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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-let-7a-5p CSNK2A1 -0 0.87866 -0.22 0.00389 miRNAWalker2 validate; TargetScan -1.57 0.03834
2 hsa-miR-100-5p CREBBP 0.28 0.00109 -0.01 0.90826 miRNAWalker2 validate -0.32 0.03648
3 hsa-miR-100-5p CUL1 0.28 0.00109 -0.07 0.58078 miRNAWalker2 validate -0.36 0.03007
4 hsa-miR-125a-5p TP53 -0.05 0.04217 0.31 0.03969 miRNAWalker2 validate; miRTarBase; miRanda -2.67 0.00829 23079745 Furthermore treatment of HCC cells with 5-aza-2'-deoxycytidine or ectopic expression of wildtype but not mutated p53 restored miR-125a-5p and miR-125b expression and inhibited tumor cell growth suggesting their regulation by promoter methylation and p53 activity
5 hsa-miR-126-5p MMP7 -0.17 0.16126 -0.78 0.00557 miRNAWalker2 validate -0.65 0.02466
6 hsa-miR-140-3p MAPK8 0.22 0 -0.21 0.05783 miRNAWalker2 validate -0.95 0.00894
7 hsa-miR-148a-3p APC 0.14 0.34475 0.01 0.92018 miRNAWalker2 validate -0.12 0.01955
8 hsa-miR-155-5p CCND1 0.21 0.01528 -0.38 0.05738 miRNAWalker2 validate -0.99 0.00027
9 hsa-miR-155-5p JUN 0.21 0.01528 -0.29 0.1332 miRNAWalker2 validate; miRTarBase -0.61 0.02374 26055960; 26055960; 23693020; 23693020 We found in FLT3-mutated AML a significant down-regulation of miR-155 target genes CEBPB and SPI1 and up-regulation of miR-155 regulator genes JUN and RUNX1;Our results suggest that activating mutation of FLT3 in AML can lead through the induction of JUN to an increased expression of miR-155 which then causes down-regulation of SPI1 and CEBPB and consequently may causes block of myeloid differentiation;In the present study we demonstrated for the first time that activation of RAGE by S100P regulates oncogenic microRNA-155 miR-155 expression through Activator Protein-1 AP-1 stimulation in colon cancer cells;Attenuation of AP-1 activation through pharmacological inhibition of MEK activation or genetic inhibition of c-Jun activation using dominant negative c-Jun TAM67 suppressed miR-155 induction by exogenous S100P
10 hsa-miR-155-5p VANGL1 0.21 0.01528 -0.34 0.00025 miRNAWalker2 validate -0.42 0.00121
11 hsa-miR-155-5p WNT5A 0.21 0.01528 -0.28 0.06403 miRNAWalker2 validate; mirMAP -0.52 0.01461
12 hsa-miR-15a-5p CCND1 0.08 0.08019 -0.38 0.05738 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -1.11 0.04279 23867991; 18931683; 18931683 miR-15a and miR-16-1 are important tumor suppressors through modulating B cell lymphoma 2 Bcl-2 Cyclin D1 D2 and others;Here we report that the miR-15a and miR-16-1 cluster targets CCND1 encoding cyclin D1 and WNT3A which promotes several tumorigenic features such as survival proliferation and invasion;In cancer cells of advanced prostate tumors the miR-15a and miR-16 level is significantly decreased whereas the expression of BCL2 CCND1 and WNT3A is inversely upregulated
13 hsa-miR-16-5p CCND1 0.06 0.00803 -0.38 0.05738 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -4.98 0.00068
14 hsa-miR-16-5p WNT5A 0.06 0.00803 -0.28 0.06403 miRNAWalker2 validate -4.12 0.00019
15 hsa-miR-185-5p RHOA -0.08 0.00466 0.35 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.84 0.0496
16 hsa-miR-192-5p APC 0.26 0.07179 0.01 0.92018 miRNAWalker2 validate -0.12 0.02208
17 hsa-miR-192-5p FZD1 0.26 0.07179 -0.15 0.01283 miRNAWalker2 validate -0.14 0.00495
18 hsa-miR-193b-3p LEF1 -0.19 0.00049 0.7 0.00044 miRNAWalker2 validate -1.48 0.00082
19 hsa-miR-194-5p RAC1 0.24 0.07016 -0.22 0.01856 miRNAWalker2 validate; miRTarBase; miRNATAP -0.17 0.04604
20 hsa-miR-195-5p CCND1 0.28 1.0E-5 -0.38 0.05738 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.83 0.02718 21350001; 19441017 Raf-1 and Ccnd1 were identified as novel direct targets of miR-195 and miR-497 miR-195/497 expression levels in clinical specimens were found to be correlated inversely with malignancy of breast cancer;Silencing of cyclin D1 CDK6 or E2F3 phenocopied the effect of miR-195 whereas overexpression of these proteins attenuated miR-195-induced G1 arrest
21 hsa-miR-200c-3p RHOA -0.1 0.00014 0.35 1.0E-5 miRNAWalker2 validate; MirTarget; miRNATAP -0.98 0.01319
22 hsa-miR-215-5p FZD1 0.12 0.28158 -0.15 0.01283 miRNAWalker2 validate -0.15 0.02228
23 hsa-miR-221-3p DKK2 -0.09 0.00027 0.37 0.00031 miRNAWalker2 validate; miRTarBase -1.42 0.0164
24 hsa-miR-221-3p RHOA -0.09 0.00027 0.35 1.0E-5 miRNAWalker2 validate -1.01 0.02789
25 hsa-miR-25-3p DKK4 -0.06 0.17602 0.13 0.10965 miRNAWalker2 validate -0.77 0.0002
26 hsa-miR-26a-5p GSK3B 0.11 0 -0.55 0.00027 miRNAWalker2 validate; miRNATAP -3.77 0.00018
27 hsa-miR-26a-5p LRP6 0.11 0 -0.61 0.00016 miRNAWalker2 validate -3.59 0.00113
28 hsa-miR-26a-5p MYC 0.11 0 -0.39 0.00215 miRNAWalker2 validate -3.59 1.0E-5
29 hsa-miR-26b-5p RUVBL1 0.32 0.00241 -0.36 7.0E-5 miRNAWalker2 validate -0.21 0.04479
30 hsa-miR-27a-3p APC -0.07 0.01321 0.01 0.92018 miRNAWalker2 validate; miRTarBase; miRNATAP -0.87 0.0069
31 hsa-miR-27a-3p TP53 -0.07 0.01321 0.31 0.03969 miRNAWalker2 validate -2.64 0.0004
32 hsa-miR-27b-3p CUL1 0.02 0.49367 -0.07 0.58078 miRNAWalker2 validate -1.09 0.01997
33 hsa-miR-27b-3p MAPK9 0.02 0.49367 -0.01 0.9309 miRNAWalker2 validate -0.7 0.01219
34 hsa-miR-29a-3p SFRP2 0.19 0 -0.8 0.0032 miRNAWalker2 validate; miRTarBase -2.41 0.00301
35 hsa-miR-29c-3p WNT4 0.81 0 -0.14 0.28902 miRNAWalker2 validate; miRTarBase -0.25 0.01033
36 hsa-miR-30a-5p WNT5A 0.25 0.00897 -0.28 0.06403 miRNAWalker2 validate; mirMAP -0.46 0.01732
37 hsa-miR-30c-5p PLCB1 0.06 0.05097 -0.39 0.00049 miRNAWalker2 validate -1.01 0.04033
38 hsa-miR-31-3p RHOA -0.48 0.00142 0.35 1.0E-5 miRNAWalker2 validate; miRTarBase -0.14 0.02962 22289355 miR-31 exerts its metastasis-suppressor activity by targeting a cohort of pro-metastatic genes including RhoA and WAVE3
39 hsa-miR-324-3p CSNK1A1 0.09 0.11052 -0.41 0.01132 miRNAWalker2 validate -0.78 0.02073
40 hsa-miR-324-5p CCND3 -0.09 0.00811 0.4 0 miRNAWalker2 validate -0.83 0.00753
41 hsa-miR-335-5p FZD10 0.02 0.83798 0.01 0.91052 miRNAWalker2 validate -0.28 0.02111
42 hsa-miR-335-5p PPP2R5A 0.02 0.83798 0.08 0.52412 miRNAWalker2 validate -0.41 0.01877
43 hsa-miR-335-5p SMAD3 0.02 0.83798 -0.13 0.21226 miRNAWalker2 validate -0.32 0.03136
44 hsa-miR-342-3p JUN 0.2 0 -0.29 0.1332 miRNAWalker2 validate -1.66 0.00536
45 hsa-miR-34a-5p AXIN2 -0.07 0.02515 0.01 0.77682 miRNAWalker2 validate; miRTarBase -0.41 0.03009 23624843; 23624843 Suppression of Axin2 by p53 or miR-34 increases nuclear GSK-3β abundance and leads to decreased Snail expression in colorectal cancer cells;Conversely expression of the non-coding UTR of Axin2 causes depletion of endogenous miR-34 via the miR-sponge effect together with increased Axin2 function supporting that the RNA-RNA interactions with Axin2 transcripts act as an endogenous decoy for miR-34
46 hsa-miR-608 TP53 0.05 0.56051 0.31 0.03969 miRNAWalker2 validate -0.44 0.04541
47 hsa-miR-615-3p CCND3 -0.38 0.00163 0.4 0 miRNAWalker2 validate -0.15 0.04764
48 hsa-miR-877-3p GSK3B -0.06 0.6129 -0.55 0.00027 miRNAWalker2 validate -0.37 0.02939
49 hsa-miR-93-5p PRKACB -0.09 0.00043 0.84 0 miRNAWalker2 validate -2.24 0.04378
50 hsa-miR-98-5p WNT10B -0.04 0.57599 0.13 0.09017 miRNAWalker2 validate -0.28 0.03087
51 hsa-miR-15b-5p AXIN2 -0.05 0.09577 0.01 0.77682 miRTarBase; MirTarget; miRNATAP -0.42 0.03666
52 hsa-miR-23b-3p PRKACB 0.01 0.54816 0.84 0 miRTarBase -3.59 0.03048
53 hsa-let-7b-3p CTNNB1 -0 0.99435 -0.22 0.07306 MirTarget; miRNATAP -0.36 0.01795
54 hsa-let-7b-3p PPP3CA -0 0.99435 -0.17 0.17383 MirTarget; miRNATAP -0.36 0.02091
55 hsa-let-7d-3p PRKACB -0.21 0.03526 0.84 0 MirTarget -0.5 0.02948
56 hsa-let-7d-5p FZD4 -0.04 0.04833 0.25 0.00096 MirTarget; miRNATAP -2.2 0.00424
57 hsa-let-7f-2-3p EP300 -0.08 0.38923 0.01 0.96819 MirTarget -0.35 0.03758
58 hsa-let-7f-2-3p CREBBP -0.08 0.38923 -0.01 0.90826 MirTarget -0.31 0.03738
59 hsa-let-7f-2-3p PPP2R5E -0.08 0.38923 -0.15 0.07345 MirTarget -0.23 0.03942
60 hsa-let-7f-2-3p NLK -0.08 0.38923 0.1 0.4652 MirTarget -0.43 0.01437
61 hsa-let-7f-5p FZD4 -0.03 0.57164 0.25 0.00096 MirTarget; miRNATAP -0.47 0.00267
62 hsa-let-7g-3p TCF7L2 0.26 0.03051 -0.26 0.00329 MirTarget; miRNATAP -0.31 0.00045
63 hsa-miR-100-5p FZD5 0.28 0.00109 -0.14 0.18851 MirTarget; miRNATAP -0.33 0.0217
64 hsa-miR-1184 PSEN1 -0.03 0.55358 -0.12 0.34246 MirTarget; miRNATAP -0.71 0.02323
65 hsa-miR-1207-5p CAMK2A -0.04 0.28386 0.03 0.77855 MirTarget; miRNATAP -0.93 0.00921
66 hsa-miR-1228-3p PRKACB 0.02 0.71539 0.84 0 MirTarget -0.77 0.04717
67 hsa-miR-1228-3p SMAD2 0.02 0.71539 -0.16 0.13545 MirTarget -0.54 0.01224
68 hsa-miR-1231 FZD4 -0.05 0.34854 0.25 0.00096 MirTarget; miRNATAP -0.43 0.01024
69 hsa-miR-1246 AXIN2 -0.32 0.01352 0.01 0.77682 MirTarget; PITA; miRNATAP -0.09 0.03378
70 hsa-miR-1252-5p SMAD4 0.08 0.36972 -0 0.99519 MirTarget -0.41 0.02801
71 hsa-miR-125a-5p PPP2R5C -0.05 0.04217 0.29 4.0E-5 MirTarget; PITA; miRanda -1.49 0.00174
72 hsa-miR-125b-5p CSNK2A1 0.13 2.0E-5 -0.22 0.00389 MirTarget; miRNATAP -0.95 0.00193
73 hsa-miR-1275 DVL3 0.22 0.00022 -0.49 0 MirTarget -0.44 0.03216
74 hsa-miR-1275 FZD1 0.22 0.00022 -0.15 0.01283 MirTarget -0.32 0.00755
75 hsa-miR-1275 FOSL1 0.22 0.00022 -0.38 0.00166 MirTarget -0.61 0.01231
76 hsa-miR-1283 PPP2R5E 0.02 0.85754 -0.15 0.07345 MirTarget; PITA; miRNATAP -0.24 0.0255
77 hsa-miR-1283 NFATC3 0.02 0.85754 0.42 0.00212 MirTarget; miRNATAP -0.41 0.02902
78 hsa-miR-1294 TP53 -0.15 0.19055 0.31 0.03969 MirTarget -0.35 0.03369
79 hsa-miR-1299 NFAT5 0.22 0.08255 -0.09 0.53721 MirTarget; mirMAP; miRNATAP -0.5 0.00021
80 hsa-miR-1299 NFATC3 0.22 0.08255 0.42 0.00212 MirTarget; miRNATAP -0.32 0.01898
81 hsa-miR-1301-3p SFRP1 -0.34 0.0071 0.08 0.58789 MirTarget -0.3 0.03046
82 hsa-miR-133b TBL1XR1 0.29 0.15825 -0.39 0.0325 MirTarget; PITA; miRanda -0.24 0.02686
83 hsa-miR-140-3p WNT5A 0.22 0 -0.28 0.06403 MirTarget; miRNATAP -1.79 0.00027
84 hsa-miR-140-5p FZD6 0.38 0.00137 -1.23 0 MirTarget; miRanda -0.58 0.00734
85 hsa-miR-143-3p CSNK2A1 0.13 0.00061 -0.22 0.00389 MirTarget -0.58 0.02209
86 hsa-miR-143-3p MAP3K7 0.13 0.00061 -0.25 0.03111 MirTarget; miRNATAP -1.21 0.002
87 hsa-miR-144-3p PRKX 0.11 0.22621 0.02 0.89159 MirTarget -0.47 0.04395
88 hsa-miR-145-5p SENP2 0.15 1.0E-5 -0.45 0.0014 MirTarget -1.08 0.04672
89 hsa-miR-146a-5p FZD1 0.22 0.02592 -0.15 0.01283 MirTarget -0.25 0.00042
90 hsa-miR-146a-5p WNT3 0.22 0.02592 -0.12 0.33627 MirTarget -0.44 0.00394
91 hsa-miR-150-5p DVL3 0.61 0 -0.49 0 MirTarget -0.32 0.00041
92 hsa-miR-152-3p WNT10B -0.25 0.00117 0.13 0.09017 MirTarget -0.24 0.03416
93 hsa-miR-154-5p PPP2R1B -0.16 0.13893 -0.01 0.94508 MirTarget -0.36 0.0034
94 hsa-miR-154-5p CAMK2G -0.16 0.13893 0.09 0.22741 MirTarget; miRNATAP -0.17 0.03428
95 hsa-miR-15a-5p SMAD3 0.08 0.08019 -0.13 0.21226 MirTarget -0.72 0.01049
96 hsa-miR-15a-5p NFAT5 0.08 0.08019 -0.09 0.53721 MirTarget -0.77 0.04835
97 hsa-miR-16-1-3p PRKX -0.03 0.81009 0.02 0.89159 MirTarget -0.53 0.00265
98 hsa-miR-182-5p PRKACB -0.36 0 0.84 0 MirTarget; miRNATAP -1.83 0
99 hsa-miR-1825 NLK 0.05 0.35622 0.1 0.4652 MirTarget; PITA; miRNATAP -0.56 0.04895
100 hsa-miR-183-5p PRKACB -0.81 0 0.84 0 MirTarget -0.4 0.00305
101 hsa-miR-183-5p PPP2R5C -0.81 0 0.29 4.0E-5 MirTarget; miRNATAP -0.14 0.00663
102 hsa-miR-185-3p PPP2R5B 0.32 0.03354 -0.19 0.0051 MirTarget -0.11 0.04072
103 hsa-miR-185-3p FOSL1 0.32 0.03354 -0.38 0.00166 MirTarget -0.23 0.01498
104 hsa-miR-185-3p PPARD 0.32 0.03354 -0.26 0.01336 MirTarget -0.33 4.0E-5
105 hsa-miR-185-5p NFATC3 -0.08 0.00466 0.42 0.00212 MirTarget; miRNATAP -1.98 0.00651
106 hsa-miR-190b ROCK1 -0.03 0.6766 0.07 0.68592 MirTarget; PITA; miRanda -0.52 0.03231
107 hsa-miR-193b-5p NFATC2 -0.24 5.0E-5 0.62 0 MirTarget -0.66 0.01443
108 hsa-miR-195-3p WNT5A 0.32 0.0647 -0.28 0.06403 MirTarget; mirMAP; miRNATAP -0.22 0.04173
109 hsa-miR-195-3p PRKX 0.32 0.0647 0.02 0.89159 MirTarget; mirMAP -0.52 0
110 hsa-miR-195-5p SMAD3 0.28 1.0E-5 -0.13 0.21226 MirTarget -0.65 0.0006
111 hsa-miR-195-5p NFAT5 0.28 1.0E-5 -0.09 0.53721 MirTarget -0.58 0.0311
112 hsa-miR-196a-3p PPP2R5C -0.16 0.07845 0.29 4.0E-5 MirTarget -0.25 0.0073
113 hsa-miR-198 FBXW11 0 0.89942 0.05 0.46669 MirTarget; PITA -0.89 0.00045
114 hsa-miR-198 DAAM1 0 0.89942 0.06 0.65941 MirTarget -1.23 0.03098
115 hsa-miR-198 BTRC 0 0.89942 0.05 0.57743 MirTarget -0.66 0.03485
116 hsa-miR-19b-2-5p SFRP1 0.03 0.74975 0.08 0.58789 MirTarget -0.66 0.00133
117 hsa-miR-19b-3p FZD6 0.07 0.0115 -1.23 0 MirTarget -2.68 0.01315
118 hsa-miR-200b-3p PRKCB -0.29 0.02427 1.15 0 MirTarget -0.48 0.01198
119 hsa-miR-200b-3p WNT16 -0.29 0.02427 0.08 0.4325 MirTarget -0.26 0.00639
120 hsa-miR-200c-3p PRKACB -0.1 0.00014 0.84 0 MirTarget; miRNATAP -3.39 0.00013
121 hsa-miR-200c-3p PRKCB -0.1 0.00014 1.15 0 MirTarget; miRNATAP -5.18 0
122 hsa-miR-204-5p FBXW11 -0.01 0.92374 0.05 0.46669 MirTarget -0.19 0.00695
123 hsa-miR-20b-5p CHP2 0.11 0.13034 -0.02 0.82462 MirTarget -0.45 0.00163
124 hsa-miR-221-3p NFATC2 -0.09 0.00027 0.62 0 MirTarget -2.34 0.00219
125 hsa-miR-222-3p SKP1 -0.03 0.15714 0.21 0.09686 MirTarget -1.96 0.02948
126 hsa-miR-23b-3p PPP2R5E 0.01 0.54816 -0.15 0.07345 MirTarget -1.88 0.00817
127 hsa-miR-24-3p NFATC2 -0.03 0.05009 0.62 0 MirTarget -4.77 0.00421
128 hsa-miR-25-3p CAMK2A -0.06 0.17602 0.03 0.77855 MirTarget -0.87 0.00157
129 hsa-miR-26a-5p VANGL2 0.11 0 -0.37 3.0E-5 MirTarget -2.77 0
130 hsa-miR-27a-3p SMAD4 -0.07 0.01321 -0 0.99519 MirTarget -1.7 0.00811
131 hsa-miR-27a-3p PRKCB -0.07 0.01321 1.15 0 MirTarget; miRNATAP -4.04 6.0E-5
132 hsa-miR-27a-3p NFAT5 -0.07 0.01321 -0.09 0.53721 MirTarget -1.7 0.0207
133 hsa-miR-27a-3p PRKX -0.07 0.01321 0.02 0.89159 MirTarget; miRNATAP -3.17 0.00014
134 hsa-miR-27b-3p NFAT5 0.02 0.49367 -0.09 0.53721 MirTarget -1.22 0.02974
135 hsa-miR-28-5p CTNNBIP1 -0.03 0.63053 -0.06 0.38486 MirTarget; miRanda -0.42 0.01272
136 hsa-miR-29a-3p NFAT5 0.19 0 -0.09 0.53721 MirTarget; miRNATAP -1.29 0.00225
137 hsa-miR-29b-2-5p DVL3 0.15 0.02891 -0.49 0 MirTarget -0.37 0.03519
138 hsa-miR-29b-3p NFAT5 0.43 0.00645 -0.09 0.53721 MirTarget; miRNATAP -0.26 0.01605
139 hsa-miR-29c-3p CTNNBIP1 0.81 0 -0.06 0.38486 MirTarget; miRNATAP -0.14 0.01387
140 hsa-miR-31-3p NFATC3 -0.48 0.00142 0.42 0.00212 MirTarget -0.26 0.01646
141 hsa-miR-320d PRKCG -0.07 0.00582 0.16 0.07555 MirTarget; miRanda -1.26 0.00742
142 hsa-miR-329-3p NLK -0.17 0.05087 0.1 0.4652 MirTarget -0.42 0.01834
143 hsa-miR-331-3p CAMK2A -0.1 0.14768 0.03 0.77855 MirTarget -0.5 0.00556
144 hsa-miR-335-5p ROCK1 0.02 0.83798 0.07 0.68592 MirTarget -0.58 0.01039
145 hsa-miR-339-5p BTRC -0.08 0.38587 0.05 0.57743 MirTarget; miRanda -0.25 0.01922
146 hsa-miR-342-3p CTBP2 0.2 0 -0.09 0.04263 MirTarget; PITA; miRanda; miRNATAP -0.54 1.0E-5
147 hsa-miR-367-3p TBL1XR1 0.17 0.12565 -0.39 0.0325 MirTarget -0.44 0.02566
148 hsa-miR-374a-3p PRICKLE2 0.03 0.76297 -0.1 0.26684 MirTarget; miRNATAP -0.21 0.04408
149 hsa-miR-374b-3p PPP3CA -0.15 0.21083 -0.17 0.17383 MirTarget -0.25 0.04609
150 hsa-miR-376c-3p PPP2R5A -0.19 0.15105 0.08 0.52412 MirTarget -0.24 0.03069

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 WNT SIGNALING PATHWAY 77 351 1.039e-106 4.836e-103
2 CANONICAL WNT SIGNALING PATHWAY 41 95 5.799e-68 1.349e-64
3 NON CANONICAL WNT SIGNALING PATHWAY 35 140 7.759e-48 1.203e-44
4 REGULATION OF WNT SIGNALING PATHWAY 43 310 3.185e-47 3.705e-44
5 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 51 1021 5.446e-34 5.068e-31
6 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 30 197 6.817e-34 5.286e-31
7 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 31 236 5.932e-33 3.943e-30
8 POSITIVE REGULATION OF RESPONSE TO STIMULUS 62 1929 2.672e-31 1.554e-28
9 REGULATION OF ORGAN MORPHOGENESIS 30 242 4.2e-31 2.172e-28
10 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 58 1672 1.146e-30 5.333e-28
11 WNT SIGNALING PATHWAY CALCIUM MODULATING PATHWAY 18 39 1.768e-30 7.478e-28
12 REGULATION OF PROTEIN MODIFICATION PROCESS 58 1710 3.796e-30 1.472e-27
13 TISSUE MORPHOGENESIS 37 533 3.667e-29 1.219e-26
14 BETA CATENIN DESTRUCTION COMPLEX DISASSEMBLY 15 22 3.568e-29 1.219e-26
15 POSITIVE REGULATION OF GENE EXPRESSION 57 1733 7.631e-29 2.367e-26
16 EPITHELIUM DEVELOPMENT 45 945 9.362e-29 2.563e-26
17 TISSUE DEVELOPMENT 54 1518 9.013e-29 2.563e-26
18 TUBE MORPHOGENESIS 31 323 1.203e-28 3.11e-26
19 MORPHOGENESIS OF AN EPITHELIUM 33 400 2.335e-28 5.718e-26
20 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 53 1492 3.905e-28 9.086e-26
21 POSITIVE REGULATION OF CELL COMMUNICATION 53 1532 1.408e-27 3.121e-25
22 ORGAN MORPHOGENESIS 42 841 1.598e-27 3.381e-25
23 REGULATION OF ESTABLISHMENT OF PLANAR POLARITY 21 110 5.135e-26 1.039e-23
24 REGULATION OF PHOSPHORUS METABOLIC PROCESS 52 1618 1.767e-25 3.426e-23
25 EMBRYO DEVELOPMENT 41 894 2.104e-25 3.915e-23
26 EMBRYONIC MORPHOGENESIS 34 539 2.305e-25 4.125e-23
27 PATTERN SPECIFICATION PROCESS 31 418 3.302e-25 5.69e-23
28 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 54 1805 4.328e-25 7.193e-23
29 TUBE DEVELOPMENT 34 552 5.025e-25 8.062e-23
30 POSITIVE REGULATION OF MOLECULAR FUNCTION 53 1791 2.474e-24 3.837e-22
31 REGULATION OF CELL DIFFERENTIATION 49 1492 3.024e-24 4.538e-22
32 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 33 554 8.143e-24 1.184e-21
33 NEGATIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 22 162 8.725e-24 1.22e-21
34 REGIONALIZATION 27 311 8.914e-24 1.22e-21
35 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 43 1135 1.997e-23 2.654e-21
36 CELL FATE COMMITMENT 24 227 3.143e-23 4.062e-21
37 NEGATIVE REGULATION OF CELL COMMUNICATION 42 1192 1.208e-21 1.519e-19
38 REGULATION OF CELL CYCLE 38 949 2.183e-21 2.605e-19
39 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 41 1142 2.133e-21 2.605e-19
40 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 44 1360 2.737e-21 3.184e-19
41 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 38 957 2.922e-21 3.316e-19
42 CARDIOVASCULAR SYSTEM DEVELOPMENT 35 788 4.323e-21 4.678e-19
43 CIRCULATORY SYSTEM DEVELOPMENT 35 788 4.323e-21 4.678e-19
44 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 49 1784 7.168e-21 7.58e-19
45 REGULATION OF EMBRYONIC DEVELOPMENT 18 114 7.862e-21 8.129e-19
46 NEUROGENESIS 44 1402 8.999e-21 9.102e-19
47 ANTERIOR POSTERIOR PATTERN SPECIFICATION 21 194 1.282e-20 1.243e-18
48 NEURON DIFFERENTIATION 36 874 1.262e-20 1.243e-18
49 POSITIVE REGULATION OF CELL DIFFERENTIATION 35 823 1.756e-20 1.668e-18
50 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 38 1036 4.508e-20 4.113e-18
51 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 38 1036 4.508e-20 4.113e-18
52 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 25 365 1.604e-19 1.436e-17
53 CELL PROLIFERATION 31 672 4.046e-19 3.552e-17
54 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 42 1395 4.31e-19 3.714e-17
55 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 47 1848 1.431e-18 1.211e-16
56 HEART DEVELOPMENT 26 466 4.497e-18 3.736e-16
57 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 17 134 4.782e-18 3.904e-16
58 INTRACELLULAR SIGNAL TRANSDUCTION 43 1572 5.099e-18 4.09e-16
59 REGULATION OF CELL PROLIFERATION 42 1496 5.574e-18 4.396e-16
60 DORSAL VENTRAL AXIS SPECIFICATION 10 20 7.893e-18 6.121e-16
61 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 35 1004 9.57e-18 7.3e-16
62 REGULATION OF CELL DEATH 41 1472 2.106e-17 1.581e-15
63 REGULATION OF BINDING 21 283 3.329e-17 2.459e-15
64 CELL DEVELOPMENT 40 1426 4.637e-17 3.371e-15
65 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 31 801 5.862e-17 4.196e-15
66 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 36 1152 9.377e-17 6.573e-15
67 CELLULAR RESPONSE TO RETINOIC ACID 13 65 9.465e-17 6.573e-15
68 RESPONSE TO RETINOIC ACID 15 107 1.032e-16 7.062e-15
69 SENSORY ORGAN DEVELOPMENT 25 493 2.013e-16 1.357e-14
70 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 42 1656 2.16e-16 1.435e-14
71 AXIS SPECIFICATION 14 90 2.498e-16 1.637e-14
72 REGULATION OF CELLULAR PROTEIN LOCALIZATION 26 552 2.749e-16 1.776e-14
73 EMBRYONIC ORGAN DEVELOPMENT 23 406 3.417e-16 2.178e-14
74 POSITIVE REGULATION OF CATALYTIC ACTIVITY 40 1518 3.957e-16 2.488e-14
75 EPITHELIAL TO MESENCHYMAL TRANSITION 12 56 6.14e-16 3.809e-14
76 NEURAL TUBE DEVELOPMENT 16 149 7.265e-16 4.432e-14
77 PROTEIN PHOSPHORYLATION 32 944 7.334e-16 4.432e-14
78 REGULATION OF CELLULAR RESPONSE TO STRESS 28 691 7.738e-16 4.616e-14
79 REGULATION OF RESPONSE TO STRESS 39 1468 7.985e-16 4.703e-14
80 POSITIVE REGULATION OF WNT SIGNALING PATHWAY 16 152 1.002e-15 5.825e-14
81 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 21 337 1.136e-15 6.528e-14
82 GASTRULATION 16 155 1.371e-15 7.781e-14
83 TUBE FORMATION 15 129 1.834e-15 1.028e-13
84 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 39 1517 2.366e-15 1.311e-13
85 REGULATION OF CELL CYCLE PROCESS 25 558 3.522e-15 1.928e-13
86 RESPONSE TO OXYGEN CONTAINING COMPOUND 37 1381 4.25e-15 2.3e-13
87 MORPHOGENESIS OF A BRANCHING STRUCTURE 16 167 4.52e-15 2.417e-13
88 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 24 513 5.212e-15 2.756e-13
89 EMBRYONIC ORGAN MORPHOGENESIS 19 279 5.849e-15 3.058e-13
90 IMMUNE RESPONSE REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 20 323 6.546e-15 3.384e-13
91 SEGMENTATION 13 89 7.182e-15 3.672e-13
92 REGULATION OF HYDROLASE ACTIVITY 36 1327 7.611e-15 3.849e-13
93 FC EPSILON RECEPTOR SIGNALING PATHWAY 15 142 7.861e-15 3.933e-13
94 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 28 799 2.948e-14 1.459e-12
95 MESENCHYME DEVELOPMENT 16 190 3.484e-14 1.689e-12
96 STEM CELL DIFFERENTIATION 16 190 3.484e-14 1.689e-12
97 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 17 228 3.945e-14 1.893e-12
98 SOMITE DEVELOPMENT 12 78 4.274e-14 2.029e-12
99 CELLULAR RESPONSE TO LIPID 22 457 4.568e-14 2.131e-12
100 REGULATION OF PROTEIN LOCALIZATION 30 950 4.579e-14 2.131e-12
101 NEGATIVE REGULATION OF GENE EXPRESSION 37 1493 4.833e-14 2.227e-12
102 DOPAMINERGIC NEURON DIFFERENTIATION 9 28 5.033e-14 2.296e-12
103 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 14 131 5.507e-14 2.488e-12
104 RESPONSE TO LIPID 29 888 5.657e-14 2.531e-12
105 BETA CATENIN TCF COMPLEX ASSEMBLY 10 43 7.291e-14 3.231e-12
106 SOMITOGENESIS 11 62 9.799e-14 4.301e-12
107 POSITIVE REGULATION OF CELL CYCLE 19 332 1.36e-13 5.914e-12
108 POSITIVE REGULATION OF CELL DEATH 24 605 1.915e-13 8.249e-12
109 NEGATIVE REGULATION OF CELL DIFFERENTIATION 24 609 2.207e-13 9.422e-12
110 REGULATION OF CELL MORPHOGENESIS 23 552 2.355e-13 9.96e-12
111 DIGESTIVE TRACT MORPHOGENESIS 10 48 2.425e-13 1.017e-11
112 MIDBRAIN DEVELOPMENT 12 90 2.537e-13 1.035e-11
113 NEGATIVE REGULATION OF CELL DEATH 28 872 2.526e-13 1.035e-11
114 RHYTHMIC PROCESS 18 298 2.519e-13 1.035e-11
115 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 26 740 2.697e-13 1.091e-11
116 REGULATION OF TRANSFERASE ACTIVITY 29 946 2.787e-13 1.118e-11
117 DORSAL VENTRAL PATTERN FORMATION 12 91 2.907e-13 1.156e-11
118 MACROMOLECULAR COMPLEX DISASSEMBLY 15 182 3.166e-13 1.248e-11
119 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 16 220 3.43e-13 1.33e-11
120 POSITIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 13 119 3.429e-13 1.33e-11
121 NEURAL TUBE FORMATION 12 94 4.334e-13 1.667e-11
122 REGULATION OF CELLULAR LOCALIZATION 33 1277 5.241e-13 1.999e-11
123 REGULATION OF CELL DEVELOPMENT 27 836 6.369e-13 2.409e-11
124 REGULATION OF MITOTIC CELL CYCLE 21 468 7.122e-13 2.673e-11
125 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 29 983 7.257e-13 2.701e-11
126 REGULATION OF ESTABLISHMENT OF PLANAR POLARITY INVOLVED IN NEURAL TUBE CLOSURE 7 14 8.248e-13 2.998e-11
127 REGULATION OF JNK CASCADE 14 159 8.209e-13 2.998e-11
128 CONVERGENT EXTENSION 7 14 8.248e-13 2.998e-11
129 RESPONSE TO GROWTH FACTOR 21 475 9.466e-13 3.414e-11
130 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 15 197 1.009e-12 3.611e-11
131 PHOSPHORYLATION 32 1228 1.034e-12 3.671e-11
132 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 14 162 1.062e-12 3.745e-11
133 CELL CYCLE 33 1316 1.2e-12 4.198e-11
134 SENSORY ORGAN MORPHOGENESIS 16 239 1.229e-12 4.267e-11
135 CELL CYCLE PROCESS 30 1081 1.276e-12 4.398e-11
136 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 19 381 1.565e-12 5.356e-11
137 MESENCHYMAL CELL DIFFERENTIATION 13 134 1.61e-12 5.467e-11
138 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 27 876 1.9e-12 6.407e-11
139 FC RECEPTOR SIGNALING PATHWAY 15 206 1.932e-12 6.466e-11
140 NEGATIVE REGULATION OF EMBRYONIC DEVELOPMENT 8 26 2.025e-12 6.73e-11
141 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 40 1977 2.406e-12 7.94e-11
142 KIDNEY MORPHOGENESIS 11 82 2.44e-12 7.994e-11
143 REGULATION OF PROTEIN CATABOLIC PROCESS 19 393 2.698e-12 8.778e-11
144 HEART MORPHOGENESIS 15 212 2.927e-12 9.459e-11
145 GLAND DEVELOPMENT 19 395 2.948e-12 9.461e-11
146 CELLULAR RESPONSE TO ACID CHEMICAL 14 175 3.065e-12 9.767e-11
147 UROGENITAL SYSTEM DEVELOPMENT 17 299 3.227e-12 1.021e-10
148 CELL ACTIVATION 22 568 3.532e-12 1.11e-10
149 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 19 406 4.764e-12 1.488e-10
150 REGULATION OF PROTEIN TARGETING 17 307 4.918e-12 1.526e-10
151 REPRODUCTIVE SYSTEM DEVELOPMENT 19 408 5.19e-12 1.599e-10
152 NEGATIVE REGULATION OF CELL PROLIFERATION 23 643 5.428e-12 1.662e-10
153 REGULATION OF PROTEIN IMPORT 14 183 5.638e-12 1.714e-10
154 CELL DEATH 28 1001 6.956e-12 2.084e-10
155 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 20 470 6.988e-12 2.084e-10
156 MESONEPHROS DEVELOPMENT 11 90 6.961e-12 2.084e-10
157 NEGATIVE REGULATION OF MOLECULAR FUNCTION 29 1079 7.182e-12 2.129e-10
158 RESPONSE TO ACID CHEMICAL 17 319 9.046e-12 2.664e-10
159 REGULATION OF CYTOPLASMIC TRANSPORT 20 481 1.062e-11 3.107e-10
160 REGULATION OF ORGANELLE ORGANIZATION 30 1178 1.108e-11 3.224e-10
161 KIDNEY EPITHELIUM DEVELOPMENT 12 125 1.367e-11 3.926e-10
162 PROTEIN COMPLEX SUBUNIT ORGANIZATION 34 1527 1.364e-11 3.926e-10
163 REGULATION OF TRANSPORT 37 1804 1.448e-11 4.132e-10
164 MITOTIC CELL CYCLE 24 766 2.81e-11 7.971e-10
165 REGULATION OF CELLULAR COMPONENT BIOGENESIS 24 767 2.886e-11 8.14e-10
166 REGULATION OF PROTEIN BINDING 13 168 2.905e-11 8.143e-10
167 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 21 573 3.258e-11 9.077e-10
168 SKELETAL SYSTEM DEVELOPMENT 19 455 3.416e-11 9.462e-10
169 REGULATION OF KINASE ACTIVITY 24 776 3.673e-11 1.011e-09
170 REGULATION OF PROTEOLYSIS 23 711 4.099e-11 1.122e-09
171 VASCULATURE DEVELOPMENT 19 469 5.736e-11 1.561e-09
172 REGULATION OF JUN KINASE ACTIVITY 10 81 5.893e-11 1.594e-09
173 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 14 218 5.957e-11 1.602e-09
174 POSITIVE REGULATION OF CELL DEVELOPMENT 19 472 6.395e-11 1.71e-09
175 REGULATION OF MAPK CASCADE 22 660 6.507e-11 1.73e-09
176 EMBRYONIC PATTERN SPECIFICATION 9 58 6.668e-11 1.763e-09
177 REGULATION OF CATABOLIC PROCESS 23 731 7.113e-11 1.87e-09
178 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 12 144 7.304e-11 1.909e-09
179 REGULATION OF OSTEOBLAST DIFFERENTIATION 11 112 7.855e-11 2.042e-09
180 REGULATION OF STEM CELL DIFFERENTIATION 11 113 8.659e-11 2.238e-09
181 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 14 229 1.146e-10 2.947e-09
182 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 21 616 1.239e-10 3.166e-09
183 CELLULAR RESPONSE TO STRESS 33 1565 1.249e-10 3.177e-09
184 CELLULAR COMPONENT MORPHOGENESIS 25 900 1.318e-10 3.333e-09
185 REGULATION OF INTRACELLULAR TRANSPORT 21 621 1.436e-10 3.612e-09
186 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 11 121 1.826e-10 4.568e-09
187 DEVELOPMENTAL INDUCTION 7 27 2e-10 4.976e-09
188 HEAD DEVELOPMENT 22 709 2.539e-10 6.284e-09
189 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 9 67 2.558e-10 6.298e-09
190 CELLULAR COMPONENT DISASSEMBLY 19 515 2.796e-10 6.846e-09
191 POSITIVE REGULATION OF CELL CYCLE PROCESS 14 247 3.113e-10 7.583e-09
192 RESPONSE TO ENDOGENOUS STIMULUS 31 1450 3.786e-10 9.176e-09
193 NEGATIVE REGULATION OF BINDING 11 131 4.314e-10 1.04e-08
194 APPENDAGE DEVELOPMENT 12 169 4.72e-10 1.126e-08
195 LIMB DEVELOPMENT 12 169 4.72e-10 1.126e-08
196 POSITIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 14 258 5.509e-10 1.308e-08
197 POSITIVE REGULATION OF CELL PROLIFERATION 23 814 5.849e-10 1.382e-08
198 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 11 135 5.963e-10 1.401e-08
199 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 8 50 6.167e-10 1.442e-08
200 CELLULAR RESPONSE TO ABIOTIC STIMULUS 14 263 7.077e-10 1.646e-08
201 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 22 750 7.291e-10 1.688e-08
202 CELLULAR RESPONSE TO EXTERNAL STIMULUS 14 264 7.436e-10 1.713e-08
203 REGULATION OF IMMUNE SYSTEM PROCESS 30 1403 7.795e-10 1.787e-08
204 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 21 684 8.283e-10 1.889e-08
205 REGULATION OF OSSIFICATION 12 178 8.581e-10 1.948e-08
206 IMMUNE SYSTEM PROCESS 36 1984 9.155e-10 2.068e-08
207 EMBRYONIC AXIS SPECIFICATION 7 33 9.336e-10 2.099e-08
208 RESPONSE TO DRUG 17 431 9.67e-10 2.163e-08
209 MAMMARY GLAND EPITHELIUM DEVELOPMENT 8 53 1.003e-09 2.211e-08
210 MUSCLE STRUCTURE DEVELOPMENT 17 432 1.002e-09 2.211e-08
211 MESONEPHRIC TUBULE MORPHOGENESIS 8 53 1.003e-09 2.211e-08
212 REGULATION OF CELL CYCLE PHASE TRANSITION 15 321 1.017e-09 2.233e-08
213 RENAL TUBULE DEVELOPMENT 9 78 1.032e-09 2.255e-08
214 NEGATIVE REGULATION OF CELL CYCLE 17 433 1.037e-09 2.255e-08
215 PROTEASOMAL PROTEIN CATABOLIC PROCESS 14 271 1.045e-09 2.262e-08
216 CELL CELL SIGNALING 22 767 1.106e-09 2.383e-08
217 POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 7 34 1.17e-09 2.474e-08
218 NEGATIVE REGULATION OF PROTEIN BINDING 9 79 1.159e-09 2.474e-08
219 REGULATION OF MESENCHYMAL CELL PROLIFERATION 7 34 1.17e-09 2.474e-08
220 BRAIN MORPHOGENESIS 7 34 1.17e-09 2.474e-08
221 REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 14 274 1.205e-09 2.538e-08
222 EYE DEVELOPMENT 15 326 1.257e-09 2.635e-08
223 PEPTIDYL SERINE MODIFICATION 11 148 1.594e-09 3.296e-08
224 DIGESTIVE SYSTEM DEVELOPMENT 11 148 1.594e-09 3.296e-08
225 OUTFLOW TRACT MORPHOGENESIS 8 56 1.583e-09 3.296e-08
226 REGULATION OF IMMUNE RESPONSE 23 858 1.611e-09 3.317e-08
227 DEVELOPMENTAL GROWTH 15 333 1.681e-09 3.446e-08
228 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 14 282 1.749e-09 3.57e-08
229 RESPONSE TO ABIOTIC STIMULUS 25 1024 1.906e-09 3.872e-08
230 NEPHRON DEVELOPMENT 10 115 1.969e-09 3.983e-08
231 IMMUNE SYSTEM DEVELOPMENT 19 582 2.131e-09 4.293e-08
232 PALATE DEVELOPMENT 9 85 2.249e-09 4.511e-08
233 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 10 117 2.332e-09 4.657e-08
234 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 14 289 2.399e-09 4.771e-08
235 SINGLE ORGANISM CELL ADHESION 17 459 2.5e-09 4.951e-08
236 STEM CELL PROLIFERATION 8 60 2.795e-09 5.487e-08
237 REGULATION OF PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 8 60 2.795e-09 5.487e-08
238 REGULATION OF STEM CELL PROLIFERATION 9 88 3.074e-09 6.01e-08
239 POSITIVE REGULATION OF MAPK CASCADE 17 470 3.565e-09 6.941e-08
240 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 19 602 3.704e-09 7.182e-08
241 POSITIVE REGULATION OF JUN KINASE ACTIVITY 8 63 4.167e-09 8.045e-08
242 POSITIVE REGULATION OF HYDROLASE ACTIVITY 23 905 4.437e-09 8.532e-08
243 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 15 360 4.843e-09 9.273e-08
244 LEUKOCYTE CELL CELL ADHESION 13 255 5.014e-09 9.561e-08
245 NEPHRON EPITHELIUM DEVELOPMENT 9 93 5.046e-09 9.584e-08
246 POSITIVE REGULATION OF KINASE ACTIVITY 17 482 5.192e-09 9.821e-08
247 REGULATION OF PROTEIN PHOSPHATASE TYPE 2A ACTIVITY 6 24 5.328e-09 1.004e-07
248 REGULATION OF PHOSPHATASE ACTIVITY 10 128 5.61e-09 1.053e-07
249 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 25 1087 6.363e-09 1.189e-07
250 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 24 1008 6.923e-09 1.289e-07
251 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 15 370 7.003e-09 1.298e-07
252 POSITIVE REGULATION OF PROTEIN CATABOLIC PROCESS 13 263 7.264e-09 1.341e-07
253 BRANCHING INVOLVED IN URETERIC BUD MORPHOGENESIS 7 44 7.927e-09 1.458e-07
254 REGULATION OF GROWTH 19 633 8.365e-09 1.532e-07
255 HEMATOPOIETIC STEM CELL PROLIFERATION 5 13 9.234e-09 1.685e-07
256 CAMERA TYPE EYE MORPHOGENESIS 9 101 1.052e-08 1.913e-07
257 REGULATION OF CATENIN IMPORT INTO NUCLEUS 6 27 1.155e-08 2.075e-07
258 AXIS ELONGATION 6 27 1.155e-08 2.075e-07
259 CENTRAL NERVOUS SYSTEM DEVELOPMENT 22 872 1.155e-08 2.075e-07
260 REGULATION OF CIRCADIAN RHYTHM 9 103 1.252e-08 2.232e-07
261 STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 9 103 1.252e-08 2.232e-07
262 REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS 11 181 1.325e-08 2.353e-07
263 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 17 514 1.344e-08 2.377e-07
264 REGULATION OF CELL GROWTH 15 391 1.465e-08 2.582e-07
265 ANTERIOR POSTERIOR AXIS SPECIFICATION 7 48 1.493e-08 2.621e-07
266 REGULATION OF FAT CELL DIFFERENTIATION 9 106 1.613e-08 2.812e-07
267 FAT CELL DIFFERENTIATION 9 106 1.613e-08 2.812e-07
268 REGULATION OF EPITHELIAL CELL PROLIFERATION 13 285 1.891e-08 3.283e-07
269 LYMPHOCYTE ACTIVATION 14 342 2.04e-08 3.529e-07
270 REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 8 77 2.11e-08 3.623e-07
271 REGULATION OF BMP SIGNALING PATHWAY 8 77 2.11e-08 3.623e-07
272 MUSCLE CELL DIFFERENTIATION 12 237 2.175e-08 3.721e-07
273 FORMATION OF PRIMARY GERM LAYER 9 110 2.236e-08 3.81e-07
274 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 15 404 2.261e-08 3.84e-07
275 GROWTH 15 410 2.747e-08 4.649e-07
276 PARAXIAL MESODERM DEVELOPMENT 5 16 3.089e-08 5.207e-07
277 LEUKOCYTE ACTIVATION 15 414 3.123e-08 5.245e-07
278 REGULATION OF FIBROBLAST PROLIFERATION 8 81 3.161e-08 5.291e-07
279 RESPIRATORY SYSTEM DEVELOPMENT 11 197 3.183e-08 5.308e-07
280 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 18 616 3.241e-08 5.385e-07
281 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 11 199 3.531e-08 5.847e-07
282 REGULATION OF CELLULAR COMPONENT MOVEMENT 20 771 3.709e-08 6.119e-07
283 MAMMARY GLAND DEVELOPMENT 9 117 3.838e-08 6.311e-07
284 SKELETAL SYSTEM MORPHOGENESIS 11 201 3.913e-08 6.411e-07
285 POSITIVE REGULATION OF EMBRYONIC DEVELOPMENT 6 33 4.194e-08 6.848e-07
286 POSITIVE REGULATION OF OSSIFICATION 8 84 4.22e-08 6.866e-07
287 REGULATION OF DEPHOSPHORYLATION 10 158 4.245e-08 6.882e-07
288 POSITIVE REGULATION OF PROTEOLYSIS 14 363 4.294e-08 6.913e-07
289 REGULATION OF APOPTOTIC SIGNALING PATHWAY 14 363 4.294e-08 6.913e-07
290 REGULATION OF CHROMATIN BINDING 5 17 4.355e-08 6.963e-07
291 ESTABLISHMENT OF TISSUE POLARITY 5 17 4.355e-08 6.963e-07
292 LOCOMOTION 24 1114 4.676e-08 7.452e-07
293 CELL CYCLE PHASE TRANSITION 12 255 4.878e-08 7.746e-07
294 EPITHELIAL CELL DIFFERENTIATION 16 495 5.113e-08 8.092e-07
295 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 9 121 5.145e-08 8.116e-07
296 RESPONSE TO CYTOKINE 19 714 5.686e-08 8.938e-07
297 INOSITOL PHOSPHATE MEDIATED SIGNALING 5 18 6e-08 9.401e-07
298 SKIN DEVELOPMENT 11 211 6.431e-08 1.004e-06
299 REGULATION OF MAP KINASE ACTIVITY 13 319 7.102e-08 1.105e-06
300 SEX DIFFERENTIATION 12 266 7.743e-08 1.201e-06
301 EMBRYONIC DIGIT MORPHOGENESIS 7 61 8.29e-08 1.282e-06
302 NEGATIVE REGULATION OF CELL GROWTH 10 170 8.482e-08 1.307e-06
303 INNER EAR MORPHOGENESIS 8 92 8.655e-08 1.329e-06
304 REGULATION OF CELL DIVISION 12 272 9.873e-08 1.511e-06
305 REGULATION OF CELL SUBSTRATE ADHESION 10 173 9.998e-08 1.525e-06
306 MESENCHYME MORPHOGENESIS 6 38 1.02e-07 1.551e-06
307 REGULATION OF MUSCLE ADAPTATION 7 63 1.041e-07 1.578e-06
308 REGULATION OF CHROMOSOME ORGANIZATION 12 278 1.251e-07 1.89e-06
309 RESPONSE TO ORGANIC CYCLIC COMPOUND 21 917 1.342e-07 2.021e-06
310 POSITIVE REGULATION OF CELL MATRIX ADHESION 6 40 1.404e-07 2.095e-06
311 POSITIVE REGULATION OF ADHERENS JUNCTION ORGANIZATION 5 21 1.405e-07 2.095e-06
312 COCHLEA MORPHOGENESIS 5 21 1.405e-07 2.095e-06
313 EYE MORPHOGENESIS 9 136 1.413e-07 2.101e-06
314 MESODERM MORPHOGENESIS 7 66 1.443e-07 2.139e-06
315 REGULATION OF CELL JUNCTION ASSEMBLY 7 68 1.779e-07 2.628e-06
316 NEGATIVE REGULATION OF BMP SIGNALING PATHWAY 6 42 1.9e-07 2.798e-06
317 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 8 102 1.939e-07 2.846e-06
318 REPRODUCTION 25 1297 1.988e-07 2.909e-06
319 RESPONSE TO INORGANIC SUBSTANCE 15 479 2.078e-07 3.031e-06
320 REGULATION OF MUSCLE TISSUE DEVELOPMENT 8 103 2.092e-07 3.032e-06
321 REGULATION OF MUSCLE ORGAN DEVELOPMENT 8 103 2.092e-07 3.032e-06
322 POSITIVE REGULATION OF GROWTH 11 238 2.175e-07 3.143e-06
323 BIOLOGICAL ADHESION 22 1032 2.231e-07 3.214e-06
324 POSITIVE REGULATION OF PROTEIN IMPORT 8 104 2.255e-07 3.228e-06
325 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 8 104 2.255e-07 3.228e-06
326 REGULATION OF CELL ADHESION 17 629 2.456e-07 3.505e-06
327 FOREBRAIN DEVELOPMENT 13 357 2.599e-07 3.699e-06
328 INNATE IMMUNE RESPONSE ACTIVATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 8 106 2.614e-07 3.708e-06
329 PROTEIN COMPLEX BIOGENESIS 23 1132 2.659e-07 3.75e-06
330 PROTEIN COMPLEX ASSEMBLY 23 1132 2.659e-07 3.75e-06
331 REGULATION OF PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 9 148 2.911e-07 4.056e-06
332 POSITIVE REGULATION OF CELL JUNCTION ASSEMBLY 5 24 2.892e-07 4.056e-06
333 CONNECTIVE TISSUE DEVELOPMENT 10 194 2.911e-07 4.056e-06
334 MALE SEX DIFFERENTIATION 9 148 2.911e-07 4.056e-06
335 RESPONSE TO ALCOHOL 13 362 3.046e-07 4.231e-06
336 NEGATIVE REGULATION OF PROTEIN CATABOLIC PROCESS 8 109 3.243e-07 4.478e-06
337 BLOOD VESSEL MORPHOGENESIS 13 364 3.243e-07 4.478e-06
338 PEPTIDYL THREONINE MODIFICATION 6 46 3.327e-07 4.58e-06
339 REGULATION OF CELLULAR RESPONSE TO HEAT 7 76 3.855e-07 5.291e-06
340 EAR MORPHOGENESIS 8 112 3.998e-07 5.472e-06
341 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 9 154 4.079e-07 5.566e-06
342 IN UTERO EMBRYONIC DEVELOPMENT 12 311 4.174e-07 5.678e-06
343 REGULATION OF ACTIN FILAMENT BASED PROCESS 12 312 4.319e-07 5.842e-06
344 POSITIVE REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 6 48 4.316e-07 5.842e-06
345 RESPONSE TO EXTRACELLULAR STIMULUS 14 441 4.623e-07 6.234e-06
346 POSITIVE REGULATION OF MAP KINASE ACTIVITY 10 207 5.292e-07 7.117e-06
347 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 5 27 5.413e-07 7.258e-06
348 REGULATION OF ADHERENS JUNCTION ORGANIZATION 6 50 5.534e-07 7.399e-06
349 MESODERM DEVELOPMENT 8 118 5.969e-07 7.958e-06
350 GASTRULATION WITH MOUTH FORMING SECOND 5 28 6.558e-07 8.693e-06
351 MORPHOGENESIS OF A POLARIZED EPITHELIUM 5 28 6.558e-07 8.693e-06
352 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 8 122 7.7e-07 1.018e-05
353 CELL CELL ADHESION 16 608 8.139e-07 1.073e-05
354 POSITIVE REGULATION OF CATABOLIC PROCESS 13 395 8.161e-07 1.073e-05
355 T CELL DIFFERENTIATION 8 123 8.195e-07 1.074e-05
356 POSITIVE REGULATION OF TRANSPORT 20 936 8.259e-07 1.079e-05
357 RESPONSE TO METAL ION 12 333 8.601e-07 1.121e-05
358 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 14 465 8.692e-07 1.13e-05
359 REGULATION OF CELL FATE SPECIFICATION 4 13 8.737e-07 1.132e-05
360 RESPONSE TO NITROGEN COMPOUND 19 859 9.645e-07 1.238e-05
361 RESPONSE TO EXTERNAL STIMULUS 29 1821 9.685e-07 1.238e-05
362 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 15 541 9.679e-07 1.238e-05
363 REGULATION OF PROTEIN STABILITY 10 221 9.622e-07 1.238e-05
364 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 15 541 9.679e-07 1.238e-05
365 REGULATION OF KIDNEY DEVELOPMENT 6 55 9.849e-07 1.249e-05
366 RESPONSE TO UV 8 126 9.844e-07 1.249e-05
367 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 9 171 9.841e-07 1.249e-05
368 HEPATICOBILIARY SYSTEM DEVELOPMENT 8 128 1.109e-06 1.403e-05
369 REGULATION OF DNA TEMPLATED TRANSCRIPTION INITIATION 5 31 1.117e-06 1.409e-05
370 EPITHELIAL CELL PROLIFERATION 7 89 1.139e-06 1.432e-05
371 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 8 129 1.177e-06 1.476e-05
372 CELL MIGRATION INVOLVED IN GASTRULATION 4 14 1.218e-06 1.523e-05
373 REGULATION OF CELL MATRIX ADHESION 7 90 1.228e-06 1.532e-05
374 COVALENT CHROMATIN MODIFICATION 12 345 1.247e-06 1.551e-05
375 REGULATION OF ORGAN FORMATION 5 32 1.318e-06 1.631e-05
376 PATTERNING OF BLOOD VESSELS 5 32 1.318e-06 1.631e-05
377 MAINTENANCE OF CELL NUMBER 8 132 1.4e-06 1.728e-05
378 APOPTOTIC SIGNALING PATHWAY 11 289 1.482e-06 1.825e-05
379 REGULATION OF VASCULATURE DEVELOPMENT 10 233 1.553e-06 1.907e-05
380 RESPONSE TO WOUNDING 15 563 1.587e-06 1.943e-05
381 LEUKOCYTE DIFFERENTIATION 11 292 1.639e-06 2.001e-05
382 REGULATION OF MESODERM DEVELOPMENT 4 15 1.653e-06 2.013e-05
383 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 6 60 1.66e-06 2.016e-05
384 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 17 724 1.714e-06 2.077e-05
385 NEGATIVE REGULATION OF GROWTH 10 236 1.743e-06 2.106e-05
386 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 7 95 1.772e-06 2.136e-05
387 REGULATION OF PROTEIN DEACETYLATION 5 34 1.804e-06 2.163e-05
388 PROTEIN DESTABILIZATION 5 34 1.804e-06 2.163e-05
389 POSITIVE REGULATION OF STEM CELL PROLIFERATION 6 61 1.832e-06 2.191e-05
390 CELLULAR RESPONSE TO RADIATION 8 137 1.854e-06 2.212e-05
391 MITOTIC CELL CYCLE CHECKPOINT 8 139 2.067e-06 2.46e-05
392 REGULATION OF CYTOSKELETON ORGANIZATION 14 502 2.137e-06 2.536e-05
393 CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS 9 188 2.162e-06 2.559e-05
394 APOPTOTIC PROCESS INVOLVED IN MORPHOGENESIS 4 16 2.193e-06 2.583e-05
395 CELL SURFACE RECEPTOR SIGNALING PATHWAY INVOLVED IN HEART DEVELOPMENT 4 16 2.193e-06 2.583e-05
396 REGULATION OF CARTILAGE DEVELOPMENT 6 63 2.219e-06 2.601e-05
397 REGULATION OF EPIDERMIS DEVELOPMENT 6 63 2.219e-06 2.601e-05
398 PROTEIN CATABOLIC PROCESS 15 579 2.24e-06 2.619e-05
399 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 11 303 2.344e-06 2.734e-05
400 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 9 190 2.359e-06 2.744e-05
401 NEGATIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 6 64 2.437e-06 2.828e-05
402 CHROMATIN ORGANIZATION 16 663 2.507e-06 2.895e-05
403 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 7 100 2.504e-06 2.895e-05
404 PROTEIN AUTOPHOSPHORYLATION 9 192 2.571e-06 2.961e-05
405 CARDIAC CHAMBER DEVELOPMENT 8 144 2.694e-06 3.095e-05
406 CELL MOTILITY 18 835 2.763e-06 3.159e-05
407 LOCALIZATION OF CELL 18 835 2.763e-06 3.159e-05
408 REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 4 17 2.854e-06 3.255e-05
409 SOMATIC STEM CELL POPULATION MAINTENANCE 6 66 2.924e-06 3.311e-05
410 CELLULAR RESPONSE TO UV 6 66 2.924e-06 3.311e-05
411 LENS DEVELOPMENT IN CAMERA TYPE EYE 6 66 2.924e-06 3.311e-05
412 PEPTIDYL AMINO ACID MODIFICATION 18 841 3.054e-06 3.449e-05
413 POSITIVE REGULATION OF PROTEIN COMPLEX ASSEMBLY 9 197 3.175e-06 3.577e-05
414 CARDIAC CHAMBER MORPHOGENESIS 7 104 3.257e-06 3.661e-05
415 PERICARDIUM DEVELOPMENT 4 18 3.653e-06 4.076e-05
416 COCHLEA DEVELOPMENT 5 39 3.643e-06 4.076e-05
417 POST ANAL TAIL MORPHOGENESIS 4 18 3.653e-06 4.076e-05
418 REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 7 108 4.191e-06 4.666e-05
419 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 10 262 4.431e-06 4.92e-05
420 AMEBOIDAL TYPE CELL MIGRATION 8 154 4.441e-06 4.92e-05
421 SKIN EPIDERMIS DEVELOPMENT 6 71 4.497e-06 4.959e-05
422 ENDODERM DEVELOPMENT 6 71 4.497e-06 4.959e-05
423 NEGATIVE REGULATION OF LOCOMOTION 10 263 4.583e-06 5.041e-05
424 REGULATION OF NON CANONICAL WNT SIGNALING PATHWAY 4 19 4.605e-06 5.054e-05
425 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 18 867 4.662e-06 5.104e-05
426 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 9 207 4.757e-06 5.196e-05
427 CHROMATIN MODIFICATION 14 539 4.856e-06 5.292e-05
428 LYMPHOCYTE DIFFERENTIATION 9 209 5.144e-06 5.592e-05
429 EMBRYONIC HEART TUBE DEVELOPMENT 6 73 5.293e-06 5.74e-05
430 GENITALIA DEVELOPMENT 5 42 5.305e-06 5.74e-05
431 WOUND HEALING 13 470 5.524e-06 5.963e-05
432 TONGUE DEVELOPMENT 4 20 5.73e-06 6.129e-05
433 TRACHEA DEVELOPMENT 4 20 5.73e-06 6.129e-05
434 POSITIVE REGULATION OF GLYCOPROTEIN METABOLIC PROCESS 4 20 5.73e-06 6.129e-05
435 BRANCHING INVOLVED IN MAMMARY GLAND DUCT MORPHOGENESIS 4 20 5.73e-06 6.129e-05
436 REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 5 43 5.974e-06 6.361e-05
437 MORPHOGENESIS OF AN EPITHELIAL SHEET 5 43 5.974e-06 6.361e-05
438 NEURAL CREST CELL DIFFERENTIATION 6 75 6.2e-06 6.586e-05
439 RESPONSE TO CALCIUM ION 7 115 6.36e-06 6.741e-05
440 REGULATION OF NEURON DIFFERENTIATION 14 554 6.641e-06 7.023e-05
441 LABYRINTHINE LAYER DEVELOPMENT 5 44 6.707e-06 7.077e-05
442 RESPONSE TO HORMONE 18 893 7e-06 7.369e-05
443 APOPTOTIC PROCESS INVOLVED IN DEVELOPMENT 4 21 7.045e-06 7.399e-05
444 SPECIFICATION OF SYMMETRY 7 117 7.128e-06 7.47e-05
445 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 22 1275 7.327e-06 7.661e-05
446 THYMOCYTE AGGREGATION 5 45 7.509e-06 7.817e-05
447 T CELL DIFFERENTIATION IN THYMUS 5 45 7.509e-06 7.817e-05
448 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 8 166 7.726e-06 8.024e-05
449 RESPONSE TO RADIATION 12 413 7.899e-06 8.186e-05
450 REGULATION OF CYTOKINE PRODUCTION 14 563 7.972e-06 8.207e-05
451 REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 10 280 7.951e-06 8.207e-05
452 POSITIVE REGULATION OF IMMUNE RESPONSE 14 563 7.972e-06 8.207e-05
453 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 7 122 9.391e-06 9.646e-05
454 MACROMOLECULAR COMPLEX ASSEMBLY 23 1398 9.576e-06 9.815e-05
455 NEGATIVE REGULATION OF PHOSPHORYLATION 12 422 9.809e-06 0.0001003
456 REGULATION OF OSTEOBLAST PROLIFERATION 4 23 1.033e-05 0.0001051
457 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 17 829 1.035e-05 0.0001051
458 SCF DEPENDENT PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 4 23 1.033e-05 0.0001051
459 STRIATED MUSCLE CELL DIFFERENTIATION 8 173 1.045e-05 0.000106
460 REGULATION OF DEVELOPMENTAL GROWTH 10 289 1.048e-05 0.000106
461 PROTEOLYSIS 21 1208 1.091e-05 0.0001101
462 ACTIVATION OF IMMUNE RESPONSE 12 427 1.104e-05 0.0001111
463 HAIR CYCLE 6 83 1.117e-05 0.000112
464 MOLTING CYCLE 6 83 1.117e-05 0.000112
465 POSITIVE REGULATION OF CYTOSKELETON ORGANIZATION 8 175 1.137e-05 0.0001137
466 CARDIAC SEPTUM MORPHOGENESIS 5 49 1.15e-05 0.0001148
467 OSTEOBLAST DIFFERENTIATION 7 126 1.16e-05 0.0001156
468 ANGIOGENESIS 10 293 1.181e-05 0.0001174
469 REGULATION OF HISTONE DEACETYLATION 4 24 1.233e-05 0.0001221
470 POSITIVE REGULATION OF DNA TEMPLATED TRANSCRIPTION INITIATION 4 24 1.233e-05 0.0001221
471 CARDIAC SEPTUM DEVELOPMENT 6 85 1.282e-05 0.0001266
472 REGULATION OF GTPASE ACTIVITY 15 673 1.365e-05 0.0001346
473 POSITIVE REGULATION OF FAT CELL DIFFERENTIATION 5 51 1.403e-05 0.000138
474 POSITIVE REGULATION OF CYTOKINE PRODUCTION 11 370 1.554e-05 0.0001526
475 NEGATIVE REGULATION OF CELL DEVELOPMENT 10 303 1.578e-05 0.0001546
476 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 5 53 1.697e-05 0.0001655
477 POSITIVE REGULATION OF FIBROBLAST PROLIFERATION 5 53 1.697e-05 0.0001655
478 DEVELOPMENTAL PROGRAMMED CELL DEATH 4 26 1.719e-05 0.000167
479 REGULATION OF CELL FATE COMMITMENT 4 26 1.719e-05 0.000167
480 REGULATION OF PROTEIN COMPLEX ASSEMBLY 11 375 1.76e-05 0.0001706
481 CALCIUM MEDIATED SIGNALING 6 90 1.781e-05 0.0001723
482 POSITIVE REGULATION OF CELL ADHESION 11 376 1.804e-05 0.0001742
483 CELLULAR RESPONSE TO LIGHT STIMULUS 6 91 1.897e-05 0.0001827
484 POSITIVE REGULATION OF INNATE IMMUNE RESPONSE 9 246 1.901e-05 0.0001827
485 RESPONSE TO OXYGEN LEVELS 10 311 1.974e-05 0.0001894
486 RESPONSE TO LITHIUM ION 4 27 2.009e-05 0.0001923
487 CELL CYCLE G2 M PHASE TRANSITION 7 138 2.098e-05 2e-04
488 PLACENTA DEVELOPMENT 7 138 2.098e-05 2e-04
489 POSITIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 8 192 2.224e-05 0.0002116
490 OSSIFICATION 9 251 2.228e-05 0.0002116
491 VENTRICULAR SEPTUM MORPHOGENESIS 4 28 2.332e-05 0.0002206
492 MAMMARY GLAND DUCT MORPHOGENESIS 4 28 2.332e-05 0.0002206
493 EPIDERMIS DEVELOPMENT 9 253 2.372e-05 0.0002238
494 CELL CYCLE CHECKPOINT 8 194 2.395e-05 0.0002256
495 REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 6 95 2.425e-05 0.0002278
496 MYOTUBE DIFFERENTIATION 5 57 2.429e-05 0.0002278
497 ANTIGEN RECEPTOR MEDIATED SIGNALING PATHWAY 8 195 2.485e-05 0.0002322
498 EAR DEVELOPMENT 8 195 2.485e-05 0.0002322
499 REGULATION OF PEPTIDE TRANSPORT 9 256 2.602e-05 0.0002426
500 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 7 144 2.76e-05 0.0002569
501 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 7 146 3.016e-05 0.0002801
502 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 6 99 3.066e-05 0.0002842
503 RESPONSE TO X RAY 4 30 3.093e-05 0.0002861
504 CARTILAGE DEVELOPMENT 7 147 3.151e-05 0.0002904
505 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 7 147 3.151e-05 0.0002904
506 NEGATIVE REGULATION OF PROTEOLYSIS 10 329 3.19e-05 0.0002933
507 POSITIVE REGULATION OF CELL GROWTH 7 148 3.292e-05 0.0003021
508 NEGATIVE REGULATION OF CATABOLIC PROCESS 8 203 3.313e-05 0.0003034
509 REGULATION OF HORMONE LEVELS 12 478 3.356e-05 0.0003068
510 REGULATION OF CELL PROJECTION ORGANIZATION 13 558 3.381e-05 0.0003085
511 ACTIVATION OF INNATE IMMUNE RESPONSE 8 204 3.431e-05 0.0003124
512 POSITIVE REGULATION OF NON CANONICAL WNT SIGNALING PATHWAY 3 11 3.44e-05 0.0003126
513 CHROMOSOME ORGANIZATION 18 1009 3.588e-05 0.0003255
514 REGULATION OF SMOOTHENED SIGNALING PATHWAY 5 62 3.664e-05 0.0003311
515 EMBRYONIC HEART TUBE MORPHOGENESIS 5 62 3.664e-05 0.0003311
516 REGULATION OF MUSCLE CELL DIFFERENTIATION 7 152 3.904e-05 0.0003514
517 REGULATION OF CHROMATIN ORGANIZATION 7 152 3.904e-05 0.0003514
518 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 8 209 4.074e-05 0.0003653
519 PALLIUM DEVELOPMENT 7 153 4.071e-05 0.0003653
520 RESPONSE TO MECHANICAL STIMULUS 8 210 4.215e-05 0.0003771
521 CELL CYCLE ARREST 7 154 4.244e-05 0.000379
522 CEREBRAL CORTEX DEVELOPMENT 6 105 4.276e-05 0.0003811
523 POSITIVE REGULATION BY HOST OF VIRAL TRANSCRIPTION 3 12 4.567e-05 0.000404
524 ROSTROCAUDAL NEURAL TUBE PATTERNING 3 12 4.567e-05 0.000404
525 TRACHEA MORPHOGENESIS 3 12 4.567e-05 0.000404
526 MAMMARY GLAND EPITHELIAL CELL PROLIFERATION 3 12 4.567e-05 0.000404
527 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 7 156 4.607e-05 0.000406
528 CELLULAR RESPONSE TO INORGANIC SUBSTANCE 7 156 4.607e-05 0.000406
529 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 8 213 4.66e-05 0.0004099
530 NEGATIVE REGULATION OF CELL CYCLE PROCESS 8 214 4.816e-05 0.0004228
531 NEURAL TUBE PATTERNING 4 34 5.137e-05 0.0004498
532 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 8 216 5.143e-05 0.0004498
533 RESPONSE TO LIGHT STIMULUS 9 280 5.228e-05 0.0004564
534 CELLULAR RESPONSE TO DRUG 5 67 5.339e-05 0.0004643
535 REGULATION OF SISTER CHROMATID SEGREGATION 5 67 5.339e-05 0.0004643
536 CELLULAR RESPONSE TO NITROGEN COMPOUND 12 505 5.701e-05 0.0004949
537 BONE REMODELING 4 35 5.773e-05 0.0004993
538 REGULATION OF GASTRULATION 4 35 5.773e-05 0.0004993
539 CELL CYCLE G1 S PHASE TRANSITION 6 111 5.841e-05 0.0005033
540 G1 S TRANSITION OF MITOTIC CELL CYCLE 6 111 5.841e-05 0.0005033
541 WHITE FAT CELL DIFFERENTIATION 3 13 5.91e-05 0.0005065
542 REGULATION OF SKELETAL MUSCLE ADAPTATION 3 13 5.91e-05 0.0005065
543 REGULATION OF BICELLULAR TIGHT JUNCTION ASSEMBLY 3 13 5.91e-05 0.0005065
544 REGULATION OF NUCLEAR DIVISION 7 163 6.086e-05 0.0005196
545 CELLULAR RESPONSE TO BIOTIC STIMULUS 7 163 6.086e-05 0.0005196
546 HEAD MORPHOGENESIS 4 36 6.464e-05 0.0005509
547 NEURAL PRECURSOR CELL PROLIFERATION 5 70 6.594e-05 0.0005609
548 PROTEIN LOCALIZATION 25 1805 6.764e-05 0.0005743
549 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 11 437 7.068e-05 0.0005969
550 NEGATIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 5 71 7.06e-05 0.0005969
551 CELL FATE SPECIFICATION 5 71 7.06e-05 0.0005969
552 NEURON DEVELOPMENT 14 687 7.109e-05 0.0005989
553 CELLULAR RESPONSE TO ALCOHOL 6 115 7.117e-05 0.0005989
554 REGULATION OF MUSCLE HYPERTROPHY 4 37 7.214e-05 0.0006059
555 POSITIVE REGULATION OF MEIOTIC CELL CYCLE 3 14 7.489e-05 0.0006267
556 REGULATION OF MONOCYTE DIFFERENTIATION 3 14 7.489e-05 0.0006267
557 TELENCEPHALON DEVELOPMENT 8 228 7.516e-05 0.0006279
558 CELLULAR RESPONSE TO STARVATION 6 117 7.834e-05 0.0006533
559 PANCREAS DEVELOPMENT 5 73 8.067e-05 0.0006714
560 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 8 232 8.485e-05 0.0007038
561 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 8 232 8.485e-05 0.0007038
562 NEGATIVE REGULATION OF DENDRITE MORPHOGENESIS 3 15 9.32e-05 0.0007703
563 REGULATION OF HAIR FOLLICLE DEVELOPMENT 3 15 9.32e-05 0.0007703
564 MAMMARY GLAND MORPHOGENESIS 4 40 9.844e-05 0.0008092
565 REGULATION OF MEIOTIC CELL CYCLE 4 40 9.844e-05 0.0008092
566 NEGATIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 4 40 9.844e-05 0.0008092
567 POSITIVE REGULATION OF MITOTIC CELL CYCLE 6 123 0.0001034 0.0008481
568 DIENCEPHALON DEVELOPMENT 5 77 0.0001041 0.0008527
569 NEGATIVE REGULATION OF TRANSPORT 11 458 0.0001071 0.000876
570 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 4 41 0.0001086 0.0008863
571 CELL DIVISION 11 460 0.0001113 0.000907
572 MORPHOGENESIS OF AN ENDOTHELIUM 3 16 0.0001142 0.0009274
573 ORGAN INDUCTION 3 16 0.0001142 0.0009274
574 NEURON PROJECTION DEVELOPMENT 12 545 0.0001173 0.000951
575 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 6 126 0.000118 0.0009552
576 EPITHELIAL CELL MORPHOGENESIS 4 42 0.0001194 0.0009648
577 CELLULAR RESPONSE TO MECHANICAL STIMULUS 5 80 0.0001248 0.001007
578 REGULATION OF MYELOID CELL DIFFERENTIATION 7 183 0.0001257 0.001012
579 MUSCLE CELL DEVELOPMENT 6 128 0.0001287 0.001034
580 REGULATION OF GLYCOPROTEIN METABOLIC PROCESS 4 43 0.0001311 0.001052
581 CELLULAR RESPONSE TO HORMONE STIMULUS 12 552 0.0001322 0.001058
582 METANEPHROS DEVELOPMENT 5 81 0.0001324 0.001059
583 CELL JUNCTION ORGANIZATION 7 185 0.0001345 0.001071
584 REGULATION OF REPRODUCTIVE PROCESS 6 129 0.0001343 0.001071
585 REGULATION OF NFAT PROTEIN IMPORT INTO NUCLEUS 3 17 0.0001381 0.001094
586 CELLULAR RESPONSE TO LITHIUM ION 3 17 0.0001381 0.001094
587 NEGATIVE REGULATION OF STEM CELL PROLIFERATION 3 17 0.0001381 0.001094
588 EPITHELIAL CELL DEVELOPMENT 7 186 0.000139 0.0011
589 JNK CASCADE 5 82 0.0001403 0.001109
590 NEGATIVE REGULATION OF KINASE ACTIVITY 8 250 0.0001422 0.001122
591 BODY MORPHOGENESIS 4 44 0.0001435 0.00113
592 COGNITION 8 251 0.0001462 0.001147
593 PROTEIN STABILIZATION 6 131 0.0001462 0.001147
594 EMBRYONIC PLACENTA DEVELOPMENT 5 83 0.0001486 0.001162
595 NIK NF KAPPAB SIGNALING 5 83 0.0001486 0.001162
596 PROTEIN DEPHOSPHORYLATION 7 190 0.0001586 0.001238
597 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 7 191 0.0001638 0.001277
598 UTERUS DEVELOPMENT 3 18 0.0001649 0.001281
599 SIGNAL TRANSDUCTION INVOLVED IN REGULATION OF GENE EXPRESSION 3 18 0.0001649 0.001281
600 REGULATION OF CHROMOSOME SEGREGATION 5 85 0.0001663 0.001287
601 POSITIVE REGULATION OF CHROMATIN MODIFICATION 5 85 0.0001663 0.001287
602 REGULATION OF NEURON APOPTOTIC PROCESS 7 192 0.0001691 0.001307
603 REGULATION OF CHONDROCYTE DIFFERENTIATION 4 46 0.0001709 0.001317
604 EMBRYONIC CRANIAL SKELETON MORPHOGENESIS 4 46 0.0001709 0.001317
605 NEGATIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 6 135 0.0001723 0.001325
606 REGULATION OF MUSCLE SYSTEM PROCESS 7 195 0.0001861 0.001426
607 POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS 4 47 0.0001859 0.001426
608 REGULATION OF NEURON PROJECTION DEVELOPMENT 10 408 0.0001891 0.001447
609 POSITIVE REGULATION OF PROTEIN EXPORT FROM NUCLEUS 3 19 0.000195 0.00149
610 REGULATION OF HORMONE SECRETION 8 262 0.0001959 0.001492
611 NEGATIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 5 88 0.0001957 0.001492
612 REGULATION OF SYNAPTIC PLASTICITY 6 140 0.0002099 0.001596
613 RESPONSE TO STEROID HORMONE 11 497 0.0002181 0.001651
614 ENDOTHELIUM DEVELOPMENT 5 90 0.0002175 0.001651
615 ESTABLISHMENT OR MAINTENANCE OF CELL POLARITY 6 141 0.0002182 0.001651
616 CELLULAR RESPONSE TO CALCIUM ION 4 49 0.0002188 0.001653
617 PLATELET ACTIVATION 6 142 0.0002267 0.001709
618 REGULATION OF DNA METABOLIC PROCESS 9 340 0.000227 0.001709
619 METANEPHRIC EPITHELIUM DEVELOPMENT 3 20 0.0002284 0.001717
620 REGULATION OF SKELETAL MUSCLE TISSUE DEVELOPMENT 4 50 0.0002368 0.001763
621 RAS PROTEIN SIGNAL TRANSDUCTION 6 143 0.0002355 0.001763
622 FACE DEVELOPMENT 4 50 0.0002368 0.001763
623 ENDODERM FORMATION 4 50 0.0002368 0.001763
624 POSITIVE REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 4 50 0.0002368 0.001763
625 RHO PROTEIN SIGNAL TRANSDUCTION 4 50 0.0002368 0.001763
626 POSITIVE REGULATION OF LOCOMOTION 10 420 0.0002386 0.001774
627 NEURON PROJECTION GUIDANCE 7 205 0.0002526 0.001875
628 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 5 93 0.0002535 0.001875
629 REGULATION OF DNA BINDING 5 93 0.0002535 0.001875
630 POSITIVE REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 4 51 0.0002557 0.001889
631 RESPONSE TO ESTRADIOL 6 146 0.0002634 0.001939
632 T CELL RECEPTOR SIGNALING PATHWAY 6 146 0.0002634 0.001939
633 POSITIVE REGULATION OF REPRODUCTIVE PROCESS 4 52 0.0002757 0.002027
634 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 13 689 0.0002771 0.002034
635 NEGATIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 5 95 0.0002799 0.002051
636 REGULATION OF PEPTIDE SECRETION 7 209 0.0002841 0.002079
637 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 9 351 0.0002871 0.002097
638 REGULATION OF HAIR CYCLE 3 22 0.0003058 0.00221
639 MODULATION OF TRANSCRIPTION IN OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 3 22 0.0003058 0.00221
640 POSITIVE REGULATION OF MUSCLE HYPERTROPHY 3 22 0.0003058 0.00221
641 SOMATIC STEM CELL DIVISION 3 22 0.0003058 0.00221
642 POSITIVE REGULATION OF CARDIAC MUSCLE HYPERTROPHY 3 22 0.0003058 0.00221
643 REGULATION OF STRIATED MUSCLE CELL APOPTOTIC PROCESS 3 22 0.0003058 0.00221
644 EMBRYONIC PLACENTA MORPHOGENESIS 3 22 0.0003058 0.00221
645 GLAND MORPHOGENESIS 5 97 0.0003084 0.002225
646 CELLULAR RESPONSE TO CYTOKINE STIMULUS 12 606 0.0003114 0.002243
647 REGULATION OF SECRETION 13 699 0.0003182 0.002289
648 VENTRICULAR SEPTUM DEVELOPMENT 4 54 0.0003191 0.002291
649 POSITIVE REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS 5 98 0.0003234 0.002319
650 REGULATION OF INNATE IMMUNE RESPONSE 9 357 0.000325 0.002327
651 INTRINSIC APOPTOTIC SIGNALING PATHWAY 6 152 0.0003271 0.002338
652 CRANIAL SKELETAL SYSTEM DEVELOPMENT 4 55 0.0003425 0.002445
653 REGULATION OF METANEPHROS DEVELOPMENT 3 23 0.0003502 0.002495
654 RESPONSE TO STARVATION 6 154 0.0003508 0.002496
655 SMAD PROTEIN SIGNAL TRANSDUCTION 4 56 0.0003672 0.0026
656 INOSITOL PHOSPHATE METABOLIC PROCESS 4 56 0.0003672 0.0026
657 RESPONSE TO ESTROGEN 7 218 0.0003666 0.0026
658 POSITIVE REGULATION OF DEFENSE RESPONSE 9 364 0.0003744 0.002648
659 NEGATIVE REGULATION OF CELLULAR CATABOLIC PROCESS 6 156 0.0003758 0.002649
660 BONE DEVELOPMENT 6 156 0.0003758 0.002649
661 APOPTOTIC MITOCHONDRIAL CHANGES 4 57 0.0003931 0.002767
662 EMBRYONIC CAMERA TYPE EYE MORPHOGENESIS 3 24 0.0003984 0.002793
663 SYSTEM PROCESS 23 1785 0.0003986 0.002793
664 CARDIAC EPITHELIAL TO MESENCHYMAL TRANSITION 3 24 0.0003984 0.002793
665 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 9 368 0.0004054 0.002836
666 REGULATION OF PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 5 103 0.000407 0.002844
667 PROTEIN ACYLATION 6 159 0.0004159 0.002902
668 SECOND MESSENGER MEDIATED SIGNALING 6 160 0.00043 0.002995
669 REGENERATION 6 161 0.0004445 0.003088
670 ODONTOGENESIS 5 105 0.0004447 0.003088
671 SPINDLE CHECKPOINT 3 25 0.0004508 0.003103
672 FOREBRAIN REGIONALIZATION 3 25 0.0004508 0.003103
673 REGULATION OF CELL CYCLE G2 M PHASE TRANSITION 4 59 0.0004487 0.003103
674 REGULATION OF TRANSFORMING GROWTH FACTOR BETA PRODUCTION 3 25 0.0004508 0.003103
675 REGULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 3 25 0.0004508 0.003103
676 VASCULOGENESIS 4 59 0.0004487 0.003103
677 CARDIAC VENTRICLE DEVELOPMENT 5 106 0.0004644 0.003192
678 MACROMOLECULE CATABOLIC PROCESS 15 926 0.0004741 0.003254
679 NEGATIVE REGULATION OF CELL DIVISION 4 60 0.0004785 0.003274
680 CHONDROCYTE DIFFERENTIATION 4 60 0.0004785 0.003274
681 CELL SUBSTRATE ADHESION 6 164 0.0004902 0.003349
682 MODULATION OF SYNAPTIC TRANSMISSION 8 301 0.0004962 0.003385
683 REGULATION OF CELL CYCLE ARREST 5 108 0.000506 0.003447
684 NEGATIVE REGULATION OF CARTILAGE DEVELOPMENT 3 26 0.0005073 0.003451
685 TAXIS 10 464 0.0005229 0.003552
686 RESPONSE TO HYDROGEN PEROXIDE 5 109 0.0005278 0.00358
687 REGULATION OF LEUKOCYTE DIFFERENTIATION 7 232 0.0005319 0.003602
688 POSITIVE REGULATION OF MITOCHONDRION ORGANIZATION 6 167 0.0005395 0.003648
689 POSITIVE REGULATION OF NUCLEAR DIVISION 4 62 0.0005423 0.003663
690 RESPONSE TO ENDOPLASMIC RETICULUM STRESS 7 233 0.0005457 0.00368
691 POSITIVE REGULATION OF NEURON DIFFERENTIATION 8 306 0.000553 0.003724
692 RESPONSE TO CARBOHYDRATE 6 168 0.0005567 0.003738
693 REGULATION OF AXONOGENESIS 6 168 0.0005567 0.003738
694 REGULATION OF ENDOTHELIAL CELL DIFFERENTIATION 3 27 0.0005682 0.003804
695 NEGATIVE REGULATION OF FIBROBLAST PROLIFERATION 3 27 0.0005682 0.003804
696 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 5 111 0.0005735 0.003834
697 NEUROEPITHELIAL CELL DIFFERENTIATION 4 63 0.0005764 0.003848
698 REGULATION OF PROTEIN SECRETION 9 389 0.0006043 0.004028
699 PLACENTA BLOOD VESSEL DEVELOPMENT 3 28 0.0006336 0.0042
700 NEGATIVE REGULATION OF CHROMOSOME SEGREGATION 3 28 0.0006336 0.0042
701 NEGATIVE REGULATION OF DENDRITE DEVELOPMENT 3 28 0.0006336 0.0042
702 METANEPHROS MORPHOGENESIS 3 28 0.0006336 0.0042
703 NEGATIVE REGULATION OF AXONOGENESIS 4 65 0.0006491 0.004296
704 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 5 115 0.0006737 0.004446
705 RESPONSE TO INTERLEUKIN 1 5 115 0.0006737 0.004446
706 NEGATIVE REGULATION OF HYDROLASE ACTIVITY 9 397 0.0006985 0.004604
707 REGULATION OF MEIOTIC NUCLEAR DIVISION 3 29 0.0007036 0.004611
708 STEM CELL DIVISION 3 29 0.0007036 0.004611
709 REGULATION OF HEART MORPHOGENESIS 3 29 0.0007036 0.004611
710 FEMALE SEX DIFFERENTIATION 5 116 0.0007007 0.004611
711 POSITIVE REGULATION OF NEURON DEATH 4 67 0.0007281 0.004754
712 NEGATIVE REGULATION OF CYTOPLASMIC TRANSPORT 5 117 0.0007285 0.004754
713 REGULATION OF DNA TEMPLATED TRANSCRIPTION IN RESPONSE TO STRESS 4 67 0.0007281 0.004754
714 MITOCHONDRIAL TRANSPORT 6 177 0.000732 0.004771
715 NEURON PROJECTION MORPHOGENESIS 9 402 0.0007633 0.004967
716 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 4 68 0.00077 0.004991
717 MULTICELLULAR ORGANISM REPRODUCTION 13 768 0.0007701 0.004991
718 POSITIVE REGULATION OF CELL CYCLE PHASE TRANSITION 4 68 0.00077 0.004991
719 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE BY P53 CLASS MEDIATOR 3 30 0.0007784 0.005002
720 ESTABLISHMENT OR MAINTENANCE OF EPITHELIAL CELL APICAL BASAL POLARITY 3 30 0.0007784 0.005002
721 SMOOTH MUSCLE CELL DIFFERENTIATION 3 30 0.0007784 0.005002
722 POSITIVE REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 3 30 0.0007784 0.005002
723 NEGATIVE REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 3 30 0.0007784 0.005002
724 MYOTUBE CELL DEVELOPMENT 3 30 0.0007784 0.005002
725 NEGATIVE REGULATION OF OSSIFICATION 4 69 0.0008136 0.005214
726 POSITIVE REGULATION OF AXONOGENESIS 4 69 0.0008136 0.005214
727 REGULATION OF DENDRITE DEVELOPMENT 5 120 0.0008168 0.005227
728 RESPONSE TO KETONE 6 182 0.0008464 0.00541
729 MUSCLE ORGAN MORPHOGENESIS 4 70 0.0008589 0.005467
730 INTERFERON GAMMA MEDIATED SIGNALING PATHWAY 4 70 0.0008589 0.005467
731 REGULATION OF MEMBRANE PERMEABILITY 4 70 0.0008589 0.005467
732 REGULATION OF NEURON DEATH 7 252 0.0008658 0.005503
733 CELLULAR RESPONSE TO INTERFERON GAMMA 5 122 0.0008799 0.005586
734 CATABOLIC PROCESS 22 1773 0.0008999 0.005705
735 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE 4 71 0.000906 0.005735
736 POSITIVE REGULATION OF DNA METABOLIC PROCESS 6 185 0.0009213 0.005824
737 EMBRYONIC FORELIMB MORPHOGENESIS 3 32 0.0009426 0.005943
738 ADIPOSE TISSUE DEVELOPMENT 3 32 0.0009426 0.005943
739 ENDOTHELIAL CELL DIFFERENTIATION 4 72 0.0009548 0.006012
740 POSITIVE REGULATION OF PROTEIN BINDING 4 73 0.001005 0.006314
741 G1 DNA DAMAGE CHECKPOINT 4 73 0.001005 0.006314
742 MYELOID CELL DIFFERENTIATION 6 189 0.001029 0.006453
743 REGULATION OF PROTEIN EXPORT FROM NUCLEUS 3 33 0.001032 0.006456
744 EMBRYONIC EYE MORPHOGENESIS 3 33 0.001032 0.006456
745 POSITIVE REGULATION OF BINDING 5 127 0.001054 0.006581
746 REGULATION OF DENDRITE MORPHOGENESIS 4 74 0.001058 0.006581
747 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 4 74 0.001058 0.006581
748 CELL CELL JUNCTION ASSEMBLY 4 74 0.001058 0.006581
749 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION 5 128 0.001091 0.006779
750 SYNAPTIC SIGNALING 9 424 0.001109 0.006882
751 CELL PROJECTION ORGANIZATION 14 902 0.001115 0.006907
752 ORGAN FORMATION 3 34 0.001127 0.006963
753 PROTEIN ACETYLATION 5 129 0.00113 0.006963
754 NEGATIVE REGULATION OF MITOTIC NUCLEAR DIVISION 3 34 0.001127 0.006963
755 CELL JUNCTION ASSEMBLY 5 129 0.00113 0.006963
756 BEHAVIOR 10 516 0.001175 0.007233
757 CELLULAR MACROMOLECULE LOCALIZATION 17 1234 0.001217 0.00748
758 RESPONSE TO MINERALOCORTICOID 3 35 0.001227 0.007525
759 EMBRYONIC CAMERA TYPE EYE DEVELOPMENT 3 35 0.001227 0.007525
760 POSITIVE REGULATION OF CELL DIVISION 5 132 0.001252 0.007663
761 T CELL PROLIFERATION 3 36 0.001333 0.008109
762 NEGATIVE REGULATION OF MUSCLE ORGAN DEVELOPMENT 3 36 0.001333 0.008109
763 NEGATIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 3 36 0.001333 0.008109
764 POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 3 36 0.001333 0.008109
765 POSITIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 3 36 0.001333 0.008109
766 RESPONSE TO OXIDATIVE STRESS 8 352 0.001364 0.008287
767 CELLULAR RESPONSE TO DNA DAMAGE STIMULUS 12 720 0.001407 0.008534
768 NEGATIVE REGULATION OF VASCULATURE DEVELOPMENT 4 80 0.001414 0.008569
769 MUSCLE TISSUE DEVELOPMENT 7 275 0.001434 0.008679
770 MYOBLAST DIFFERENTIATION 3 37 0.001444 0.008695
771 NEGATIVE REGULATION OF EPITHELIAL CELL DIFFERENTIATION 3 37 0.001444 0.008695
772 ESTABLISHMENT OR MAINTENANCE OF APICAL BASAL CELL POLARITY 3 37 0.001444 0.008695
773 ESTABLISHMENT OR MAINTENANCE OF BIPOLAR CELL POLARITY 3 37 0.001444 0.008695
774 CIRCADIAN RHYTHM 5 137 0.001476 0.008862
775 HINDBRAIN DEVELOPMENT 5 137 0.001476 0.008862
776 POSITIVE REGULATION OF MYELOID CELL DIFFERENTIATION 4 81 0.001481 0.00888
777 MUSCLE ORGAN DEVELOPMENT 7 277 0.001495 0.008953
778 POSITIVE REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 3 38 0.001561 0.009314
779 SUBSTRATE ADHESION DEPENDENT CELL SPREADING 3 38 0.001561 0.009314
780 REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 3 38 0.001561 0.009314
781 NEGATIVE REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 5 139 0.001574 0.009375
782 POSITIVE REGULATION OF VIRAL TRANSCRIPTION 3 39 0.001684 0.009995
783 NEGATIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 3 39 0.001684 0.009995
784 TRABECULA MORPHOGENESIS 3 39 0.001684 0.009995
NumGOOverlapSizeP ValueAdj. P Value
1 FRIZZLED BINDING 21 36 2.166e-38 2.012e-35
2 BETA CATENIN BINDING 19 84 3.899e-25 1.811e-22
3 WNT PROTEIN BINDING 13 31 1.411e-21 4.369e-19
4 WNT ACTIVATED RECEPTOR ACTIVITY 11 22 1.665e-19 3.867e-17
5 G PROTEIN COUPLED RECEPTOR BINDING 21 259 5.408e-18 1.005e-15
6 TRANSCRIPTION FACTOR BINDING 24 524 8.325e-15 1.289e-12
7 RECEPTOR AGONIST ACTIVITY 8 16 1.754e-14 2.328e-12
8 PROTEIN SERINE THREONINE KINASE ACTIVITY 22 445 2.658e-14 3.086e-12
9 ENZYME BINDING 39 1737 1.913e-13 1.777e-11
10 RECEPTOR BINDING 36 1476 1.906e-13 1.777e-11
11 PROTEIN KINASE ACTIVITY 23 640 4.936e-12 4.169e-10
12 RECEPTOR REGULATOR ACTIVITY 9 45 5.925e-12 4.587e-10
13 RECEPTOR ACTIVATOR ACTIVITY 8 32 1.323e-11 9.452e-10
14 REGULATORY REGION NUCLEIC ACID BINDING 25 818 1.732e-11 1.149e-09
15 MOLECULAR FUNCTION REGULATOR 31 1353 6.789e-11 4.204e-09
16 SIGNAL TRANSDUCER ACTIVITY 35 1731 9.156e-11 5.316e-09
17 KINASE BINDING 20 606 6.337e-10 3.463e-08
18 RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 10 104 7.289e-10 3.762e-08
19 KINASE ACTIVITY 23 842 1.123e-09 5.491e-08
20 PROTEIN PHOSPHATASE TYPE 2A REGULATOR ACTIVITY 6 21 2.18e-09 1.013e-07
21 PROTEIN DOMAIN SPECIFIC BINDING 19 624 6.637e-09 2.936e-07
22 SMAD BINDING 8 72 1.231e-08 5.197e-07
23 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 23 992 2.456e-08 9.921e-07
24 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 18 629 4.446e-08 1.721e-06
25 CORE PROMOTER PROXIMAL REGION DNA BINDING 14 371 5.627e-08 2.091e-06
26 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 13 315 6.131e-08 2.191e-06
27 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 17 588 9.445e-08 3.25e-06
28 R SMAD BINDING 5 23 2.3e-07 7.632e-06
29 I SMAD BINDING 4 11 4.071e-07 1.304e-05
30 UBIQUITIN LIKE PROTEIN LIGASE BINDING 11 264 6.105e-07 1.829e-05
31 GAMMA CATENIN BINDING 4 12 6.077e-07 1.829e-05
32 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 23 1199 7.268e-07 2.11e-05
33 ARMADILLO REPEAT DOMAIN BINDING 4 13 8.737e-07 2.46e-05
34 PHOSPHATASE REGULATOR ACTIVITY 7 87 9.753e-07 2.665e-05
35 MAP KINASE ACTIVITY 4 14 1.218e-06 3.15e-05
36 ACTIVATING TRANSCRIPTION FACTOR BINDING 6 57 1.221e-06 3.15e-05
37 PROTEIN DIMERIZATION ACTIVITY 22 1149 1.36e-06 3.414e-05
38 RNA POLYMERASE II ACTIVATING TRANSCRIPTION FACTOR BINDING 5 36 2.42e-06 5.916e-05
39 DOUBLE STRANDED DNA BINDING 17 764 3.532e-06 8.413e-05
40 SEQUENCE SPECIFIC DNA BINDING 20 1037 3.953e-06 9.181e-05
41 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 11 328 5.011e-06 0.0001135
42 RHO GTPASE BINDING 6 78 7.792e-06 0.0001724
43 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 9 226 9.671e-06 0.0002089
44 RECEPTOR SIGNALING PROTEIN ACTIVITY 8 172 1.002e-05 0.0002116
45 CALMODULIN BINDING 8 179 1.34e-05 0.0002706
46 CHROMATIN BINDING 12 435 1.328e-05 0.0002706
47 PDZ DOMAIN BINDING 6 90 1.781e-05 0.000352
48 ENZYME REGULATOR ACTIVITY 18 959 1.834e-05 0.000355
49 CALMODULIN DEPENDENT PROTEIN KINASE ACTIVITY 4 28 2.332e-05 0.0004422
50 ADENYL NUCLEOTIDE BINDING 23 1514 3.413e-05 0.0006341
51 PHOSPHOLIPASE C ACTIVITY 4 31 3.535e-05 0.0006438
52 PROTEIN SERINE THREONINE PHOSPHATASE ACTIVITY 5 64 4.276e-05 0.0007639
53 CALCIUM DEPENDENT PROTEIN KINASE ACTIVITY 3 12 4.567e-05 0.0008004
54 TRANSCRIPTION COACTIVATOR ACTIVITY 9 296 8.01e-05 0.001378
55 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR BINDING 3 15 9.32e-05 0.001574
56 RIBONUCLEOTIDE BINDING 25 1860 0.0001095 0.001817
57 PROTEIN KINASE C ACTIVITY 3 16 0.0001142 0.001861
58 RECEPTOR SIGNALING PROTEIN SERINE THREONINE KINASE ACTIVITY 5 92 0.000241 0.003861
59 ENHANCER BINDING 5 93 0.0002535 0.003992
60 IDENTICAL PROTEIN BINDING 18 1209 0.0003473 0.005378
61 MITOGEN ACTIVATED PROTEIN KINASE BINDING 3 24 0.0003984 0.005875
62 REPRESSING TRANSCRIPTION FACTOR BINDING 4 57 0.0003931 0.005875
63 TRANSCRIPTION COREPRESSOR ACTIVITY 7 221 0.0003979 0.005875
64 PHOSPHORIC ESTER HYDROLASE ACTIVITY 9 368 0.0004054 0.005884
65 PROTEIN HOMODIMERIZATION ACTIVITY 13 722 0.0004329 0.006187
66 DRUG BINDING 5 109 0.0005278 0.007429
67 HORMONE RECEPTOR BINDING 6 168 0.0005567 0.007524
68 PROTEIN HETERODIMERIZATION ACTIVITY 10 468 0.0005588 0.007524
69 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 6 168 0.0005567 0.007524
70 BHLH TRANSCRIPTION FACTOR BINDING 3 28 0.0006336 0.008291
71 CADHERIN BINDING 3 28 0.0006336 0.008291
72 P53 BINDING 4 67 0.0007281 0.009394
73 NF KAPPAB BINDING 3 30 0.0007784 0.009905
NumGOOverlapSizeP ValueAdj. P Value
1 WNT SIGNALOSOME 9 11 4.367e-19 2.55e-16
2 BETA CATENIN DESTRUCTION COMPLEX 8 14 4.135e-15 1.207e-12
3 TRANSCRIPTION FACTOR COMPLEX 16 298 3.464e-11 6.743e-09
4 PROTEINACEOUS EXTRACELLULAR MATRIX 17 356 5.089e-11 7.429e-09
5 EXTRACELLULAR MATRIX 18 426 9.746e-11 1.138e-08
6 NUCLEAR CHROMATIN 15 291 2.622e-10 2.552e-08
7 PHOSPHATASE COMPLEX 8 48 4.378e-10 3.653e-08
8 CHROMATIN 17 441 1.369e-09 9.991e-08
9 PROTEIN PHOSPHATASE TYPE 2A COMPLEX 6 20 1.565e-09 1.016e-07
10 ENDOCYTIC VESICLE MEMBRANE 11 152 2.116e-09 1.236e-07
11 CHROMOSOME 23 880 2.61e-09 1.27e-07
12 CATALYTIC COMPLEX 25 1038 2.511e-09 1.27e-07
13 ENDOCYTIC VESICLE 12 256 5.092e-08 2.287e-06
14 TRANSCRIPTIONAL REPRESSOR COMPLEX 7 74 3.205e-07 1.337e-05
15 NUCLEAR CHROMOSOME 15 523 6.337e-07 2.467e-05
16 NUCLEAR TRANSCRIPTION FACTOR COMPLEX 8 127 1.045e-06 3.815e-05
17 LATERAL PLASMA MEMBRANE 5 50 1.271e-05 0.0004124
18 SYNAPSE 16 754 1.268e-05 0.0004124
19 RNA POLYMERASE II TRANSCRIPTION FACTOR COMPLEX 6 101 3.434e-05 0.001055
20 SCF UBIQUITIN LIGASE COMPLEX 4 34 5.137e-05 0.0015
21 VESICLE MEMBRANE 12 512 6.502e-05 0.001726
22 INTRACELLULAR VESICLE 20 1259 6.501e-05 0.001726
23 EXCITATORY SYNAPSE 7 197 0.0001981 0.00482
24 CELL SURFACE 14 757 0.0001963 0.00482
25 PROTEIN KINASE COMPLEX 5 90 0.0002175 0.004885
26 EXTRACELLULAR SPACE 20 1376 0.0002161 0.004885
27 GOLGI LUMEN 5 94 0.0002665 0.005764
28 NEURONAL POSTSYNAPTIC DENSITY 4 53 0.0002969 0.005973
29 CYTOPLASMIC VESICLE PART 12 601 0.0002889 0.005973
30 NUCLEAR MEMBRANE 8 280 0.0003068 0.005973
31 TRANSFERASE COMPLEX 13 703 0.0003361 0.006331
32 NUCLEOPLASM PART 13 708 0.0003595 0.006562
33 NUCLEAR EUCHROMATIN 3 24 0.0003984 0.00686
34 MICROTUBULE ORGANIZING CENTER 12 623 0.0003994 0.00686
35 HISTONE DEACETYLASE COMPLEX 4 61 0.0005097 0.008505
36 CELL CELL JUNCTION 9 383 0.0005407 0.008771
37 LAMELLIPODIUM 6 172 0.0006301 0.009945
38 CLATHRIN COATED ENDOCYTIC VESICLE 4 65 0.0006491 0.009976

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04310_Wnt_signaling_pathway 121 387 4.906e-217 8.683e-215
2 hsa04916_Melanogenesis 45 387 5.78e-46 5.116e-44
3 hsa04340_Hedgehog_signaling_pathway 22 387 1.502e-15 8.864e-14
4 hsa04114_Oocyte_meiosis 20 387 1.969e-13 8.713e-12
5 hsa04010_MAPK_signaling_pathway 19 387 2.06e-12 7.292e-11
6 hsa04720_Long.term_potentiation 18 387 2.023e-11 5.968e-10
7 hsa04020_Calcium_signaling_pathway 16 387 1.598e-09 2.828e-08
8 hsa04510_Focal_adhesion 16 387 1.598e-09 2.828e-08
9 hsa04520_Adherens_junction 16 387 1.598e-09 2.828e-08
10 hsa04912_GnRH_signaling_pathway 16 387 1.598e-09 2.828e-08
11 hsa04012_ErbB_signaling_pathway 13 387 6.487e-07 6.754e-06
12 hsa04110_Cell_cycle 13 387 6.487e-07 6.754e-06
13 hsa04350_TGF.beta_signaling_pathway 13 387 6.487e-07 6.754e-06
14 hsa04360_Axon_guidance 13 387 6.487e-07 6.754e-06
15 hsa04660_T_cell_receptor_signaling_pathway 13 387 6.487e-07 6.754e-06
16 hsa04722_Neurotrophin_signaling_pathway 13 387 6.487e-07 6.754e-06
17 hsa04971_Gastric_acid_secretion 13 387 6.487e-07 6.754e-06
18 hsa04062_Chemokine_signaling_pathway 12 387 4.085e-06 3.287e-05
19 hsa04270_Vascular_smooth_muscle_contraction 12 387 4.085e-06 3.287e-05
20 hsa04370_VEGF_signaling_pathway 12 387 4.085e-06 3.287e-05
21 hsa04650_Natural_killer_cell_mediated_cytotoxicity 12 387 4.085e-06 3.287e-05
22 hsa04662_B_cell_receptor_signaling_pathway 12 387 4.085e-06 3.287e-05
23 hsa04380_Osteoclast_differentiation 11 387 2.353e-05 0.0001811
24 hsa04530_Tight_junction 9 387 0.0005824 0.003682
25 hsa04540_Gap_junction 9 387 0.0005824 0.003682
26 hsa04730_Long.term_depression 9 387 0.0005824 0.003682
27 hsa04970_Salivary_secretion 9 387 0.0005824 0.003682
28 hsa04972_Pancreatic_secretion 9 387 0.0005824 0.003682
29 hsa04670_Leukocyte_transendothelial_migration 8 387 0.002464 0.01504
30 hsa03015_mRNA_surveillance_pathway 7 387 0.009241 0.05112
31 hsa04070_Phosphatidylinositol_signaling_system 7 387 0.009241 0.05112
32 hsa04330_Notch_signaling_pathway 7 387 0.009241 0.05112
33 hsa04210_Apoptosis 6 387 0.03035 0.1393
34 hsa04620_Toll.like_receptor_signaling_pathway 6 387 0.03035 0.1393
35 hsa04630_Jak.STAT_signaling_pathway 6 387 0.03035 0.1393
36 hsa04664_Fc_epsilon_RI_signaling_pathway 6 387 0.03035 0.1393
37 hsa04810_Regulation_of_actin_cytoskeleton 6 387 0.03035 0.1393
38 hsa04910_Insulin_signaling_pathway 6 387 0.03035 0.1393
39 hsa04740_Olfactory_transduction 6 388 0.03068 0.1393
40 hsa04115_p53_signaling_pathway 5 387 0.08609 0.3463
41 hsa04120_Ubiquitin_mediated_proteolysis 5 387 0.08609 0.3463
42 hsa04141_Protein_processing_in_endoplasmic_reticulum 5 387 0.08609 0.3463
43 hsa04710_Circadian_rhythm_._mammal 5 387 0.08609 0.3463
44 hsa04914_Progesterone.mediated_oocyte_maturation 5 387 0.08609 0.3463
45 hsa00562_Inositol_phosphate_metabolism 4 387 0.2073 0.7646
46 hsa04621_NOD.like_receptor_signaling_pathway 4 387 0.2073 0.7646
47 hsa04622_RIG.I.like_receptor_signaling_pathway 4 387 0.2073 0.7646
48 hsa04666_Fc_gamma_R.mediated_phagocytosis 4 387 0.2073 0.7646
49 hsa04144_Endocytosis 3 387 0.416 1
50 hsa04742_Taste_transduction 3 387 0.416 1
51 hsa04920_Adipocytokine_signaling_pathway 3 387 0.416 1
52 hsa04960_Aldosterone.regulated_sodium_reabsorption 3 387 0.416 1
53 hsa03008_Ribosome_biogenesis_in_eukaryotes 2 387 0.6824 1
54 hsa04962_Vasopressin.regulated_water_reabsorption 2 387 0.6824 1
55 hsa04973_Carbohydrate_digestion_and_absorption 2 387 0.6824 1
56 hsa04976_Bile_secretion 2 387 0.6824 1

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1 RP11-284N8.3 hsa-let-7d-3p;hsa-miR-1323;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-200c-3p;hsa-miR-23b-3p;hsa-miR-409-3p;hsa-miR-551b-5p;hsa-miR-590-5p;hsa-miR-93-5p;hsa-miR-96-5p 11 PRKACB Sponge network 1.749 0 0.841 0 0.869
2

TUG1

 hsa-miR-1299;hsa-miR-143-3p;hsa-miR-154-5p;hsa-miR-190b;hsa-miR-193a-3p;hsa-miR-195-5p;hsa-miR-198;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-501-5p;hsa-miR-548c-5p;hsa-miR-551b-5p;hsa-miR-588 13 NFAT5 Sponge network -0.266 0.05426 -0.09 0.53721 0.794
3

TUG1

 hsa-miR-1299;hsa-miR-1322;hsa-miR-133b;hsa-miR-140-3p;hsa-miR-154-5p;hsa-miR-195-3p;hsa-miR-297;hsa-miR-367-3p;hsa-miR-376a-5p;hsa-miR-512-5p;hsa-miR-548d-3p;hsa-miR-551b-5p;hsa-miR-888-5p 13 TBL1XR1 Sponge network -0.266 0.05426 -0.385 0.0325 0.772
4 LINC00657 hsa-miR-1299;hsa-miR-143-3p;hsa-miR-193a-3p;hsa-miR-195-5p;hsa-miR-198;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-501-5p;hsa-miR-588;hsa-miR-605-5p 10 NFAT5 Sponge network -0.526 0.03498 -0.09 0.53721 0.761
5 GAS5 hsa-miR-1299;hsa-miR-143-3p;hsa-miR-148a-3p;hsa-miR-154-5p;hsa-miR-15a-5p;hsa-miR-193a-3p;hsa-miR-195-5p;hsa-miR-198;hsa-miR-27a-3p;hsa-miR-29a-3p;hsa-miR-29b-3p 11 NFAT5 Sponge network -0.299 0.08203 -0.09 0.53721 0.732
6

TUG1

 hsa-let-7f-2-3p;hsa-miR-1228-3p;hsa-miR-1299;hsa-miR-1322;hsa-miR-195-3p;hsa-miR-501-5p;hsa-miR-548c-5p;hsa-miR-551b-5p;hsa-miR-561-3p;hsa-miR-888-5p 10 SMAD2 Sponge network -0.266 0.05426 -0.161 0.13545 0.731
7 RP11-83A24.2 hsa-miR-1299;hsa-miR-143-3p;hsa-miR-148a-3p;hsa-miR-154-5p;hsa-miR-15a-5p;hsa-miR-193a-3p;hsa-miR-195-5p;hsa-miR-198;hsa-miR-27a-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-501-5p;hsa-miR-588;hsa-miR-605-5p 14 NFAT5 Sponge network -0.096 0.48063 -0.09 0.53721 0.717
8 AC009948.5 hsa-miR-1299;hsa-miR-1322;hsa-miR-140-3p;hsa-miR-154-5p;hsa-miR-195-3p;hsa-miR-297;hsa-miR-376a-5p;hsa-miR-376c-3p;hsa-miR-512-5p;hsa-miR-548b-3p;hsa-miR-551b-5p;hsa-miR-888-5p 12 TBL1XR1 Sponge network -0.339 0.00631 -0.385 0.0325 0.694
9 SNHG14 hsa-let-7d-5p;hsa-let-7f-5p;hsa-miR-1231;hsa-miR-1244;hsa-miR-1290;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-92b-3p 10 FZD4 Sponge network 0.136 0.04776 0.252 0.00096 0.665
10

AC083843.1

 hsa-miR-1299;hsa-miR-143-3p;hsa-miR-154-5p;hsa-miR-193a-3p;hsa-miR-195-5p;hsa-miR-198;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-501-5p;hsa-miR-548c-5p;hsa-miR-551b-5p;hsa-miR-588 14 NFAT5 Sponge network -0.551 0.0041 -0.09 0.53721 0.659
11 RP11-452L6.5 hsa-miR-1299;hsa-miR-143-3p;hsa-miR-154-5p;hsa-miR-15a-5p;hsa-miR-193a-3p;hsa-miR-195-5p;hsa-miR-198;hsa-miR-27a-3p;hsa-miR-539-5p;hsa-miR-551b-5p;hsa-miR-588 11 NFAT5 Sponge network -0.086 0.41405 -0.09 0.53721 0.648
12

AC083843.1

 hsa-miR-193a-3p;hsa-miR-195-3p;hsa-miR-195-5p;hsa-miR-26a-5p;hsa-miR-297;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-501-5p;hsa-miR-548c-5p 10 LRP6 Sponge network -0.551 0.0041 -0.607 0.00016 0.645
13

NEAT1

 hsa-miR-1299;hsa-miR-143-3p;hsa-miR-148a-3p;hsa-miR-15a-5p;hsa-miR-193a-3p;hsa-miR-195-5p;hsa-miR-198;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-501-5p;hsa-miR-588;hsa-miR-605-5p 12 NFAT5 Sponge network -0.872 0.00064 -0.09 0.53721 0.635
14

NEAT1

 hsa-miR-15a-5p;hsa-miR-193a-3p;hsa-miR-195-3p;hsa-miR-195-5p;hsa-miR-26a-5p;hsa-miR-297;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-497-5p;hsa-miR-501-5p 11 LRP6 Sponge network -0.872 0.00064 -0.607 0.00016 0.629
15 AC009120.6 hsa-miR-1299;hsa-miR-143-3p;hsa-miR-154-5p;hsa-miR-190b;hsa-miR-193a-3p;hsa-miR-198;hsa-miR-27a-3p;hsa-miR-29a-3p;hsa-miR-539-5p;hsa-miR-548c-5p 10 NFAT5 Sponge network 0.026 0.81819 -0.09 0.53721 0.582
16 NNT-AS1 hsa-miR-1299;hsa-miR-154-5p;hsa-miR-190b;hsa-miR-193a-3p;hsa-miR-198;hsa-miR-27a-3p;hsa-miR-539-5p;hsa-miR-548c-5p;hsa-miR-551b-5p;hsa-miR-588 10 NFAT5 Sponge network 0.046 0.73141 -0.09 0.53721 0.534
17 PVT1 hsa-miR-15a-5p;hsa-miR-193a-3p;hsa-miR-195-3p;hsa-miR-195-5p;hsa-miR-26a-5p;hsa-miR-297;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-497-5p 10 LRP6 Sponge network -0.229 0.04252 -0.607 0.00016 0.509
18

NEAT1

 hsa-miR-140-5p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-185-3p;hsa-miR-195-5p;hsa-miR-29a-3p;hsa-miR-29c-3p;hsa-miR-324-3p;hsa-miR-342-3p;hsa-miR-497-5p 10 PPARD Sponge network -0.872 0.00064 -0.258 0.01336 0.478
19

NEAT1

 hsa-miR-142-5p;hsa-miR-150-5p;hsa-miR-155-5p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-195-5p;hsa-miR-19b-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-497-5p 11 CCND1 Sponge network -0.872 0.00064 -0.383 0.05738 0.341
20 MIR205HG hsa-miR-142-5p;hsa-miR-150-5p;hsa-miR-155-5p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-195-5p;hsa-miR-19b-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p 10 CCND1 Sponge network -1.268 0 -0.383 0.05738 0.307

Quest ID: 6b1553d00f03aa856863263c75324973