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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-182-5p AASS 3.54 0 -1.35 5.0E-5 MirTarget -0.12 0.00483 NA
2 hsa-miR-182-5p AATK 3.54 0 -0.62 0.02571 MirTarget -0.11 0.00069 NA
3 hsa-miR-27a-3p ABAT 1.67 0 -0.34 0.43051 MirTarget -0.21 0.01964 NA
4 hsa-miR-421 ABAT 1.18 1.0E-5 -0.34 0.43051 PITA; miRanda; miRNATAP -0.19 0.01702 NA
5 hsa-miR-106b-5p ABCA1 2.47 0 -0.71 0.00276 MirTarget; miRNATAP -0.21 0 NA
6 hsa-miR-301a-3p ABCA1 2.81 0 -0.71 0.00276 miRNATAP -0.18 0 NA
7 hsa-miR-421 ABCA6 1.18 1.0E-5 -2.84 1.0E-5 miRanda -0.23 0.04461 NA
8 hsa-miR-421 ABCB1 1.18 1.0E-5 -2.33 0 miRanda -0.28 3.0E-5 NA
9 hsa-miR-421 ABCB4 1.18 1.0E-5 -1.92 0 miRanda -0.31 0 NA
10 hsa-miR-132-3p ABCC5 0.16 0.40819 0.08 0.78106 mirMAP -0.35 0 NA
11 hsa-miR-212-3p ABCC5 0.36 0.23245 0.08 0.78106 mirMAP -0.22 0 NA
12 hsa-miR-106b-5p ABCD2 2.47 0 -3.08 0 MirTarget -0.8 0 NA
13 hsa-miR-421 ABCD2 1.18 1.0E-5 -3.08 0 miRanda -0.3 0.00068 NA
14 hsa-miR-132-3p ABCG1 0.16 0.40819 -0.08 0.79796 MirTarget -0.25 0.00084 NA
15 hsa-miR-212-3p ABCG1 0.36 0.23245 -0.08 0.79796 MirTarget -0.17 0.00051 NA
16 hsa-miR-25-3p ABHD13 1.36 0 -0.35 0.00167 miRNATAP -0.12 0 NA
17 hsa-miR-106b-5p ABHD2 2.47 0 -0.37 0.12248 miRNATAP -0.13 0.00297 NA
18 hsa-miR-27a-3p ABHD2 1.67 0 -0.37 0.12248 mirMAP -0.15 0.00323 NA
19 hsa-miR-301a-3p ABHD2 2.81 0 -0.37 0.12248 mirMAP -0.12 0.00066 NA
20 hsa-miR-27a-3p ABI2 1.67 0 -0.65 0 mirMAP -0.13 0 NA
21 hsa-miR-421 ABI3BP 1.18 1.0E-5 -4.28 0 miRanda -0.63 0 NA
22 hsa-miR-106b-5p ABL2 2.47 0 -0.32 0.04554 MirTarget -0.13 1.0E-5 NA
23 hsa-miR-182-5p ABL2 3.54 0 -0.32 0.04554 mirMAP -0.14 0 NA
24 hsa-miR-25-3p ABLIM1 1.36 0 -1.72 0 mirMAP -0.2 0.00211 NA
25 hsa-miR-421 ABLIM1 1.18 1.0E-5 -1.72 0 miRanda -0.19 0.00017 NA
26 hsa-miR-940 ABLIM2 3.21 0 -1.01 0.01362 MirTarget -0.27 0 NA
27 hsa-miR-106b-5p ABTB2 2.47 0 0.07 0.80766 miRNAWalker2 validate -0.14 0.0131 NA
28 hsa-miR-27a-3p ACE 1.67 0 -0.35 0.17613 mirMAP -0.16 0.00344 NA
29 hsa-miR-421 ACE2 1.18 1.0E-5 -0.56 0.35375 miRanda -0.38 0.00058 NA
30 hsa-miR-25-3p ACTC1 1.36 0 -7.19 0 MirTarget -2.06 0 NA
31 hsa-miR-218-5p ACTN1 -0.57 0.0552 -1.05 0.00011 miRNAWalker2 validate; miRNATAP -0.1 0.02025 NA
32 hsa-miR-421 ACTN1 1.18 1.0E-5 -1.05 0.00011 miRanda -0.22 1.0E-5 NA
33 hsa-miR-421 ACTN2 1.18 1.0E-5 -3.37 0 miRanda -0.24 0.03335 NA
34 hsa-miR-182-5p ACVR1 3.54 0 -0.44 0.01143 MirTarget; miRNATAP -0.15 0 NA
35 hsa-miR-301a-3p ACVR1 2.81 0 -0.44 0.01143 MirTarget; miRNATAP -0.21 0 NA
36 hsa-miR-27a-3p ACVR2A 1.67 0 -0.44 0.02646 miRNATAP -0.28 0 NA
37 hsa-miR-182-5p ACVRL1 3.54 0 -1.25 0 mirMAP -0.25 0 NA
38 hsa-miR-301a-3p ACVRL1 2.81 0 -1.25 0 mirMAP -0.28 0 NA
39 hsa-miR-940 ACVRL1 3.21 0 -1.25 0 mirMAP -0.23 0 NA
40 hsa-miR-301a-3p ADAM12 2.81 0 0.88 0.05623 miRNATAP -0.39 0 NA
41 hsa-miR-421 ADAM12 1.18 1.0E-5 0.88 0.05623 mirMAP; miRNATAP -0.27 0.0013 NA
42 hsa-miR-106b-5p ADAM19 2.47 0 -1.06 0.01895 mirMAP -0.7 0 NA
43 hsa-miR-182-5p ADAM19 3.54 0 -1.06 0.01895 miRNATAP -0.53 0 NA
44 hsa-miR-25-3p ADAM19 1.36 0 -1.06 0.01895 MirTarget; miRNATAP -0.63 0 NA
45 hsa-miR-421 ADAM19 1.18 1.0E-5 -1.06 0.01895 mirMAP -0.3 0.00037 NA
46 hsa-miR-940 ADAM19 3.21 0 -1.06 0.01895 MirTarget -0.43 0 NA
47 hsa-miR-106b-5p ADAM9 2.47 0 -0.2 0.40665 miRNATAP -0.3 0 NA
48 hsa-miR-27a-3p ADAMTS10 1.67 0 -1.26 0.00027 MirTarget; miRNATAP -0.17 0.01739 NA
49 hsa-miR-940 ADAMTS14 3.21 0 0.61 0.12479 mirMAP -0.29 0 NA
50 hsa-miR-182-5p ADAMTS18 3.54 0 -0.74 0.14599 miRNATAP -0.22 0.00048 NA
51 hsa-miR-301a-3p ADAMTS18 2.81 0 -0.74 0.14599 miRNATAP -0.32 2.0E-5 NA
52 hsa-miR-421 ADAMTS18 1.18 1.0E-5 -0.74 0.14599 miRanda; miRNATAP -0.2 0.03763 NA
53 hsa-miR-182-5p ADAMTS4 3.54 0 -2.17 0 MirTarget -0.42 0 NA
54 hsa-miR-940 ADAMTS4 3.21 0 -2.17 0 MirTarget -0.36 0 NA
55 hsa-miR-106b-5p ADAMTS5 2.47 0 -2.16 0 miRNATAP -0.52 0 NA
56 hsa-miR-421 ADAMTS5 1.18 1.0E-5 -2.16 0 mirMAP -0.22 0.00033 NA
57 hsa-miR-25-3p ADAMTSL1 1.36 0 -2.52 0 miRNAWalker2 validate; miRNATAP -0.5 0 NA
58 hsa-miR-27a-3p ADAMTSL1 1.67 0 -2.52 0 miRNATAP -0.4 3.0E-5 NA
59 hsa-miR-421 ADAMTSL1 1.18 1.0E-5 -2.52 0 miRanda -0.35 4.0E-5 NA
60 hsa-miR-25-3p ADAMTSL3 1.36 0 -5.11 0 MirTarget; miRNATAP -0.96 0 NA
61 hsa-miR-27a-3p ADAMTSL3 1.67 0 -5.11 0 miRNATAP -0.75 0 NA
62 hsa-miR-940 ADAMTSL4 3.21 0 -1.86 9.0E-5 MirTarget -0.39 0 NA
63 hsa-miR-106b-5p ADARB1 2.47 0 -1.93 0 MirTarget -0.54 0 NA
64 hsa-miR-182-5p ADCY2 3.54 0 -3.87 0 miRNATAP -0.4 0 NA
65 hsa-miR-301a-3p ADCY2 2.81 0 -3.87 0 miRNATAP -0.6 0 NA
66 hsa-miR-421 ADCY2 1.18 1.0E-5 -3.87 0 miRanda -0.48 1.0E-5 NA
67 hsa-miR-27a-3p ADCY6 1.67 0 -0.13 0.52489 MirTarget; miRNATAP -0.22 0 NA
68 hsa-miR-106b-5p ADCY9 2.47 0 -1.5 0 mirMAP -0.51 0 NA
69 hsa-miR-25-3p ADCY9 1.36 0 -1.5 0 mirMAP -0.48 0 NA
70 hsa-miR-27a-3p ADD1 1.67 0 -0.81 0 MirTarget -0.15 0 NA
71 hsa-miR-27a-3p ADD3 1.67 0 -0.66 0.00185 miRNATAP -0.17 5.0E-5 NA
72 hsa-miR-940 ADIPOQ 3.21 0 -5.02 0 MirTarget -0.85 0 NA
73 hsa-miR-218-5p ADIPOR2 -0.57 0.0552 0.21 0.11195 MirTarget; miRNATAP -0.11 0 NA
74 hsa-miR-25-3p ADM 1.36 0 -0.13 0.70322 miRNATAP -0.32 5.0E-5 NA
75 hsa-miR-421 ADORA3 1.18 1.0E-5 -0.39 0.2849 miRanda -0.32 0 NA
76 hsa-miR-106b-5p ADRA2A 2.47 0 -2.58 0 miRNATAP -0.65 0 NA
77 hsa-miR-421 ADRB3 1.18 1.0E-5 -5.02 0 miRanda -0.79 0 NA
78 hsa-miR-182-5p AFAP1 3.54 0 -0.98 0.00012 mirMAP -0.26 0 NA
79 hsa-miR-132-3p AFF1 0.16 0.40819 -0.53 0.00163 mirMAP -0.15 0.00095 NA
80 hsa-miR-182-5p AFF2 3.54 0 -1.73 0.00201 mirMAP -0.22 0.00162 NA
81 hsa-miR-27a-3p AFF2 1.67 0 -1.73 0.00201 mirMAP -0.33 0.00415 NA
82 hsa-miR-940 AFF2 3.21 0 -1.73 0.00201 miRNATAP -0.19 0.00572 NA
83 hsa-miR-25-3p AFF3 1.36 0 -5 0 MirTarget -0.75 0 NA
84 hsa-miR-27a-3p AFF3 1.67 0 -5 0 mirMAP -0.9 0 NA
85 hsa-miR-421 AFF3 1.18 1.0E-5 -5 0 PITA; miRanda; miRNATAP -0.56 0 NA
86 hsa-miR-106b-5p AFF4 2.47 0 -0.82 0 miRNATAP -0.11 0.00011 NA
87 hsa-miR-25-3p AFF4 1.36 0 -0.82 0 mirMAP; miRNATAP -0.13 0.00014 NA
88 hsa-miR-106b-5p AGFG1 2.47 0 -0.17 0.30925 MirTarget -0.15 0 NA
89 hsa-miR-301a-3p AGFG1 2.81 0 -0.17 0.30925 MirTarget; miRNATAP -0.12 0 NA
90 hsa-miR-421 AGFG2 1.18 1.0E-5 -0.51 0.00539 mirMAP -0.17 0 NA
91 hsa-miR-301a-3p AGPAT4 2.81 0 -0.79 0.01174 mirMAP -0.2 2.0E-5 NA
92 hsa-miR-421 AGT 1.18 1.0E-5 -1.62 0.00168 miRanda -0.21 0.02951 NA
93 hsa-miR-106b-5p AHNAK 2.47 0 -1.66 0 miRNATAP -0.55 0 NA
94 hsa-miR-421 AHNAK 1.18 1.0E-5 -1.66 0 miRNAWalker2 validate -0.3 0 NA
95 hsa-miR-25-3p AIDA 1.36 0 -0.31 0.01307 MirTarget; miRNATAP -0.16 0 NA
96 hsa-miR-182-5p AK5 3.54 0 -1.18 0.03248 MirTarget -0.16 0.02037 NA
97 hsa-miR-106b-5p AKAP11 2.47 0 -0.8 0 miRNAWalker2 validate -0.18 0 NA
98 hsa-miR-25-3p AKAP12 1.36 0 -2.95 0 mirMAP -0.27 0.0072 NA
99 hsa-miR-106b-5p AKAP13 2.47 0 -1.15 0 MirTarget; mirMAP; miRNATAP -0.34 0 NA
100 hsa-miR-421 AKAP13 1.18 1.0E-5 -1.15 0 miRanda -0.21 0 NA
101 hsa-miR-421 AKAP2 1.18 1.0E-5 -2.51 8.0E-5 miRanda -0.3 0.01231 NA
102 hsa-miR-421 AKAP6 1.18 1.0E-5 -3.34 0 miRanda -0.4 0 NA
103 hsa-miR-182-5p AKAP7 3.54 0 -1.26 1.0E-5 miRNATAP -0.14 6.0E-5 NA
104 hsa-miR-301a-3p AKNA 2.81 0 -0.9 2.0E-5 mirMAP -0.17 0 NA
105 hsa-miR-940 AKNA 3.21 0 -0.9 2.0E-5 miRNATAP -0.17 0 NA
106 hsa-miR-106b-5p AKT3 2.47 0 -1.94 0 miRNATAP -0.52 0 NA
107 hsa-miR-421 AKT3 1.18 1.0E-5 -1.94 0 miRanda; mirMAP -0.27 4.0E-5 NA
108 hsa-miR-25-3p ALDH1L2 1.36 0 -1.12 0.02448 mirMAP -0.56 0 NA
109 hsa-miR-106b-5p ALDH3A2 2.47 0 -0.63 0.00987 mirMAP -0.16 0.00048 NA
110 hsa-miR-940 ALDH3B1 3.21 0 -0.69 0.04575 MirTarget -0.19 1.0E-5 NA
111 hsa-miR-25-3p ALDH7A1 1.36 0 -1.69 0.00179 mirMAP -0.44 0.00041 NA
112 hsa-miR-27a-3p ALDH9A1 1.67 0 -0.61 2.0E-5 miRNAWalker2 validate -0.17 0 NA
113 hsa-miR-421 ALPK1 1.18 1.0E-5 -0.12 0.52034 miRanda -0.12 0.00046 NA
114 hsa-miR-421 ALPK2 1.18 1.0E-5 0.09 0.88185 miRanda -0.25 0.01743 NA
115 hsa-miR-106b-5p ALPK3 2.47 0 -1.02 0.00049 mirMAP -0.3 0 NA
116 hsa-miR-301a-3p ALPK3 2.81 0 -1.02 0.00049 mirMAP -0.21 0 NA
117 hsa-miR-218-5p AMOTL1 -0.57 0.0552 -1.62 0 mirMAP -0.11 0.02064 NA
118 hsa-miR-301a-3p AMOTL1 2.81 0 -1.62 0 mirMAP -0.24 0 NA
119 hsa-miR-182-5p AMOTL2 3.54 0 -1.01 0.00015 miRNATAP -0.24 0 NA
120 hsa-miR-421 ANG 1.18 1.0E-5 -1.34 0 miRanda -0.25 0 NA
121 hsa-miR-421 ANGPTL1 1.18 1.0E-5 -4.51 0 miRanda -0.69 0 NA
122 hsa-miR-940 ANK1 3.21 0 -0.47 0.3186 MirTarget; PITA; miRNATAP -0.14 0.01383 NA
123 hsa-miR-106b-5p ANK2 2.47 0 -4.32 0 MirTarget; miRNATAP -0.94 0 NA
124 hsa-miR-182-5p ANK2 3.54 0 -4.32 0 miRNATAP -0.75 0 NA
125 hsa-miR-27a-3p ANK2 1.67 0 -4.32 0 MirTarget; miRNATAP -0.64 0 NA
126 hsa-miR-421 ANK3 1.18 1.0E-5 -0.29 0.31896 miRanda -0.11 0.04758 NA
127 hsa-miR-106b-5p ANKH 2.47 0 -0.38 0.21654 MirTarget -0.43 0 NA
128 hsa-miR-421 ANKH 1.18 1.0E-5 -0.38 0.21654 miRanda -0.3 0 NA
129 hsa-miR-27a-3p ANKRD27 1.67 0 -0.2 0.19566 MirTarget -0.1 0.00116 NA
130 hsa-miR-106b-5p ANKRD29 2.47 0 -3.47 0 MirTarget -1.13 0 NA
131 hsa-miR-27a-3p ANKRD40 1.67 0 -0.42 9.0E-5 MirTarget -0.12 0 NA
132 hsa-miR-421 ANKRD44 1.18 1.0E-5 -1.93 0 miRanda -0.22 0.00089 NA
133 hsa-miR-106b-5p ANKRD50 2.47 0 -0.88 0.00174 MirTarget; miRNATAP -0.2 0.00016 NA
134 hsa-miR-421 ANKRD50 1.18 1.0E-5 -0.88 0.00174 MirTarget; PITA; miRanda; miRNATAP -0.15 0.00319 NA
135 hsa-miR-27a-3p ANKS1A 1.67 0 -0.38 0.09203 MirTarget -0.27 0 NA
136 hsa-miR-421 ANKS1B 1.18 1.0E-5 -3.65 0 miRanda; miRNATAP -0.25 0.00908 NA
137 hsa-miR-106b-5p ANO6 2.47 0 -0.74 3.0E-5 MirTarget -0.13 0.00012 NA
138 hsa-miR-421 ANTXR1 1.18 1.0E-5 -0.71 0.0159 miRanda -0.31 0 NA
139 hsa-miR-182-5p ANTXR2 3.54 0 -2.31 0 miRNATAP -0.45 0 NA
140 hsa-miR-27a-3p ANTXR2 1.67 0 -2.31 0 miRNATAP -0.28 3.0E-5 NA
141 hsa-miR-940 ANTXR2 3.21 0 -2.31 0 miRNATAP -0.4 0 NA
142 hsa-miR-106b-5p ANXA11 2.47 0 -0.43 0.01849 mirMAP -0.15 0 NA
143 hsa-miR-25-3p ANXA11 1.36 0 -0.43 0.01849 miRNAWalker2 validate -0.2 0 NA
144 hsa-miR-940 AOC3 3.21 0 -3.69 0 MirTarget -0.51 0 NA
145 hsa-miR-421 AP1S2 1.18 1.0E-5 -1.31 0 miRanda -0.13 0.00236 NA
146 hsa-miR-940 APBB1 3.21 0 -2.48 0 miRNATAP -0.31 0 NA
147 hsa-miR-106b-5p APBB2 2.47 0 -0.59 0.0014 MirTarget; miRNATAP -0.3 0 NA
148 hsa-miR-301a-3p APBB2 2.81 0 -0.59 0.0014 mirMAP -0.16 0 NA
149 hsa-miR-421 APBB2 1.18 1.0E-5 -0.59 0.0014 mirMAP; miRNATAP -0.12 0.0006 NA
150 hsa-miR-106b-5p APCDD1 2.47 0 -1.6 0 MirTarget -0.17 0.00845 NA
NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 376 1672 2.262e-47 1.052e-43
2 REGULATION OF CELL DIFFERENTIATION 346 1492 1.652e-46 3.842e-43
3 CARDIOVASCULAR SYSTEM DEVELOPMENT 215 788 1.447e-39 1.684e-36
4 CIRCULATORY SYSTEM DEVELOPMENT 215 788 1.447e-39 1.684e-36
5 CELL DEVELOPMENT 318 1426 6.819e-39 6.346e-36
6 TISSUE DEVELOPMENT 327 1518 7.79e-37 6.041e-34
7 REGULATION OF CELLULAR COMPONENT MOVEMENT 203 771 6.028e-35 4.007e-32
8 REGULATION OF CELL DEVELOPMENT 212 836 6.295e-34 3.661e-31
9 NEUROGENESIS 301 1402 1.651e-33 8.534e-31
10 VASCULATURE DEVELOPMENT 143 469 5.45e-32 2.536e-29
11 LOCOMOTION 250 1114 8.086e-31 3.42e-28
12 BIOLOGICAL ADHESION 236 1032 2.333e-30 9.045e-28
13 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 330 1656 2.578e-30 9.226e-28
14 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 234 1021 2.996e-30 9.956e-28
15 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 273 1275 4.149e-30 1.287e-27
16 BLOOD VESSEL MORPHOGENESIS 118 364 3.118e-29 9.066e-27
17 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 250 1142 4.579e-29 1.253e-26
18 INTRACELLULAR SIGNAL TRANSDUCTION 313 1572 1.257e-28 3.241e-26
19 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 228 1008 1.324e-28 3.241e-26
20 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 223 983 3.633e-28 8.452e-26
21 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 285 1395 6.952e-28 1.54e-25
22 RESPONSE TO ENDOGENOUS STIMULUS 293 1450 7.503e-28 1.587e-25
23 POSITIVE REGULATION OF RESPONSE TO STIMULUS 358 1929 9.489e-27 1.92e-24
24 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 190 801 1.612e-26 3.126e-24
25 REGULATION OF NEURON DIFFERENTIATION 148 554 2.584e-26 4.809e-24
26 POSITIVE REGULATION OF CELL DIFFERENTIATION 191 823 2.006e-25 3.59e-23
27 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 342 1848 2.841e-25 4.896e-23
28 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 271 1360 9.279e-25 1.542e-22
29 CELL MOTILITY 191 835 1.273e-24 1.974e-22
30 LOCALIZATION OF CELL 191 835 1.273e-24 1.974e-22
31 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 210 957 1.458e-24 2.188e-22
32 REGULATION OF CELL PROLIFERATION 290 1496 1.558e-24 2.266e-22
33 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 177 750 1.791e-24 2.525e-22
34 HEART DEVELOPMENT 127 466 1.503e-23 2.056e-21
35 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 326 1784 4.259e-23 5.662e-21
36 ORGAN MORPHOGENESIS 188 841 5.182e-23 6.697e-21
37 ANGIOGENESIS 93 293 1.519e-22 1.911e-20
38 REGULATION OF PHOSPHORUS METABOLIC PROCESS 301 1618 1.597e-22 1.955e-20
39 POSITIVE REGULATION OF CELL COMMUNICATION 288 1532 3.06e-22 3.651e-20
40 POSITIVE REGULATION OF GENE EXPRESSION 316 1733 3.245e-22 3.775e-20
41 REGULATION OF CELL ADHESION 152 629 3.369e-22 3.823e-20
42 MUSCLE STRUCTURE DEVELOPMENT 118 432 4.804e-22 5.322e-20
43 SKELETAL SYSTEM DEVELOPMENT 122 455 5.237e-22 5.667e-20
44 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 132 513 5.724e-22 6.053e-20
45 NEGATIVE REGULATION OF CELL DIFFERENTIATION 148 609 6.85e-22 7.083e-20
46 POSITIVE REGULATION OF LOCOMOTION 115 420 1.321e-21 1.336e-19
47 NEURON DIFFERENTIATION 189 874 2.144e-21 2.123e-19
48 REGULATION OF PROTEIN MODIFICATION PROCESS 310 1710 2.23e-21 2.162e-19
49 PROTEIN PHOSPHORYLATION 197 944 2.109e-20 1.966e-18
50 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 206 1004 2.113e-20 1.966e-18
51 NEGATIVE REGULATION OF CELL COMMUNICATION 233 1192 3.483e-20 3.178e-18
52 CELLULAR COMPONENT MORPHOGENESIS 189 900 6.53e-20 5.843e-18
53 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 156 689 8.706e-20 7.643e-18
54 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 172 799 2.522e-19 2.173e-17
55 REGULATION OF CELL DEATH 270 1472 2.577e-19 2.18e-17
56 MUSCLE TISSUE DEVELOPMENT 84 275 2.635e-19 2.19e-17
57 REGULATION OF NEURON PROJECTION DEVELOPMENT 108 408 3.684e-19 3.007e-17
58 POSITIVE REGULATION OF MOLECULAR FUNCTION 313 1791 4.425e-19 3.55e-17
59 RESPONSE TO OXYGEN CONTAINING COMPOUND 256 1381 6.148e-19 4.848e-17
60 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 271 1492 8.635e-19 6.696e-17
61 EPITHELIUM DEVELOPMENT 192 945 1.415e-18 1.078e-16
62 REGULATION OF CELL PROJECTION ORGANIZATION 132 558 1.436e-18 1.078e-16
63 TUBE DEVELOPMENT 131 552 1.464e-18 1.081e-16
64 POSITIVE REGULATION OF CELL PROLIFERATION 172 814 1.805e-18 1.312e-16
65 NEURON DEVELOPMENT 152 687 2.545e-18 1.822e-16
66 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 312 1805 2.689e-18 1.896e-16
67 NEURON PROJECTION MORPHOGENESIS 105 402 3.288e-18 2.283e-16
68 POSITIVE REGULATION OF CELL DEVELOPMENT 116 472 8.787e-18 6.012e-16
69 RESPONSE TO EXTERNAL STIMULUS 312 1821 1.001e-17 6.748e-16
70 NEURON PROJECTION DEVELOPMENT 127 545 2.385e-17 1.585e-15
71 EMBRYONIC MORPHOGENESIS 126 539 2.45e-17 1.606e-15
72 PHOSPHORYLATION 229 1228 2.71e-17 1.752e-15
73 EMBRYO DEVELOPMENT 180 894 4.726e-17 3.013e-15
74 IMMUNE SYSTEM PROCESS 331 1984 4.873e-17 3.064e-15
75 REGULATION OF SYSTEM PROCESS 120 507 5.292e-17 3.283e-15
76 RESPONSE TO WOUNDING 129 563 5.609e-17 3.434e-15
77 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 177 876 6.133e-17 3.706e-15
78 REGULATION OF CELL MORPHOGENESIS 127 552 7.002e-17 4.177e-15
79 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 200 1036 8.399e-17 4.885e-15
80 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 200 1036 8.399e-17 4.885e-15
81 EXTRACELLULAR STRUCTURE ORGANIZATION 84 304 2.248e-16 1.291e-14
82 ACTIN FILAMENT BASED PROCESS 109 450 2.645e-16 1.501e-14
83 CELL ACTIVATION 128 568 2.983e-16 1.672e-14
84 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 212 1135 3.922e-16 2.173e-14
85 RESPONSE TO NITROGEN COMPOUND 172 859 4.27e-16 2.338e-14
86 REGULATION OF VASCULATURE DEVELOPMENT 70 233 6.754e-16 3.654e-14
87 CELLULAR RESPONSE TO NITROGEN COMPOUND 117 505 7.037e-16 3.764e-14
88 RESPONSE TO GROWTH FACTOR 112 475 7.981e-16 4.22e-14
89 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 69 229 9.221e-16 4.715e-14
90 RESPONSE TO HORMONE 176 893 9.184e-16 4.715e-14
91 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 94 368 9.057e-16 4.715e-14
92 REGULATION OF TRANSPORT 302 1804 9.542e-16 4.826e-14
93 TAXIS 110 464 9.722e-16 4.864e-14
94 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 213 1152 1.029e-15 5.096e-14
95 TISSUE MORPHOGENESIS 121 533 1.118e-15 5.477e-14
96 CONNECTIVE TISSUE DEVELOPMENT 62 194 1.231e-15 5.966e-14
97 NEGATIVE REGULATION OF CELL PROLIFERATION 138 643 1.381e-15 6.623e-14
98 RESPONSE TO MECHANICAL STIMULUS 65 210 1.47e-15 6.979e-14
99 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 88 337 1.838e-15 8.641e-14
100 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 152 740 2.578e-15 1.2e-13
101 REGULATION OF ACTIN FILAMENT BASED PROCESS 83 312 3.713e-15 1.71e-13
102 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 322 1977 4.438e-15 2.024e-13
103 REGULATION OF EPITHELIAL CELL PROLIFERATION 78 285 4.719e-15 2.132e-13
104 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 120 541 8.837e-15 3.916e-13
105 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 120 541 8.837e-15 3.916e-13
106 REGULATION OF IMMUNE SYSTEM PROCESS 244 1403 1.129e-14 4.954e-13
107 NEGATIVE REGULATION OF CELL DEVELOPMENT 80 303 1.836e-14 7.985e-13
108 MUSCLE CELL DIFFERENTIATION 68 237 2.189e-14 9.431e-13
109 UROGENITAL SYSTEM DEVELOPMENT 79 299 2.568e-14 1.096e-12
110 IMMUNE SYSTEM DEVELOPMENT 125 582 2.986e-14 1.263e-12
111 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 176 926 3.053e-14 1.28e-12
112 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 102 437 3.192e-14 1.326e-12
113 POSITIVE REGULATION OF CATALYTIC ACTIVITY 257 1518 5.033e-14 2.072e-12
114 REGULATION OF MAPK CASCADE 136 660 6.263e-14 2.556e-12
115 NEGATIVE REGULATION OF GENE EXPRESSION 253 1493 7.334e-14 2.967e-12
116 POSITIVE REGULATION OF NEURON DIFFERENTIATION 79 306 9.866e-14 3.957e-12
117 CIRCULATORY SYSTEM PROCESS 89 366 1.181e-13 4.698e-12
118 SINGLE ORGANISM CELL ADHESION 104 459 1.359e-13 5.359e-12
119 REGULATION OF EPITHELIAL CELL MIGRATION 53 166 1.491e-13 5.832e-12
120 CELL CELL ADHESION 127 608 1.572e-13 6.095e-12
121 CELLULAR RESPONSE TO HORMONE STIMULUS 118 552 2.254e-13 8.668e-12
122 WOUND HEALING 105 470 2.688e-13 1.025e-11
123 LEUKOCYTE ACTIVATION 96 414 2.792e-13 1.056e-11
124 NEGATIVE REGULATION OF PHOSPHORYLATION 97 422 3.676e-13 1.379e-11
125 SENSORY ORGAN DEVELOPMENT 108 493 4.661e-13 1.735e-11
126 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 99 437 5.353e-13 1.961e-11
127 DEVELOPMENTAL GROWTH 82 333 5.347e-13 1.961e-11
128 REGULATION OF GTPASE ACTIVITY 135 673 6.359e-13 2.312e-11
129 REGULATION OF GROWTH 129 633 6.539e-13 2.359e-11
130 RESPONSE TO ABIOTIC STIMULUS 185 1024 8.231e-13 2.946e-11
131 REGULATION OF OSSIFICATION 54 178 8.972e-13 3.187e-11
132 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 108 498 9.197e-13 3.242e-11
133 GROWTH 94 410 1.001e-12 3.501e-11
134 POSITIVE REGULATION OF CELL DEATH 124 605 1.23e-12 4.271e-11
135 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 47 144 1.439e-12 4.961e-11
136 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 103 470 1.595e-12 5.457e-11
137 TUBE MORPHOGENESIS 79 323 2.069e-12 7.029e-11
138 CENTRAL NERVOUS SYSTEM DEVELOPMENT 162 872 2.406e-12 8.114e-11
139 CELL PROJECTION ORGANIZATION 166 902 2.838e-12 9.5e-11
140 REGULATION OF KINASE ACTIVITY 148 776 2.907e-12 9.601e-11
141 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 63 232 2.909e-12 9.601e-11
142 CELL FATE COMMITMENT 62 227 3.291e-12 1.079e-10
143 NEURON PROJECTION GUIDANCE 58 205 3.364e-12 1.094e-10
144 EPITHELIAL CELL DIFFERENTIATION 106 495 3.427e-12 1.107e-10
145 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 75 303 3.998e-12 1.283e-10
146 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 249 1517 4.061e-12 1.294e-10
147 LEUKOCYTE DIFFERENTIATION 73 292 4.627e-12 1.465e-10
148 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 58 207 5.222e-12 1.642e-10
149 RESPONSE TO ORGANIC CYCLIC COMPOUND 167 917 5.909e-12 1.845e-10
150 REGULATION OF BODY FLUID LEVELS 107 506 6.131e-12 1.902e-10
151 LYMPHOCYTE ACTIVATION 81 342 6.488e-12 1.999e-10
152 MUSCLE ORGAN DEVELOPMENT 70 277 7.419e-12 2.271e-10
153 REGULATION OF MAP KINASE ACTIVITY 77 319 7.942e-12 2.415e-10
154 MORPHOGENESIS OF AN EPITHELIUM 90 400 9.158e-12 2.767e-10
155 BEHAVIOR 108 516 9.485e-12 2.847e-10
156 POSITIVE REGULATION OF CELL ADHESION 86 376 1.064e-11 3.174e-10
157 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 69 274 1.243e-11 3.685e-10
158 MESENCHYME DEVELOPMENT 54 190 1.537e-11 4.525e-10
159 RESPONSE TO OXYGEN LEVELS 75 311 1.555e-11 4.55e-10
160 NEGATIVE REGULATION OF CELL DEATH 159 872 1.774e-11 5.16e-10
161 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 43 133 1.818e-11 5.253e-10
162 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 54 191 1.92e-11 5.514e-10
163 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 24 49 2.541e-11 7.254e-10
164 CARDIAC MUSCLE TISSUE DEVELOPMENT 44 140 3.081e-11 8.742e-10
165 STRIATED MUSCLE CELL DIFFERENTIATION 50 173 4.439e-11 1.252e-09
166 CARTILAGE DEVELOPMENT 45 147 4.982e-11 1.396e-09
167 REGULATION OF OSTEOBLAST DIFFERENTIATION 38 112 5.342e-11 1.488e-09
168 REGULATION OF HYDROLASE ACTIVITY 219 1327 5.603e-11 1.552e-09
169 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 35 98 5.964e-11 1.642e-09
170 REGULATION OF ANATOMICAL STRUCTURE SIZE 99 472 6.2e-11 1.697e-09
171 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 36 103 6.499e-11 1.768e-09
172 REGULATION OF HEMOPOIESIS 74 314 6.756e-11 1.828e-09
173 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 136 724 6.878e-11 1.85e-09
174 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 111 554 8.158e-11 2.181e-09
175 SINGLE ORGANISM BEHAVIOR 85 384 8.405e-11 2.235e-09
176 NEGATIVE REGULATION OF LOCOMOTION 65 263 1.153e-10 3.048e-09
177 BONE DEVELOPMENT 46 156 1.252e-10 3.291e-09
178 REGULATION OF BLOOD CIRCULATION 70 295 1.595e-10 4.17e-09
179 REGULATION OF DEVELOPMENTAL GROWTH 69 289 1.614e-10 4.195e-09
180 STEM CELL DIFFERENTIATION 52 190 1.668e-10 4.311e-09
181 REGULATION OF RESPONSE TO STRESS 235 1468 2.098e-10 5.383e-09
182 REGULATION OF CHEMOTAXIS 50 180 2.106e-10 5.383e-09
183 LEUKOCYTE CELL CELL ADHESION 63 255 2.257e-10 5.738e-09
184 POSITIVE REGULATION OF MAPK CASCADE 97 470 2.452e-10 6.2e-09
185 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 42 138 2.663e-10 6.697e-09
186 EMBRYONIC ORGAN DEVELOPMENT 87 406 2.918e-10 7.301e-09
187 SECRETION BY CELL 99 486 3.397e-10 8.452e-09
188 MESENCHYMAL CELL DIFFERENTIATION 41 134 3.614e-10 8.946e-09
189 ENDOTHELIUM DEVELOPMENT 32 90 4.465e-10 1.099e-08
190 HEART MORPHOGENESIS 55 212 4.505e-10 1.103e-08
191 POSITIVE REGULATION OF KINASE ACTIVITY 98 482 4.644e-10 1.131e-08
192 REGULATION OF CELL SUBSTRATE ADHESION 48 173 5.023e-10 1.217e-08
193 NEGATIVE REGULATION OF GROWTH 59 236 5.108e-10 1.231e-08
194 REGULATION OF CELL GROWTH 84 391 5.185e-10 1.244e-08
195 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 86 404 5.224e-10 1.247e-08
196 REGULATION OF CELLULAR COMPONENT BIOGENESIS 139 767 5.375e-10 1.276e-08
197 POSITIVE REGULATION OF HYDROLASE ACTIVITY 158 905 5.867e-10 1.386e-08
198 REGULATION OF RESPONSE TO WOUNDING 87 413 7.183e-10 1.688e-08
199 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 63 262 7.365e-10 1.722e-08
200 LYMPHOCYTE DIFFERENTIATION 54 209 7.605e-10 1.769e-08
201 REGULATION OF MEMBRANE POTENTIAL 76 343 7.968e-10 1.844e-08
202 REGULATION OF HEART CONTRACTION 56 221 8.157e-10 1.879e-08
203 REGULATION OF TRANSFERASE ACTIVITY 163 946 8.4e-10 1.925e-08
204 REGULATION OF CYTOPLASMIC TRANSPORT 97 481 8.986e-10 2.05e-08
205 REGULATION OF METAL ION TRANSPORT 73 325 9.093e-10 2.064e-08
206 DEVELOPMENTAL MATURATION 51 193 9.6e-10 2.168e-08
207 MUSCLE SYSTEM PROCESS 66 282 9.753e-10 2.192e-08
208 CELL PART MORPHOGENESIS 119 633 1.049e-09 2.346e-08
209 MUSCLE CELL DEVELOPMENT 39 128 1.105e-09 2.461e-08
210 RESPONSE TO PEPTIDE 85 404 1.199e-09 2.657e-08
211 LEUKOCYTE MIGRATION 62 259 1.213e-09 2.674e-08
212 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 65 278 1.361e-09 2.987e-08
213 POSITIVE REGULATION OF OSSIFICATION 30 84 1.374e-09 3.001e-08
214 REGULATION OF MUSCLE SYSTEM PROCESS 51 195 1.416e-09 3.08e-08
215 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 94 465 1.438e-09 3.112e-08
216 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 181 1087 1.491e-09 3.212e-08
217 SECRETION 112 588 1.509e-09 3.235e-08
218 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 116 616 1.542e-09 3.292e-08
219 REGULATION OF CELL CELL ADHESION 81 380 1.553e-09 3.3e-08
220 REGULATION OF CELLULAR LOCALIZATION 206 1277 1.609e-09 3.403e-08
221 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 50 190 1.629e-09 3.43e-08
222 CYTOSKELETON ORGANIZATION 147 838 1.72e-09 3.606e-08
223 HEAD DEVELOPMENT 129 709 1.775e-09 3.703e-08
224 CELLULAR RESPONSE TO PEPTIDE 64 274 1.899e-09 3.944e-08
225 RESPONSE TO PURINE CONTAINING COMPOUND 44 158 2.307e-09 4.77e-08
226 CELLULAR RESPONSE TO ACID CHEMICAL 47 175 2.437e-09 5.017e-08
227 REGULATION OF INTRACELLULAR TRANSPORT 116 621 2.514e-09 5.154e-08
228 CELL SUBSTRATE ADHESION 45 164 2.543e-09 5.191e-08
229 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 37 121 2.625e-09 5.333e-08
230 REGULATION OF CELL ACTIVATION 96 484 2.699e-09 5.46e-08
231 RESPONSE TO LIPID 153 888 2.851e-09 5.742e-08
232 CARDIOCYTE DIFFERENTIATION 32 96 2.873e-09 5.763e-08
233 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 26 68 3.18e-09 6.351e-08
234 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 43 154 3.198e-09 6.36e-08
235 SECOND MESSENGER MEDIATED SIGNALING 44 160 3.534e-09 6.998e-08
236 POSITIVE REGULATION OF TRANSPORT 159 936 3.839e-09 7.568e-08
237 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 24 60 4.415e-09 8.668e-08
238 REGULATION OF ENDOTHELIAL CELL MIGRATION 35 114 6.231e-09 1.214e-07
239 REGULATION OF HOMOTYPIC CELL CELL ADHESION 68 307 6.233e-09 1.214e-07
240 MEMBRANE DEPOLARIZATION DURING CARDIAC MUSCLE CELL ACTION POTENTIAL 11 14 6.262e-09 1.214e-07
241 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 75 352 6.354e-09 1.227e-07
242 REGULATION OF BINDING 64 283 7.38e-09 1.419e-07
243 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 35 115 8.033e-09 1.538e-07
244 FORMATION OF PRIMARY GERM LAYER 34 110 8.438e-09 1.606e-07
245 REGULATION OF HOMEOSTATIC PROCESS 89 447 8.458e-09 1.606e-07
246 NEGATIVE REGULATION OF CELL GROWTH 45 170 8.625e-09 1.631e-07
247 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 32 100 8.955e-09 1.687e-07
248 POSITIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 16 30 1.116e-08 2.094e-07
249 REGULATION OF CELLULAR COMPONENT SIZE 72 337 1.128e-08 2.108e-07
250 SKELETAL SYSTEM MORPHOGENESIS 50 201 1.248e-08 2.323e-07
251 ENDOTHELIAL CELL DIFFERENTIATION 26 72 1.301e-08 2.411e-07
252 EYE DEVELOPMENT 70 326 1.45e-08 2.677e-07
253 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 51 208 1.501e-08 2.76e-07
254 MULTICELLULAR ORGANISMAL SIGNALING 36 123 1.557e-08 2.841e-07
255 T CELL DIFFERENTIATION 36 123 1.557e-08 2.841e-07
256 CELL JUNCTION ORGANIZATION 47 185 1.667e-08 3.03e-07
257 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 147 867 1.728e-08 3.129e-07
258 INOSITOL LIPID MEDIATED SIGNALING 36 124 1.968e-08 3.549e-07
259 KIDNEY EPITHELIUM DEVELOPMENT 36 125 2.478e-08 4.452e-07
260 CELLULAR RESPONSE TO LIPID 89 457 2.52e-08 4.51e-07
261 HEMOSTASIS 67 311 2.566e-08 4.575e-07
262 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 31 99 2.698e-08 4.773e-07
263 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 31 99 2.698e-08 4.773e-07
264 AMEBOIDAL TYPE CELL MIGRATION 41 154 3.268e-08 5.759e-07
265 REGULATION OF ION TRANSPORT 108 592 3.295e-08 5.786e-07
266 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 76 372 3.355e-08 5.868e-07
267 OSSIFICATION 57 251 4.128e-08 7.193e-07
268 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 111 616 4.189e-08 7.273e-07
269 CELL DEATH 163 1001 4.834e-08 8.337e-07
270 REGULATION OF CALCIUM ION TRANSPORT 50 209 4.838e-08 8.337e-07
271 REGULATION OF HEART RATE 28 86 4.918e-08 8.444e-07
272 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 24 67 5.6e-08 9.579e-07
273 EPITHELIAL CELL DEVELOPMENT 46 186 5.687e-08 9.693e-07
274 NEGATIVE REGULATION OF TRANSPORT 88 458 5.74e-08 9.748e-07
275 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 31 102 5.852e-08 9.902e-07
276 NEGATIVE REGULATION OF CELL ADHESION 52 223 6.453e-08 1.088e-06
277 REGULATION OF STEM CELL DIFFERENTIATION 33 113 6.475e-08 1.088e-06
278 LUNG ALVEOLUS DEVELOPMENT 18 41 6.796e-08 1.137e-06
279 CELL CELL SIGNALING 131 767 6.874e-08 1.146e-06
280 CARDIAC MUSCLE CELL ACTION POTENTIAL 17 37 6.896e-08 1.146e-06
281 CELL MATRIX ADHESION 34 119 7.445e-08 1.233e-06
282 REGULATED EXOCYTOSIS 52 224 7.532e-08 1.243e-06
283 REGULATION OF CELL JUNCTION ASSEMBLY 24 68 7.77e-08 1.273e-06
284 ORGAN GROWTH 24 68 7.77e-08 1.273e-06
285 ACTIN FILAMENT BASED MOVEMENT 29 93 8.319e-08 1.353e-06
286 MULTICELLULAR ORGANISM METABOLIC PROCESS 29 93 8.319e-08 1.353e-06
287 SKELETAL MUSCLE ORGAN DEVELOPMENT 37 137 1.009e-07 1.636e-06
288 RESPONSE TO ALCOHOL 73 362 1.076e-07 1.739e-06
289 CARDIAC MUSCLE CELL DIFFERENTIATION 25 74 1.124e-07 1.809e-06
290 GASTRULATION 40 155 1.202e-07 1.929e-06
291 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 38 144 1.319e-07 2.109e-06
292 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 29 95 1.394e-07 2.222e-06
293 EMBRYONIC ORGAN MORPHOGENESIS 60 279 1.444e-07 2.293e-06
294 NEGATIVE REGULATION OF RESPONSE TO WOUNDING 40 156 1.45e-07 2.295e-06
295 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 41 162 1.497e-07 2.362e-06
296 RESPONSE TO ORGANOPHOSPHORUS 37 139 1.511e-07 2.376e-06
297 REGULATION OF AXONOGENESIS 42 168 1.533e-07 2.401e-06
298 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 33 117 1.611e-07 2.515e-06
299 HOMEOSTATIC PROCESS 204 1337 1.643e-07 2.557e-06
300 RESPONSE TO STEROID HORMONE 92 497 1.737e-07 2.693e-06
301 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 118 684 1.807e-07 2.794e-06
302 APPENDAGE DEVELOPMENT 42 169 1.829e-07 2.808e-06
303 LIMB DEVELOPMENT 42 169 1.829e-07 2.808e-06
304 CELL JUNCTION ASSEMBLY 35 129 1.959e-07 2.998e-06
305 MODULATION OF SYNAPTIC TRANSMISSION 63 301 1.996e-07 3.046e-06
306 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 62 296 2.42e-07 3.679e-06
307 MUCOPOLYSACCHARIDE METABOLIC PROCESS 31 108 2.463e-07 3.734e-06
308 REGULATION OF LEUKOCYTE DIFFERENTIATION 52 232 2.477e-07 3.742e-06
309 CHEMICAL HOMEOSTASIS 143 874 2.488e-07 3.745e-06
310 REGULATION OF ION HOMEOSTASIS 47 201 2.495e-07 3.745e-06
311 REGULATION OF MYELOID CELL DIFFERENTIATION 44 183 2.595e-07 3.882e-06
312 CARDIAC CONDUCTION 26 82 2.653e-07 3.956e-06
313 ACTOMYOSIN STRUCTURE ORGANIZATION 25 77 2.691e-07 4.001e-06
314 FOREBRAIN DEVELOPMENT 71 357 2.797e-07 4.144e-06
315 DIGESTIVE SYSTEM DEVELOPMENT 38 148 2.836e-07 4.19e-06
316 AMINOGLYCAN METABOLIC PROCESS 41 166 3.047e-07 4.486e-06
317 CYTOKINE PRODUCTION 33 120 3.081e-07 4.509e-06
318 REGULATION OF DENDRITE DEVELOPMENT 33 120 3.081e-07 4.509e-06
319 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 34 126 3.353e-07 4.89e-06
320 PLASMA MEMBRANE ORGANIZATION 47 203 3.401e-07 4.945e-06
321 PROTEOGLYCAN METABOLIC PROCESS 26 83 3.468e-07 5.027e-06
322 LIPID PHOSPHORYLATION 29 99 3.713e-07 5.365e-06
323 REGULATION OF CYTOKINE PRODUCTION 100 563 3.954e-07 5.695e-06
324 REGULATION OF TRANSPORTER ACTIVITY 46 198 4.066e-07 5.839e-06
325 PEPTIDYL TYROSINE MODIFICATION 44 186 4.224e-07 6.048e-06
326 MULTICELLULAR ORGANISMAL MACROMOLECULE METABOLIC PROCESS 25 79 4.671e-07 6.647e-06
327 BONE MORPHOGENESIS 25 79 4.671e-07 6.647e-06
328 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 60 289 5.156e-07 7.315e-06
329 REGULATION OF CHONDROCYTE DIFFERENTIATION 18 46 5.565e-07 7.87e-06
330 CELLULAR RESPONSE TO INSULIN STIMULUS 37 146 5.74e-07 8.093e-06
331 HEART PROCESS 26 85 5.831e-07 8.197e-06
332 COGNITION 54 251 5.883e-07 8.221e-06
333 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 21 60 5.868e-07 8.221e-06
334 NEGATIVE REGULATION OF CELL ACTIVATION 39 158 5.966e-07 8.312e-06
335 REGULATION OF TRANSMEMBRANE TRANSPORT 80 426 6.013e-07 8.351e-06
336 NEGATIVE REGULATION OF VASCULATURE DEVELOPMENT 25 80 6.1e-07 8.448e-06
337 ARTERY DEVELOPMENT 24 75 6.269e-07 8.63e-06
338 NEURAL CREST CELL DIFFERENTIATION 24 75 6.269e-07 8.63e-06
339 SENSORY ORGAN MORPHOGENESIS 52 239 6.577e-07 9.027e-06
340 EAR DEVELOPMENT 45 195 6.608e-07 9.043e-06
341 PLATELET DEGRANULATION 30 107 6.669e-07 9.1e-06
342 MYELOID CELL DIFFERENTIATION 44 189 6.775e-07 9.218e-06
343 MUSCLE CONTRACTION 51 233 6.93e-07 9.401e-06
344 CELL PROLIFERATION 114 672 6.96e-07 9.415e-06
345 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 38 153 7.013e-07 9.459e-06
346 PLATELET DERIVED GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 15 34 7.853e-07 1.053e-05
347 CAMP METABOLIC PROCESS 15 34 7.853e-07 1.053e-05
348 REPRODUCTIVE SYSTEM DEVELOPMENT 77 408 7.964e-07 1.065e-05
349 MEMBRANE DEPOLARIZATION 21 61 8.04e-07 1.072e-05
350 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 43 184 8.091e-07 1.076e-05
351 REGULATION OF CELL SIZE 41 172 8.346e-07 1.106e-05
352 TELENCEPHALON DEVELOPMENT 50 228 8.364e-07 1.106e-05
353 CELL MATURATION 34 131 8.995e-07 1.186e-05
354 NEGATIVE REGULATION OF MOLECULAR FUNCTION 167 1079 9.571e-07 1.258e-05
355 CHONDROITIN SULFATE PROTEOGLYCAN METABOLIC PROCESS 17 43 9.655e-07 1.265e-05
356 POSITIVE REGULATION OF CHEMOTAXIS 32 120 9.785e-07 1.279e-05
357 REGULATION OF ORGAN MORPHOGENESIS 52 242 9.822e-07 1.28e-05
358 REGULATION OF CYTOSKELETON ORGANIZATION 90 502 9.945e-07 1.293e-05
359 REGULATION OF WOUND HEALING 33 126 1.038e-06 1.346e-05
360 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 21 62 1.092e-06 1.412e-05
361 NEPHRON DEVELOPMENT 31 115 1.116e-06 1.438e-05
362 CARDIAC CHAMBER DEVELOPMENT 36 144 1.152e-06 1.477e-05
363 RESPONSE TO CAMP 29 104 1.152e-06 1.477e-05
364 RESPONSE TO INSULIN 46 205 1.156e-06 1.477e-05
365 REGULATION OF CATABOLIC PROCESS 121 731 1.165e-06 1.485e-05
366 CELL CHEMOTAXIS 39 162 1.175e-06 1.494e-05
367 NEGATIVE REGULATION OF KINASE ACTIVITY 53 250 1.199e-06 1.52e-05
368 EXOCYTOSIS 62 310 1.28e-06 1.618e-05
369 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 28 99 1.284e-06 1.619e-05
370 CELLULAR RESPONSE TO EXTERNAL STIMULUS 55 264 1.352e-06 1.7e-05
371 SYNAPSE ORGANIZATION 36 145 1.375e-06 1.724e-05
372 ACTION POTENTIAL 27 94 1.419e-06 1.774e-05
373 IN UTERO EMBRYONIC DEVELOPMENT 62 311 1.432e-06 1.787e-05
374 REGULATION OF CARTILAGE DEVELOPMENT 21 63 1.472e-06 1.822e-05
375 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 47 213 1.468e-06 1.822e-05
376 REGULATION OF MUSCLE ADAPTATION 21 63 1.472e-06 1.822e-05
377 POSITIVE REGULATION OF MAP KINASE ACTIVITY 46 207 1.538e-06 1.898e-05
378 RESPONSE TO INORGANIC SUBSTANCE 86 479 1.62e-06 1.995e-05
379 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 37 152 1.647e-06 2.022e-05
380 SYSTEM PROCESS 254 1785 1.764e-06 2.161e-05
381 RESPONSE TO DRUG 79 431 1.885e-06 2.297e-05
382 NEGATIVE REGULATION OF NEURON DEATH 40 171 1.882e-06 2.297e-05
383 REGULATION OF EXTENT OF CELL GROWTH 28 101 1.987e-06 2.414e-05
384 RESPIRATORY SYSTEM DEVELOPMENT 44 197 2.231e-06 2.703e-05
385 CELL SUBSTRATE JUNCTION ASSEMBLY 16 41 2.467e-06 2.982e-05
386 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 22 70 2.556e-06 3.081e-05
387 CHONDROCYTE DIFFERENTIATION 20 60 2.605e-06 3.132e-05
388 MORPHOGENESIS OF A BRANCHING STRUCTURE 39 167 2.627e-06 3.151e-05
389 PROTEIN AUTOPHOSPHORYLATION 43 192 2.685e-06 3.212e-05
390 RAS PROTEIN SIGNAL TRANSDUCTION 35 143 2.722e-06 3.248e-05
391 CELL COMMUNICATION INVOLVED IN CARDIAC CONDUCTION 15 37 2.888e-06 3.437e-05
392 POSITIVE REGULATION OF PROTEIN KINASE B SIGNALING 24 81 2.942e-06 3.492e-05
393 PROTEIN LOCALIZATION 255 1805 2.954e-06 3.497e-05
394 REGULATION OF PROTEIN BINDING 39 168 3.069e-06 3.624e-05
395 RHYTHMIC PROCESS 59 298 3.204e-06 3.774e-05
396 ARTERY MORPHOGENESIS 18 51 3.237e-06 3.803e-05
397 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 49 232 3.333e-06 3.907e-05
398 MEMBRANE ASSEMBLY 12 25 3.393e-06 3.957e-05
399 CHONDROITIN SULFATE BIOSYNTHETIC PROCESS 12 25 3.393e-06 3.957e-05
400 NEGATIVE REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 21 66 3.445e-06 3.978e-05
401 RESPONSE TO ACID CHEMICAL 62 319 3.433e-06 3.978e-05
402 NEGATIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 21 66 3.445e-06 3.978e-05
403 REGULATION OF CARDIAC MUSCLE CONTRACTION 21 66 3.445e-06 3.978e-05
404 CARDIAC MUSCLE CELL CONTRACTION 13 29 3.457e-06 3.982e-05
405 GLIOGENESIS 40 175 3.474e-06 3.991e-05
406 REGULATION OF NEURON DEATH 52 252 3.482e-06 3.991e-05
407 CARDIAC CHAMBER MORPHOGENESIS 28 104 3.724e-06 4.258e-05
408 NEGATIVE REGULATION OF MAPK CASCADE 35 145 3.816e-06 4.352e-05
409 NEURON MIGRATION 29 110 3.975e-06 4.522e-05
410 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 30 116 4.176e-06 4.74e-05
411 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 31 122 4.329e-06 4.889e-05
412 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 31 122 4.329e-06 4.889e-05
413 REGULATION OF PROTEIN LOCALIZATION 147 950 4.416e-06 4.975e-05
414 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 21 67 4.509e-06 5.068e-05
415 CARDIAC VENTRICLE MORPHOGENESIS 20 62 4.622e-06 5.183e-05
416 RESPONSE TO FLUID SHEAR STRESS 14 34 4.974e-06 5.563e-05
417 REGULATION OF JNK CASCADE 37 159 5.122e-06 5.716e-05
418 CELL FATE DETERMINATION 16 43 5.139e-06 5.72e-05
419 CELL CELL SIGNALING INVOLVED IN CARDIAC CONDUCTION 11 22 5.301e-06 5.887e-05
420 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 43 197 5.412e-06 5.996e-05
421 REGULATION OF FAT CELL DIFFERENTIATION 28 106 5.562e-06 6.133e-05
422 FAT CELL DIFFERENTIATION 28 106 5.562e-06 6.133e-05
423 MYOFIBRIL ASSEMBLY 17 48 5.728e-06 6.301e-05
424 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 24 84 5.936e-06 6.514e-05
425 PROTEOGLYCAN BIOSYNTHETIC PROCESS 19 58 6.169e-06 6.753e-05
426 MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL 15 39 6.283e-06 6.847e-05
427 NEGATIVE CHEMOTAXIS 15 39 6.283e-06 6.847e-05
428 GLAND DEVELOPMENT 72 395 6.488e-06 7.053e-05
429 AMINOGLYCAN BIOSYNTHETIC PROCESS 28 107 6.764e-06 7.336e-05
430 IMMUNE RESPONSE 165 1100 7.311e-06 7.911e-05
431 LEARNING 32 131 7.482e-06 8.078e-05
432 GLOMERULUS DEVELOPMENT 17 49 7.891e-06 8.499e-05
433 POSITIVE REGULATION OF CHONDROCYTE DIFFERENTIATION 10 19 7.979e-06 8.574e-05
434 REGULATION OF SECRETION 113 699 8.052e-06 8.632e-05
435 MULTI MULTICELLULAR ORGANISM PROCESS 45 213 8.163e-06 8.731e-05
436 CELLULAR RESPONSE TO MECHANICAL STIMULUS 23 80 8.225e-06 8.777e-05
437 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 36 156 8.342e-06 8.883e-05
438 ENDODERMAL CELL DIFFERENTIATION 15 40 9.05e-06 9.614e-05
439 REGULATION OF MUSCLE TISSUE DEVELOPMENT 27 103 9.474e-06 0.0001004
440 PROTEIN LOCALIZATION TO CELL PERIPHERY 35 151 9.988e-06 0.0001056
441 ENDOCHONDRAL BONE MORPHOGENESIS 16 45 1.015e-05 0.0001071
442 REGULATION OF PROTEIN KINASE B SIGNALING 30 121 1.04e-05 0.0001095
443 CELLULAR RESPONSE TO CAMP 17 50 1.076e-05 0.0001126
444 REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 19 60 1.076e-05 0.0001126
445 ENDODERM FORMATION 17 50 1.076e-05 0.0001126
446 REGULATION OF POSTSYNAPTIC MEMBRANE POTENTIAL 18 55 1.093e-05 0.0001139
447 REGULATION OF PROTEIN IMPORT 40 183 1.094e-05 0.0001139
448 POSITIVE REGULATION OF AXON EXTENSION 14 36 1.1e-05 0.0001143
449 RETINA VASCULATURE DEVELOPMENT IN CAMERA TYPE EYE 9 16 1.133e-05 0.0001174
450 REGULATION OF CALCIUM MEDIATED SIGNALING 22 76 1.139e-05 0.0001177
451 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 27 104 1.149e-05 0.0001185
452 POSITIVE REGULATION OF CATABOLIC PROCESS 71 395 1.227e-05 0.0001264
453 INTEGRIN MEDIATED SIGNALING PATHWAY 23 82 1.289e-05 0.0001324
454 NEGATIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 13 32 1.294e-05 0.0001327
455 PALLIUM DEVELOPMENT 35 153 1.355e-05 0.0001382
456 RESPONSE TO REACTIVE OXYGEN SPECIES 41 191 1.355e-05 0.0001382
457 REGULATION OF MUSCLE CONTRACTION 34 147 1.395e-05 0.000142
458 PATTERN SPECIFICATION PROCESS 74 418 1.4e-05 0.0001423
459 ESTABLISHMENT OF CELL POLARITY 24 88 1.418e-05 0.0001438
460 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 28 111 1.432e-05 0.0001446
461 REGULATION OF BMP SIGNALING PATHWAY 22 77 1.433e-05 0.0001446
462 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 32 135 1.453e-05 0.0001457
463 ADULT BEHAVIOR 32 135 1.453e-05 0.0001457
464 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 37 166 1.453e-05 0.0001457
465 RESPONSE TO BMP 25 94 1.526e-05 0.0001524
466 CELLULAR RESPONSE TO BMP STIMULUS 25 94 1.526e-05 0.0001524
467 REGULATION OF NEURON APOPTOTIC PROCESS 41 192 1.545e-05 0.000154
468 REGULATION OF MUSCLE HYPERTROPHY 14 37 1.594e-05 0.0001585
469 REGENERATION 36 161 1.751e-05 0.0001737
470 REGULATION OF INFLAMMATORY RESPONSE 56 294 1.842e-05 0.0001823
471 ION HOMEOSTASIS 95 576 1.879e-05 0.0001856
472 CYCLIC NUCLEOTIDE METABOLIC PROCESS 18 57 1.905e-05 0.0001878
473 NEURON RECOGNITION 13 33 1.924e-05 0.0001893
474 VESICLE MEDIATED TRANSPORT 180 1239 1.937e-05 0.0001898
475 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 45 220 1.938e-05 0.0001898
476 NEGATIVE REGULATION OF MAP KINASE ACTIVITY 21 73 1.988e-05 0.0001939
477 LOCOMOTORY BEHAVIOR 39 181 1.985e-05 0.0001939
478 RESPONSE TO CYTOKINE 113 714 2.112e-05 0.0002056
479 CALCIUM MEDIATED SIGNALING 24 90 2.138e-05 0.0002068
480 REGULATION OF CELL MATRIX ADHESION 24 90 2.138e-05 0.0002068
481 MESONEPHROS DEVELOPMENT 24 90 2.138e-05 0.0002068
482 NEGATIVE REGULATION OF PLATELET ACTIVATION 9 17 2.175e-05 0.00021
483 RESPONSE TO OXIDATIVE STRESS 64 352 2.244e-05 0.0002161
484 COLLAGEN FIBRIL ORGANIZATION 14 38 2.273e-05 0.0002186
485 MAINTENANCE OF CELL NUMBER 31 132 2.386e-05 0.0002289
486 OSTEOBLAST DIFFERENTIATION 30 126 2.423e-05 0.000232
487 PALATE DEVELOPMENT 23 85 2.441e-05 0.0002333
488 CHONDROCYTE DEVELOPMENT 10 21 2.483e-05 0.0002368
489 ACTIN MEDIATED CELL CONTRACTION 21 74 2.494e-05 0.0002374
490 REGULATION OF PROTEIN SECRETION 69 389 2.526e-05 0.0002398
491 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 17 53 2.57e-05 0.0002436
492 POSITIVE REGULATION OF ION TRANSPORT 47 236 2.633e-05 0.000249
493 ADHERENS JUNCTION ASSEMBLY 13 34 2.808e-05 0.0002645
494 HEART VALVE DEVELOPMENT 13 34 2.808e-05 0.0002645
495 REGULATION OF CELLULAR PROTEIN LOCALIZATION 91 552 2.846e-05 0.0002675
496 CELLULAR RESPONSE TO OXIDATIVE STRESS 39 184 2.942e-05 0.0002759
497 INSULIN LIKE GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 8 14 3.074e-05 0.0002877
498 REGULATION OF DEFENSE RESPONSE 118 759 3.142e-05 0.0002936
499 REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 24 92 3.171e-05 0.0002956
500 REGULATION OF AXON GUIDANCE 14 39 3.195e-05 0.0002973
501 VASCULOGENESIS 18 59 3.217e-05 0.0002988
502 ACTIVATION OF PROTEIN KINASE ACTIVITY 53 279 3.286e-05 0.0003046
503 MEMBRANE BIOGENESIS 12 30 3.361e-05 0.0003085
504 CHONDROITIN SULFATE PROTEOGLYCAN BIOSYNTHETIC PROCESS 12 30 3.361e-05 0.0003085
505 NEGATIVE REGULATION OF HEMOPOIESIS 30 128 3.34e-05 0.0003085
506 REGULATION OF HEART RATE BY CARDIAC CONDUCTION 12 30 3.361e-05 0.0003085
507 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 44 218 3.35e-05 0.0003085
508 TISSUE REMODELING 23 87 3.658e-05 0.0003351
509 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 65 365 3.777e-05 0.0003453
510 NEPHRON EPITHELIUM DEVELOPMENT 24 93 3.84e-05 0.0003503
511 INOSITOL PHOSPHATE MEDIATED SIGNALING 9 18 3.932e-05 0.000358
512 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 97 602 3.954e-05 0.0003594
513 CEREBRAL CORTEX DEVELOPMENT 26 105 4.035e-05 0.000366
514 PEPTIDYL SERINE MODIFICATION 33 148 4.086e-05 0.0003699
515 POSITIVE REGULATION OF MUSCLE HYPERTROPHY 10 22 4.111e-05 0.0003707
516 POSITIVE REGULATION OF CARDIAC MUSCLE HYPERTROPHY 10 22 4.111e-05 0.0003707
517 PLATELET ACTIVATION 32 142 4.26e-05 0.0003834
518 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 67 381 4.337e-05 0.0003885
519 ENDODERM DEVELOPMENT 20 71 4.341e-05 0.0003885
520 ADHERENS JUNCTION ORGANIZATION 20 71 4.341e-05 0.0003885
521 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 14 40 4.427e-05 0.0003947
522 GLIAL CELL DIFFERENTIATION 31 136 4.42e-05 0.0003947
523 REGULATION OF STEM CELL PROLIFERATION 23 88 4.451e-05 0.000396
524 REGULATION OF ADHERENS JUNCTION ORGANIZATION 16 50 4.564e-05 0.0004045
525 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 16 50 4.564e-05 0.0004045
526 SPROUTING ANGIOGENESIS 15 45 4.591e-05 0.0004061
527 POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 25 100 4.748e-05 0.0004192
528 CARDIAC VENTRICLE DEVELOPMENT 26 106 4.802e-05 0.0004232
529 REGULATION OF VASOCONSTRICTION 19 66 4.818e-05 0.0004238
530 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 45 228 4.858e-05 0.0004265
531 POSITIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 35 162 4.872e-05 0.0004269
532 NEGATIVE REGULATION OF INTRACELLULAR TRANSPORT 32 143 4.927e-05 0.0004309
533 REGULATION OF PLATELET ACTIVATION 12 31 4.945e-05 0.0004317
534 REGULATION OF ACTIN FILAMENT LENGTH 34 156 5.148e-05 0.0004486
535 RESPONSE TO KETONE 38 182 5.223e-05 0.0004543
536 REGULATION OF BLOOD PRESSURE 36 169 5.24e-05 0.0004549
537 POSITIVE REGULATION OF TRANSMEMBRANE TRANSPORT 30 131 5.31e-05 0.0004593
538 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 30 131 5.31e-05 0.0004593
539 POST EMBRYONIC DEVELOPMENT 23 89 5.394e-05 0.0004656
540 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 42 209 5.551e-05 0.0004783
541 POSITIVE REGULATION OF CELL CELL ADHESION 47 243 5.65e-05 0.0004859
542 POSITIVE REGULATION OF PROTEIN ACETYLATION 13 36 5.68e-05 0.0004868
543 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 17 56 5.681e-05 0.0004868
544 REGULATION OF CARDIAC MUSCLE CELL CONTRACTION 11 27 5.857e-05 0.0005009
545 AMINO ACID IMPORT 8 15 5.959e-05 0.0005088
546 NEGATIVE REGULATION OF CHEMOTAXIS 16 51 5.987e-05 0.0005102
547 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 14 41 6.057e-05 0.0005152
548 CYCLIC NUCLEOTIDE MEDIATED SIGNALING 15 46 6.135e-05 0.0005209
549 REGULATION OF LYMPHOCYTE DIFFERENTIATION 30 132 6.171e-05 0.000523
550 REGULATION OF NEUROTRANSMITTER LEVELS 39 190 6.217e-05 0.000526
551 REGULATION OF CARDIAC MUSCLE CONTRACTION BY CALCIUM ION SIGNALING 10 23 6.568e-05 0.0005546
552 MYELOID LEUKOCYTE DIFFERENTIATION 24 96 6.673e-05 0.0005615
553 REGULATION OF EMBRYONIC DEVELOPMENT 27 114 6.672e-05 0.0005615
554 DIVALENT INORGANIC CATION HOMEOSTASIS 61 343 6.712e-05 0.0005637
555 REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 26 108 6.742e-05 0.0005652
556 REGULATION OF ACTIN FILAMENT BASED MOVEMENT 12 32 7.136e-05 0.0005972
557 RESPONSE TO ESTROGEN 43 218 7.172e-05 0.0005991
558 REGULATION OF STRIATED MUSCLE CONTRACTION 21 79 7.205e-05 0.0006008
559 REGULATION OF CARBOHYDRATE METABOLIC PROCESS 36 172 7.697e-05 0.0006407
560 RESPONSE TO CALCIUM ION 27 115 7.831e-05 0.0006507
561 REGULATION OF SYNAPTIC PLASTICITY 31 140 7.913e-05 0.0006551
562 ADAPTIVE IMMUNE RESPONSE 53 288 7.901e-05 0.0006551
563 REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 26 109 7.954e-05 0.0006574
564 GLAND MORPHOGENESIS 24 97 7.968e-05 0.0006574
565 REGULATION OF MUSCLE ORGAN DEVELOPMENT 25 103 8.004e-05 0.0006592
566 REGULATION OF DENDRITE MORPHOGENESIS 20 74 8.25e-05 0.0006783
567 CARTILAGE MORPHOGENESIS 7 12 8.367e-05 0.0006866
568 REGULATION OF LIPID METABOLIC PROCESS 52 282 8.704e-05 0.000713
569 NEGATIVE REGULATION OF WOUND HEALING 17 58 9.276e-05 0.0007585
570 POSITIVE REGULATION OF AXONOGENESIS 19 69 9.374e-05 0.0007652
571 CELL GROWTH 30 135 9.556e-05 0.0007787
572 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 16 53 0.0001004 0.0008125
573 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 69 406 1e-04 0.0008125
574 CELLULAR RESPONSE TO AMINO ACID STIMULUS 16 53 0.0001004 0.0008125
575 POSITIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 16 53 0.0001004 0.0008125
576 FOCAL ADHESION ASSEMBLY 10 24 0.0001017 0.0008158
577 REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 20 75 0.0001012 0.0008158
578 POSITIVE REGULATION OF CELL JUNCTION ASSEMBLY 10 24 0.0001017 0.0008158
579 CELL SUBSTRATE ADHERENS JUNCTION ASSEMBLY 10 24 0.0001017 0.0008158
580 CARDIAC EPITHELIAL TO MESENCHYMAL TRANSITION 10 24 0.0001017 0.0008158
581 REGULATION OF PEPTIDE TRANSPORT 48 256 0.0001052 0.0008426
582 REGULATION OF LIPID KINASE ACTIVITY 15 48 0.0001063 0.0008485
583 POSITIVE REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 15 48 0.0001063 0.0008485
584 METANEPHROS DEVELOPMENT 21 81 0.0001066 0.0008495
585 NEGATIVE REGULATION OF CYTOPLASMIC TRANSPORT 27 117 0.0001071 0.0008516
586 NEGATIVE REGULATION OF ADHERENS JUNCTION ORGANIZATION 8 16 0.0001079 0.000855
587 REGULATION OF MACROPHAGE CHEMOTAXIS 8 16 0.0001079 0.000855
588 POSITIVE REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 13 38 0.0001081 0.0008558
589 REGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS 22 87 0.0001102 0.0008705
590 NEGATIVE REGULATION OF CELL JUNCTION ASSEMBLY 9 20 0.000111 0.0008708
591 REGULATION OF MACROPHAGE DIFFERENTIATION 9 20 0.000111 0.0008708
592 LYMPH VESSEL DEVELOPMENT 9 20 0.000111 0.0008708
593 MELANOCYTE DIFFERENTIATION 9 20 0.000111 0.0008708
594 POSITIVE REGULATION OF CYTOSKELETON ORGANIZATION 36 175 0.0001115 0.0008737
595 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 124 829 0.0001134 0.0008868
596 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 19 70 0.0001157 0.0009036
597 LIPID LOCALIZATION 49 264 0.0001162 0.0009056
598 REGULATION OF PROTEIN TARGETING 55 307 0.0001226 0.0009537
599 MULTICELLULAR ORGANISM GROWTH 20 76 0.0001235 0.0009577
600 EXTRACELLULAR MATRIX DISASSEMBLY 20 76 0.0001235 0.0009577
601 REGULATION OF VACUOLAR TRANSPORT 11 29 0.0001266 0.0009784
602 POSITIVE REGULATION OF CARTILAGE DEVELOPMENT 11 29 0.0001266 0.0009784
603 REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 18 65 0.0001313 0.001013
604 REGULATION OF COAGULATION 22 88 0.0001321 0.001016
605 REGULATION OF CATION CHANNEL ACTIVITY 22 88 0.0001321 0.001016
606 PROTEIN DEPHOSPHORYLATION 38 190 0.0001359 0.001044
607 CELLULAR HOMEOSTASIS 104 676 0.0001374 0.001053
608 CARDIAC CELL DEVELOPMENT 15 49 0.000138 0.001056
609 POSITIVE REGULATION OF GROWTH 45 238 0.0001394 0.001065
610 NEGATIVE REGULATION OF CELL CELL ADHESION 30 138 0.0001452 0.001108
611 TRABECULA MORPHOGENESIS 13 39 0.0001462 0.001112
612 POSITIVE REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 13 39 0.0001462 0.001112
613 NEGATIVE REGULATION OF CYTOKINE PRODUCTION 41 211 0.0001468 0.001114
614 STEM CELL PROLIFERATION 17 60 0.0001473 0.001116
615 IMMUNE EFFECTOR PROCESS 79 486 0.0001493 0.00113
616 DEVELOPMENTAL CELL GROWTH 20 77 0.0001501 0.001133
617 CELLULAR EXTRAVASATION 10 25 0.0001531 0.001151
618 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL BY SARCOPLASMIC RETICULUM 10 25 0.0001531 0.001151
619 PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 10 25 0.0001531 0.001151
620 CELLULAR CHEMICAL HOMEOSTASIS 90 570 0.000154 0.001155
621 GLYCOPROTEIN METABOLIC PROCESS 61 353 0.0001542 0.001155
622 ORGAN REGENERATION 21 83 0.0001551 0.001161
623 SOMATIC STEM CELL POPULATION MAINTENANCE 18 66 0.0001624 0.001209
624 MESODERM MORPHOGENESIS 18 66 0.0001624 0.001209
625 REGULATION OF CARDIAC CONDUCTION 18 66 0.0001624 0.001209
626 PERIPHERAL NERVOUS SYSTEM NEURON DIFFERENTIATION 7 13 0.0001643 0.001219
627 PERIPHERAL NERVOUS SYSTEM NEURON DEVELOPMENT 7 13 0.0001643 0.001219
628 REGIONALIZATION 55 311 0.0001733 0.001284
629 POSITIVE REGULATION OF ENDOCYTOSIS 26 114 0.0001745 0.001291
630 LIPID TRANSLOCATION 9 21 0.0001756 0.001297
631 RESPONSE TO ESTRADIOL 31 146 0.0001787 0.001317
632 NEGATIVE REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 11 30 0.0001804 0.001324
633 REGULATION OF MEMBRANE REPOLARIZATION 11 30 0.0001804 0.001324
634 LAMELLIPODIUM ASSEMBLY 11 30 0.0001804 0.001324
635 RENAL TUBULE DEVELOPMENT 20 78 0.0001815 0.00133
636 CYCLIC NUCLEOTIDE CATABOLIC PROCESS 8 17 0.0001844 0.001341
637 REGULATION OF PHOSPHOLIPID METABOLIC PROCESS 17 61 0.0001838 0.001341
638 NEGATIVE REGULATION OF ANOIKIS 8 17 0.0001844 0.001341
639 REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 8 17 0.0001844 0.001341
640 NEGATIVE REGULATION OF HOMOTYPIC CELL CELL ADHESION 24 102 0.0001843 0.001341
641 POSITIVE REGULATION OF BINDING 28 127 0.0001853 0.001345
642 TISSUE MIGRATION 21 84 0.000186 0.001346
643 NEGATIVE REGULATION OF MYELOID CELL DIFFERENTIATION 21 84 0.000186 0.001346
644 ENDOTHELIAL CELL DEVELOPMENT 14 45 0.0001891 0.001366
645 RESPONSE TO MONOAMINE 12 35 0.0001935 0.001396
646 DEVELOPMENTAL PIGMENTATION 13 40 0.0001953 0.001407
647 NEURON FATE COMMITMENT 18 67 0.0001999 0.001437
648 EPITHELIAL TO MESENCHYMAL TRANSITION 16 56 0.0002057 0.001472
649 REGULATION OF DENDRITIC SPINE DEVELOPMENT 16 56 0.0002057 0.001472
650 CELLULAR RESPONSE TO ABIOTIC STIMULUS 48 263 0.0002051 0.001472
651 CELL CYCLE ARREST 32 154 0.0002154 0.001539
652 REGULATION OF CALCIUM ION IMPORT 24 103 0.000216 0.001541
653 ESTABLISHMENT OR MAINTENANCE OF CELL POLARITY 30 141 0.0002169 0.001546
654 REGULATION OF IMMUNE RESPONSE 126 858 0.0002201 0.001566
655 ENSHEATHMENT OF NEURONS 22 91 0.0002226 0.001579
656 AXON ENSHEATHMENT 22 91 0.0002226 0.001579
657 REPLACEMENT OSSIFICATION 10 26 0.0002247 0.00158
658 AGING 48 264 0.0002248 0.00158
659 MESODERMAL CELL DIFFERENTIATION 10 26 0.0002247 0.00158
660 ENDOCHONDRAL OSSIFICATION 10 26 0.0002247 0.00158
661 INACTIVATION OF MAPK ACTIVITY 10 26 0.0002247 0.00158
662 POSITIVE REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION 10 26 0.0002247 0.00158
663 NEURAL CREST CELL MIGRATION 15 51 0.0002267 0.001591
664 WNT SIGNALING PATHWAY 60 351 0.0002346 0.001644
665 ENDOCYTOSIS 81 509 0.0002499 0.001749
666 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION 11 31 0.0002524 0.001764
667 POSITIVE REGULATION OF RESPONSE TO WOUNDING 33 162 0.0002552 0.00178
668 MYELOID LEUKOCYTE ACTIVATION 23 98 0.0002589 0.001803
669 NEGATIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 12 36 0.0002619 0.001811
670 REGULATION OF NUCLEOTIDE CATABOLIC PROCESS 12 36 0.0002619 0.001811
671 NEGATIVE REGULATION OF BLOOD CIRCULATION 12 36 0.0002619 0.001811
672 CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 12 36 0.0002619 0.001811
673 REGULATION OF ERYTHROCYTE DIFFERENTIATION 12 36 0.0002619 0.001811
674 INNER EAR MORPHOGENESIS 22 92 0.0002631 0.001816
675 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 21 86 0.0002644 0.001823
676 NEGATIVE REGULATION OF MUSCLE CONTRACTION 9 22 0.0002687 0.001841
677 BONE CELL DEVELOPMENT 9 22 0.0002687 0.001841
678 CENTRAL NERVOUS SYSTEM PROJECTION NEURON AXONOGENESIS 9 22 0.0002687 0.001841
679 CELLULAR RESPONSE TO INTERLEUKIN 6 9 22 0.0002687 0.001841
680 LEUKOCYTE CHEMOTAXIS 26 117 0.000271 0.001855
681 REGULATION OF ORGANELLE ORGANIZATION 165 1178 0.0002774 0.001895
682 CELLULAR RESPONSE TO OXYGEN LEVELS 30 143 0.0002807 0.001915
683 REGULATION OF WNT SIGNALING PATHWAY 54 310 0.0002917 0.001987
684 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 38 197 0.0002933 0.001995
685 VASCULAR ENDOTHELIAL GROWTH FACTOR SIGNALING PATHWAY 7 14 0.0002979 0.002003
686 POSITIVE REGULATION OF VACUOLAR TRANSPORT 7 14 0.0002979 0.002003
687 POSITIVE REGULATION OF FATTY ACID OXIDATION 7 14 0.0002979 0.002003
688 NEGATIVE REGULATION OF OSSIFICATION 18 69 0.0002979 0.002003
689 PERIPHERAL NERVOUS SYSTEM DEVELOPMENT 18 69 0.0002979 0.002003
690 CAMP CATABOLIC PROCESS 7 14 0.0002979 0.002003
691 RESPONSE TO ACTIVITY 18 69 0.0002979 0.002003
692 SYNAPSE ASSEMBLY 18 69 0.0002979 0.002003
693 RESPONSE TO PLATELET DERIVED GROWTH FACTOR 8 18 0.0003005 0.002009
694 MAST CELL MEDIATED IMMUNITY 8 18 0.0003005 0.002009
695 OSTEOBLAST DEVELOPMENT 8 18 0.0003005 0.002009
696 REGULATION OF NUCLEOTIDE METABOLIC PROCESS 40 211 0.0003004 0.002009
697 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL 19 75 0.0003083 0.002058
698 RESPONSE TO METAL ION 57 333 0.0003198 0.002129
699 NEGATIVE REGULATION OF BINDING 28 131 0.0003198 0.002129
700 REGULATION OF ENDOTHELIAL CELL DIFFERENTIATION 10 27 0.0003225 0.002137
701 REGULATION OF ASTROCYTE DIFFERENTIATION 10 27 0.0003225 0.002137
702 CENTRAL NERVOUS SYSTEM NEURON AXONOGENESIS 10 27 0.0003225 0.002137
703 EAR MORPHOGENESIS 25 112 0.0003277 0.002169
704 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 43 233 0.0003343 0.00221
705 NEGATIVE REGULATION OF BMP SIGNALING PATHWAY 13 42 0.0003368 0.002223
706 BLOOD VESSEL REMODELING 11 32 0.0003473 0.002286
707 ADIPOSE TISSUE DEVELOPMENT 11 32 0.0003473 0.002286
708 REGULATION OF PROTEIN AUTOPHOSPHORYLATION 12 37 0.0003497 0.002292
709 IMPORT INTO CELL 12 37 0.0003497 0.002292
710 CAMP MEDIATED SIGNALING 12 37 0.0003497 0.002292
711 NEGATIVE REGULATION OF EPITHELIAL CELL MIGRATION 15 53 0.0003606 0.002357
712 MESONEPHRIC TUBULE MORPHOGENESIS 15 53 0.0003606 0.002357
713 INFLAMMATORY RESPONSE 73 454 0.0003626 0.002367
714 POSITIVE REGULATION OF TRANSPORTER ACTIVITY 19 76 0.0003699 0.002411
715 REGULATION OF VESICLE MEDIATED TRANSPORT 74 462 0.0003727 0.002422
716 NEGATIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 20 82 0.0003727 0.002422
717 REGULATION OF MUSCLE CELL DIFFERENTIATION 31 152 0.000378 0.002453
718 REGULATION OF SEQUESTERING OF CALCIUM ION 24 107 0.000396 0.002563
719 REGULATION OF T CELL DIFFERENTIATION 24 107 0.000396 0.002563
720 NEGATIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 9 23 0.0003992 0.002572
721 DIGESTIVE TRACT MORPHOGENESIS 14 48 0.0004002 0.002572
722 REGULATION OF OSTEOBLAST PROLIFERATION 9 23 0.0003992 0.002572
723 POSITIVE REGULATION OF WOUND HEALING 14 48 0.0004002 0.002572
724 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORT 14 48 0.0004002 0.002572
725 NEGATIVE REGULATION OF CELL CYCLE 70 433 0.0004054 0.002602
726 REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION 23 101 0.0004121 0.002641
727 REGULATION OF SODIUM ION TRANSPORT 19 77 0.0004419 0.002825
728 REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 19 77 0.0004419 0.002825
729 DEFENSE RESPONSE 170 1231 0.0004469 0.002853
730 ALPHA BETA T CELL ACTIVATION 15 54 0.0004499 0.002868
731 ENDOMEMBRANE SYSTEM ORGANIZATION 74 465 0.0004521 0.002878
732 MUSCLE HYPERTROPHY 10 28 0.0004532 0.002881
733 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 30 147 0.0004602 0.00292
734 SUBSTRATE ADHESION DEPENDENT CELL SPREADING 12 38 0.0004612 0.00292
735 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 12 38 0.0004612 0.00292
736 ACTIN FILAMENT ORGANIZATION 34 174 0.0004657 0.002944
737 CELLULAR RESPONSE TO FLUID SHEAR STRESS 8 19 0.0004699 0.002946
738 REGULATION OF CARDIAC MUSCLE CONTRACTION BY REGULATION OF THE RELEASE OF SEQUESTERED CALCIUM ION 8 19 0.0004699 0.002946
739 KIDNEY VASCULATURE DEVELOPMENT 8 19 0.0004699 0.002946
740 REGULATION OF NITRIC OXIDE SYNTHASE BIOSYNTHETIC PROCESS 8 19 0.0004699 0.002946
741 EMBRYONIC DIGESTIVE TRACT DEVELOPMENT 11 33 0.0004704 0.002946
742 NEGATIVE REGULATION OF JNK CASCADE 11 33 0.0004704 0.002946
743 RENAL SYSTEM VASCULATURE DEVELOPMENT 8 19 0.0004699 0.002946
744 REGULATION OF CELLULAR RESPONSE TO STRESS 103 691 0.0004747 0.002968
745 RENAL SYSTEM PROCESS 23 102 0.0004784 0.002988
746 REGULATION OF GLUCOSE IMPORT 16 60 0.0004861 0.003032
747 MEMBRANE ORGANIZATION 129 899 0.0004877 0.003038
748 CALCIUM ION TRANSPORT 41 223 0.0004911 0.003055
749 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 40 216 0.0004922 0.003057
750 CELLULAR RESPONSE TO ALCOHOL 25 115 0.0005001 0.003102
751 NEGATIVE REGULATION OF DENDRITE MORPHOGENESIS 7 15 0.0005064 0.003137
752 INTRACELLULAR RECEPTOR SIGNALING PATHWAY 33 168 0.000508 0.003143
753 CELLULAR RESPONSE TO CYTOKINE STIMULUS 92 606 0.0005107 0.003156
754 ESTABLISHMENT OF PROTEIN LOCALIZATION TO PLASMA MEMBRANE 21 90 0.0005115 0.003156
755 POSITIVE REGULATION OF CELL GROWTH 30 148 0.0005185 0.003195
756 LIPID MODIFICATION 39 210 0.0005422 0.003337
757 REGULATION OF CIRCADIAN RHYTHM 23 103 0.0005539 0.003405
758 REGULATION OF TYROSINE PHOSPHORYLATION OF STAT3 PROTEIN 13 44 0.0005574 0.003422
759 POSITIVE REGULATION OF CELL ACTIVATION 53 311 0.0005658 0.003469
760 REGULATION OF MYELOID CELL APOPTOTIC PROCESS 9 24 0.0005777 0.003519
761 REGULATION OF POSITIVE CHEMOTAXIS 9 24 0.0005777 0.003519
762 REGULATION OF ANOIKIS 9 24 0.0005777 0.003519
763 POSITIVE REGULATION OF CATION TRANSMEMBRANE TRANSPORT 22 97 0.0005777 0.003519
764 REGULATION OF APOPTOTIC SIGNALING PATHWAY 60 363 0.0005747 0.003519
765 REGULATION OF POTASSIUM ION TRANSMEMBRANE TRANSPORT 16 61 0.0005936 0.003606
766 POSITIVE REGULATION OF STEM CELL PROLIFERATION 16 61 0.0005936 0.003606
767 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 40 218 0.0005953 0.003611
768 REPRODUCTION 177 1297 0.0006088 0.003689
769 CARDIAC SEPTUM DEVELOPMENT 20 85 0.0006138 0.003714
770 CELLULAR RESPONSE TO DRUG 17 67 0.0006151 0.003717
771 POSITIVE REGULATION OF HEMOPOIESIS 32 163 0.0006186 0.003729
772 VASCULAR PROCESS IN CIRCULATORY SYSTEM 32 163 0.0006186 0.003729
773 PIGMENT CELL DIFFERENTIATION 10 29 0.0006252 0.003763
774 REGULATION OF MESENCHYMAL CELL PROLIFERATION 11 34 0.0006279 0.003775
775 REGULATION OF SKELETAL MUSCLE TISSUE DEVELOPMENT 14 50 0.0006324 0.003797
776 POSITIVE REGULATION OF PROTEIN IMPORT 23 104 0.0006395 0.003835
777 PEPTIDYL AMINO ACID MODIFICATION 121 841 0.0006512 0.0039
778 REGULATION OF HORMONE SECRETION 46 262 0.0006622 0.003961
779 NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 22 98 0.00067 0.004002
780 EMBRYONIC HEMOPOIESIS 8 20 0.0007091 0.004198
781 ALPHA BETA T CELL DIFFERENTIATION 13 45 0.000707 0.004198
782 VENTRICULAR CARDIAC MUSCLE TISSUE DEVELOPMENT 13 45 0.000707 0.004198
783 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 58 351 0.0007079 0.004198
784 PARTURITION 8 20 0.0007091 0.004198
785 RESPONSE TO MUSCLE ACTIVITY 8 20 0.0007091 0.004198
786 RESPONSE TO LEPTIN 8 20 0.0007091 0.004198
787 FOREBRAIN CELL MIGRATION 16 62 0.0007207 0.004261
788 RETINA DEVELOPMENT IN CAMERA TYPE EYE 27 131 0.0007365 0.004349
789 REGULATION OF TYROSINE PHOSPHORYLATION OF STAT PROTEIN 17 68 0.0007386 0.00435
790 REGULATION OF PHAGOCYTOSIS 17 68 0.0007386 0.00435
791 MESODERM DEVELOPMENT 25 118 0.0007472 0.004395
792 PLACENTA DEVELOPMENT 28 138 0.0007697 0.004522
793 MYELOID LEUKOCYTE MIGRATION 22 99 0.0007749 0.004537
794 POSITIVE REGULATION OF CELL MATRIX ADHESION 12 40 0.0007752 0.004537
795 NEGATIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 12 40 0.0007752 0.004537
796 REGULATION OF PROTEIN COMPLEX ASSEMBLY 61 375 0.0007874 0.004603
797 PHOSPHATIDYLINOSITOL METABOLIC PROCESS 36 193 0.0007983 0.00466
798 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 21 93 0.0008103 0.004724
799 REGULATION OF TRANSFORMING GROWTH FACTOR BETA PRODUCTION 9 25 0.0008165 0.004743
800 CARDIAC RIGHT VENTRICLE MORPHOGENESIS 7 16 0.0008163 0.004743
801 RESPONSE TO EPINEPHRINE 7 16 0.0008163 0.004743
802 REGULATION OF GASTRULATION 11 35 0.000827 0.004798
803 L AMINO ACID IMPORT 6 12 0.0008298 0.004808
804 B CELL ACTIVATION 27 132 0.0008322 0.004816
805 POSITIVE REGULATION OF CALCIUM ION TRANSPORT 23 106 0.0008458 0.004857
806 SMOOTH MUSCLE CELL DIFFERENTIATION 10 30 0.0008476 0.004857
807 NEURON MATURATION 10 30 0.0008476 0.004857
808 NEGATIVE REGULATION OF B CELL ACTIVATION 10 30 0.0008476 0.004857
809 NEGATIVE REGULATION OF INTRACELLULAR STEROID HORMONE RECEPTOR SIGNALING PATHWAY 10 30 0.0008476 0.004857
810 NEGATIVE REGULATION OF CELL MATRIX ADHESION 10 30 0.0008476 0.004857
811 ESTABLISHMENT OF ENDOTHELIAL BARRIER 10 30 0.0008476 0.004857
812 CELLULAR RESPONSE TO VASCULAR ENDOTHELIAL GROWTH FACTOR STIMULUS 10 30 0.0008476 0.004857
813 REGULATION OF PROTEIN POLYMERIZATION 33 173 0.000867 0.004944
814 REGULATION OF FIBROBLAST PROLIFERATION 19 81 0.0008649 0.004944
815 REGULATION OF CELL SHAPE 28 139 0.0008662 0.004944
816 REGULATION OF JUN KINASE ACTIVITY 19 81 0.0008649 0.004944
817 NEGATIVE REGULATION OF NUCLEOTIDE METABOLIC PROCESS 16 63 0.0008704 0.004957
818 POSITIVE REGULATION OF AUTOPHAGY 18 75 0.0008798 0.005004
819 REGULATION OF INTERLEUKIN 10 PRODUCTION 13 46 0.0008891 0.005045
820 POSITIVE REGULATION OF PHAGOCYTOSIS 13 46 0.0008891 0.005045
821 NEGATIVE REGULATION OF INFLAMMATORY RESPONSE 22 100 0.0008936 0.005064
822 POSITIVE REGULATION OF CYTOKINE PRODUCTION 60 370 0.0009353 0.005294
823 REGULATION OF CYTOKINE BIOSYNTHETIC PROCESS 21 94 0.0009387 0.005307
824 SINGLE ORGANISM CELLULAR LOCALIZATION 127 898 0.0009471 0.005348
825 REGULATION OF PEPTIDE SECRETION 38 209 0.0009597 0.005413
826 CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS 35 188 0.0009697 0.005462
827 REGULATION OF MEMBRANE DEPOLARIZATION 12 41 0.0009892 0.005549
828 NEGATIVE REGULATION OF STRESS ACTIVATED MAPK CASCADE 12 41 0.0009892 0.005549
829 NEGATIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 12 41 0.0009892 0.005549
830 REGULATION OF IMMUNE EFFECTOR PROCESS 67 424 0.0009898 0.005549
831 REGULATION OF ERK1 AND ERK2 CASCADE 42 238 0.0009978 0.005587
832 KIDNEY MORPHOGENESIS 19 82 0.001013 0.005667
833 REGULATION OF G PROTEIN COUPLED RECEPTOR PROTEIN SIGNALING PATHWAY 26 127 0.001015 0.005667
834 PHOSPHOLIPID TRANSPORT 15 58 0.00102 0.005693
835 MAST CELL ACTIVATION 8 21 0.001037 0.005761
836 SYMPATHETIC NERVOUS SYSTEM DEVELOPMENT 8 21 0.001037 0.005761
837 REGULATION OF SYNAPTIC VESICLE EXOCYTOSIS 8 21 0.001037 0.005761
838 SIALYLATION 8 21 0.001037 0.005761
839 REGULATION OF NEUROTRANSMITTER TRANSPORT 16 64 0.001046 0.005792
840 REGULATION OF PROTEIN ACETYLATION 16 64 0.001046 0.005792
841 GLYCEROPHOSPHOLIPID METABOLIC PROCESS 50 297 0.001051 0.005813
842 REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION 37 203 0.00106 0.005859
843 HOMEOSTASIS OF NUMBER OF CELLS 33 175 0.001064 0.005871
844 LAMELLIPODIUM ORGANIZATION 11 36 0.001076 0.005916
845 SEMAPHORIN PLEXIN SIGNALING PATHWAY 11 36 0.001076 0.005916
846 T CELL SELECTION 11 36 0.001076 0.005916
847 NEGATIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 21 95 0.001084 0.005956
848 ENTRAINMENT OF CIRCADIAN CLOCK 9 26 0.00113 0.006184
849 RESPONSE TO INTERLEUKIN 6 9 26 0.00113 0.006184
850 HEART GROWTH 9 26 0.00113 0.006184
851 REGULATION OF SYNAPTIC VESICLE TRANSPORT 10 31 0.001131 0.006184
852 POSITIVE REGULATION OF FIBROBLAST PROLIFERATION 14 53 0.001188 0.006475
853 REGULATION OF NITRIC OXIDE BIOSYNTHETIC PROCESS 14 53 0.001188 0.006475
854 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 27 135 0.001187 0.006475
855 CELL FATE SPECIFICATION 17 71 0.001244 0.006768
856 CELLULAR RESPONSE TO RETINOIC ACID 16 65 0.00125 0.006772
857 REGULATION OF CELLULAR CARBOHYDRATE CATABOLIC PROCESS 12 42 0.00125 0.006772
858 POSITIVE REGULATION OF GLUCOSE TRANSPORT 12 42 0.00125 0.006772
859 REGULATION OF CARBOHYDRATE CATABOLIC PROCESS 12 42 0.00125 0.006772
860 REGULATION OF ENERGY HOMEOSTASIS 7 17 0.001259 0.006778
861 REGULATION OF PLATELET AGGREGATION 7 17 0.001259 0.006778
862 REGULATION OF CALCINEURIN NFAT SIGNALING CASCADE 7 17 0.001259 0.006778
863 POSITIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 7 17 0.001259 0.006778
864 DEFINITIVE HEMOPOIESIS 7 17 0.001259 0.006778
865 RESPONSE TO HYDROGEN PEROXIDE 23 109 0.001262 0.00679
866 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 26 129 0.001289 0.006924
867 EYE MORPHOGENESIS 27 136 0.001331 0.007143
868 NEGATIVE REGULATION OF COAGULATION 13 48 0.001372 0.007346
869 COLUMNAR CUBOIDAL EPITHELIAL CELL DEVELOPMENT 13 48 0.001372 0.007346
870 POSITIVE REGULATION OF CATION CHANNEL ACTIVITY 11 37 0.001383 0.007361
871 REGULATION OF SYSTEMIC ARTERIAL BLOOD PRESSURE 19 84 0.001376 0.007361
872 REGULATION OF MEMBRANE LIPID DISTRIBUTION 11 37 0.001383 0.007361
873 POSITIVE REGULATION OF TYROSINE PHOSPHORYLATION OF STAT3 PROTEIN 11 37 0.001383 0.007361
874 AXON EXTENSION 11 37 0.001383 0.007361
875 RELAXATION OF CARDIAC MUSCLE 6 13 0.0014 0.007412
876 PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 6 13 0.0014 0.007412
877 NEGATIVE REGULATION OF MACROPHAGE DERIVED FOAM CELL DIFFERENTIATION 6 13 0.0014 0.007412
878 NEGATIVE REGULATION OF CARDIAC MUSCLE CELL APOPTOTIC PROCESS 6 13 0.0014 0.007412
879 ENDOCRINE SYSTEM DEVELOPMENT 25 123 0.001397 0.007412
880 REGULATION OF ENDOCYTOSIS 36 199 0.001409 0.007451
881 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 32 171 0.00143 0.007553
882 CELLULAR RESPONSE TO STRESS 206 1565 0.001439 0.007593
883 ACTIVIN RECEPTOR SIGNALING PATHWAY 8 22 0.001477 0.007782
884 ENDOCARDIAL CUSHION DEVELOPMENT 10 32 0.001487 0.007819
885 METANEPHRIC NEPHRON DEVELOPMENT 10 32 0.001487 0.007819
886 REGULATION OF RECEPTOR ACTIVITY 24 117 0.00151 0.007922
887 CELLULAR RESPONSE TO STARVATION 24 117 0.00151 0.007922
888 NEGATIVE REGULATION OF DEFENSE RESPONSE 28 144 0.001523 0.00798
889 NEGATIVE REGULATION OF AXON GUIDANCE 9 27 0.001533 0.007981
890 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 9 27 0.001533 0.007981
891 REGULATION OF CATENIN IMPORT INTO NUCLEUS 9 27 0.001533 0.007981
892 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 9 27 0.001533 0.007981
893 SUBSTRATE DEPENDENT CELL MIGRATION 9 27 0.001533 0.007981
894 POSITIVE REGULATION OF POTASSIUM ION TRANSMEMBRANE TRANSPORT 9 27 0.001533 0.007981
895 CELLULAR RESPONSE TO REACTIVE OXYGEN SPECIES 22 104 0.001539 0.007999
896 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 41 236 0.001548 0.00804
897 REGULATION OF PROTEIN CATABOLIC PROCESS 62 393 0.001556 0.00807
898 REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 12 43 0.001566 0.008112
899 PROTEIN STABILIZATION 26 131 0.001624 0.008407
900 SEX DIFFERENTIATION 45 266 0.001643 0.008494
901 AUTOPHAGY 62 394 0.001656 0.008551
902 REGULATION OF LEUKOCYTE APOPTOTIC PROCESS 18 79 0.001666 0.008592
903 CELLULAR MACROMOLECULE LOCALIZATION 166 1234 0.001673 0.008623
904 REGULATION OF NUCLEOSIDE METABOLIC PROCESS 13 49 0.001685 0.008663
905 REGULATION OF ATP METABOLIC PROCESS 13 49 0.001685 0.008663
906 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 24 118 0.001705 0.008756
907 ANTERIOR POSTERIOR PATTERN SPECIFICATION 35 194 0.001708 0.008761
908 POSITIVE REGULATION OF STAT CASCADE 17 73 0.001722 0.008786
909 REGULATION OF CHROMATIN ORGANIZATION 29 152 0.001719 0.008786
910 CELLULAR RESPONSE TO KETONE 17 73 0.001722 0.008786
911 POSITIVE REGULATION OF JAK STAT CASCADE 17 73 0.001722 0.008786
912 REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 17 73 0.001722 0.008786
913 CALCIUM ION TRANSMEMBRANE TRANSPORT 30 159 0.001733 0.008831
914 ODONTOGENESIS 22 105 0.001751 0.008915
915 POSITIVE REGULATION OF POTASSIUM ION TRANSPORT 11 38 0.001758 0.00893
916 REGULATION OF RENAL SYSTEM PROCESS 11 38 0.001758 0.00893
917 ION TRANSPORT 169 1262 0.001851 0.009394
918 CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE 27 139 0.001858 0.009417
919 RESPONSE TO CAFFEINE 7 18 0.001868 0.00946
920 STRIATED MUSCLE CONTRACTION 21 99 0.001876 0.009489
921 DIVALENT INORGANIC CATION TRANSPORT 45 268 0.001913 0.009664
922 PROTEIN LOCALIZATION TO GOLGI APPARATUS 10 33 0.001929 0.009736
923 POLYSACCHARIDE METABOLIC PROCESS 18 80 0.001936 0.009747
924 ADULT LOCOMOTORY BEHAVIOR 18 80 0.001936 0.009747
925 MYELOID CELL DEVELOPMENT 12 44 0.001944 0.009777
926 ESTABLISHMENT OF PROTEIN LOCALIZATION 188 1423 0.001953 0.009814
927 SPINAL CORD DEVELOPMENT 22 106 0.001988 0.00997
928 REGULATION OF GLUCOSE METABOLIC PROCESS 22 106 0.001988 0.00997
NumGOOverlapSizeP ValueAdj. P Value
1 ENZYME BINDING 312 1737 7.091e-21 6.588e-18
2 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 142 629 5.563e-18 2.584e-15
3 KINASE ACTIVITY 174 842 1.157e-17 3.583e-15
4 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 89 328 9.854e-17 2.289e-14
5 PROTEIN KINASE ACTIVITY 140 640 1.617e-16 3.004e-14
6 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 86 315 2.178e-16 3.372e-14
7 CYTOSKELETAL PROTEIN BINDING 165 819 9.883e-16 1.312e-13
8 ACTIN BINDING 98 393 1.187e-15 1.351e-13
9 KINASE BINDING 132 606 1.745e-15 1.351e-13
10 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 219 1199 1.541e-15 1.351e-13
11 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 68 226 1.612e-15 1.351e-13
12 RECEPTOR BINDING 257 1476 1.715e-15 1.351e-13
13 MACROMOLECULAR COMPLEX BINDING 244 1399 8.088e-15 5.78e-13
14 PROTEIN COMPLEX BINDING 176 935 7.554e-14 5.013e-12
15 GROWTH FACTOR BINDING 44 123 1.984e-13 1.229e-11
16 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 182 992 3.11e-13 1.806e-11
17 PROTEIN DOMAIN SPECIFIC BINDING 126 624 2.39e-12 1.306e-10
18 REGULATORY REGION NUCLEIC ACID BINDING 151 818 2.289e-11 1.181e-09
19 COLLAGEN BINDING 28 65 2.789e-11 1.364e-09
20 GLYCOSAMINOGLYCAN BINDING 54 205 3.531e-10 1.64e-08
21 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 30 81 4.955e-10 2.192e-08
22 TRANSCRIPTION FACTOR BINDING 103 524 1.191e-09 5.028e-08
23 CELL ADHESION MOLECULE BINDING 49 186 2.274e-09 9.185e-08
24 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 56 228 2.807e-09 1.087e-07
25 PROTEIN SERINE THREONINE KINASE ACTIVITY 90 445 3.137e-09 1.166e-07
26 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 68 303 3.532e-09 1.262e-07
27 MOLECULAR FUNCTION REGULATOR 213 1353 6.749e-09 2.322e-07
28 CYTOKINE BINDING 30 92 1.586e-08 5.263e-07
29 SMAD BINDING 25 72 6.071e-08 1.945e-06
30 SEQUENCE SPECIFIC DNA BINDING 166 1037 1.161e-07 3.596e-06
31 RIBONUCLEOTIDE BINDING 270 1860 1.421e-07 4.258e-06
32 CALCIUM ION BINDING 120 697 1.589e-07 4.612e-06
33 HEPARIN BINDING 40 157 1.745e-07 4.911e-06
34 PROTEIN DIMERIZATION ACTIVITY 179 1149 2.451e-07 6.697e-06
35 BINDING BRIDGING 42 173 3.636e-07 9.651e-06
36 INTEGRIN BINDING 30 105 4.273e-07 1.103e-05
37 PROTEIN TYROSINE KINASE ACTIVITY 42 176 5.972e-07 1.459e-05
38 GLYCOPROTEIN BINDING 29 101 5.908e-07 1.459e-05
39 CORE PROMOTER PROXIMAL REGION DNA BINDING 72 371 6.125e-07 1.459e-05
40 TRANSFORMING GROWTH FACTOR BETA BINDING 10 16 9.407e-07 2.185e-05
41 DOUBLE STRANDED DNA BINDING 125 764 1.436e-06 3.255e-05
42 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 21 64 1.969e-06 4.355e-05
43 PLATELET DERIVED GROWTH FACTOR BINDING 8 11 2.282e-06 4.929e-05
44 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 22 70 2.556e-06 5.397e-05
45 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 100 588 2.985e-06 6.163e-05
46 ACTIN FILAMENT BINDING 31 121 3.598e-06 7.266e-05
47 SH3 DOMAIN BINDING 30 116 4.176e-06 8.255e-05
48 SULFUR COMPOUND BINDING 49 234 4.292e-06 8.306e-05
49 IDENTICAL PROTEIN BINDING 180 1209 4.423e-06 8.386e-05
50 ADENYL NUCLEOTIDE BINDING 218 1514 4.566e-06 8.484e-05
51 ION CHANNEL BINDING 29 111 4.83e-06 8.798e-05
52 SIGNALING ADAPTOR ACTIVITY 22 74 7.081e-06 0.0001265
53 PROTEIN HOMODIMERIZATION ACTIVITY 116 722 8.192e-06 0.0001436
54 ZINC ION BINDING 171 1155 1.074e-05 0.0001848
55 EXTRACELLULAR MATRIX STRUCTURAL CONSTITUENT 22 76 1.139e-05 0.0001923
56 RECEPTOR SIGNALING PROTEIN ACTIVITY 38 172 1.388e-05 0.0002303
57 CALMODULIN BINDING 39 179 1.516e-05 0.000247
58 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE ACTIVITY 9 17 2.175e-05 0.0003484
59 PHOSPHOLIPID TRANSPORTER ACTIVITY 16 48 2.58e-05 0.0004062
60 PHOSPHATIDYLINOSITOL 3 KINASE BINDING 12 30 3.361e-05 0.0005204
61 PROTEIN HETERODIMERIZATION ACTIVITY 79 468 4.138e-05 0.0006302
62 PHOSPHOLIPID BINDING 64 360 4.553e-05 0.0006822
63 CYCLIC NUCLEOTIDE BINDING 13 36 5.68e-05 0.0008375
64 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC BINDING 23 90 6.512e-05 0.0009387
65 CAMP BINDING 10 23 6.568e-05 0.0009387
66 LIPID BINDING 103 657 7.076e-05 0.000996
67 TRANSITION METAL ION BINDING 196 1400 7.645e-05 0.00106
68 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II ACTIVATING TRANSCRIPTION FACTOR BINDING 16 53 0.0001004 0.001372
69 TRANSCRIPTION FACTOR ACTIVITY DIRECT LIGAND REGULATED SEQUENCE SPECIFIC DNA BINDING 15 48 0.0001063 0.001431
70 PHOSPHOLIPID TRANSLOCATING ATPASE ACTIVITY 8 16 0.0001079 0.001431
71 VOLTAGE GATED SODIUM CHANNEL ACTIVITY 9 20 0.000111 0.001452
72 STEROID HORMONE RECEPTOR ACTIVITY 17 59 0.0001173 0.001513
73 HORMONE BINDING 18 65 0.0001313 0.001651
74 ENZYME REGULATOR ACTIVITY 140 959 0.0001315 0.001651
75 BETA CATENIN BINDING 21 84 0.000186 0.002304
76 NUCLEOSIDE TRIPHOSPHATASE REGULATOR ACTIVITY 57 329 0.0002326 0.002843
77 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 34 168 0.0002361 0.002848
78 WNT PROTEIN BINDING 11 31 0.0002524 0.003001
79 PHOSPHATASE BINDING 33 162 0.0002552 0.003001
80 RECEPTOR SIGNALING PROTEIN SERINE THREONINE KINASE ACTIVITY 22 92 0.0002631 0.003055
81 TUBULIN BINDING 49 273 0.0002667 0.003059
82 PHOSPHORIC ESTER HYDROLASE ACTIVITY 62 368 0.0002796 0.003168
83 SH3 SH2 ADAPTOR ACTIVITY 15 52 0.000287 0.003212
84 HISTONE DEACETYLASE BINDING 24 105 0.0002941 0.003252
85 CHEMOREPELLENT ACTIVITY 10 27 0.0003225 0.003524
86 PROTEIN KINASE A BINDING 13 42 0.0003368 0.003639
87 PHOSPHATIDYLINOSITOL BINDING 38 200 0.0004005 0.004276
88 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 28 133 0.000415 0.004381
89 GROWTH FACTOR ACTIVITY 32 160 0.0004413 0.004562
90 RHO GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 19 77 0.0004419 0.004562
91 CORECEPTOR ACTIVITY 12 38 0.0004612 0.004658
92 TRANSCRIPTION COACTIVATOR BINDING 6 11 0.0004567 0.004658
93 X3 5 CYCLIC AMP PHOSPHODIESTERASE ACTIVITY 7 15 0.0005064 0.005004
94 PLATELET DERIVED GROWTH FACTOR RECEPTOR BINDING 7 15 0.0005064 0.005004
95 SH2 DOMAIN BINDING 10 29 0.0006252 0.006076
96 UBIQUITIN LIKE PROTEIN CONJUGATING ENZYME BINDING 11 34 0.0006279 0.006076
97 PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 34 178 0.0007125 0.006824
98 PROTEIN COMPLEX SCAFFOLD 17 68 0.0007386 0.006931
99 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 23 105 0.0007364 0.006931
100 CYTOKINE RECEPTOR BINDING 47 271 0.0007662 0.007118
101 EXTRACELLULAR MATRIX BINDING 14 51 0.0007859 0.007229
102 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ACTIVITY 9 25 0.0008165 0.007437
103 PROTEIN SERINE THREONINE KINASE INHIBITOR ACTIVITY 10 30 0.0008476 0.007644
104 G PROTEIN COUPLED RECEPTOR BINDING 45 259 0.0009421 0.008416
105 PROTEIN PHOSPHATASE BINDING 25 120 0.0009657 0.008544
106 METAL ION TRANSMEMBRANE TRANSPORTER ACTIVITY 66 417 0.00103 0.008924
107 SIALYLTRANSFERASE ACTIVITY 8 21 0.001037 0.008924
108 ALPHA ACTININ BINDING 8 21 0.001037 0.008924
109 CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 26 128 0.001145 0.009666
110 CYTOKINE RECEPTOR ACTIVITY 20 89 0.001137 0.009666
NumGOOverlapSizeP ValueAdj. P Value
1 CELL JUNCTION 244 1151 3.252e-26 1.899e-23
2 ANCHORING JUNCTION 119 489 7.409e-18 2.163e-15
3 MEMBRANE REGION 216 1134 2.09e-17 4.068e-15
4 NEURON PROJECTION 187 942 5.02e-17 7.33e-15
5 CELL SURFACE 158 757 1.568e-16 1.831e-14
6 SYNAPSE 157 754 2.459e-16 2.393e-14
7 INTRINSIC COMPONENT OF PLASMA MEMBRANE 283 1649 3.514e-16 2.932e-14
8 NEURON PART 230 1265 4.696e-16 3.428e-14
9 MEMBRANE MICRODOMAIN 80 288 8.431e-16 5.471e-14
10 CELL SUBSTRATE JUNCTION 99 398 1.008e-15 5.888e-14
11 ACTIN CYTOSKELETON 106 444 1.972e-15 1.047e-13
12 CELL PROJECTION 297 1786 4.221e-15 2.054e-13
13 CELL LEADING EDGE 89 350 7.105e-15 3.192e-13
14 SOMATODENDRITIC COMPARTMENT 131 650 9.966e-13 4.157e-11
15 CELL CELL JUNCTION 89 383 1.831e-12 7.128e-11
16 EXTRACELLULAR MATRIX 95 426 4.151e-12 1.515e-10
17 VACUOLE 202 1180 1.244e-11 4.274e-10
18 PROTEINACEOUS EXTRACELLULAR MATRIX 82 356 2.205e-11 7.153e-10
19 AXON 89 418 2.578e-10 7.867e-09
20 DENDRITE 94 451 2.694e-10 7.867e-09
21 LAMELLIPODIUM 48 172 4.05e-10 1.126e-08
22 POSTSYNAPSE 82 378 5.095e-10 1.294e-08
23 RECEPTOR COMPLEX 74 327 4.891e-10 1.294e-08
24 PLASMA MEMBRANE PROTEIN COMPLEX 102 510 5.336e-10 1.298e-08
25 PLASMA MEMBRANE REGION 161 929 6.961e-10 1.626e-08
26 EXCITATORY SYNAPSE 51 197 2.075e-09 4.661e-08
27 CONTRACTILE FIBER 53 211 3.2e-09 6.921e-08
28 SYNAPSE PART 114 610 3.361e-09 7.01e-08
29 CELL PROJECTION PART 160 946 4.678e-09 9.42e-08
30 ACTIN BASED CELL PROJECTION 47 181 7.907e-09 1.539e-07
31 I BAND 36 121 9.655e-09 1.819e-07
32 SIDE OF MEMBRANE 85 428 2.06e-08 3.76e-07
33 FILOPODIUM 30 94 2.768e-08 4.899e-07
34 SITE OF POLARIZED GROWTH 40 149 3.728e-08 6.403e-07
35 CORTICAL CYTOSKELETON 27 81 4.867e-08 8.121e-07
36 T TUBULE 19 45 6.35e-08 1.03e-06
37 EXTRACELLULAR MATRIX COMPONENT 35 125 8.384e-08 1.289e-06
38 SARCOLEMMA 35 125 8.384e-08 1.289e-06
39 AXON PART 51 219 8.999e-08 1.348e-06
40 BASAL PART OF CELL 20 51 1.261e-07 1.841e-06
41 ENDOSOME 133 793 1.603e-07 2.283e-06
42 GOLGI APPARATUS 217 1445 2.228e-07 3.098e-06
43 CELL CORTEX 53 238 2.374e-07 3.224e-06
44 CELL CORTEX PART 33 119 2.49e-07 3.305e-06
45 CORTICAL ACTIN CYTOSKELETON 21 58 3.044e-07 3.95e-06
46 RUFFLE 39 156 4.199e-07 5.331e-06
47 PERINUCLEAR REGION OF CYTOPLASM 109 642 1.172e-06 1.456e-05
48 CYTOSKELETON 277 1967 1.361e-06 1.655e-05
49 MAIN AXON 20 58 1.421e-06 1.694e-05
50 CELL BODY 88 494 1.721e-06 2.01e-05
51 PLATELET ALPHA GRANULE 23 75 2.448e-06 2.804e-05
52 INTRACELLULAR VESICLE 187 1259 3.329e-06 3.738e-05
53 ACTOMYOSIN 20 62 4.622e-06 5.093e-05
54 ENDOPLASMIC RETICULUM 232 1631 5.332e-06 5.766e-05
55 PROTEIN COMPLEX INVOLVED IN CELL ADHESION 13 30 5.497e-06 5.837e-05
56 LYTIC VACUOLE 90 526 7.204e-06 7.513e-05
57 CELL CELL CONTACT ZONE 20 64 7.959e-06 8.155e-05
58 PLASMA MEMBRANE RECEPTOR COMPLEX 39 175 8.677e-06 8.736e-05
59 CYTOPLASMIC REGION 56 287 8.865e-06 8.775e-05
60 PLASMA MEMBRANE RAFT 24 86 9.257e-06 9.01e-05
61 BASEMENT MEMBRANE 25 93 1.247e-05 0.0001194
62 INTERCALATED DISC 17 51 1.451e-05 0.0001367
63 EXTERNAL SIDE OF PLASMA MEMBRANE 48 238 1.539e-05 0.0001427
64 BASAL PLASMA MEMBRANE 13 33 1.924e-05 0.0001756
65 NEURON SPINE 29 121 2.882e-05 0.000259
66 APICAL JUNCTION COMPLEX 30 128 3.34e-05 0.0002955
67 ACTIN FILAMENT 20 70 3.468e-05 0.0003023
68 CATION CHANNEL COMPLEX 36 167 4.024e-05 0.0003456
69 CYTOPLASMIC SIDE OF MEMBRANE 36 170 5.966e-05 0.000505
70 COMPLEX OF COLLAGEN TRIMERS 10 23 6.568e-05 0.0005479
71 EXTRINSIC COMPONENT OF MEMBRANE 48 252 7.049e-05 0.0005798
72 MICROVILLUS 20 75 0.0001012 0.0008207
73 VACUOLAR PART 106 694 0.0001577 0.001262
74 PLATELET ALPHA GRANULE LUMEN 16 55 0.0001631 0.001287
75 SYNAPTIC MEMBRANE 48 261 0.0001702 0.001325
76 SODIUM CHANNEL COMPLEX 8 17 0.0001844 0.001417
77 PROTEIN KINASE COMPLEX 22 90 0.0001877 0.001424
78 NEURON PROJECTION TERMINUS 28 129 0.0002445 0.00183
79 BASOLATERAL PLASMA MEMBRANE 40 211 0.0003004 0.002166
80 VOLTAGE GATED SODIUM CHANNEL COMPLEX 7 14 0.0002979 0.002166
81 INTERSTITIAL MATRIX 7 14 0.0002979 0.002166
82 TRANSCRIPTION FACTOR COMPLEX 52 298 0.000358 0.00255
83 LYSOSOMAL LUMEN 21 88 0.0003703 0.002574
84 COLLAGEN TRIMER 21 88 0.0003703 0.002574
85 EXTRACELLULAR SPACE 188 1376 0.00039 0.00268
86 ENDOPLASMIC RETICULUM LUMEN 38 201 0.0004433 0.00301
87 EARLY ENDOSOME 52 301 0.0004573 0.00307
88 LEADING EDGE MEMBRANE 28 134 0.0004714 0.003128
89 APICAL PART OF CELL 60 361 0.0004977 0.003266
90 GOLGI APPARATUS PART 128 893 0.0005349 0.003471
91 PRESYNAPTIC ACTIVE ZONE 10 29 0.0006252 0.004012
92 EXTRINSIC COMPONENT OF CYTOPLASMIC SIDE OF PLASMA MEMBRANE 22 98 0.00067 0.004253
93 SARCOPLASM 17 68 0.0007386 0.004638
94 BANDED COLLAGEN FIBRIL 6 12 0.0008298 0.005155
95 ACTIN FILAMENT BUNDLE 15 57 0.0008393 0.00516
96 MYELIN SHEATH 32 168 0.001055 0.006419
97 PRESYNAPSE 48 283 0.001112 0.006692
98 GOLGI MEMBRANE 102 703 0.001268 0.007557
99 MEMBRANE PROTEIN COMPLEX 141 1020 0.001293 0.007629
100 NEUROMUSCULAR JUNCTION 14 54 0.001447 0.008449
101 SECRETORY GRANULE LUMEN 19 85 0.001596 0.009228

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Focal_adhesion_hsa04510 58 199 8.578e-13 4.461e-11
2 PI3K_Akt_signaling_pathway_hsa04151 78 352 4.761e-10 1.238e-08
3 cGMP_PKG_signaling_pathway_hsa04022 45 163 2.059e-09 3.569e-08
4 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 40 139 4.338e-09 5.124e-08
5 Cell_adhesion_molecules_.CAMs._hsa04514 41 145 4.927e-09 5.124e-08
6 MAPK_signaling_pathway_hsa04010 64 295 3.968e-08 3.439e-07
7 Regulation_of_actin_cytoskeleton_hsa04810 49 208 1.095e-07 8.132e-07
8 Rap1_signaling_pathway_hsa04015 48 206 2.09e-07 1.359e-06
9 Apelin_signaling_pathway_hsa04371 35 137 9.358e-07 5.407e-06
10 FoxO_signaling_pathway_hsa04068 33 132 3.165e-06 1.646e-05
11 Phospholipase_D_signaling_pathway_hsa04072 35 146 4.503e-06 2.129e-05
12 Ras_signaling_pathway_hsa04014 48 232 7.543e-06 3.269e-05
13 TNF_signaling_pathway_hsa04668 28 108 8.198e-06 3.279e-05
14 ECM_receptor_interaction_hsa04512 23 82 1.289e-05 4.786e-05
15 Cellular_senescence_hsa04218 36 160 1.515e-05 5.253e-05
16 Jak_STAT_signaling_pathway_hsa04630 36 162 2.02e-05 6.565e-05
17 AMPK_signaling_pathway_hsa04152 29 121 2.882e-05 8.816e-05
18 cAMP_signaling_pathway_hsa04024 41 198 3.305e-05 9.548e-05
19 Wnt_signaling_pathway_hsa04310 32 146 7.531e-05 0.0002061
20 Hippo_signaling_pathway_multiple_species_hsa04392 11 29 0.0001266 0.0003291
21 Adherens_junction_hsa04520 19 72 0.0001738 0.0004302
22 TGF_beta_signaling_pathway_hsa04350 21 84 0.000186 0.0004397
23 Gap_junction_hsa04540 21 88 0.0003703 0.0008372
24 Hippo_signaling_pathway_hsa04390 31 154 0.0004787 0.001037
25 Calcium_signaling_pathway_hsa04020 35 182 0.0005276 0.001097
26 Cytokine_cytokine_receptor_interaction_hsa04060 47 270 0.0007059 0.001412
27 Tight_junction_hsa04530 32 170 0.001294 0.002492
28 HIF_1_signaling_pathway_hsa04066 19 100 0.01035 0.01923
29 p53_signaling_pathway_hsa04115 14 68 0.01306 0.02341
30 Phosphatidylinositol_signaling_system_hsa04070 18 99 0.01902 0.03296
31 mTOR_signaling_pathway_hsa04150 25 151 0.02048 0.03435
32 ErbB_signaling_pathway_hsa04012 15 85 0.03858 0.0627
33 Mitophagy_animal_hsa04137 12 65 0.04466 0.07038
34 Sphingolipid_signaling_pathway_hsa04071 19 118 0.05032 0.07697
35 Autophagy_animal_hsa04140 20 128 0.0592 0.08784
36 Phagosome_hsa04145 23 152 0.06172 0.08784
37 Hedgehog_signaling_pathway_hsa04340 9 47 0.0625 0.08784
38 Oocyte_meiosis_hsa04114 19 124 0.07562 0.1035
39 Endocytosis_hsa04144 33 244 0.1063 0.1418
40 NF_kappa_B_signaling_pathway_hsa04064 14 95 0.1444 0.1877
41 ABC_transporters_hsa02010 7 45 0.2098 0.266
42 Apoptosis_hsa04210 18 138 0.2357 0.2918
43 Lysosome_hsa04142 16 123 0.2557 0.3092
44 Necroptosis_hsa04217 20 164 0.3211 0.3795
45 Cell_cycle_hsa04110 15 124 0.3654 0.4223
46 Notch_signaling_pathway_hsa04330 6 48 0.4207 0.4756
47 VEGF_signaling_pathway_hsa04370 7 59 0.4596 0.4981
48 Neuroactive_ligand_receptor_interaction_hsa04080 31 278 0.4598 0.4981
49 Ferroptosis_hsa04216 4 40 0.6424 0.6818
50 Peroxisome_hsa04146 4 83 0.9835 0.9835

Quest ID: 79fc73fdae25d1c9f432b10b89f8c30d