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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-let-7a-3p ABCA1 0.1 0.42376 0.66 0.00011 mirMAP; miRNATAP -0.15 0.01439 NA
2 hsa-miR-361-5p ABCA1 0.08 0.31404 0.66 0.00011 miRanda; mirMAP -0.27 0.0046 NA
3 hsa-miR-590-3p ABCA1 0.22 0.09659 0.66 0.00011 miRanda -0.14 0.01172 NA
4 hsa-miR-361-5p ABCA10 0.08 0.31404 -0.69 0.01074 miRanda; mirMAP -0.38 0.01235 NA
5 hsa-let-7a-3p ABCA5 0.1 0.42376 -1.08 0 mirMAP -0.1 0.04663 NA
6 hsa-miR-181b-5p ABCA5 0.97 0 -1.08 0 mirMAP -0.32 0 NA
7 hsa-miR-590-3p ABCA6 0.22 0.09659 -1.22 0 MirTarget; miRanda -0.18 0.02797 NA
8 hsa-miR-590-3p ABCA8 0.22 0.09659 -3.87 0 miRanda -0.29 0.03136 NA
9 hsa-miR-590-3p ABCA9 0.22 0.09659 -1.42 0 miRanda -0.2 0.01781 NA
10 hsa-let-7a-3p ABCC4 0.1 0.42376 0.56 3.0E-5 mirMAP -0.13 0.00972 NA
11 hsa-miR-125a-5p ABCC4 0.22 0.11955 0.56 3.0E-5 miRanda -0.18 2.0E-5 NA
12 hsa-let-7a-3p ABCC9 0.1 0.42376 -0.52 0.04626 mirMAP -0.49 0 NA
13 hsa-miR-590-3p ABCC9 0.22 0.09659 -0.52 0.04626 miRanda; mirMAP -0.39 0 NA
14 hsa-let-7a-3p ABCD2 0.1 0.42376 -1.3 1.0E-5 mirMAP -0.55 0 NA
15 hsa-miR-361-5p ABCD2 0.08 0.31404 -1.3 1.0E-5 miRanda -0.82 0 NA
16 hsa-miR-15a-5p ABCG4 0.78 0 -0.69 0.02172 MirTarget; miRNATAP -0.26 0.0179 NA
17 hsa-miR-125a-5p ABHD2 0.22 0.11955 -0.22 0.10264 miRanda; mirMAP -0.18 1.0E-5 NA
18 hsa-miR-590-3p ABHD2 0.22 0.09659 -0.22 0.10264 miRanda; mirMAP -0.13 0.00314 NA
19 hsa-miR-125a-5p ABHD3 0.22 0.11955 0.5 2.0E-5 PITA; miRanda -0.1 0.00596 NA
20 hsa-miR-181b-5p ABI1 0.97 0 -0.24 0.0098 MirTarget -0.24 0 NA
21 hsa-let-7a-3p ABI3BP 0.1 0.42376 -2.63 0 miRNATAP -0.64 0 NA
22 hsa-miR-590-3p ABI3BP 0.22 0.09659 -2.63 0 miRanda -0.25 0.02651 NA
23 hsa-miR-15a-5p ABL2 0.78 0 1.1 0 MirTarget; miRNATAP -0.13 0.00304 NA
24 hsa-miR-200c-3p ABL2 0.63 0.00013 1.1 0 MirTarget -0.13 0.0001 NA
25 hsa-miR-590-3p ABL2 0.22 0.09659 1.1 0 PITA; mirMAP; miRNATAP -0.11 0.00782 NA
26 hsa-let-7a-3p ABLIM1 0.1 0.42376 -1.46 0 mirMAP -0.18 0.00349 NA
27 hsa-miR-590-3p ABLIM1 0.22 0.09659 -1.46 0 miRanda; mirMAP -0.18 0.00162 NA
28 hsa-miR-590-3p ABRA 0.22 0.09659 -3.48 0 miRanda; mirMAP -0.41 0.00735 NA
29 hsa-miR-15a-5p ABTB2 0.78 0 -0.21 0.26213 MirTarget -0.34 0 NA
30 hsa-miR-181b-5p ACAD8 0.97 0 -1.04 0 MirTarget -0.15 3.0E-5 NA
31 hsa-miR-590-3p ACADL 0.22 0.09659 -3.75 0 miRanda -0.44 0.00064 NA
32 hsa-let-7a-3p ACAP2 0.1 0.42376 0.11 0.40427 MirTarget; mirMAP; miRNATAP -0.24 0 NA
33 hsa-miR-181b-5p ACAP2 0.97 0 0.11 0.40427 MirTarget; miRNATAP -0.28 0 NA
34 hsa-miR-590-3p ACBD3 0.22 0.09659 -0.2 0.01125 miRanda -0.11 4.0E-5 NA
35 hsa-miR-361-5p ACBD5 0.08 0.31404 -0.32 0.00033 miRanda -0.13 0.00874 NA
36 hsa-miR-125a-5p ACER2 0.22 0.11955 -0.24 0.26552 MirTarget; miRanda -0.47 0 NA
37 hsa-miR-361-5p ACLY 0.08 0.31404 0.64 0 miRNAWalker2 validate; miRanda -0.11 0.03564 NA
38 hsa-miR-15a-5p ACOT11 0.78 0 -0.47 0.01215 mirMAP -0.16 0.02163 NA
39 hsa-miR-590-3p ACOT11 0.22 0.09659 -0.47 0.01215 mirMAP -0.13 0.03269 NA
40 hsa-miR-15a-5p ACOX1 0.78 0 -0.92 0 miRNATAP -0.28 0 NA
41 hsa-miR-590-3p ACOX1 0.22 0.09659 -0.92 0 miRanda; mirMAP -0.11 0.00019 NA
42 hsa-miR-590-3p ACOX2 0.22 0.09659 -2.33 0 miRanda -0.15 0.04424 NA
43 hsa-miR-125a-5p ACPP 0.22 0.11955 -2.13 0 MirTarget; miRanda -0.42 0 NA
44 hsa-miR-590-3p ACPP 0.22 0.09659 -2.13 0 miRanda; miRNATAP -0.23 0.00936 NA
45 hsa-miR-15a-5p ACSBG1 0.78 0 -1.43 0 MirTarget -0.27 0.00141 NA
46 hsa-miR-181b-5p ACSL1 0.97 0 -1.24 0 MirTarget -0.41 0 NA
47 hsa-miR-590-3p ACSL1 0.22 0.09659 -1.24 0 miRanda -0.18 0.00018 NA
48 hsa-miR-15a-5p ACSL4 0.78 0 0.09 0.51888 MirTarget; miRNATAP -0.23 0 NA
49 hsa-miR-181b-5p ACSL6 0.97 0 -1.41 0 miRNATAP -0.23 0.02086 NA
50 hsa-miR-181b-5p ACSS1 0.97 0 -0.09 0.62166 mirMAP -0.12 0.04826 NA
51 hsa-miR-15a-5p ACSS2 0.78 0 -0.83 0 MirTarget -0.11 0.00425 NA
52 hsa-miR-181b-5p ACSS3 0.97 0 -2.16 0 MirTarget -0.21 0.04571 NA
53 hsa-miR-590-3p ACSS3 0.22 0.09659 -2.16 0 miRanda -0.42 1.0E-5 NA
54 hsa-miR-200c-3p ACTC1 0.63 0.00013 -2.11 0.00795 MirTarget -1.36 0 NA
55 hsa-miR-590-3p ACTC1 0.22 0.09659 -2.11 0.00795 miRanda -0.88 0.00074 NA
56 hsa-miR-361-5p ACTG1 0.08 0.31404 -0.14 0.09417 miRNAWalker2 validate; MirTarget; PITA; miRanda; miRNATAP -0.11 0.01405 NA
57 hsa-miR-590-3p ACTG2 0.22 0.09659 -1.13 6.0E-5 miRanda -0.42 1.0E-5 NA
58 hsa-miR-15a-5p ACTR2 0.78 0 0.17 0.03937 MirTarget; miRNATAP -0.14 0 NA
59 hsa-miR-590-3p ACVR1 0.22 0.09659 0.7 0 miRanda -0.17 1.0E-5 NA
60 hsa-miR-15a-5p ACVR1B 0.78 0 -0.22 0.01253 miRNAWalker2 validate -0.16 0 NA
61 hsa-miR-15a-5p ACVR2A 0.78 0 -0.89 0 MirTarget; miRNATAP -0.2 0 NA
62 hsa-miR-181b-5p ACVR2A 0.97 0 -0.89 0 MirTarget; miRNATAP -0.3 0 NA
63 hsa-miR-590-3p ACVR2A 0.22 0.09659 -0.89 0 MirTarget; PITA; miRanda; miRNATAP -0.11 0.00364 NA
64 hsa-let-7a-3p ACVR2B 0.1 0.42376 0.2 0.10824 MirTarget -0.16 0.0003 NA
65 hsa-miR-590-3p ACYP2 0.22 0.09659 -1.15 0 miRanda; mirMAP; miRNATAP -0.1 0.01636 NA
66 hsa-miR-125a-5p ADAM10 0.22 0.11955 0.48 0.00248 miRanda -0.33 0 NA
67 hsa-miR-361-5p ADAM10 0.08 0.31404 0.48 0.00248 miRanda -0.18 0.03828 NA
68 hsa-miR-590-3p ADAM10 0.22 0.09659 0.48 0.00248 MirTarget; PITA; miRanda -0.13 0.01537 NA
69 hsa-miR-181b-5p ADAM11 0.97 0 -0.59 0.00626 MirTarget; miRNATAP -0.15 0.04789 NA
70 hsa-miR-590-3p ADAM12 0.22 0.09659 3.78 0 mirMAP -0.3 0.00348 NA
71 hsa-miR-590-3p ADAM17 0.22 0.09659 0.52 0.0008 mirMAP -0.13 0.01335 NA
72 hsa-miR-361-5p ADAM19 0.08 0.31404 1.35 0 miRanda -0.4 0.00117 NA
73 hsa-miR-181b-5p ADAM22 0.97 0 -0.46 0.16333 mirMAP; miRNATAP -0.36 0.00178 NA
74 hsa-let-7a-3p ADAM23 0.1 0.42376 0.9 0.01408 mirMAP -0.7 0 NA
75 hsa-miR-590-3p ADAM23 0.22 0.09659 0.9 0.01408 miRanda -0.29 0.01506 NA
76 hsa-miR-361-5p ADAM28 0.08 0.31404 -0.51 0.07502 mirMAP -0.55 0.00063 NA
77 hsa-miR-590-3p ADAM33 0.22 0.09659 -1.06 3.0E-5 miRanda -0.21 0.01013 NA
78 hsa-miR-125a-5p ADAM9 0.22 0.11955 0.33 0.01532 PITA; miRanda -0.16 0.00019 NA
79 hsa-miR-590-3p ADAMTS1 0.22 0.09659 -0.83 9.0E-5 miRanda -0.21 0.00225 NA
80 hsa-miR-590-3p ADAMTS14 0.22 0.09659 2.02 0 miRanda -0.16 0.03149 NA
81 hsa-miR-125a-5p ADAMTS15 0.22 0.11955 0.72 0.06817 mirMAP -0.34 0.00596 NA
82 hsa-miR-590-3p ADAMTS16 0.22 0.09659 1.13 0.00568 miRanda; mirMAP -0.58 1.0E-5 NA
83 hsa-miR-15a-5p ADAMTS18 0.78 0 -0.15 0.62986 miRNATAP -0.44 9.0E-5 NA
84 hsa-miR-15a-5p ADAMTS3 0.78 0 0.25 0.32288 miRNATAP -0.39 1.0E-5 NA
85 hsa-miR-200c-3p ADAMTS3 0.63 0.00013 0.25 0.32288 miRNATAP -0.27 3.0E-5 NA
86 hsa-miR-590-3p ADAMTS3 0.22 0.09659 0.25 0.32288 miRanda; mirMAP -0.24 0.00326 NA
87 hsa-let-7a-3p ADAMTS5 0.1 0.42376 0.22 0.3564 mirMAP -0.43 0 NA
88 hsa-miR-15a-5p ADAMTS5 0.78 0 0.22 0.3564 miRNATAP -0.61 0 NA
89 hsa-miR-590-3p ADAMTS5 0.22 0.09659 0.22 0.3564 PITA; miRanda; miRNATAP -0.39 0 NA
90 hsa-miR-590-3p ADAMTS8 0.22 0.09659 -2.58 0 miRanda -0.28 0.00484 NA
91 hsa-miR-590-3p ADAMTS9 0.22 0.09659 -0.42 0.04672 miRanda -0.29 3.0E-5 NA
92 hsa-miR-590-3p ADAMTSL1 0.22 0.09659 -0.59 0.02163 miRanda; mirMAP -0.32 0.00019 NA
93 hsa-let-7a-3p ADAMTSL3 0.1 0.42376 -2.24 0 MirTarget -0.56 1.0E-5 NA
94 hsa-miR-15a-5p ADAMTSL3 0.78 0 -2.24 0 MirTarget -0.9 0 NA
95 hsa-miR-590-3p ADAMTSL5 0.22 0.09659 -0.11 0.57927 miRanda -0.15 0.02055 NA
96 hsa-miR-181b-5p ADARB2 0.97 0 -2.34 0 MirTarget -0.58 3.0E-5 NA
97 hsa-miR-15a-5p ADCY1 0.78 0 0.05 0.82032 mirMAP -0.31 0.00028 NA
98 hsa-miR-200c-3p ADCY2 0.63 0.00013 -2.75 0 MirTarget; miRNATAP -0.62 0 NA
99 hsa-miR-590-3p ADCY2 0.22 0.09659 -2.75 0 mirMAP -0.51 0.00037 NA
100 hsa-miR-15a-5p ADCY5 0.78 0 -2.26 0 MirTarget; miRNATAP -0.77 0 NA
101 hsa-miR-125a-5p ADCY9 0.22 0.11955 -0.39 0.00115 mirMAP -0.11 0.00284 NA
102 hsa-miR-181b-5p ADCY9 0.97 0 -0.39 0.00115 miRNATAP -0.11 0.01129 24269684 miR 181b promotes cell proliferation and reduces apoptosis by repressing the expression of adenylyl cyclase 9 AC9 in cervical cancer cells; Phenotypic experiments indicated that miR-181b and AC9 exerted opposite effects on cell proliferation and apoptosis
103 hsa-miR-590-3p ADCY9 0.22 0.09659 -0.39 0.00115 miRanda -0.14 0.00035 NA
104 hsa-let-7a-3p ADD2 0.1 0.42376 1.03 0.01025 mirMAP -0.47 0.0012 NA
105 hsa-let-7a-3p ADD3 0.1 0.42376 -0.34 0.02607 mirMAP; miRNATAP -0.25 1.0E-5 NA
106 hsa-miR-590-3p ADIPOQ 0.22 0.09659 -7.62 0 PITA; miRanda; mirMAP -0.35 0.0444 NA
107 hsa-miR-590-3p AFAP1 0.22 0.09659 0.45 0.0007 PITA; miRanda; miRNATAP -0.13 0.00318 NA
108 hsa-miR-181b-5p AFF1 0.97 0 -0.59 0 mirMAP; miRNATAP -0.22 0 NA
109 hsa-let-7a-3p AFF2 0.1 0.42376 0.95 0.01105 mirMAP -0.5 0.00021 NA
110 hsa-miR-590-3p AFF2 0.22 0.09659 0.95 0.01105 PITA; miRanda; mirMAP; miRNATAP -0.29 0.018 NA
111 hsa-let-7a-3p AFF3 0.1 0.42376 -1.67 0 MirTarget -0.75 0 NA
112 hsa-miR-200c-3p AFF3 0.63 0.00013 -1.67 0 MirTarget; miRNATAP -0.26 0.00088 NA
113 hsa-let-7a-3p AFF4 0.1 0.42376 -0.51 1.0E-5 MirTarget; mirMAP -0.2 0 NA
114 hsa-miR-15a-5p AFF4 0.78 0 -0.51 1.0E-5 MirTarget; miRNATAP -0.35 0 NA
115 hsa-miR-181b-5p AFF4 0.97 0 -0.51 1.0E-5 mirMAP; miRNATAP -0.13 0.00113 NA
116 hsa-miR-361-5p AFF4 0.08 0.31404 -0.51 1.0E-5 miRanda -0.22 0.00056 NA
117 hsa-miR-590-3p AFF4 0.22 0.09659 -0.51 1.0E-5 MirTarget; PITA; miRanda; mirMAP; miRNATAP -0.1 0.00735 NA
118 hsa-miR-181b-5p AFG3L2 0.97 0 -0.24 0.00364 MirTarget; miRNATAP -0.17 0 NA
119 hsa-miR-181b-5p AFTPH 0.97 0 -0.31 2.0E-5 MirTarget; miRNATAP -0.2 0 NA
120 hsa-miR-590-3p AGAP1 0.22 0.09659 -0.34 0.00122 miRanda; mirMAP -0.13 0.00017 NA
121 hsa-miR-181b-5p AGFG2 0.97 0 -1.89 0 mirMAP -0.39 0 NA
122 hsa-miR-125a-5p AGGF1 0.22 0.11955 -0.19 0.00569 miRanda -0.1 0 NA
123 hsa-miR-181b-5p AGGF1 0.97 0 -0.19 0.00569 mirMAP -0.13 0 NA
124 hsa-miR-181b-5p AGPAT3 0.97 0 -0.73 0 MirTarget -0.13 0.00036 NA
125 hsa-miR-590-3p AGT 0.22 0.09659 -2 0 miRanda -0.36 0.00132 NA
126 hsa-miR-590-3p AGTR1 0.22 0.09659 -1.69 0 miRanda -0.74 0 NA
127 hsa-miR-15a-5p AHCYL2 0.78 0 -0.77 0 miRNATAP -0.34 0 NA
128 hsa-let-7a-3p AHDC1 0.1 0.42376 -0.61 0 miRNATAP -0.15 0.00016 NA
129 hsa-miR-590-3p AHNAK 0.22 0.09659 -0.84 0 miRanda -0.31 0 NA
130 hsa-miR-590-3p AHR 0.22 0.09659 0.5 0.00053 MirTarget; miRanda; mirMAP -0.12 0.00925 NA
131 hsa-miR-361-5p AIG1 0.08 0.31404 -0.31 0.00356 miRanda -0.13 0.02803 NA
132 hsa-miR-590-3p AIG1 0.22 0.09659 -0.31 0.00356 miRanda -0.12 0.00051 NA
133 hsa-miR-361-5p AK3 0.08 0.31404 -0.85 0 miRanda -0.26 5.0E-5 NA
134 hsa-miR-590-3p AK5 0.22 0.09659 0.65 0.03015 miRanda; mirMAP -0.44 1.0E-5 NA
135 hsa-let-7a-3p AKAP11 0.1 0.42376 -0.24 0.02908 mirMAP -0.18 0 NA
136 hsa-miR-125a-5p AKAP11 0.22 0.11955 -0.24 0.02908 miRanda -0.18 0 NA
137 hsa-miR-15a-5p AKAP11 0.78 0 -0.24 0.02908 MirTarget; miRNATAP -0.22 0 NA
138 hsa-let-7a-3p AKAP12 0.1 0.42376 -1.13 0 miRNATAP -0.52 0 NA
139 hsa-miR-590-3p AKAP12 0.22 0.09659 -1.13 0 miRanda; mirMAP -0.33 4.0E-5 NA
140 hsa-miR-125a-5p AKAP13 0.22 0.11955 -0.31 0.00164 miRanda -0.2 0 NA
141 hsa-miR-590-3p AKAP13 0.22 0.09659 -0.31 0.00164 PITA; miRanda; mirMAP -0.16 0 NA
142 hsa-miR-590-3p AKAP3 0.22 0.09659 -1.1 0 PITA; miRanda; miRNATAP -0.15 0.02316 NA
143 hsa-miR-361-5p AKAP5 0.08 0.31404 1.17 0 miRanda -0.32 0.00241 NA
144 hsa-miR-590-3p AKAP6 0.22 0.09659 -2.06 0 MirTarget; PITA; miRanda; mirMAP -0.42 1.0E-5 NA
145 hsa-let-7a-3p AKAP9 0.1 0.42376 -0.65 0 MirTarget -0.19 2.0E-5 NA
146 hsa-miR-590-3p AKAP9 0.22 0.09659 -0.65 0 miRanda -0.1 0.01408 NA
147 hsa-miR-361-5p AKR1B10 0.08 0.31404 0.12 0.77773 miRanda -0.77 0.00154 NA
148 hsa-miR-181b-5p AKR1C1 0.97 0 0.01 0.97742 mirMAP -0.66 0 NA
149 hsa-miR-590-3p AKR1C2 0.22 0.09659 0.08 0.85373 mirMAP -0.33 0.01562 NA
150 hsa-miR-15a-5p AKT3 0.78 0 0.76 5.0E-5 miRNAWalker2 validate; miRTarBase; miRNATAP -0.27 0.00011 NA
NumGOOverlapSizeP ValueAdj. P Value
1 TISSUE DEVELOPMENT 467 1518 2.914e-49 1.356e-45
2 CARDIOVASCULAR SYSTEM DEVELOPMENT 288 788 1.574e-45 2.441e-42
3 CIRCULATORY SYSTEM DEVELOPMENT 288 788 1.574e-45 2.441e-42
4 NEUROGENESIS 422 1402 1.135e-41 1.32e-38
5 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 474 1672 2.297e-39 2.138e-36
6 REGULATION OF CELL DIFFERENTIATION 432 1492 4.08e-38 3.164e-35
7 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 463 1656 9.487e-37 5.518e-34
8 CELL DEVELOPMENT 414 1426 9.196e-37 5.518e-34
9 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 320 1021 4.621e-35 2.389e-32
10 BIOLOGICAL ADHESION 318 1032 2.738e-33 1.274e-30
11 RESPONSE TO ENDOGENOUS STIMULUS 408 1450 7.002e-33 2.962e-30
12 ORGAN MORPHOGENESIS 273 841 9.834e-33 3.813e-30
13 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 477 1784 1.193e-32 4.27e-30
14 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 310 1008 2.824e-32 9.385e-30
15 REGULATION OF CELLULAR COMPONENT MOVEMENT 255 771 4.865e-32 1.509e-29
16 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 235 689 8.226e-32 2.392e-29
17 EPITHELIUM DEVELOPMENT 294 945 1.418e-31 3.664e-29
18 POSITIVE REGULATION OF MOLECULAR FUNCTION 475 1791 1.366e-31 3.664e-29
19 HEART DEVELOPMENT 177 466 1.679e-30 4.111e-28
20 POSITIVE REGULATION OF GENE EXPRESSION 459 1733 2.469e-30 5.745e-28
21 REGULATION OF CELL DEVELOPMENT 265 836 6.507e-30 1.442e-27
22 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 358 1275 1.399e-28 2.854e-26
23 VASCULATURE DEVELOPMENT 174 469 1.411e-28 2.854e-26
24 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 475 1848 3.589e-28 6.958e-26
25 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 184 513 4.587e-28 8.538e-26
26 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 381 1395 7.879e-28 1.41e-25
27 TISSUE MORPHOGENESIS 187 533 3.754e-27 6.47e-25
28 POSITIVE REGULATION OF CATALYTIC ACTIVITY 404 1518 4.785e-27 7.952e-25
29 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 323 1142 2.275e-26 3.65e-24
30 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 236 750 3.444e-26 5.342e-24
31 REGULATION OF PROTEIN MODIFICATION PROCESS 438 1710 1.462e-25 2.194e-23
32 LOCOMOTION 314 1114 2.298e-25 3.342e-23
33 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 280 957 2.408e-25 3.395e-23
34 INTRACELLULAR SIGNAL TRANSDUCTION 409 1572 2.945e-25 4.031e-23
35 CELLULAR COMPONENT MORPHOGENESIS 267 900 3.563e-25 4.736e-23
36 REGULATION OF PHOSPHORUS METABOLIC PROCESS 414 1618 4.931e-24 6.373e-22
37 MUSCLE STRUCTURE DEVELOPMENT 155 432 8.075e-24 1.015e-21
38 REGULATION OF CELL MORPHOGENESIS 184 552 9.332e-24 1.143e-21
39 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 360 1360 1.286e-23 1.534e-21
40 PROTEIN PHOSPHORYLATION 272 944 1.518e-23 1.766e-21
41 BLOOD VESSEL MORPHOGENESIS 137 364 2.061e-23 2.339e-21
42 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 449 1805 2.164e-23 2.397e-21
43 NEURON DIFFERENTIATION 256 874 2.729e-23 2.953e-21
44 NEGATIVE REGULATION OF CELL COMMUNICATION 324 1192 2.808e-23 2.969e-21
45 REGULATION OF TRANSPORT 448 1804 3.515e-23 3.634e-21
46 REGULATION OF CELL PROJECTION ORGANIZATION 184 558 3.772e-23 3.816e-21
47 REGULATION OF CELL PROLIFERATION 386 1496 4.233e-23 4.191e-21
48 POSITIVE REGULATION OF CELL COMMUNICATION 393 1532 5.1e-23 4.944e-21
49 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 283 1004 6.795e-23 6.453e-21
50 REGULATION OF GTPASE ACTIVITY 210 673 6.986e-23 6.502e-21
51 REGULATION OF NEURON DIFFERENTIATION 182 554 1.054e-22 9.617e-21
52 POSITIVE REGULATION OF RESPONSE TO STIMULUS 470 1929 1.653e-22 1.479e-20
53 POSITIVE REGULATION OF HYDROLASE ACTIVITY 260 905 2.463e-22 2.162e-20
54 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 112 278 4.169e-22 3.592e-20
55 REGULATION OF HYDROLASE ACTIVITY 347 1327 8.427e-22 7.13e-20
56 RESPONSE TO GROWTH FACTOR 160 475 2.592e-21 2.154e-19
57 POSITIVE REGULATION OF CELL DIFFERENTIATION 239 823 2.982e-21 2.434e-19
58 MORPHOGENESIS OF AN EPITHELIUM 141 400 5.917e-21 4.747e-19
59 TUBE DEVELOPMENT 177 552 7.834e-21 6.178e-19
60 EMBRYO DEVELOPMENT 253 894 8.769e-21 6.801e-19
61 CELL MOTILITY 240 835 1.064e-20 7.989e-19
62 LOCALIZATION OF CELL 240 835 1.064e-20 7.989e-19
63 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 164 498 1.102e-20 8.14e-19
64 RESPONSE TO OXYGEN CONTAINING COMPOUND 354 1381 1.125e-20 8.176e-19
65 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 124 337 2.404e-20 1.721e-18
66 NEURON PROJECTION DEVELOPMENT 174 545 2.812e-20 1.983e-18
67 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 470 1977 3.151e-20 2.188e-18
68 UROGENITAL SYSTEM DEVELOPMENT 114 299 3.29e-20 2.251e-18
69 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 305 1152 4.65e-20 3.136e-18
70 REGULATION OF NEURON PROJECTION DEVELOPMENT 140 408 1.315e-19 8.738e-18
71 CENTRAL NERVOUS SYSTEM DEVELOPMENT 244 872 2.198e-19 1.441e-17
72 HEAD DEVELOPMENT 208 709 3.667e-19 2.37e-17
73 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 227 799 5.928e-19 3.778e-17
74 REGULATION OF CELL DEATH 364 1472 1.72e-18 1.081e-16
75 POSITIVE REGULATION OF LOCOMOTION 140 420 2.393e-18 1.484e-16
76 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 275 1036 2.627e-18 1.587e-16
77 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 275 1036 2.627e-18 1.587e-16
78 SKELETAL SYSTEM DEVELOPMENT 148 455 3.11e-18 1.855e-16
79 REGULATION OF EPITHELIAL CELL PROLIFERATION 106 285 5.67e-18 3.339e-16
80 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 294 1135 6.473e-18 3.765e-16
81 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 240 876 7.516e-18 4.318e-16
82 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 91 229 9.343e-18 5.301e-16
83 NEURON DEVELOPMENT 199 687 1.019e-17 5.711e-16
84 RESPONSE TO HORMONE 243 893 1.138e-17 6.232e-16
85 PHOSPHORYLATION 312 1228 1.136e-17 6.232e-16
86 GROWTH 136 410 1.174e-17 6.35e-16
87 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 210 740 1.516e-17 8.107e-16
88 REGULATION OF KINASE ACTIVITY 217 776 2.638e-17 1.395e-15
89 POSITIVE REGULATION OF CELL DEVELOPMENT 149 472 4.795e-17 2.507e-15
90 DEVELOPMENTAL GROWTH 116 333 5.043e-17 2.607e-15
91 EMBRYONIC MORPHOGENESIS 164 539 6.039e-17 3.088e-15
92 CELL PROJECTION ORGANIZATION 242 902 8.436e-17 4.267e-15
93 REGULATION OF MAPK CASCADE 189 660 2.499e-16 1.25e-14
94 ACTIN FILAMENT BASED PROCESS 142 450 2.744e-16 1.358e-14
95 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 219 801 2.904e-16 1.422e-14
96 FOREBRAIN DEVELOPMENT 120 357 3.211e-16 1.556e-14
97 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 358 1492 4.686e-16 2.248e-14
98 TUBE MORPHOGENESIS 111 323 7.19e-16 3.414e-14
99 MESENCHYME DEVELOPMENT 77 190 8.459e-16 3.936e-14
100 STEM CELL DIFFERENTIATION 77 190 8.459e-16 3.936e-14
101 REGULATION OF ACTIN FILAMENT BASED PROCESS 108 312 1.002e-15 4.604e-14
102 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 255 983 1.009e-15 4.604e-14
103 RESPONSE TO NITROGEN COMPOUND 229 859 1.297e-15 5.86e-14
104 RESPONSE TO LIPID 235 888 1.322e-15 5.915e-14
105 ANGIOGENESIS 103 293 1.433e-15 6.349e-14
106 MUSCLE ORGAN DEVELOPMENT 99 277 1.49e-15 6.542e-14
107 REGULATION OF SYSTEM PROCESS 153 507 1.509e-15 6.563e-14
108 NEURON PROJECTION MORPHOGENESIS 129 402 1.53e-15 6.593e-14
109 REGULATION OF CELLULAR COMPONENT BIOGENESIS 209 767 2.111e-15 9.013e-14
110 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 160 541 2.442e-15 1.024e-13
111 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 160 541 2.442e-15 1.024e-13
112 RESPONSE TO ORGANIC CYCLIC COMPOUND 240 917 2.541e-15 1.056e-13
113 SENSORY ORGAN DEVELOPMENT 149 493 3.1e-15 1.276e-13
114 CELLULAR RESPONSE TO HORMONE STIMULUS 162 552 3.463e-15 1.413e-13
115 NEGATIVE REGULATION OF GENE EXPRESSION 354 1493 4.403e-15 1.782e-13
116 CELLULAR RESPONSE TO NITROGEN COMPOUND 151 505 5.497e-15 2.205e-13
117 REGULATION OF EPITHELIAL CELL MIGRATION 69 166 5.782e-15 2.299e-13
118 MESENCHYMAL CELL DIFFERENTIATION 60 134 5.856e-15 2.309e-13
119 PALATE DEVELOPMENT 45 85 6.85e-15 2.679e-13
120 MUSCLE TISSUE DEVELOPMENT 97 275 7.516e-15 2.914e-13
121 HEART MORPHOGENESIS 81 212 8.061e-15 3.1e-13
122 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 119 368 1.042e-14 3.976e-13
123 POSITIVE REGULATION OF KINASE ACTIVITY 145 482 1.118e-14 4.23e-13
124 MUSCLE CELL DIFFERENTIATION 87 237 1.298e-14 4.869e-13
125 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 127 404 1.443e-14 5.371e-13
126 POSITIVE REGULATION OF CELL PROLIFERATION 216 814 1.474e-14 5.445e-13
127 NEGATIVE REGULATION OF CELL DIFFERENTIATION 172 609 2.28e-14 8.355e-13
128 NEGATIVE REGULATION OF CELL DEATH 227 872 2.817e-14 1.024e-12
129 POSITIVE REGULATION OF MAPK CASCADE 141 470 3.332e-14 1.202e-12
130 CONNECTIVE TISSUE DEVELOPMENT 75 194 3.858e-14 1.381e-12
131 BEHAVIOR 151 516 3.971e-14 1.411e-12
132 RESPONSE TO WOUNDING 161 563 4.98e-14 1.755e-12
133 EMBRYONIC ORGAN DEVELOPMENT 126 406 5.256e-14 1.839e-12
134 REGULATION OF CELL ADHESION 175 629 5.931e-14 2.059e-12
135 GLAND DEVELOPMENT 123 395 8.049e-14 2.774e-12
136 NEGATIVE REGULATION OF PHOSPHORYLATION 129 422 9.134e-14 3.125e-12
137 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 158 554 1.103e-13 3.745e-12
138 SINGLE ORGANISM BEHAVIOR 120 384 1.229e-13 4.145e-12
139 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 132 437 1.264e-13 4.231e-12
140 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 139 470 1.714e-13 5.698e-12
141 CELL CELL ADHESION 169 608 1.769e-13 5.838e-12
142 REGULATION OF TRANSFERASE ACTIVITY 239 946 1.907e-13 6.235e-12
143 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 77 207 1.916e-13 6.235e-12
144 REGULATION OF DEVELOPMENTAL GROWTH 97 289 2.486e-13 8.034e-12
145 REGULATION OF CELLULAR LOCALIZATION 304 1277 2.822e-13 9.055e-12
146 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 72 190 3.989e-13 1.271e-11
147 POSITIVE REGULATION OF TRANSPORT 235 936 6.198e-13 1.962e-11
148 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 348 1517 9.166e-13 2.882e-11
149 NEGATIVE REGULATION OF CELL PROLIFERATION 174 643 9.825e-13 3.068e-11
150 EPITHELIAL CELL DIFFERENTIATION 142 495 1.226e-12 3.804e-11
151 TAXIS 135 464 1.445e-12 4.451e-11
152 ENDOMEMBRANE SYSTEM ORGANIZATION 135 465 1.716e-12 5.253e-11
153 REGULATION OF GROWTH 171 633 1.814e-12 5.516e-11
154 REGULATION OF AXONOGENESIS 65 168 1.826e-12 5.516e-11
155 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 69 184 2.179e-12 6.541e-11
156 TELENCEPHALON DEVELOPMENT 80 228 2.322e-12 6.883e-11
157 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 98 303 2.312e-12 6.883e-11
158 MUSCLE SYSTEM PROCESS 93 282 2.423e-12 7.135e-11
159 STRIATED MUSCLE CELL DIFFERENTIATION 66 173 2.627e-12 7.689e-11
160 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 61 154 2.655e-12 7.722e-11
161 EXTRACELLULAR STRUCTURE ORGANIZATION 98 304 2.876e-12 8.312e-11
162 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 88 262 3.034e-12 8.715e-11
163 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 63 162 3.059e-12 8.733e-11
164 SKELETAL SYSTEM MORPHOGENESIS 73 201 3.137e-12 8.901e-11
165 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 47 104 3.305e-12 9.32e-11
166 REGULATION OF OSSIFICATION 67 178 3.706e-12 1.039e-10
167 POSITIVE REGULATION OF NEURON DIFFERENTIATION 98 306 4.43e-12 1.234e-10
168 REGULATION OF MAP KINASE ACTIVITY 101 319 4.505e-12 1.248e-10
169 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 127 437 7.276e-12 2.003e-10
170 EMBRYONIC ORGAN MORPHOGENESIS 91 279 8.312e-12 2.275e-10
171 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 46 103 9.353e-12 2.545e-10
172 CARDIAC CHAMBER DEVELOPMENT 57 144 1.413e-11 3.824e-10
173 MORPHOGENESIS OF A BRANCHING STRUCTURE 63 167 1.445e-11 3.886e-10
174 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 164 616 1.839e-11 4.889e-10
175 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 164 616 1.839e-11 4.889e-10
176 CELLULAR RESPONSE TO LIPID 130 457 2.083e-11 5.507e-10
177 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 55 138 2.337e-11 6.143e-10
178 REGULATION OF ANATOMICAL STRUCTURE SIZE 133 472 2.507e-11 6.555e-10
179 RHYTHMIC PROCESS 94 298 3.112e-11 8.089e-10
180 RESPONSE TO STEROID HORMONE 138 497 3.299e-11 8.528e-10
181 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 131 465 3.598e-11 9.249e-10
182 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 50 121 3.957e-11 1.012e-09
183 REGULATION OF CELL SUBSTRATE ADHESION 63 173 8.274e-11 2.104e-09
184 NEGATIVE REGULATION OF CELL DEVELOPMENT 94 303 8.611e-11 2.178e-09
185 CELL DEATH 239 1001 8.861e-11 2.229e-09
186 EYE DEVELOPMENT 99 326 1.046e-10 2.616e-09
187 NEGATIVE REGULATION OF TRANSPORT 128 458 1.075e-10 2.674e-09
188 CARTILAGE DEVELOPMENT 56 147 1.241e-10 3.071e-09
189 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 77 232 1.3e-10 3.2e-09
190 REGULATION OF PROTEIN LOCALIZATION 228 950 1.481e-10 3.628e-09
191 CARDIAC MUSCLE TISSUE DEVELOPMENT 54 140 1.533e-10 3.735e-09
192 REGULATION OF CELLULAR COMPONENT SIZE 101 337 1.553e-10 3.764e-09
193 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 55 144 1.613e-10 3.889e-09
194 COGNITION 81 251 2.066e-10 4.929e-09
195 POSITIVE REGULATION OF CELL DEATH 158 605 2.059e-10 4.929e-09
196 SYNAPSE ORGANIZATION 55 145 2.192e-10 5.205e-09
197 PALLIUM DEVELOPMENT 57 153 2.345e-10 5.538e-09
198 REGULATION OF BLOOD CIRCULATION 91 295 2.389e-10 5.614e-09
199 SENSORY ORGAN MORPHOGENESIS 78 239 2.446e-10 5.719e-09
200 REGULATION OF CELL MATRIX ADHESION 40 90 2.492e-10 5.798e-09
201 REGULATION OF ION TRANSPORT 155 592 2.51e-10 5.811e-09
202 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 222 926 2.905e-10 6.691e-09
203 REGULATION OF TRANSPORTER ACTIVITY 68 198 2.94e-10 6.74e-09
204 ACTIVATION OF PROTEIN KINASE ACTIVITY 87 279 3.217e-10 7.338e-09
205 REGULATION OF HEART CONTRACTION 73 221 4.963e-10 1.127e-08
206 REGULATION OF CELLULAR RESPONSE TO STRESS 174 691 5.45e-10 1.231e-08
207 KIDNEY EPITHELIUM DEVELOPMENT 49 125 5.563e-10 1.25e-08
208 NEURON PROJECTION GUIDANCE 69 205 5.908e-10 1.322e-08
209 PROTEIN LOCALIZATION 387 1805 6.221e-10 1.385e-08
210 WOUND HEALING 128 470 6.624e-10 1.468e-08
211 CELL JUNCTION ORGANIZATION 64 185 6.913e-10 1.525e-08
212 VASCULOGENESIS 30 59 7.836e-10 1.72e-08
213 WNT SIGNALING PATHWAY 102 351 8.442e-10 1.844e-08
214 NEGATIVE REGULATION OF LOCOMOTION 82 263 1.037e-09 2.254e-08
215 CIRCULATORY SYSTEM PROCESS 105 366 1.055e-09 2.273e-08
216 SINGLE ORGANISM CELL ADHESION 125 459 1.052e-09 2.273e-08
217 REGULATION OF MUSCLE SYSTEM PROCESS 66 195 1.067e-09 2.289e-08
218 REGULATION OF OSTEOBLAST DIFFERENTIATION 45 112 1.093e-09 2.333e-08
219 CELL PART MORPHOGENESIS 161 633 1.126e-09 2.393e-08
220 RESPONSE TO ALCOHOL 104 362 1.162e-09 2.457e-08
221 RESPONSE TO PEPTIDE 113 404 1.261e-09 2.632e-08
222 CEREBRAL CORTEX DEVELOPMENT 43 105 1.26e-09 2.632e-08
223 ODONTOGENESIS 43 105 1.26e-09 2.632e-08
224 OSSIFICATION 79 251 1.281e-09 2.662e-08
225 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 41 98 1.412e-09 2.92e-08
226 CELLULAR RESPONSE TO PEPTIDE 84 274 1.617e-09 3.329e-08
227 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 53 144 1.64e-09 3.361e-08
228 DIGESTIVE SYSTEM DEVELOPMENT 54 148 1.663e-09 3.394e-08
229 BONE DEVELOPMENT 56 156 1.681e-09 3.415e-08
230 CELL PROLIFERATION 168 672 1.922e-09 3.888e-08
231 CYTOSKELETON ORGANIZATION 201 838 2.005e-09 4.038e-08
232 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 41 99 2.034e-09 4.062e-08
233 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 41 99 2.034e-09 4.062e-08
234 CHEMICAL HOMEOSTASIS 208 874 2.086e-09 4.148e-08
235 REGULATION OF MEMBRANE POTENTIAL 99 343 2.215e-09 4.385e-08
236 REGULATION OF METAL ION TRANSPORT 95 325 2.282e-09 4.5e-08
237 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 249 1087 2.416e-09 4.744e-08
238 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 47 122 2.432e-09 4.754e-08
239 MUSCLE CONTRACTION 74 233 2.719e-09 5.293e-08
240 AMEBOIDAL TYPE CELL MIGRATION 55 154 2.897e-09 5.617e-08
241 REGULATION OF ORGAN MORPHOGENESIS 76 242 2.925e-09 5.647e-08
242 REGULATION OF CELL GROWTH 109 391 3.022e-09 5.811e-08
243 GLAND MORPHOGENESIS 40 97 3.701e-09 7.087e-08
244 REGULATION OF RESPONSE TO STRESS 320 1468 3.749e-09 7.149e-08
245 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 177 724 4.29e-09 8.147e-08
246 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 65 197 4.563e-09 8.589e-08
247 HOMEOSTATIC PROCESS 295 1337 4.578e-09 8.589e-08
248 REGULATION OF CELL SIZE 59 172 4.547e-09 8.589e-08
249 EPITHELIAL TO MESENCHYMAL TRANSITION 28 56 4.683e-09 8.715e-08
250 MUSCLE CELL DEVELOPMENT 48 128 4.678e-09 8.715e-08
251 CELL SUBSTRATE ADHESION 57 164 4.776e-09 8.819e-08
252 REPRODUCTIVE SYSTEM DEVELOPMENT 112 408 4.759e-09 8.819e-08
253 IMMUNE SYSTEM DEVELOPMENT 148 582 5.393e-09 9.918e-08
254 CELL ACTIVATION 145 568 5.879e-09 1.076e-07
255 RESPONSE TO EXTERNAL STIMULUS 384 1821 5.918e-09 1.076e-07
256 CELLULAR MACROMOLECULE LOCALIZATION 275 1234 5.903e-09 1.076e-07
257 APPENDAGE DEVELOPMENT 58 169 5.996e-09 1.081e-07
258 LIMB DEVELOPMENT 58 169 5.996e-09 1.081e-07
259 ACTOMYOSIN STRUCTURE ORGANIZATION 34 77 6.662e-09 1.194e-07
260 REGULATION OF VASCULATURE DEVELOPMENT 73 233 6.671e-09 1.194e-07
261 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 57 166 7.908e-09 1.41e-07
262 REGULATION OF TRANSMEMBRANE TRANSPORT 115 426 8.36e-09 1.485e-07
263 REGULATION OF BINDING 84 283 8.745e-09 1.547e-07
264 CARDIAC SEPTUM DEVELOPMENT 36 85 9.439e-09 1.664e-07
265 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 99 352 9.688e-09 1.701e-07
266 REGULATION OF JNK CASCADE 55 159 1.07e-08 1.872e-07
267 REGULATION OF HOMEOSTATIC PROCESS 119 447 1.102e-08 1.921e-07
268 HEAD MORPHOGENESIS 21 36 1.107e-08 1.923e-07
269 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 48 131 1.12e-08 1.938e-07
270 REGULATION OF CYTOPLASMIC TRANSPORT 126 481 1.163e-08 2.005e-07
271 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 31 68 1.208e-08 2.075e-07
272 REGULATION OF BODY FLUID LEVELS 131 506 1.293e-08 2.211e-07
273 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 110 406 1.419e-08 2.418e-07
274 INOSITOL LIPID MEDIATED SIGNALING 46 124 1.44e-08 2.446e-07
275 DENDRITE DEVELOPMENT 34 79 1.48e-08 2.504e-07
276 RESPONSE TO ABIOTIC STIMULUS 233 1024 1.487e-08 2.507e-07
277 ION TRANSPORT 278 1262 1.554e-08 2.61e-07
278 ACTIVATION OF MAPKK ACTIVITY 26 52 1.658e-08 2.776e-07
279 REGULATION OF ORGANELLE ORGANIZATION 262 1178 1.676e-08 2.796e-07
280 PLASMA MEMBRANE ORGANIZATION 65 203 1.724e-08 2.865e-07
281 PEPTIDYL TYROSINE MODIFICATION 61 186 1.736e-08 2.865e-07
282 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 29 62 1.734e-08 2.865e-07
283 HOMOPHILIC CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 53 153 1.86e-08 3.058e-07
284 PATTERN SPECIFICATION PROCESS 112 418 2.03e-08 3.326e-07
285 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 40 102 2.044e-08 3.338e-07
286 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 62 191 2.058e-08 3.346e-07
287 VESICLE MEDIATED TRANSPORT 273 1239 2.064e-08 3.346e-07
288 CARDIAC VENTRICLE DEVELOPMENT 41 106 2.177e-08 3.517e-07
289 REGULATION OF ENDOTHELIAL CELL MIGRATION 43 114 2.387e-08 3.843e-07
290 POSITIVE REGULATION OF OSSIFICATION 35 84 2.505e-08 4.019e-07
291 POSITIVE REGULATION OF PHOSPHOLIPASE ACTIVITY 26 53 2.754e-08 4.403e-07
292 REGULATION OF MUSCLE ORGAN DEVELOPMENT 40 103 2.822e-08 4.497e-07
293 RESPIRATORY SYSTEM DEVELOPMENT 63 197 2.996e-08 4.757e-07
294 RESPONSE TO INORGANIC SUBSTANCE 124 479 3.166e-08 5.011e-07
295 NEPHRON DEVELOPMENT 43 115 3.219e-08 5.077e-07
296 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 28 60 3.246e-08 5.102e-07
297 CELL GROWTH 48 135 3.379e-08 5.293e-07
298 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 39 100 3.655e-08 5.707e-07
299 REGULATION OF SECRETION 168 699 3.764e-08 5.857e-07
300 BODY MORPHOGENESIS 23 44 3.785e-08 5.871e-07
301 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 85 296 3.814e-08 5.896e-07
302 CARDIAC CHAMBER MORPHOGENESIS 40 104 3.873e-08 5.967e-07
303 ANTERIOR POSTERIOR PATTERN SPECIFICATION 62 194 3.949e-08 6.064e-07
304 REGULATION OF PHOSPHOLIPASE ACTIVITY 29 64 4.199e-08 6.427e-07
305 CARDIAC EPITHELIAL TO MESENCHYMAL TRANSITION 16 24 4.368e-08 6.664e-07
306 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 65 208 4.898e-08 7.448e-07
307 REGULATION OF INTRACELLULAR TRANSPORT 152 621 4.964e-08 7.524e-07
308 NEURAL CREST CELL DIFFERENTIATION 32 75 5.01e-08 7.568e-07
309 REGULATION OF EXTENT OF CELL GROWTH 39 101 5.028e-08 7.572e-07
310 NEURAL CREST CELL MIGRATION 25 51 5.184e-08 7.781e-07
311 CELL CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 64 204 5.256e-08 7.864e-07
312 REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 41 109 5.49e-08 8.188e-07
313 ESTABLISHMENT OR MAINTENANCE OF CELL POLARITY 49 141 5.62e-08 8.354e-07
314 MAMMARY GLAND DEVELOPMENT 43 117 5.764e-08 8.542e-07
315 DIGESTIVE TRACT MORPHOGENESIS 24 48 5.886e-08 8.694e-07
316 CELL FATE COMMITMENT 69 227 6.522e-08 9.603e-07
317 NEGATIVE REGULATION OF NEURON DEATH 56 171 6.95e-08 1.02e-06
318 CELLULAR RESPONSE TO INSULIN STIMULUS 50 146 7.047e-08 1.031e-06
319 REGULATION OF CATABOLIC PROCESS 173 731 7.332e-08 1.066e-06
320 RESPONSE TO MECHANICAL STIMULUS 65 210 7.325e-08 1.066e-06
321 NEGATIVE REGULATION OF KINASE ACTIVITY 74 250 7.443e-08 1.079e-06
322 NEGATIVE CHEMOTAXIS 21 39 7.536e-08 1.089e-06
323 REGULATION OF CHEMOTAXIS 58 180 7.757e-08 1.117e-06
324 POSITIVE REGULATION OF AXONOGENESIS 30 69 7.803e-08 1.117e-06
325 SYNAPSE ASSEMBLY 30 69 7.803e-08 1.117e-06
326 REGULATION OF WNT SIGNALING PATHWAY 87 310 8.318e-08 1.187e-06
327 REGULATION OF MUSCLE TISSUE DEVELOPMENT 39 103 9.346e-08 1.33e-06
328 IN UTERO EMBRYONIC DEVELOPMENT 87 311 9.737e-08 1.381e-06
329 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 24 49 9.764e-08 1.381e-06
330 RESPONSE TO CALCIUM ION 42 115 1.005e-07 1.417e-06
331 MULTICELLULAR ORGANISMAL SIGNALING 44 123 1.013e-07 1.423e-06
332 REGULATION OF STEM CELL PROLIFERATION 35 88 1.016e-07 1.424e-06
333 DEVELOPMENTAL CELL GROWTH 32 77 1.058e-07 1.478e-06
334 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 26 56 1.138e-07 1.581e-06
335 OUTFLOW TRACT MORPHOGENESIS 26 56 1.138e-07 1.581e-06
336 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 30 70 1.155e-07 1.599e-06
337 CELL CELL SIGNALING 179 767 1.218e-07 1.682e-06
338 EYE MORPHOGENESIS 47 136 1.26e-07 1.735e-06
339 FEMALE SEX DIFFERENTIATION 42 116 1.33e-07 1.826e-06
340 REGULATION OF CALCIUM ION TRANSPORT 64 209 1.427e-07 1.953e-06
341 NEGATIVE REGULATION OF MOLECULAR FUNCTION 238 1079 1.6e-07 2.184e-06
342 NEGATIVE REGULATION OF CELL ADHESION 67 223 1.635e-07 2.225e-06
343 REGULATION OF ION HOMEOSTASIS 62 201 1.665e-07 2.258e-06
344 CELL JUNCTION ASSEMBLY 45 129 1.699e-07 2.298e-06
345 PHOSPHATIDYLINOSITOL METABOLIC PROCESS 60 193 1.932e-07 2.606e-06
346 ENDOTHELIUM DEVELOPMENT 35 90 1.957e-07 2.624e-06
347 MESONEPHROS DEVELOPMENT 35 90 1.957e-07 2.624e-06
348 RESPONSE TO OXYGEN LEVELS 86 311 2.001e-07 2.675e-06
349 RESPONSE TO BMP 36 94 2.066e-07 2.746e-06
350 CELLULAR RESPONSE TO BMP STIMULUS 36 94 2.066e-07 2.746e-06
351 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 81 289 2.435e-07 3.228e-06
352 COLLAGEN FIBRIL ORGANIZATION 20 38 2.535e-07 3.351e-06
353 SECOND MESSENGER MEDIATED SIGNALING 52 160 2.637e-07 3.476e-06
354 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 51 156 2.784e-07 3.66e-06
355 LIPID PHOSPHORYLATION 37 99 2.906e-07 3.806e-06
356 REGULATION OF CELLULAR PROTEIN LOCALIZATION 135 552 2.912e-07 3.806e-06
357 LEUKOCYTE ACTIVATION 107 414 2.986e-07 3.891e-06
358 LIPID TRANSLOCATION 14 21 3.151e-07 4.096e-06
359 CRANIAL SKELETAL SYSTEM DEVELOPMENT 25 55 3.309e-07 4.289e-06
360 REGULATION OF ORGAN GROWTH 30 73 3.518e-07 4.546e-06
361 RESPONSE TO INSULIN 62 205 3.607e-07 4.65e-06
362 REGULATION OF NEURON APOPTOTIC PROCESS 59 192 3.781e-07 4.859e-06
363 CARDIOCYTE DIFFERENTIATION 36 96 3.8e-07 4.87e-06
364 NEGATIVE REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 28 66 3.91e-07 4.971e-06
365 NEGATIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 28 66 3.91e-07 4.971e-06
366 POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 37 100 3.897e-07 4.971e-06
367 IMMUNE SYSTEM PROCESS 401 1984 4.131e-07 5.237e-06
368 MUSCLE ORGAN MORPHOGENESIS 29 70 4.478e-07 5.662e-06
369 MEMBRANE DEPOLARIZATION DURING CARDIAC MUSCLE CELL ACTION POTENTIAL 11 14 4.521e-07 5.701e-06
370 REGULATION OF CARDIAC MUSCLE CELL CONTRACTION 16 27 4.737e-07 5.957e-06
371 PHOSPHATIDYLINOSITOL 3 PHOSPHATE BIOSYNTHETIC PROCESS 23 49 4.775e-07 5.958e-06
372 GLOMERULUS DEVELOPMENT 23 49 4.775e-07 5.958e-06
373 POST EMBRYONIC DEVELOPMENT 34 89 4.776e-07 5.958e-06
374 REGULATION OF CARTILAGE DEVELOPMENT 27 63 4.91e-07 6.093e-06
375 REGULATION OF MUSCLE ADAPTATION 27 63 4.91e-07 6.093e-06
376 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 35 93 4.966e-07 6.146e-06
377 CARDIAC MUSCLE CELL DIFFERENTIATION 30 74 5.003e-07 6.172e-06
378 EMBRYONIC EYE MORPHOGENESIS 18 33 5.014e-07 6.172e-06
379 REGULATION OF CYTOSKELETON ORGANIZATION 124 502 5.037e-07 6.184e-06
380 REGULATION OF RECEPTOR ACTIVITY 41 117 5.137e-07 6.29e-06
381 SEX DIFFERENTIATION 75 266 5.19e-07 6.339e-06
382 OVULATION CYCLE 40 113 5.207e-07 6.342e-06
383 EMBRYONIC CRANIAL SKELETON MORPHOGENESIS 22 46 5.635e-07 6.845e-06
384 PROTEIN LOCALIZATION TO CELL PERIPHERY 49 151 6.065e-07 7.35e-06
385 MAMMARY GLAND EPITHELIUM DEVELOPMENT 24 53 6.183e-07 7.472e-06
386 REGULATION OF HEART RATE 33 86 6.219e-07 7.496e-06
387 RESPONSE TO METAL ION 89 333 6.295e-07 7.569e-06
388 MORPHOGENESIS OF AN EPITHELIAL SHEET 21 43 6.55e-07 7.855e-06
389 EAR DEVELOPMENT 59 195 6.739e-07 8.061e-06
390 RESPONSE TO KETONE 56 182 7.055e-07 8.418e-06
391 REGULATION OF CELL SHAPE 46 139 7.093e-07 8.44e-06
392 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 45 135 7.425e-07 8.791e-06
393 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 45 135 7.425e-07 8.791e-06
394 ION HOMEOSTASIS 138 576 7.467e-07 8.819e-06
395 REGULATION OF MUSCLE CELL DIFFERENTIATION 49 152 7.556e-07 8.901e-06
396 BONE MORPHOGENESIS 31 79 7.616e-07 8.949e-06
397 REGIONALIZATION 84 311 8.057e-07 9.443e-06
398 REGULATION OF LIPASE ACTIVITY 32 83 8.09e-07 9.458e-06
399 ORGAN GROWTH 28 68 8.172e-07 9.507e-06
400 NERVE DEVELOPMENT 28 68 8.172e-07 9.507e-06
401 TISSUE REMODELING 33 87 8.469e-07 9.827e-06
402 ENSHEATHMENT OF NEURONS 34 91 8.754e-07 1.011e-05
403 AXON ENSHEATHMENT 34 91 8.754e-07 1.011e-05
404 REGULATION OF RESPONSE TO WOUNDING 105 413 8.918e-07 1.027e-05
405 CANONICAL WNT SIGNALING PATHWAY 35 95 8.948e-07 1.028e-05
406 PLATELET DERIVED GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 18 34 9.039e-07 1.033e-05
407 POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 18 34 9.039e-07 1.033e-05
408 PROTEIN UBIQUITINATION 148 629 9.194e-07 1.049e-05
409 VENTRICULAR SEPTUM DEVELOPMENT 24 54 9.422e-07 1.072e-05
410 POSITIVE REGULATION OF GROWTH 68 238 1.03e-06 1.169e-05
411 REGULATION OF NEURON DEATH 71 252 1.063e-06 1.203e-05
412 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 64 220 1.073e-06 1.211e-05
413 SKIN DEVELOPMENT 62 211 1.081e-06 1.218e-05
414 REGULATION OF DENDRITE DEVELOPMENT 41 120 1.099e-06 1.236e-05
415 LYMPHOCYTE ACTIVATION 90 342 1.122e-06 1.258e-05
416 EMBRYONIC PATTERN SPECIFICATION 25 58 1.135e-06 1.27e-05
417 ESTABLISHMENT OF CELL POLARITY 33 88 1.146e-06 1.278e-05
418 SKELETAL MUSCLE ORGAN DEVELOPMENT 45 137 1.178e-06 1.312e-05
419 POSITIVE REGULATION OF MAP KINASE ACTIVITY 61 207 1.183e-06 1.314e-05
420 FOREBRAIN CELL MIGRATION 26 62 1.32e-06 1.462e-05
421 REGULATION OF BMP SIGNALING PATHWAY 30 77 1.365e-06 1.509e-05
422 PROTEIN DEPHOSPHORYLATION 57 190 1.398e-06 1.542e-05
423 METANEPHROS DEVELOPMENT 31 81 1.44e-06 1.585e-05
424 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 40 117 1.452e-06 1.594e-05
425 DIVALENT INORGANIC CATION TRANSPORT 74 268 1.465e-06 1.604e-05
426 MODULATION OF SYNAPTIC TRANSMISSION 81 301 1.473e-06 1.609e-05
427 POSITIVE REGULATION OF LIPASE ACTIVITY 27 66 1.49e-06 1.619e-05
428 REGULATION OF CARDIAC MUSCLE CONTRACTION 27 66 1.49e-06 1.619e-05
429 HEART PROCESS 32 85 1.498e-06 1.625e-05
430 REGULATION OF VESICLE MEDIATED TRANSPORT 114 462 1.516e-06 1.641e-05
431 EPITHELIAL CELL DEVELOPMENT 56 186 1.521e-06 1.642e-05
432 EPITHELIAL CELL PROLIFERATION 33 89 1.539e-06 1.658e-05
433 ACTIN FILAMENT BASED MOVEMENT 34 93 1.564e-06 1.681e-05
434 CAMERA TYPE EYE MORPHOGENESIS 36 101 1.57e-06 1.683e-05
435 REGULATION OF ACTIN FILAMENT BASED MOVEMENT 17 32 1.709e-06 1.828e-05
436 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 42 126 1.713e-06 1.828e-05
437 MESODERM DEVELOPMENT 40 118 1.856e-06 1.976e-05
438 SOMITE DEVELOPMENT 30 78 1.876e-06 1.993e-05
439 NEURON MIGRATION 38 110 1.974e-06 2.092e-05
440 REGULATION OF PROTEIN IMPORT 55 183 1.994e-06 2.109e-05
441 CALCIUM MEDIATED SIGNALING 33 90 2.055e-06 2.16e-05
442 LEARNING 43 131 2.057e-06 2.16e-05
443 RENAL SYSTEM PROCESS 36 102 2.051e-06 2.16e-05
444 ACTION POTENTIAL 34 94 2.071e-06 2.171e-05
445 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 27 67 2.111e-06 2.203e-05
446 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 27 67 2.111e-06 2.203e-05
447 PERICARDIUM DEVELOPMENT 12 18 2.293e-06 2.387e-05
448 POSITIVE REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 19 39 2.339e-06 2.43e-05
449 CELLULAR RESPONSE TO ACID CHEMICAL 53 175 2.355e-06 2.441e-05
450 STEM CELL PROLIFERATION 25 60 2.42e-06 2.502e-05
451 RESPONSE TO ACID CHEMICAL 84 319 2.452e-06 2.53e-05
452 ESTABLISHMENT OF LOCALIZATION IN CELL 340 1676 2.465e-06 2.538e-05
453 REGULATION OF CELL DIVISION 74 272 2.663e-06 2.735e-05
454 REGULATION OF AUTOPHAGY 69 249 2.847e-06 2.918e-05
455 LEUKOCYTE DIFFERENTIATION 78 292 3.094e-06 3.164e-05
456 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 39 116 3.123e-06 3.187e-05
457 TRANSMEMBRANE TRANSPORT 234 1098 3.134e-06 3.191e-05
458 POSITIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 16 30 3.235e-06 3.28e-05
459 REGULATION OF HEART RATE BY CARDIAC CONDUCTION 16 30 3.235e-06 3.28e-05
460 EMBRYONIC CAMERA TYPE EYE MORPHOGENESIS 14 24 3.266e-06 3.289e-05
461 FACE DEVELOPMENT 22 50 3.265e-06 3.289e-05
462 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 156 684 3.261e-06 3.289e-05
463 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 66 236 3.304e-06 3.32e-05
464 REGULATION OF CATENIN IMPORT INTO NUCLEUS 15 27 3.349e-06 3.359e-05
465 MEMBRANE DEPOLARIZATION 25 61 3.472e-06 3.467e-05
466 POSITIVE REGULATION OF STEM CELL PROLIFERATION 25 61 3.472e-06 3.467e-05
467 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 140 602 3.513e-06 3.5e-05
468 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 31 84 3.544e-06 3.524e-05
469 REGULATION OF CATION CHANNEL ACTIVITY 32 88 3.587e-06 3.558e-05
470 METAL ION TRANSPORT 136 582 3.704e-06 3.667e-05
471 RETINA VASCULATURE DEVELOPMENT IN CAMERA TYPE EYE 11 16 3.942e-06 3.895e-05
472 CELLULAR HOMEOSTASIS 154 676 4.027e-06 3.97e-05
473 RESPONSE TO OXIDATIVE STRESS 90 352 4.087e-06 4.02e-05
474 REGULATION OF STEM CELL DIFFERENTIATION 38 113 4.13e-06 4.054e-05
475 REGULATION OF MEMBRANE LIPID DISTRIBUTION 18 37 4.427e-06 4.328e-05
476 CARDIAC MUSCLE CELL ACTION POTENTIAL 18 37 4.427e-06 4.328e-05
477 OSTEOBLAST DIFFERENTIATION 41 126 4.5e-06 4.38e-05
478 PROTEIN AUTOPHOSPHORYLATION 56 192 4.498e-06 4.38e-05
479 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 47 152 4.596e-06 4.465e-05
480 GLYCOPROTEIN METABOLIC PROCESS 90 353 4.625e-06 4.484e-05
481 SEGMENTATION 32 89 4.736e-06 4.581e-05
482 REGULATION OF MESENCHYMAL CELL PROLIFERATION 17 34 5.081e-06 4.905e-05
483 MESODERM MORPHOGENESIS 26 66 5.343e-06 5.126e-05
484 REGULATION OF CARDIAC CONDUCTION 26 66 5.343e-06 5.126e-05
485 LENS DEVELOPMENT IN CAMERA TYPE EYE 26 66 5.343e-06 5.126e-05
486 POSITIVE REGULATION OF CYTOSKELETON ORGANIZATION 52 175 5.397e-06 5.167e-05
487 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 61 216 5.442e-06 5.2e-05
488 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 27 70 5.678e-06 5.414e-05
489 CELLULAR LIPID METABOLIC PROCESS 198 913 5.79e-06 5.51e-05
490 MYELOID CELL DIFFERENTIATION 55 189 5.871e-06 5.575e-05
491 REGULATION OF MACROPHAGE DERIVED FOAM CELL DIFFERENTIATION 15 28 6.131e-06 5.798e-05
492 MUSCLE HYPERTROPHY 15 28 6.131e-06 5.798e-05
493 KIDNEY MORPHOGENESIS 30 82 6.207e-06 5.847e-05
494 CARDIAC CONDUCTION 30 82 6.207e-06 5.847e-05
495 RESPONSE TO CORTICOSTEROID 52 176 6.467e-06 6.079e-05
496 INSULIN LIKE GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 10 14 6.591e-06 6.183e-05
497 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 133 573 6.779e-06 6.337e-05
498 NEGATIVE REGULATION OF GROWTH 65 236 6.783e-06 6.337e-05
499 RESPONSE TO DRUG 105 431 7.079e-06 6.601e-05
500 SUBSTRATE ADHESION DEPENDENT CELL SPREADING 18 38 7.139e-06 6.643e-05
501 RESPONSE TO ESTROGEN 61 218 7.486e-06 6.939e-05
502 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 61 218 7.486e-06 6.939e-05
503 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 64 232 7.518e-06 6.954e-05
504 SPROUTING ANGIOGENESIS 20 45 7.532e-06 6.954e-05
505 POSITIVE REGULATION OF CHEMOTAXIS 39 120 7.863e-06 7.245e-05
506 CALCIUM ION TRANSPORT 62 223 7.911e-06 7.275e-05
507 ARTERY DEVELOPMENT 28 75 8.011e-06 7.309e-05
508 REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 28 75 8.011e-06 7.309e-05
509 ODONTOGENESIS OF DENTIN CONTAINING TOOTH 28 75 8.011e-06 7.309e-05
510 POSITIVE REGULATION OF AUTOPHAGY 28 75 8.011e-06 7.309e-05
511 SMAD PROTEIN SIGNAL TRANSDUCTION 23 56 8.111e-06 7.385e-05
512 DIVALENT INORGANIC CATION HOMEOSTASIS 87 343 8.214e-06 7.465e-05
513 GASTRULATION 47 155 8.254e-06 7.487e-05
514 CELLULAR CHEMICAL HOMEOSTASIS 132 570 8.278e-06 7.493e-05
515 EAR MORPHOGENESIS 37 112 8.741e-06 7.898e-05
516 CATION TRANSPORT 175 796 8.821e-06 7.954e-05
517 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 24 60 8.937e-06 8.043e-05
518 CARDIAC SEPTUM MORPHOGENESIS 21 49 9.015e-06 8.097e-05
519 STEROID HORMONE MEDIATED SIGNALING PATHWAY 40 125 9.219e-06 8.265e-05
520 DENDRITE MORPHOGENESIS 19 42 9.256e-06 8.282e-05
521 POSITIVE REGULATION OF PROTEIN IMPORT 35 104 9.561e-06 8.539e-05
522 PEPTIDYL TYROSINE DEPHOSPHORYLATION 34 100 9.927e-06 8.849e-05
523 REGULATION OF CELL JUNCTION ASSEMBLY 26 68 1.013e-05 9.016e-05
524 CYTOSOLIC CALCIUM ION TRANSPORT 22 53 1.036e-05 9.198e-05
525 POSITIVE REGULATION OF CATENIN IMPORT INTO NUCLEUS 9 12 1.054e-05 9.309e-05
526 EMBRYONIC CAMERA TYPE EYE FORMATION 9 12 1.054e-05 9.309e-05
527 INNER EAR MORPHOGENESIS 32 92 1.052e-05 9.309e-05
528 OVULATION CYCLE PROCESS 31 88 1.071e-05 9.44e-05
529 REGULATION OF CALCIUM MEDIATED SIGNALING 28 76 1.074e-05 9.443e-05
530 CARDIAC MUSCLE CELL CONTRACTION 15 29 1.08e-05 9.477e-05
531 POSITIVE REGULATION OF CATABOLIC PROCESS 97 395 1.1e-05 9.64e-05
532 NEGATIVE REGULATION OF CELL GROWTH 50 170 1.107e-05 9.68e-05
533 MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL 18 39 1.125e-05 9.793e-05
534 REGULATION OF AXON GUIDANCE 18 39 1.125e-05 9.793e-05
535 PEPTIDYL THREONINE MODIFICATION 20 46 1.13e-05 9.793e-05
536 REGULATION OF CHONDROCYTE DIFFERENTIATION 20 46 1.13e-05 9.793e-05
537 MELANOCYTE DIFFERENTIATION 12 20 1.129e-05 9.793e-05
538 CYCLIC NUCLEOTIDE METABOLIC PROCESS 23 57 1.152e-05 9.965e-05
539 REGULATION OF CARDIAC MUSCLE CONTRACTION BY CALCIUM ION SIGNALING 13 23 1.19e-05 0.0001027
540 HOMEOSTASIS OF NUMBER OF CELLS 51 175 1.204e-05 0.0001038
541 POSITIVE REGULATION OF CELL ADHESION 93 376 1.22e-05 0.000105
542 REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION 57 203 1.311e-05 0.0001125
543 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 21 50 1.318e-05 0.0001129
544 ESTABLISHMENT OF PROTEIN LOCALIZATION 289 1423 1.353e-05 0.0001157
545 POSITIVE REGULATION OF ION TRANSPORT 64 236 1.364e-05 0.0001165
546 CEREBRAL CORTEX CELL MIGRATION 19 43 1.407e-05 0.0001199
547 REGULATION OF PLASMA MEMBRANE ORGANIZATION 27 73 1.411e-05 0.0001201
548 FORMATION OF PRIMARY GERM LAYER 36 110 1.454e-05 0.0001234
549 MEMBRANE ORGANIZATION 193 899 1.458e-05 0.0001235
550 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 60 218 1.538e-05 0.0001301
551 NEGATIVE REGULATION OF MAPK CASCADE 44 145 1.547e-05 0.0001307
552 CELL MATRIX ADHESION 38 119 1.61e-05 0.0001357
553 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 33 98 1.675e-05 0.000141
554 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 37 115 1.714e-05 0.0001439
555 INTRACELLULAR RECEPTOR SIGNALING PATHWAY 49 168 1.726e-05 0.0001447
556 MAMMARY GLAND MORPHOGENESIS 18 40 1.737e-05 0.000145
557 NEGATIVE REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 18 40 1.737e-05 0.000145
558 NEURAL TUBE FORMATION 32 94 1.739e-05 0.000145
559 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 36 111 1.819e-05 0.0001514
560 PROTEIN CATABOLIC PROCESS 132 579 1.861e-05 0.0001546
561 RESPONSE TO ESTRADIOL 44 146 1.871e-05 0.0001549
562 ION TRANSMEMBRANE TRANSPORT 178 822 1.87e-05 0.0001549
563 REGULATION OF DENDRITE MORPHOGENESIS 27 74 1.882e-05 0.0001552
564 ACTIN MEDIATED CELL CONTRACTION 27 74 1.882e-05 0.0001552
565 REGULATION OF CELL PROJECTION ASSEMBLY 46 155 1.895e-05 0.000156
566 ANION TRANSPORT 118 507 1.931e-05 0.0001587
567 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 41 133 1.965e-05 0.0001612
568 VACUOLAR TRANSPORT 67 253 2.01e-05 0.0001646
569 REGULATION OF CALCIUM ION IMPORT 34 103 2.027e-05 0.0001657
570 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 14 27 2.056e-05 0.0001678
571 GLYCEROLIPID METABOLIC PROCESS 88 356 2.116e-05 0.0001724
572 CELL COMMUNICATION INVOLVED IN CARDIAC CONDUCTION 17 37 2.121e-05 0.0001725
573 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 33 99 2.126e-05 0.0001725
574 CYTOSKELETON DEPENDENT INTRACELLULAR TRANSPORT 37 116 2.127e-05 0.0001725
575 CHONDROCYTE DEVELOPMENT 12 21 2.244e-05 0.0001816
576 REGULATION OF MUSCLE CONTRACTION 44 147 2.256e-05 0.0001823
577 PEPTIDYL AMINO ACID MODIFICATION 181 841 2.308e-05 0.0001861
578 LEUKOCYTE MIGRATION 68 259 2.366e-05 0.0001905
579 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORT 20 48 2.427e-05 0.000195
580 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 38 121 2.454e-05 0.0001969
581 RESPONSE TO CYTOKINE 157 714 2.506e-05 0.0002007
582 CAMP METABOLIC PROCESS 16 34 2.555e-05 0.0002042
583 LIPID METABOLIC PROCESS 239 1158 2.582e-05 0.0002061
584 APOPTOTIC SIGNALING PATHWAY 74 289 2.673e-05 0.000213
585 LIMBIC SYSTEM DEVELOPMENT 33 100 2.684e-05 0.0002134
586 REGULATION OF DENDRITIC SPINE DEVELOPMENT 22 56 2.923e-05 0.0002321
587 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 45 153 2.972e-05 0.0002351
588 MULTI MULTICELLULAR ORGANISM PROCESS 58 213 2.967e-05 0.0002351
589 POSITIVE REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 15 31 3.024e-05 0.0002389
590 REGULATION OF GLUCOSE IMPORT 23 60 3.089e-05 0.0002432
591 CHONDROCYTE DIFFERENTIATION 23 60 3.089e-05 0.0002432
592 GOLGI ORGANIZATION 29 84 3.146e-05 0.0002473
593 INSULIN RECEPTOR SIGNALING PATHWAY 28 80 3.221e-05 0.0002527
594 NEURAL TUBE DEVELOPMENT 44 149 3.253e-05 0.0002545
595 REGULATION OF ACTION POTENTIAL 17 38 3.259e-05 0.0002545
596 MESENCHYME MORPHOGENESIS 17 38 3.259e-05 0.0002545
597 ENDOTHELIAL CELL DIFFERENTIATION 26 72 3.286e-05 0.0002561
598 REGULATION OF CARBOHYDRATE METABOLIC PROCESS 49 172 3.406e-05 0.000265
599 CARDIAC CELL DEVELOPMENT 20 49 3.479e-05 0.0002702
600 VENTRICULAR SEPTUM MORPHOGENESIS 14 28 3.498e-05 0.0002708
601 REGULATION OF FATTY ACID OXIDATION 14 28 3.498e-05 0.0002708
602 REGULATION OF ERK1 AND ERK2 CASCADE 63 238 3.547e-05 0.0002741
603 PROTEOLYSIS 247 1208 3.662e-05 0.0002826
604 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 118 514 3.674e-05 0.000283
605 RESPONSE TO REACTIVE OXYGEN SPECIES 53 191 3.684e-05 0.0002834
606 NEPHRON EPITHELIUM DEVELOPMENT 31 93 3.731e-05 0.0002864
607 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 21 53 3.796e-05 0.00029
608 NEURON PROJECTION EXTENSION 21 53 3.796e-05 0.00029
609 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 21 53 3.796e-05 0.00029
610 MAINTENANCE OF CELL NUMBER 40 132 3.82e-05 0.0002914
611 SYSTEM PROCESS 350 1785 3.834e-05 0.0002919
612 REGULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 13 25 3.922e-05 0.0002972
613 GLYCEROPHOSPHOLIPID METABOLIC PROCESS 75 297 3.915e-05 0.0002972
614 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL BY SARCOPLASMIC RETICULUM 13 25 3.922e-05 0.0002972
615 REGULATION OF FAT CELL DIFFERENTIATION 34 106 3.966e-05 0.0003001
616 CIRCADIAN REGULATION OF GENE EXPRESSION 22 57 4.036e-05 0.0003049
617 SINGLE ORGANISM CELLULAR LOCALIZATION 190 898 4.135e-05 0.0003118
618 REGULATION OF PHOSPHATASE ACTIVITY 39 128 4.146e-05 0.0003122
619 ACTIVIN RECEPTOR SIGNALING PATHWAY 12 22 4.208e-05 0.0003163
620 REGULATION OF CARDIAC MUSCLE CELL ACTION POTENTIAL 11 19 4.232e-05 0.0003176
621 REGULATION OF SODIUM ION TRANSPORT 27 77 4.264e-05 0.0003195
622 CELLULAR RESPONSE TO ALCOHOL 36 115 4.279e-05 0.0003201
623 PROTEIN LOCALIZATION TO VACUOLE 19 46 4.463e-05 0.0003334
624 LIPID LOCALIZATION 68 264 4.549e-05 0.0003392
625 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 70 274 4.699e-05 0.0003499
626 ACTIN FILAMENT ORGANIZATION 49 174 4.719e-05 0.0003507
627 PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 185 873 4.75e-05 0.000352
628 REGULATION OF CELL CYCLE 199 949 4.75e-05 0.000352
629 ENDOCARDIAL CUSHION DEVELOPMENT 15 32 4.841e-05 0.0003581
630 REGULATION OF PHOSPHOLIPASE C ACTIVITY 17 39 4.908e-05 0.000362
631 COCHLEA DEVELOPMENT 17 39 4.908e-05 0.000362
632 REGULATION OF SEQUESTERING OF CALCIUM ION 34 107 4.918e-05 0.0003621
633 REGULATION OF PROTEIN SECRETION 93 389 4.957e-05 0.0003644
634 CARDIAC MUSCLE TISSUE MORPHOGENESIS 21 54 5.268e-05 0.0003866
635 CELLULAR RESPONSE TO OXIDATIVE STRESS 51 184 5.28e-05 0.0003869
636 VESICLE ORGANIZATION 71 280 5.388e-05 0.0003942
637 RENAL TUBULE DEVELOPMENT 27 78 5.522e-05 0.0004034
638 RAS PROTEIN SIGNAL TRANSDUCTION 42 143 5.579e-05 0.0004062
639 NEGATIVE REGULATION OF INTRACELLULAR TRANSPORT 42 143 5.579e-05 0.0004062
640 CELL CELL JUNCTION ASSEMBLY 26 74 5.646e-05 0.0004105
641 SOMITOGENESIS 23 62 5.664e-05 0.0004111
642 REGULATION OF POLYSACCHARIDE METABOLIC PROCESS 18 43 5.704e-05 0.0004134
643 FOREBRAIN GENERATION OF NEURONS 24 66 5.728e-05 0.0004145
644 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 31 95 5.917e-05 0.0004275
645 POSITIVE REGULATION OF CELL GROWTH 43 148 6.062e-05 0.0004373
646 SEMAPHORIN PLEXIN SIGNALING PATHWAY 16 36 6.119e-05 0.0004407
647 DEPHOSPHORYLATION 72 286 6.145e-05 0.0004419
648 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 56 209 6.545e-05 0.00047
649 POSITIVE REGULATION OF SKELETAL MUSCLE TISSUE DEVELOPMENT 13 26 6.681e-05 0.0004782
650 NEGATIVE REGULATION OF EMBRYONIC DEVELOPMENT 13 26 6.681e-05 0.0004782
651 LOCOMOTORY BEHAVIOR 50 181 6.829e-05 0.0004881
652 HORMONE MEDIATED SIGNALING PATHWAY 45 158 7.018e-05 0.0004994
653 POSITIVE REGULATION OF FATTY ACID OXIDATION 9 14 7.019e-05 0.0004994
654 RESPONSE TO PURINE CONTAINING COMPOUND 45 158 7.018e-05 0.0004994
655 REGULATION OF STRIATED MUSCLE CONTRACTION 27 79 7.106e-05 0.000504
656 ERBB SIGNALING PATHWAY 27 79 7.106e-05 0.000504
657 EPIDERMAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 21 55 7.229e-05 0.0005112
658 REGULATION OF KIDNEY DEVELOPMENT 21 55 7.229e-05 0.0005112
659 NEGATIVE REGULATION OF BINDING 39 131 7.306e-05 0.0005158
660 REGULATION OF METANEPHROS DEVELOPMENT 12 23 7.501e-05 0.000528
661 INNERVATION 12 23 7.501e-05 0.000528
662 NEUROEPITHELIAL CELL DIFFERENTIATION 23 63 7.562e-05 0.0005315
663 SYNAPTIC SIGNALING 99 424 7.665e-05 0.0005379
664 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 36 118 7.801e-05 0.0005467
665 POSITIVE REGULATION OF BINDING 38 127 7.974e-05 0.0005579
666 CELLULAR RESPONSE TO EXTERNAL STIMULUS 67 264 8.371e-05 0.0005849
667 REGULATION OF EMBRYONIC DEVELOPMENT 35 114 8.453e-05 0.0005897
668 POSITIVE REGULATION OF MUSCLE CELL DIFFERENTIATION 28 84 8.698e-05 0.000605
669 TISSUE MIGRATION 28 84 8.698e-05 0.000605
670 POSITIVE REGULATION OF CELL DIVISION 39 132 8.767e-05 0.0006089
671 POSITIVE REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 19 48 8.936e-05 0.0006197
672 AXON EXTENSION 16 37 9.165e-05 0.0006346
673 NEGATIVE REGULATION OF CELL MATRIX ADHESION 14 30 9.185e-05 0.000635
674 POSITIVE REGULATION OF TRANSPORTER ACTIVITY 26 76 9.427e-05 0.0006508
675 CIRCADIAN RHYTHM 40 137 9.56e-05 0.000659
676 REGULATION OF DNA BINDING 30 93 9.802e-05 0.0006747
677 POSITIVE REGULATION OF CALCIUM ION TRANSPORT 33 106 9.863e-05 0.0006769
678 FAT CELL DIFFERENTIATION 33 106 9.863e-05 0.0006769
679 REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 22 60 9.985e-05 0.0006842
680 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 90 381 0.0001028 0.0007034
681 REGULATION OF MEMBRANE DEPOLARIZATION 17 41 0.0001053 0.0007194
682 NEGATIVE REGULATION OF AXON GUIDANCE 13 27 0.0001098 0.0007477
683 AXIS ELONGATION 13 27 0.0001098 0.0007477
684 HEMOSTASIS 76 311 0.0001109 0.0007542
685 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 56 213 0.0001139 0.0007737
686 FOREBRAIN NEURON DEVELOPMENT 15 34 0.0001149 0.0007787
687 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 38 129 0.000115 0.0007787
688 REGULATION OF JUN KINASE ACTIVITY 27 81 0.0001154 0.0007807
689 EXOCRINE SYSTEM DEVELOPMENT 18 45 0.0001161 0.0007826
690 ENDOCHONDRAL BONE MORPHOGENESIS 18 45 0.0001161 0.0007826
691 REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 26 77 0.0001206 0.0008121
692 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 70 282 0.0001226 0.0008241
693 RESPONSE TO FIBROBLAST GROWTH FACTOR 35 116 0.0001245 0.0008362
694 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 39 134 0.0001251 0.0008377
695 REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 25 73 0.0001251 0.0008377
696 REGULATION OF ODONTOGENESIS 12 24 0.0001279 0.0008551
697 REGULATION OF CIRCADIAN RHYTHM 32 103 0.0001303 0.0008688
698 STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 32 103 0.0001303 0.0008688
699 NEGATIVE REGULATION OF AXONOGENESIS 23 65 0.0001313 0.0008743
700 EPIDERMIS DEVELOPMENT 64 253 0.0001317 0.000875
701 MYOTUBE DIFFERENTIATION 21 57 0.0001318 0.000875
702 POSITIVE REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 16 38 0.0001346 0.0008897
703 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 16 38 0.0001346 0.0008897
704 POSITIVE REGULATION OF ORGAN GROWTH 16 38 0.0001346 0.0008897
705 PIGMENTATION 28 86 0.000138 0.0009105
706 EXTRINSIC APOPTOTIC SIGNALING PATHWAY 31 99 0.0001404 0.0009253
707 CELL AGGREGATION 11 21 0.0001438 0.0009453
708 CARTILAGE CONDENSATION 11 21 0.0001438 0.0009453
709 LIPID MODIFICATION 55 210 0.0001453 0.0009536
710 NEGATIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 39 135 0.0001488 0.000975
711 OLFACTORY BULB INTERNEURON DIFFERENTIATION 9 15 0.0001501 0.0009783
712 POSITIVE REGULATION OF MACROPHAGE DERIVED FOAM CELL DIFFERENTIATION 9 15 0.0001501 0.0009783
713 BLASTODERM SEGMENTATION 9 15 0.0001501 0.0009783
714 AUTONOMIC NERVOUS SYSTEM DEVELOPMENT 17 42 0.0001503 0.0009783
715 REGULATION OF HEART GROWTH 17 42 0.0001503 0.0009783
716 REGULATION OF WOUND HEALING 37 126 0.0001507 0.0009795
717 AGING 66 264 0.0001511 0.0009808
718 POSITIVE REGULATION OF SECRETION 87 370 0.000157 0.001017
719 CELL CYCLE ARREST 43 154 0.0001639 0.001058
720 POSITIVE REGULATION OF TRANSMEMBRANE TRANSPORT 38 131 0.0001637 0.001058
721 REGULATION OF SYNAPSE ORGANIZATION 34 113 0.0001639 0.001058
722 NEURAL PRECURSOR CELL PROLIFERATION 24 70 0.0001662 0.001071
723 REGULATION OF SKELETAL MUSCLE TISSUE DEVELOPMENT 19 50 0.0001697 0.001091
724 REGULATION OF ADHERENS JUNCTION ORGANIZATION 19 50 0.0001697 0.001091
725 SOMATIC STEM CELL POPULATION MAINTENANCE 23 66 0.000171 0.001097
726 EMBRYONIC CAMERA TYPE EYE DEVELOPMENT 15 35 0.0001711 0.001097
727 NEGATIVE REGULATION OF SYNAPTIC TRANSMISSION 22 62 0.0001742 0.001115
728 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 52 197 0.000176 0.001125
729 GLIAL CELL DIFFERENTIATION 39 136 0.0001764 0.001126
730 ANION TRANSMEMBRANE TRANSPORT 63 251 0.0001871 0.001193
731 TRABECULA MORPHOGENESIS 16 39 0.0001941 0.001235
732 POSITIVE REGULATION OF ENDOCYTOSIS 34 114 0.0001977 0.001257
733 REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 29 92 0.0001997 0.001268
734 EPITHELIAL TUBE BRANCHING INVOLVED IN LUNG MORPHOGENESIS 12 25 0.0002098 0.001326
735 MEMBRANE ASSEMBLY 12 25 0.0002098 0.001326
736 REGULATION OF TRANSFORMING GROWTH FACTOR BETA PRODUCTION 12 25 0.0002098 0.001326
737 INTRACELLULAR STEROID HORMONE RECEPTOR SIGNALING PATHWAY 24 71 0.0002128 0.001343
738 SECRETION 128 588 0.000213 0.001343
739 REGULATION OF LIPID METABOLIC PROCESS 69 282 0.000215 0.001353
740 REGULATION OF ORGAN FORMATION 14 32 0.0002158 0.001355
741 ADIPOSE TISSUE DEVELOPMENT 14 32 0.0002158 0.001355
742 GLIOGENESIS 47 175 0.0002284 0.001432
743 ARTERY MORPHOGENESIS 19 51 0.0002297 0.001439
744 REGULATION OF HORMONE LEVELS 107 478 0.000232 0.001451
745 PHOSPHOLIPID METABOLIC PROCESS 85 364 0.0002364 0.001476
746 LYMPHOCYTE DIFFERENTIATION 54 209 0.0002407 0.001501
747 NEGATIVE REGULATION OF VASCULATURE DEVELOPMENT 26 80 0.0002431 0.001514
748 POSITIVE REGULATION OF MYOBLAST DIFFERENTIATION 11 22 0.0002456 0.001522
749 PROTEIN LOCALIZATION TO CELL SURFACE 11 22 0.0002456 0.001522
750 SOMATIC STEM CELL DIVISION 11 22 0.0002456 0.001522
751 CELLULAR RESPONSE TO INTERLEUKIN 6 11 22 0.0002456 0.001522
752 REGULATION OF CELL ACTIVATION 108 484 0.0002467 0.001527
753 POSITIVE REGULATION OF WNT SIGNALING PATHWAY 42 152 0.0002483 0.001535
754 POSITIVE REGULATION OF AXON EXTENSION 15 36 0.0002496 0.00154
755 MULTICELLULAR ORGANISM GROWTH 25 76 0.0002573 0.001585
756 CELLULAR RESPONSE TO OXYGEN LEVELS 40 143 0.000261 0.001606
757 NEGATIVE REGULATION OF SECRETION 52 200 0.0002633 0.001618
758 REGULATION OF GENERATION OF PRECURSOR METABOLITES AND ENERGY 28 89 0.0002646 0.001624
759 STEM CELL DIVISION 13 29 0.0002696 0.001646
760 PIGMENT CELL DIFFERENTIATION 13 29 0.0002696 0.001646
761 POSITIVE REGULATION OF CARTILAGE DEVELOPMENT 13 29 0.0002696 0.001646
762 NEUROBLAST PROLIFERATION 13 29 0.0002696 0.001646
763 CELL CHEMOTAXIS 44 162 0.0002721 0.001655
764 PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 38 134 0.0002718 0.001655
765 NEGATIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 44 162 0.0002721 0.001655
766 POSITIVE REGULATION OF CELL MATRIX ADHESION 16 40 0.0002751 0.001669
767 NEGATIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 16 40 0.0002751 0.001669
768 REGULATION OF CARDIAC MUSCLE CONTRACTION BY REGULATION OF THE RELEASE OF SEQUESTERED CALCIUM ION 10 19 0.0002767 0.001677
769 MEMORY 30 98 0.0002779 0.001682
770 RELAXATION OF CARDIAC MUSCLE 8 13 0.0002819 0.001699
771 REGULATION OF CELL COMMUNICATION BY ELECTRICAL COUPLING 8 13 0.0002819 0.001699
772 MESENCHYMAL CELL PROLIFERATION 8 13 0.0002819 0.001699
773 RESPONSE TO ORGANOPHOSPHORUS 39 139 0.0002891 0.00174
774 CARDIAC MYOFIBRIL ASSEMBLY 9 16 0.0002938 0.001764
775 CELL SURFACE RECEPTOR SIGNALING PATHWAY INVOLVED IN HEART DEVELOPMENT 9 16 0.0002938 0.001764
776 RESPONSE TO AXON INJURY 18 48 0.0003032 0.001811
777 REGULATION OF DEPHOSPHORYLATION 43 158 0.0003026 0.001811
778 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO PLASMA MEMBRANE 18 48 0.0003032 0.001811
779 POSITIVE REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 18 48 0.0003032 0.001811
780 POSITIVE REGULATION OF REPRODUCTIVE PROCESS 19 52 0.0003075 0.001834
781 REGULATION OF NUCLEAR DIVISION 44 163 0.0003151 0.001877
782 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 76 321 0.0003165 0.001883
783 EMBRYONIC AXIS SPECIFICATION 14 33 0.0003193 0.001895
784 NEGATIVE REGULATION OF JNK CASCADE 14 33 0.0003193 0.001895
785 INORGANIC ION TRANSMEMBRANE TRANSPORT 126 583 0.0003236 0.001918
786 REPLACEMENT OSSIFICATION 12 26 0.0003323 0.001965
787 ENDOCHONDRAL OSSIFICATION 12 26 0.0003323 0.001965
788 CALCIUM ION TRANSMEMBRANE TRANSPORT 43 159 0.0003507 0.002071
789 ORGANELLE LOCALIZATION 94 415 0.0003542 0.002089
790 POSITIVE REGULATION OF CATION CHANNEL ACTIVITY 15 37 0.0003573 0.002102
791 REGULATION OF PROTEIN AUTOPHOSPHORYLATION 15 37 0.0003573 0.002102
792 REGULATION OF PROTEIN TARGETING 73 307 0.0003591 0.00211
793 GLYCOSYLATION 65 267 0.0003734 0.002191
794 CALCIUM ION IMPORT 22 65 0.0003766 0.002199
795 JNK CASCADE 26 82 0.0003766 0.002199
796 REGULATION OF CHEMOKINE PRODUCTION 22 65 0.0003766 0.002199
797 INTEGRIN MEDIATED SIGNALING PATHWAY 26 82 0.0003766 0.002199
798 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 16 41 0.0003839 0.00223
799 REGULATION OF VACUOLE ORGANIZATION 16 41 0.0003839 0.00223
800 ANDROGEN RECEPTOR SIGNALING PATHWAY 16 41 0.0003839 0.00223
801 LUNG ALVEOLUS DEVELOPMENT 16 41 0.0003839 0.00223
802 LUNG MORPHOGENESIS 17 45 4e-04 0.002321
803 ENDOTHELIAL CELL MIGRATION 20 57 0.0004012 0.002325
804 REGULATION OF DENDRITIC SPINE MORPHOGENESIS 13 30 0.0004056 0.002347
805 MESONEPHRIC TUBULE MORPHOGENESIS 19 53 0.0004072 0.002351
806 SKELETAL MUSCLE CELL DIFFERENTIATION 19 53 0.0004072 0.002351
807 RESPONSE TO HYDROGEN PEROXIDE 32 109 0.0004097 0.002362
808 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 24 74 0.0004293 0.002472
809 REGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS 27 87 0.0004309 0.002479
810 T CELL DIFFERENTIATION 35 123 0.0004328 0.002486
811 REACTIVE OXYGEN SPECIES METABOLIC PROCESS 29 96 0.0004457 0.002557
812 LYSOSOMAL TRANSPORT 23 70 0.000455 0.002607
813 POSITIVE REGULATION OF SODIUM ION TRANSPORT 14 34 0.0004623 0.002643
814 REGULATION OF AUTOPHAGOSOME ASSEMBLY 14 34 0.0004623 0.002643
815 REGENERATION 43 161 0.0004679 0.002671
816 REGULATION OF SMOOTH MUSCLE CELL DIFFERENTIATION 10 20 0.0004732 0.002692
817 REFLEX 10 20 0.0004732 0.002692
818 RELAXATION OF MUSCLE 10 20 0.0004732 0.002692
819 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 81 351 0.0004817 0.002737
820 ORGANIC HYDROXY COMPOUND METABOLIC PROCESS 106 482 0.0004884 0.002771
821 PROTEIN O LINKED GLYCOSYLATION 30 101 0.0004924 0.002791
822 NEGATIVE REGULATION OF AXON EXTENSION 15 38 0.0005025 0.002838
823 REGULATION OF SMOOTHENED SIGNALING PATHWAY 21 62 0.0005014 0.002838
824 REGULATION OF RENAL SYSTEM PROCESS 15 38 0.0005025 0.002838
825 POSITIVE REGULATION OF HEART GROWTH 12 27 0.0005103 0.002864
826 DEVELOPMENTAL INDUCTION 12 27 0.0005103 0.002864
827 HIPPO SIGNALING 12 27 0.0005103 0.002864
828 CALCIUM DEPENDENT CELL CELL ADHESION VIA PLASMA MEMBRANE CELL ADHESION MOLECULES 12 27 0.0005103 0.002864
829 REGULATION OF RYANODINE SENSITIVE CALCIUM RELEASE CHANNEL ACTIVITY 12 27 0.0005103 0.002864
830 CELLULAR GLUCAN METABOLIC PROCESS 20 58 0.00052 0.002911
831 GLUCAN METABOLIC PROCESS 20 58 0.00052 0.002911
832 LEUKOCYTE CELL CELL ADHESION 62 255 0.0005205 0.002911
833 CALCIUM ION TRANSMEMBRANE IMPORT INTO CYTOSOL 16 42 0.0005276 0.002919
834 REGULATION OF CYTOKINE PRODUCTION 121 563 0.0005273 0.002919
835 REGULATION OF COAGULATION 27 88 0.0005269 0.002919
836 REGULATION OF VENTRICULAR CARDIAC MUSCLE CELL ACTION POTENTIAL 7 11 0.0005265 0.002919
837 NEGATIVE REGULATION OF BMP SIGNALING PATHWAY 16 42 0.0005276 0.002919
838 REGULATION OF CELLULAR CARBOHYDRATE CATABOLIC PROCESS 16 42 0.0005276 0.002919
839 OLFACTORY BULB INTERNEURON DEVELOPMENT 7 11 0.0005265 0.002919
840 REGULATION OF CARBOHYDRATE CATABOLIC PROCESS 16 42 0.0005276 0.002919
841 CALCIUM ION IMPORT INTO CYTOSOL 16 42 0.0005276 0.002919
842 REGULATION OF EXOCYTOSIS 48 186 0.0005316 0.002937
843 REGULATION OF RECEPTOR BINDING 9 17 0.0005345 0.002938
844 CYCLIC NUCLEOTIDE CATABOLIC PROCESS 9 17 0.0005345 0.002938
845 REGULATION OF PROTEIN KINASE A SIGNALING 9 17 0.0005345 0.002938
846 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL 24 75 0.0005355 0.002938
847 REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 9 17 0.0005345 0.002938
848 MULTI ORGANISM BEHAVIOR 24 75 0.0005355 0.002938
849 REGULATION OF GLUCOSE METABOLIC PROCESS 31 106 0.000538 0.002949
850 POSITIVE REGULATION OF CATION TRANSMEMBRANE TRANSPORT 29 97 0.0005387 0.002949
851 REGULATION OF COENZYME METABOLIC PROCESS 18 50 0.0005409 0.002951
852 REGULATION OF COFACTOR METABOLIC PROCESS 18 50 0.0005409 0.002951
853 RHO PROTEIN SIGNAL TRANSDUCTION 18 50 0.0005409 0.002951
854 REGULATION OF ORGANELLE ASSEMBLY 40 148 0.0005602 0.003052
855 REGULATION OF GLOMERULUS DEVELOPMENT 8 14 0.0005642 0.003063
856 CAMP CATABOLIC PROCESS 8 14 0.0005642 0.003063
857 REGULATION OF CAMP DEPENDENT PROTEIN KINASE ACTIVITY 8 14 0.0005642 0.003063
858 POSITIVE REGULATION OF ERK1 AND ERK2 CASCADE 45 172 0.0005689 0.003085
859 INTERACTION WITH HOST 37 134 0.0005705 0.00309
860 ENDODERM DEVELOPMENT 23 71 0.000571 0.00309
861 TRANSCRIPTION INITIATION FROM RNA POLYMERASE II PROMOTER 41 153 0.0005813 0.003141
862 NEGATIVE REGULATION OF CELL ACTIVATION 42 158 0.0006008 0.003243
863 CELLULAR RESPONSE TO BIOTIC STIMULUS 43 163 0.0006187 0.003336
864 POSITIVE REGULATION OF NUCLEOSIDE METABOLIC PROCESS 11 24 0.0006339 0.00341
865 POSITIVE REGULATION OF ATP METABOLIC PROCESS 11 24 0.0006339 0.00341
866 BONE REMODELING 14 35 0.0006565 0.003527
867 SECRETION BY CELL 106 486 0.0006637 0.003562
868 CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS 48 188 0.0006862 0.003678
869 REGULATION OF POSTSYNAPTIC MEMBRANE POTENTIAL 19 55 0.0006929 0.003706
870 ACTIN CYTOSKELETON REORGANIZATION 19 55 0.0006929 0.003706
871 ERBB2 SIGNALING PATHWAY 15 39 0.0006953 0.003714
872 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 169 829 0.0007036 0.003755
873 ENERGY RESERVE METABOLIC PROCESS 23 72 0.000712 0.003795
874 REGULATION OF BLOOD PRESSURE 44 169 0.0007262 0.003866
875 NEGATIVE REGULATION OF CYTOPLASMIC TRANSPORT 33 117 0.0007366 0.003913
876 ORGANIC ANION TRANSPORT 87 387 0.0007365 0.003913
877 MAMMARY GLAND DUCT MORPHOGENESIS 12 28 0.0007622 0.004044
878 AXIS SPECIFICATION 27 90 0.0007765 0.004094
879 STRIATED MUSCLE CONTRACTION 29 99 0.0007769 0.004094
880 MIDBRAIN DEVELOPMENT 27 90 0.0007765 0.004094
881 SYMPATHETIC NERVOUS SYSTEM DEVELOPMENT 10 21 0.0007727 0.004094
882 REGULATION OF GLIOGENESIS 27 90 0.0007765 0.004094
883 ESTABLISHMENT OF PROTEIN LOCALIZATION TO PLASMA MEMBRANE 27 90 0.0007765 0.004094
884 NEGATIVE REGULATION OF TRANSPORTER ACTIVITY 21 64 0.0008071 0.004248
885 RESPONSE TO CAMP 30 104 0.0008411 0.004422
886 SALIVARY GLAND DEVELOPMENT 13 32 0.0008552 0.004476
887 BLOOD VESSEL REMODELING 13 32 0.0008552 0.004476
888 ESTABLISHMENT OF PROTEIN LOCALIZATION TO VACUOLE 13 32 0.0008552 0.004476
889 NEGATIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 13 32 0.0008552 0.004476
890 REGULATION OF NEUROTRANSMITTER LEVELS 48 190 0.0008796 0.004598
891 NEGATIVE REGULATION OF MAP KINASE ACTIVITY 23 73 0.0008822 0.004602
892 HIPPOCAMPUS DEVELOPMENT 23 73 0.0008822 0.004602
893 REGULATION OF ACTIN FILAMENT LENGTH 41 156 0.0008844 0.004608
894 NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 50 200 0.000895 0.004658
895 NEUROMUSCULAR JUNCTION DEVELOPMENT 14 36 0.0009154 0.004733
896 POSITIVE REGULATION OF MITOTIC CELL CYCLE 34 123 0.0009134 0.004733
897 REGULATION OF NUCLEOTIDE CATABOLIC PROCESS 14 36 0.0009154 0.004733
898 CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 14 36 0.0009154 0.004733
899 OLFACTORY LOBE DEVELOPMENT 14 36 0.0009154 0.004733
900 REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 14 36 0.0009154 0.004733
901 REGULATION OF GLUCOSE TRANSPORT 29 100 0.0009273 0.004789
902 PLATELET ACTIVATION 38 142 0.0009296 0.004796
903 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 17 48 0.000947 0.004855
904 REGULATION OF RESPONSE TO EXTRACELLULAR STIMULUS 44 171 0.0009436 0.004855
905 FORELIMB MORPHOGENESIS 15 40 0.0009473 0.004855
906 REGULATION OF RESPONSE TO NUTRIENT LEVELS 44 171 0.0009436 0.004855
907 MYOFIBRIL ASSEMBLY 17 48 0.000947 0.004855
908 DEVELOPMENTAL PIGMENTATION 15 40 0.0009473 0.004855
909 HEPATICOBILIARY SYSTEM DEVELOPMENT 35 128 0.0009577 0.004892
910 POSITIVE REGULATION OF LIPID METABOLIC PROCESS 35 128 0.0009577 0.004892
911 ENDOCRINE PROCESS 16 44 0.0009562 0.004892
912 LENS FIBER CELL DIFFERENTIATION 11 25 0.0009671 0.004934
913 REGULATION OF IMMUNE SYSTEM PROCESS 270 1403 0.0009832 0.005011
914 REGULATION OF CELL CELL ADHESION 85 380 0.0009862 0.005021
915 REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 21 65 0.001013 0.005149
916 MYELOID LEUKOCYTE DIFFERENTIATION 28 96 0.001021 0.005187
917 REGULATION OF FATTY ACID METABOLIC PROCESS 26 87 0.001025 0.005202
918 POSITIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 42 162 0.001035 0.005246
919 RESPONSE TO STIMULUS INVOLVED IN REGULATION OF MUSCLE ADAPTATION 8 15 0.001037 0.005252
920 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 82 365 0.001048 0.005301
921 MULTICELLULAR ORGANISMAL HOMEOSTASIS 64 272 0.001063 0.005368
922 EMBRYONIC DIGIT MORPHOGENESIS 20 61 0.001076 0.005431
923 NEGATIVE REGULATION OF DENDRITIC SPINE DEVELOPMENT 7 12 0.001087 0.005442
924 KERATINOCYTE PROLIFERATION 7 12 0.001087 0.005442
925 NEURON PROJECTION EXTENSION INVOLVED IN NEURON PROJECTION GUIDANCE 7 12 0.001087 0.005442
926 CARTILAGE MORPHOGENESIS 7 12 0.001087 0.005442
927 AXON EXTENSION INVOLVED IN AXON GUIDANCE 7 12 0.001087 0.005442
928 MECHANOSENSORY BEHAVIOR 7 12 0.001087 0.005442
929 MAMMARY GLAND EPITHELIAL CELL PROLIFERATION 7 12 0.001087 0.005442
930 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 12 29 0.00111 0.005547
931 REGULATION OF SYNAPTIC TRANSMISSION GABAERGIC 12 29 0.00111 0.005547
932 TUBE FORMATION 35 129 0.001113 0.005556
933 EMBRYONIC PLACENTA DEVELOPMENT 25 83 0.001121 0.005589
934 GOLGI VESICLE TRANSPORT 73 319 0.001133 0.005645
935 POSITIVE REGULATION OF FIBROBLAST PROLIFERATION 18 53 0.00119 0.005922
936 NEURON RECOGNITION 13 33 0.001204 0.005958
937 REGULATION OF PROTEIN BINDING 43 168 0.001199 0.005958
938 EMBRYONIC DIGESTIVE TRACT DEVELOPMENT 13 33 0.001204 0.005958
939 PROTEIN LOCALIZATION TO GOLGI APPARATUS 13 33 0.001204 0.005958
940 POSITIVE REGULATION OF FATTY ACID METABOLIC PROCESS 13 33 0.001204 0.005958
941 CELL CELL SIGNALING INVOLVED IN CARDIAC CONDUCTION 10 22 0.001212 0.005992
942 MULTICELLULAR ORGANISMAL MACROMOLECULE METABOLIC PROCESS 24 79 0.001222 0.006032
943 REGULATION OF SYNAPSE ASSEMBLY 24 79 0.001222 0.006032
944 MYELOID CELL HOMEOSTASIS 26 88 0.001234 0.006065
945 RESPONSE TO EXTRACELLULAR STIMULUS 96 441 0.001234 0.006065
946 POSITIVE REGULATION OF CHEMOKINE PRODUCTION 17 49 0.001234 0.006065
947 CELLULAR RESPONSE TO CALCIUM ION 17 49 0.001234 0.006065
948 NEGATIVE REGULATION OF GLIOGENESIS 14 37 0.001255 0.006129
949 HINDLIMB MORPHOGENESIS 14 37 0.001255 0.006129
950 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO CELL PERIPHERY 14 37 0.001255 0.006129
951 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 56 233 0.001255 0.006129
952 REGULATION OF MUSCLE HYPERTROPHY 14 37 0.001255 0.006129
953 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO PLASMA MEMBRANE 14 37 0.001255 0.006129
954 VENTRICULAR CARDIAC MUSCLE TISSUE DEVELOPMENT 16 45 0.001263 0.006154
955 POSITIVE REGULATION OF RECEPTOR ACTIVITY 16 45 0.001263 0.006154
956 POSITIVE REGULATION OF KIDNEY DEVELOPMENT 15 41 0.001272 0.006167
957 NEGATIVE REGULATION OF STRESS ACTIVATED MAPK CASCADE 15 41 0.001272 0.006167
958 CELL SUBSTRATE JUNCTION ASSEMBLY 15 41 0.001272 0.006167
959 NEGATIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 15 41 0.001272 0.006167
960 PROSTATE GLAND DEVELOPMENT 15 41 0.001272 0.006167
961 NEGATIVE REGULATION OF IMMUNE EFFECTOR PROCESS 29 102 0.001306 0.006322
962 ADULT BEHAVIOR 36 135 0.001335 0.006456
963 MULTICELLULAR ORGANISM METABOLIC PROCESS 27 93 0.001342 0.006485
964 REGULATION OF SYSTEMIC ARTERIAL BLOOD PRESSURE 25 84 0.001354 0.006513
965 CARDIAC VENTRICLE MORPHOGENESIS 20 62 0.00135 0.006513
966 FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 25 84 0.001354 0.006513
967 CYTOKINESIS 25 84 0.001354 0.006513
968 REGULATION OF APOPTOTIC SIGNALING PATHWAY 81 363 0.001375 0.006607
969 POSITIVE REGULATION OF CELL CYCLE 75 332 0.001425 0.006842
970 NEGATIVE REGULATION OF CARTILAGE DEVELOPMENT 11 26 0.001433 0.006858
971 RESPONSE TO INTERLEUKIN 6 11 26 0.001433 0.006858
972 REGULATION OF CELL FATE COMMITMENT 11 26 0.001433 0.006858
973 PHOSPHOLIPID TRANSPORT 19 58 0.001437 0.006863
974 O GLYCAN PROCESSING 19 58 0.001437 0.006863
975 INTRACELLULAR PROTEIN TRANSPORT 158 781 0.001444 0.006891
976 POLYSACCHARIDE METABOLIC PROCESS 24 80 0.001482 0.007065
977 LENS MORPHOGENESIS IN CAMERA TYPE EYE 9 19 0.001491 0.007085
978 RETINA DEVELOPMENT IN CAMERA TYPE EYE 35 131 0.00149 0.007085
979 POSITIVE REGULATION OF CHONDROCYTE DIFFERENTIATION 9 19 0.001491 0.007085
980 TRANSMISSION OF NERVE IMPULSE 18 54 0.001518 0.007208
981 MEMBRANE BIOGENESIS 12 30 0.001579 0.007491
982 POSITIVE REGULATION OF CYTOKINE PRODUCTION 82 370 0.001584 0.007505
983 CELLULAR RESPONSE TO CAMP 17 50 0.001591 0.007529
984 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 33 122 0.001603 0.007581
985 GLIAL CELL DEVELOPMENT 23 76 0.001619 0.007649
986 EPHRIN RECEPTOR SIGNALING PATHWAY 25 85 0.001627 0.007678
987 NEGATIVE REGULATION OF DNA BINDING 16 46 0.001649 0.007766
988 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 16 46 0.001649 0.007766
989 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 80 360 0.001655 0.007786
990 RENAL WATER HOMEOSTASIS 13 34 0.001662 0.007814
991 CELLULAR RESPONSE TO INORGANIC SUBSTANCE 40 156 0.001679 0.007884
992 NEGATIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 15 42 0.001686 0.007893
993 ENDOSOME TO LYSOSOME TRANSPORT 15 42 0.001686 0.007893
994 POSITIVE REGULATION OF GLUCOSE TRANSPORT 15 42 0.001686 0.007893
995 ENDOPLASMIC RETICULUM ORGANIZATION 14 38 0.001694 0.007923
996 RESPONSE TO TOXIC SUBSTANCE 57 241 0.001699 0.007937
997 MAMMARY GLAND EPITHELIAL CELL DIFFERENTIATION 8 16 0.001781 0.008189
998 EXTRACELLULAR MATRIX ASSEMBLY 8 16 0.001781 0.008189
999 MORPHOGENESIS OF AN ENDOTHELIUM 8 16 0.001781 0.008189
1000 NEGATIVE REGULATION OF NEUROTRANSMITTER TRANSPORT 8 16 0.001781 0.008189
1001 POSITIVE REGULATION OF PROTEIN SECRETION 51 211 0.001769 0.008189
1002 ORGAN INDUCTION 8 16 0.001781 0.008189
1003 NEURON CELL CELL ADHESION 8 16 0.001781 0.008189
1004 POSITIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA PRODUCTION 8 16 0.001781 0.008189
1005 SMOOTHENED SIGNALING PATHWAY 22 72 0.001765 0.008189
1006 PARAXIAL MESODERM DEVELOPMENT 8 16 0.001781 0.008189
1007 MAGNESIUM ION TRANSMEMBRANE TRANSPORT 8 16 0.001781 0.008189
1008 POSITIVE REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 8 16 0.001781 0.008189
1009 NEGATIVE REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 8 16 0.001781 0.008189
1010 ACTIVATION OF MAPK ACTIVITY 36 137 0.001765 0.008189
1011 BRANCHING INVOLVED IN SALIVARY GLAND MORPHOGENESIS 8 16 0.001781 0.008189
1012 REGULATION OF FATTY ACID BETA OXIDATION 8 16 0.001781 0.008189
1013 REGULATION OF HORMONE SECRETION 61 262 0.001792 0.00823
1014 POSITIVE REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 19 59 0.001802 0.008267
1015 POSITIVE REGULATION OF ERYTHROCYTE DIFFERENTIATION 10 23 0.001835 0.008395
1016 ESTABLISHMENT OF EPITHELIAL CELL POLARITY 10 23 0.001835 0.008395
1017 ADRENAL GLAND DEVELOPMENT 10 23 0.001835 0.008395
1018 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 82 372 0.001859 0.008496
1019 REGULATION OF NEUROLOGICAL SYSTEM PROCESS 21 68 0.001918 0.00876
1020 POSITIVE REGULATION OF RESPONSE TO WOUNDING 41 162 0.00193 0.008806
1021 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 25 86 0.001946 0.008867
1022 LIPID BIOSYNTHETIC PROCESS 113 539 0.001947 0.008867
1023 DIENCEPHALON DEVELOPMENT 23 77 0.00196 0.008917
1024 REGULATION OF VASCULOGENESIS 7 13 0.002025 0.00915
1025 TYPE B PANCREATIC CELL DEVELOPMENT 7 13 0.002025 0.00915
1026 MAGNESIUM ION TRANSPORT 7 13 0.002025 0.00915
1027 PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 7 13 0.002025 0.00915
1028 EYELID DEVELOPMENT IN CAMERA TYPE EYE 7 13 0.002025 0.00915
1029 SEMAPHORIN PLEXIN SIGNALING PATHWAY INVOLVED IN NEURON PROJECTION GUIDANCE 7 13 0.002025 0.00915
1030 REGULATION OF CELL FATE SPECIFICATION 7 13 0.002025 0.00915
1031 NEGATIVE REGULATION OF CHEMOTAXIS 17 51 0.002031 0.009165
1032 REGULATION OF ASTROCYTE DIFFERENTIATION 11 27 0.002067 0.009282
1033 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 11 27 0.002067 0.009282
1034 RESPONSE TO LITHIUM ION 11 27 0.002067 0.009282
1035 SUBSTRATE DEPENDENT CELL MIGRATION 11 27 0.002067 0.009282
1036 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER INVOLVED IN CELLULAR RESPONSE TO CHEMICAL STIMULUS 11 27 0.002067 0.009282
1037 REGULATION OF NEUROTRANSMITTER TRANSPORT 20 64 0.002078 0.009324
1038 PEPTIDYL SERINE MODIFICATION 38 148 0.002103 0.009426
1039 INTRA GOLGI VESICLE MEDIATED TRANSPORT 16 47 0.002129 0.009525
1040 NEURON DEATH 16 47 0.002129 0.009525
1041 POSITIVE REGULATION OF PROTEIN BINDING 22 73 0.002146 0.009573
1042 PANCREAS DEVELOPMENT 22 73 0.002146 0.009573
1043 CELLULAR RESPONSE TO KETONE 22 73 0.002146 0.009573
1044 VASCULAR PROCESS IN CIRCULATORY SYSTEM 41 163 0.002183 0.009728
1045 MITOTIC CYTOKINESIS 12 31 0.002201 0.009781
1046 CARDIAC ATRIUM DEVELOPMENT 12 31 0.002201 0.009781
1047 MULTIVESICULAR BODY ORGANIZATION 12 31 0.002201 0.009781
1048 CRANIAL NERVE DEVELOPMENT 15 43 0.002207 0.009797
1049 NEGATIVE REGULATION OF CATABOLIC PROCESS 49 203 0.002212 0.009813
1050 REPRODUCTION 248 1297 0.002219 0.009832
1051 DEVELOPMENTAL MATURATION 47 193 0.002225 0.009851
1052 REGULATION OF MONOOXYGENASE ACTIVITY 19 60 0.002242 0.009897
1053 ORGANELLE TRANSPORT ALONG MICROTUBULE 19 60 0.002242 0.009897
1054 MATERNAL PROCESS INVOLVED IN FEMALE PREGNANCY 19 60 0.002242 0.009897
1055 REGULATION OF GLYCOGEN METABOLIC PROCESS 13 35 0.002257 0.009916
1056 MEMBRANE PROTEIN PROTEOLYSIS 13 35 0.002257 0.009916
1057 RESPONSE TO MINERALOCORTICOID 13 35 0.002257 0.009916
1058 SPLEEN DEVELOPMENT 14 39 0.002254 0.009916
1059 CYTOSKELETON DEPENDENT CYTOKINESIS 14 39 0.002254 0.009916
NumGOOverlapSizeP ValueAdj. P Value
1 ENZYME BINDING 437 1737 8.503e-24 7.9e-21
2 MOLECULAR FUNCTION REGULATOR 350 1353 3.819e-21 1.774e-18
3 CYTOSKELETAL PROTEIN BINDING 226 819 2.984e-17 6.93e-15
4 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 185 629 2.78e-17 6.93e-15
5 REGULATORY REGION NUCLEIC ACID BINDING 225 818 5.257e-17 9.767e-15
6 RECEPTOR BINDING 358 1476 8.341e-17 1.291e-14
7 ACTIN BINDING 126 393 3.532e-15 3.413e-13
8 KINASE ACTIVITY 224 842 3.456e-15 3.413e-13
9 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 86 228 2.921e-15 3.413e-13
10 MACROMOLECULAR COMPLEX BINDING 336 1399 3.674e-15 3.413e-13
11 PROTEIN KINASE ACTIVITY 181 640 4.051e-15 3.421e-13
12 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 104 303 6.47e-15 4.624e-13
13 PROTEIN DOMAIN SPECIFIC BINDING 177 624 6.092e-15 4.624e-13
14 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 109 328 1.777e-14 1.179e-12
15 KINASE BINDING 170 606 6.227e-14 3.857e-12
16 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 291 1199 8.14e-14 4.593e-12
17 GROWTH FACTOR BINDING 55 123 8.406e-14 4.593e-12
18 RIBONUCLEOTIDE BINDING 415 1860 3.601e-13 1.858e-11
19 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 161 588 2.547e-12 1.245e-10
20 ENZYME ACTIVATOR ACTIVITY 135 471 4.735e-12 2.095e-10
21 ADENYL NUCLEOTIDE BINDING 344 1514 4.63e-12 2.095e-10
22 SMAD BINDING 37 72 5.568e-12 2.261e-10
23 PROTEIN COMPLEX BINDING 231 935 5.599e-12 2.261e-10
24 ZINC ION BINDING 274 1155 7.073e-12 2.738e-10
25 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 39 81 2.044e-11 7.304e-10
26 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 240 992 2.031e-11 7.304e-10
27 ENZYME REGULATOR ACTIVITY 233 959 2.625e-11 9.031e-10
28 NUCLEOSIDE TRIPHOSPHATASE REGULATOR ACTIVITY 100 329 7.967e-11 2.643e-09
29 CELL ADHESION MOLECULE BINDING 66 186 1.089e-10 3.489e-09
30 DOUBLE STRANDED DNA BINDING 191 764 1.461e-10 4.523e-09
31 CALCIUM ION BINDING 177 697 1.889e-10 5.661e-09
32 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 95 315 3.742e-10 1.086e-08
33 PROTEIN SERINE THREONINE KINASE ACTIVITY 123 445 5.291e-10 1.489e-08
34 TRANSITION METAL ION BINDING 311 1400 7.795e-10 2.13e-08
35 SEQUENCE SPECIFIC DNA BINDING 241 1037 1.11e-09 2.945e-08
36 IDENTICAL PROTEIN BINDING 272 1209 2.754e-09 7.106e-08
37 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 32 70 6.482e-09 1.628e-07
38 ACTIVATING TRANSCRIPTION FACTOR BINDING 28 57 7.782e-09 1.902e-07
39 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 57 168 1.293e-08 3.08e-07
40 UBIQUITIN LIKE PROTEIN TRANSFERASE ACTIVITY 113 420 1.375e-08 3.194e-07
41 PROTEIN DIMERIZATION ACTIVITY 256 1149 2.097e-08 4.75e-07
42 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 70 226 2.274e-08 5.031e-07
43 CALMODULIN BINDING 59 179 2.41e-08 5.206e-07
44 INTEGRIN BINDING 40 105 5.283e-08 1.115e-06
45 PDZ DOMAIN BINDING 36 90 5.642e-08 1.165e-06
46 PROTEIN TYROSINE KINASE ACTIVITY 57 176 8.221e-08 1.66e-06
47 BETA CATENIN BINDING 34 84 9.285e-08 1.835e-06
48 GTPASE BINDING 83 295 1.453e-07 2.812e-06
49 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 28 64 1.791e-07 3.396e-06
50 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC BINDING 35 90 1.957e-07 3.636e-06
51 PHOSPHOLIPID TRANSLOCATING ATPASE ACTIVITY 12 16 3.1e-07 5.643e-06
52 CORE PROMOTER PROXIMAL REGION DNA BINDING 98 371 3.159e-07 5.643e-06
53 TRANSCRIPTION COACTIVATOR ACTIVITY 82 296 3.509e-07 6.15e-06
54 RECEPTOR SIGNALING PROTEIN ACTIVITY 54 172 5.464e-07 9.4e-06
55 TRANSCRIPTION FACTOR BINDING 128 524 6.297e-07 1.064e-05
56 BINDING BRIDGING 54 173 6.704e-07 1.112e-05
57 GLYCOSAMINOGLYCAN BINDING 61 205 8.25e-07 1.345e-05
58 PHOSPHOLIPID BINDING 94 360 9.492e-07 1.52e-05
59 SH3 DOMAIN BINDING 40 116 1.131e-06 1.782e-05
60 GROWTH FACTOR RECEPTOR BINDING 43 129 1.296e-06 2.007e-05
61 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 37 105 1.555e-06 2.368e-05
62 X1 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 20 43 3.174e-06 4.743e-05
63 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 43 133 3.216e-06 4.743e-05
64 TRANSFORMING GROWTH FACTOR BETA BINDING 11 16 3.942e-06 5.722e-05
65 RHO GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 29 77 4.534e-06 6.48e-05
66 SULFUR COMPOUND BINDING 65 234 4.994e-06 7.029e-05
67 PROTEIN HOMODIMERIZATION ACTIVITY 162 722 5.744e-06 7.965e-05
68 SIGNALING ADAPTOR ACTIVITY 28 74 5.932e-06 8.104e-05
69 ION CHANNEL BINDING 37 111 6.925e-06 9.324e-05
70 PHOSPHORIC ESTER HYDROLASE ACTIVITY 92 368 8.601e-06 0.0001141
71 PROTEIN KINASE A BINDING 19 42 9.256e-06 0.0001211
72 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE ACTIVITY 11 17 9.524e-06 0.0001229
73 ATPASE ACTIVITY COUPLED TO MOVEMENT OF SUBSTANCES 39 121 9.805e-06 0.0001248
74 CHROMATIN BINDING 105 435 1.085e-05 0.0001362
75 LIPID BINDING 148 657 1.16e-05 0.0001436
76 HEPARIN BINDING 47 157 1.203e-05 0.0001451
77 TRANSCRIPTION COREPRESSOR ACTIVITY 61 221 1.192e-05 0.0001451
78 CORE PROMOTER SEQUENCE SPECIFIC DNA BINDING 34 101 1.265e-05 0.0001507
79 RAB GTPASE BINDING 38 120 1.991e-05 0.0002324
80 PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 51 178 2.01e-05 0.0002324
81 PROTEIN TYROSINE PHOSPHATASE ACTIVITY 34 103 2.027e-05 0.0002324
82 CORE PROMOTER BINDING 45 152 2.483e-05 0.0002779
83 ACTIN FILAMENT BINDING 38 121 2.454e-05 0.0002779
84 PHOSPHATASE BINDING 47 162 2.944e-05 0.0003255
85 WNT PROTEIN BINDING 15 31 3.024e-05 0.0003267
86 UBIQUITIN LIKE PROTEIN LIGASE ACTIVITY 55 199 3e-05 0.0003267
87 PROTEIN HETERODIMERIZATION ACTIVITY 109 468 3.824e-05 0.0004036
88 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II ACTIVATING TRANSCRIPTION FACTOR BINDING 21 53 3.796e-05 0.0004036
89 NITRIC OXIDE SYNTHASE BINDING 11 19 4.232e-05 0.0004418
90 PROTEIN PHOSPHATASE BINDING 37 120 4.86e-05 0.0005017
91 PLATELET DERIVED GROWTH FACTOR BINDING 8 11 4.918e-05 0.0005021
92 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 29 86 5.163e-05 0.0005214
93 PROTEIN TYROSINE KINASE BINDING 21 54 5.268e-05 0.0005263
94 ACTININ BINDING 14 29 5.755e-05 0.0005688
95 RNA POLYMERASE II ACTIVATING TRANSCRIPTION FACTOR BINDING 16 36 6.119e-05 0.000586
96 RNA POLYMERASE II TRANSCRIPTION COACTIVATOR ACTIVITY 16 36 6.119e-05 0.000586
97 FRIZZLED BINDING 16 36 6.119e-05 0.000586
98 TRANSMEMBRANE TRANSPORTER ACTIVITY 207 997 6.239e-05 0.0005914
99 PHOSPHATIDYLINOSITOL KINASE ACTIVITY 20 51 6.867e-05 0.0006444
100 PHOSPHATIDYLINOSITOL BINDING 54 200 7.018e-05 0.000652
101 HYDROLASE ACTIVITY ACTING ON ACID ANHYDRIDES 174 820 7.357e-05 0.0006767
102 CYTOKINE BINDING 30 92 7.843e-05 0.0007143
103 PHOSPHOLIPID TRANSPORTER ACTIVITY 19 48 8.936e-05 0.000806
104 METALLOPEPTIDASE ACTIVITY 51 188 9.647e-05 0.0008617
105 TRANSPORTER ACTIVITY 256 1276 9.941e-05 0.0008795
106 KINASE INHIBITOR ACTIVITY 29 89 0.000104 0.0009115
107 CHEMOREPELLENT ACTIVITY 13 27 0.0001098 0.0009529
108 PROTEIN TYROSINE SERINE THREONINE PHOSPHATASE ACTIVITY 18 45 0.0001161 0.0009983
109 GAMMA CATENIN BINDING 8 12 0.0001265 0.001078
110 COLLAGEN BINDING 23 65 0.0001313 0.001109
111 ALPHA ACTININ BINDING 11 21 0.0001438 0.001204
112 X3 5 CYCLIC AMP PHOSPHODIESTERASE ACTIVITY 9 15 0.0001501 0.001245
113 RHO GTPASE BINDING 26 78 0.0001533 0.00126
114 METAL ION TRANSMEMBRANE TRANSPORTER ACTIVITY 96 417 0.0001683 0.001372
115 PHOSPHATASE REGULATOR ACTIVITY 28 87 0.0001723 0.001392
116 HISTONE ACETYLTRANSFERASE BINDING 13 28 0.0001746 0.001398
117 RECEPTOR SIGNALING PROTEIN SERINE THREONINE KINASE ACTIVITY 29 92 0.0001997 0.001586
118 CYCLIC NUCLEOTIDE BINDING 15 36 0.0002496 0.001965
119 PROTEIN KINASE A REGULATORY SUBUNIT BINDING 9 16 0.0002938 0.002293
120 PHOSPHATASE ACTIVITY 67 275 0.0002993 0.002317
121 CHANNEL REGULATOR ACTIVITY 37 131 0.0003541 0.002719
122 METALLOENDOPEPTIDASE ACTIVITY 33 113 0.0003731 0.002825
123 RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 31 104 0.0003741 0.002825
124 R SMAD BINDING 11 23 0.000402 0.00299
125 GROWTH FACTOR ACTIVITY 43 160 0.0004056 0.00299
126 ATPASE ACTIVITY 96 427 0.0004043 0.00299
127 TUBULIN BINDING 66 273 0.000415 0.003036
128 CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 132 622 0.0005199 0.003773
129 KINASE REGULATOR ACTIVITY 48 186 0.0005316 0.003799
130 PROTEIN C TERMINUS BINDING 48 186 0.0005316 0.003799
131 DIVALENT INORGANIC CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 44 167 0.0005544 0.003917
132 MICROTUBULE BINDING 51 201 0.0005565 0.003917
133 ENHANCER BINDING 28 93 0.0005882 0.004109
134 LIGASE ACTIVITY 91 406 0.000625 0.004333
135 UBIQUITIN LIKE PROTEIN BINDING 34 121 0.000665 0.004531
136 EXTRACELLULAR MATRIX STRUCTURAL CONSTITUENT 24 76 0.0006639 0.004531
137 MYOSIN BINDING 20 59 0.0006682 0.004531
138 ANDROGEN RECEPTOR BINDING 15 39 0.0006953 0.00468
139 BHLH TRANSCRIPTION FACTOR BINDING 12 28 0.0007622 0.005094
140 SH3 SH2 ADAPTOR ACTIVITY 18 52 0.0009242 0.006132
141 RNA POLYMERASE II TRANSCRIPTION COFACTOR ACTIVITY 27 91 0.000936 0.006167
142 TRANSCRIPTION FACTOR ACTIVITY DIRECT LIGAND REGULATED SEQUENCE SPECIFIC DNA BINDING 17 48 0.000947 0.006196
143 NADP BINDING 16 44 0.0009562 0.006212
144 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ACTIVITY 11 25 0.0009671 0.006239
145 GABA RECEPTOR BINDING 8 15 0.001037 0.006646
146 GLYCOPROTEIN BINDING 29 101 0.001102 0.007015
147 GATED CHANNEL ACTIVITY 74 325 0.001218 0.007646
148 WNT ACTIVATED RECEPTOR ACTIVITY 10 22 0.001212 0.007646
149 STRUCTURAL CONSTITUENT OF MUSCLE 15 41 0.001272 0.007934
150 PHOSPHATIDYLINOSITOL PHOSPHATE BINDING 32 116 0.001319 0.008166
151 PHOSPHOLIPASE BINDING 9 19 0.001491 0.009051
152 POLYPEPTIDE N ACETYLGALACTOSAMINYLTRANSFERASE ACTIVITY 9 19 0.001491 0.009051
153 CYTOKINE RECEPTOR ACTIVITY 26 89 0.001479 0.009051
154 EPIDERMAL GROWTH FACTOR RECEPTOR BINDING 12 30 0.001579 0.009466
155 PROTEIN SERINE THREONINE KINASE INHIBITOR ACTIVITY 12 30 0.001579 0.009466
156 TRANSFORMING GROWTH FACTOR BETA RECEPTOR BINDING 17 50 0.001591 0.009473
157 E BOX BINDING 13 34 0.001662 0.009713
158 UBIQUITIN LIKE PROTEIN CONJUGATING ENZYME BINDING 13 34 0.001662 0.009713
159 PHOSPHATIDYLINOSITOL 3 4 5 TRISPHOSPHATE BINDING 13 34 0.001662 0.009713
160 CORECEPTOR ACTIVITY 14 38 0.001694 0.009837
NumGOOverlapSizeP ValueAdj. P Value
1 CELL JUNCTION 329 1151 9.537e-28 5.57e-25
2 NEURON PROJECTION 266 942 1.136e-21 3.318e-19
3 NEURON PART 333 1265 1.973e-21 3.84e-19
4 SYNAPSE 221 754 3.004e-20 4.386e-18
5 CELL PROJECTION 431 1786 8.886e-20 1.038e-17
6 MEMBRANE REGION 299 1134 2.149e-19 2.092e-17
7 ANCHORING JUNCTION 158 489 4.515e-19 3.767e-17
8 PLASMA MEMBRANE REGION 249 929 3.326e-17 2.428e-15
9 PROTEINACEOUS EXTRACELLULAR MATRIX 120 356 2.528e-16 1.476e-14
10 GOLGI APPARATUS 350 1445 2.407e-16 1.476e-14
11 CELL SUBSTRATE JUNCTION 128 398 1.629e-15 8.651e-14
12 POSTSYNAPSE 123 378 2.196e-15 1.035e-13
13 EXTRACELLULAR MATRIX COMPONENT 58 125 2.305e-15 1.035e-13
14 EXTRACELLULAR MATRIX 134 426 2.541e-15 1.06e-13
15 CELL CELL JUNCTION 123 383 6.569e-15 2.557e-13
16 SYNAPSE PART 171 610 5.617e-14 2.05e-12
17 CELL LEADING EDGE 112 350 1.401e-13 4.811e-12
18 EXCITATORY SYNAPSE 74 197 3.174e-13 1.03e-11
19 ACTIN CYTOSKELETON 132 444 4.615e-13 1.418e-11
20 SOMATODENDRITIC COMPARTMENT 176 650 6.847e-13 1.999e-11
21 INTRINSIC COMPONENT OF PLASMA MEMBRANE 372 1649 1.542e-12 4.287e-11
22 CONTRACTILE FIBER 74 211 1.572e-11 4.174e-10
23 VACUOLE 276 1180 3.024e-11 7.678e-10
24 I BAND 50 121 3.957e-11 9.629e-10
25 INTRACELLULAR VESICLE 288 1259 1.429e-10 3.339e-09
26 ENDOSOME 196 793 2.344e-10 5.265e-09
27 RECEPTOR COMPLEX 98 327 2.905e-10 6.282e-09
28 DENDRITE 125 451 3.171e-10 6.614e-09
29 CYTOPLASMIC REGION 88 287 6.596e-10 1.328e-08
30 BASEMENT MEMBRANE 40 93 8.306e-10 1.617e-08
31 GOLGI APPARATUS PART 213 893 1.081e-09 2.036e-08
32 INTERCALATED DISC 27 51 1.718e-09 3.136e-08
33 CELL CELL CONTACT ZONE 31 64 1.921e-09 3.4e-08
34 CYTOSKELETON 412 1967 3.625e-09 6.226e-08
35 APICAL JUNCTION COMPLEX 48 128 4.678e-09 7.805e-08
36 PLASMA MEMBRANE PROTEIN COMPLEX 133 510 6.18e-09 1.003e-07
37 CELL PROJECTION PART 219 946 9.33e-09 1.473e-07
38 PERINUCLEAR REGION OF CYTOPLASM 158 642 1.832e-08 2.808e-07
39 SITE OF POLARIZED GROWTH 52 149 1.899e-08 2.808e-07
40 SARCOLEMMA 46 125 1.923e-08 2.808e-07
41 AXON 112 418 2.03e-08 2.892e-07
42 CELL CORTEX 72 238 4.225e-08 5.874e-07
43 PLASMA MEMBRANE RAFT 35 86 5.125e-08 6.96e-07
44 CELL SURFACE 178 757 7.642e-08 1.014e-06
45 LAMELLIPODIUM 56 172 8.694e-08 1.128e-06
46 MEMBRANE MICRODOMAIN 82 288 9.875e-08 1.254e-06
47 EXTRINSIC COMPONENT OF MEMBRANE 74 252 1.063e-07 1.293e-06
48 SYNAPTIC MEMBRANE 76 261 1.054e-07 1.293e-06
49 POSTSYNAPTIC MEMBRANE 63 205 1.542e-07 1.838e-06
50 GOLGI MEMBRANE 165 703 2.595e-07 3.03e-06
51 CELL BODY 123 494 3.567e-07 4.085e-06
52 ORGANELLE SUBCOMPARTMENT 85 311 4.047e-07 4.545e-06
53 FILOPODIUM 35 94 6.687e-07 7.368e-06
54 RUFFLE 50 156 7.112e-07 7.692e-06
55 VACUOLAR PART 161 694 7.755e-07 8.234e-06
56 BASOLATERAL PLASMA MEMBRANE 62 211 1.081e-06 1.128e-05
57 COMPLEX OF COLLAGEN TRIMERS 14 23 1.6e-06 1.64e-05
58 VESICLE MEMBRANE 123 512 2.552e-06 2.569e-05
59 ACTIN BASED CELL PROJECTION 54 181 3.146e-06 3.114e-05
60 ENDOPLASMIC RETICULUM 331 1631 3.273e-06 3.186e-05
61 VACUOLAR MEMBRANE 137 587 3.657e-06 3.501e-05
62 NEURON SPINE 40 121 3.778e-06 3.559e-05
63 ACTOMYOSIN 25 62 4.926e-06 4.567e-05
64 A BAND 17 34 5.081e-06 4.636e-05
65 MEMBRANE PROTEIN COMPLEX 218 1020 5.602e-06 5.033e-05
66 T TUBULE 20 45 7.532e-06 6.665e-05
67 AXON PART 61 219 8.757e-06 7.633e-05
68 APICAL PART OF CELL 90 361 1.204e-05 0.0001034
69 ENDOSOMAL PART 103 430 1.845e-05 0.0001561
70 CYTOPLASMIC VESICLE PART 136 601 2.056e-05 0.0001716
71 M BAND 12 21 2.244e-05 0.0001846
72 COLLAGEN TRIMER 30 88 3.051e-05 0.0002474
73 NEURONAL POSTSYNAPTIC DENSITY 21 53 3.796e-05 0.0003037
74 SIDE OF MEMBRANE 101 428 4.194e-05 0.000331
75 LATERAL PLASMA MEMBRANE 20 50 4.919e-05 0.000383
76 TRANS GOLGI NETWORK 53 193 5.003e-05 0.0003845
77 CYTOPLASMIC SIDE OF MEMBRANE 48 170 5.215e-05 0.0003955
78 PLASMA MEMBRANE RECEPTOR COMPLEX 49 175 5.536e-05 0.0004062
79 LEADING EDGE MEMBRANE 40 134 5.565e-05 0.0004062
80 MAIN AXON 22 58 5.514e-05 0.0004062
81 ACTIN FILAMENT 25 70 5.718e-05 0.0004123
82 VOLTAGE GATED SODIUM CHANNEL COMPLEX 9 14 7.019e-05 0.0004999
83 TRANSPORTER COMPLEX 78 321 0.0001106 0.0007783
84 PARANODE REGION OF AXON 8 12 0.0001265 0.0008688
85 BANDED COLLAGEN FIBRIL 8 12 0.0001265 0.0008688
86 SARCOPLASMIC RETICULUM MEMBRANE 16 38 0.0001346 0.0009141
87 TRANSCRIPTION FACTOR COMPLEX 73 298 0.0001382 0.0009278
88 RUFFLE MEMBRANE 26 80 0.0002431 0.001613
89 SARCOPLASM 23 68 0.000283 0.001857
90 PHOSPHATASE COMPLEX 18 48 0.0003032 0.001968
91 PROTEIN KINASE COMPLEX 28 90 0.0003254 0.002088
92 DESMOSOME 12 26 0.0003323 0.002109
93 ACTIN FILAMENT BUNDLE 20 57 0.0004012 0.002492
94 LATE ENDOSOME 54 213 0.0003987 0.002492
95 AXONAL GROWTH CONE 10 20 0.0004732 0.002909
96 WNT SIGNALOSOME 7 11 0.0005265 0.003203
97 SODIUM CHANNEL COMPLEX 9 17 0.0005345 0.003218
98 FIBRIL 8 14 0.0005642 0.003362
99 MICROTUBULE 91 405 0.0005748 0.003391
100 APICAL PLASMA MEMBRANE 69 292 0.0006151 0.003592
101 TRANSFERASE COMPLEX 146 703 0.0007163 0.004142
102 RECYCLING ENDOSOME 36 131 0.0007394 0.004233
103 GLYCOPROTEIN COMPLEX 10 21 0.0007727 0.004381
104 FILOPODIUM MEMBRANE 9 18 0.0009157 0.005142
105 ENDOCYTIC VESICLE 61 256 0.0009871 0.00549
106 CELL CORTEX PART 33 119 0.001015 0.005591
107 TRANSCRIPTIONAL REPRESSOR COMPLEX 23 74 0.001086 0.00593
108 PML BODY 28 97 0.001217 0.006581
109 CATALYTIC COMPLEX 204 1038 0.001452 0.007711
110 EARLY ENDOSOME 69 301 0.00145 0.007711
111 ENDOPLASMIC RETICULUM PART 226 1163 0.00151 0.007799
112 COSTAMERE 9 19 0.001491 0.007799
113 CELL CELL ADHERENS JUNCTION 18 54 0.001518 0.007799
114 TRANSPORT VESICLE 76 338 0.001522 0.007799
115 EXTRINSIC COMPONENT OF PLASMA MEMBRANE 36 136 0.001537 0.007806
116 UBIQUITIN LIGASE COMPLEX 61 262 0.001792 0.008944
117 ENDOPLASMIC RETICULUM LUMEN 49 201 0.001778 0.008944
118 CLATHRIN COATED VESICLE 40 157 0.001907 0.009437
119 CATION CHANNEL COMPLEX 42 167 0.00195 0.009568

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 MAPK_signaling_pathway_hsa04010 104 295 8.36e-16 4.347e-14
2 Focal_adhesion_hsa04510 78 199 4.939e-15 1.284e-13
3 Rap1_signaling_pathway_hsa04015 75 206 1.378e-12 2.389e-11
4 FoxO_signaling_pathway_hsa04068 54 132 1.064e-11 1.383e-10
5 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 55 139 3.261e-11 3.392e-10
6 Ras_signaling_pathway_hsa04014 78 232 4.87e-11 4.22e-10
7 Regulation_of_actin_cytoskeleton_hsa04810 72 208 5.892e-11 4.377e-10
8 TGF_beta_signaling_pathway_hsa04350 39 84 8.256e-11 5.289e-10
9 PI3K_Akt_signaling_pathway_hsa04151 105 352 9.154e-11 5.289e-10
10 cGMP_PKG_signaling_pathway_hsa04022 59 163 4.281e-10 2.226e-09
11 Wnt_signaling_pathway_hsa04310 54 146 9.391e-10 4.439e-09
12 Hippo_signaling_pathway_hsa04390 55 154 2.897e-09 1.256e-08
13 cAMP_signaling_pathway_hsa04024 64 198 1.474e-08 5.634e-08
14 Adherens_junction_hsa04520 32 72 1.517e-08 5.634e-08
15 Apelin_signaling_pathway_hsa04371 49 137 1.962e-08 6.801e-08
16 Phospholipase_D_signaling_pathway_hsa04072 51 146 2.502e-08 8.131e-08
17 mTOR_signaling_pathway_hsa04150 51 151 8.702e-08 2.662e-07
18 Calcium_signaling_pathway_hsa04020 56 182 7.055e-07 2.038e-06
19 Endocytosis_hsa04144 69 244 1.295e-06 3.545e-06
20 AMPK_signaling_pathway_hsa04152 41 121 1.405e-06 3.652e-06
21 ECM_receptor_interaction_hsa04512 31 82 1.959e-06 4.85e-06
22 HIF_1_signaling_pathway_hsa04066 35 100 3.519e-06 8.109e-06
23 Gap_junction_hsa04540 32 88 3.587e-06 8.109e-06
24 Sphingolipid_signaling_pathway_hsa04071 39 118 4.996e-06 1.083e-05
25 ErbB_signaling_pathway_hsa04012 30 85 1.415e-05 2.944e-05
26 Phosphatidylinositol_signaling_system_hsa04070 33 99 2.126e-05 4.251e-05
27 Jak_STAT_signaling_pathway_hsa04630 47 162 2.944e-05 5.669e-05
28 Tight_junction_hsa04530 47 170 0.0001086 0.0002017
29 Autophagy_animal_hsa04140 37 128 0.0002141 0.0003839
30 Cellular_senescence_hsa04218 43 160 0.0004056 0.000703
31 Oocyte_meiosis_hsa04114 35 124 0.0005104 0.0008375
32 Cytokine_cytokine_receptor_interaction_hsa04060 65 270 0.0005154 0.0008375
33 Cell_adhesion_molecules_.CAMs._hsa04514 39 145 0.000722 0.001138
34 Mitophagy_animal_hsa04137 20 65 0.002552 0.003902
35 Hedgehog_signaling_pathway_hsa04340 15 47 0.005782 0.00859
36 p53_signaling_pathway_hsa04115 19 68 0.0101 0.01459
37 Phagosome_hsa04145 36 152 0.01067 0.015
38 Hippo_signaling_pathway_multiple_species_hsa04392 10 29 0.01271 0.01739
39 TNF_signaling_pathway_hsa04668 25 108 0.03811 0.05082
40 VEGF_signaling_pathway_hsa04370 15 59 0.04626 0.06014
41 Necroptosis_hsa04217 35 164 0.04996 0.06289
42 ABC_transporters_hsa02010 12 45 0.05079 0.06289
43 Ferroptosis_hsa04216 10 40 0.1018 0.1232
44 Apoptosis_hsa04210 26 138 0.2308 0.2728
45 Cell_cycle_hsa04110 23 124 0.2734 0.3159
46 Peroxisome_hsa04146 15 83 0.3667 0.4138
47 Notch_signaling_pathway_hsa04330 9 48 0.374 0.4138
48 Neuroactive_ligand_receptor_interaction_hsa04080 45 278 0.5306 0.5748
49 NF_kappa_B_signaling_pathway_hsa04064 15 95 0.588 0.624
50 Autophagy_other_hsa04136 5 32 0.61 0.6344
51 Lysosome_hsa04142 19 123 0.6293 0.6385
52 Apoptosis_multiple_species_hsa04215 5 33 0.6385 0.6385

Quest ID: 4f182076feaf16150ff3e9bbb30dafc1