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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-let-7a-5p AIFM1 -1.37 0 0.7 0 TargetScan; miRNATAP -0.11 0.00018 NA
2 hsa-let-7b-5p AIFM1 -1.62 0 0.7 0 miRNATAP -0.12 0 NA
3 hsa-let-7a-5p AKT2 -1.37 0 0.16 0.1135 TargetScan -0.12 0 NA
4 hsa-miR-29a-3p AKT2 0.1 0.5732 0.16 0.1135 MirTarget -0.1 4.0E-5 24076586 Furthermore a feed-back loop comprising of c-Myc miR-29 family and Akt2 were found in myeloid leukemogenesis
5 hsa-miR-106b-5p AKT3 1.47 0 -1.44 0 miRNATAP -0.16 0.00426 NA
6 hsa-miR-107 AKT3 0.66 0 -1.44 0 PITA; miRanda -0.26 0.0031 NA
7 hsa-miR-146b-5p AKT3 1.09 1.0E-5 -1.44 0 miRNAWalker2 validate -0.15 0.00189 NA
8 hsa-miR-15a-5p AKT3 1.63 0 -1.44 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.41 0 NA
9 hsa-miR-16-5p AKT3 0.75 0 -1.44 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.27 0.0001 NA
10 hsa-miR-17-3p AKT3 1.37 0 -1.44 0 miRNATAP -0.15 0.01027 NA
11 hsa-miR-17-5p AKT3 2.07 0 -1.44 0 TargetScan; miRNATAP -0.22 0 NA
12 hsa-miR-181a-5p AKT3 -0.38 0.05621 -1.44 0 miRNATAP -0.23 9.0E-5 NA
13 hsa-miR-181b-5p AKT3 0.67 0.00024 -1.44 0 miRNATAP -0.37 0 NA
14 hsa-miR-20a-5p AKT3 2.65 0 -1.44 0 miRNATAP -0.24 0 NA
15 hsa-miR-22-3p AKT3 1.43 0 -1.44 0 miRNATAP -0.26 0.00109 NA
16 hsa-miR-28-3p AKT3 0.39 0.00778 -1.44 0 miRNATAP -0.2 0.01226 NA
17 hsa-miR-29a-3p AKT3 0.1 0.5732 -1.44 0 miRNATAP -0.15 0.02016 NA
18 hsa-miR-29b-2-5p AKT3 0.35 0.19484 -1.44 0 mirMAP -0.18 2.0E-5 NA
19 hsa-miR-29b-3p AKT3 3.11 0 -1.44 0 miRNATAP -0.27 0 26512921 MicroRNA 29B mir 29b regulates the Warburg effect in ovarian cancer by targeting AKT2 and AKT3
20 hsa-miR-3065-5p AKT3 0.65 0.09995 -1.44 0 mirMAP -0.18 0 NA
21 hsa-miR-335-3p AKT3 1.51 0 -1.44 0 mirMAP -0.13 0.01067 NA
22 hsa-miR-362-5p AKT3 0.66 0.02433 -1.44 0 PITA; TargetScan; miRNATAP -0.23 0 NA
23 hsa-miR-542-3p AKT3 1.62 0 -1.44 0 miRanda -0.19 1.0E-5 NA
24 hsa-miR-93-5p AKT3 1.51 0 -1.44 0 miRNATAP -0.25 0 NA
25 hsa-miR-23a-3p APAF1 0.11 0.39309 0.05 0.6283 miRNATAP -0.13 0.00069 24992592; 24249161 Luciferase assay was performed to verify a putative target site of miR-23a in the 3'-UTR of apoptosis protease activating factor 1 APAF1 mRNA; The expression levels of miR-23a and APAF1 in CRC cell lines SW480 and SW620 and clinical samples were assessed using reverse transcription-quantitative real-time PCR RT-qPCR and Western blot; Moreover miR-23a up-regulation was coupled with APAF1 down-regulation in CRC tissue samples;We found that the expression of miR-23a was increased and the level of apoptosis-activating factor-1 APAF-1 was decreased in 5-FU-treated colon cancer cells compared to untreated cells; APAF-1 as a target gene of miR-23a was identified and miR-23a antisense-induced increase in the activation of caspase-9 was observed
26 hsa-miR-23b-3p APAF1 -0.07 0.62059 0.05 0.6283 miRNATAP -0.11 0.00216 NA
27 hsa-miR-27a-3p APAF1 0.43 0.00737 0.05 0.6283 miRNATAP -0.16 0 NA
28 hsa-miR-27b-3p APAF1 0.24 0.12264 0.05 0.6283 miRNATAP -0.17 0 NA
29 hsa-miR-664a-3p APAF1 0.44 0.02142 0.05 0.6283 mirMAP -0.11 2.0E-5 NA
30 hsa-miR-15a-5p BCL2 1.63 0 -0.49 0.06421 miRNAWalker2 validate; miRTarBase -0.19 0.00401 26915294; 25594541; 18931683; 25623762; 22335947 As a result transcript levels of the tumor-suppressive miR-15 and let-7 families increased which targeted and decreased the expression of the crucial prosurvival genes BCL-2 and BCL-XL respectively;MicroRNAs miRNAs encoded by the miR-15 cluster are known to induce G1 arrest and apoptosis by targeting G1 checkpoints and the anti-apoptotic B cell lymphoma 2 BCL-2 gene;MicroRNAs miRNAs are noncoding small RNAs that repress protein translation by targeting specific messenger RNAs miR-15a and miR-16-1 act as putative tumor suppressors by targeting the oncogene BCL2;miR 15a and miR 16 modulate drug resistance by targeting bcl 2 in human colon cancer cells; To investigate the reversal effect of targeted modulation of bcl-2 expression by miR-15a and miR-16 on drug resistance of human colon cancer cells;The expression of MiR-15a was significantly inhibited by Bcl-2 P < 0.05
31 hsa-miR-17-5p BCL2 2.07 0 -0.49 0.06421 miRNAWalker2 validate; miRTarBase -0.12 0.02174 25435430 Combined overexpression of miR-16 and miR-17 greatly reduced Beclin-1 and Bcl-2 expressions respectively; miR-17 overexpression reduced cytoprotective autophagy by targeting Beclin-1 whereas overexpression of miR-16 potentiated paclitaxel induced apoptotic cell death by inhibiting anti-apoptotic protein Bcl-2
32 hsa-miR-200c-3p BCL2 0.38 0.08422 -0.49 0.06421 miRNAWalker2 validate; miRTarBase; mirMAP -0.13 0.02205 NA
33 hsa-miR-20a-3p BCL2 2.52 0 -0.49 0.06421 mirMAP -0.1 0.01974 NA
34 hsa-miR-20a-5p BCL2 2.65 0 -0.49 0.06421 miRNAWalker2 validate; miRTarBase -0.12 0.01368 NA
35 hsa-miR-21-5p BCL2 4.38 0 -0.49 0.06421 miRNAWalker2 validate; miRTarBase -0.2 1.0E-5 22964582; 21468550; 25994220; 25381586; 26555418; 23359184; 21376256 Tumors harvested from these lungs have elevated levels of oncogenic miRNAs miR-21 and miR-155; are deficient for p53-regulated miRNAs; and have heightened expression of miR-34 target genes such as Met and Bcl-2;BCL-2 up-regulation could be achieved by miR-21 overexpression which prevented T24 cells from apoptosis induced by doxorubicin; Furthermore the miR-21 induced BCL-2 up-regulation could be cancelled by the PI3K inhibitor LY294002;Meanwhile miR-21 loss reduced STAT3 and Bcl-2 activation causing an increase in the apoptosis of tumour cells in CAC mice;Changes in the sensitivity of osteosarcoma cells to CDDP were examined after transfection with miR-21 mimics or anti-miR-21 or bcl-2 siRNA in combination with CDDP;The expression of Bax Bcl-2 and miR-21 in parental and paclitaxel-resistant cells was detected by RT-PCR and Western blotting;Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR 21 regulation of BCL 2 expression; We also used Western blot to measure BCL-2 protein levels after down-regulation of miR-21 expression; Besides down-regulation of miR-21 expression can inhibit BCL-2 expression in PANC-1 CFPAC-1 and MIA Paca-2 cells; Over-expression of miR-21 expression can reverse down-regulation of BCL-2 expression and apoptosis induced by resveratrol; In this study we demonstrated that the effect of resveratrol on apoptosis is due to inhibiting miR-21 regulation of BCL-2 expression;Bcl 2 upregulation induced by miR 21 via a direct interaction is associated with apoptosis and chemoresistance in MIA PaCa 2 pancreatic cancer cells; However the roles and mechanisms of miRNA miR-21 in regulation of Bcl-2 in pancreatic cancer remain to be elucidated; Then luciferase activity was observed after miR-21 mimics and pRL-TK plasmids containing wild-type and mutant 3'UTRs of Bcl-2 mRNA were co-transfected; Cells transfected with miR-21 inhibitor revealed an opposite trend. There was a significant increase in luciferase activity in the cells transfected with the wild-type pRL-TK plasmid in contrast to those transfected with the mutant one indicating that miR-21 promotes Bcl-2 expression by binding directly to the 3'UTR of Bcl-2 mRNA; Upregulation of Bcl-2 directly induced by miR-21 is associated with apoptosis chemoresistance and proliferation of MIA PaCa-2 pancreatic cancer cells
36 hsa-miR-224-5p BCL2 1.92 0 -0.49 0.06421 mirMAP -0.14 0 24796455 In addition the expressions of Bcl2 mRNA and protein were 1.05 ± 0.04 and 0.21 ± 0.03 in the miR-224 ASO group significantly lower than that in the control group 4.87 ± 0.96 and 0.88 ± 0.09 P < 0.01
37 hsa-miR-24-2-5p BCL2 1.44 0 -0.49 0.06421 miRNAWalker2 validate; miRTarBase -0.16 0.00352 NA
38 hsa-miR-29a-5p BCL2 1.9 0 -0.49 0.06421 mirMAP -0.24 0 20041405 Subsequent investigation characterized two antiapoptotic molecules Bcl-2 and Mcl-1 as direct targets of miR-29; Furthermore silencing of Bcl-2 and Mcl-1 phenocopied the proapoptotic effect of miR-29 whereas overexpression of these proteins attenuated the effect of miR-29
39 hsa-miR-3065-5p BCL2 0.65 0.09995 -0.49 0.06421 mirMAP -0.12 0.00023 NA
40 hsa-miR-34a-5p BCL2 1.41 0 -0.49 0.06421 miRNAWalker2 validate; miRTarBase -0.19 0.00135 22964582; 24565525; 23155233; 24444609; 20687223; 22623155; 24988056; 18803879; 19714243; 25053345; 20433755; 21399894; 23862748 Tumors harvested from these lungs have elevated levels of oncogenic miRNAs miR-21 and miR-155; are deficient for p53-regulated miRNAs; and have heightened expression of miR-34 target genes such as Met and Bcl-2;In vitro and in vivo experiments showed that miR-34a and DOX can be efficiently encapsulated into HA-CS NPs and delivered into tumor cells or tumor tissues and enhance anti-tumor effects of DOX by suppressing the expression of non-pump resistance and anti-apoptosis proto-oncogene Bcl-2;The miR-34a expression levels in cells after irradiation at 30 and 60 Gy were 0.17- and 18.7-times the BCL2 and caspase-9 expression levels respectively;Functional analyses further indicate that restoration of miR-34a inhibits B cell lymphoma-2 Bcl-2 protein expression to withdraw the survival advantage of these resistant NSCLC cells;Thus in PC3PR cells reduced expression of miR-34a confers paclitaxel resistance via up-regulating SIRT1 and Bcl2 expression; MiR-34a and its downstream targets SIRT1 and Bcl2 play important roles in the development of paclitaxel resistance all of which can be useful biomarkers and promising therapeutic targets for the drug resistance in hormone-refractory prostate cancer;MiR 34a inhibits proliferation and migration of breast cancer through down regulation of Bcl 2 and SIRT1; In this study we aimed to determine the effect of miR-34a on the growth of breast cancer and to investigate whether its effect is achieved by targeting Bcl-2 and SIRT1; Bcl-2 and SIRT1 as the targets of miR-34a were found to be in reverse correlation with ectopic expression of miR-34a;Target analysis indicated that micro RNA miR-34a directly regulates Bcl-2 and miR-34a overexpression decreased Bcl-2 protein level in gastric cancer cells; We also found that luteolin upregulates miR-34a expression and downregulates Bcl-2 expression; Based on these results we can draw the conclusion that luteolin partly decreases Bcl-2 expression through upregulating miR-34a expression;miR-34 targets Notch HMGA2 and Bcl-2 genes involved in the self-renewal and survival of cancer stem cells; Human gastric cancer cells were transfected with miR-34 mimics or infected with the lentiviral miR-34-MIF expression system and validated by miR-34 reporter assay using Bcl-2 3'UTR reporter; Human gastric cancer Kato III cells with miR-34 restoration reduced the expression of target genes Bcl-2 Notch and HMGA2; Bcl-2 3'UTR reporter assay showed that the transfected miR-34s were functional and confirmed that Bcl-2 is a direct target of miR-34; The mechanism of miR-34-mediated suppression of self-renewal appears to be related to the direct modulation of downstream targets Bcl-2 Notch and HMGA2 indicating that miR-34 may be involved in gastric cancer stem cell self-renewal/differentiation decision-making;Among the target proteins regulated by miR-34 are Notch pathway proteins and Bcl-2 suggesting the possibility of a role for miR-34 in the maintenance and survival of cancer stem cells; Our data support the view that miR-34 may be involved in pancreatic cancer stem cell self-renewal potentially via the direct modulation of downstream targets Bcl-2 and Notch implying that miR-34 may play an important role in pancreatic cancer stem cell self-renewal and/or cell fate determination;Manipulating miR-34a in prostate cancer cells confirms that this miRNA regulates BCL-2 and may in part regulate response to docetaxel;For instance miR-34a up-regulation corresponded with a down-regulation of BCL2 protein; Treating Par-4-overexpressing HT29 cells with a miR-34a antagomir functionally reversed both BCL2 down-regulation and apoptosis by 5-FU;Quantitative PCR and western analysis confirmed decreased expression of two genes BCL-2 and CCND1 in docetaxel-resistant cells which are both targeted by miR-34a;MicroRNA 34a targets Bcl 2 and sensitizes human hepatocellular carcinoma cells to sorafenib treatment; HCC tissues with lower miR-34a expression displayed higher expression of Bcl-2 protein than those with high expression of miR-34a; therefore an inverse correlation is evident between the miR-34a level and Bcl-2 expression; Bioinformatics and luciferase reporter assays revealed that miR-34a binds the 3'-UTR of the Bcl-2 mRNA and represses its translation; Western blotting analysis and qRT-PCR confirmed that Bcl-2 is inhibited by miR-34a overexpression; Functional analyses indicated that the restoration of miR-34a reduced cell viability promoted cell apoptosis and potentiated sorafenib-induced apoptosis and toxicity in HCC cell lines by inhibiting Bcl-2 expression
41 hsa-miR-365a-3p BCL2 0.01 0.9536 -0.49 0.06421 miRNAWalker2 validate; miRTarBase -0.14 0.01107 NA
42 hsa-miR-450b-5p BCL2 1.69 0 -0.49 0.06421 mirMAP -0.2 0 NA
43 hsa-miR-452-5p BCL2 0.64 0.04582 -0.49 0.06421 mirMAP -0.12 0.00113 NA
44 hsa-miR-542-3p BCL2 1.62 0 -0.49 0.06421 mirMAP -0.19 3.0E-5 NA
45 hsa-miR-590-3p BCL2 0.84 0.00129 -0.49 0.06421 miRanda; mirMAP -0.12 0.02705 NA
46 hsa-miR-590-5p BCL2 2.07 0 -0.49 0.06421 miRanda -0.18 0.00054 NA
47 hsa-miR-96-5p BCL2 3.04 0 -0.49 0.06421 miRNAWalker2 validate; TargetScan -0.14 0.00193 NA
48 hsa-miR-500a-5p BIRC2 0.65 0.01047 -0.06 0.62026 MirTarget -0.11 0 NA
49 hsa-miR-24-1-5p BIRC3 0.86 0.00011 0.13 0.67648 MirTarget -0.21 0.00165 NA
50 hsa-miR-375 BIRC3 0.62 0.1492 0.13 0.67648 miRNAWalker2 validate -0.2 0 23726271 Taken together these data suggest that miR-375 sensitizes TNF-α-induced apoptosis and the reduction in the expression of the apoptosis inhibitory proteins cFLIP-L and cIAP2 plays an important role in this sensitization
51 hsa-miR-664a-3p BIRC3 0.44 0.02142 0.13 0.67648 mirMAP -0.17 0.0216 NA
52 hsa-miR-98-5p BIRC3 1.17 0 0.13 0.67648 miRNAWalker2 validate -0.14 0.0476 NA
53 hsa-miR-107 CAPN2 0.66 0 -0.31 0.05176 miRanda -0.13 0.02025 NA
54 hsa-miR-16-2-3p CAPN2 0.5 0.02636 -0.31 0.05176 mirMAP -0.11 0.00157 NA
55 hsa-miR-20a-3p CAPN2 2.52 0 -0.31 0.05176 MirTarget -0.13 0 NA
56 hsa-miR-320b CAPN2 0.23 0.37882 -0.31 0.05176 miRanda -0.12 1.0E-5 NA
57 hsa-miR-421 CAPN2 0.17 0.53528 -0.31 0.05176 miRanda -0.16 0 NA
58 hsa-miR-590-5p CAPN2 2.07 0 -0.31 0.05176 miRanda -0.16 0 NA
59 hsa-miR-148b-5p CASP10 1.39 0 -0.27 0.09806 mirMAP -0.14 2.0E-5 NA
60 hsa-miR-19a-3p CASP10 2.12 0 -0.27 0.09806 MirTarget; mirMAP -0.1 6.0E-5 NA
61 hsa-miR-19b-1-5p CASP10 1.71 0 -0.27 0.09806 mirMAP -0.18 0 NA
62 hsa-miR-19b-3p CASP10 2.11 0 -0.27 0.09806 MirTarget; mirMAP -0.12 0.00012 NA
63 hsa-miR-421 CASP10 0.17 0.53528 -0.27 0.09806 mirMAP -0.17 0 NA
64 hsa-miR-744-3p CASP10 2.07 0 -0.27 0.09806 mirMAP -0.13 0 NA
65 hsa-miR-139-5p CASP3 -2.27 0 0.75 0 miRanda -0.1 0 NA
66 hsa-miR-195-3p CASP3 -1.33 0 0.75 0 MirTarget -0.12 0 NA
67 hsa-miR-30c-5p CASP3 -0.33 0.1236 0.75 0 miRNATAP -0.15 0 NA
68 hsa-miR-30d-5p CASP3 -0.92 4.0E-5 0.75 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.17 0 NA
69 hsa-miR-125a-5p CASP6 -1.05 0 0.9 0 miRanda -0.12 0.00016 NA
70 hsa-miR-664a-3p CASP7 0.44 0.02142 -0.21 0.08139 MirTarget -0.11 0.00018 NA
71 hsa-miR-107 CFLAR 0.66 0 -0.6 0.00015 miRanda -0.15 0.00732 NA
72 hsa-miR-130b-3p CFLAR 1.83 0 -0.6 0.00015 mirMAP -0.17 0 NA
73 hsa-miR-186-5p CFLAR 0.85 0 -0.6 0.00015 mirMAP -0.11 0.03888 NA
74 hsa-miR-320b CFLAR 0.23 0.37882 -0.6 0.00015 miRanda -0.15 0 NA
75 hsa-miR-330-5p CFLAR 0.17 0.33643 -0.6 0.00015 miRanda -0.11 0.0124 NA
76 hsa-miR-421 CFLAR 0.17 0.53528 -0.6 0.00015 miRanda -0.11 0.00019 NA
77 hsa-miR-454-3p CFLAR 1.49 0 -0.6 0.00015 mirMAP -0.11 0.0011 NA
78 hsa-miR-708-5p CFLAR 3.04 0 -0.6 0.00015 mirMAP -0.1 2.0E-5 NA
79 hsa-miR-106b-5p CHP2 1.47 0 -0.7 0.27547 MirTarget -0.29 0.04606 NA
80 hsa-miR-582-5p CHP2 1.08 0.00149 -0.7 0.27547 miRNATAP -0.17 0.04861 NA
81 hsa-miR-15a-5p CHUK 1.63 0 0.04 0.74424 miRNAWalker2 validate; miRTarBase; MirTarget -0.16 0 NA
82 hsa-miR-29b-2-5p CHUK 0.35 0.19484 0.04 0.74424 MirTarget -0.12 0 NA
83 hsa-miR-339-5p CHUK 0.54 0.04881 0.04 0.74424 miRanda -0.1 0 NA
84 hsa-miR-342-3p CHUK -0.13 0.56103 0.04 0.74424 miRanda -0.18 0 NA
85 hsa-miR-497-5p CHUK -0.05 0.78621 0.04 0.74424 MirTarget -0.19 0 NA
86 hsa-miR-15b-3p CSF2RB 0.8 0.0004 -1.28 0 mirMAP -0.15 0.00822 NA
87 hsa-miR-181d-5p CSF2RB 1.19 0 -1.28 0 MirTarget -0.23 8.0E-5 NA
88 hsa-miR-19a-3p CSF2RB 2.12 0 -1.28 0 MirTarget -0.17 4.0E-5 NA
89 hsa-miR-19b-3p CSF2RB 2.11 0 -1.28 0 MirTarget -0.25 0 NA
90 hsa-miR-139-5p CYCS -2.27 0 0.53 0.0008 miRanda -0.18 0 NA
91 hsa-miR-342-3p CYCS -0.13 0.56103 0.53 0.0008 mirMAP -0.1 0.00171 NA
92 hsa-miR-342-3p DFFA -0.13 0.56103 0.21 0.04672 mirMAP -0.12 0 NA
93 hsa-miR-664a-3p DFFA 0.44 0.02142 0.21 0.04672 mirMAP -0.11 1.0E-5 NA
94 hsa-miR-365a-3p DFFB 0.01 0.9536 0.55 2.0E-5 MirTarget -0.12 0 NA
95 hsa-miR-130a-3p ENDOD1 0.88 0.00016 0.06 0.80229 MirTarget -0.16 0.00041 NA
96 hsa-miR-130b-3p ENDOD1 1.83 0 0.06 0.80229 MirTarget -0.21 0 NA
97 hsa-miR-16-1-3p ENDOD1 1.5 0 0.06 0.80229 mirMAP -0.12 0.02926 NA
98 hsa-miR-181d-5p ENDOD1 1.19 0 0.06 0.80229 MirTarget -0.12 0.01524 NA
99 hsa-miR-193a-3p ENDOD1 0.55 0.0319 0.06 0.80229 miRanda -0.18 6.0E-5 NA
100 hsa-miR-193b-3p ENDOD1 1.1 0.00082 0.06 0.80229 miRNAWalker2 validate -0.19 0 NA
101 hsa-miR-19a-3p ENDOD1 2.12 0 0.06 0.80229 mirMAP -0.24 0 NA
102 hsa-miR-19b-3p ENDOD1 2.11 0 0.06 0.80229 mirMAP -0.21 0 NA
103 hsa-miR-20a-3p ENDOD1 2.52 0 0.06 0.80229 MirTarget -0.26 0 NA
104 hsa-miR-26b-3p ENDOD1 1.37 0 0.06 0.80229 mirMAP -0.16 0.00018 NA
105 hsa-miR-301a-3p ENDOD1 2.7 0 0.06 0.80229 MirTarget -0.12 0.00101 NA
106 hsa-miR-330-5p ENDOD1 0.17 0.33643 0.06 0.80229 miRanda -0.18 0.00348 NA
107 hsa-miR-335-3p ENDOD1 1.51 0 0.06 0.80229 MirTarget -0.12 0.01335 NA
108 hsa-miR-454-3p ENDOD1 1.49 0 0.06 0.80229 MirTarget -0.2 4.0E-5 NA
109 hsa-miR-590-3p ENDOD1 0.84 0.00129 0.06 0.80229 miRanda -0.14 0.00426 NA
110 hsa-miR-24-3p EXOG -0.04 0.78587 -0.19 0.08402 MirTarget -0.1 0.00598 NA
111 hsa-miR-106a-5p FAS 1.39 6.0E-5 -0.88 0.00034 miRNAWalker2 validate; miRTarBase -0.27 0 22431000; 27142596 miR 106a is frequently upregulated in gastric cancer and inhibits the extrinsic apoptotic pathway by targeting FAS; Bioinformatic analysis combining with validation experiments identified FAS as a direct target of miR-106a; Moreover a significant inverse correlation was found between miR-106a and FAS expression not only in gastric cancer cell lines but also in gastric cancer specimens; Taken together these findings suggest that ectopicly overexpressed miR-106a may play an oncogenic role in gastric carcinogenesis and impair extrinsic apoptotic pathway through targeting FAS;Functional experiment ascertained that miR-106a interacted with FAS and mediated caspase3 pathway
112 hsa-miR-590-5p FAS 2.07 0 -0.88 0.00034 miRanda -0.28 0 NA
113 hsa-let-7e-5p FASLG -0.75 7.0E-5 0.23 0.52524 miRNATAP -0.24 0.0052 NA
114 hsa-miR-107 IKBKG 0.66 0 0.08 0.54471 miRanda -0.13 0.00969 NA
115 hsa-miR-143-3p IKBKG -1.21 1.0E-5 0.08 0.54471 mirMAP -0.16 0 NA
116 hsa-miR-17-3p IKBKG 1.37 0 0.08 0.54471 mirMAP -0.12 0.00016 NA
117 hsa-miR-24-3p IKBKG -0.04 0.78587 0.08 0.54471 mirMAP -0.14 0.00373 NA
118 hsa-miR-330-3p IKBKG -0.72 0.0008 0.08 0.54471 mirMAP -0.17 0 NA
119 hsa-miR-141-3p IL1A 3.37 0 -2.79 0 MirTarget -0.43 0 NA
120 hsa-miR-181c-5p IL1A 0.53 0.01259 -2.79 0 MirTarget -0.42 4.0E-5 NA
121 hsa-miR-181d-5p IL1A 1.19 0 -2.79 0 MirTarget -0.5 0 NA
122 hsa-miR-200a-3p IL1A 3.15 0 -2.79 0 MirTarget -0.45 0 NA
123 hsa-miR-30b-5p IL1A 0.36 0.13803 -2.79 0 MirTarget -0.37 3.0E-5 NA
124 hsa-miR-30d-5p IL1A -0.92 4.0E-5 -2.79 0 MirTarget -0.36 0.00024 NA
125 hsa-miR-30e-5p IL1A 1.6 0 -2.79 0 MirTarget -0.39 0.00095 NA
126 hsa-miR-335-5p IL1A -0.47 0.0677 -2.79 0 miRNAWalker2 validate -0.36 0.00013 NA
127 hsa-miR-664a-3p IL1A 0.44 0.02142 -2.79 0 MirTarget -0.4 0.00041 NA
128 hsa-miR-21-5p IL1B 4.38 0 -1.42 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget -0.13 0.02018 NA
129 hsa-miR-30d-3p IL1B 0 0.98646 -1.42 1.0E-5 MirTarget -0.19 0.01127 NA
130 hsa-miR-7-1-3p IL1B 2.61 0 -1.42 1.0E-5 MirTarget -0.2 0.00249 NA
131 hsa-miR-130b-5p IL1R1 1.54 0 -0.9 1.0E-5 mirMAP -0.21 0 NA
132 hsa-miR-17-3p IL1R1 1.37 0 -0.9 1.0E-5 mirMAP -0.29 0 NA
133 hsa-miR-186-5p IL1R1 0.85 0 -0.9 1.0E-5 mirMAP -0.33 0 NA
134 hsa-miR-26b-5p IL1R1 0.72 5.0E-5 -0.9 1.0E-5 mirMAP -0.15 0.00501 NA
135 hsa-miR-335-3p IL1R1 1.51 0 -0.9 1.0E-5 mirMAP -0.29 0 NA
136 hsa-miR-361-5p IL1R1 0.21 0.0801 -0.9 1.0E-5 miRanda -0.2 0.01104 NA
137 hsa-miR-590-3p IL1R1 0.84 0.00129 -0.9 1.0E-5 miRanda; miRNATAP -0.17 0.00014 NA
138 hsa-miR-139-5p IL1RAP -2.27 0 0 0.99919 miRanda -0.12 0.00188 NA
139 hsa-miR-16-1-3p IL1RAP 1.5 0 0 0.99919 mirMAP -0.14 0.01202 NA
140 hsa-miR-17-5p IL1RAP 2.07 0 0 0.99919 MirTarget; TargetScan -0.2 1.0E-5 NA
141 hsa-miR-186-5p IL1RAP 0.85 0 0 0.99919 mirMAP -0.22 0.0056 NA
142 hsa-miR-19a-3p IL1RAP 2.12 0 0 0.99919 MirTarget -0.2 0 NA
143 hsa-miR-19b-3p IL1RAP 2.11 0 0 0.99919 MirTarget -0.23 0 NA
144 hsa-miR-204-5p IL1RAP -1.02 0.00767 0 0.99919 miRNAWalker2 validate -0.11 0.00018 NA
145 hsa-miR-20a-5p IL1RAP 2.65 0 0 0.99919 MirTarget -0.21 0 NA
146 hsa-miR-29a-3p IL1RAP 0.1 0.5732 0 0.99919 MirTarget; miRNATAP -0.19 0.00191 NA
147 hsa-miR-29b-3p IL1RAP 3.11 0 0 0.99919 MirTarget; miRNATAP -0.2 0 NA
148 hsa-miR-29c-3p IL1RAP 1.32 0 0 0.99919 MirTarget; miRNATAP -0.17 9.0E-5 NA
149 hsa-miR-375 IL1RAP 0.62 0.1492 0 0.99919 miRNAWalker2 validate; miRanda -0.14 0 NA
150 hsa-miR-454-3p IL1RAP 1.49 0 0 0.99919 MirTarget -0.13 0.0096 NA
NumGOOverlapSizeP ValueAdj. P Value
1 POSITIVE REGULATION OF RESPONSE TO STIMULUS 39 1929 6.935e-26 3.227e-22
2 CELL DEATH 31 1001 4.411e-25 8.838e-22
3 REGULATION OF CELL DEATH 35 1472 5.698e-25 8.838e-22
4 INTRACELLULAR SIGNAL TRANSDUCTION 35 1572 5.146e-24 4.789e-21
5 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 37 1848 4.528e-24 4.789e-21
6 EXTRINSIC APOPTOTIC SIGNALING PATHWAY 15 99 2.897e-22 1.925e-19
7 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 33 1492 2.657e-22 1.925e-19
8 POSITIVE REGULATION OF MOLECULAR FUNCTION 35 1791 3.924e-22 2.046e-19
9 RESPONSE TO OXYGEN CONTAINING COMPOUND 32 1381 3.957e-22 2.046e-19
10 POSITIVE REGULATION OF CELL COMMUNICATION 33 1532 6.081e-22 2.829e-19
11 NEGATIVE REGULATION OF CELL DEATH 26 872 2.96e-20 1.252e-17
12 EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 11 39 8.619e-20 3.085e-17
13 RESPONSE TO CYTOKINE 24 714 8.373e-20 3.085e-17
14 POSITIVE REGULATION OF CATALYTIC ACTIVITY 31 1518 9.919e-20 3.296e-17
15 IMMUNE SYSTEM PROCESS 34 1984 1.478e-19 4.584e-17
16 APOPTOTIC SIGNALING PATHWAY 18 289 1.687e-19 4.907e-17
17 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 25 876 5.715e-19 1.564e-16
18 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 16 213 1.136e-18 2.937e-16
19 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 27 1135 1.414e-18 3.463e-16
20 POSITIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 15 179 2.958e-18 6.554e-16
21 ACTIVATION OF PROTEIN KINASE ACTIVITY 17 279 2.889e-18 6.554e-16
22 RESPONSE TO NITROGEN COMPOUND 24 859 5.876e-18 1.243e-15
23 REGULATION OF KINASE ACTIVITY 23 776 9.764e-18 1.975e-15
24 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 30 1656 1.494e-17 2.897e-15
25 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 19 470 4.599e-17 8.56e-15
26 ACTIVATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 12 95 5.993e-17 1.073e-14
27 POSITIVE REGULATION OF KINASE ACTIVITY 19 482 7.322e-17 1.262e-14
28 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 15 233 1.591e-16 2.644e-14
29 CELLULAR RESPONSE TO CYTOKINE STIMULUS 20 606 2.897e-16 4.649e-14
30 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 24 1036 4.084e-16 5.938e-14
31 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 24 1036 4.084e-16 5.938e-14
32 REGULATION OF PROTEIN MODIFICATION PROCESS 29 1710 3.973e-16 5.938e-14
33 CYTOKINE MEDIATED SIGNALING PATHWAY 18 452 4.672e-16 6.393e-14
34 ZYMOGEN ACTIVATION 12 112 4.667e-16 6.393e-14
35 REGULATION OF TRANSFERASE ACTIVITY 23 946 7.271e-16 9.667e-14
36 REGULATION OF PHOSPHORUS METABOLIC PROCESS 28 1618 9.902e-16 1.28e-13
37 REGULATION OF IMMUNE RESPONSE 22 858 1.252e-15 1.575e-13
38 REGULATION OF IMMUNE SYSTEM PROCESS 26 1403 3.286e-15 4.024e-13
39 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 19 616 6.453e-15 7.698e-13
40 REGULATION OF PEPTIDASE ACTIVITY 16 392 1.781e-14 2.036e-12
41 PHOSPHORYLATION 24 1228 1.794e-14 2.036e-12
42 POSITIVE REGULATION OF IMMUNE RESPONSE 18 563 2.09e-14 2.315e-12
43 POSITIVE REGULATION OF PEPTIDASE ACTIVITY 12 154 2.307e-14 2.497e-12
44 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 20 799 5.449e-14 5.696e-12
45 CELLULAR RESPONSE TO NITROGEN COMPOUND 17 505 5.509e-14 5.696e-12
46 POSITIVE REGULATION OF CELL DEATH 18 605 7.153e-14 7.236e-12
47 PROTEIN PHOSPHORYLATION 21 944 1.076e-13 1.065e-11
48 RESPONSE TO TUMOR NECROSIS FACTOR 13 233 1.312e-13 1.272e-11
49 POSITIVE REGULATION OF NF KAPPAB TRANSCRIPTION FACTOR ACTIVITY 11 132 1.449e-13 1.376e-11
50 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 28 1977 1.572e-13 1.463e-11
51 INFLAMMATORY RESPONSE 16 454 1.714e-13 1.564e-11
52 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 10 98 2.568e-13 2.298e-11
53 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 14 321 3.94e-13 3.459e-11
54 I KAPPAB KINASE NF KAPPAB SIGNALING 9 70 5.057e-13 4.357e-11
55 PROTEIN MATURATION 13 265 6.801e-13 5.651e-11
56 RESPONSE TO ENDOGENOUS STIMULUS 24 1450 6.737e-13 5.651e-11
57 REGULATION OF PROTEOLYSIS 18 711 1.1e-12 8.976e-11
58 ACTIVATION OF IMMUNE RESPONSE 15 427 1.157e-12 9.285e-11
59 TUMOR NECROSIS FACTOR MEDIATED SIGNALING PATHWAY 10 118 1.708e-12 1.347e-10
60 NIK NF KAPPAB SIGNALING 9 83 2.482e-12 1.92e-10
61 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 12 228 2.517e-12 1.92e-10
62 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 19 867 2.828e-12 2.122e-10
63 RESPONSE TO ABIOTIC STIMULUS 20 1024 5.313e-12 3.924e-10
64 REGULATION OF MAP KINASE ACTIVITY 13 319 7.101e-12 5.162e-10
65 RESPONSE TO EXTERNAL STIMULUS 25 1821 1.162e-11 8.315e-10
66 IMMUNE RESPONSE 20 1100 1.943e-11 1.37e-09
67 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 10 153 2.325e-11 1.615e-09
68 RESPONSE TO BACTERIUM 15 528 2.372e-11 1.623e-09
69 POSITIVE REGULATION OF PROTEOLYSIS 13 363 3.57e-11 2.373e-09
70 REGULATION OF APOPTOTIC SIGNALING PATHWAY 13 363 3.57e-11 2.373e-09
71 POSITIVE REGULATION OF DEFENSE RESPONSE 13 364 3.694e-11 2.421e-09
72 RESPONSE TO BIOTIC STIMULUS 18 886 4.239e-11 2.74e-09
73 RESPONSE TO WOUNDING 15 563 5.844e-11 3.725e-09
74 POSITIVE REGULATION OF MAPK CASCADE 14 470 6.541e-11 4.113e-09
75 TOLL LIKE RECEPTOR SIGNALING PATHWAY 8 85 1.413e-10 8.766e-09
76 IMMUNE RESPONSE REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 12 323 1.458e-10 8.926e-09
77 ACTIVATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC SIGNALING PATHWAY 5 13 2.374e-10 1.435e-08
78 EXECUTION PHASE OF APOPTOSIS 7 55 2.446e-10 1.459e-08
79 FC EPSILON RECEPTOR SIGNALING PATHWAY 9 142 3.3e-10 1.92e-08
80 NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 10 200 3.276e-10 1.92e-08
81 REGULATION OF RESPONSE TO CYTOKINE STIMULUS 9 144 3.74e-10 2.148e-08
82 ACTIVATION OF INNATE IMMUNE RESPONSE 10 204 3.975e-10 2.256e-08
83 REGULATION OF MAPK CASCADE 15 660 5.312e-10 2.978e-08
84 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 12 365 5.904e-10 3.271e-08
85 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 6 34 6.401e-10 3.504e-08
86 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 11 289 7.176e-10 3.882e-08
87 WOUND HEALING 13 470 8.55e-10 4.573e-08
88 PATTERN RECOGNITION RECEPTOR SIGNALING PATHWAY 8 109 1.056e-09 5.585e-08
89 POSITIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC SIGNALING PATHWAY 5 17 1.131e-09 5.915e-08
90 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 9 171 1.721e-09 8.899e-08
91 POSITIVE REGULATION OF INNATE IMMUNE RESPONSE 10 246 2.445e-09 1.25e-07
92 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 17 1008 2.856e-09 1.429e-07
93 CELLULAR COMPONENT DISASSEMBLY INVOLVED IN EXECUTION PHASE OF APOPTOSIS 6 43 2.843e-09 1.429e-07
94 INOSITOL LIPID MEDIATED SIGNALING 8 124 2.958e-09 1.464e-07
95 REGULATION OF RESPONSE TO STRESS 20 1468 3.161e-09 1.548e-07
96 REGULATION OF DEFENSE RESPONSE 15 759 3.578e-09 1.727e-07
97 RESPONSE TO LIPID 16 888 3.637e-09 1.727e-07
98 CELLULAR RESPONSE TO MECHANICAL STIMULUS 7 80 3.617e-09 1.727e-07
99 REGULATION OF HYDROLASE ACTIVITY 19 1327 3.938e-09 1.851e-07
100 HOMEOSTATIC PROCESS 19 1337 4.456e-09 2.073e-07
101 POSITIVE REGULATION OF HYDROLASE ACTIVITY 16 905 4.765e-09 2.174e-07
102 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC SIGNALING PATHWAY 5 22 4.761e-09 2.174e-07
103 PROTEOLYSIS 18 1208 6.12e-09 2.764e-07
104 PHOSPHATIDYLINOSITOL 3 PHOSPHATE BIOSYNTHETIC PROCESS 6 49 6.433e-09 2.878e-07
105 REGULATION OF INNATE IMMUNE RESPONSE 11 357 6.542e-09 2.899e-07
106 REGULATION OF TUMOR NECROSIS FACTOR MEDIATED SIGNALING PATHWAY 6 50 7.293e-09 3.201e-07
107 POSITIVE REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 6 51 8.247e-09 3.553e-07
108 DEFENSE RESPONSE 18 1231 8.218e-09 3.553e-07
109 FC RECEPTOR SIGNALING PATHWAY 9 206 8.817e-09 3.764e-07
110 POSITIVE REGULATION OF GENE EXPRESSION 21 1733 9.035e-09 3.822e-07
111 POSITIVE REGULATION OF MAP KINASE ACTIVITY 9 207 9.197e-09 3.855e-07
112 PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 5 25 9.54e-09 3.963e-07
113 RESPONSE TO INORGANIC SUBSTANCE 12 479 1.252e-08 5.156e-07
114 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 6 55 1.315e-08 5.369e-07
115 INTRINSIC APOPTOTIC SIGNALING PATHWAY 8 152 1.477e-08 5.978e-07
116 NECROTIC CELL DEATH 5 28 1.753e-08 7.031e-07
117 POSITIVE REGULATION OF NIK NF KAPPAB SIGNALING 5 29 2.113e-08 8.404e-07
118 POSITIVE REGULATION OF NFAT PROTEIN IMPORT INTO NUCLEUS 4 11 2.219e-08 8.75e-07
119 POSITIVE REGULATION OF PROTEIN IMPORT 7 104 2.29e-08 8.954e-07
120 RESPONSE TO PEPTIDE 11 404 2.339e-08 9.07e-07
121 CHEMICAL HOMEOSTASIS 15 874 2.367e-08 9.103e-07
122 RESPONSE TO HORMONE 15 893 3.146e-08 1.2e-06
123 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 5 32 3.559e-08 1.346e-06
124 SIGNAL TRANSDUCTION IN ABSENCE OF LIGAND 5 33 4.185e-08 1.558e-06
125 EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 5 33 4.185e-08 1.558e-06
126 RESPONSE TO INTERLEUKIN 1 7 115 4.606e-08 1.701e-06
127 INTERLEUKIN 1 MEDIATED SIGNALING PATHWAY 4 13 4.787e-08 1.754e-06
128 REGULATION OF NEURON DEATH 9 252 5.036e-08 1.831e-06
129 NEGATIVE REGULATION OF MOLECULAR FUNCTION 16 1079 5.626e-08 2.029e-06
130 NEURON APOPTOTIC PROCESS 5 35 5.699e-08 2.04e-06
131 PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROCESS 7 120 6.183e-08 2.196e-06
132 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 7 121 6.548e-08 2.308e-06
133 RESPONSE TO OXIDATIVE STRESS 10 352 7.335e-08 2.566e-06
134 CELLULAR RESPONSE TO EXTERNAL STIMULUS 9 264 7.499e-08 2.604e-06
135 CELLULAR RESPONSE TO CARBOHYDRATE STIMULUS 6 74 8.051e-08 2.775e-06
136 CELLULAR GLUCOSE HOMEOSTASIS 6 75 8.731e-08 2.967e-06
137 RESPONSE TO REACTIVE OXYGEN SPECIES 8 191 8.736e-08 2.967e-06
138 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 10 360 9.045e-08 3.05e-06
139 ANTIGEN RECEPTOR MEDIATED SIGNALING PATHWAY 8 195 1.025e-07 3.398e-06
140 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 7 129 1.018e-07 3.398e-06
141 CELLULAR RESPONSE TO PEPTIDE 9 274 1.03e-07 3.398e-06
142 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 10 370 1.167e-07 3.824e-06
143 REGULATION OF NIK NF KAPPAB SIGNALING 5 42 1.47e-07 4.783e-06
144 REGULATION OF NFAT PROTEIN IMPORT INTO NUCLEUS 4 17 1.579e-07 5.034e-06
145 ACTIVATION OF NF KAPPAB INDUCING KINASE ACTIVITY 4 17 1.579e-07 5.034e-06
146 ACTIVATION OF PROTEIN KINASE A ACTIVITY 4 17 1.579e-07 5.034e-06
147 REGULATION OF CELL PROLIFERATION 18 1496 1.627e-07 5.151e-06
148 RESPONSE TO MECHANICAL STIMULUS 8 210 1.811e-07 5.693e-06
149 REGULATION OF INFLAMMATORY RESPONSE 9 294 1.872e-07 5.846e-06
150 CELLULAR RESPONSE TO INTERLEUKIN 1 6 88 2.281e-07 7.077e-06
151 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 5 46 2.348e-07 7.234e-06
152 T CELL RECEPTOR SIGNALING PATHWAY 7 146 2.375e-07 7.27e-06
153 REGULATION OF CELL ADHESION 12 629 2.443e-07 7.429e-06
154 NEURON DEATH 5 47 2.621e-07 7.92e-06
155 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 11 514 2.665e-07 7.999e-06
156 RESPONSE TO OXYGEN LEVELS 9 311 3.008e-07 8.915e-06
157 HEMOSTASIS 9 311 3.008e-07 8.915e-06
158 RESPONSE TO ORGANIC CYCLIC COMPOUND 14 917 3.179e-07 9.363e-06
159 REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 6 95 3.601e-07 1.054e-05
160 NECROPTOTIC PROCESS 4 21 3.937e-07 1.145e-05
161 RESPONSE TO NICOTINE 5 51 3.978e-07 1.15e-05
162 LIPID PHOSPHORYLATION 6 99 4.601e-07 1.321e-05
163 CELLULAR RESPONSE TO HORMONE STIMULUS 11 552 5.403e-07 1.542e-05
164 RENAL SYSTEM PROCESS 6 102 5.491e-07 1.558e-05
165 STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 6 103 5.817e-07 1.641e-05
166 RESPONSE TO CARBOHYDRATE 7 168 6.151e-07 1.724e-05
167 REGULATION OF CYTOKINE PRODUCTION 11 563 6.563e-07 1.829e-05
168 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 13 829 6.707e-07 1.858e-05
169 CELL ACTIVATION 11 568 7.159e-07 1.971e-05
170 LEUKOCYTE CELL CELL ADHESION 8 255 7.914e-07 2.166e-05
171 POSITIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 8 258 8.642e-07 2.352e-05
172 RESPONSE TO AMINO ACID 6 112 9.537e-07 2.58e-05
173 DEVELOPMENTAL PROGRAMMED CELL DEATH 4 26 9.727e-07 2.601e-05
174 REGULATION OF NECROTIC CELL DEATH 4 26 9.727e-07 2.601e-05
175 CELLULAR RESPONSE TO ABIOTIC STIMULUS 8 263 9.984e-07 2.655e-05
176 REGULATION OF PROTEIN IMPORT 7 183 1.093e-06 2.89e-05
177 DNA CATABOLIC PROCESS 4 27 1.139e-06 2.995e-05
178 MULTICELLULAR ORGANISMAL HOMEOSTASIS 8 272 1.285e-06 3.359e-05
179 NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR SIGNALING PATHWAY 4 28 1.326e-06 3.448e-05
180 REGULATION OF NEURON APOPTOTIC PROCESS 7 192 1.507e-06 3.895e-05
181 PHOSPHATIDYLINOSITOL METABOLIC PROCESS 7 193 1.56e-06 4.01e-05
182 CELLULAR RESPONSE TO STRESS 17 1565 1.653e-06 4.227e-05
183 REGULATION OF LIPID METABOLIC PROCESS 8 282 1.683e-06 4.278e-05
184 MYD88 INDEPENDENT TOLL LIKE RECEPTOR SIGNALING PATHWAY 4 30 1.767e-06 4.469e-05
185 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 6 126 1.902e-06 4.783e-05
186 LIPOPOLYSACCHARIDE MEDIATED SIGNALING PATHWAY 4 31 2.025e-06 5.065e-05
187 LEUKOCYTE DIFFERENTIATION 8 292 2.181e-06 5.427e-05
188 MYD88 DEPENDENT TOLL LIKE RECEPTOR SIGNALING PATHWAY 4 32 2.309e-06 5.654e-05
189 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 4 32 2.309e-06 5.654e-05
190 NEGATIVE REGULATION OF SIGNAL TRANSDUCTION IN ABSENCE OF LIGAND 4 32 2.309e-06 5.654e-05
191 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 18 1805 2.554e-06 6.223e-05
192 CYTOPLASMIC PATTERN RECOGNITION RECEPTOR SIGNALING PATHWAY 4 33 2.622e-06 6.353e-05
193 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 9 404 2.636e-06 6.355e-05
194 GLYCEROLIPID BIOSYNTHETIC PROCESS 7 211 2.822e-06 6.767e-05
195 T CELL HOMEOSTASIS 4 34 2.965e-06 7.002e-05
196 PROTEIN KINASE B SIGNALING 4 34 2.965e-06 7.002e-05
197 RENAL WATER HOMEOSTASIS 4 34 2.965e-06 7.002e-05
198 RESPONSE TO ALKALOID 6 137 3.095e-06 7.237e-05
199 ACTIVATION OF MAPK ACTIVITY 6 137 3.095e-06 7.237e-05
200 REGULATION OF RESPONSE TO WOUNDING 9 413 3.155e-06 7.319e-05
201 REGULATION OF PROTEIN TARGETING 8 307 3.162e-06 7.319e-05
202 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 7 218 3.501e-06 8.064e-05
203 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 7 220 3.718e-06 8.523e-05
204 CELLULAR HOMEOSTASIS 11 676 3.873e-06 8.833e-05
205 REGULATION OF NECROPTOTIC PROCESS 3 11 3.957e-06 8.98e-05
206 RESPONSE TO ACID CHEMICAL 8 319 4.196e-06 9.477e-05
207 REGULATION OF CELLULAR PROTEIN LOCALIZATION 10 552 4.404e-06 9.898e-05
208 RESPONSE TO DRUG 9 431 4.463e-06 9.983e-05
209 CELLULAR RESPONSE TO GLUCAGON STIMULUS 4 38 4.677e-06 0.0001041
210 REGULATION OF VITAMIN METABOLIC PROCESS 3 12 5.264e-06 0.0001161
211 POSITIVE REGULATION OF GLUCOSE IMPORT IN RESPONSE TO INSULIN STIMULUS 3 12 5.264e-06 0.0001161
212 PHOSPHOLIPID BIOSYNTHETIC PROCESS 7 235 5.737e-06 0.0001259
213 CELLULAR CHEMICAL HOMEOSTASIS 10 570 5.843e-06 0.0001276
214 NEGATIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 5 88 6.104e-06 0.0001327
215 IMMUNE SYSTEM DEVELOPMENT 10 582 7.015e-06 0.0001511
216 LYMPHOCYTE ACTIVATION 8 342 6.99e-06 0.0001511
217 SINGLE ORGANISM CELL ADHESION 9 459 7.417e-06 0.000159
218 REGULATION OF CATABOLIC PROCESS 11 731 8.141e-06 0.0001738
219 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 9 465 8.232e-06 0.0001749
220 CELLULAR RESPONSE TO BIOTIC STIMULUS 6 163 8.425e-06 0.0001782
221 TOLL LIKE RECEPTOR 9 SIGNALING PATHWAY 3 14 8.673e-06 0.0001818
222 REGULATION OF CAMP DEPENDENT PROTEIN KINASE ACTIVITY 3 14 8.673e-06 0.0001818
223 GLUCOSE HOMEOSTASIS 6 170 1.071e-05 0.0002208
224 LEUKOCYTE MIGRATION 7 259 1.082e-05 0.0002208
225 CARBOHYDRATE HOMEOSTASIS 6 170 1.071e-05 0.0002208
226 APOPTOTIC DNA FRAGMENTATION 3 15 1.082e-05 0.0002208
227 NEUROTROPHIN TRK RECEPTOR SIGNALING PATHWAY 3 15 1.082e-05 0.0002208
228 T CELL APOPTOTIC PROCESS 3 15 1.082e-05 0.0002208
229 NEGATIVE REGULATION OF NEURON DEATH 6 171 1.108e-05 0.0002251
230 REGULATION OF CELL ACTIVATION 9 484 1.134e-05 0.0002294
231 REGULATION OF GLUCOSE TRANSPORT 5 100 1.142e-05 0.00023
232 RESPONSE TO GLUCAGON 4 48 1.206e-05 0.0002419
233 POSITIVE REGULATION OF CYTOKINE PRODUCTION 8 370 1.238e-05 0.0002463
234 REGULATION OF INTRACELLULAR TRANSPORT 10 621 1.234e-05 0.0002463
235 RESPONSE TO CORTICOSTEROID 6 176 1.305e-05 0.0002585
236 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 13 1087 1.314e-05 0.000259
237 LYMPHOCYTE HOMEOSTASIS 4 50 1.421e-05 0.000279
238 REGULATION OF CELL CELL ADHESION 8 380 1.501e-05 0.0002931
239 POSITIVE REGULATION OF TRANSPORT 12 936 1.505e-05 0.0002931
240 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 8 381 1.53e-05 0.0002967
241 REGULATION OF BODY FLUID LEVELS 9 506 1.614e-05 0.0003104
242 REGULATION OF GLUCOSE IMPORT IN RESPONSE TO INSULIN STIMULUS 3 17 1.61e-05 0.0003104
243 REGULATION OF LIPID CATABOLIC PROCESS 4 52 1.663e-05 0.0003185
244 REGULATION OF PROTEIN LOCALIZATION 12 950 1.745e-05 0.0003328
245 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 7 282 1.875e-05 0.0003561
246 INOSITOL PHOSPHATE MEDIATED SIGNALING 3 18 1.928e-05 0.0003632
247 LYMPHOCYTE APOPTOTIC PROCESS 3 18 1.928e-05 0.0003632
248 PROTEIN DEPHOSPHORYLATION 6 190 2.014e-05 0.0003779
249 DNA CATABOLIC PROCESS ENDONUCLEOLYTIC 3 19 2.285e-05 0.000427
250 MULTICELLULAR ORGANISMAL WATER HOMEOSTASIS 4 58 2.573e-05 0.0004788
251 GLYCEROPHOSPHOLIPID METABOLIC PROCESS 7 297 2.614e-05 0.0004846
252 REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 4 59 2.754e-05 0.0005085
253 LEUKOCYTE ACTIVATION 8 414 2.775e-05 0.0005103
254 REGULATION OF GLUCOSE IMPORT 4 60 2.944e-05 0.0005351
255 NEGATIVE REGULATION OF CATABOLIC PROCESS 6 203 2.924e-05 0.0005351
256 LEUKOCYTE HOMEOSTASIS 4 60 2.944e-05 0.0005351
257 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 12 1004 3.013e-05 0.0005456
258 REGULATION OF ORGANELLE ORGANIZATION 13 1178 3.069e-05 0.0005536
259 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 14 1360 3.1e-05 0.0005567
260 NEGATIVE REGULATION OF LIPID CATABOLIC PROCESS 3 21 3.123e-05 0.0005567
261 RESPONSE TO NITRIC OXIDE 3 21 3.123e-05 0.0005567
262 REGULATION OF HOMOTYPIC CELL CELL ADHESION 7 307 3.229e-05 0.0005735
263 LYMPHOCYTE DIFFERENTIATION 6 209 3.443e-05 0.0006091
264 NEGATIVE REGULATION OF CELL COMMUNICATION 13 1192 3.472e-05 0.0006119
265 LIPID MODIFICATION 6 210 3.536e-05 0.0006209
266 POSITIVE REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 3 23 4.141e-05 0.000719
267 LEUKOCYTE APOPTOTIC PROCESS 3 23 4.141e-05 0.000719
268 NEUROTROPHIN SIGNALING PATHWAY 3 23 4.141e-05 0.000719
269 REGULATION OF TRANSPORT 16 1804 4.634e-05 0.0008015
270 REGULATION OF EXECUTION PHASE OF APOPTOSIS 3 24 4.723e-05 0.0008139
271 CELLULAR EXTRAVASATION 3 25 5.355e-05 0.0009161
272 APOPTOTIC NUCLEAR CHANGES 3 25 5.355e-05 0.0009161
273 RESPONSE TO METAL ION 7 333 5.406e-05 0.0009196
274 WATER HOMEOSTASIS 4 70 5.415e-05 0.0009196
275 PLATELET ACTIVATION 5 142 6.184e-05 0.001046
276 RESPONSE TO ENDOPLASMIC RETICULUM STRESS 6 233 6.306e-05 0.001063
277 CELL CELL ADHESION 9 608 6.763e-05 0.001136
278 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 11 926 7.183e-05 0.001202
279 RESPONSE TO GROWTH FACTOR 8 475 7.313e-05 0.00122
280 RESPONSE TO TEMPERATURE STIMULUS 5 148 7.526e-05 0.001251
281 POSITIVE REGULATION OF ACUTE INFLAMMATORY RESPONSE 3 28 7.58e-05 0.001254
282 RESPONSE TO TOXIC SUBSTANCE 6 241 7.599e-05 0.001254
283 REGULATION OF CYTOPLASMIC TRANSPORT 8 481 7.981e-05 0.001308
284 POSITIVE REGULATION OF CELL CELL ADHESION 6 243 7.954e-05 0.001308
285 GLYCEROLIPID METABOLIC PROCESS 7 356 8.22e-05 0.001342
286 REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 3 29 8.437e-05 0.001363
287 POSITIVE REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 3 29 8.437e-05 0.001363
288 MUSCLE ADAPTATION 3 29 8.437e-05 0.001363
289 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 5 152 8.538e-05 0.001375
290 NEGATIVE REGULATION OF LIPID METABOLIC PROCESS 4 80 9.139e-05 0.001461
291 INSULIN RECEPTOR SIGNALING PATHWAY 4 80 9.139e-05 0.001461
292 NEGATIVE REGULATION OF KINASE ACTIVITY 6 250 9.299e-05 0.001482
293 PHOSPHOLIPID METABOLIC PROCESS 7 364 9.442e-05 0.001499
294 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 11 957 9.638e-05 0.001525
295 JNK CASCADE 4 82 0.0001006 0.001582
296 REGULATION OF PROTEIN MATURATION 4 82 0.0001006 0.001582
297 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 8 498 0.0001016 0.001591
298 POSITIVE REGULATION OF INTERLEUKIN 2 PRODUCTION 3 31 0.0001034 0.001614
299 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 7 372 0.0001081 0.001682
300 AGING 6 264 0.0001253 0.001944
301 CELLULAR COMPONENT DISASSEMBLY 8 515 0.000128 0.001979
302 POSITIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 4 88 0.0001324 0.00204
303 CELLULAR RESPONSE TO ALKALOID 3 34 0.0001367 0.0021
304 RESPONSE TO HEAT 4 89 0.0001383 0.002117
305 NEGATIVE REGULATION OF PROTEIN COMPLEX DISASSEMBLY 5 170 0.0001445 0.002205
306 NEGATIVE REGULATION OF PROTEIN PROCESSING 3 35 0.0001492 0.002262
307 NEGATIVE REGULATION OF PROTEIN MATURATION 3 35 0.0001492 0.002262
308 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 15 1784 0.0001553 0.002346
309 STRIATED MUSCLE CELL DIFFERENTIATION 5 173 0.0001568 0.002362
310 POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 3 36 0.0001625 0.002438
311 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 9 684 0.0001652 0.002472
312 REGULATION OF CYTOKINE BIOSYNTHETIC PROCESS 4 94 0.0001709 0.002548
313 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 13 1395 0.0001721 0.002558
314 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 9 689 0.0001745 0.002586
315 DEPHOSPHORYLATION 6 286 0.0001936 0.002859
316 WNT SIGNALING PATHWAY CALCIUM MODULATING PATHWAY 3 39 0.0002066 0.003043
317 CELL DEVELOPMENT 13 1426 0.0002139 0.00314
318 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 3 40 0.0002229 0.003262
319 MYELOID CELL DIFFERENTIATION 5 189 0.0002366 0.003452
320 MITOTIC SPINDLE ASSEMBLY 3 41 0.00024 0.003479
321 MICROTUBULE CYTOSKELETON ORGANIZATION INVOLVED IN MITOSIS 3 41 0.00024 0.003479
322 REGULATION OF IMMUNE EFFECTOR PROCESS 7 424 0.0002416 0.003491
323 REGULATION OF INTERLEUKIN 6 PRODUCTION 4 104 0.0002521 0.003631
324 POSITIVE REGULATION OF GLUCOSE TRANSPORT 3 42 0.0002579 0.003704
325 INNATE IMMUNE RESPONSE ACTIVATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 4 106 0.0002711 0.003882
326 REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 3 43 0.0002767 0.00395
327 REGULATION OF CELLULAR LOCALIZATION 12 1277 0.0002965 0.004219
328 RESPONSE TO HYDROGEN PEROXIDE 4 109 0.0003016 0.004279
329 POSITIVE REGULATION OF CELL ACTIVATION 6 311 0.0003037 0.004295
330 REGULATION OF ALCOHOL BIOSYNTHETIC PROCESS 3 45 0.0003168 0.004467
331 ORGANOPHOSPHATE BIOSYNTHETIC PROCESS 7 450 0.0003463 0.004868
332 REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY 4 114 0.0003579 0.005016
333 POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS 3 47 0.0003605 0.005038
334 CELLULAR RESPONSE TO LIPID 7 457 0.00038 0.005294
335 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 3 48 0.0003838 0.005299
336 REGULATION OF LIPID KINASE ACTIVITY 3 48 0.0003838 0.005299
337 REGULATION OF INTERLEUKIN 2 PRODUCTION 3 48 0.0003838 0.005299
338 REGULATION OF TOLL LIKE RECEPTOR SIGNALING PATHWAY 3 49 0.0004079 0.005583
339 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 4 118 0.000408 0.005583
340 REGULATION OF STEROID BIOSYNTHETIC PROCESS 3 49 0.0004079 0.005583
341 INNATE IMMUNE RESPONSE 8 619 0.0004437 0.006055
342 REGULATION OF PROTEIN COMPLEX DISASSEMBLY 5 217 0.0004465 0.006075
343 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 4 122 0.0004629 0.006243
344 REGULATION OF FEVER GENERATION 2 11 0.0004626 0.006243
345 NEGATIVE REGULATION OF NECROTIC CELL DEATH 2 11 0.0004626 0.006243
346 REGULATION OF ADAPTIVE IMMUNE RESPONSE 4 123 0.0004774 0.006402
347 T CELL DIFFERENTIATION 4 123 0.0004774 0.006402
348 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 11 1152 0.000481 0.006432
349 REGULATION OF T CELL MEDIATED IMMUNITY 3 52 0.0004863 0.006465
350 ACTIVATION OF MAPKK ACTIVITY 3 52 0.0004863 0.006465
351 REGULATION OF NITRIC OXIDE BIOSYNTHETIC PROCESS 3 53 0.0005144 0.006799
352 CELLULAR RESPONSE TO AMINO ACID STIMULUS 3 53 0.0005144 0.006799
353 REGULATION OF ENDOTHELIAL CELL DEVELOPMENT 2 12 0.000554 0.007181
354 REGULATION OF CHEMOKINE BIOSYNTHETIC PROCESS 2 12 0.000554 0.007181
355 SYSTEM PROCESS 14 1785 0.0005513 0.007181
356 REGULATION OF ESTABLISHMENT OF ENDOTHELIAL BARRIER 2 12 0.000554 0.007181
357 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 10 983 0.00055 0.007181
358 POSITIVE REGULATION OF INTERLEUKIN 2 BIOSYNTHETIC PROCESS 2 12 0.000554 0.007181
359 IMMUNE EFFECTOR PROCESS 7 486 0.0005486 0.007181
360 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 6 351 0.0005764 0.007449
361 B CELL ACTIVATION 4 132 0.000623 0.00803
362 REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 3 57 0.0006371 0.008189
363 POSITIVE REGULATION OF STEROID BIOSYNTHETIC PROCESS 2 13 0.0006535 0.008308
364 HEPATOCYTE APOPTOTIC PROCESS 2 13 0.0006535 0.008308
365 RESPONSE TO COBALT ION 2 13 0.0006535 0.008308
366 REGULATION OF PROTEIN POLYUBIQUITINATION 2 13 0.0006535 0.008308
367 MUSCLE CELL DIFFERENTIATION 5 237 0.0006661 0.008445
368 POSITIVE REGULATION OF CYTOKINE BIOSYNTHETIC PROCESS 3 58 0.0006705 0.008478
369 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 4 135 0.0006778 0.008501
370 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 4 135 0.0006778 0.008501
371 RESPONSE TO ALCOHOL 6 362 0.0006774 0.008501
372 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 4 138 0.000736 0.009206
373 REGULATION OF MONOOXYGENASE ACTIVITY 3 60 0.0007405 0.009237
374 REGULATION OF FIBROBLAST APOPTOTIC PROCESS 2 14 0.000761 0.009419
375 CELL PROLIFERATION 8 672 0.0007612 0.009419
376 T CELL MIGRATION 2 14 0.000761 0.009419
377 NEGATIVE REGULATION OF PEPTIDASE ACTIVITY 5 245 0.0007735 0.009546
378 REGULATION OF PHOSPHOLIPID METABOLIC PROCESS 3 61 0.0007772 0.009566
379 RESPONSE TO VIRUS 5 247 0.0008022 0.009823
380 BIOLOGICAL ADHESION 10 1032 0.0008017 0.009823
NumGOOverlapSizeP ValueAdj. P Value
1 KINASE ACTIVITY 18 842 1.835e-11 8.871e-09
2 CYTOKINE RECEPTOR BINDING 12 271 1.91e-11 8.871e-09
3 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY BINDING 7 47 7.72e-11 2.391e-08
4 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 18 992 2.665e-10 6.189e-08
5 CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC PROCESS 5 15 5.515e-10 1.025e-07
6 DEATH RECEPTOR BINDING 5 18 1.563e-09 2.074e-07
7 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 7 70 1.396e-09 2.074e-07
8 X1 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 6 43 2.843e-09 3.301e-07
9 PHOSPHATIDYLINOSITOL KINASE ACTIVITY 6 51 8.247e-09 7.661e-07
10 DEATH RECEPTOR ACTIVITY 5 24 7.649e-09 7.661e-07
11 PROTEASE BINDING 7 104 2.29e-08 1.934e-06
12 PROTEIN KINASE ACTIVITY 13 640 3.416e-08 2.645e-06
13 ENZYME BINDING 20 1737 5.457e-08 3.9e-06
14 PROTEIN SERINE THREONINE KINASE ACTIVITY 11 445 6.261e-08 4.154e-06
15 KINASE REGULATOR ACTIVITY 8 186 7.117e-08 4.408e-06
16 PHOSPHATIDYLINOSITOL PHOSPHATE KINASE ACTIVITY 4 16 1.21e-07 7.028e-06
17 CYSTEINE TYPE ENDOPEPTIDASE REGULATOR ACTIVITY INVOLVED IN APOPTOTIC PROCESS 5 42 1.47e-07 8.034e-06
18 CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 6 86 1.988e-07 9.721e-06
19 ADENYL NUCLEOTIDE BINDING 18 1514 1.947e-07 9.721e-06
20 ENZYME REGULATOR ACTIVITY 14 959 5.456e-07 2.534e-05
21 PROTEIN HETERODIMERIZATION ACTIVITY 10 468 1.007e-06 4.338e-05
22 UBIQUITIN LIKE PROTEIN LIGASE BINDING 8 264 1.027e-06 4.338e-05
23 MOLECULAR FUNCTION REGULATOR 16 1353 1.201e-06 4.85e-05
24 PROTEIN SERINE THREONINE KINASE INHIBITOR ACTIVITY 4 30 1.767e-06 6.841e-05
25 RIBONUCLEOTIDE BINDING 18 1860 3.916e-06 0.0001414
26 INSULIN RECEPTOR SUBSTRATE BINDING 3 11 3.957e-06 0.0001414
27 IDENTICAL PROTEIN BINDING 14 1209 8.251e-06 0.0002839
28 NEUROTROPHIN RECEPTOR BINDING 3 14 8.673e-06 0.0002878
29 PROTEIN KINASE A CATALYTIC SUBUNIT BINDING 3 15 1.082e-05 0.0003466
30 INTERLEUKIN 1 RECEPTOR BINDING 3 16 1.329e-05 0.0004115
31 ENZYME INHIBITOR ACTIVITY 8 378 1.445e-05 0.0004332
32 CYSTEINE TYPE PEPTIDASE ACTIVITY 6 184 1.68e-05 0.0004877
33 RECEPTOR BINDING 15 1476 1.757e-05 0.0004946
34 PROTEIN DIMERIZATION ACTIVITY 13 1149 2.364e-05 0.0006459
35 SIGNAL TRANSDUCER ACTIVITY 16 1731 2.796e-05 0.0007421
36 PROTEIN SERINE THREONINE PHOSPHATASE ACTIVITY 4 64 3.803e-05 0.0009813
37 PEPTIDASE REGULATOR ACTIVITY 6 214 3.929e-05 0.0009864
38 CAMP BINDING 3 23 4.141e-05 0.0009864
39 CYSTEINE TYPE ENDOPEPTIDASE INHIBITOR ACTIVITY INVOLVED IN APOPTOTIC PROCESS 3 23 4.141e-05 0.0009864
40 TUMOR NECROSIS FACTOR RECEPTOR BINDING 3 30 9.355e-05 0.002173
41 KINASE INHIBITOR ACTIVITY 4 89 0.0001383 0.003134
42 CYCLIC NUCLEOTIDE BINDING 3 36 0.0001625 0.003593
43 PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 5 178 0.0001791 0.00387
44 PROTEIN KINASE A BINDING 3 42 0.0002579 0.005446
45 KINASE BINDING 8 606 0.0003854 0.007956
46 PROTEIN PHOSPHATASE BINDING 4 120 0.0004348 0.008781
NumGOOverlapSizeP ValueAdj. P Value
1 TRANSFERASE COMPLEX TRANSFERRING PHOSPHORUS CONTAINING GROUPS 13 237 1.632e-13 4.766e-11
2 PHOSPHATIDYLINOSITOL 3 KINASE COMPLEX 7 20 1.012e-13 4.766e-11
3 CATALYTIC COMPLEX 20 1038 6.8e-12 1.324e-09
4 MEMBRANE MICRODOMAIN 12 288 3.875e-11 5.658e-09
5 MEMBRANE PROTEIN COMPLEX 17 1020 3.412e-09 3.986e-07
6 TRANSFERASE COMPLEX 14 703 1.187e-08 1.156e-06
7 PROTEIN KINASE COMPLEX 6 90 2.609e-07 2.177e-05
8 CILIARY BASE 4 23 5.799e-07 4.233e-05
9 CD40 RECEPTOR COMPLEX 3 11 3.957e-06 0.0002567
10 EXTRINSIC COMPONENT OF MEMBRANE 7 252 9.055e-06 0.0005288
11 PHOSPHATASE COMPLEX 4 48 1.206e-05 0.0006404
12 PLASMA MEMBRANE PROTEIN COMPLEX 9 510 1.718e-05 0.0008362
13 MEMBRANE REGION 13 1134 2.058e-05 0.0009246
14 INTRINSIC COMPONENT OF PLASMA MEMBRANE 15 1649 6.39e-05 0.002665
15 VACUOLE 12 1180 0.0001424 0.005543
16 PLASMA MEMBRANE RECEPTOR COMPLEX 5 175 0.0001655 0.00604

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04210_Apoptosis 59 89 1.176e-150 2.117e-148
2 hsa04380_Osteoclast_differentiation 21 128 6.47e-32 5.823e-30
3 hsa04660_T_cell_receptor_signaling_pathway 19 108 1.82e-29 1.052e-27
4 hsa04650_Natural_killer_cell_mediated_cytotoxicity 20 136 2.337e-29 1.052e-27
5 hsa04662_B_cell_receptor_signaling_pathway 17 75 2.005e-28 7.217e-27
6 hsa04010_MAPK_signaling_pathway 23 268 3.027e-28 9.081e-27
7 hsa04722_Neurotrophin_signaling_pathway 17 127 3.248e-24 8.352e-23
8 hsa04620_Toll.like_receptor_signaling_pathway 16 102 5.613e-24 1.263e-22
9 hsa04370_VEGF_signaling_pathway 14 76 4.287e-22 8.575e-21
10 hsa04910_Insulin_signaling_pathway 14 138 2.883e-18 5.19e-17
11 hsa04062_Chemokine_signaling_pathway 14 189 2.554e-16 4.179e-15
12 hsa04510_Focal_adhesion 14 200 5.663e-16 8.495e-15
13 hsa04914_Progesterone.mediated_oocyte_maturation 11 87 1.295e-15 1.794e-14
14 hsa04151_PI3K_AKT_signaling_pathway 16 351 3.189e-15 4.1e-14
15 hsa04014_Ras_signaling_pathway 14 236 5.724e-15 6.576e-14
16 hsa04973_Carbohydrate_digestion_and_absorption 9 44 5.845e-15 6.576e-14
17 hsa04664_Fc_epsilon_RI_signaling_pathway 10 79 2.756e-14 2.918e-13
18 hsa04150_mTOR_signaling_pathway 9 52 2.979e-14 2.979e-13
19 hsa04012_ErbB_signaling_pathway 9 87 3.838e-12 3.636e-11
20 hsa04621_NOD.like_receptor_signaling_pathway 8 59 6.907e-12 6.216e-11
21 hsa04666_Fc_gamma_R.mediated_phagocytosis 9 95 8.635e-12 7.401e-11
22 hsa04630_Jak.STAT_signaling_pathway 10 155 2.646e-11 2.165e-10
23 hsa04960_Aldosterone.regulated_sodium_reabsorption 7 42 3.35e-11 2.621e-10
24 hsa04920_Adipocytokine_signaling_pathway 7 68 1.134e-09 8.508e-09
25 hsa04720_Long.term_potentiation 7 70 1.396e-09 1.005e-08
26 hsa04070_Phosphatidylinositol_signaling_system 7 78 3.022e-09 2.092e-08
27 hsa04114_Oocyte_meiosis 7 114 4.336e-08 2.89e-07
28 hsa04670_Leukocyte_transendothelial_migration 7 117 5.19e-08 3.336e-07
29 hsa04622_RIG.I.like_receptor_signaling_pathway 6 71 6.267e-08 3.89e-07
30 hsa04310_Wnt_signaling_pathway 7 151 2.987e-07 1.792e-06
31 hsa04020_Calcium_signaling_pathway 7 177 8.74e-07 5.075e-06
32 hsa04115_p53_signaling_pathway 5 69 1.828e-06 1.028e-05
33 hsa04810_Regulation_of_actin_cytoskeleton 7 214 3.098e-06 1.69e-05
34 hsa04623_Cytosolic_DNA.sensing_pathway 4 56 2.237e-05 0.0001184
35 hsa00562_Inositol_phosphate_metabolism 4 57 2.401e-05 0.0001235
36 hsa04360_Axon_guidance 5 130 4.059e-05 0.0002029
37 hsa04640_Hematopoietic_cell_lineage 4 88 0.0001324 0.0006441
38 hsa04962_Vasopressin.regulated_water_reabsorption 2 44 0.007475 0.03541
39 hsa04120_Ubiquitin_mediated_proteolysis 3 139 0.008041 0.03711
40 hsa04742_Taste_transduction 2 52 0.01032 0.04644
41 hsa04340_Hedgehog_signaling_pathway 2 56 0.0119 0.05223
42 hsa04141_Protein_processing_in_endoplasmic_reticulum 3 168 0.01342 0.05751
43 hsa04976_Bile_secretion 2 71 0.01866 0.07812
44 hsa04971_Gastric_acid_secretion 2 74 0.02017 0.08252
45 hsa04970_Salivary_secretion 2 89 0.02843 0.1136
46 hsa04540_Gap_junction 2 90 0.02903 0.1136
47 hsa04912_GnRH_signaling_pathway 2 101 0.03586 0.1345
48 hsa04916_Melanogenesis 2 101 0.03586 0.1345
49 hsa04270_Vascular_smooth_muscle_contraction 2 116 0.04606 0.1692
50 hsa04530_Tight_junction 2 133 0.05873 0.2114
51 hsa04740_Olfactory_transduction 2 388 0.3178 1

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1

TBX5-AS1

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-450b-5p;hsa-miR-590-5p;hsa-miR-629-3p 21 PIK3R1 Sponge network -2.108 0 -1.285 0 0.544
2

AC109642.1

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-93-5p;hsa-miR-96-5p 20 PIK3R1 Sponge network -2.791 0 -1.285 0 0.529
3

RP11-389C8.2

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 18 PIK3R1 Sponge network -2.039 0 -1.285 0 0.52
4

LINC00968

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 22 PIK3R1 Sponge network -4.19 0 -1.285 0 0.51
5 RP11-720L2.4 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-93-5p 13 PIK3R1 Sponge network -2.305 0 -1.285 0 0.496
6

LINC00702

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-582-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 26 PIK3R1 Sponge network -2.856 0 -1.285 0 0.494
7

MAGI2-AS3

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 22 PIK3R1 Sponge network -1.892 0 -1.285 0 0.486
8

LINC00702

hsa-miR-106b-5p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-362-5p;hsa-miR-93-5p 11 AKT3 Sponge network -2.856 0 -1.44 0 0.485
9 LINC00472 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-93-5p 15 PIK3R1 Sponge network -2.952 0 -1.285 0 0.458
10

FENDRR

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 19 PIK3R1 Sponge network -4.222 0 -1.285 0 0.438
11

AC007743.1

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-424-5p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 17 PIK3R1 Sponge network -2.595 0 -1.285 0 0.436
12 AF131215.2 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-589-3p 12 PIK3R1 Sponge network -2.09 0 -1.285 0 0.428
13

RP11-456K23.1

hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-224-5p;hsa-miR-29a-5p;hsa-miR-450b-5p;hsa-miR-542-3p;hsa-miR-590-3p;hsa-miR-590-5p 11 BCL2 Sponge network -1.488 0 -0.487 0.06421 0.423
14

RP11-1024P17.1

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-629-3p 18 PIK3R1 Sponge network -2.062 0 -1.285 0 0.418
15

RP11-400K9.4

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-29b-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -1.193 0.00359 -1.285 0 0.418
16 RP11-672A2.4 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-22-5p;hsa-miR-424-5p 12 PIK3R1 Sponge network -2.68 0 -1.285 0 0.417
17

RP11-456K23.1

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p 23 PIK3R1 Sponge network -1.488 0 -1.285 0 0.416
18

RP11-354E11.2

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-96-5p 18 PIK3R1 Sponge network -2.138 0 -1.285 0 0.41
19

RP11-401P9.4

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-590-5p;hsa-miR-93-5p 14 PIK3R1 Sponge network -3.04 0 -1.285 0 0.408
20

CTD-2013N24.2

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 20 PIK3R1 Sponge network -1.745 0 -1.285 0 0.407
21 RP11-532F6.3 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-590-3p;hsa-miR-629-3p 15 PIK3R1 Sponge network -2.028 0 -1.285 0 0.395
22

MIR497HG

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-589-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 23 PIK3R1 Sponge network -2.142 0 -1.285 0 0.391
23

RP11-456K23.1

hsa-miR-106b-5p;hsa-miR-146b-5p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-22-3p;hsa-miR-28-3p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-362-5p;hsa-miR-542-3p;hsa-miR-93-5p 14 AKT3 Sponge network -1.488 0 -1.44 0 0.389
24

TBX5-AS1

hsa-miR-106b-5p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-28-3p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-362-5p;hsa-miR-542-3p 12 AKT3 Sponge network -2.108 0 -1.44 0 0.386
25

MAGI2-AS3

hsa-miR-106b-5p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-362-5p;hsa-miR-93-5p 11 AKT3 Sponge network -1.892 0 -1.44 0 0.386
26

RP11-399O19.9

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-93-5p 12 PIK3R1 Sponge network -0.873 0.00072 -1.285 0 0.38
27 FGF14-AS2 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-96-5p 12 PIK3R1 Sponge network -2.159 0 -1.285 0 0.378
28 HHIP-AS1 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-590-3p 15 PIK3R1 Sponge network -2.807 0 -1.285 0 0.374
29 LINC00092 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-424-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-629-3p 14 PIK3R1 Sponge network -2.383 0 -1.285 0 0.369
30

RP11-378A13.1

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 17 PIK3R1 Sponge network -1.713 0 -1.285 0 0.367
31

CTD-2013N24.2

hsa-miR-106b-5p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-181b-5p;hsa-miR-20a-5p;hsa-miR-22-3p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-362-5p;hsa-miR-93-5p 13 AKT3 Sponge network -1.745 0 -1.44 0 0.366
32 SH3RF3-AS1 hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-582-5p;hsa-miR-590-5p 15 PIK3R1 Sponge network -1.583 0 -1.285 0 0.364
33

AC011899.9

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-590-3p 16 PIK3R1 Sponge network -2.611 0 -1.285 0 0.364
34 AC079630.4 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-424-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -3.758 0 -1.285 0 0.359
35 RP5-1042I8.7 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 14 PIK3R1 Sponge network -0.733 0.00018 -1.285 0 0.358
36 AC003090.1 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-424-5p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 17 PIK3R1 Sponge network -3.16 2.0E-5 -1.285 0 0.358
37

GAS6-AS2

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-335-3p;hsa-miR-590-5p 17 PIK3R1 Sponge network -1.761 0 -1.285 0 0.354
38

MAGI2-AS3

hsa-miR-141-3p;hsa-miR-20a-3p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-324-5p;hsa-miR-335-3p;hsa-miR-33a-5p;hsa-miR-421;hsa-miR-501-5p;hsa-miR-589-3p;hsa-miR-660-5p 11 IRAK3 Sponge network -1.892 0 -1.317 1.0E-5 0.348
39 LINC00961 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-424-5p;hsa-miR-589-3p;hsa-miR-96-5p 15 PIK3R1 Sponge network -2.724 0 -1.285 0 0.346
40 RBMS3-AS3 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-22-5p;hsa-miR-629-3p;hsa-miR-96-5p 11 PIK3R1 Sponge network -2.307 0.0011 -1.285 0 0.345
41 AC010226.4 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-22-5p;hsa-miR-93-5p 10 PIK3R1 Sponge network -1.081 2.0E-5 -1.285 0 0.344
42

AC003991.3

hsa-miR-130a-3p;hsa-miR-130b-3p;hsa-miR-16-1-3p;hsa-miR-193a-3p;hsa-miR-193b-3p;hsa-miR-19a-3p;hsa-miR-20a-3p;hsa-miR-26b-3p;hsa-miR-301a-3p;hsa-miR-335-3p;hsa-miR-590-3p 11 ENDOD1 Sponge network -0.787 0.08132 0.057 0.80229 0.343
43 LINC00987 hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-93-5p;hsa-miR-96-5p 10 PIK3R1 Sponge network -0.927 0 -1.285 0 0.343
44 BZRAP1-AS1 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -0.785 0.00723 -1.285 0 0.34
45 AC011526.1 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-590-3p;hsa-miR-93-5p;hsa-miR-96-5p 13 PIK3R1 Sponge network -2.783 0 -1.285 0 0.338
46

AC004947.2

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-450b-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p 17 PIK3R1 Sponge network -3.94 0 -1.285 0 0.332
47 CTC-523E23.4 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-590-3p 11 PIK3R1 Sponge network -1.636 0.00051 -1.285 0 0.33
48

WDFY3-AS2

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-96-5p 18 PIK3R1 Sponge network -1.297 0 -1.285 0 0.329
49 CTD-2003C8.2 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-590-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -3.403 0 -1.285 0 0.328
50 LINC00883 hsa-miR-107;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-629-3p 12 PIK3R1 Sponge network -1.466 0 -1.285 0 0.327
51 RP11-293M10.6 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-590-5p;hsa-miR-93-5p 10 PIK3R1 Sponge network -1.199 0.00063 -1.285 0 0.32
52

RP11-354E11.2

hsa-miR-130b-3p;hsa-miR-16-1-3p;hsa-miR-193a-3p;hsa-miR-193b-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-26b-3p;hsa-miR-301a-3p;hsa-miR-330-5p;hsa-miR-335-3p;hsa-miR-590-3p 12 ENDOD1 Sponge network -2.138 0 0.057 0.80229 0.32
53 RP11-434D9.1 hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-590-3p;hsa-miR-629-3p 11 PIK3R1 Sponge network -4.573 0 -1.285 0 0.319
54

NR2F1-AS1

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-29b-3p;hsa-miR-335-3p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 18 PIK3R1 Sponge network -0.427 0.1559 -1.285 0 0.318
55 CTC-559E9.4 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-590-5p;hsa-miR-93-5p 10 PIK3R1 Sponge network -0.737 0.0562 -1.285 0 0.318
56 RP11-789C1.1 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-93-5p 10 PIK3R1 Sponge network -4.664 0.00012 -1.285 0 0.317
57 LINC00607 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-335-3p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p 15 PIK3R1 Sponge network -2.277 0 -1.285 0 0.316
58 RP11-517P14.2 hsa-miR-106b-5p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-590-3p;hsa-miR-93-5p 10 PIK3R1 Sponge network -0.795 6.0E-5 -1.285 0 0.315
59 RP4-639F20.1 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-22-5p;hsa-miR-96-5p 11 PIK3R1 Sponge network -1.312 0 -1.285 0 0.314
60 RP11-244O19.1 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 11 PIK3R1 Sponge network -0.428 0.21699 -1.285 0 0.303
61

RP11-462G12.1

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-93-5p 15 PIK3R1 Sponge network -1.071 0.01175 -1.285 0 0.302
62 LINC01088 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -1.385 0.01604 -1.285 0 0.3
63 AC016735.2 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-21-5p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-582-5p;hsa-miR-96-5p 11 PIK3R1 Sponge network -2.711 0.00282 -1.285 0 0.298
64 RP11-67L2.2 hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-93-5p;hsa-miR-96-5p 11 PIK3R1 Sponge network -1.062 0 -1.285 0 0.298
65

TBX5-AS1

hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-24-2-5p;hsa-miR-29a-5p;hsa-miR-365a-3p;hsa-miR-450b-5p;hsa-miR-542-3p;hsa-miR-590-5p 12 BCL2 Sponge network -2.108 0 -0.487 0.06421 0.297
66

LINC00702

hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-29a-5p;hsa-miR-34a-5p;hsa-miR-450b-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-96-5p 12 BCL2 Sponge network -2.856 0 -0.487 0.06421 0.297
67 RP11-88I21.2 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 13 PIK3R1 Sponge network -8.789 0 -1.285 0 0.297
68 RP11-1008C21.2 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-629-3p;hsa-miR-93-5p 15 PIK3R1 Sponge network -1.249 0 -1.285 0 0.297
69 AC034187.2 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -1.974 0 -1.285 0 0.297
70 RP11-365O16.3 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-93-5p 12 PIK3R1 Sponge network -2.765 0.00017 -1.285 0 0.293
71

FENDRR

hsa-miR-141-3p;hsa-miR-20a-3p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-3200-3p;hsa-miR-324-5p;hsa-miR-335-3p;hsa-miR-33a-5p;hsa-miR-421;hsa-miR-450b-5p 10 IRAK3 Sponge network -4.222 0 -1.317 1.0E-5 0.291
72

CASC2

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p 15 PIK3R1 Sponge network -1.086 0 -1.285 0 0.29
73

LINC00702

hsa-miR-141-3p;hsa-miR-20a-3p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-335-3p;hsa-miR-33a-5p;hsa-miR-421;hsa-miR-450b-5p;hsa-miR-501-5p;hsa-miR-589-3p;hsa-miR-590-5p;hsa-miR-660-5p 12 IRAK3 Sponge network -2.856 0 -1.317 1.0E-5 0.285
74

RP11-284N8.3

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 18 PIK3R1 Sponge network -0.761 0.05061 -1.285 0 0.285
75 AF131215.9 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-21-5p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-589-3p;hsa-miR-590-3p 12 PIK3R1 Sponge network -1.808 0 -1.285 0 0.282
76 RP11-352D13.6 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-424-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p;hsa-miR-96-5p 15 PIK3R1 Sponge network -4.634 0 -1.285 0 0.28
77 LIPE-AS1 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-590-5p;hsa-miR-93-5p 14 PIK3R1 Sponge network -0.734 0.00039 -1.285 0 0.28
78 RP11-476D10.1 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-96-5p 13 PIK3R1 Sponge network -4.519 0 -1.285 0 0.279
79 BDNF-AS hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 13 PIK3R1 Sponge network -0.568 0.02011 -1.285 0 0.277
80 CTD-2135D7.5 hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-590-5p;hsa-miR-629-3p 11 PIK3R1 Sponge network -3.162 0 -1.285 0 0.277
81 CTC-441N14.2 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-582-5p;hsa-miR-96-5p 12 PIK3R1 Sponge network -2.273 0.01231 -1.285 0 0.276
82 LINC00443 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-15a-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p 14 PIK3R1 Sponge network -3.704 0.0003 -1.285 0 0.276
83 AC008268.1 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-629-3p;hsa-miR-93-5p 10 PIK3R1 Sponge network -5.661 0 -1.285 0 0.276
84

RP11-1008C21.1

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-629-3p 13 PIK3R1 Sponge network -1.826 3.0E-5 -1.285 0 0.272
85 SNHG18 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -1.073 0.00533 -1.285 0 0.27
86 C1orf132 hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-450b-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -0.86 0.02429 -1.285 0 0.269
87 LINC00551 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-424-5p;hsa-miR-629-3p;hsa-miR-96-5p 10 PIK3R1 Sponge network -2.179 0.00466 -1.285 0 0.269
88

TBX5-AS1

hsa-miR-141-3p;hsa-miR-20a-3p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-3200-3p;hsa-miR-324-5p;hsa-miR-335-3p;hsa-miR-33a-5p;hsa-miR-421;hsa-miR-450b-5p;hsa-miR-501-5p;hsa-miR-590-5p 12 IRAK3 Sponge network -2.108 0 -1.317 1.0E-5 0.267
89 LINC01024 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-93-5p 11 PIK3R1 Sponge network -0.659 0.02711 -1.285 0 0.266
90 CTC-366B18.4 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-93-5p 10 PIK3R1 Sponge network -0.652 0.01265 -1.285 0 0.265
91

NR2F1-AS1

hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-582-5p;hsa-miR-7-1-3p;hsa-miR-93-5p 10 IL1RAP Sponge network -0.427 0.1559 0 0.99919 0.265
92 RP1-78O14.1 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-629-3p 11 PIK3R1 Sponge network -4.409 0 -1.285 0 0.264
93 AC096670.3 hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-424-5p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 11 PIK3R1 Sponge network -1.939 7.0E-5 -1.285 0 0.263
94

AC007743.1

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-142-5p;hsa-miR-148a-3p;hsa-miR-155-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-29a-5p;hsa-miR-590-5p 11 PRKAR2A Sponge network -2.595 0 -0.542 0.00821 0.263
95 RP5-839B4.8 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-629-3p;hsa-miR-93-5p 14 PIK3R1 Sponge network -5.037 0 -1.285 0 0.262
96 DIO3OS hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-424-5p;hsa-miR-589-3p;hsa-miR-629-3p 14 PIK3R1 Sponge network -1.936 0.00085 -1.285 0 0.262
97 CTC-523E23.1 hsa-miR-106b-5p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-590-3p;hsa-miR-629-3p 10 PIK3R1 Sponge network -1.223 0.0005 -1.285 0 0.262
98 RP4-668J24.2 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-1301-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-629-3p 11 PIK3R1 Sponge network -2.397 0.00331 -1.285 0 0.261
99 RP11-347J14.7 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-96-5p 10 PIK3R1 Sponge network -5.394 0 -1.285 0 0.261
100

LINC00261

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p 17 PIK3R1 Sponge network -2.566 0.00025 -1.285 0 0.259
101 AGAP11 hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-21-5p;hsa-miR-424-5p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p 10 PIK3R1 Sponge network -2.127 0 -1.285 0 0.255
102 LINC00619 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p 11 PIK3R1 Sponge network -2.307 0.02217 -1.285 0 0.255
103

DNM3OS

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-93-5p 16 PIK3R1 Sponge network 0.053 0.85755 -1.285 0 0.255
104 CTA-221G9.11 hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-128-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-93-5p 13 PIK3R1 Sponge network -0.645 0.06404 -1.285 0 0.254
105

PCED1B-AS1

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-335-3p;hsa-miR-93-5p;hsa-miR-96-5p 12 PIK3R1 Sponge network -0.672 0.02084 -1.285 0 0.254
106 RP11-677M14.3 hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-424-5p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p 10 PIK3R1 Sponge network -1.866 0 -1.285 0 0.251
107

MIR497HG

hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-29a-5p;hsa-miR-450b-5p;hsa-miR-590-5p;hsa-miR-96-5p 10 BCL2 Sponge network -2.142 0 -0.487 0.06421 0.251

Quest ID: 7292952ebe7bfb89ca9d4aabaee68f44