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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-200c-3p ABL2 3.5 0 -0.32 0.04554 MirTarget -0.15 0 NA
2 hsa-miR-200c-3p ACTC1 3.5 0 -7.19 0 MirTarget -1.34 0 NA
3 hsa-miR-200c-3p ADAMTS3 3.5 0 -1.18 0.00448 miRNATAP -0.41 0 NA
4 hsa-miR-200c-3p ADCY2 3.5 0 -3.87 0 MirTarget; miRNATAP -0.44 0 NA
5 hsa-miR-200c-3p AFF3 3.5 0 -5 0 MirTarget; miRNATAP -0.59 0 NA
6 hsa-miR-200c-3p AMOTL2 3.5 0 -1.01 0.00015 MirTarget; miRNATAP -0.22 0 NA
7 hsa-miR-200c-3p ANKH 3.5 0 -0.38 0.21654 miRNATAP -0.29 0 NA
8 hsa-miR-200c-3p AP1S2 3.5 0 -1.31 0 MirTarget; miRNATAP -0.38 0 NA
9 hsa-miR-200c-3p ARHGAP20 3.5 0 -3.52 0 MirTarget; miRNATAP -0.51 0 NA
10 hsa-miR-200c-3p ARHGAP28 3.5 0 -1.54 0.00053 MirTarget -0.2 1.0E-5 NA
11 hsa-miR-200c-3p ARHGAP6 3.5 0 -3.25 0 MirTarget -0.12 0.0192 NA
12 hsa-miR-200c-3p ARHGEF17 3.5 0 -1.19 0 miRNATAP -0.24 0 NA
13 hsa-miR-200c-3p ARL10 3.5 0 -1.12 0.00198 mirMAP -0.29 0 NA
14 hsa-miR-200c-3p ASAP1 3.5 0 0.06 0.77944 MirTarget; miRNATAP -0.16 0 NA
15 hsa-miR-200c-3p ATXN1 3.5 0 -1.51 0 MirTarget; miRNATAP -0.24 0 NA
16 hsa-miR-200c-3p BACH2 3.5 0 -1.52 0.00134 mirMAP -0.54 0 NA
17 hsa-miR-200c-3p BASP1 3.5 0 -0.12 0.79725 miRNATAP -0.19 6.0E-5 NA
18 hsa-miR-200c-3p BCL2 3.5 0 -2.02 0 miRNAWalker2 validate; miRTarBase; mirMAP -0.19 0 NA
19 hsa-miR-200c-3p BEND4 3.5 0 -1.97 7.0E-5 mirMAP -0.32 0 NA
20 hsa-miR-200c-3p BNC2 3.5 0 -2.95 0 MirTarget -0.7 0 NA
21 hsa-miR-200c-3p C11orf87 3.5 0 -1.55 0.01186 miRNATAP -0.34 0 NA
22 hsa-miR-200c-3p C17orf51 3.5 0 -0.68 0.02254 mirMAP -0.28 0 NA
23 hsa-miR-200c-3p CACNA1C 3.5 0 -2.53 0 MirTarget -0.44 0 NA
24 hsa-miR-200c-3p CALU 3.5 0 -0.15 0.46318 MirTarget -0.23 0 NA
25 hsa-miR-200c-3p CBL 3.5 0 -0.31 0.06484 MirTarget; mirMAP -0.11 0 NA
26 hsa-miR-200c-3p CDK6 3.5 0 -0.77 0.06479 mirMAP -0.32 0 NA
27 hsa-miR-200c-3p CELF2 3.5 0 -3.05 0 mirMAP; miRNATAP -0.51 0 NA
28 hsa-miR-200c-3p CFL2 3.5 0 -2.62 0 MirTarget; miRNATAP -0.48 0 23497265 We characterized one of the target genes of miR-200c CFL2 and demonstrated that CFL2 is overexpressed in aggressive breast cancer cell lines and can be significantly down-regulated by exogenous miR-200c
29 hsa-miR-200c-3p CHRDL1 3.5 0 -6.15 0 MirTarget -0.99 0 NA
30 hsa-miR-200c-3p CHST11 3.5 0 0.54 0.2311 mirMAP -0.4 0 NA
31 hsa-miR-200c-3p CIITA 3.5 0 -0.02 0.95968 mirMAP -0.2 2.0E-5 NA
32 hsa-miR-200c-3p CLIC4 3.5 0 -1.72 0 MirTarget; miRNATAP -0.46 0 NA
33 hsa-miR-200c-3p CLIP2 3.5 0 -0.8 0.00158 MirTarget; miRNATAP -0.18 0 NA
34 hsa-miR-200c-3p CNN3 3.5 0 -0.66 0.00535 MirTarget; miRNATAP -0.2 0 NA
35 hsa-miR-200c-3p CNTFR 3.5 0 -3.86 0 miRNATAP -0.44 0 NA
36 hsa-miR-200c-3p CNTN1 3.5 0 -4.98 0 MirTarget; miRNATAP -0.74 0 NA
37 hsa-miR-200c-3p CNTN4 3.5 0 -3.06 0 miRNATAP -0.19 5.0E-5 NA
38 hsa-miR-200c-3p COL4A3 3.5 0 -3.14 0 miRNATAP -0.32 0 NA
39 hsa-miR-200c-3p COPS8 3.5 0 -0.27 0.01391 MirTarget -0.11 0 NA
40 hsa-miR-200c-3p CORO1C 3.5 0 -1.12 0 MirTarget; miRNATAP -0.29 0 NA
41 hsa-miR-200c-3p CREB5 3.5 0 -2.28 0 miRNATAP -0.47 0 NA
42 hsa-miR-200c-3p CYP1B1 3.5 0 -2.82 0 miRNATAP -0.55 0 25860934 Loss of miR 200c up regulates CYP1B1 and confers docetaxel resistance in renal cell carcinoma; Additionally miR-200c which is significantly down-regulated in RCC regulates CYP1B1 expression and activity; An inverse association was also observed between the expression levels of miR-200c and CYP1B1 protein in RCC tissues; Restoration of docetaxel resistance by exogenous expression of CYP1B1 in miR-200c-over-expressing cells indicates that CYP1B1 is a functional target of miR-200c; These results suggest that CYP1B1 up-regulation mediated by low miR-200c is one of the mechanisms underlying resistance of RCC cells to docetaxel; Therefore expression of CYP1B1 and miR-200c in RCC may be useful as a prediction for docetaxel response
43 hsa-miR-200c-3p CYTH3 3.5 0 -0.27 0.19343 MirTarget -0.17 0 NA
44 hsa-miR-200c-3p DACT1 3.5 0 -1.78 2.0E-5 miRNATAP -0.47 0 NA
45 hsa-miR-200c-3p DCBLD2 3.5 0 -0.13 0.73597 MirTarget -0.31 0 NA
46 hsa-miR-200c-3p DDIT4L 3.5 0 -1.9 0.00047 MirTarget -0.47 0 NA
47 hsa-miR-200c-3p DENND5A 3.5 0 -1.19 0 MirTarget -0.25 0 NA
48 hsa-miR-200c-3p DENND5B 3.5 0 -1.35 0.0001 MirTarget; miRNATAP -0.39 0 NA
49 hsa-miR-200c-3p DIAPH2 3.5 0 -0.89 0.00037 mirMAP -0.11 4.0E-5 NA
50 hsa-miR-200c-3p DIXDC1 3.5 0 -3.01 0 MirTarget -0.52 0 NA
51 hsa-miR-200c-3p DLC1 3.5 0 -1.8 0 miRNATAP -0.2 0 NA
52 hsa-miR-200c-3p DMD 3.5 0 -3.69 0 miRNATAP -0.53 0 NA
53 hsa-miR-200c-3p DNAJB5 3.5 0 -2.65 0 miRNATAP -0.52 0 NA
54 hsa-miR-200c-3p DOCK4 3.5 0 -0.48 0.07912 MirTarget -0.22 0 NA
55 hsa-miR-200c-3p DRP2 3.5 0 -1.35 0.00023 mirMAP -0.31 0 NA
56 hsa-miR-200c-3p DST 3.5 0 -1.12 9.0E-5 mirMAP -0.1 0.00054 NA
57 hsa-miR-200c-3p DTNA 3.5 0 -4.06 0 MirTarget -0.65 0 NA
58 hsa-miR-200c-3p DUSP1 3.5 0 -3.47 0 MirTarget; miRNATAP -0.32 0 NA
59 hsa-miR-200c-3p DYNC1I1 3.5 0 -2.05 0.0001 MirTarget -0.2 0.00038 NA
60 hsa-miR-200c-3p DZIP1 3.5 0 -1.57 2.0E-5 MirTarget -0.34 0 NA
61 hsa-miR-200c-3p EDNRA 3.5 0 -2.19 0 miRNAWalker2 validate; miRNATAP -0.43 0 NA
62 hsa-miR-200c-3p ELL2 3.5 0 -1.08 1.0E-5 MirTarget -0.13 0 NA
63 hsa-miR-200c-3p ENTPD1 3.5 0 -1.12 0 MirTarget; mirMAP -0.24 0 NA
64 hsa-miR-200c-3p ERC1 3.5 0 -1.1 0 mirMAP -0.17 0 NA
65 hsa-miR-200c-3p ETS1 3.5 0 -0.7 0.00228 MirTarget; miRNATAP -0.13 0 NA
66 hsa-miR-200c-3p ETV5 3.5 0 0.24 0.42305 MirTarget; miRNATAP -0.2 0 27276064 Another study suggested that ERM expression was regulated directly by miR-200c and had a critical role in miR-200c suppressing cell migration
67 hsa-miR-200c-3p EXT1 3.5 0 0.13 0.57371 mirMAP -0.12 0 NA
68 hsa-miR-200c-3p F2RL2 3.5 0 -0.07 0.88286 MirTarget -0.4 0 NA
69 hsa-miR-200c-3p FAT3 3.5 0 -2.79 0 MirTarget; miRNATAP -0.23 0.00025 NA
70 hsa-miR-200c-3p FBLN5 3.5 0 -2.76 0 miRNAWalker2 validate; miRTarBase -0.4 0 NA
71 hsa-miR-200c-3p FGD1 3.5 0 -0.05 0.85964 miRNATAP -0.18 0 NA
72 hsa-miR-200c-3p FGF18 3.5 0 -1.42 0.00104 miRNATAP -0.26 0 NA
73 hsa-miR-200c-3p FGF2 3.5 0 -3.46 0 mirMAP -0.58 0 NA
74 hsa-miR-200c-3p FHL1 3.5 0 -4.79 0 MirTarget -0.78 0 NA
75 hsa-miR-200c-3p FHOD1 3.5 0 0.61 0.00071 miRNAWalker2 validate -0.11 0 22144583 MicroRNA 200c represses migration and invasion of breast cancer cells by targeting actin regulatory proteins FHOD1 and PPM1F; We identified FHOD1 and PPM1F direct regulators of the actin cytoskeleton as novel targets of miR-200c; Remarkably expression levels of FHOD1 and PPM1F were inversely correlated with the level of miR-200c in breast cancer cell lines breast cancer patient samples and 58 cancer cell lines of various origins
76 hsa-miR-200c-3p FKBP14 3.5 0 0.03 0.86788 mirMAP -0.12 0 NA
77 hsa-miR-200c-3p FLI1 3.5 0 -1.11 7.0E-5 MirTarget; miRNATAP -0.32 0 NA
78 hsa-miR-200c-3p FLNA 3.5 0 -2.63 0 miRNAWalker2 validate -0.57 0 NA
79 hsa-miR-200c-3p FN1 3.5 0 -0.41 0.45793 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.66 0 NA
80 hsa-miR-200c-3p FOXF1 3.5 0 -3.6 0 MirTarget -0.33 0 NA
81 hsa-miR-200c-3p FSTL1 3.5 0 -1.2 3.0E-5 MirTarget -0.36 0 NA
82 hsa-miR-200c-3p FUNDC2 3.5 0 -0.54 1.0E-5 mirMAP -0.12 0 NA
83 hsa-miR-200c-3p FYN 3.5 0 -1.47 0 miRNATAP -0.35 0 NA
84 hsa-miR-200c-3p FZD4 3.5 0 -0.83 0.00068 mirMAP -0.11 1.0E-5 NA
85 hsa-miR-200c-3p GATA4 3.5 0 0.21 0.73605 MirTarget; miRNATAP -0.25 0.00011 NA
86 hsa-miR-200c-3p GEM 3.5 0 -3.69 0 MirTarget; miRNATAP -0.6 0 NA
87 hsa-miR-200c-3p GFI1 3.5 0 0.35 0.37482 miRNATAP -0.14 0.00083 NA
88 hsa-miR-200c-3p GFRA1 3.5 0 -5 0 mirMAP -0.33 0 NA
89 hsa-miR-200c-3p GJA3 3.5 0 0.72 0.20501 mirMAP -0.16 0.00815 NA
90 hsa-miR-200c-3p GJC1 3.5 0 -0.97 0.00222 MirTarget; miRNATAP -0.31 0 NA
91 hsa-miR-200c-3p GLI3 3.5 0 -0.85 0.02024 miRNATAP -0.22 0 NA
92 hsa-miR-200c-3p GLIS2 3.5 0 -0.61 0.05279 miRNATAP -0.31 0 NA
93 hsa-miR-200c-3p GLRX 3.5 0 -0.28 0.31677 MirTarget -0.17 0 NA
94 hsa-miR-200c-3p GNG4 3.5 0 0.22 0.74468 mirMAP -0.42 0 NA
95 hsa-miR-200c-3p GPM6A 3.5 0 -4.43 0 miRNATAP -0.61 0 NA
96 hsa-miR-200c-3p GPR146 3.5 0 -1.49 0 miRNATAP -0.18 0 NA
97 hsa-miR-200c-3p GPRASP2 3.5 0 -1.46 0 MirTarget -0.18 0 NA
98 hsa-miR-200c-3p GREM1 3.5 0 0.09 0.91453 MirTarget -0.65 0 NA
99 hsa-miR-200c-3p HCFC2 3.5 0 -0.81 0 miRNATAP -0.12 0 NA
100 hsa-miR-200c-3p HDAC4 3.5 0 -1.8 0 miRNATAP -0.26 0 NA
101 hsa-miR-200c-3p HIPK3 3.5 0 -1.75 0 MirTarget -0.18 0 NA
102 hsa-miR-200c-3p HIVEP3 3.5 0 0.03 0.92033 miRNATAP -0.21 0 NA
103 hsa-miR-200c-3p HLF 3.5 0 -5.48 0 MirTarget; miRNATAP -0.6 0 NA
104 hsa-miR-200c-3p HPS5 3.5 0 -0.39 0.01461 MirTarget -0.12 0 NA
105 hsa-miR-200c-3p HS3ST3A1 3.5 0 -0.13 0.83157 MirTarget -0.63 0 NA
106 hsa-miR-200c-3p HUNK 3.5 0 -2.27 1.0E-5 mirMAP -0.23 2.0E-5 NA
107 hsa-miR-200c-3p IFIT5 3.5 0 -0.14 0.54951 miRNATAP -0.13 0 NA
108 hsa-miR-200c-3p IGSF10 3.5 0 -5.3 0 MirTarget -0.54 0 NA
109 hsa-miR-200c-3p IL6ST 3.5 0 -2.1 2.0E-5 mirMAP -0.35 0 NA
110 hsa-miR-200c-3p ITGA1 3.5 0 -1.43 0 MirTarget -0.34 0 NA
111 hsa-miR-200c-3p ITPR1 3.5 0 -2.58 0 miRNATAP -0.31 0 NA
112 hsa-miR-200c-3p ITPR2 3.5 0 -0.18 0.43611 MirTarget -0.15 0 NA
113 hsa-miR-200c-3p JAZF1 3.5 0 -1.92 0 MirTarget; miRNATAP -0.42 0 NA
114 hsa-miR-200c-3p JUN 3.5 0 -2.05 0 MirTarget -0.2 0 NA
115 hsa-miR-200c-3p KCNJ2 3.5 0 -0.28 0.36165 miRNATAP -0.12 0.00012 NA
116 hsa-miR-200c-3p KCNK2 3.5 0 -3.96 0 miRNATAP -0.5 0 NA
117 hsa-miR-200c-3p KCNQ4 3.5 0 -2.64 0 miRNATAP -0.36 0 NA
118 hsa-miR-200c-3p KCTD15 3.5 0 -1.07 0.00367 MirTarget; miRNATAP -0.22 0 NA
119 hsa-miR-200c-3p KDR 3.5 0 -0.81 0.0014 miRNATAP -0.1 0.00017 24205206 MiR 200c increases the radiosensitivity of non small cell lung cancer cell line A549 by targeting VEGF VEGFR2 pathway; MiR-200c at the nexus of epithelial-mesenchymal transition EMT is predicted to target VEGFR2; The purpose of this study is to test the hypothesis that regulation of VEGFR2 pathway by miR-200c could modulate the radiosensitivity of cancer cells; Bioinformatic analysis luciferase reporter assays and biochemical assays were carried out to validate VEGFR2 as a direct target of miR-200c; We identified VEGFR2 as a novel target of miR-200c
120 hsa-miR-200c-3p KIAA1462 3.5 0 -1.72 0 MirTarget -0.39 0 NA
121 hsa-miR-200c-3p KIF13A 3.5 0 -1.22 0 miRNATAP -0.12 0 NA
122 hsa-miR-200c-3p KLF10 3.5 0 -1.13 0 miRNATAP -0.18 0 NA
123 hsa-miR-200c-3p KLF11 3.5 0 -0.89 1.0E-5 miRNAWalker2 validate -0.11 0 NA
124 hsa-miR-200c-3p KLF13 3.5 0 -1.16 1.0E-5 miRNATAP -0.22 0 NA
125 hsa-miR-200c-3p KLF4 3.5 0 -2.67 0 MirTarget; miRNATAP -0.11 0.00217 NA
126 hsa-miR-200c-3p KLF9 3.5 0 -2.79 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.4 0 NA
127 hsa-miR-200c-3p KLHDC1 3.5 0 -1.74 0 MirTarget -0.12 4.0E-5 NA
128 hsa-miR-200c-3p LAMC1 3.5 0 -0.82 0.0001 MirTarget; miRNATAP -0.19 0 NA
129 hsa-miR-200c-3p LATS2 3.5 0 -1.5 0 miRNATAP -0.26 0 NA
130 hsa-miR-200c-3p LHFP 3.5 0 -1.83 0 MirTarget; miRNATAP -0.36 0 NA
131 hsa-miR-200c-3p LIX1L 3.5 0 -1.29 0 MirTarget -0.34 0 NA
132 hsa-miR-200c-3p LPAR1 3.5 0 -1.92 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.18 0 NA
133 hsa-miR-200c-3p LPIN1 3.5 0 -0.9 0.00013 MirTarget -0.17 0 NA
134 hsa-miR-200c-3p MAF 3.5 0 -1.28 0.00016 miRNATAP -0.36 0 NA
135 hsa-miR-200c-3p MAP2 3.5 0 -0.75 0.09708 MirTarget; miRNATAP -0.26 0 NA
136 hsa-miR-200c-3p MARCH1 3.5 0 0.25 0.34759 MirTarget -0.19 0 NA
137 hsa-miR-200c-3p MARCH8 3.5 0 -0.88 0.00115 MirTarget -0.12 2.0E-5 NA
138 hsa-miR-200c-3p MBNL1 3.5 0 -1.04 0 miRNATAP -0.15 0 NA
139 hsa-miR-200c-3p MCFD2 3.5 0 -0.27 0.08021 MirTarget -0.13 0 NA
140 hsa-miR-200c-3p MEF2D 3.5 0 -1.25 0 mirMAP -0.14 0 NA
141 hsa-miR-200c-3p MEGF10 3.5 0 -0.57 0.2307 MirTarget -0.15 0.00326 NA
142 hsa-miR-200c-3p MEX3B 3.5 0 0.13 0.71267 miRNATAP -0.21 0 NA
143 hsa-miR-200c-3p MFAP5 3.5 0 -4.35 0 miRNATAP -0.9 0 NA
144 hsa-miR-200c-3p MITF 3.5 0 -2.11 0 miRNATAP -0.37 0 NA
145 hsa-miR-200c-3p MMD 3.5 0 -0.05 0.87055 miRNATAP -0.31 0 NA
146 hsa-miR-200c-3p MMGT1 3.5 0 -0.69 1.0E-5 MirTarget -0.14 0 NA
147 hsa-miR-200c-3p MPDZ 3.5 0 -1.47 0 MirTarget -0.21 0 NA
148 hsa-miR-200c-3p MRVI1 3.5 0 -3.2 0 MirTarget -0.43 0 NA
149 hsa-miR-200c-3p MSN 3.5 0 -0.86 0.01366 miRNAWalker2 validate; miRTarBase; MirTarget -0.39 0 NA
150 hsa-miR-200c-3p MSRB3 3.5 0 -3.32 0 mirMAP -0.64 0 NA
NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 78 1672 1.392e-20 6.479e-17
2 CELL DEVELOPMENT 66 1426 3.927e-17 9.135e-14
3 REGULATION OF CELL DIFFERENTIATION 67 1492 9.884e-17 1.533e-13
4 REGULATION OF NEURON DIFFERENTIATION 36 554 8.468e-14 9.85e-11
5 REGULATION OF CELL DEVELOPMENT 44 836 2.017e-13 1.877e-10
6 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 48 1021 8.993e-13 6.387e-10
7 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 51 1142 1.098e-12 6.387e-10
8 REGULATION OF CELLULAR COMPONENT MOVEMENT 41 771 1.055e-12 6.387e-10
9 TISSUE DEVELOPMENT 60 1518 1.475e-12 7.628e-10
10 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 40 750 1.874e-12 8.197e-10
11 NEUROGENESIS 57 1402 1.938e-12 8.197e-10
12 POSITIVE REGULATION OF CELL DIFFERENTIATION 41 823 8.405e-12 3.259e-09
13 RESPONSE TO WOUNDING 33 563 1.615e-11 5.781e-09
14 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 51 1275 6.298e-11 2.093e-08
15 NEGATIVE REGULATION OF CELL PROLIFERATION 34 643 1.251e-10 3.881e-08
16 CENTRAL NERVOUS SYSTEM DEVELOPMENT 40 872 1.867e-10 5.43e-08
17 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 61 1784 3.683e-10 1.008e-07
18 REGULATION OF NEURON PROJECTION DEVELOPMENT 26 408 4.404e-10 1.124e-07
19 CELLULAR COMPONENT MORPHOGENESIS 40 900 4.732e-10 1.124e-07
20 CARDIOVASCULAR SYSTEM DEVELOPMENT 37 788 5.075e-10 1.124e-07
21 CIRCULATORY SYSTEM DEVELOPMENT 37 788 5.075e-10 1.124e-07
22 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 29 513 6.878e-10 1.455e-07
23 POSITIVE REGULATION OF GENE EXPRESSION 59 1733 9.057e-10 1.832e-07
24 POSITIVE REGULATION OF NEURON DIFFERENTIATION 22 306 1.101e-09 2.134e-07
25 REGULATION OF CELL PROLIFERATION 53 1496 1.975e-09 3.675e-07
26 POSITIVE REGULATION OF CELL DEVELOPMENT 27 472 2.134e-09 3.818e-07
27 LOCOMOTION 44 1114 2.314e-09 3.987e-07
28 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 34 724 2.711e-09 4.505e-07
29 REGULATION OF CELL PROJECTION ORGANIZATION 29 558 4.657e-09 7.471e-07
30 BIOLOGICAL ADHESION 41 1032 7.395e-09 1.147e-06
31 POSITIVE REGULATION OF MOLECULAR FUNCTION 58 1791 8.192e-09 1.23e-06
32 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 25 437 8.634e-09 1.255e-06
33 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 59 1848 9.945e-09 1.402e-06
34 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 49 1395 1.18e-08 1.615e-06
35 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 33 740 1.661e-08 2.209e-06
36 FOREBRAIN DEVELOPMENT 22 357 1.864e-08 2.344e-06
37 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 39 983 1.861e-08 2.344e-06
38 HEAD DEVELOPMENT 32 709 2.103e-08 2.575e-06
39 HEART DEVELOPMENT 25 466 3.067e-08 3.659e-06
40 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 34 801 3.315e-08 3.857e-06
41 RESPONSE TO ENDOGENOUS STIMULUS 49 1450 3.992e-08 4.53e-06
42 NEURON PROJECTION DEVELOPMENT 27 545 4.385e-08 4.858e-06
43 CELL JUNCTION ASSEMBLY 13 129 6.138e-08 6.632e-06
44 REGULATION OF CELL DEATH 49 1472 6.363e-08 6.632e-06
45 REGULATION OF CELL ADHESION 29 629 6.414e-08 6.632e-06
46 INTRACELLULAR SIGNAL TRANSDUCTION 51 1572 7.392e-08 7.477e-06
47 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 38 1004 9.795e-08 9.698e-06
48 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 38 1008 1.084e-07 1.051e-05
49 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 19 303 1.362e-07 1.293e-05
50 WOUND HEALING 24 470 1.463e-07 1.347e-05
51 EMBRYO DEVELOPMENT 35 894 1.477e-07 1.347e-05
52 NEURON PROJECTION MORPHOGENESIS 22 402 1.509e-07 1.351e-05
53 MESENCHYME DEVELOPMENT 15 190 1.554e-07 1.364e-05
54 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 49 1517 1.593e-07 1.373e-05
55 EPITHELIUM DEVELOPMENT 36 945 1.881e-07 1.591e-05
56 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 16 229 3.194e-07 2.654e-05
57 EPITHELIAL CELL DIFFERENTIATION 24 495 3.76e-07 3.054e-05
58 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 16 232 3.807e-07 3.054e-05
59 NEURON DEVELOPMENT 29 687 4.074e-07 3.107e-05
60 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 54 1805 3.951e-07 3.107e-05
61 POSITIVE REGULATION OF CATALYTIC ACTIVITY 48 1518 4.064e-07 3.107e-05
62 EMBRYONIC MORPHOGENESIS 25 539 4.86e-07 3.647e-05
63 BLOOD VESSEL MORPHOGENESIS 20 364 5.289e-07 3.898e-05
64 VASCULATURE DEVELOPMENT 23 469 5.445e-07 3.898e-05
65 CELL PROJECTION ORGANIZATION 34 902 5.403e-07 3.898e-05
66 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 20 368 6.278e-07 4.426e-05
67 CELL JUNCTION ORGANIZATION 14 185 6.769e-07 4.701e-05
68 REGULATION OF CELL MORPHOGENESIS 25 552 7.525e-07 5.149e-05
69 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 50 1656 8.842e-07 5.962e-05
70 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 31 799 9.713e-07 6.405e-05
71 ORGAN MORPHOGENESIS 32 841 9.773e-07 6.405e-05
72 ACTIN FILAMENT BASED PROCESS 22 450 1.019e-06 6.583e-05
73 REGULATION OF PHOSPHORUS METABOLIC PROCESS 49 1618 1.064e-06 6.781e-05
74 CONNECTIVE TISSUE DEVELOPMENT 14 194 1.198e-06 7.531e-05
75 SKELETAL SYSTEM DEVELOPMENT 22 455 1.223e-06 7.587e-05
76 REGULATION OF MUSCLE SYSTEM PROCESS 14 195 1.273e-06 7.797e-05
77 TELENCEPHALON DEVELOPMENT 15 228 1.598e-06 9.656e-05
78 REGULATION OF CELL SUBSTRATE ADHESION 13 173 1.84e-06 0.0001098
79 CARTILAGE DEVELOPMENT 12 147 1.934e-06 0.0001139
80 NEGATIVE REGULATION OF LOCOMOTION 16 263 2.005e-06 0.0001166
81 CELL SUBSTRATE JUNCTION ASSEMBLY 7 41 2.07e-06 0.0001189
82 NEURON DIFFERENTIATION 32 874 2.217e-06 0.0001253
83 REGULATION OF PROTEIN MODIFICATION PROCESS 50 1710 2.235e-06 0.0001253
84 CELL MOTILITY 31 835 2.429e-06 0.000133
85 LOCALIZATION OF CELL 31 835 2.429e-06 0.000133
86 NEGATIVE REGULATION OF CELL COMMUNICATION 39 1192 2.546e-06 0.0001377
87 CELL PART MORPHOGENESIS 26 633 2.75e-06 0.0001462
88 BEHAVIOR 23 516 2.765e-06 0.0001462
89 REGULATION OF CARTILAGE DEVELOPMENT 8 63 3.905e-06 0.0002042
90 HEMOSTASIS 17 311 4.095e-06 0.0002117
91 REGULATION OF CHONDROCYTE DIFFERENTIATION 7 46 4.626e-06 0.0002366
92 MUSCLE SYSTEM PROCESS 16 282 4.917e-06 0.0002487
93 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 33 957 5.463e-06 0.0002733
94 RESPONSE TO OXYGEN CONTAINING COMPOUND 42 1381 6.304e-06 0.000312
95 TUBE MORPHOGENESIS 17 323 6.764e-06 0.0003313
96 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 41 1360 1.015e-05 0.0004921
97 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 34 1036 1.113e-05 0.0005286
98 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 34 1036 1.113e-05 0.0005286
99 DIVALENT INORGANIC CATION TRANSPORT 15 268 1.145e-05 0.0005382
100 GLIOGENESIS 12 175 1.172e-05 0.0005391
101 REGULATION OF ORGAN GROWTH 8 73 1.193e-05 0.0005391
102 NEURON PROJECTION GUIDANCE 13 205 1.182e-05 0.0005391
103 REGULATION OF DENDRITE DEVELOPMENT 10 120 1.164e-05 0.0005391
104 EXTRACELLULAR STRUCTURE ORGANIZATION 16 304 1.263e-05 0.0005653
105 NEGATIVE REGULATION OF CELL DEATH 30 872 1.566e-05 0.000694
106 NEGATIVE REGULATION OF GENE EXPRESSION 43 1493 1.837e-05 0.0008065
107 TAXIS 20 464 2.029e-05 0.0008823
108 REGULATION OF MUSCLE TISSUE DEVELOPMENT 9 103 2.184e-05 0.0009325
109 RESPONSE TO ABIOTIC STIMULUS 33 1024 2.182e-05 0.0009325
110 REGULATION OF BODY FLUID LEVELS 21 506 2.207e-05 0.0009334
111 REGULATION OF SYSTEM PROCESS 21 507 2.272e-05 0.0009523
112 REGULATION OF EPITHELIAL CELL PROLIFERATION 15 285 2.36e-05 0.000979
113 REGULATION OF GTPASE ACTIVITY 25 673 2.378e-05 0.000979
114 RESPONSE TO HORMONE 30 893 2.451e-05 0.001
115 MUSCLE STRUCTURE DEVELOPMENT 19 432 2.486e-05 0.001004
116 VASCULOGENESIS 7 59 2.504e-05 0.001004
117 CELLULAR RESPONSE TO HORMONE STIMULUS 22 552 2.605e-05 0.001036
118 SECOND MESSENGER MEDIATED SIGNALING 11 160 2.646e-05 0.001043
119 STEM CELL DIFFERENTIATION 12 190 2.667e-05 0.001043
120 REGULATION OF DEVELOPMENTAL GROWTH 15 289 2.774e-05 0.001076
121 OLIGODENDROCYTE DIFFERENTIATION 7 60 2.799e-05 0.001076
122 REGULATION OF HYDROLASE ACTIVITY 39 1327 3.019e-05 0.001151
123 POSITIVE REGULATION OF HYDROLASE ACTIVITY 30 905 3.142e-05 0.001188
124 TISSUE MIGRATION 8 84 3.365e-05 0.001263
125 GLIAL CELL DIFFERENTIATION 10 136 3.466e-05 0.00129
126 HEART PROCESS 8 85 3.667e-05 0.001354
127 REGULATION OF HOMEOSTATIC PROCESS 19 447 3.953e-05 0.001426
128 MORPHOGENESIS OF A BRANCHING STRUCTURE 11 167 3.929e-05 0.001426
129 NEGATIVE REGULATION OF CELL DIFFERENTIATION 23 609 3.938e-05 0.001426
130 PIGMENTATION 8 86 3.992e-05 0.001429
131 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 35 1152 4.107e-05 0.001459
132 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 29 876 4.386e-05 0.001546
133 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 16 337 4.427e-05 0.001549
134 REGULATION OF VASCULATURE DEVELOPMENT 13 233 4.54e-05 0.001577
135 REGULATION OF ION HOMEOSTASIS 12 201 4.63e-05 0.001596
136 TISSUE MORPHOGENESIS 21 533 4.699e-05 0.001608
137 SENSORY ORGAN DEVELOPMENT 20 493 4.764e-05 0.001618
138 POST EMBRYONIC DEVELOPMENT 8 89 5.115e-05 0.001725
139 REGULATION OF CARDIAC MUSCLE CONTRACTION 7 66 5.234e-05 0.001752
140 CELL MIGRATION INVOLVED IN SPROUTING ANGIOGENESIS 4 15 5.569e-05 0.001838
141 REGULATION OF CELL MATRIX ADHESION 8 90 5.543e-05 0.001838
142 SINGLE ORGANISM CELL ADHESION 19 459 5.638e-05 0.001847
143 POSITIVE REGULATION OF LOCOMOTION 18 420 5.68e-05 0.001848
144 POSITIVE REGULATION OF RESPONSE TO STIMULUS 50 1929 5.771e-05 0.001865
145 SYNAPSE ORGANIZATION 10 145 5.984e-05 0.00192
146 REGULATION OF CELL JUNCTION ASSEMBLY 7 68 6.354e-05 0.002025
147 REGULATION OF MUSCLE CONTRACTION 10 147 6.717e-05 0.002126
148 PROTEIN PHOSPHORYLATION 30 944 6.782e-05 0.002132
149 SYSTEM PROCESS 47 1785 6.838e-05 0.002135
150 POSITIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 5 30 7.107e-05 0.002176
151 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 34 1135 7.03e-05 0.002176
152 RESPONSE TO MECHANICAL STIMULUS 12 210 7.068e-05 0.002176
153 TUBE DEVELOPMENT 21 552 7.731e-05 0.002345
154 REGULATION OF CHEMOTAXIS 11 180 7.761e-05 0.002345
155 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 6 49 8.031e-05 0.002411
156 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 41 1492 8.417e-05 0.002511
157 RESPONSE TO GROWTH FACTOR 19 475 8.864e-05 0.002627
158 REGULATION OF ADHERENS JUNCTION ORGANIZATION 6 50 9.015e-05 0.002655
159 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 24 689 9.463e-05 0.002759
160 REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 4 17 9.486e-05 0.002759
161 OSSIFICATION 13 251 9.678e-05 0.002797
162 MORPHOGENESIS OF AN EPITHELIUM 17 400 0.0001009 0.002898
163 RESPONSE TO EXTERNAL STIMULUS 47 1821 0.0001103 0.003147
164 REGULATION OF HEART CONTRACTION 12 221 0.0001149 0.003259
165 RESPONSE TO LIPID 28 888 0.0001363 0.003844
166 REGULATION OF MUSCLE ORGAN DEVELOPMENT 8 103 0.0001442 0.004017
167 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 9 131 0.0001437 0.004017
168 POSITIVE REGULATION OF CELL COMMUNICATION 41 1532 0.0001491 0.004129
169 CELLULAR RESPONSE TO LIPID 18 457 0.0001642 0.004521
170 REGULATION OF STRIATED MUSCLE CONTRACTION 7 79 0.0001655 0.00453
171 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 20 541 0.0001677 0.004536
172 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 20 541 0.0001677 0.004536
173 REGULATION OF EPITHELIAL CELL MIGRATION 10 166 0.0001839 0.004946
174 MELANOCYTE DIFFERENTIATION 4 20 0.0001865 0.004987
175 REGULATION OF SEQUESTERING OF CALCIUM ION 8 107 0.0001879 0.004995
176 REGULATION OF MEMBRANE POTENTIAL 15 343 0.000189 0.004997
177 REGULATION OF GROWTH 22 633 0.0001914 0.005004
178 NEGATIVE REGULATION OF PHOSPHORYLATION 17 422 0.000191 0.005004
179 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 9 138 0.000213 0.005538
180 MUSCLE CELL DIFFERENTIATION 12 237 0.0002204 0.005696
181 REGULATION OF CELL SHAPE 9 139 0.0002249 0.005781
182 REGULATION OF KINASE ACTIVITY 25 776 0.0002269 0.0058
183 RESPONSE TO ORGANIC CYCLIC COMPOUND 28 917 0.0002314 0.005883
184 REGULATION OF ACTIN FILAMENT BASED PROCESS 14 312 0.000237 0.005994
185 RESPONSE TO DRUG 17 431 0.0002446 0.006152
186 MUSCLE ORGAN DEVELOPMENT 13 277 0.0002558 0.006377
187 REGULATION OF PHOSPHOLIPASE C ACTIVITY 5 39 0.0002576 0.006377
188 MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL 5 39 0.0002576 0.006377
189 PLATELET ACTIVATION 9 142 0.0002638 0.006462
190 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 13 278 0.0002649 0.006462
191 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 11 207 0.0002653 0.006462
192 REGULATION OF ORGAN MORPHOGENESIS 12 242 0.0002669 0.006467
193 MEMBRANE DEPOLARIZATION 6 61 0.0002751 0.006631
194 DEVELOPMENTAL PIGMENTATION 5 40 0.0002909 0.006978
195 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 6 62 0.0003008 0.007178
196 NEPHRON DEVELOPMENT 8 115 0.0003081 0.007314
197 POSITIVE REGULATION OF KINASE ACTIVITY 18 482 0.0003135 0.007367
198 REGULATION OF NUCLEOTIDE METABOLIC PROCESS 11 211 0.0003125 0.007367
199 REGULATION OF OSSIFICATION 10 178 0.0003228 0.007547
200 REGULATION OF MUSCLE ADAPTATION 6 63 0.0003284 0.00764
201 REGULATION OF MAPK CASCADE 22 660 0.0003408 0.007889
202 POSITIVE REGULATION OF DENDRITE DEVELOPMENT 6 64 0.0003579 0.008245
203 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 15 365 0.0003667 0.008375
204 REGULATION OF HEART GROWTH 5 42 0.0003672 0.008375
205 EYE DEVELOPMENT 14 326 0.0003696 0.008388
206 COGNITION 12 251 0.0003717 0.008396
207 CIRCULATORY SYSTEM PROCESS 15 366 0.0003774 0.008484
208 BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 4 24 0.0003904 0.008692
209 NEGATIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 4 24 0.0003904 0.008692
210 SOMATIC STEM CELL POPULATION MAINTENANCE 6 66 0.0004232 0.009378
211 REGULATION OF MUSCLE CELL DIFFERENTIATION 9 152 0.0004359 0.009608
212 ANGIOGENESIS 13 293 0.0004378 0.009608
213 ACTIN FILAMENT BASED MOVEMENT 7 93 0.0004541 0.009919
214 PALLIUM DEVELOPMENT 9 153 0.0004572 0.009942
215 POSITIVE REGULATION OF CELL PROLIFERATION 25 814 0.0004615 0.009948
216 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 18 498 0.0004618 0.009948
NumGOOverlapSizeP ValueAdj. P Value
1 REGULATORY REGION NUCLEIC ACID BINDING 37 818 1.412e-09 1.312e-06
2 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 31 629 4.661e-09 2.165e-06
3 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 45 1199 7.129e-09 2.208e-06
4 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 20 315 5.159e-08 1.198e-05
5 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 20 328 9.998e-08 1.858e-05
6 SEQUENCE SPECIFIC DNA BINDING 38 1037 2.224e-07 3.443e-05
7 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 12 133 6.647e-07 8.822e-05
8 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 15 226 1.431e-06 0.0001583
9 MACROMOLECULAR COMPLEX BINDING 44 1399 1.534e-06 0.0001583
10 ACTIVATING TRANSCRIPTION FACTOR BINDING 8 57 1.799e-06 0.0001671
11 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 24 588 7.488e-06 0.0006324
12 MOLECULAR FUNCTION REGULATOR 40 1353 2.065e-05 0.001599
13 CYTOSKELETAL PROTEIN BINDING 28 819 3.405e-05 0.002433
14 CORE PROMOTER PROXIMAL REGION DNA BINDING 17 371 4.003e-05 0.002656
15 METAL ION TRANSMEMBRANE TRANSPORTER ACTIVITY 18 417 5.18e-05 0.003208
16 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC BINDING 8 90 5.543e-05 0.003219
17 DOUBLE STRANDED DNA BINDING 26 764 7.061e-05 0.003859
18 ACTIN BINDING 17 393 8.145e-05 0.004204
19 TRANSCRIPTION FACTOR BINDING 20 524 0.0001096 0.005358
20 TRANSCRIPTION COACTIVATOR ACTIVITY 14 296 0.0001376 0.006391
21 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 12 228 0.0001539 0.006809
22 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 14 303 0.0001754 0.007408
23 DIVALENT INORGANIC CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 10 167 0.0001931 0.0078
24 PROTEIN KINASE ACTIVITY 22 640 0.0002231 0.008637
NumGOOverlapSizeP ValueAdj. P Value
1 CELL PROJECTION 60 1786 1.053e-09 6.151e-07
2 NEURON PART 47 1265 4.311e-09 1.135e-06
3 NEURON PROJECTION 39 942 5.829e-09 1.135e-06
4 CELL JUNCTION 42 1151 5.329e-08 7.78e-06
5 MEMBRANE REGION 41 1134 1.005e-07 1.174e-05
6 SOMATODENDRITIC COMPARTMENT 29 650 1.288e-07 1.253e-05
7 CELL BODY 23 494 1.328e-06 0.0001108
8 DENDRITE 21 451 3.872e-06 0.0002826
9 MEMBRANE MICRODOMAIN 16 288 6.421e-06 0.0004167
10 SYNAPSE 28 754 7.631e-06 0.0004457
11 ACTIN CYTOSKELETON 19 444 3.61e-05 0.001916
12 CELL LEADING EDGE 16 350 6.93e-05 0.003373
13 CELL SUBSTRATE JUNCTION 17 398 9.496e-05 0.004266
14 RUFFLE 10 156 0.0001104 0.004604
15 PLASMA MEMBRANE PROTEIN COMPLEX 19 510 0.000221 0.008606

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04540_Gap_junction 10 90 8.46e-07 0.0001523
2 hsa04151_PI3K_AKT_signaling_pathway 18 351 5.191e-06 0.0004081
3 hsa04270_Vascular_smooth_muscle_contraction 10 116 8.614e-06 0.0004081
4 hsa04510_Focal_adhesion 13 200 9.068e-06 0.0004081
5 hsa04971_Gastric_acid_secretion 8 74 1.321e-05 0.0004756
6 hsa04720_Long.term_potentiation 7 70 7.662e-05 0.002299
7 hsa04912_GnRH_signaling_pathway 8 101 0.0001257 0.003232
8 hsa04970_Salivary_secretion 7 89 0.0003472 0.007811
9 hsa04010_MAPK_signaling_pathway 12 268 0.0006658 0.01306
10 hsa04916_Melanogenesis 7 101 0.000746 0.01306
11 hsa04014_Ras_signaling_pathway 11 236 0.0007979 0.01306
12 hsa04512_ECM.receptor_interaction 6 85 0.001614 0.02421
13 hsa04012_ErbB_signaling_pathway 6 87 0.001819 0.02518
14 hsa04730_Long.term_depression 5 70 0.003738 0.04806
15 hsa04020_Calcium_signaling_pathway 8 177 0.004858 0.05829
16 hsa00534_Glycosaminoglycan_biosynthesis_._heparan_sulfate 3 26 0.006425 0.07228
17 hsa04390_Hippo_signaling_pathway 7 154 0.007983 0.08452
18 hsa04666_Fc_gamma_R.mediated_phagocytosis 5 95 0.01331 0.1331
19 hsa04810_Regulation_of_actin_cytoskeleton 8 214 0.01438 0.1363
20 hsa04972_Pancreatic_secretion 5 101 0.01696 0.1526
21 hsa04520_Adherens_junction 4 73 0.02281 0.1955
22 hsa04310_Wnt_signaling_pathway 6 151 0.02472 0.2022
23 hsa04962_Vasopressin.regulated_water_reabsorption 3 44 0.02697 0.2024
24 hsa04114_Oocyte_meiosis 5 114 0.02699 0.2024
25 hsa04070_Phosphatidylinositol_signaling_system 4 78 0.02825 0.2034
26 hsa04380_Osteoclast_differentiation 5 128 0.04132 0.2861
27 hsa04514_Cell_adhesion_molecules_.CAMs. 5 136 0.05124 0.3416
28 hsa04910_Insulin_signaling_pathway 5 138 0.05392 0.3466
29 hsa04630_Jak.STAT_signaling_pathway 5 155 0.0799 0.4959
30 hsa04370_VEGF_signaling_pathway 3 76 0.1022 0.6129
31 hsa04664_Fc_epsilon_RI_signaling_pathway 3 79 0.1114 0.6468
32 hsa04722_Neurotrophin_signaling_pathway 4 127 0.1187 0.6679
33 hsa04360_Axon_guidance 4 130 0.1263 0.6738
34 hsa04960_Aldosterone.regulated_sodium_reabsorption 2 42 0.1273 0.6738
35 hsa04530_Tight_junction 4 133 0.134 0.6873
36 hsa04914_Progesterone.mediated_oocyte_maturation 3 87 0.1375 0.6873
37 hsa04210_Apoptosis 3 89 0.1443 0.7019
38 hsa04150_mTOR_signaling_pathway 2 52 0.1787 0.8246
39 hsa04340_Hedgehog_signaling_pathway 2 56 0.2 0.8372
40 hsa04660_T_cell_receptor_signaling_pathway 3 108 0.2137 0.8704
41 hsa00230_Purine_metabolism 4 162 0.2176 0.8704
42 hsa04670_Leukocyte_transendothelial_migration 3 117 0.2488 0.9736
43 hsa04920_Adipocytokine_signaling_pathway 2 68 0.2653 1
44 hsa04976_Bile_secretion 2 71 0.2818 1
45 hsa04662_B_cell_receptor_signaling_pathway 2 75 0.3036 1
46 hsa04062_Chemokine_signaling_pathway 4 189 0.3047 1
47 hsa04260_Cardiac_muscle_contraction 2 77 0.3145 1
48 hsa04650_Natural_killer_cell_mediated_cytotoxicity 3 136 0.3249 1
49 hsa04145_Phagosome 3 156 0.4051 1
50 hsa04142_Lysosome 2 121 0.5351 1
51 hsa04144_Endocytosis 3 203 0.5783 1
52 hsa04141_Protein_processing_in_endoplasmic_reticulum 2 168 0.7117 1
53 hsa04740_Olfactory_transduction 2 388 0.9795 1

Quest ID: 6a4035f2b7d4a34b1d905914469700c5