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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-200a-3p ABCA1 6.34 0 0.72 0.28064 mirMAP -0.22 0 NA
2 hsa-miR-429 ABCA1 6.4 0 0.72 0.28064 miRNATAP -0.24 0 NA
3 hsa-miR-429 ABCA9 6.4 0 -5.64 0 miRanda -0.3 0.00017 NA
4 hsa-miR-429 ABCB1 6.4 0 -4.36 0 miRanda -0.32 0 NA
5 hsa-miR-429 ABCB4 6.4 0 -2.11 0.0102 miRanda -0.2 0.00068 NA
6 hsa-miR-429 ABCC9 6.4 0 -5.85 0 miRanda; miRNATAP -0.39 0 NA
7 hsa-miR-429 ABCD2 6.4 0 -2.82 0.00416 miRanda -0.44 0 NA
8 hsa-miR-429 ABCG2 6.4 0 -5.58 0 miRanda -0.29 1.0E-5 NA
9 hsa-miR-429 ABCG4 6.4 0 -0.87 0.36278 miRanda -0.17 0.01509 NA
10 hsa-miR-200a-3p ABL2 6.34 0 -0.11 0.76409 MirTarget; miRNATAP -0.14 0 NA
11 hsa-miR-429 ABL2 6.4 0 -0.11 0.76409 MirTarget -0.13 0 NA
12 hsa-miR-429 ACHE 6.4 0 -1.22 0.32994 miRanda; miRNATAP -0.3 0.00089 NA
13 hsa-miR-429 ACOX2 6.4 0 -5.25 1.0E-5 miRanda; miRNATAP -0.22 0.00934 NA
14 hsa-miR-429 ACSL4 6.4 0 -0.89 0.13062 miRanda; miRNATAP -0.15 0.00067 NA
15 hsa-miR-429 ACTC1 6.4 0 -6.26 0 MirTarget; miRanda; miRNATAP -0.4 8.0E-5 NA
16 hsa-miR-429 ACTN1 6.4 0 -1.38 0.00663 miRanda -0.25 0 NA
17 hsa-miR-429 ACVRL1 6.4 0 -3.4 0 miRNATAP -0.27 0 NA
18 hsa-miR-429 ADAM12 6.4 0 2.46 0.0149 miRanda; miRNATAP -0.2 0.00793 NA
19 hsa-miR-429 ADAM19 6.4 0 0.44 0.52629 miRanda; miRNATAP -0.25 0 NA
20 hsa-miR-429 ADAMDEC1 6.4 0 4.7 0.00066 miRanda -0.35 0.00053 NA
21 hsa-miR-429 ADAMTS1 6.4 0 -4.72 0 miRanda -0.25 0.00031 NA
22 hsa-miR-429 ADAMTS10 6.4 0 -2.94 0.00037 miRNATAP -0.31 0 NA
23 hsa-miR-429 ADAMTS16 6.4 0 -2.85 0.04328 miRanda; miRNATAP -0.3 0.00411 NA
24 hsa-miR-429 ADAMTS2 6.4 0 -2.49 0.0191 miRNATAP -0.35 1.0E-5 NA
25 hsa-miR-429 ADAMTS3 6.4 0 -3.48 0.00158 PITA; miRanda; miRNATAP -0.42 0 NA
26 hsa-miR-429 ADAMTS4 6.4 0 -1.77 0.04016 miRanda -0.25 6.0E-5 NA
27 hsa-miR-429 ADAMTS6 6.4 0 -1.61 0.05287 miRNATAP -0.26 2.0E-5 NA
28 hsa-miR-429 ADAMTS9 6.4 0 -3.73 2.0E-5 PITA; miRanda -0.21 0.00122 NA
29 hsa-miR-429 ADAP2 6.4 0 0.46 0.46405 miRanda -0.26 0 NA
30 hsa-miR-200a-3p ADARB1 6.34 0 -2.48 1.0E-5 MirTarget -0.23 0 NA
31 hsa-miR-429 ADCY1 6.4 0 -1.34 0.20446 miRNATAP -0.17 0.02374 NA
32 hsa-miR-429 ADCY7 6.4 0 1.57 0.01053 miRanda -0.22 0 NA
33 hsa-miR-429 ADCY9 6.4 0 -0.65 0.18271 miRanda; miRNATAP -0.14 7.0E-5 NA
34 hsa-miR-429 ADCYAP1 6.4 0 -5.14 0.00012 miRanda -0.32 0.00097 NA
35 hsa-miR-429 ADH1B 6.4 0 -10.26 0 miRanda -0.32 0.00935 NA
36 hsa-miR-429 ADORA3 6.4 0 0.75 0.3525 miRNATAP -0.26 1.0E-5 NA
37 hsa-miR-429 AFF3 6.4 0 -4.69 0 MirTarget; PITA; miRanda; miRNATAP -0.29 3.0E-5 NA
38 hsa-miR-429 AGAP2 6.4 0 0.96 0.17024 miRNATAP -0.22 2.0E-5 NA
39 hsa-miR-200a-3p AGPAT4 6.34 0 -1.78 0.03177 mirMAP -0.17 0.00309 NA
40 hsa-miR-429 AGPAT4 6.4 0 -1.78 0.03177 miRNATAP -0.19 0.00216 NA
41 hsa-miR-429 AHNAK 6.4 0 -1.19 0.03091 PITA; miRanda; miRNATAP -0.18 1.0E-5 NA
42 hsa-miR-429 AKAP2 6.4 0 -3.13 0.04037 PITA; miRanda; miRNATAP -0.44 7.0E-5 NA
43 hsa-miR-429 AKNA 6.4 0 -1.69 0.00049 miRanda -0.15 1.0E-5 NA
44 hsa-miR-429 ALDH1A3 6.4 0 -0.41 0.74519 PITA; miRanda -0.26 0.00487 NA
45 hsa-miR-429 AMOTL2 6.4 0 -0.94 0.10811 MirTarget; PITA; miRanda; miRNATAP -0.22 0 NA
46 hsa-miR-429 AMPD3 6.4 0 1.34 0.01947 miRNATAP -0.12 0.00552 NA
47 hsa-miR-200a-3p AMZ1 6.34 0 -1.49 0.10286 mirMAP -0.28 1.0E-5 NA
48 hsa-miR-429 ANGPT1 6.4 0 -3.47 0.00041 miRanda -0.28 0.00011 NA
49 hsa-miR-429 ANGPT2 6.4 0 -1.02 0.17676 miRanda -0.16 0.00407 NA
50 hsa-miR-200a-3p ANGPTL1 6.34 0 -8.04 0 MirTarget -0.47 0 NA
51 hsa-miR-200a-3p ANK2 6.34 0 -5.41 0 miRNATAP -0.34 1.0E-5 NA
52 hsa-miR-429 ANK2 6.4 0 -5.41 0 miRanda; miRNATAP -0.32 9.0E-5 NA
53 hsa-miR-429 ANKH 6.4 0 -0.63 0.36736 PITA; miRanda; miRNATAP -0.24 0 NA
54 hsa-miR-200a-3p ANO6 6.34 0 -1.42 0.00017 MirTarget -0.16 0 NA
55 hsa-miR-429 ANO6 6.4 0 -1.42 0.00017 miRanda -0.17 0 NA
56 hsa-miR-429 ANTXR2 6.4 0 -4.25 0 miRNATAP -0.35 0 NA
57 hsa-miR-429 AP1M1 6.4 0 -0.48 0.0796 miRanda -0.14 0 NA
58 hsa-miR-429 AP1S2 6.4 0 -2.97 0 MirTarget; PITA; miRanda; miRNATAP -0.18 0 NA
59 hsa-miR-429 AP3S1 6.4 0 -0.38 0.28369 miRanda -0.1 7.0E-5 NA
60 hsa-miR-429 APBA1 6.4 0 -1.98 0.00925 miRNATAP -0.19 0.00084 NA
61 hsa-miR-429 APBB1 6.4 0 -4.51 0 miRNATAP -0.18 0.00447 NA
62 hsa-miR-200a-3p APBB2 6.34 0 -1.53 0.00158 MirTarget; miRNATAP -0.13 0.00019 NA
63 hsa-miR-429 APCDD1L 6.4 0 -1.42 0.37188 miRNATAP -0.57 0 NA
64 hsa-miR-429 APLF 6.4 0 -0.65 0.29807 miRanda -0.2 2.0E-5 NA
65 hsa-miR-200a-3p AR 6.34 0 -4.57 0.00169 mirMAP -0.23 0.02448 24391862 We identified miR-200 b as a downstream target of androgen receptor and linked its expression to decreased tumorigenicity and metastatic capacity of the prostate cancer cells
66 hsa-miR-429 AR 6.4 0 -4.57 0.00169 miRNATAP -0.22 0.03735 NA
67 hsa-miR-429 ARHGAP10 6.4 0 -1.22 0.04762 miRanda -0.22 0 NA
68 hsa-miR-429 ARHGAP15 6.4 0 -0.7 0.44662 miRanda -0.4 0 NA
69 hsa-miR-429 ARHGAP20 6.4 0 -3.56 0.00051 MirTarget; miRanda; miRNATAP -0.44 0 NA
70 hsa-miR-429 ARHGAP21 6.4 0 -0.14 0.76187 miRanda; miRNATAP -0.12 0.00029 NA
71 hsa-miR-429 ARHGAP25 6.4 0 -1.06 0.09204 miRNATAP -0.34 0 NA
72 hsa-miR-429 ARHGAP28 6.4 0 -2.52 0.04263 MirTarget -0.19 0.03802 NA
73 hsa-miR-429 ARHGAP6 6.4 0 -5.45 0 MirTarget; PITA; miRanda -0.28 4.0E-5 NA
74 hsa-miR-429 ARHGEF10 6.4 0 -1.41 0.0117 miRanda -0.16 7.0E-5 NA
75 hsa-miR-429 ARHGEF17 6.4 0 -2.19 1.0E-5 PITA; miRanda; miRNATAP -0.11 0.00274 NA
76 hsa-miR-429 ARHGEF4 6.4 0 1.39 0.1842 miRNATAP -0.25 0.00111 NA
77 hsa-miR-429 ARHGEF6 6.4 0 -2.31 0.00034 miRanda; mirMAP -0.33 0 NA
78 hsa-miR-200a-3p ARID5B 6.34 0 -2.21 0 miRNATAP -0.14 0 NA
79 hsa-miR-429 ARID5B 6.4 0 -2.21 0 miRanda; miRNATAP -0.15 0 NA
80 hsa-miR-200a-3p ARL10 6.34 0 -0.75 0.35282 mirMAP -0.27 0 NA
81 hsa-miR-429 ARL10 6.4 0 -0.75 0.35282 mirMAP -0.26 1.0E-5 NA
82 hsa-miR-429 ARL15 6.4 0 -0.85 0.14947 MirTarget; PITA; miRanda -0.14 0.001 NA
83 hsa-miR-429 ARL2BP 6.4 0 -0.97 0.00154 miRanda; miRNATAP -0.12 0 NA
84 hsa-miR-429 ARMCX1 6.4 0 -4.07 0 miRanda -0.3 0 NA
85 hsa-miR-429 ARPC2 6.4 0 0.48 0.19729 miRanda -0.1 0.00014 NA
86 hsa-miR-429 ASAP1 6.4 0 -0.15 0.71428 MirTarget; miRanda; miRNATAP -0.12 0.0001 NA
87 hsa-miR-429 ASPN 6.4 0 -5.37 0 miRanda -0.37 0 NA
88 hsa-miR-429 ATP11C 6.4 0 -0.87 0.09047 MirTarget; PITA; miRanda; miRNATAP -0.13 0.00066 NA
89 hsa-miR-429 ATP1A2 6.4 0 -6.92 0 miRNATAP -0.21 0.03137 NA
90 hsa-miR-429 ATP1B2 6.4 0 -5.25 0 miRNATAP -0.24 0.00021 NA
91 hsa-miR-429 ATRNL1 6.4 0 -7.16 0 miRanda -0.47 3.0E-5 NA
92 hsa-miR-429 B4GALNT1 6.4 0 0.06 0.96861 miRNATAP -0.35 0.00118 NA
93 hsa-miR-200a-3p BACH2 6.34 0 -2.73 0.00174 mirMAP -0.22 0.00035 NA
94 hsa-miR-429 BACH2 6.4 0 -2.73 0.00174 PITA; mirMAP; miRNATAP -0.18 0.00633 NA
95 hsa-miR-429 BASP1 6.4 0 -1.12 0.32909 PITA; miRanda; miRNATAP -0.55 0 NA
96 hsa-miR-429 BCHE 6.4 0 -7.18 0 miRanda -0.33 0.00222 NA
97 hsa-miR-429 BCL11B 6.4 0 2.87 0.00737 PITA; miRanda; miRNATAP -0.18 0.02231 NA
98 hsa-miR-429 BCL2 6.4 0 -3.06 1.0E-5 miRNAWalker2 validate; miRTarBase; PITA; mirMAP -0.16 0.00181 23999873; 26513239; 26511969 MiR 429 up regulation induces apoptosis and suppresses invasion by targeting Bcl 2 and SP 1 in esophageal carcinoma; Subsequent Western blotting and luciferase reporter assays showed that miR-429 can bind to putative binding sites within the Bcl-2 and SP1 mRNA 3' untranslated regions UTRs to reduce their expression; Up-regulation of miR-429 inhibits invasion and promotes apoptosis in EC cells by targeting Bcl-2 and SP1; Our findings suggest that Bcl-2 and SP1 may serve as major targets of miR-429;MiR 429 Induces Gastric Carcinoma Cell Apoptosis Through Bcl 2; Here we studied the levels of miR-429 and anti-apoptotic protein Bcl-2 in GC specimens; We performed bioinformatics analyses and used luciferase-reporter assay to analyze the relationship between miR-429 and Bcl-2 in GC cells; MiR-429 levels were significantly decreased and Bcl-2 levels were significantly increased in GC specimens compared to the paired adjacent non-tumor gastric tissue; Moreover the levels of miR-429 and Bcl-2 inversely correlated in GC specimens; Bioinformatics analyses showed that miR-429 targeted the 3'-UTR of Bcl-2 mRNA to inhibit its translation which was confirmed by luciferase-reporter assay;MiR 429 induces apoptosis of glioblastoma cell through Bcl 2; Here we analyzed the levels of miR-429 and anti-apoptotic protein Bcl-2 in GBM specimens; We combined bioinformatics analyses and luciferase reporter assay to determine the relationship between miR-429 and Bcl-2 in GBM cells; We found that miR-429 levels were significantly decreased and Bcl-2 levels were significantly increased in GBM specimens compared to the paired adjacent non-tumor brain tissue; Moreover the levels of miR-429 and Bcl-2 inversely correlated; MiR-429 targeted the 3'-UTR of Bcl-2 mRNA to inhibit its translation
99 hsa-miR-429 BCO2 6.4 0 -1.13 0.16359 miRanda -0.15 0.01163 NA
100 hsa-miR-429 BHLHE22 6.4 0 -0.71 0.48941 miRanda -0.33 1.0E-5 NA
101 hsa-miR-200a-3p BICD2 6.34 0 0.86 0.21413 MirTarget; miRNATAP -0.24 0 NA
102 hsa-miR-429 BICD2 6.4 0 0.86 0.21413 miRanda; miRNATAP -0.22 1.0E-5 NA
103 hsa-miR-429 BMP1 6.4 0 0.58 0.32408 miRNATAP -0.23 0 NA
104 hsa-miR-429 BMP2 6.4 0 0.6 0.59614 miRNATAP -0.32 0.00011 NA
105 hsa-miR-429 BMPER 6.4 0 -5.04 0.00019 PITA; miRanda -0.68 0 NA
106 hsa-miR-429 BNC2 6.4 0 -6.04 0 MirTarget; PITA; miRNATAP -0.44 0 NA
107 hsa-miR-429 BTBD11 6.4 0 3.32 0.00871 PITA; miRanda -0.21 0.02281 NA
108 hsa-miR-429 BTG1 6.4 0 -0.9 0.02841 miRNATAP -0.12 4.0E-5 NA
109 hsa-miR-429 BTLA 6.4 0 1.19 0.19794 miRNATAP -0.25 0.0002 NA
110 hsa-miR-429 C11orf87 6.4 0 -3.96 0.00131 miRNATAP -0.23 0.00978 NA
111 hsa-miR-429 C17orf51 6.4 0 -1.61 0.06048 mirMAP -0.19 0.00304 NA
112 hsa-miR-429 C19orf66 6.4 0 -0.21 0.63274 miRNATAP -0.15 0 NA
113 hsa-miR-200a-3p C1orf21 6.34 0 -1.27 0.0681 miRNATAP -0.19 5.0E-5 NA
114 hsa-miR-429 C1orf21 6.4 0 -1.27 0.0681 miRNATAP -0.24 0 NA
115 hsa-miR-200a-3p C20orf194 6.34 0 -1.86 0.0005 mirMAP -0.11 0.00408 NA
116 hsa-miR-429 C20orf194 6.4 0 -1.86 0.0005 miRNATAP -0.1 0.00866 NA
117 hsa-miR-429 C3orf18 6.4 0 -3.15 0 miRNATAP -0.17 0.00022 NA
118 hsa-miR-429 CACNA1C 6.4 0 -5.48 0 MirTarget; PITA; miRanda; miRNATAP -0.33 0 NA
119 hsa-miR-429 CACNA2D4 6.4 0 -0.44 0.39759 miRanda -0.18 0 NA
120 hsa-miR-429 CACNB2 6.4 0 -5.64 0 PITA; miRanda; miRNATAP -0.29 0 NA
121 hsa-miR-429 CALD1 6.4 0 -3.83 0 miRanda -0.44 0 NA
122 hsa-miR-429 CALU 6.4 0 -0.85 0.0346 MirTarget; PITA; miRanda -0.11 0.0001 NA
123 hsa-miR-429 CAMK2A 6.4 0 -4.61 0.0001 miRNATAP -0.6 0 NA
124 hsa-miR-200a-3p CAMK4 6.34 0 0.83 0.3952 mirMAP -0.27 7.0E-5 NA
125 hsa-miR-429 CAP2 6.4 0 -3.1 0.00035 miRanda -0.23 0.00023 NA
126 hsa-miR-429 CASP1 6.4 0 0.88 0.27422 miRanda -0.31 0 NA
127 hsa-miR-429 CASP10 6.4 0 0.7 0.33671 mirMAP; miRNATAP -0.13 0.01667 NA
128 hsa-miR-429 CASQ2 6.4 0 -7.69 0 miRanda; miRNATAP -0.28 0.00184 NA
129 hsa-miR-429 CAV2 6.4 0 -1.14 0.15869 miRNATAP -0.39 0 NA
130 hsa-miR-429 CBFA2T3 6.4 0 -1.36 0.14666 miRNATAP -0.19 0.00493 NA
131 hsa-miR-429 CCDC102B 6.4 0 -1.63 0.00581 miRanda -0.15 0.00037 NA
132 hsa-miR-429 CCDC3 6.4 0 -2.89 0.00047 miRanda -0.13 0.03889 NA
133 hsa-miR-429 CCDC69 6.4 0 -2.7 4.0E-5 miRNATAP -0.29 0 NA
134 hsa-miR-200a-3p CCDC80 6.34 0 -4.58 0 MirTarget -0.39 0 NA
135 hsa-miR-429 CCDC85A 6.4 0 -5.18 0 miRanda; miRNATAP -0.29 0.00012 NA
136 hsa-miR-429 CCDC88A 6.4 0 -0.17 0.77016 miRNATAP -0.17 8.0E-5 NA
137 hsa-miR-429 CCL11 6.4 0 -1.53 0.31995 miRanda -0.23 0.04019 NA
138 hsa-miR-429 CCL8 6.4 0 1.06 0.40217 miRanda -0.3 0.00094 NA
139 hsa-miR-200a-3p CCND2 6.34 0 -2.81 0.0014 MirTarget -0.41 0 NA
140 hsa-miR-429 CCND2 6.4 0 -2.81 0.0014 miRNATAP -0.46 0 NA
141 hsa-miR-429 CCND3 6.4 0 -0.54 0.12437 miRNATAP -0.11 1.0E-5 NA
142 hsa-miR-429 CCNJL 6.4 0 1.44 0.22112 miRanda; miRNATAP -0.29 0.00082 NA
143 hsa-miR-429 CCR1 6.4 0 0.42 0.57921 miRanda; miRNATAP -0.29 0 NA
144 hsa-miR-429 CCR2 6.4 0 -0.49 0.62976 miRanda -0.44 0 NA
145 hsa-miR-429 CD109 6.4 0 -0.13 0.90668 miRanda -0.49 0 NA
146 hsa-miR-429 CD160 6.4 0 -0.98 0.17699 miRanda -0.11 0.0421 NA
147 hsa-miR-429 CD163 6.4 0 -0.32 0.74836 miRNATAP -0.42 0 NA
148 hsa-miR-429 CD1D 6.4 0 -1.49 0.07848 miRanda -0.31 0 NA
149 hsa-miR-200a-3p CD274 6.34 0 2.22 0.05161 MirTarget -0.35 1.0E-5 NA
150 hsa-miR-429 CD274 6.4 0 2.22 0.05161 miRanda -0.41 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 BIOLOGICAL ADHESION 178 1032 2.269e-41 1.056e-37
2 VASCULATURE DEVELOPMENT 104 469 1.47e-33 3.419e-30
3 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 221 1672 5.479e-33 6.713e-30
4 BLOOD VESSEL MORPHOGENESIS 90 364 5.771e-33 6.713e-30
5 REGULATION OF CELLULAR COMPONENT MOVEMENT 136 771 1.7e-32 1.582e-29
6 CARDIOVASCULAR SYSTEM DEVELOPMENT 131 788 1.131e-28 7.517e-26
7 CIRCULATORY SYSTEM DEVELOPMENT 131 788 1.131e-28 7.517e-26
8 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 173 1275 6.891e-27 4.008e-24
9 CELL CELL ADHESION 108 608 4.018e-26 2.077e-23
10 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 181 1395 8.321e-26 3.872e-23
11 ANGIOGENESIS 71 293 1.251e-25 5.293e-23
12 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 218 1848 1.547e-25 5.536e-23
13 REGULATION OF CELL PROLIFERATION 189 1496 1.497e-25 5.536e-23
14 LOCOMOTION 153 1114 2.718e-24 9.034e-22
15 REGULATION OF CELL DIFFERENTIATION 185 1492 4.959e-24 1.538e-21
16 EXTRACELLULAR STRUCTURE ORGANIZATION 70 304 6.972e-24 2.028e-21
17 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 143 1021 1.539e-23 3.979e-21
18 TISSUE DEVELOPMENT 186 1518 1.478e-23 3.979e-21
19 IMMUNE SYSTEM PROCESS 222 1984 5.818e-23 1.425e-20
20 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 151 1142 2.658e-22 6.185e-20
21 CELL DEVELOPMENT 175 1426 3.279e-22 7.265e-20
22 REGULATION OF CELL ADHESION 103 629 3.927e-22 8.305e-20
23 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 133 957 1.33e-21 2.691e-19
24 CELL MOTILITY 120 835 9.671e-21 1.8e-18
25 LOCALIZATION OF CELL 120 835 9.671e-21 1.8e-18
26 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 114 799 1.736e-19 3.107e-17
27 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 162 1360 2.958e-19 5.005e-17
28 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 130 983 3.012e-19 5.005e-17
29 POSITIVE REGULATION OF RESPONSE TO STIMULUS 205 1929 1.603e-18 2.572e-16
30 SINGLE ORGANISM CELL ADHESION 79 459 1.697e-18 2.631e-16
31 NEUROGENESIS 163 1402 2.434e-18 3.654e-16
32 NEGATIVE REGULATION OF CELL COMMUNICATION 145 1192 4.564e-18 6.637e-16
33 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 182 1656 6.788e-18 9.571e-16
34 RESPONSE TO OXYGEN CONTAINING COMPOUND 159 1381 1.703e-17 2.331e-15
35 POSITIVE REGULATION OF LOCOMOTION 73 420 2.037e-17 2.708e-15
36 CELL ACTIVATION 87 568 5.663e-17 7.319e-15
37 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 107 801 2.847e-16 3.58e-14
38 RESPONSE TO WOUNDING 85 563 3.167e-16 3.878e-14
39 POSITIVE REGULATION OF CELL PROLIFERATION 108 814 3.307e-16 3.946e-14
40 REGULATION OF EPITHELIAL CELL PROLIFERATION 56 285 4.905e-16 5.706e-14
41 RESPONSE TO EXTERNAL STIMULUS 189 1821 5.322e-16 6.04e-14
42 RESPONSE TO ENDOGENOUS STIMULUS 160 1450 6.682e-16 7.403e-14
43 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 79 513 1.205e-15 1.304e-13
44 ORGAN MORPHOGENESIS 109 841 1.248e-15 1.32e-13
45 NEGATIVE REGULATION OF CELL PROLIFERATION 91 643 1.64e-15 1.695e-13
46 REGULATION OF VASCULATURE DEVELOPMENT 49 233 2.08e-15 2.104e-13
47 REGULATION OF CELL DEVELOPMENT 108 836 2.136e-15 2.115e-13
48 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 124 1036 5.317e-15 5.049e-13
49 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 124 1036 5.317e-15 5.049e-13
50 INTRACELLULAR SIGNAL TRANSDUCTION 166 1572 9.747e-15 9.07e-13
51 REGULATION OF PHOSPHORUS METABOLIC PROCESS 169 1618 1.438e-14 1.312e-12
52 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 93 689 1.521e-14 1.361e-12
53 NEGATIVE REGULATION OF LOCOMOTION 51 263 1.76e-14 1.528e-12
54 NEURON DIFFERENTIATION 109 874 1.773e-14 1.528e-12
55 REGULATION OF IMMUNE SYSTEM PROCESS 152 1403 1.887e-14 1.597e-12
56 POSITIVE REGULATION OF CELL DIFFERENTIATION 104 823 3.152e-14 2.619e-12
57 NEPHRON DEVELOPMENT 32 115 4.492e-14 3.667e-12
58 RESPONSE TO LIPID 109 888 5.172e-14 4.149e-12
59 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 119 1008 5.305e-14 4.184e-12
60 POSITIVE REGULATION OF CELL ADHESION 62 376 6.791e-14 5.266e-12
61 REGULATION OF NEURON DIFFERENTIATION 79 554 8.662e-14 6.607e-12
62 POSITIVE REGULATION OF GENE EXPRESSION 175 1733 9.847e-14 7.39e-12
63 CELLULAR COMPONENT MORPHOGENESIS 109 900 1.263e-13 9.328e-12
64 POSITIVE REGULATION OF CELL COMMUNICATION 159 1532 1.701e-13 1.237e-11
65 REGULATION OF EPITHELIAL CELL MIGRATION 38 166 1.795e-13 1.285e-11
66 CELLULAR RESPONSE TO LIPID 69 457 2.165e-13 1.526e-11
67 REGULATION OF CELL DEATH 154 1472 2.273e-13 1.579e-11
68 TISSUE MORPHOGENESIS 76 533 2.62e-13 1.793e-11
69 WOUND HEALING 70 470 2.84e-13 1.915e-11
70 EMBRYO DEVELOPMENT 107 894 4.631e-13 3.078e-11
71 SKELETAL SYSTEM DEVELOPMENT 68 455 5.313e-13 3.482e-11
72 EPITHELIUM DEVELOPMENT 111 945 5.639e-13 3.644e-11
73 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 33 133 6.342e-13 4.042e-11
74 GLOMERULUS DEVELOPMENT 20 49 8.629e-13 5.426e-11
75 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 94 750 9.525e-13 5.909e-11
76 RESPONSE TO HORMONE 106 893 1.014e-12 6.209e-11
77 TAXIS 68 464 1.353e-12 8.176e-11
78 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 153 1492 1.371e-12 8.177e-11
79 HEART DEVELOPMENT 68 466 1.659e-12 9.769e-11
80 NEGATIVE REGULATION OF CELL DIFFERENTIATION 81 609 1.802e-12 1.041e-10
81 REGULATION OF OSSIFICATION 38 178 1.813e-12 1.041e-10
82 ARTERY DEVELOPMENT 24 75 2.387e-12 1.354e-10
83 CELL CELL SIGNALING 94 767 3.49e-12 1.933e-10
84 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 175 1805 3.461e-12 1.933e-10
85 LEUKOCYTE DIFFERENTIATION 50 292 4.421e-12 2.42e-10
86 LEUKOCYTE CELL CELL ADHESION 46 255 4.946e-12 2.676e-10
87 LEUKOCYTE ACTIVATION 62 414 5.267e-12 2.797e-10
88 RESPONSE TO ORGANIC CYCLIC COMPOUND 106 917 5.289e-12 2.797e-10
89 POSITIVE REGULATION OF MOLECULAR FUNCTION 173 1791 6.436e-12 3.365e-10
90 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 102 876 8.92e-12 4.612e-10
91 CELL PROJECTION ORGANIZATION 104 902 9.945e-12 5.085e-10
92 UROGENITAL SYSTEM DEVELOPMENT 50 299 1.089e-11 5.507e-10
93 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 101 867 1.105e-11 5.529e-10
94 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 69 498 1.301e-11 6.439e-10
95 REGULATION OF CELL PROJECTION ORGANIZATION 74 558 1.954e-11 9.571e-10
96 IMMUNE SYSTEM DEVELOPMENT 76 582 2.206e-11 1.069e-09
97 MORPHOGENESIS OF A BRANCHING STRUCTURE 35 167 2.357e-11 1.131e-09
98 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 42 229 2.409e-11 1.142e-09
99 CIRCULATORY SYSTEM PROCESS 56 366 2.43e-11 1.142e-09
100 RESPONSE TO CYTOKINE 87 714 3.16e-11 1.47e-09
101 HOMOPHILIC CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 33 153 3.882e-11 1.788e-09
102 IMMUNE RESPONSE 118 1100 4.143e-11 1.89e-09
103 REGULATION OF PROTEIN MODIFICATION PROCESS 164 1710 4.423e-11 1.998e-09
104 MESENCHYME DEVELOPMENT 37 190 6.156e-11 2.754e-09
105 CELLULAR RESPONSE TO HORMONE STIMULUS 72 552 7.959e-11 3.461e-09
106 TUBE DEVELOPMENT 72 552 7.959e-11 3.461e-09
107 REGULATION OF CELL MORPHOGENESIS 72 552 7.959e-11 3.461e-09
108 MUSCLE STRUCTURE DEVELOPMENT 61 432 9.411e-11 4.055e-09
109 MORPHOGENESIS OF AN EPITHELIUM 58 400 9.557e-11 4.08e-09
110 LEUKOCYTE MIGRATION 44 259 1.115e-10 4.717e-09
111 NEURON PROJECTION DEVELOPMENT 71 545 1.143e-10 4.748e-09
112 CELL JUNCTION ORGANIZATION 36 185 1.139e-10 4.748e-09
113 CELL CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 38 204 1.336e-10 5.503e-09
114 NEURON DEVELOPMENT 83 687 1.404e-10 5.73e-09
115 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 119 1135 1.446e-10 5.851e-09
116 REGULATION OF OSTEOBLAST DIFFERENTIATION 27 112 1.608e-10 6.449e-09
117 ENDOTHELIUM DEVELOPMENT 24 90 1.762e-10 7.008e-09
118 ACTIN FILAMENT BASED PROCESS 62 450 1.835e-10 7.234e-09
119 TUBE MORPHOGENESIS 50 323 1.885e-10 7.372e-09
120 REGULATION OF SYSTEM PROCESS 67 507 2.091e-10 8.018e-09
121 REGULATION OF NEURON PROJECTION DEVELOPMENT 58 408 2.102e-10 8.018e-09
122 CELL JUNCTION ASSEMBLY 29 129 2.068e-10 8.018e-09
123 RESPONSE TO GROWTH FACTOR 64 475 2.388e-10 9.034e-09
124 REGULATION OF TRANSPORT 168 1804 2.468e-10 9.263e-09
125 STEM CELL DIFFERENTIATION 36 190 2.49e-10 9.269e-09
126 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 29 131 3.057e-10 1.129e-08
127 POSITIVE REGULATION OF MAPK CASCADE 63 470 4.092e-10 1.499e-08
128 HEART MORPHOGENESIS 38 212 4.264e-10 1.55e-08
129 EMBRYONIC MORPHOGENESIS 69 539 4.527e-10 1.633e-08
130 LYMPHOCYTE ACTIVATION 51 342 4.819e-10 1.725e-08
131 REGULATION OF CELL ACTIVATION 64 484 5.22e-10 1.854e-08
132 REGULATION OF METAL ION TRANSPORT 49 325 7.222e-10 2.546e-08
133 REGULATION OF HYDROLASE ACTIVITY 131 1327 8.446e-10 2.955e-08
134 REGULATION OF CELL CELL ADHESION 54 380 8.999e-10 3.125e-08
135 POSITIVE REGULATION OF CATALYTIC ACTIVITY 145 1518 9.268e-10 3.188e-08
136 NEURON PROJECTION MORPHOGENESIS 56 402 9.318e-10 3.188e-08
137 REGULATION OF CELL SUBSTRATE ADHESION 33 173 1.156e-09 3.925e-08
138 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 24 98 1.177e-09 3.97e-08
139 REGULATION OF ENDOTHELIAL CELL MIGRATION 26 114 1.272e-09 4.259e-08
140 REGULATION OF MAPK CASCADE 78 660 1.43e-09 4.754e-08
141 RESPONSE TO ABIOTIC STIMULUS 107 1024 1.602e-09 5.288e-08
142 NEGATIVE REGULATION OF CELL DEATH 95 872 1.703e-09 5.579e-08
143 CONNECTIVE TISSUE DEVELOPMENT 35 194 1.736e-09 5.647e-08
144 MUSCLE SYSTEM PROCESS 44 282 1.805e-09 5.832e-08
145 REGULATION OF ION TRANSPORT 72 592 1.824e-09 5.854e-08
146 ARTERY MORPHOGENESIS 17 51 1.862e-09 5.935e-08
147 MUCOPOLYSACCHARIDE METABOLIC PROCESS 25 108 1.897e-09 6.004e-08
148 POSITIVE REGULATION OF CELL DEATH 73 605 1.987e-09 6.248e-08
149 MULTICELLULAR ORGANISM METABOLIC PROCESS 23 93 2.117e-09 6.612e-08
150 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 105 1004 2.199e-09 6.82e-08
151 REGULATION OF BLOOD CIRCULATION 45 295 2.455e-09 7.566e-08
152 MULTICELLULAR ORGANISMAL MACROMOLECULE METABOLIC PROCESS 21 79 2.572e-09 7.872e-08
153 REGULATION OF HOMEOSTATIC PROCESS 59 447 2.675e-09 8.135e-08
154 REGULATION OF HOMOTYPIC CELL CELL ADHESION 46 307 2.931e-09 8.855e-08
155 POSITIVE REGULATION OF CELL DEVELOPMENT 61 472 3.267e-09 9.806e-08
156 REGULATION OF CHEMOTAXIS 33 180 3.308e-09 9.867e-08
157 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 24 103 3.461e-09 1.026e-07
158 LYMPHOCYTE DIFFERENTIATION 36 209 3.731e-09 1.099e-07
159 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 30 154 3.897e-09 1.14e-07
160 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 47 321 4.222e-09 1.228e-07
161 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 98 926 4.25e-09 1.228e-07
162 CELL SUBSTRATE ADHESION 31 164 4.603e-09 1.322e-07
163 CELLULAR RESPONSE TO CYTOKINE STIMULUS 72 606 4.982e-09 1.422e-07
164 GROWTH 55 410 5.206e-09 1.477e-07
165 REGULATION OF INTERLEUKIN 2 PRODUCTION 16 48 5.585e-09 1.575e-07
166 AMINOGLYCAN METABOLIC PROCESS 31 166 6.23e-09 1.746e-07
167 REGULATION OF IMMUNE RESPONSE 92 858 6.869e-09 1.914e-07
168 T CELL DIFFERENTIATION 26 123 7.086e-09 1.963e-07
169 CENTRAL NERVOUS SYSTEM DEVELOPMENT 93 872 7.39e-09 2.035e-07
170 REGULATION OF BODY FLUID LEVELS 63 506 7.808e-09 2.125e-07
171 AMINOGLYCAN BIOSYNTHETIC PROCESS 24 107 7.776e-09 2.125e-07
172 REGULATION OF KINASE ACTIVITY 85 776 9.94e-09 2.689e-07
173 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 160 1784 1.025e-08 2.756e-07
174 CYTOKINE MEDIATED SIGNALING PATHWAY 58 452 1.037e-08 2.773e-07
175 POSITIVE REGULATION OF HYDROLASE ACTIVITY 95 905 1.117e-08 2.97e-07
176 NEPHRON EPITHELIUM DEVELOPMENT 22 93 1.147e-08 3.034e-07
177 RENAL TUBULE DEVELOPMENT 20 78 1.207e-08 3.174e-07
178 CELL CHEMOTAXIS 30 162 1.334e-08 3.488e-07
179 REGULATION OF ACTIN FILAMENT BASED PROCESS 45 312 1.439e-08 3.74e-07
180 CELL MATRIX ADHESION 25 119 1.568e-08 4.053e-07
181 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 66 554 1.981e-08 5.092e-07
182 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 23 104 2.111e-08 5.397e-07
183 POSITIVE REGULATION OF CELL CELL ADHESION 38 243 2.151e-08 5.469e-07
184 NEGATIVE REGULATION OF CELL ADHESION 36 223 2.171e-08 5.49e-07
185 RESPONSE TO NITROGEN COMPOUND 90 859 3.028e-08 7.617e-07
186 REGULATION OF GROWTH 72 633 3.062e-08 7.659e-07
187 AORTA DEVELOPMENT 14 41 3.551e-08 8.788e-07
188 CELL SUBSTRATE JUNCTION ASSEMBLY 14 41 3.551e-08 8.788e-07
189 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 18 68 3.769e-08 9.278e-07
190 DEVELOPMENTAL GROWTH 46 333 3.823e-08 9.362e-07
191 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 64 541 4.245e-08 1.029e-06
192 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 64 541 4.245e-08 1.029e-06
193 POSITIVE REGULATION OF KINASE ACTIVITY 59 482 4.322e-08 1.042e-06
194 CELLULAR RESPONSE TO VASCULAR ENDOTHELIAL GROWTH FACTOR STIMULUS 12 30 4.383e-08 1.051e-06
195 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 49 368 4.52e-08 1.079e-06
196 MESENCHYMAL CELL DIFFERENTIATION 26 134 4.569e-08 1.085e-06
197 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 46 337 5.507e-08 1.294e-06
198 REGULATION OF ION HOMEOSTASIS 33 201 5.499e-08 1.294e-06
199 CELLULAR RESPONSE TO BIOTIC STIMULUS 29 163 5.819e-08 1.361e-06
200 POSITIVE REGULATION OF NEURON DIFFERENTIATION 43 306 6.449e-08 1.5e-06
201 POSITIVE REGULATION OF INTERLEUKIN 2 PRODUCTION 12 31 6.775e-08 1.568e-06
202 REGULATION OF RESPONSE TO STRESS 134 1468 6.864e-08 1.581e-06
203 REGULATION OF CYTOKINE PRODUCTION 65 563 8.341e-08 1.912e-06
204 ENDOTHELIAL CELL MIGRATION 16 57 8.748e-08 1.995e-06
205 NEGATIVE REGULATION OF PHOSPHORYLATION 53 422 9.122e-08 2.07e-06
206 RESPONSE TO OXYGEN LEVELS 43 311 1.03e-07 2.326e-06
207 COLLAGEN FIBRIL ORGANIZATION 13 38 1.069e-07 2.392e-06
208 ACTIVATION OF PROTEIN KINASE ACTIVITY 40 279 1.068e-07 2.392e-06
209 REGULATION OF RESPONSE TO WOUNDING 52 413 1.112e-07 2.475e-06
210 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 24 122 1.136e-07 2.518e-06
211 REGULATION OF ANATOMICAL STRUCTURE SIZE 57 472 1.165e-07 2.569e-06
212 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 54 437 1.183e-07 2.585e-06
213 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 54 437 1.183e-07 2.585e-06
214 REGULATION OF HEMOPOIESIS 43 314 1.356e-07 2.934e-06
215 SPROUTING ANGIOGENESIS 14 45 1.352e-07 2.934e-06
216 CELL CELL SIGNALING INVOLVED IN CARDIAC CONDUCTION 10 22 1.389e-07 2.992e-06
217 REGULATION OF CALCIUM ION TRANSPORT 33 209 1.425e-07 3.056e-06
218 HEAD DEVELOPMENT 76 709 1.495e-07 3.191e-06
219 PLATELET ACTIVATION 26 142 1.544e-07 3.281e-06
220 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 56 465 1.649e-07 3.489e-06
221 REGULATION OF ORGAN MORPHOGENESIS 36 242 1.818e-07 3.827e-06
222 KIDNEY EPITHELIUM DEVELOPMENT 24 125 1.834e-07 3.843e-06
223 CELL DEATH 98 1001 1.978e-07 4.127e-06
224 MUSCLE CONTRACTION 35 233 2.109e-07 4.381e-06
225 SENSORY ORGAN DEVELOPMENT 58 493 2.212e-07 4.574e-06
226 RESPONSE TO BIOTIC STIMULUS 89 886 2.426e-07 4.996e-06
227 CHEMICAL HOMEOSTASIS 88 874 2.568e-07 5.263e-06
228 MEMBRANE DEPOLARIZATION DURING CARDIAC MUSCLE CELL ACTION POTENTIAL 8 14 2.707e-07 5.525e-06
229 HEMOSTASIS 42 311 2.783e-07 5.654e-06
230 CARTILAGE DEVELOPMENT 26 147 3.139e-07 6.35e-06
231 CELL PROLIFERATION 72 672 3.256e-07 6.558e-06
232 DEFENSE RESPONSE 114 1231 3.477e-07 6.949e-06
233 POSITIVE REGULATION OF CYTOKINE PRODUCTION 47 370 3.48e-07 6.949e-06
234 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 41 303 3.649e-07 7.256e-06
235 CARDIAC EPITHELIAL TO MESENCHYMAL TRANSITION 10 24 3.787e-07 7.498e-06
236 KIDNEY VASCULATURE DEVELOPMENT 9 19 3.862e-07 7.582e-06
237 RENAL SYSTEM VASCULATURE DEVELOPMENT 9 19 3.862e-07 7.582e-06
238 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 23 121 3.965e-07 7.752e-06
239 REGULATION OF CARTILAGE DEVELOPMENT 16 63 3.983e-07 7.755e-06
240 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 108 1152 4.002e-07 7.758e-06
241 INFLAMMATORY RESPONSE 54 454 4.08e-07 7.877e-06
242 RESPONSE TO ALCOHOL 46 362 4.582e-07 8.809e-06
243 CELLULAR RESPONSE TO NITROGEN COMPOUND 58 505 4.952e-07 9.482e-06
244 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 38 274 5.2e-07 9.917e-06
245 REGULATION OF HEART CONTRACTION 33 221 5.351e-07 1.014e-05
246 ENDOTHELIAL CELL DIFFERENTIATION 17 72 5.38e-07 1.014e-05
247 MULTICELLULAR ORGANISMAL SIGNALING 23 123 5.378e-07 1.014e-05
248 GLAND MORPHOGENESIS 20 97 5.801e-07 1.088e-05
249 REGULATION OF MEMBRANE POTENTIAL 44 343 6.241e-07 1.166e-05
250 CELL COMMUNICATION INVOLVED IN CARDIAC CONDUCTION 12 37 6.432e-07 1.183e-05
251 CARDIAC MUSCLE CELL ACTION POTENTIAL 12 37 6.432e-07 1.183e-05
252 NEGATIVE REGULATION OF EPITHELIAL CELL DIFFERENTIATION 12 37 6.432e-07 1.183e-05
253 AXON EXTENSION 12 37 6.432e-07 1.183e-05
254 REGULATION OF TRANSMEMBRANE TRANSPORT 51 426 7.012e-07 1.284e-05
255 POSITIVE REGULATION OF CELL ACTIVATION 41 311 7.316e-07 1.335e-05
256 BRANCHING INVOLVED IN URETERIC BUD MORPHOGENESIS 13 44 7.404e-07 1.346e-05
257 REGULATION OF DEVELOPMENTAL GROWTH 39 289 7.493e-07 1.357e-05
258 CARDIAC CONDUCTION 18 82 8.004e-07 1.443e-05
259 CELL GROWTH 24 135 8.034e-07 1.443e-05
260 NEURON PROJECTION GUIDANCE 31 205 8.877e-07 1.589e-05
261 CELLULAR RESPONSE TO ACID CHEMICAL 28 175 9.399e-07 1.676e-05
262 PROTEOGLYCAN METABOLIC PROCESS 18 83 9.673e-07 1.711e-05
263 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 20 100 9.672e-07 1.711e-05
264 REGULATION OF LEUKOCYTE PROLIFERATION 31 206 9.881e-07 1.742e-05
265 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL 17 75 9.986e-07 1.753e-05
266 BEHAVIOR 58 516 1.003e-06 1.755e-05
267 PROTEIN PHOSPHORYLATION 91 944 1.072e-06 1.869e-05
268 REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 19 92 1.076e-06 1.869e-05
269 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 15 60 1.139e-06 1.97e-05
270 TISSUE MIGRATION 18 84 1.165e-06 2.008e-05
271 REGULATION OF CELL JUNCTION ASSEMBLY 16 68 1.215e-06 2.081e-05
272 NEGATIVE REGULATION OF TRANSPORT 53 458 1.219e-06 2.081e-05
273 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 31 208 1.221e-06 2.081e-05
274 POSITIVE REGULATION OF INTERLEUKIN 2 BIOSYNTHETIC PROCESS 7 12 1.312e-06 2.228e-05
275 POSITIVE REGULATION OF CHEMOTAXIS 22 120 1.337e-06 2.263e-05
276 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 10 27 1.388e-06 2.341e-05
277 MUSCLE TISSUE DEVELOPMENT 37 275 1.538e-06 2.584e-05
278 DIVALENT INORGANIC CATION HOMEOSTASIS 43 343 1.549e-06 2.592e-05
279 REGULATION OF LEUKOCYTE DIFFERENTIATION 33 232 1.628e-06 2.715e-05
280 LYMPHOCYTE COSTIMULATION 17 78 1.79e-06 2.975e-05
281 POSITIVE REGULATION OF IMMUNE RESPONSE 61 563 1.805e-06 2.988e-05
282 MUSCLE ORGAN DEVELOPMENT 37 277 1.833e-06 3.024e-05
283 HEART VALVE DEVELOPMENT 11 34 1.945e-06 3.198e-05
284 REGULATION OF KERATINOCYTE PROLIFERATION 10 28 2.048e-06 3.355e-05
285 REGULATION OF CELLULAR LOCALIZATION 114 1277 2.112e-06 3.441e-05
286 EMBRYONIC ORGAN DEVELOPMENT 48 406 2.115e-06 3.441e-05
287 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 45 372 2.369e-06 3.84e-05
288 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 21 115 2.471e-06 3.978e-05
289 CELLULAR RESPONSE TO ALCOHOL 21 115 2.471e-06 3.978e-05
290 MUSCLE CELL DIFFERENTIATION 33 237 2.623e-06 4.209e-05
291 CARDIAC CHAMBER DEVELOPMENT 24 144 2.649e-06 4.236e-05
292 EPITHELIAL CELL DIFFERENTIATION 55 495 2.715e-06 4.326e-05
293 REGULATION OF GTPASE ACTIVITY 69 673 2.778e-06 4.411e-05
294 CELL FATE COMMITMENT 32 227 2.834e-06 4.485e-05
295 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 21 116 2.855e-06 4.502e-05
296 REGULATION OF ERK1 AND ERK2 CASCADE 33 238 2.88e-06 4.527e-05
297 REGULATION OF SEQUESTERING OF CALCIUM ION 20 107 2.932e-06 4.594e-05
298 CARDIAC MUSCLE CELL CONTRACTION 10 29 2.964e-06 4.628e-05
299 SYNAPSE ORGANIZATION 24 145 3.003e-06 4.673e-05
300 RESPONSE TO STEROID HORMONE 55 497 3.068e-06 4.758e-05
301 LEUKOCYTE CHEMOTAXIS 21 117 3.292e-06 5.089e-05
302 CELLULAR RESPONSE TO KETONE 16 73 3.315e-06 5.108e-05
303 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 29 197 3.432e-06 5.27e-05
304 T CELL SELECTION 11 36 3.67e-06 5.617e-05
305 INTEGRIN MEDIATED SIGNALING PATHWAY 17 82 3.714e-06 5.666e-05
306 RESPONSE TO PEPTIDE 47 404 4.19e-06 6.371e-05
307 SENSORY PERCEPTION OF PAIN 16 75 4.82e-06 7.305e-05
308 REGULATION OF LEUKOCYTE MIGRATION 24 149 4.894e-06 7.394e-05
309 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 32 233 4.968e-06 7.481e-05
310 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 15 67 5.055e-06 7.587e-05
311 CELL PART MORPHOGENESIS 65 633 5.127e-06 7.626e-05
312 VASCULAR ENDOTHELIAL GROWTH FACTOR SIGNALING PATHWAY 7 14 5.13e-06 7.626e-05
313 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 36 278 5.163e-06 7.626e-05
314 POSITIVE REGULATION OF TYPE 2 IMMUNE RESPONSE 7 14 5.13e-06 7.626e-05
315 SKELETAL SYSTEM MORPHOGENESIS 29 201 5.147e-06 7.626e-05
316 POSITIVE REGULATION OF OSSIFICATION 17 84 5.248e-06 7.727e-05
317 RENAL SYSTEM PROCESS 19 102 5.433e-06 7.975e-05
318 SECOND MESSENGER MEDIATED SIGNALING 25 160 5.469e-06 8.002e-05
319 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 52 470 5.713e-06 8.332e-05
320 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 30 213 5.839e-06 8.464e-05
321 MULTI MULTICELLULAR ORGANISM PROCESS 30 213 5.839e-06 8.464e-05
322 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 14 60 6.215e-06 8.938e-05
323 CHONDROITIN SULFATE BIOSYNTHETIC PROCESS 9 25 6.224e-06 8.938e-05
324 HEART PROCESS 17 85 6.21e-06 8.938e-05
325 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 21 122 6.535e-06 9.356e-05
326 REGULATION OF LYMPHOCYTE DIFFERENTIATION 22 132 6.829e-06 9.746e-05
327 DEVELOPMENTAL CELL GROWTH 16 77 6.909e-06 9.83e-05
328 REGULATION OF STEM CELL DIFFERENTIATION 20 113 6.981e-06 9.903e-05
329 NEGATIVE REGULATION OF EPITHELIAL CELL MIGRATION 13 53 7.374e-06 0.000104
330 MESONEPHRIC TUBULE MORPHOGENESIS 13 53 7.374e-06 0.000104
331 POSITIVE REGULATION OF T CELL PROLIFERATION 18 95 7.438e-06 0.0001042
332 NEGATIVE REGULATION OF OSSIFICATION 15 69 7.431e-06 0.0001042
333 POSITIVE REGULATION OF TRANSPORT 87 936 7.902e-06 0.0001104
334 REGULATION OF MAP KINASE ACTIVITY 39 319 8.537e-06 0.0001189
335 TISSUE REMODELING 17 87 8.621e-06 0.0001197
336 MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL 11 39 8.721e-06 0.0001208
337 AMEBOIDAL TYPE CELL MIGRATION 24 154 8.758e-06 0.0001209
338 INTERFERON GAMMA MEDIATED SIGNALING PATHWAY 15 70 8.957e-06 0.0001233
339 RESPONSE TO BACTERIUM 56 528 8.988e-06 0.0001234
340 REGULATION OF TYPE 2 IMMUNE RESPONSE 9 26 9.03e-06 0.0001236
341 CELL MIGRATION INVOLVED IN SPROUTING ANGIOGENESIS 7 15 9.137e-06 0.0001243
342 OSSIFICATION 33 251 9.134e-06 0.0001243
343 CELLULAR RESPONSE TO PEPTIDE 35 274 9.409e-06 0.0001276
344 REGULATION OF SECRETION 69 699 1.01e-05 0.0001366
345 PATTERN SPECIFICATION PROCESS 47 418 1.043e-05 0.0001406
346 HOMEOSTATIC PROCESS 115 1337 1.075e-05 0.0001446
347 REGULATION OF WOUND HEALING 21 126 1.097e-05 0.0001467
348 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 24 156 1.096e-05 0.0001467
349 POSITIVE REGULATION OF LEUKOCYTE PROLIFERATION 22 136 1.118e-05 0.0001489
350 REGULATION OF T CELL DIFFERENTIATION 19 107 1.12e-05 0.0001489
351 REGULATION OF POSTSYNAPTIC MEMBRANE POTENTIAL 13 55 1.142e-05 0.0001513
352 REGULATION OF TRANSFERASE ACTIVITY 87 946 1.187e-05 0.0001569
353 RESPONSE TO MECHANICAL STIMULUS 29 210 1.221e-05 0.0001605
354 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 31 232 1.218e-05 0.0001605
355 CHONDROCYTE DEVELOPMENT 8 21 1.273e-05 0.0001669
356 MYELOID LEUKOCYTE MIGRATION 18 99 1.351e-05 0.0001761
357 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 18 99 1.351e-05 0.0001761
358 NEGATIVE REGULATION OF CELL ACTIVATION 24 158 1.366e-05 0.0001775
359 EMBRYONIC ORGAN MORPHOGENESIS 35 279 1.398e-05 0.0001811
360 EPITHELIAL TO MESENCHYMAL TRANSITION 13 56 1.408e-05 0.000182
361 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 22 138 1.419e-05 0.0001829
362 REGULATION OF BLOOD PRESSURE 25 169 1.456e-05 0.0001872
363 NEGATIVE REGULATION OF CELL DEVELOPMENT 37 303 1.479e-05 0.0001896
364 RETINA VASCULATURE DEVELOPMENT IN CAMERA TYPE EYE 7 16 1.543e-05 0.0001973
365 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 41 352 1.643e-05 0.0002095
366 RESPONSE TO VIRUS 32 247 1.679e-05 0.0002134
367 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 42 365 1.747e-05 0.0002216
368 REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION 28 203 1.753e-05 0.0002217
369 CARDIAC MUSCLE TISSUE DEVELOPMENT 22 140 1.791e-05 0.0002254
370 REGULATION OF SPROUTING ANGIOGENESIS 9 28 1.797e-05 0.0002254
371 REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 18 101 1.797e-05 0.0002254
372 REGULATION OF CELL GROWTH 44 391 1.938e-05 0.0002424
373 POSITIVE REGULATION OF ERK1 AND ERK2 CASCADE 25 172 1.981e-05 0.0002471
374 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 45 404 2.023e-05 0.0002517
375 METAL ION TRANSPORT 59 582 2.036e-05 0.0002526
376 NEGATIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 24 162 2.091e-05 0.0002581
377 POSITIVE REGULATION OF RESPONSE TO WOUNDING 24 162 2.091e-05 0.0002581
378 POSITIVE REGULATION OF CYTOKINE BIOSYNTHETIC PROCESS 13 58 2.111e-05 0.0002599
379 CELLULAR CHEMICAL HOMEOSTASIS 58 570 2.143e-05 0.0002631
380 ACTIN FILAMENT BASED MOVEMENT 17 93 2.165e-05 0.0002651
381 CELLULAR HOMEOSTASIS 66 676 2.224e-05 0.0002716
382 FOREBRAIN DEVELOPMENT 41 357 2.293e-05 0.0002793
383 REGULATION OF CALCIUM ION IMPORT 18 103 2.369e-05 0.0002878
384 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 14 67 2.399e-05 0.0002907
385 CHONDROITIN SULFATE PROTEOGLYCAN METABOLIC PROCESS 11 43 2.417e-05 0.0002921
386 REGULATION OF DEFENSE RESPONSE 72 759 2.488e-05 0.0002992
387 GLAND DEVELOPMENT 44 395 2.488e-05 0.0002992
388 ACTION POTENTIAL 17 94 2.502e-05 3e-04
389 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 28 207 2.522e-05 0.0003016
390 CARDIAC SEPTUM DEVELOPMENT 16 85 2.57e-05 0.0003058
391 VASCULOGENESIS 13 59 2.566e-05 0.0003058
392 REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 12 51 2.595e-05 0.0003081
393 NEGATIVE REGULATION OF MOLECULAR FUNCTION 95 1079 2.678e-05 0.0003171
394 CARDIAC CHAMBER MORPHOGENESIS 18 104 2.712e-05 0.0003203
395 RESPONSE TO INTERFERON GAMMA 22 144 2.808e-05 0.0003308
396 INTERACTION WITH HOST 21 134 2.873e-05 0.0003376
397 ION HOMEOSTASIS 58 576 2.899e-05 0.0003398
398 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 61 616 2.985e-05 0.000349
399 MODULATION OF SYNAPTIC TRANSMISSION 36 301 3.011e-05 0.0003511
400 CHONDROCYTE DIFFERENTIATION 13 60 3.103e-05 0.000361
401 ACTIVATION OF MAPKK ACTIVITY 12 52 3.198e-05 0.000371
402 EYE DEVELOPMENT 38 326 3.254e-05 0.0003766
403 CARDIOCYTE DIFFERENTIATION 17 96 3.319e-05 0.0003833
404 BONE DEVELOPMENT 23 156 3.334e-05 0.000384
405 CHONDROITIN SULFATE PROTEOGLYCAN BIOSYNTHETIC PROCESS 9 30 3.351e-05 0.000385
406 MOVEMENT IN ENVIRONMENT OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 16 87 3.469e-05 0.0003918
407 ENTRY INTO CELL OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 16 87 3.469e-05 0.0003918
408 VIRAL ENTRY INTO HOST CELL 16 87 3.469e-05 0.0003918
409 ENTRY INTO OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 16 87 3.469e-05 0.0003918
410 MOVEMENT IN HOST ENVIRONMENT 16 87 3.469e-05 0.0003918
411 ENTRY INTO HOST 16 87 3.469e-05 0.0003918
412 ENTRY INTO HOST CELL 16 87 3.469e-05 0.0003918
413 SYSTEM PROCESS 143 1785 3.482e-05 0.0003923
414 NEGATIVE REGULATION OF SECRETION 27 200 3.618e-05 0.0004067
415 MEMBRANE DEPOLARIZATION 13 61 3.737e-05 0.000419
416 REGULATION OF ALCOHOL BIOSYNTHETIC PROCESS 11 45 3.834e-05 0.0004289
417 REGULATION OF INTERLEUKIN 2 BIOSYNTHETIC PROCESS 7 18 3.874e-05 0.0004313
418 GANGLIOSIDE BIOSYNTHETIC PROCESS 7 18 3.874e-05 0.0004313
419 NEURON PROJECTION EXTENSION 12 53 3.918e-05 0.000434
420 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 12 53 3.918e-05 0.000434
421 BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 8 24 3.937e-05 0.0004342
422 EPITHELIAL CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 8 24 3.937e-05 0.0004342
423 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 26 191 4.341e-05 0.0004775
424 NEGATIVE REGULATION OF GROWTH 30 236 4.369e-05 0.0004795
425 FOREBRAIN CELL MIGRATION 13 62 4.48e-05 0.0004894
426 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION 9 31 4.48e-05 0.0004894
427 RESPONSE TO ACID CHEMICAL 37 319 4.573e-05 0.0004983
428 NEGATIVE REGULATION OF CELL GROWTH 24 170 4.667e-05 0.0005073
429 REGULATION OF CHONDROCYTE DIFFERENTIATION 11 46 4.778e-05 0.0005182
430 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 35 296 4.894e-05 0.0005295
431 REGULATION OF CELL SHAPE 21 139 5.013e-05 0.0005412
432 POSITIVE REGULATION OF GROWTH 30 238 5.121e-05 0.0005516
433 RESPONSE TO KETONE 25 182 5.196e-05 0.0005584
434 GLYCOSPHINGOLIPID BIOSYNTHETIC PROCESS 8 25 5.498e-05 0.0005894
435 REGULATION OF PHOSPHOLIPASE C ACTIVITY 10 39 5.535e-05 0.0005907
436 NEGATIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 10 39 5.535e-05 0.0005907
437 NEURON MIGRATION 18 110 5.866e-05 0.0006245
438 ENDOCARDIAL CUSHION DEVELOPMENT 9 32 5.915e-05 0.0006269
439 BLOOD VESSEL REMODELING 9 32 5.915e-05 0.0006269
440 REGIONALIZATION 36 311 6.006e-05 0.0006351
441 REGULATION OF CELLULAR COMPONENT BIOGENESIS 71 767 6.171e-05 0.0006511
442 REGULATION OF MUSCLE SYSTEM PROCESS 26 195 6.193e-05 0.0006519
443 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 25 184 6.234e-05 0.0006548
444 AGING 32 264 6.302e-05 0.0006604
445 REGULATION OF PHOSPHOLIPASE ACTIVITY 13 64 6.361e-05 0.0006651
446 KIDNEY MORPHOGENESIS 15 82 6.446e-05 0.0006725
447 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 18 111 6.628e-05 0.0006899
448 POSITIVE REGULATION OF HEMOPOIESIS 23 163 6.713e-05 0.0006941
449 CYTOSKELETON ORGANIZATION 76 838 6.713e-05 0.0006941
450 VASCULAR PROCESS IN CIRCULATORY SYSTEM 23 163 6.713e-05 0.0006941
451 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 26 197 7.362e-05 0.0007581
452 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 17 102 7.365e-05 0.0007581
453 EPITHELIAL CELL DEVELOPMENT 25 186 7.454e-05 0.0007617
454 POSITIVE REGULATION OF SPROUTING ANGIOGENESIS 6 14 7.465e-05 0.0007617
455 CELLULAR RESPONSE TO VITAMIN D 6 14 7.465e-05 0.0007617
456 POSITIVE REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION INVOLVED IN PHOSPHOLIPASE C ACTIVATING G PROTEIN COUPLED SIGNALING PATHWAY 6 14 7.465e-05 0.0007617
457 GANGLIOSIDE METABOLIC PROCESS 8 26 7.54e-05 0.0007643
458 NEGATIVE REGULATION OF CARTILAGE DEVELOPMENT 8 26 7.54e-05 0.0007643
459 REGULATION OF P38MAPK CASCADE 8 26 7.54e-05 0.0007643
460 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 14 74 7.655e-05 0.0007709
461 ACTIN MEDIATED CELL CONTRACTION 14 74 7.655e-05 0.0007709
462 CELL CELL JUNCTION ASSEMBLY 14 74 7.655e-05 0.0007709
463 REGULATION OF TRANSPORTER ACTIVITY 26 198 8.018e-05 0.0008058
464 POSITIVE REGULATION OF BLOOD CIRCULATION 16 93 8.044e-05 0.0008067
465 REGULATION OF ADAPTIVE IMMUNE RESPONSE 19 123 8.295e-05 0.0008301
466 CYCLIC NUCLEOTIDE METABOLIC PROCESS 12 57 8.383e-05 0.0008353
467 REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 12 57 8.383e-05 0.0008353
468 REGULATION OF MONOCYTE CHEMOTAXIS 7 20 8.519e-05 0.000847
469 REGULATION OF CYCLIC NUCLEOTIDE METABOLIC PROCESS 22 155 8.769e-05 0.00087
470 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 11 49 8.894e-05 0.0008805
471 NEURAL CREST CELL DIFFERENTIATION 14 75 8.917e-05 0.0008809
472 REGULATION OF NUCLEOTIDE METABOLIC PROCESS 27 211 9.218e-05 0.0009087
473 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 93 1087 9.393e-05 0.000924
474 NOTCH SIGNALING PATHWAY 18 114 9.467e-05 0.0009293
475 CALCIUM ION TRANSPORT 28 223 9.62e-05 0.0009423
476 RESPONSE TO FLUID SHEAR STRESS 9 34 9.961e-05 0.0009737
477 PROTEOGLYCAN BIOSYNTHETIC PROCESS 12 58 0.0001002 0.0009774
478 POSITIVE REGULATION OF CD4 POSITIVE ALPHA BETA T CELL ACTIVATION 8 27 0.0001017 0.0009861
479 REGULATION OF CATENIN IMPORT INTO NUCLEUS 8 27 0.0001017 0.0009861
480 HETEROTYPIC CELL CELL ADHESION 8 27 0.0001017 0.0009861
481 REGULATION OF CALCIUM MEDIATED SIGNALING 14 76 0.0001036 0.001002
482 POSITIVE REGULATION OF ION TRANSPORT 29 236 0.0001071 0.001034
483 REGULATION OF ADHERENS JUNCTION ORGANIZATION 11 50 0.0001081 0.001037
484 STAT CASCADE 11 50 0.0001081 0.001037
485 JAK STAT CASCADE 11 50 0.0001081 0.001037
486 REGULATION OF HEART RATE 15 86 0.0001134 0.001086
487 REGULATION OF T CELL PROLIFERATION 21 147 0.0001145 0.001092
488 IMMUNE EFFECTOR PROCESS 49 486 0.0001145 0.001092
489 APPENDAGE DEVELOPMENT 23 169 0.0001176 0.001117
490 LIMB DEVELOPMENT 23 169 0.0001176 0.001117
491 POSITIVE REGULATION OF MONOCYTE CHEMOTAXIS 6 15 0.0001183 0.001121
492 SINGLE ORGANISM BEHAVIOR 41 384 0.0001195 0.001131
493 REGULATION OF SODIUM ION TRANSPORT 14 77 0.0001199 0.001132
494 CARDIAC VENTRICLE DEVELOPMENT 17 106 0.0001205 0.001135
495 SIALYLATION 7 21 0.0001214 0.001141
496 REGULATION OF ALPHA BETA T CELL ACTIVATION 13 68 0.0001225 0.001142
497 ORGAN GROWTH 13 68 0.0001225 0.001142
498 NERVE DEVELOPMENT 13 68 0.0001225 0.001142
499 ADENYLATE CYCLASE INHIBITING G PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY 13 68 0.0001225 0.001142
500 REGULATION OF WNT SIGNALING PATHWAY 35 310 0.0001245 0.001159
501 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 31 262 0.0001275 0.001184
502 POSITIVE REGULATION OF ALPHA BETA T CELL ACTIVATION 11 51 0.0001307 0.001212
503 COGNITION 30 251 0.0001358 0.001254
504 DEVELOPMENTAL MATURATION 25 193 0.0001359 0.001254
505 TELENCEPHALON DEVELOPMENT 28 228 0.0001412 0.001301
506 ADAPTIVE IMMUNE RESPONSE 33 288 0.0001454 0.001337
507 REGULATION OF MYELOID CELL DIFFERENTIATION 24 183 0.0001513 0.001389
508 REGULATION OF PROTEIN SECRETION 41 389 0.0001582 0.001449
509 CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 9 36 0.000161 0.001471
510 POSITIVE REGULATION OF DEFENSE RESPONSE 39 364 0.0001612 0.001471
511 POSITIVE REGULATION OF INTERLEUKIN 4 PRODUCTION 7 22 0.0001692 0.001529
512 POSITIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 22 162 0.0001692 0.001529
513 CELLULAR RESPONSE TO INTERLEUKIN 6 7 22 0.0001692 0.001529
514 AORTA MORPHOGENESIS 7 22 0.0001692 0.001529
515 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 22 162 0.0001692 0.001529
516 STRIATED MUSCLE CONTRACTION 16 99 0.0001723 0.001554
517 PIGMENT CELL DIFFERENTIATION 8 29 0.0001773 0.001596
518 NOTCH RECEPTOR PROCESSING 6 16 0.0001801 0.001617
519 NEGATIVE REGULATION OF VASCULATURE DEVELOPMENT 14 80 0.0001831 0.001639
520 POSITIVE REGULATION OF LYMPHOCYTE DIFFERENTIATION 14 80 0.0001831 0.001639
521 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 11 53 0.0001881 0.00168
522 REGULATION OF CELL MATRIX ADHESION 15 90 0.000192 0.001708
523 MESONEPHROS DEVELOPMENT 15 90 0.000192 0.001708
524 DIVALENT INORGANIC CATION TRANSPORT 31 268 0.0001924 0.001708
525 POSITIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 19 131 0.0001947 0.001726
526 REGULATION OF TISSUE REMODELING 12 62 0.000196 0.001734
527 CORONARY VASCULATURE DEVELOPMENT 9 37 0.0002019 0.001776
528 GLIAL CELL MIGRATION 9 37 0.0002019 0.001776
529 POSITIVE REGULATION OF ALPHA BETA T CELL DIFFERENTIATION 9 37 0.0002019 0.001776
530 ENDOTHELIAL CELL DEVELOPMENT 10 45 0.0002023 0.001776
531 POSITIVE REGULATION OF NF KAPPAB TRANSCRIPTION FACTOR ACTIVITY 19 132 0.0002153 0.001887
532 SECRETION BY CELL 48 486 0.0002176 0.001903
533 REGULATION OF T HELPER 2 CELL DIFFERENTIATION 5 11 0.0002221 0.001939
534 ALPHA BETA T CELL ACTIVATION 11 54 0.000224 0.001952
535 CELLULAR RESPONSE TO INTERFERON GAMMA 18 122 0.0002286 0.001988
536 REGULATION OF HEART RATE BY CARDIAC CONDUCTION 8 30 0.0002296 0.00199
537 RESPONSE TO OSMOTIC STRESS 12 63 0.0002295 0.00199
538 REGULATION OF OSTEOBLAST PROLIFERATION 7 23 0.0002312 0.001999
539 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 20 144 0.0002426 0.002094
540 REGULATION OF ALPHA BETA T CELL DIFFERENTIATION 10 46 0.0002453 0.002114
541 MYELOID CELL DIFFERENTIATION 24 189 0.0002484 0.002136
542 CELLULAR RESPONSE TO GLUCAGON STIMULUS 9 38 0.0002511 0.002148
543 REGULATION OF CD4 POSITIVE ALPHA BETA T CELL ACTIVATION 9 38 0.0002511 0.002148
544 REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 9 38 0.0002511 0.002148
545 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 28 236 0.0002529 0.00216
546 EMBRYONIC HEART TUBE DEVELOPMENT 13 73 0.0002576 0.002195
547 SYNAPTIC SIGNALING 43 424 0.0002586 0.002195
548 REGULATION OF IMMUNE EFFECTOR PROCESS 43 424 0.0002586 0.002195
549 NEGATIVE REGULATION OF ANOIKIS 6 17 0.0002647 0.002239
550 REGULATION OF ENDOTHELIAL CELL CHEMOTAXIS 6 17 0.0002647 0.002239
551 ADENYLATE CYCLASE MODULATING G PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY 20 145 0.0002664 0.002245
552 NEGATIVE REGULATION OF RESPONSE TO WOUNDING 21 156 0.0002663 0.002245
553 REGULATION OF MUSCLE TISSUE DEVELOPMENT 16 103 0.0002755 0.002318
554 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 15 93 0.0002784 0.002336
555 POSITIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 23 179 0.0002787 0.002336
556 REGULATION OF AXONOGENESIS 22 168 0.0002862 0.002395
557 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 19 135 0.0002891 0.002415
558 RESPONSE TO REACTIVE OXYGEN SPECIES 24 191 0.0002912 0.002428
559 REGULATION OF INTERLEUKIN 4 PRODUCTION 8 31 0.0002939 0.002442
560 NEGATIVE REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 8 31 0.0002939 0.002442
561 ACTIVATION OF IMMUNE RESPONSE 43 427 0.0003008 0.002495
562 NEGATIVE REGULATION OF GENE EXPRESSION 118 1493 0.0003016 0.002497
563 FOCAL ADHESION ASSEMBLY 7 24 0.0003101 0.002545
564 NEGATIVE REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 7 24 0.0003101 0.002545
565 CELLULAR RESPONSE TO PROSTAGLANDIN STIMULUS 7 24 0.0003101 0.002545
566 REGULATION OF SYSTEMIC ARTERIAL BLOOD PRESSURE 14 84 0.0003107 0.002545
567 CELL SUBSTRATE ADHERENS JUNCTION ASSEMBLY 7 24 0.0003101 0.002545
568 REGULATION OF ANOIKIS 7 24 0.0003101 0.002545
569 SECRETION 55 588 0.0003139 0.002558
570 REGULATION OF CYTOKINE BIOSYNTHETIC PROCESS 15 94 0.0003139 0.002558
571 OUTFLOW TRACT MORPHOGENESIS 11 56 0.0003134 0.002558
572 NEGATIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 19 136 0.0003182 0.002589
573 REGULATION OF MUSCLE CONTRACTION 20 147 0.0003202 0.0026
574 REGULATION OF CYTOPLASMIC TRANSPORT 47 481 0.0003211 0.002603
575 RESPONSE TO INTERLEUKIN 1 17 115 0.0003298 0.002669
576 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 32 289 0.0003379 0.00273
577 REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 13 75 0.0003396 0.002738
578 RESPONSE TO OXIDATIVE STRESS 37 352 0.0003413 0.002747
579 REGULATION OF JNK CASCADE 21 159 0.0003464 0.002784
580 PEPTIDYL SERINE MODIFICATION 20 148 0.0003505 0.002812
581 MYOFIBRIL ASSEMBLY 10 48 0.0003542 0.002837
582 ION TRANSPORT 102 1262 0.0003599 0.00287
583 NEURON PROJECTION EXTENSION INVOLVED IN NEURON PROJECTION GUIDANCE 5 12 0.0003627 0.00287
584 REGULATION OF VITAMIN METABOLIC PROCESS 5 12 0.0003627 0.00287
585 AXON EXTENSION INVOLVED IN AXON GUIDANCE 5 12 0.0003627 0.00287
586 REGULATION OF VASOCONSTRICTION 12 66 0.0003608 0.00287
587 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 5 12 0.0003627 0.00287
588 RENAL FILTRATION 5 12 0.0003627 0.00287
589 ANTERIOR POSTERIOR PATTERN SPECIFICATION 24 194 0.0003676 0.002904
590 REGULATION OF ORGAN FORMATION 8 32 0.0003722 0.002925
591 PATTERNING OF BLOOD VESSELS 8 32 0.0003722 0.002925
592 NEGATIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 8 32 0.0003722 0.002925
593 CELLULAR RESPONSE TO PROSTAGLANDIN E STIMULUS 6 18 0.0003776 0.002953
594 POSITIVE REGULATION OF T HELPER CELL DIFFERENTIATION 6 18 0.0003776 0.002953
595 PERICARDIUM DEVELOPMENT 6 18 0.0003776 0.002953
596 DEVELOPMENTAL PIGMENTATION 9 40 0.0003795 0.002958
597 NEGATIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 9 40 0.0003795 0.002958
598 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 119 1517 0.0003804 0.00296
599 REGULATION OF CYTOKINE SECRETION 20 149 0.0003833 0.002977
600 NEGATIVE REGULATION OF CELL CELL ADHESION 19 138 0.0003841 0.002979
601 EXTRACELLULAR MATRIX DISASSEMBLY 13 76 0.0003883 0.003006
602 MYELOID LEUKOCYTE DIFFERENTIATION 15 96 0.0003965 0.003051
603 ANTIGEN RECEPTOR MEDIATED SIGNALING PATHWAY 24 195 0.0003967 0.003051
604 EAR DEVELOPMENT 24 195 0.0003967 0.003051
605 POSITIVE REGULATION OF CYTOKINE SECRETION 15 96 0.0003965 0.003051
606 REGULATION OF CELL SIZE 22 172 0.0003992 0.00306
607 G PROTEIN COUPLED RECEPTOR SIGNALING PATHWAY COUPLED TO CYCLIC NUCLEOTIDE SECOND MESSENGER 22 172 0.0003992 0.00306
608 POSITIVE REGULATION OF MAP KINASE ACTIVITY 25 207 0.0004048 0.003098
609 REGULATION OF RECEPTOR ACTIVITY 17 117 0.0004056 0.003099
610 CELLULAR EXTRAVASATION 7 25 0.0004094 0.003123
611 CELLULAR RESPONSE TO OXIDATIVE STRESS 23 184 0.0004158 0.003167
612 REGULATION OF TOLL LIKE RECEPTOR SIGNALING PATHWAY 10 49 0.0004223 0.00321
613 NEGATIVE REGULATION OF WOUND HEALING 11 58 0.0004311 0.003272
614 ACTOMYOSIN STRUCTURE ORGANIZATION 13 77 0.0004428 0.003355
615 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 17 118 0.0004488 0.003395
616 REGULATION OF INFLAMMATORY RESPONSE 32 294 0.0004573 0.003454
617 REGULATION OF CAMP METABOLIC PROCESS 18 129 0.0004593 0.003464
618 REGULATION OF MEMBRANE DEPOLARIZATION 9 41 0.0004615 0.003475
619 NEURON RECOGNITION 8 33 0.0004666 0.003502
620 RESPONSE TO VITAMIN D 8 33 0.0004666 0.003502
621 PHOSPHORYLATION 99 1228 0.0004787 0.003587
622 PEPTIDYL TYROSINE MODIFICATION 23 186 0.0004854 0.003631
623 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 15 98 0.0004971 0.003713
624 REGULATION OF HORMONE LEVELS 46 478 0.0005156 0.003845
625 ATRIOVENTRICULAR VALVE DEVELOPMENT 6 19 0.000525 0.003909
626 DEFENSE RESPONSE TO VIRUS 21 164 0.0005273 0.003918
627 POSITIVE REGULATION OF LEUKOCYTE MIGRATION 16 109 0.0005288 0.003918
628 POSITIVE REGULATION OF CYCLIC NUCLEOTIDE METABOLIC PROCESS 16 109 0.0005288 0.003918
629 REGULATION OF T HELPER CELL DIFFERENTIATION 7 26 0.0005324 0.00392
630 RESPONSE TO INTERLEUKIN 6 7 26 0.0005324 0.00392
631 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 65 740 0.0005301 0.00392
632 POSITIVE REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION 7 26 0.0005324 0.00392
633 POSITIVE REGULATION OF PROTEIN SECRETION 25 211 0.0005397 0.003955
634 SKIN DEVELOPMENT 25 211 0.0005397 0.003955
635 NEGATIVE REGULATION OF CYTOKINE PRODUCTION 25 211 0.0005397 0.003955
636 EXTRINSIC APOPTOTIC SIGNALING PATHWAY 15 99 0.0005551 0.004061
637 REGULATION OF RESPIRATORY GASEOUS EXCHANGE BY NEUROLOGICAL SYSTEM PROCESS 5 13 0.0005613 0.004087
638 PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 5 13 0.0005613 0.004087
639 CARDIOBLAST DIFFERENTIATION 5 13 0.0005613 0.004087
640 IMMUNE RESPONSE REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 34 323 0.0005677 0.004127
641 SEGMENTATION 14 89 0.000571 0.004145
642 ADHERENS JUNCTION ASSEMBLY 8 34 0.0005795 0.004187
643 RESPONSE TO PROSTAGLANDIN 8 34 0.0005795 0.004187
644 CAMP METABOLIC PROCESS 8 34 0.0005795 0.004187
645 REGULATION OF SMOOTH MUSCLE CONTRACTION 11 60 0.0005836 0.00421
646 REGULATION OF NEUROTRANSMITTER SECRETION 10 51 0.0005911 0.004238
647 IN UTERO EMBRYONIC DEVELOPMENT 33 311 0.0005904 0.004238
648 NEGATIVE REGULATION OF CHEMOTAXIS 10 51 0.0005911 0.004238
649 CELLULAR RESPONSE TO FATTY ACID 10 51 0.0005911 0.004238
650 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 148 1977 0.0005932 0.004246
651 RAS PROTEIN SIGNAL TRANSDUCTION 19 143 0.0006028 0.004309
652 REGULATION OF CELLULAR COMPONENT SIZE 35 337 0.0006068 0.004331
653 MUSCLE ORGAN MORPHOGENESIS 12 70 0.0006301 0.004483
654 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 12 70 0.0006301 0.004483
655 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 19 144 0.0006576 0.004664
656 REGULATION OF RESPONSE TO CYTOKINE STIMULUS 19 144 0.0006576 0.004664
657 POSITIVE REGULATION OF PURINE NUCLEOTIDE METABOLIC PROCESS 18 133 0.0006657 0.004707
658 POSITIVE REGULATION OF NUCLEOTIDE METABOLIC PROCESS 18 133 0.0006657 0.004707
659 NEGATIVE REGULATION OF STEM CELL DIFFERENTIATION 9 43 0.0006694 0.004719
660 CEREBRAL CORTEX CELL MIGRATION 9 43 0.0006694 0.004719
661 REGULATION OF KERATINOCYTE DIFFERENTIATION 7 27 0.0006831 0.004801
662 SUBSTRATE DEPENDENT CELL MIGRATION 7 27 0.0006831 0.004801
663 REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION 15 101 0.0006886 0.004825
664 REGULATION OF EXTENT OF CELL GROWTH 15 101 0.0006886 0.004825
665 POSITIVE REGULATION OF IMMUNE EFFECTOR PROCESS 20 156 0.0006969 0.004876
666 NEGATIVE REGULATION OF CELL JUNCTION ASSEMBLY 6 20 0.0007136 0.004963
667 RESPONSE TO PROTOZOAN 6 20 0.0007136 0.004963
668 MELANOCYTE DIFFERENTIATION 6 20 0.0007136 0.004963
669 NEGATIVE REGULATION OF CHONDROCYTE DIFFERENTIATION 6 20 0.0007136 0.004963
670 REGULATION OF PROTEIN LOCALIZATION 79 950 0.0007335 0.005094
671 NEGATIVE REGULATION OF HOMOTYPIC CELL CELL ADHESION 15 102 0.0007649 0.005304
672 NEGATIVE REGULATION OF SYNAPTIC TRANSMISSION 11 62 0.0007788 0.005384
673 CARDIAC VENTRICLE MORPHOGENESIS 11 62 0.0007788 0.005384
674 POSITIVE REGULATION OF INFLAMMATORY RESPONSE 16 113 0.0007914 0.005464
675 POSITIVE REGULATION OF PHOSPHOLIPASE ACTIVITY 10 53 0.0008121 0.005598
676 ANGIOGENESIS INVOLVED IN WOUND HEALING 5 14 0.0008317 0.005725
677 REGULATION OF MUSCLE ORGAN DEVELOPMENT 15 103 0.0008484 0.005831
678 PURINERGIC RECEPTOR SIGNALING PATHWAY 7 28 0.0008658 0.005942
679 NEGATIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 8 36 0.0008714 0.005948
680 CELLULAR RESPONSE TO HEAT 8 36 0.0008714 0.005948
681 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 25 218 0.0008718 0.005948
682 LAMELLIPODIUM ORGANIZATION 8 36 0.0008714 0.005948
683 REGULATION OF OSTEOCLAST DIFFERENTIATION 11 63 0.000895 0.00607
684 REGULATION OF EPIDERMIS DEVELOPMENT 11 63 0.000895 0.00607
685 NEUROEPITHELIAL CELL DIFFERENTIATION 11 63 0.000895 0.00607
686 NEGATIVE REGULATION OF NUCLEOTIDE METABOLIC PROCESS 11 63 0.000895 0.00607
687 NEGATIVE REGULATION OF HYDROLASE ACTIVITY 39 397 0.0009034 0.006119
688 REGULATION OF LIPASE ACTIVITY 13 83 0.0009247 0.006254
689 POSITIVE REGULATION OF STAT CASCADE 12 73 0.0009284 0.006261
690 POSITIVE REGULATION OF JAK STAT CASCADE 12 73 0.0009284 0.006261
691 REGULATION OF INTERLEUKIN 6 PRODUCTION 15 104 0.0009394 0.006325
692 ALPHA BETA T CELL DIFFERENTIATION 9 45 0.000948 0.006329
693 THYMOCYTE AGGREGATION 9 45 0.000948 0.006329
694 VENTRICULAR SEPTUM DEVELOPMENT 10 54 0.0009458 0.006329
695 REGULATION OF EPIDERMAL CELL DIFFERENTIATION 9 45 0.000948 0.006329
696 T CELL DIFFERENTIATION IN THYMUS 9 45 0.000948 0.006329
697 SMOOTH MUSCLE CONTRACTION 9 45 0.000948 0.006329
698 POSITIVE T CELL SELECTION 6 21 0.0009504 0.006336
699 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 55 616 0.0009518 0.006336
700 REGULATION OF NEUROTRANSMITTER TRANSPORT 11 64 0.001025 0.006814
701 MAINTENANCE OF LOCATION 18 138 0.001032 0.006847
702 CEREBRAL CORTEX DEVELOPMENT 15 105 0.001038 0.006883
703 REGULATION OF ACUTE INFLAMMATORY RESPONSE 12 74 0.001051 0.006955
704 MYOBLAST DIFFERENTIATION 8 37 0.001056 0.00697
705 FEMALE SEX DIFFERENTIATION 16 116 0.001055 0.00697
706 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 24 209 0.001074 0.007079
707 REGULATION OF EXTRACELLULAR MATRIX ORGANIZATION 7 29 0.001085 0.007129
708 POSITIVE REGULATION OF CARTILAGE DEVELOPMENT 7 29 0.001085 0.007129
709 POSITIVE REGULATION OF CALCIUM ION TRANSPORT 15 106 0.001146 0.007501
710 REGULATION OF FAT CELL DIFFERENTIATION 15 106 0.001146 0.007501
711 REGULATION OF INTRACELLULAR TRANSPORT 55 621 0.001145 0.007501
712 TRANSMEMBRANE TRANSPORT 88 1098 0.001168 0.007635
713 REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 11 65 0.001171 0.007639
714 CELL COMMUNICATION BY ELECTRICAL COUPLING 5 15 0.001188 0.007723
715 CHRONIC INFLAMMATORY RESPONSE 5 15 0.001188 0.007723
716 AZOLE TRANSPORT 5 15 0.001188 0.007723
717 ENDOCARDIAL CUSHION MORPHOGENESIS 6 22 0.001243 0.008058
718 PROTEIN LOCALIZATION TO CELL SURFACE 6 22 0.001243 0.008058
719 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 10 56 0.001267 0.008201
720 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 19 152 0.001272 0.008219
721 REGULATED EXOCYTOSIS 25 224 0.001285 0.008295
722 CATION TRANSPORT 67 796 0.001337 0.008619
723 MEMBRANE BIOGENESIS 7 30 0.001345 0.008621
724 POSITIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 7 30 0.001345 0.008621
725 ESTABLISHMENT OF ENDOTHELIAL BARRIER 7 30 0.001345 0.008621
726 LAMELLIPODIUM ASSEMBLY 7 30 0.001345 0.008621
727 REGULATION OF INTERFERON GAMMA PRODUCTION 14 97 0.001362 0.008717
728 NEGATIVE REGULATION OF KINASE ACTIVITY 27 250 0.001376 0.008775
729 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 19 153 0.001375 0.008775
730 GLYCOPROTEIN METABOLIC PROCESS 35 353 0.001377 0.008775
731 REGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS 13 87 0.001445 0.009199
732 REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 12 77 0.001501 0.009527
733 SPHINGOLIPID BIOSYNTHETIC PROCESS 12 77 0.001501 0.009527
734 SENSORY ORGAN MORPHOGENESIS 26 239 0.001506 0.00955
735 TRABECULA MORPHOGENESIS 8 39 0.001519 0.009575
736 CELLULAR RESPONSE TO NUTRIENT 8 39 0.001519 0.009575
737 PLATELET AGGREGATION 8 39 0.001519 0.009575
738 NEGATIVE CHEMOTAXIS 8 39 0.001519 0.009575
739 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 69 829 0.001521 0.009577
740 RESPIRATORY GASEOUS EXCHANGE 9 48 0.001535 0.009629
741 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 9 48 0.001535 0.009629
742 RESPONSE TO GLUCAGON 9 48 0.001535 0.009629
NumGOOverlapSizeP ValueAdj. P Value
1 RECEPTOR BINDING 155 1476 1.376e-13 1.278e-10
2 CALCIUM ION BINDING 90 697 5.515e-13 2.562e-10
3 CYTOKINE BINDING 24 92 2.896e-10 6.959e-08
4 CYTOSKELETAL PROTEIN BINDING 93 819 2.996e-10 6.959e-08
5 ACTIN BINDING 56 393 3.949e-10 7.337e-08
6 GROWTH FACTOR BINDING 27 123 1.518e-09 2.351e-07
7 SIGNAL TRANSDUCER ACTIVITY 158 1731 3.843e-09 5.1e-07
8 PROTEIN COMPLEX BINDING 98 935 6.985e-09 7.21e-07
9 MACROMOLECULAR COMPLEX BINDING 133 1399 6.752e-09 7.21e-07
10 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 47 328 8.5e-09 7.897e-07
11 MOLECULAR FUNCTION REGULATOR 129 1353 9.83e-09 8.302e-07
12 GLYCOSAMINOGLYCAN BINDING 34 205 2.679e-08 2.074e-06
13 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 36 226 3.095e-08 2.212e-06
14 EXTRACELLULAR MATRIX STRUCTURAL CONSTITUENT 19 76 4.354e-08 2.889e-06
15 HEPARIN BINDING 28 157 9.299e-08 5.646e-06
16 CELL ADHESION MOLECULE BINDING 31 186 9.725e-08 5.646e-06
17 EXTRACELLULAR MATRIX BINDING 15 51 1.117e-07 5.803e-06
18 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 70 629 1.124e-07 5.803e-06
19 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 111 1199 5.1e-07 2.494e-05
20 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 18 81 6.6e-07 3.066e-05
21 CORECEPTOR ACTIVITY 12 38 8.907e-07 3.761e-05
22 ENZYME BINDING 148 1737 8.849e-07 3.761e-05
23 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 41 315 1.024e-06 4.136e-05
24 INTEGRIN BINDING 20 105 2.16e-06 8.362e-05
25 REGULATORY REGION NUCLEIC ACID BINDING 80 818 2.832e-06 0.0001022
26 CYTOKINE RECEPTOR BINDING 36 271 2.861e-06 0.0001022
27 COLLAGEN BINDING 15 65 3.381e-06 0.0001163
28 SULFUR COMPOUND BINDING 32 234 5.443e-06 0.0001806
29 METALLOENDOPEPTIDASE ACTIVITY 20 113 6.981e-06 0.0002236
30 PROTEIN KINASE ACTIVITY 65 640 7.345e-06 0.0002274
31 KINASE BINDING 62 606 9.474e-06 0.0002839
32 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 14 64 1.38e-05 0.0003885
33 RECEPTOR ACTIVITY 136 1649 1.369e-05 0.0003885
34 BINDING BRIDGING 25 173 2.191e-05 0.0005986
35 METALLOPEPTIDASE ACTIVITY 26 188 3.297e-05 0.0008751
36 VIRUS RECEPTOR ACTIVITY 14 70 4.027e-05 0.00103
37 SIGNALING RECEPTOR ACTIVITY 116 1393 4.1e-05 0.00103
38 PROTEIN TYROSINE KINASE BINDING 12 54 4.774e-05 0.001167
39 CATION CHANNEL ACTIVITY 35 298 5.621e-05 0.001339
40 CYTOKINE ACTIVITY 28 219 6.996e-05 0.001625
41 METALLOENDOPEPTIDASE INHIBITOR ACTIVITY 6 14 7.465e-05 0.001691
42 VOLTAGE GATED SODIUM CHANNEL ACTIVITY 7 20 8.519e-05 0.001884
43 PROTEASE BINDING 17 104 9.454e-05 0.002043
44 CHEMOKINE BINDING 7 21 0.0001214 0.002507
45 SIALYLTRANSFERASE ACTIVITY 7 21 0.0001214 0.002507
46 BETA AMYLOID BINDING 9 35 0.0001272 0.00257
47 PASSIVE TRANSMEMBRANE TRANSPORTER ACTIVITY 47 464 0.0001405 0.002777
48 GATED CHANNEL ACTIVITY 36 325 0.0001474 0.002852
49 RECEPTOR SIGNALING PROTEIN ACTIVITY 23 172 0.0001538 0.002915
50 CYTOKINE RECEPTOR ACTIVITY 15 89 0.0001689 0.003138
51 TRANSFORMING GROWTH FACTOR BETA BINDING 6 16 0.0001801 0.00328
52 SEQUENCE SPECIFIC DNA BINDING 88 1037 0.0001909 0.003411
53 CHANNEL REGULATOR ACTIVITY 19 131 0.0001947 0.003413
54 PROTEIN TYROSINE KINASE ACTIVITY 23 176 0.0002171 0.003734
55 LAMININ BINDING 8 30 0.0002296 0.003879
56 VOLTAGE GATED ION CHANNEL ACTIVITY 24 190 0.000269 0.004165
57 PROTEIN BINDING INVOLVED IN CELL ADHESION 6 17 0.0002647 0.004165
58 TUBULIN BINDING 31 273 0.0002674 0.004165
59 TRANSMEMBRANE RECEPTOR PROTEIN PHOSPHATASE ACTIVITY 6 17 0.0002647 0.004165
60 PROTEIN DOMAIN SPECIFIC BINDING 58 624 0.0002564 0.004165
61 METAL ION TRANSMEMBRANE TRANSPORTER ACTIVITY 42 417 0.0003504 0.005336
62 KINASE ACTIVITY 73 842 0.0003606 0.005404
63 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 33 303 0.0003715 0.005478
64 GROWTH FACTOR RECEPTOR BINDING 18 129 0.0004593 0.006667
65 PROTEIN KINASE C BINDING 10 50 0.0005008 0.007158
66 X14 3 3 PROTEIN BINDING 6 19 0.000525 0.00739
67 LIPID BINDING 59 657 0.0005483 0.007602
68 ACTIN FILAMENT BINDING 17 121 0.000603 0.008238
69 ENZYME REGULATOR ACTIVITY 80 959 0.0006201 0.008349
70 TRANSCRIPTION FACTOR BINDING 49 524 0.0006562 0.008709
71 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 26 228 0.000756 0.009755
72 DOUBLE STRANDED DNA BINDING 66 764 0.0007476 0.009755
NumGOOverlapSizeP ValueAdj. P Value
1 CELL JUNCTION 146 1151 7.418e-20 4.332e-17
2 INTRINSIC COMPONENT OF PLASMA MEMBRANE 185 1649 3.848e-19 1.124e-16
3 PROTEINACEOUS EXTRACELLULAR MATRIX 67 356 6.463e-18 9.436e-16
4 MEMBRANE REGION 140 1134 5.148e-18 9.436e-16
5 MEMBRANE MICRODOMAIN 59 288 1.019e-17 1.19e-15
6 EXTRACELLULAR MATRIX 70 426 1.899e-15 1.848e-13
7 EXTRACELLULAR MATRIX COMPONENT 34 125 1.521e-14 1.269e-12
8 SIDE OF MEMBRANE 68 428 2.651e-14 1.935e-12
9 PLASMA MEMBRANE PROTEIN COMPLEX 74 510 2.243e-13 1.455e-11
10 CELL SURFACE 96 757 2.65e-13 1.548e-11
11 CELL PROJECTION 174 1786 2.677e-12 1.421e-10
12 PLASMA MEMBRANE REGION 106 929 1.171e-11 5.697e-10
13 NEURON PART 132 1265 1.766e-11 7.659e-10
14 SYNAPSE 91 754 1.836e-11 7.659e-10
15 NEURON PROJECTION 103 942 2.731e-10 1.063e-08
16 ANCHORING JUNCTION 65 489 3.061e-10 1.117e-08
17 CELL SUBSTRATE JUNCTION 56 398 6.389e-10 2.195e-08
18 EXTRACELLULAR SPACE 135 1376 6.785e-10 2.201e-08
19 EXTERNAL SIDE OF PLASMA MEMBRANE 40 238 1.083e-09 3.33e-08
20 SYNAPSE PART 74 610 1.209e-09 3.531e-08
21 BASEMENT MEMBRANE 23 93 2.117e-09 5.888e-08
22 RECEPTOR COMPLEX 48 327 2.656e-09 7.05e-08
23 POSTSYNAPSE 52 378 5.753e-09 1.461e-07
24 GOLGI APPARATUS 135 1445 1.509e-08 3.673e-07
25 SOMATODENDRITIC COMPARTMENT 74 650 1.888e-08 4.411e-07
26 CELL LEADING EDGE 48 350 2.443e-08 5.488e-07
27 COMPLEX OF COLLAGEN TRIMERS 10 23 2.33e-07 5.04e-06
28 PLASMA MEMBRANE RAFT 19 86 3.578e-07 7.462e-06
29 CELL CELL JUNCTION 48 383 3.911e-07 7.877e-06
30 CELL BODY 56 494 1.179e-06 2.295e-05
31 ENDOPLASMIC RETICULUM 139 1631 1.96e-06 3.692e-05
32 PRESYNAPTIC MEMBRANE 14 55 2.046e-06 3.735e-05
33 CELL PROJECTION PART 90 946 2.133e-06 3.775e-05
34 ACTIN CYTOSKELETON 51 444 2.399e-06 4.002e-05
35 COLLAGEN TRIMER 18 88 2.378e-06 4.002e-05
36 CELL CELL CONTACT ZONE 15 64 2.746e-06 4.455e-05
37 SYNAPTIC MEMBRANE 35 261 3.156e-06 4.982e-05
38 GOLGI APPARATUS PART 85 893 4.044e-06 6.215e-05
39 BASAL PART OF CELL 13 51 4.65e-06 6.963e-05
40 FIBRIL 7 14 5.13e-06 7.49e-05
41 ACTOMYOSIN 14 62 9.347e-06 0.0001331
42 RUFFLE 24 156 1.096e-05 0.0001524
43 INTRACELLULAR VESICLE 109 1259 1.398e-05 0.0001898
44 MEMBRANE PROTEIN COMPLEX 92 1020 1.43e-05 0.0001898
45 CYTOPLASMIC SIDE OF MEMBRANE 25 170 1.615e-05 0.0002096
46 DENDRITE 49 451 1.715e-05 0.0002178
47 LAMELLIPODIUM 25 172 1.981e-05 0.0002462
48 GOLGI MEMBRANE 68 703 2.257e-05 0.0002746
49 INTERCALATED DISC 12 51 2.595e-05 0.0003093
50 SARCOLEMMA 20 125 3.253e-05 0.00038
51 PROTEIN COMPLEX INVOLVED IN CELL ADHESION 9 30 3.351e-05 0.0003837
52 CONTRACTILE FIBER 28 211 3.584e-05 0.0004025
53 ENDOPLASMIC RETICULUM LUMEN 27 201 3.954e-05 0.0004357
54 SITE OF POLARIZED GROWTH 22 149 4.793e-05 0.0005184
55 CYTOPLASMIC VESICLE PART 59 601 5.139e-05 0.0005457
56 COSTAMERE 7 19 5.828e-05 0.0006078
57 EXCITATORY SYNAPSE 26 197 7.362e-05 0.0007389
58 VOLTAGE GATED SODIUM CHANNEL COMPLEX 6 14 7.465e-05 0.0007389
59 CLATHRIN COATED ENDOCYTIC VESICLE MEMBRANE 11 48 7.274e-05 0.0007389
60 ACTIN FILAMENT BUNDLE 12 57 8.383e-05 0.000816
61 ENDOPLASMIC RETICULUM PART 98 1163 0.0001074 0.001028
62 VESICLE MEMBRANE 51 512 0.0001135 0.001069
63 ACTIN FILAMENT 13 70 0.0001665 0.001543
64 ENDOCYTIC VESICLE MEMBRANE 21 152 0.0001849 0.001687
65 ENDOCYTIC VESICLE 30 256 0.0001928 0.001732
66 PLASMA MEMBRANE RECEPTOR COMPLEX 23 175 0.0001994 0.001764
67 SODIUM CHANNEL COMPLEX 6 17 0.0002647 0.002307
68 VACUOLE 97 1180 0.0002813 0.002416
69 CLATHRIN COATED ENDOCYTIC VESICLE 12 65 0.0003114 0.002635
70 POSTSYNAPTIC MEMBRANE 25 205 0.0003492 0.002914
71 INTRINSIC COMPONENT OF GOLGI MEMBRANE 11 57 0.0003683 0.00303
72 ENDOSOME 69 793 0.0004697 0.00381
73 EXTRINSIC COMPONENT OF CYTOPLASMIC SIDE OF PLASMA MEMBRANE 15 98 0.0004971 0.003977
74 I BAND 17 121 0.000603 0.004759
75 RUFFLE MEMBRANE 13 80 0.0006467 0.005036
76 CATION CHANNEL COMPLEX 21 167 0.0006713 0.005158
77 BASAL LAMINA 6 21 0.0009504 0.007116
78 T TUBULE 9 45 0.000948 0.007116
79 PRESYNAPSE 30 283 0.00104 0.007688
80 APICAL PART OF CELL 36 361 0.001071 0.007816

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Focal_adhesion_hsa04510 42 199 1.861e-13 9.679e-12
2 PI3K_Akt_signaling_pathway_hsa04151 58 352 4.562e-13 1.186e-11
3 Cytokine_cytokine_receptor_interaction_hsa04060 45 270 1.316e-10 2.281e-09
4 Cell_adhesion_molecules_.CAMs._hsa04514 29 145 3.757e-09 4.884e-08
5 ECM_receptor_interaction_hsa04512 21 82 5.357e-09 5.571e-08
6 Rap1_signaling_pathway_hsa04015 35 206 8.852e-09 7.672e-08
7 MAPK_signaling_pathway_hsa04010 43 295 2.195e-08 1.631e-07
8 Apelin_signaling_pathway_hsa04371 26 137 7.305e-08 4.748e-07
9 Jak_STAT_signaling_pathway_hsa04630 27 162 6.419e-07 3.709e-06
10 cGMP_PKG_signaling_pathway_hsa04022 27 163 7.276e-07 3.784e-06
11 Ras_signaling_pathway_hsa04014 33 232 1.628e-06 7.696e-06
12 Adherens_junction_hsa04520 16 72 2.734e-06 1.185e-05
13 Regulation_of_actin_cytoskeleton_hsa04810 30 208 3.585e-06 1.434e-05
14 HIF_1_signaling_pathway_hsa04066 17 100 5.693e-05 0.0002115
15 Phospholipase_D_signaling_pathway_hsa04072 21 146 0.0001037 0.0003594
16 Gap_junction_hsa04540 15 88 0.0001482 0.0004818
17 cAMP_signaling_pathway_hsa04024 25 198 0.0002039 0.0006236
18 Sphingolipid_signaling_pathway_hsa04071 17 118 0.0004488 0.001296
19 ABC_transporters_hsa02010 9 45 0.000948 0.002595
20 TNF_signaling_pathway_hsa04668 15 108 0.00139 0.003615
21 Hippo_signaling_pathway_hsa04390 19 154 0.001486 0.003679
22 Calcium_signaling_pathway_hsa04020 20 182 0.004456 0.01053
23 Hippo_signaling_pathway_multiple_species_hsa04392 6 29 0.005597 0.01265
24 NF_kappa_B_signaling_pathway_hsa04064 12 95 0.008635 0.01871
25 FoxO_signaling_pathway_hsa04068 15 132 0.009467 0.01969
26 Notch_signaling_pathway_hsa04330 7 48 0.01973 0.03946
27 TGF_beta_signaling_pathway_hsa04350 10 84 0.02301 0.04432
28 ErbB_signaling_pathway_hsa04012 10 85 0.02478 0.04602
29 Ferroptosis_hsa04216 6 40 0.02641 0.04735
30 Oocyte_meiosis_hsa04114 13 124 0.02746 0.04735
31 Necroptosis_hsa04217 16 164 0.02858 0.04735
32 Apoptosis_hsa04210 14 138 0.02914 0.04735
33 Cellular_senescence_hsa04218 15 160 0.0448 0.0706
34 Neuroactive_ligand_receptor_interaction_hsa04080 23 278 0.05443 0.08325
35 Phagosome_hsa04145 14 152 0.05785 0.08595
36 Endocytosis_hsa04144 20 244 0.07442 0.1075
37 Tight_junction_hsa04530 14 170 0.1168 0.1642
38 Wnt_signaling_pathway_hsa04310 12 146 0.1401 0.1918
39 AMPK_signaling_pathway_hsa04152 10 121 0.1633 0.2178
40 Lysosome_hsa04142 10 123 0.1755 0.2281
41 Hedgehog_signaling_pathway_hsa04340 4 47 0.2886 0.366
42 Autophagy_animal_hsa04140 9 128 0.3231 0.4
43 Mitophagy_animal_hsa04137 4 65 0.524 0.6257
44 Peroxisome_hsa04146 5 83 0.5294 0.6257
45 p53_signaling_pathway_hsa04115 4 68 0.56 0.6471
46 Apoptosis_multiple_species_hsa04215 2 33 0.5772 0.6525
47 mTOR_signaling_pathway_hsa04150 8 151 0.6524 0.7218
48 VEGF_signaling_pathway_hsa04370 3 59 0.6718 0.7278
49 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 7 139 0.7007 0.7436
50 Cell_cycle_hsa04110 6 124 0.7303 0.7595
51 Phosphatidylinositol_signaling_system_hsa04070 4 99 0.8321 0.8484

Quest ID: 5ef71f852cb5e3e74d922ca5262849ac