEIC ACID BINDING 17 818 4.869e-06 0.000119
39 IONOTROPIC GLUTAMATE RECEPTOR BINDING 4 23 8.736e-06 0.0002081
40 CORE PROMOTER PROXIMAL REGION DNA BINDING 11 371 1.066e-05 0.0002475
41 IDENTICAL PROTEIN BINDING 20 1209 1.962e-05 0.0004446
42 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 10 328 2.154e-05 0.0004765
43 GLYCOPROTEIN BINDING 6 101 2.705e-05 0.0005845
44 GUANYLATE KINASE ACTIVITY 3 12 4.026e-05 0.0008311
45 CO SMAD BINDING 3 12 4.026e-05 0.0008311
46 PHOSPHATASE BINDING 7 162 4.471e-05 0.000903
47 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 8 226 5.237e-05 0.001014
48 ARMADILLO REPEAT DOMAIN BINDING 3 13 5.212e-05 0.001014
49 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 19 1199 5.825e-05 0.001104
50 GLUTAMATE RECEPTOR BINDING 4 37 6.12e-05 0.001137
51 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 13 629 7.356e-05 0.00134
52 PROTEIN HOMODIMERIZATION ACTIVITY 14 722 7.581e-05 0.001354
53 TRANSFORMING GROWTH FACTOR BETA BINDING 3 16 0.0001008 0.001766
54 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 5 81 0.0001085 0.001833
55 CELL ADHESION MOLECULE BINDING 7 186 0.0001067 0.001833
56 ENZYME REGULATOR ACTIVITY 16 959 0.0001324 0.002197
57 CYTOKINE BINDING 5 92 0.000198 0.003227
58 PROTEIN PHOSPHATASE TYPE 2A REGULATOR ACTIVITY 3 21 0.0002343 0.003753
59 R SMAD BINDING 3 23 0.0003094 0.004871
60 PROTEIN N TERMINUS BINDING 5 103 0.0003351 0.005189
61 PROTEIN PHOSPHORYLATED AMINO ACID BINDING 3 24 0.0003521 0.005191
62 NUCLEOTIDE KINASE ACTIVITY 3 24 0.0003521 0.005191
63 RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 5 104 0.0003504 0.005191
64 PHOSPHOPROTEIN BINDING 4 60 0.0004078 0.00592
65 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 8 315 0.000505 0.007217
66 PROTEIN SERINE THREONINE PHOSPHATASE ACTIVITY 4 64 0.000522 0.007348
67 CADHERIN BINDING 3 28 0.0005603 0.007769
68 PROTEIN PHOSPHATASE BINDING 5 120 0.0006748 0.009219
NumGOOverlapSizeP ValueAdj. P Value
1 CELL JUNCTION 35 1151 1.497e-16 8.742e-14
2 APICAL JUNCTION COMPLEX 15 128 8.527e-16 2.49e-13
3 CELL CELL JUNCTION 18 383 8.189e-12 1.594e-09
4 WNT SIGNALOSOME 6 11 1.507e-11 2.201e-09
5 EXTRACELLULAR MATRIX 18 426 4.731e-11 5.526e-09
6 CELL SURFACE 23 757 5.793e-11 5.639e-09
7 CYTOPLASMIC VESICLE PART 20 601 2.516e-10 2.099e-08
8 PHOSPHATASE COMPLEX 8 48 3.119e-10 2.277e-08
9 ANCHORING JUNCTION 18 489 4.411e-10 2.862e-08
10 EXTRACELLULAR SPACE 29 1376 7.713e-10 4.504e-08
11 CELL CORTEX 12 238 1.411e-08 7.493e-07
12 TRANSCRIPTION FACTOR COMPLEX 13 298 1.918e-08 8.771e-07
13 PROTEINACEOUS EXTRACELLULAR MATRIX 14 356 1.952e-08 8.771e-07
14 VESICLE MEMBRANE 16 512 4.439e-08 1.82e-06
15 CYTOSKELETON 32 1967 4.675e-08 1.82e-06
16 PROTEIN PHOSPHATASE TYPE 2A COMPLEX 5 20 8.703e-08 3.177e-06
17 NEURON PROJECTION 21 942 9.94e-08 3.415e-06
18 CYTOPLASMIC REGION 12 287 1.106e-07 3.587e-06
19 CELL BODY 15 494 1.758e-07 5.404e-06
20 INTRACELLULAR VESICLE 24 1259 1.961e-07 5.727e-06
21 NEURON PART 24 1265 2.14e-07 5.951e-06
22 ENDOCYTIC VESICLE MEMBRANE 9 152 2.545e-07 6.713e-06
23 PLASMA MEMBRANE PROTEIN COMPLEX 15 510 2.644e-07 6.713e-06
24 CELL SUBSTRATE JUNCTION 13 398 5.448e-07 1.326e-05
25 PLASMA MEMBRANE RECEPTOR COMPLEX 9 175 8.361e-07 1.941e-05
26 CELL PROJECTION 28 1786 8.641e-07 1.941e-05
27 BETA CATENIN DESTRUCTION COMPLEX 4 14 1.028e-06 2.224e-05
28 SOMATODENDRITIC COMPARTMENT 16 650 1.097e-06 2.288e-05
29 GOLGI LUMEN 7 94 1.242e-06 2.501e-05
30 ENDOCYTIC VESICLE 10 256 2.46e-06 4.788e-05
31 AXON 12 418 5.755e-06 0.0001084
32 CHROMOSOME 17 880 1.267e-05 0.0002311
33 RECEPTOR COMPLEX 10 327 2.098e-05 0.0003714
34 MEMBRANE REGION 19 1134 2.736e-05 0.00047
35 CELL PROJECTION PART 17 946 3.187e-05 0.0005318
36 CELL LEADING EDGE 10 350 3.74e-05 0.0006067
37 MICROTUBULE CYTOSKELETON 18 1068 4.233e-05 0.0006681
38 MEMBRANE MICRODOMAIN 9 288 4.666e-05 0.000717
39 NUCLEAR CHROMOSOME 12 523 5.262e-05 0.0007879
40 MICROTUBULE ORGANIZING CENTER 13 623 6.678e-05 0.000975
41 CYTOSKELETAL PART 21 1436 7.222e-05 0.001029
42 PLASMA MEMBRANE REGION 16 929 9.17e-05 0.001275
43 PROTEIN KINASE COMPLEX 5 90 0.0001786 0.002426
44 AXONAL GROWTH CONE 3 20 0.0002017 0.002677
45 NEURONAL POSTSYNAPTIC DENSITY 4 53 0.0002527 0.003208
46 CHROMATIN 10 441 0.0002497 0.003208
47 CELL CELL ADHERENS JUNCTION 4 54 0.0002717 0.003375
48 NUCLEAR CHROMATIN 8 291 0.0002982 0.003486
49 PLATELET ALPHA GRANULE LUMEN 4 55 0.0002917 0.003486
50 DENDRITE 10 451 0.0002984 0.003486
51 CATALYTIC COMPLEX 16 1038 0.0003238 0.003708
52 CYTOPLASMIC MICROTUBULE 4 57 0.0003348 0.00376
53 SYNAPSE 13 754 0.0004325 0.004766
54 LAMELLIPODIUM 6 172 0.0005039 0.005449
55 GOLGI APPARATUS 19 1445 0.0006331 0.006722
56 CELL CORTEX PART 5 119 0.0006497 0.006775
57 ACTIN FILAMENT 4 70 0.0007335 0.007515
58 CYCLIN DEPENDENT PROTEIN KINASE HOLOENZYME COMPLEX 3 31 0.0007591 0.007643
59 HISTONE METHYLTRANSFERASE COMPLEX 4 71 0.0007738 0.007659
60 MEMBRANE PROTEIN COMPLEX 15 1020 0.0008181 0.007963
61 SYNAPSE PART 11 610 0.0008444 0.008084
62 PLATELET ALPHA GRANULE 4 75 0.0009509 0.008957
63 EXCITATORY SYNAPSE 6 197 0.001024 0.009489

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04390_Hippo_signaling_pathway 116 154 9.93199999999999e-273 1.788e-270
2 hsa04310_Wnt_signaling_pathway 42 151 6.966e-61 6.269e-59
3 hsa04916_Melanogenesis 26 101 2.351e-36 1.41e-34
4 hsa04350_TGF.beta_signaling_pathway 24 85 1.125e-34 5.063e-33
5 hsa04340_Hedgehog_signaling_pathway 21 56 1.818e-33 6.544e-32
6 hsa04520_Adherens_junction 15 73 1.219e-19 3.657e-18
7 hsa04530_Tight_junction 17 133 1.995e-18 5.131e-17
8 hsa04110_Cell_cycle 16 128 3.068e-17 6.902e-16
9 hsa04114_Oocyte_meiosis 12 114 2.726e-12 5.453e-11
10 hsa04144_Endocytosis 14 203 1.282e-11 2.307e-10
11 hsa04151_PI3K_AKT_signaling_pathway 15 351 1.898e-09 3.106e-08
12 hsa04510_Focal_adhesion 9 200 2.531e-06 3.797e-05
13 hsa04115_p53_signaling_pathway 6 69 2.975e-06 4.119e-05
14 hsa04810_Regulation_of_actin_cytoskeleton 9 214 4.403e-06 5.661e-05
15 hsa04710_Circadian_rhythm_._mammal 4 23 8.736e-06 0.0001042
16 hsa04722_Neurotrophin_signaling_pathway 7 127 9.263e-06 0.0001042
17 hsa04910_Insulin_signaling_pathway 6 138 0.0001542 0.001632
18 hsa04010_MAPK_signaling_pathway 8 268 0.0001708 0.001708
19 hsa04670_Leukocyte_transendothelial_migration 5 117 0.0006015 0.005698
20 hsa03015_mRNA_surveillance_pathway 4 83 0.001388 0.01249
21 hsa04380_Osteoclast_differentiation 4 128 0.006602 0.05659
22 hsa04720_Long.term_potentiation 3 70 0.007848 0.06421
23 hsa04630_Jak.STAT_signaling_pathway 4 155 0.01271 0.0995
24 hsa04012_ErbB_signaling_pathway 3 87 0.01416 0.1062
25 hsa04270_Vascular_smooth_muscle_contraction 3 116 0.03003 0.2162
26 hsa04145_Phagosome 3 156 0.06241 0.4161
27 hsa04730_Long.term_depression 2 70 0.06241 0.4161
28 hsa04062_Chemokine_signaling_pathway 3 189 0.09742 0.6263
29 hsa04120_Ubiquitin_mediated_proteolysis 2 139 0.193 1
30 hsa04014_Ras_signaling_pathway 2 236 0.3985 1

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1

KCNQ1OT1

hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-205-5p;hsa-miR-2355-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-34c-3p;hsa-miR-34c-5p;hsa-miR-944 11 PARD6B Sponge network -0.725 0.08874 0.156 0.70726 0.605
2

PLAC4

hsa-let-7a-3p;hsa-let-7b-5p;hsa-miR-205-5p;hsa-miR-2355-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-34c-3p;hsa-miR-34c-5p;hsa-miR-9-3p;hsa-miR-944 10 PARD6B Sponge network -0.563 0.27163 0.156 0.70726 0.513
3 DGCR5 hsa-miR-140-3p;hsa-miR-140-5p;hsa-miR-146a-5p;hsa-miR-148a-5p;hsa-miR-200a-3p;hsa-miR-200b-3p;hsa-miR-29b-2-5p;hsa-miR-30d-5p;hsa-miR-362-3p;hsa-miR-375;hsa-miR-501-5p 11 FRMD6 Sponge network 1.383 0.01835 0.285 0.63104 0.501
4

AGAP11

hsa-let-7g-3p;hsa-miR-1301-3p;hsa-miR-130b-5p;hsa-miR-135b-5p;hsa-miR-148b-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-29b-1-5p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-421;hsa-miR-590-5p;hsa-miR-769-3p;hsa-miR-93-3p 20 DLG2 Sponge network -1.728 0.00016 -3.966 0 0.464
5

EMX2OS

hsa-let-7g-3p;hsa-miR-130b-5p;hsa-miR-135b-5p;hsa-miR-148b-3p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-19a-3p;hsa-miR-20a-5p;hsa-miR-27a-5p;hsa-miR-29b-1-5p;hsa-miR-3127-5p;hsa-miR-32-3p;hsa-miR-335-3p;hsa-miR-33b-5p;hsa-miR-378a-5p;hsa-miR-592;hsa-miR-7-1-3p;hsa-miR-877-5p;hsa-miR-92a-3p;hsa-miR-92b-3p;hsa-miR-93-3p 24 DLG2 Sponge network -1.088 0.10042 -3.966 0 0.46
6

AGAP11

hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-140-5p;hsa-miR-146a-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-29b-1-5p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-501-5p;hsa-miR-550a-3p 11 FRMD6 Sponge network -1.728 0.00016 0.285 0.63104 0.449
7

KCNQ1OT1

hsa-let-7a-3p;hsa-let-7b-3p;hsa-miR-100-5p;hsa-miR-149-5p;hsa-miR-181a-2-3p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-24-3p;hsa-miR-296-5p;hsa-miR-744-3p;hsa-miR-9-5p 11 FZD5 Sponge network -0.725 0.08874 -0.562 0.20161 0.449
8

PCA3

hsa-let-7g-3p;hsa-miR-1301-3p;hsa-miR-130b-5p;hsa-miR-135b-5p;hsa-miR-148b-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-23a-3p;hsa-miR-24-3p;hsa-miR-25-3p;hsa-miR-32-3p;hsa-miR-320b;hsa-miR-335-5p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-3613-5p;hsa-miR-576-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-616-5p;hsa-miR-769-3p;hsa-miR-769-5p;hsa-miR-93-3p;hsa-miR-940 32 DLG2 Sponge network -2.778 8.0E-5 -3.966 0 0.445
9

FAM95B1

hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-185-5p;hsa-miR-23a-3p;hsa-miR-24-3p;hsa-miR-3928-3p;hsa-miR-484;hsa-miR-877-5p;hsa-miR-93-3p;hsa-miR-940 10 DLG2 Sponge network -1.726 0.00466 -3.966 0 0.43
10

PCA3

hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-219a-5p;hsa-miR-224-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-301a-3p;hsa-miR-324-3p;hsa-miR-33a-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-708-5p;hsa-miR-940 28 FZD4 Sponge network -2.778 8.0E-5 -1.774 0 0.38
11 FAM66C hsa-let-7g-3p;hsa-miR-135b-5p;hsa-miR-182-5p;hsa-miR-24-3p;hsa-miR-29b-1-5p;hsa-miR-33a-5p;hsa-miR-3613-5p;hsa-miR-429;hsa-miR-590-3p;hsa-miR-590-5p 10 DLG2 Sponge network -0.353 0.40349 -3.966 0 0.369
12

RFPL1S

hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-146a-5p;hsa-miR-148a-5p;hsa-miR-200a-3p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-29b-1-5p;hsa-miR-320b;hsa-miR-362-3p;hsa-miR-375;hsa-miR-429;hsa-miR-550a-3p;hsa-miR-7-1-3p 15 FRMD6 Sponge network -0.223 0.70704 0.285 0.63104 0.361
13 MALAT1 hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-15b-5p;hsa-miR-17-3p;hsa-miR-185-5p;hsa-miR-224-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-324-3p;hsa-miR-452-5p;hsa-miR-455-3p;hsa-miR-92b-3p 13 FZD4 Sponge network -1.099 0.0005 -1.774 0 0.338
14

EMX2OS

hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-17-5p;hsa-miR-200a-3p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-29b-1-5p;hsa-miR-335-3p;hsa-miR-362-3p;hsa-miR-550a-3p;hsa-miR-7-1-3p 12 FRMD6 Sponge network -1.088 0.10042 0.285 0.63104 0.333
15

KCNQ1OT1

hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-miR-224-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-324-3p;hsa-miR-452-5p;hsa-miR-708-5p 10 FZD4 Sponge network -0.725 0.08874 -1.774 0 0.329
16

AGAP11

hsa-miR-16-1-3p;hsa-miR-18a-5p;hsa-miR-222-5p;hsa-miR-26b-3p;hsa-miR-29a-5p;hsa-miR-320b;hsa-miR-326;hsa-miR-532-3p;hsa-miR-590-5p;hsa-miR-629-5p 10 FGF1 Sponge network -1.728 0.00016 -0.16 0.73397 0.329
17

PART1

hsa-miR-135b-5p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-29b-1-5p;hsa-miR-3127-5p;hsa-miR-335-3p;hsa-miR-592;hsa-miR-7-1-3p;hsa-miR-877-5p 11 DLG2 Sponge network -2.298 0.00168 -3.966 0 0.326
18

PCA3

hsa-let-7a-3p;hsa-let-7b-3p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-181a-2-3p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-19b-3p;hsa-miR-224-3p;hsa-miR-301a-3p;hsa-miR-3065-3p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-93-5p;hsa-miR-96-5p 20 CCND2 Sponge network -2.778 8.0E-5 -0.496 0.3 0.318
19

MEG3

hsa-miR-103a-3p;hsa-miR-107;hsa-miR-130b-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-33a-3p;hsa-miR-429;hsa-miR-93-5p;hsa-miR-96-5p 11 LATS2 Sponge network -1.645 0.00049 -0.487 0.03153 0.31
20

MEG3

hsa-let-7d-5p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-219a-5p;hsa-miR-324-3p;hsa-miR-33a-3p;hsa-miR-629-3p 16 FZD4 Sponge network -1.645 0.00049 -1.774 0 0.304
21

MEG3

hsa-let-7g-3p;hsa-miR-130b-5p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-29b-1-5p;hsa-miR-3127-5p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-335-5p;hsa-miR-378a-5p;hsa-miR-3928-3p;hsa-miR-429;hsa-miR-592;hsa-miR-616-5p;hsa-miR-7-1-3p;hsa-miR-769-5p;hsa-miR-93-3p 23 DLG2 Sponge network -1.645 0.00049 -3.966 0 0.304
22

RFPL1S

hsa-miR-126-5p;hsa-miR-18a-5p;hsa-miR-222-5p;hsa-miR-26b-3p;hsa-miR-29a-5p;hsa-miR-320b;hsa-miR-330-5p;hsa-miR-429;hsa-miR-532-3p;hsa-miR-550a-5p;hsa-miR-625-5p;hsa-miR-7-5p 12 FGF1 Sponge network -0.223 0.70704 -0.16 0.73397 0.3
23

RFPL1S

hsa-miR-135b-5p;hsa-miR-148b-3p;hsa-miR-148b-5p;hsa-miR-29b-1-5p;hsa-miR-320b;hsa-miR-335-5p;hsa-miR-378a-5p;hsa-miR-429;hsa-miR-505-5p;hsa-miR-7-1-3p;hsa-miR-877-5p 11 DLG2 Sponge network -0.223 0.70704 -3.966 0 0.291
24

MEG3

hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-335-5p;hsa-miR-3615;hsa-miR-550a-5p;hsa-miR-92a-1-5p 14 WTIP Sponge network -1.645 0.00049 -0.967 0.00385 0.29
25

PCA3

hsa-miR-103a-3p;hsa-miR-107;hsa-miR-130b-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-188-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-25-3p;hsa-miR-27a-3p;hsa-miR-33a-3p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-93-5p;hsa-miR-96-5p 15 LATS2 Sponge network -2.778 8.0E-5 -0.487 0.03153 0.289
26

PCA3

hsa-miR-106b-5p;hsa-miR-130a-3p;hsa-miR-130b-3p;hsa-miR-17-5p;hsa-miR-18a-5p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-23a-3p;hsa-miR-301a-3p;hsa-miR-320b;hsa-miR-33a-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-93-5p 14 TGFBR2 Sponge network -2.778 8.0E-5 -1.331 0.00013 0.283
27

PLAC4

hsa-let-7a-3p;hsa-let-7b-5p;hsa-miR-224-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-324-3p;hsa-miR-455-3p;hsa-miR-708-5p;hsa-miR-940 10 FZD4 Sponge network -0.563 0.27163 -1.774 0 0.277
28 CASC2 hsa-let-7a-3p;hsa-let-7b-5p;hsa-miR-224-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-324-3p;hsa-miR-452-5p;hsa-miR-455-3p;hsa-miR-708-5p;hsa-miR-940 11 FZD4 Sponge network -0.561 0.05962 -1.774 0 0.271
29

FAM95B1

hsa-miR-185-5p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-324-3p;hsa-miR-452-5p;hsa-miR-455-3p;hsa-miR-484;hsa-miR-629-3p;hsa-miR-708-5p;hsa-miR-940 10 FZD4 Sponge network -1.726 0.00466 -1.774 0 0.268
30

RFPL1S

hsa-miR-141-3p;hsa-miR-17-3p;hsa-miR-18a-5p;hsa-miR-1976;hsa-miR-200a-3p;hsa-miR-29a-3p;hsa-miR-29a-5p;hsa-miR-29b-3p;hsa-miR-320b;hsa-miR-335-5p;hsa-miR-627-5p;hsa-miR-7-1-3p 12 WWTR1 Sponge network -0.223 0.70704 -0.71 0.03868 0.267
31

EMX2OS

hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-17-3p;hsa-miR-18a-5p;hsa-miR-200a-3p;hsa-miR-29a-5p;hsa-miR-32-3p;hsa-miR-335-3p;hsa-miR-627-5p;hsa-miR-7-1-3p;hsa-miR-93-3p 11 WWTR1 Sponge network -1.088 0.10042 -0.71 0.03868 0.266

Quest ID: 4c65ec57166df3abbc902b43ca119d92