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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-125a-3p CIRBP 1.24 1.0E-5 -0.68 0.00013 miRanda -0.13 2.0E-5 NA
2 hsa-miR-24-3p CIRBP 1 0 -0.68 0.00013 miRNAWalker2 validate -0.28 0 NA
3 hsa-miR-338-5p CIRBP -0.58 0.04722 -0.68 0.00013 MirTarget; PITA; miRNATAP -0.14 0 NA
4 hsa-miR-590-3p CIRBP 2.59 0 -0.68 0.00013 miRanda -0.14 0 NA
5 hsa-miR-590-5p CIRBP 3.18 0 -0.68 0.00013 miRanda -0.1 0.00028 NA
6 hsa-miR-629-3p CIRBP 2.37 0 -0.68 0.00013 mirMAP -0.17 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 RNA PROCESSING 61 835 1.087e-33 5.06e-30
2 MRNA METABOLIC PROCESS 53 611 8.454e-33 1.967e-29
3 MRNA PROCESSING 46 432 2.552e-32 3.958e-29
4 RNA SPLICING VIA TRANSESTERIFICATION REACTIONS 38 267 1.89e-31 2.199e-28
5 RNA SPLICING 42 367 8.866e-31 8.25e-28
6 RIBONUCLEOPROTEIN COMPLEX BIOGENESIS 29 440 7.001e-15 5.43e-12
7 NLS BEARING PROTEIN IMPORT INTO NUCLEUS 9 22 7.767e-13 5.163e-10
8 MITOTIC CELL CYCLE 34 766 2.608e-12 1.517e-09
9 CELL CYCLE 45 1316 4.275e-12 2.21e-09
10 CELL CYCLE PHASE TRANSITION 20 255 5.853e-12 2.723e-09
11 NUCLEAR IMPORT 15 129 1.052e-11 4.449e-09
12 REGULATION OF CELL CYCLE 37 949 1.152e-11 4.467e-09
13 CELL CYCLE G1 S PHASE TRANSITION 14 111 1.711e-11 5.688e-09
14 G1 S TRANSITION OF MITOTIC CELL CYCLE 14 111 1.711e-11 5.688e-09
15 POSITIVE REGULATION OF GENE EXPRESSION 51 1733 3.138e-11 9.127e-09
16 CELL CYCLE PROCESS 39 1081 3.057e-11 9.127e-09
17 NUCLEAR TRANSPORT 22 355 5.115e-11 1.4e-08
18 REGULATION OF TELOMERASE RNA LOCALIZATION TO CAJAL BODY 7 15 9.605e-11 2.352e-08
19 POSITIVE REGULATION OF TELOMERASE RNA LOCALIZATION TO CAJAL BODY 7 15 9.605e-11 2.352e-08
20 PROTEIN IMPORT 15 155 1.493e-10 3.475e-08
21 PROTEIN LOCALIZATION TO NUCLEUS 15 156 1.637e-10 3.626e-08
22 PROTEIN FOLDING 17 224 4.013e-10 8.487e-08
23 POSTTRANSCRIPTIONAL REGULATION OF GENE EXPRESSION 23 448 7.52e-10 1.521e-07
24 REGULATION OF MRNA METABOLIC PROCESS 12 118 6.103e-09 1.183e-06
25 CELL DIVISION 22 460 6.595e-09 1.227e-06
26 REGULATION OF DNA REPLICATION 13 161 2.342e-08 4.192e-06
27 RIBONUCLEOPROTEIN COMPLEX SUBUNIT ORGANIZATION 14 199 3.863e-08 6.657e-06
28 PROTEIN LOCALIZATION TO ORGANELLE 23 556 4.347e-08 7.224e-06
29 RIBOSOME BIOGENESIS 17 308 4.809e-08 7.499e-06
30 MULTI ORGANISM TRANSPORT 9 68 4.996e-08 7.499e-06
31 MULTI ORGANISM LOCALIZATION 9 68 4.996e-08 7.499e-06
32 POSITIVE REGULATION OF TELOMERE MAINTENANCE VIA TELOMERE LENGTHENING 7 33 5.402e-08 7.854e-06
33 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO CHROMOSOME 5 11 6.291e-08 8.236e-06
34 INTERSPECIES INTERACTION BETWEEN ORGANISMS 25 662 6.372e-08 8.236e-06
35 REGULATION OF TELOMERE MAINTENANCE VIA TELOMERE LENGTHENING 8 50 6.126e-08 8.236e-06
36 SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM 25 662 6.372e-08 8.236e-06
37 MITOTIC NUCLEAR DIVISION 18 361 8.944e-08 1.125e-05
38 SPLICEOSOMAL COMPLEX ASSEMBLY 8 53 9.835e-08 1.204e-05
39 RNA LOCALIZATION 13 185 1.213e-07 1.447e-05
40 RRNA METABOLIC PROCESS 15 255 1.333e-07 1.513e-05
41 MACROMOLECULAR COMPLEX ASSEMBLY 38 1398 1.323e-07 1.513e-05
42 REGULATION OF DNA METABOLIC PROCESS 17 340 1.986e-07 2.201e-05
43 DNA METABOLIC PROCESS 26 758 2.246e-07 2.43e-05
44 DNA GEOMETRIC CHANGE 9 81 2.341e-07 2.476e-05
45 REGULATION OF PROTEIN LOCALIZATION TO CHROMOSOME TELOMERIC REGION 5 14 2.655e-07 2.745e-05
46 CELL CYCLE G2 M PHASE TRANSITION 11 138 3.282e-07 3.32e-05
47 REGULATION OF RNA STABILITY 11 139 3.531e-07 3.496e-05
48 POSITIVE REGULATION OF DNA REPLICATION 9 86 3.938e-07 3.818e-05
49 RNA SECONDARY STRUCTURE UNWINDING 7 44 4.379e-07 4.158e-05
50 ESTABLISHMENT OF PROTEIN LOCALIZATION TO ORGANELLE 17 361 4.613e-07 4.287e-05
51 MODULATION BY SYMBIONT OF HOST CELLULAR PROCESS 6 28 4.699e-07 4.287e-05
52 REGULATION OF TELOMERE MAINTENANCE 8 67 6.354e-07 5.686e-05
53 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 43 1805 6.669e-07 5.855e-05
54 POSITIVE REGULATION OF TELOMERE MAINTENANCE 7 47 6.991e-07 6.024e-05
55 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 31 1087 8.138e-07 6.885e-05
56 MACROMOLECULE CATABOLIC PROCESS 28 926 9.438e-07 7.842e-05
57 REGULATION OF RNA SPLICING 9 97 1.104e-06 9.013e-05
58 CELLULAR RESPONSE TO DNA DAMAGE STIMULUS 24 720 1.126e-06 9.032e-05
59 NCRNA PROCESSING 17 386 1.163e-06 9.175e-05
60 RNA 3 END PROCESSING 9 98 1.204e-06 9.34e-05
61 REGULATION OF TRANSFERASE ACTIVITY 28 946 1.433e-06 0.0001076
62 SEXUAL REPRODUCTION 24 730 1.433e-06 0.0001076
63 REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 16 354 1.734e-06 0.000128
64 ORGANELLE FISSION 19 496 2.154e-06 0.0001566
65 REGULATION OF CHROMOSOME ORGANIZATION 14 278 2.247e-06 0.0001609
66 PROTEIN TARGETING 17 406 2.31e-06 0.0001629
67 MODULATION BY VIRUS OF HOST MORPHOLOGY OR PHYSIOLOGY 6 37 2.673e-06 0.0001856
68 POSITIVE REGULATION OF DNA BIOSYNTHETIC PROCESS 7 59 3.396e-06 0.000232
69 MULTICELLULAR ORGANISM REPRODUCTION 24 768 3.44e-06 0.000232
70 REPRODUCTION 33 1297 4.184e-06 0.0002781
71 MULTI ORGANISM REPRODUCTIVE PROCESS 26 891 4.544e-06 0.0002978
72 REGULATION OF MRNA SPLICING VIA SPLICEOSOME 7 62 4.763e-06 0.0003078
73 CHROMOSOME ORGANIZATION 28 1009 4.924e-06 0.0003138
74 NEGATIVE REGULATION OF CELL CYCLE 17 433 5.451e-06 0.0003427
75 POSITIVE REGULATION OF CHROMOSOME ORGANIZATION 10 150 5.733e-06 0.0003557
76 NCRNA METABOLIC PROCESS 19 533 6.086e-06 0.0003726
77 POSITIVE REGULATION OF RNA SPLICING 5 25 6.392e-06 0.0003862
78 RESPONSE TO ORGANIC CYCLIC COMPOUND 26 917 7.578e-06 0.0004521
79 REGULATION OF DNA BIOSYNTHETIC PROCESS 8 94 8.441e-06 0.0004971
80 POSITIVE REGULATION OF MRNA METABOLIC PROCESS 6 45 8.711e-06 0.0005004
81 MODIFICATION BY SYMBIONT OF HOST MORPHOLOGY OR PHYSIOLOGY 6 45 8.711e-06 0.0005004
82 CELL CYCLE CHECKPOINT 11 194 9.242e-06 0.0005244
83 REGULATION OF CELLULAR PROTEIN LOCALIZATION 19 552 9.989e-06 0.00056
84 POSITIVE REGULATION OF TELOMERASE ACTIVITY 5 28 1.151e-05 0.0006357
85 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 9 129 1.174e-05 0.0006357
86 NUCLEOBASE CONTAINING COMPOUND TRANSPORT 11 199 1.175e-05 0.0006357
87 PROTEIN PHOSPHORYLATION 26 944 1.26e-05 0.0006737
88 MRNA 3 END PROCESSING 7 72 1.302e-05 0.0006883
89 NEGATIVE REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 9 131 1.329e-05 0.0006948
90 RNA POLYADENYLATION 5 29 1.379e-05 0.000713
91 REGULATION OF PROTEIN LOCALIZATION 26 950 1.406e-05 0.0007189
92 DNA TEMPLATED TRANSCRIPTION TERMINATION 8 101 1.436e-05 0.0007263
93 CELLULAR MACROMOLECULAR COMPLEX ASSEMBLY 22 727 1.484e-05 0.0007423
94 RNA STABILIZATION 5 31 1.939e-05 0.0009596
95 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 23 799 2.078e-05 0.001018
96 POSITIVE REGULATION OF MRNA PROCESSING 5 32 2.277e-05 0.001093
97 NUCLEIC ACID PHOSPHODIESTER BOND HYDROLYSIS 12 254 2.278e-05 0.001093
98 DNA INTEGRITY CHECKPOINT 9 146 3.157e-05 0.001499
99 CELLULAR RESPONSE TO STRESS 35 1565 3.323e-05 0.001562
100 PEPTIDYL SERINE MODIFICATION 9 148 3.514e-05 0.001619
101 CELLULAR RESPONSE TO HORMONE STIMULUS 18 552 3.512e-05 0.001619
102 CELLULAR RESPONSE TO LIPID 16 457 4.181e-05 0.001889
103 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 14 360 4.149e-05 0.001889
104 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 19 616 4.506e-05 0.002016
105 CELLULAR COMPONENT DISASSEMBLY 17 515 5.006e-05 0.002218
106 REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 12 280 5.88e-05 0.002557
107 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 16 470 5.829e-05 0.002557
108 CELLULAR MACROMOLECULE LOCALIZATION 29 1234 7.192e-05 0.003099
109 ANDROGEN RECEPTOR SIGNALING PATHWAY 5 41 7.829e-05 0.003342
110 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 38 1848 8.962e-05 0.003785
111 REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 7 97 9.03e-05 0.003785
112 GAMETE GENERATION 18 595 9.178e-05 0.003813
113 INTRACELLULAR RECEPTOR SIGNALING PATHWAY 9 168 9.405e-05 0.003873
114 REGULATION OF TELOMERASE ACTIVITY 5 43 9.881e-05 0.004033
115 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 25 1008 0.0001024 0.004142
116 MODIFICATION OF MORPHOLOGY OR PHYSIOLOGY OF OTHER ORGANISM 7 100 0.0001095 0.004391
117 NUCLEUS ORGANIZATION 8 136 0.000121 0.004812
118 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 20 724 0.0001284 0.005064
119 NEGATIVE REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 8 139 0.0001408 0.005458
120 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 10 218 0.0001403 0.005458
121 MEMBRANE DISASSEMBLY 5 47 0.000152 0.005798
122 NUCLEAR ENVELOPE DISASSEMBLY 5 47 0.000152 0.005798
123 REGULATION OF PROTEIN STABILITY 10 221 0.0001568 0.005933
124 MRNA SPLICE SITE SELECTION 4 26 0.0001671 0.006219
125 REGULATION OF CELLULAR SENESCENCE 4 26 0.0001671 0.006219
126 REGULATION OF CELLULAR RESPONSE TO HEAT 6 76 0.0001768 0.00653
127 POSITIVE REGULATION OF DNA METABOLIC PROCESS 9 185 0.0001951 0.006941
128 MICROTUBULE BASED PROCESS 16 522 0.0001954 0.006941
129 DNA CATABOLIC PROCESS 4 27 0.0001945 0.006941
130 PROTEASOMAL PROTEIN CATABOLIC PROCESS 11 271 0.0001921 0.006941
131 RNA CATABOLIC PROCESS 10 227 0.0001949 0.006941
132 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 20 750 0.0002048 0.007165
133 DNA CONFORMATION CHANGE 11 273 0.0002048 0.007165
134 NUCLEAR EXPORT 8 147 0.0002069 0.007185
135 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 32 1517 0.0002207 0.007515
136 RESPONSE TO ENDOGENOUS STIMULUS 31 1450 0.0002211 0.007515
137 NEGATIVE REGULATION OF PHOSPHORYLATION 14 422 0.0002213 0.007515
138 CELLULAR CATABOLIC PROCESS 29 1322 0.0002346 0.007911
139 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 24 1004 0.0002455 0.008218
140 PROTEIN COMPLEX SUBUNIT ORGANIZATION 32 1527 0.0002481 0.008247
141 DNA REPAIR 15 480 0.000252 0.008317
142 PROTEIN IMPORT INTO NUCLEUS TRANSLOCATION 4 29 0.0002588 0.008479
143 REGULATION OF BINDING 11 283 0.0002789 0.009075
144 MALE GAMETE GENERATION 15 486 0.0002876 0.009294
145 NEGATIVE REGULATION OF MOLECULAR FUNCTION 25 1079 0.0002908 0.009331
NumGOOverlapSizeP ValueAdj. P Value
1 RNA BINDING 98 1598 6.817e-50 6.333e-47
2 POLY A RNA BINDING 84 1170 4.236e-47 1.968e-44
3 RIBONUCLEOTIDE BINDING 70 1860 2.319e-21 7.182e-19
4 ADENYL NUCLEOTIDE BINDING 61 1514 6.918e-20 1.607e-17
5 NUCLEAR LOCALIZATION SEQUENCE BINDING 9 21 4.633e-13 8.608e-11
6 RNA HELICASE ACTIVITY 12 67 6.965e-12 1.078e-09
7 HELICASE ACTIVITY 16 153 1.093e-11 1.451e-09
8 HYDROLASE ACTIVITY ACTING ON ACID ANHYDRIDES 34 820 1.688e-11 1.961e-09
9 PURINE NTP DEPENDENT HELICASE ACTIVITY 13 98 4.807e-11 4.962e-09
10 CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 9 34 7.317e-11 6.797e-09
11 SIGNAL SEQUENCE BINDING 9 39 2.82e-10 2.382e-08
12 POLY PURINE TRACT BINDING 7 19 7.248e-10 5.612e-08
13 SINGLE STRANDED RNA BINDING 10 69 3.575e-09 2.555e-07
14 PROTEIN SERINE THREONINE KINASE ACTIVITY 21 445 1.869e-08 1.24e-06
15 HEAT SHOCK PROTEIN BINDING 10 89 4.427e-08 2.723e-06
16 ATPASE ACTIVITY 20 427 4.689e-08 2.723e-06
17 ATPASE ACTIVITY COUPLED 17 313 6.074e-08 3.319e-06
18 MRNA BINDING 12 155 1.306e-07 6.74e-06
19 PROTEIN TRANSPORTER ACTIVITY 9 99 1.313e-06 6.418e-05
20 CYCLIN BINDING 5 19 1.475e-06 6.852e-05
21 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 28 992 3.571e-06 0.000158
22 ENZYME BINDING 40 1737 4.08e-06 0.0001723
23 PROTEIN KINASE ACTIVITY 21 640 6.975e-06 0.0002817
24 MACROMOLECULAR COMPLEX BINDING 34 1399 7.872e-06 0.0003047
25 UNFOLDED PROTEIN BINDING 8 100 1.335e-05 0.000496
26 DNA HELICASE ACTIVITY 6 53 2.284e-05 0.0008161
27 TRANSCRIPTION FACTOR BINDING 17 524 6.197e-05 0.002132
28 SINGLE STRANDED DNA BINDING 7 93 6.907e-05 0.002213
29 DOUBLE STRANDED RNA BINDING 6 64 6.756e-05 0.002213
30 GTPASE ACTIVITY 11 246 8.207e-05 0.002542
31 KINASE ACTIVITY 22 842 0.0001309 0.003924
32 MRNA 3 UTR BINDING 5 48 0.0001682 0.004883
33 HSP90 PROTEIN BINDING 4 27 0.0001945 0.005475
34 CHROMATIN BINDING 14 435 0.0003011 0.008227
35 POLY A BINDING 3 13 0.0003325 0.008825
NumGOOverlapSizeP ValueAdj. P Value
1 RIBONUCLEOPROTEIN COMPLEX 52 721 2.891e-28 1.688e-25
2 SPLICEOSOMAL COMPLEX 26 172 2.071e-22 6.049e-20
3 CATALYTIC STEP 2 SPLICEOSOME 17 89 8.098e-17 1.576e-14
4 NUCLEOLUS 41 848 5.561e-16 8.119e-14
5 NUCLEAR BODY 21 349 2.47e-10 2.885e-08
6 NUCLEAR PORE 11 77 6.793e-10 6.612e-08
7 RIBONUCLEOPROTEIN GRANULE 14 148 8.42e-10 7.024e-08
8 MICROTUBULE CYTOSKELETON 34 1068 1.59e-08 1.031e-06
9 NUCLEOPLASM PART 27 708 1.477e-08 1.031e-06
10 NUCLEAR SPECK 14 194 2.802e-08 1.637e-06
11 NUCLEAR ENVELOPE 18 416 7.202e-07 3.824e-05
12 CYCLIN DEPENDENT PROTEIN KINASE HOLOENZYME COMPLEX 6 31 8.937e-07 4.349e-05
13 CYTOPLASMIC STRESS GRANULE 6 32 1.09e-06 4.897e-05
14 CYTOSKELETAL PART 36 1436 2.013e-06 8.398e-05
15 CHROMOSOME 26 880 3.635e-06 0.0001391
16 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPLEX 7 60 3.81e-06 0.0001391
17 MICROTUBULE ORGANIZING CENTER 21 623 4.618e-06 0.0001586
18 PRP19 COMPLEX 4 13 8.926e-06 0.0002744
19 CHROMATOID BODY 4 13 8.926e-06 0.0002744
20 SPINDLE 13 289 1.744e-05 0.0005092
21 CAJAL BODY 6 52 2.044e-05 0.0005684
22 CENTROSOME 17 487 2.489e-05 0.0006607
23 CYTOSKELETON 41 1967 3.286e-05 0.0008344
24 PROTEIN KINASE COMPLEX 7 90 5.599e-05 0.001362
25 SPINDLE POLE 8 126 7.082e-05 0.001654
26 CHROMATIN 15 441 0.0001004 0.002256
27 MICROTUBULE 14 405 0.0001449 0.003133
28 NUCLEAR CHROMOSOME 16 523 0.0001997 0.004021
29 ENDOPLASMIC RETICULUM CHAPERONE COMPLEX 3 11 0.0001949 0.004021
30 TRANSFERASE COMPLEX 19 703 0.0002503 0.004873
31 U2 TYPE SPLICEOSOMAL COMPLEX 4 31 0.000337 0.006349
32 NUCLEAR PERIPHERY 7 121 0.0003566 0.006507
33 NUCLEAR CYCLIN DEPENDENT PROTEIN KINASE HOLOENZYME COMPLEX 3 15 0.0005205 0.009212

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Cell_cycle_hsa04110 12 124 1.076e-08 5.595e-07
2 Oocyte_meiosis_hsa04114 9 124 8.516e-06 0.0002214
3 Gap_junction_hsa04540 7 88 4.845e-05 0.0008397
4 Cellular_senescence_hsa04218 9 160 6.459e-05 0.0008397
5 FoxO_signaling_pathway_hsa04068 8 132 9.823e-05 0.001022
6 Adherens_junction_hsa04520 6 72 0.000131 0.001135
7 p53_signaling_pathway_hsa04115 5 68 0.0008592 0.006383
8 Wnt_signaling_pathway_hsa04310 6 146 0.005249 0.03412
9 PI3K_Akt_signaling_pathway_hsa04151 9 352 0.01501 0.08674
10 Apoptosis_hsa04210 5 138 0.01742 0.09057
11 Phagosome_hsa04145 5 152 0.02522 0.1148
12 Hippo_signaling_pathway_hsa04390 5 154 0.02649 0.1148
13 Tight_junction_hsa04530 5 170 0.03812 0.1458
14 Hippo_signaling_pathway_multiple_species_hsa04392 2 29 0.03927 0.1458
15 TGF_beta_signaling_pathway_hsa04350 3 84 0.06337 0.2137
16 Focal_adhesion_hsa04510 5 199 0.06614 0.2137
17 Ferroptosis_hsa04216 2 40 0.06986 0.2137
18 Regulation_of_actin_cytoskeleton_hsa04810 5 208 0.07667 0.2215
19 Hedgehog_signaling_pathway_hsa04340 2 47 0.09223 0.2431
20 HIF_1_signaling_pathway_hsa04066 3 100 0.09512 0.2431
21 cGMP_PKG_signaling_pathway_hsa04022 4 163 0.1018 0.2431
22 MAPK_signaling_pathway_hsa04010 6 295 0.1028 0.2431
23 VEGF_signaling_pathway_hsa04370 2 59 0.1344 0.3039
24 mTOR_signaling_pathway_hsa04150 3 151 0.2257 0.489
25 NF_kappa_B_signaling_pathway_hsa04064 2 95 0.2756 0.5733
26 TNF_signaling_pathway_hsa04668 2 108 0.3277 0.6553
27 Rap1_signaling_pathway_hsa04015 3 206 0.3873 0.746
28 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 2 139 0.4464 0.8005
29 Endocytosis_hsa04144 3 244 0.4953 0.8529
30 Calcium_signaling_pathway_hsa04020 2 182 0.5898 0.9255

Quest ID: 70dcf9f3400e6f566c0008b0c409a832