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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-496 ABCA13 0.55 0.60838 1.28 0.26041 miRanda -0.29 0.0197 NA
2 hsa-miR-543 ABCA13 -0.29 0.65642 1.28 0.26041 miRanda -0.44 0.00099 NA
3 hsa-miR-496 ACOT9 0.55 0.60838 -0.92 0.7285 miRanda -0.22 0 NA
4 hsa-miR-496 ACSM1 0.55 0.60838 -0.69 0.40934 miRanda -0.31 0.00051 NA
5 hsa-miR-543 ACSM3 -0.29 0.65642 -0.23 0.89918 miRanda -0.19 0.02145 NA
6 hsa-miR-543 ACSS1 -0.29 0.65642 -1.32 0.64713 miRanda -0.19 0.00532 NA
7 hsa-miR-543 ACTG2 -0.29 0.65642 0.03 0.98974 miRanda -0.36 0.01279 NA
8 hsa-miR-496 ACTR3 0.55 0.60838 -0.76 0.84655 miRanda -0.1 0.00028 NA
9 hsa-miR-496 ADAM28 0.55 0.60838 -1.46 0.61423 miRanda -0.43 1.0E-5 NA
10 hsa-miR-543 ADAM28 -0.29 0.65642 -1.46 0.61423 miRanda -0.52 0 NA
11 hsa-miR-543 ADAM9 -0.29 0.65642 -0.36 0.92876 miRanda -0.2 0.00126 NA
12 hsa-miR-496 ADAMTS6 0.55 0.60838 -0.6 0.59783 miRanda -0.23 0.00039 NA
13 hsa-miR-496 ADAMTSL5 0.55 0.60838 0.17 0.90384 miRanda -0.44 0 NA
14 hsa-miR-543 ADAT2 -0.29 0.65642 -0.42 0.76827 miRanda -0.11 0.01486 NA
15 hsa-miR-543 ADD3 -0.29 0.65642 -0.44 0.90001 miRanda -0.13 0.0027 NA
16 hsa-miR-496 ADORA2B 0.55 0.60838 1.45 0.33396 miRanda -0.15 0.03225 NA
17 hsa-miR-543 ADSS -0.29 0.65642 0.2 0.94898 miRanda -0.13 2.0E-5 NA
18 hsa-miR-543 AFAP1L2 -0.29 0.65642 -0.63 0.81741 miRanda -0.23 0.00015 NA
19 hsa-miR-496 AGMAT 0.55 0.60838 0.11 0.91872 miRanda -0.16 0.03277 NA
20 hsa-miR-543 AGR2 -0.29 0.65642 4.07 0.36748 miRanda -0.81 0 NA
21 hsa-miR-543 AGR3 -0.29 0.65642 1.7 0.52011 miRanda -0.69 1.0E-5 NA
22 hsa-miR-543 AHNAK -0.29 0.65642 -0.09 0.98554 miRanda -0.15 0.00219 NA
23 hsa-miR-375 AHR 3.94 0.60651 -0.01 0.99721 miRanda -0.1 0.00054 NA
24 hsa-miR-496 AHR 0.55 0.60838 -0.01 0.99721 miRanda -0.13 0.00786 NA
25 hsa-miR-543 AHR -0.29 0.65642 -0.01 0.99721 miRanda -0.2 0.00019 NA
26 hsa-miR-543 AIM1 -0.29 0.65642 -1.12 0.69647 miRanda -0.21 0.00586 NA
27 hsa-miR-543 AIM1L -0.29 0.65642 1.83 0.35987 miRanda -0.73 0 NA
28 hsa-miR-543 AKAP5 -0.29 0.65642 -1.34 0.20418 miRanda -0.13 0.02031 NA
29 hsa-miR-496 ALG3 0.55 0.60838 0.42 0.88028 miRanda -0.17 0 NA
30 hsa-miR-543 ANO6 -0.29 0.65642 -0.6 0.86077 miRanda -0.11 0.01691 NA
31 hsa-miR-543 ANTXR1 -0.29 0.65642 -0.72 0.85999 miRanda -0.18 0.03347 NA
32 hsa-miR-543 ANXA2P3 -0.29 0.65642 -1.19 0.20049 miRanda -0.23 0.00749 NA
33 hsa-miR-496 ANXA4 0.55 0.60838 -0.24 0.95893 miRanda -0.23 0.00158 NA
34 hsa-miR-496 APBB1IP 0.55 0.60838 -2.51 0.20132 miRanda -0.17 0.03618 NA
35 hsa-miR-543 AQP9 -0.29 0.65642 -2.92 0.0592 miRanda -0.31 0.00705 NA
36 hsa-miR-375 ARAP2 3.94 0.60651 -0.75 0.76433 miRanda -0.13 3.0E-5 NA
37 hsa-miR-496 ARHGAP11A 0.55 0.60838 0.46 0.80083 miRanda -0.17 0.00062 NA
38 hsa-miR-543 ARHGAP11B -0.29 0.65642 -0.29 0.66969 miRanda -0.19 0.01267 NA
39 hsa-miR-543 ARHGAP12 -0.29 0.65642 0.06 0.98334 miRanda -0.12 0.00205 NA
40 hsa-miR-496 ARHGAP27 0.55 0.60838 -0.4 0.90004 miRanda -0.28 0 NA
41 hsa-miR-543 ARHGAP32 -0.29 0.65642 0.77 0.80338 miRanda -0.19 0.00013 NA
42 hsa-miR-543 ARHGAP6 -0.29 0.65642 0.01 0.99291 miRanda -0.17 0.00954 NA
43 hsa-miR-375 ARHGDIB 3.94 0.60651 -1.53 0.67706 miRanda -0.1 0.00041 NA
44 hsa-miR-543 ARHGEF2 -0.29 0.65642 -0.51 0.87953 miRanda -0.19 0 NA
45 hsa-miR-375 ARL14 3.94 0.60651 0.61 0.81063 miRanda -0.23 0.00681 NA
46 hsa-miR-543 ARL14 -0.29 0.65642 0.61 0.81063 miRanda -0.91 0 NA
47 hsa-miR-543 ARMC10 -0.29 0.65642 0.08 0.97417 miRanda -0.11 5.0E-5 NA
48 hsa-miR-543 ARPC1B -0.29 0.65642 -0.87 0.83457 miRanda -0.15 0.00019 NA
49 hsa-miR-496 ASAP2 0.55 0.60838 0.83 0.79826 miRanda -0.11 0.0381 NA
50 hsa-miR-543 ASAP2 -0.29 0.65642 0.83 0.79826 miRanda -0.21 9.0E-5 NA
51 hsa-miR-543 ASF1B -0.29 0.65642 0.26 0.89226 miRanda -0.26 5.0E-5 NA
52 hsa-miR-543 ASPH -0.29 0.65642 0.46 0.90891 miRanda -0.17 0.00504 NA
53 hsa-miR-543 ASPN -0.29 0.65642 0.21 0.94844 miRanda -0.24 0.01215 NA
54 hsa-miR-543 ATF7IP2 -0.29 0.65642 -1.06 0.53248 miRanda -0.26 4.0E-5 NA
55 hsa-miR-375 ATP10A 3.94 0.60651 -0.6 0.77679 miRanda -0.16 1.0E-5 NA
56 hsa-miR-543 ATP10A -0.29 0.65642 -0.6 0.77679 miRanda -0.15 0.02231 NA
57 hsa-miR-496 ATP10B 0.55 0.60838 0.12 0.9634 miRanda -0.54 0.00033 NA
58 hsa-miR-543 ATP11B -0.29 0.65642 -0.31 0.92367 miRanda -0.14 0.00019 NA
59 hsa-miR-543 ATP6V0D2 -0.29 0.65642 -2.18 0.00523 miRanda -0.3 0.00118 NA
60 hsa-miR-496 AVL9 0.55 0.60838 0.07 0.97309 miRanda -0.11 0.00245 NA
61 hsa-miR-543 AVL9 -0.29 0.65642 0.07 0.97309 miRanda -0.14 0.00014 NA
62 hsa-miR-543 B2M -0.29 0.65642 -0.63 0.91369 miRanda -0.13 0.00087 NA
63 hsa-miR-543 B3GNT5 -0.29 0.65642 0.43 0.87244 miRanda -0.17 0.00292 NA
64 hsa-miR-543 B3GNT6 -0.29 0.65642 0.67 0.72571 miRanda -0.87 0.00015 NA
65 hsa-miR-496 BAIAP2L1 0.55 0.60838 1.27 0.71967 miRanda -0.15 0.02439 NA
66 hsa-miR-543 BARX2 -0.29 0.65642 -0.6 0.77231 miRanda -0.47 9.0E-5 NA
67 hsa-miR-543 BAZ1A -0.29 0.65642 -0.9 0.7528 miRanda -0.15 0.00065 NA
68 hsa-miR-375 BCL11B 3.94 0.60651 -1.34 0.42572 miRanda -0.11 0.01666 NA
69 hsa-miR-375 BCL2L14 3.94 0.60651 -0.38 0.81716 miRanda -0.2 0.00408 NA
70 hsa-miR-496 BCL2L14 0.55 0.60838 -0.38 0.81716 miRanda -0.69 0 NA
71 hsa-miR-543 BCL2L14 -0.29 0.65642 -0.38 0.81716 miRanda -0.76 0 NA
72 hsa-miR-375 BCL6 3.94 0.60651 -0.92 0.7625 miRanda -0.14 0 NA
73 hsa-miR-543 BCL6 -0.29 0.65642 -0.92 0.7625 miRanda -0.12 0.01083 NA
74 hsa-miR-543 BDNF -0.29 0.65642 0.42 0.57837 miRanda -0.18 0.03626 NA
75 hsa-miR-543 BHLHE40 -0.29 0.65642 0.24 0.95761 miRanda -0.16 0.01932 NA
76 hsa-miR-543 BID -0.29 0.65642 -0.12 0.96368 miRanda -0.1 0.00802 NA
77 hsa-miR-496 BIN3 0.55 0.60838 0.11 0.96472 miRanda -0.1 0.00273 NA
78 hsa-miR-375 BIRC5 3.94 0.60651 0.4 0.79598 miRanda -0.27 0 NA
79 hsa-miR-543 BRI3 -0.29 0.65642 -0.14 0.96667 miRanda -0.12 0.00056 NA
80 hsa-miR-496 BTNL3 0.55 0.60838 -1.79 0.37933 miRanda -0.48 0.02633 NA
81 hsa-miR-543 BUB1 -0.29 0.65642 -0.03 0.98544 miRanda -0.31 9.0E-5 NA
82 hsa-miR-543 BUB1B -0.29 0.65642 0.31 0.84796 miRanda -0.21 0.00376 NA
83 hsa-miR-496 BZW2 0.55 0.60838 0.15 0.96074 miRanda -0.15 1.0E-5 NA
84 hsa-miR-543 BZW2 -0.29 0.65642 0.15 0.96074 miRanda -0.17 1.0E-5 NA
85 hsa-miR-543 CAB39 -0.29 0.65642 -0.23 0.94628 miRanda -0.11 0.00016 NA
86 hsa-miR-543 CAMK2N1 -0.29 0.65642 1.67 0.64627 miRanda -0.15 0.00572 NA
87 hsa-miR-543 CAP1 -0.29 0.65642 -0.58 0.89508 miRanda -0.13 0.00033 NA
88 hsa-miR-496 CAPG 0.55 0.60838 -1.57 0.69914 miRanda -0.46 0 NA
89 hsa-miR-496 CARD14 0.55 0.60838 0.14 0.87137 miRanda -0.24 0.00091 NA
90 hsa-miR-543 CARD14 -0.29 0.65642 0.14 0.87137 miRanda -0.33 2.0E-5 NA
91 hsa-miR-496 CASP4 0.55 0.60838 -0.96 0.75012 miRanda -0.2 0 NA
92 hsa-miR-543 CASP4 -0.29 0.65642 -0.96 0.75012 miRanda -0.2 0 NA
93 hsa-miR-543 CASP7 -0.29 0.65642 -0.23 0.93464 miRanda -0.16 6.0E-5 NA
94 hsa-miR-543 CASP8 -0.29 0.65642 -1.07 0.67507 miRanda -0.23 1.0E-5 NA
95 hsa-miR-543 CAST -0.29 0.65642 -0 0.99966 miRanda -0.13 0.00026 NA
96 hsa-miR-543 CBLB -0.29 0.65642 -0.67 0.79551 miRanda -0.11 0.00076 NA
97 hsa-miR-496 CCDC84 0.55 0.60838 -0.16 0.91539 miRanda -0.12 0.01041 NA
98 hsa-miR-543 CCDC88C -0.29 0.65642 -1.33 0.61736 miRanda -0.25 4.0E-5 NA
99 hsa-miR-543 CCK -0.29 0.65642 2.35 0.15308 miRanda -0.78 5.0E-5 NA
100 hsa-miR-543 CCL11 -0.29 0.65642 -0.72 0.509 miRanda -0.32 0.00456 NA
101 hsa-miR-496 CCL20 0.55 0.60838 -0.66 0.76681 miRanda -0.62 1.0E-5 NA
102 hsa-miR-543 CCL22 -0.29 0.65642 -1.79 0.28612 miRanda -0.42 0.00052 NA
103 hsa-miR-496 CCL28 0.55 0.60838 -2.18 0.2159 miRanda -0.34 0.00093 NA
104 hsa-miR-496 CCNB1 0.55 0.60838 0.85 0.7071 miRanda -0.13 0.0144 NA
105 hsa-miR-543 CCNB1 -0.29 0.65642 0.85 0.7071 miRanda -0.14 0.01214 NA
106 hsa-miR-543 CCNF -0.29 0.65642 0.14 0.93342 miRanda -0.14 0.00354 NA
107 hsa-miR-543 CCNI2 -0.29 0.65642 -0.19 0.84244 miRanda -0.34 1.0E-5 NA
108 hsa-miR-496 CD2AP 0.55 0.60838 0.05 0.98919 miRanda -0.1 0.01373 NA
109 hsa-miR-543 CD2AP -0.29 0.65642 0.05 0.98919 miRanda -0.19 3.0E-5 NA
110 hsa-miR-543 CD300LF -0.29 0.65642 -2.84 0.04531 miRanda -0.18 0.04524 NA
111 hsa-miR-543 CD55 -0.29 0.65642 0.55 0.89013 miRanda -0.3 8.0E-5 NA
112 hsa-miR-496 CD72 0.55 0.60838 -2.48 0.10288 miRanda -0.17 0.03696 NA
113 hsa-miR-496 CDCA7 0.55 0.60838 -0.05 0.98348 miRanda -0.66 0 NA
114 hsa-miR-543 CDCA7 -0.29 0.65642 -0.05 0.98348 miRanda -0.7 0 NA
115 hsa-miR-496 CDCP1 0.55 0.60838 1.44 0.67986 miRanda -0.15 0.01447 NA
116 hsa-miR-543 CDH11 -0.29 0.65642 -1.41 0.68344 miRanda -0.28 0.0034 NA
117 hsa-miR-543 CDH17 -0.29 0.65642 1.99 0.44607 miRanda -0.46 0.00539 NA
118 hsa-miR-543 CDHR5 -0.29 0.65642 2.66 0.31323 miRanda -0.47 0.0013 NA
119 hsa-miR-375 CDK1 3.94 0.60651 0.33 0.87769 miRanda -0.22 0 NA
120 hsa-miR-496 CDK1 0.55 0.60838 0.33 0.87769 miRanda -0.27 3.0E-5 NA
121 hsa-miR-543 CDK1 -0.29 0.65642 0.33 0.87769 miRanda -0.3 2.0E-5 NA
122 hsa-miR-375 CDK2 3.94 0.60651 -0.46 0.84811 miRanda -0.12 0 NA
123 hsa-miR-496 CENPE 0.55 0.60838 0.08 0.95983 miRanda -0.21 0.00136 NA
124 hsa-miR-543 CENPE -0.29 0.65642 0.08 0.95983 miRanda -0.21 0.00363 NA
125 hsa-miR-543 CENPI -0.29 0.65642 0.31 0.67033 miRanda -0.27 0.0015 NA
126 hsa-miR-543 CENPW -0.29 0.65642 0 0.99953 miRanda -0.15 0.00956 NA
127 hsa-miR-543 CEP55 -0.29 0.65642 0.07 0.97056 miRanda -0.42 0 NA
128 hsa-miR-543 CES2 -0.29 0.65642 0.48 0.88344 miRanda -0.11 0.04098 NA
129 hsa-miR-543 CFL1 -0.29 0.65642 -0.37 0.94146 miRanda -0.12 0.00013 NA
130 hsa-miR-543 CFLAR -0.29 0.65642 -0.66 0.83109 miRanda -0.15 6.0E-5 NA
131 hsa-miR-543 CFTR -0.29 0.65642 -1.12 0.77039 miRanda -0.65 0.00222 NA
132 hsa-miR-543 CGN -0.29 0.65642 2.1 0.56692 miRanda -0.33 6.0E-5 NA
133 hsa-miR-543 CHML -0.29 0.65642 -0.35 0.86584 miRanda -0.15 0.00123 NA
134 hsa-miR-543 CHMP2B -0.29 0.65642 -0.04 0.98959 miRanda -0.12 0.00017 NA
135 hsa-miR-543 CHMP4C -0.29 0.65642 0.82 0.73264 miRanda -0.26 2.0E-5 NA
136 hsa-miR-496 CHST4 0.55 0.60838 -0.95 0.69336 miRanda -0.52 0.0004 NA
137 hsa-miR-496 CLCN1 0.55 0.60838 0.85 0.48863 miRanda -0.43 0.00135 NA
138 hsa-miR-496 CLDN1 0.55 0.60838 -0.78 0.83062 miRanda -0.27 0.00195 NA
139 hsa-miR-496 CLDN18 0.55 0.60838 0.1 0.98095 miRanda -1.06 3.0E-5 NA
140 hsa-miR-543 CLDN18 -0.29 0.65642 0.1 0.98095 miRanda -1.29 0 NA
141 hsa-miR-496 CLDN23 0.55 0.60838 -0.07 0.9754 miRanda -0.36 1.0E-5 NA
142 hsa-miR-375 CLEC2B 3.94 0.60651 -1.28 0.50089 miRanda -0.13 8.0E-5 NA
143 hsa-miR-543 CLINT1 -0.29 0.65642 -0.03 0.99402 miRanda -0.11 0.00602 NA
144 hsa-miR-543 CMPK1 -0.29 0.65642 -0.13 0.97342 miRanda -0.1 0.00241 NA
145 hsa-miR-543 CMTM1 -0.29 0.65642 0.23 0.89004 miRanda -0.14 0.01418 NA
146 hsa-miR-543 CMTM6 -0.29 0.65642 -0.27 0.94028 miRanda -0.1 0.00755 NA
147 hsa-miR-543 CNIH4 -0.29 0.65642 0.43 0.87155 miRanda -0.1 0.00047 NA
148 hsa-miR-496 COL10A1 0.55 0.60838 -1.68 0.64948 miRanda -0.46 0.00178 NA
149 hsa-miR-543 COL10A1 -0.29 0.65642 -1.68 0.64948 miRanda -0.69 1.0E-5 NA
150 hsa-miR-543 COL11A1 -0.29 0.65642 -1.22 0.73189 miRanda -0.86 2.0E-5 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 TISSUE DEVELOPMENT 136 1518 1.578e-24 7.343e-21
2 EPITHELIUM DEVELOPMENT 89 945 2.167e-17 2.556e-14
3 EMBRYO DEVELOPMENT 86 894 2.197e-17 2.556e-14
4 ORGAN MORPHOGENESIS 83 841 1.838e-17 2.556e-14
5 TISSUE MORPHOGENESIS 56 533 3.375e-13 3.14e-10
6 REGULATION OF CELL PROLIFERATION 108 1496 6.63e-13 5.142e-10
7 EMBRYONIC MORPHOGENESIS 55 539 1.801e-12 1.197e-09
8 POSITIVE REGULATION OF MOLECULAR FUNCTION 120 1791 4.492e-12 2.613e-09
9 EMBRYONIC ORGAN DEVELOPMENT 45 406 1.269e-11 6.561e-09
10 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 54 554 1.711e-11 7.962e-09
11 TUBE DEVELOPMENT 53 552 4.671e-11 1.976e-08
12 REGULATION OF STEM CELL DIFFERENTIATION 22 113 6.141e-11 2.381e-08
13 RESPONSE TO CYTOKINE 62 714 6.865e-11 2.457e-08
14 TUBE MORPHOGENESIS 38 323 9.053e-11 3.009e-08
15 REPRODUCTIVE SYSTEM DEVELOPMENT 43 408 1.851e-10 5.743e-08
16 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 22 122 2.917e-10 8.406e-08
17 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 117 1848 3.071e-10 8.406e-08
18 CYTOKINE MEDIATED SIGNALING PATHWAY 45 452 4.465e-10 1.154e-07
19 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 19 93 5.235e-10 1.282e-07
20 REGULATION OF CELLULAR COMPONENT MOVEMENT 63 771 5.747e-10 1.337e-07
21 IMMUNE SYSTEM PROCESS 122 1984 7.277e-10 1.612e-07
22 EPITHELIAL CELL DIFFERENTIATION 47 495 8.752e-10 1.851e-07
23 POSITIVE REGULATION OF CATALYTIC ACTIVITY 100 1518 9.338e-10 1.889e-07
24 MORPHOGENESIS OF AN EPITHELIUM 41 400 1.141e-09 2.212e-07
25 SKELETAL SYSTEM DEVELOPMENT 44 455 1.74e-09 3.239e-07
26 POSITIVE REGULATION OF RESPONSE TO STIMULUS 118 1929 2.004e-09 3.587e-07
27 CELL DIVISION 44 460 2.44e-09 4.204e-07
28 REGULATION OF CELL DEATH 96 1472 3.564e-09 5.923e-07
29 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 105 1672 4.595e-09 7.373e-07
30 POSITIVE REGULATION OF LOCOMOTION 41 420 4.798e-09 7.441e-07
31 GLAND DEVELOPMENT 39 395 8.356e-09 1.254e-06
32 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 91 1395 9.536e-09 1.387e-06
33 SKELETAL SYSTEM MORPHOGENESIS 26 201 1.212e-08 1.708e-06
34 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 13 50 1.302e-08 1.782e-06
35 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 69 957 1.552e-08 2.064e-06
36 STEM CELL DIFFERENTIATION 25 190 1.632e-08 2.11e-06
37 MITOTIC SISTER CHROMATID SEGREGATION 17 91 1.769e-08 2.225e-06
38 EMBRYONIC ORGAN MORPHOGENESIS 31 279 1.933e-08 2.367e-06
39 POSITIVE REGULATION OF HYDROLASE ACTIVITY 66 905 2.108e-08 2.515e-06
40 MITOTIC NUCLEAR DIVISION 36 361 2.435e-08 2.833e-06
41 POSITIVE REGULATION OF CELL COMMUNICATION 96 1532 2.599e-08 2.95e-06
42 REGULATION OF CELL DIFFERENTIATION 94 1492 2.867e-08 3.133e-06
43 LOCOMOTION 76 1114 2.895e-08 3.133e-06
44 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 77 1142 3.813e-08 4.033e-06
45 RESPONSE TO LIPID 64 888 5.415e-08 5.599e-06
46 REGULATION OF HYDROLASE ACTIVITY 85 1327 6.99e-08 6.842e-06
47 SISTER CHROMATID SEGREGATION 23 176 6.928e-08 6.842e-06
48 CELLULAR RESPONSE TO CYTOKINE STIMULUS 49 606 7.058e-08 6.842e-06
49 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 82 1275 1.029e-07 9.771e-06
50 CELL PROLIFERATION 52 672 1.14e-07 1.039e-05
51 CARDIOVASCULAR SYSTEM DEVELOPMENT 58 788 1.161e-07 1.039e-05
52 CIRCULATORY SYSTEM DEVELOPMENT 58 788 1.161e-07 1.039e-05
53 CHROMOSOME SEGREGATION 29 272 1.36e-07 1.194e-05
54 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 99 1656 1.513e-07 1.304e-05
55 ENDODERM DEVELOPMENT 14 71 1.586e-07 1.342e-05
56 ORGANELLE FISSION 42 496 1.793e-07 1.49e-05
57 RESPONSE TO OXYGEN CONTAINING COMPOUND 86 1381 1.988e-07 1.623e-05
58 GLAND MORPHOGENESIS 16 97 2.819e-07 2.262e-05
59 FORMATION OF PRIMARY GERM LAYER 17 110 3.175e-07 2.504e-05
60 REGULATION OF CYTOKINE PRODUCTION 45 563 3.382e-07 2.575e-05
61 INFLAMMATORY RESPONSE 39 454 3.431e-07 2.575e-05
62 IMMUNE RESPONSE 72 1100 3.425e-07 2.575e-05
63 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 47 602 3.649e-07 2.695e-05
64 POSITIVE REGULATION OF CELL DEATH 47 605 4.209e-07 3.06e-05
65 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 66 983 4.476e-07 3.204e-05
66 NUCLEAR CHROMOSOME SEGREGATION 25 228 5.842e-07 4.119e-05
67 DIGESTIVE TRACT MORPHOGENESIS 11 48 6.922e-07 4.807e-05
68 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 103 1805 7.574e-07 5.135e-05
69 POSITIVE REGULATION OF CELL PROLIFERATION 57 814 7.615e-07 5.135e-05
70 ENDODERM FORMATION 11 50 1.073e-06 7.131e-05
71 MESENCHYME DEVELOPMENT 22 190 1.101e-06 7.216e-05
72 RESPONSE TO EXTERNAL STIMULUS 103 1821 1.138e-06 7.353e-05
73 ACTIVATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 15 95 1.179e-06 7.518e-05
74 DIGESTIVE SYSTEM DEVELOPMENT 19 148 1.244e-06 7.822e-05
75 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 30 321 1.408e-06 8.736e-05
76 CELL DEVELOPMENT 85 1426 1.442e-06 8.828e-05
77 DEFENSE RESPONSE 76 1231 1.511e-06 8.897e-05
78 REGULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 8 25 1.502e-06 8.897e-05
79 NEGATIVE REGULATION OF CELL DEATH 59 872 1.473e-06 8.897e-05
80 ANTERIOR POSTERIOR PATTERN SPECIFICATION 22 194 1.567e-06 9.112e-05
81 VASCULATURE DEVELOPMENT 38 469 2.021e-06 0.0001161
82 ZYMOGEN ACTIVATION 16 112 2.066e-06 0.0001172
83 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 23 213 2.138e-06 0.0001198
84 POSITIVE REGULATION OF GENE EXPRESSION 98 1733 2.177e-06 0.0001205
85 REGIONALIZATION 29 311 2.202e-06 0.0001205
86 BIOLOGICAL ADHESION 66 1032 2.411e-06 0.0001304
87 PATTERN SPECIFICATION PROCESS 35 418 2.456e-06 0.0001313
88 CRANIAL SKELETAL SYSTEM DEVELOPMENT 11 55 2.926e-06 0.0001533
89 REPRODUCTION 78 1297 2.933e-06 0.0001533
90 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 65 1021 3.356e-06 0.0001735
91 EMBRYONIC CRANIAL SKELETON MORPHOGENESIS 10 46 3.727e-06 0.0001906
92 CARDIAC CHAMBER MORPHOGENESIS 15 104 3.797e-06 0.000192
93 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 64 1004 3.843e-06 0.0001922
94 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 54 801 4.627e-06 0.000229
95 ACTIN FILAMENT BASED PROCESS 36 450 4.995e-06 0.0002447
96 RESPONSE TO ENDOGENOUS STIMULUS 84 1450 5.089e-06 0.0002467
97 MESENCHYMAL CELL DIFFERENTIATION 17 134 5.268e-06 0.0002527
98 REGULATION OF CHEMOTAXIS 20 180 6.326e-06 0.0003004
99 SENSORY ORGAN DEVELOPMENT 38 493 6.517e-06 0.0003063
100 CELL DEATH 63 1001 6.887e-06 0.0003173
101 POSITIVE REGULATION OF LEUKOCYTE MIGRATION 15 109 6.862e-06 0.0003173
102 RESPONSE TO ABIOTIC STIMULUS 64 1024 7.251e-06 0.0003285
103 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 57 876 7.271e-06 0.0003285
104 CELL MOTILITY 55 835 7.436e-06 0.0003295
105 LOCALIZATION OF CELL 55 835 7.436e-06 0.0003295
106 MORPHOGENESIS OF A BRANCHING STRUCTURE 19 167 7.602e-06 0.0003337
107 ENDODERMAL CELL DIFFERENTIATION 9 40 8.472e-06 0.0003684
108 REGULATION OF IMMUNE SYSTEM PROCESS 81 1403 8.647e-06 0.0003725
109 CHROMOSOME CONDENSATION 8 31 9.076e-06 0.0003737
110 APPENDAGE DEVELOPMENT 19 169 9.041e-06 0.0003737
111 LIMB DEVELOPMENT 19 169 9.041e-06 0.0003737
112 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 79 1360 9.051e-06 0.0003737
113 RESPONSE TO OXIDATIVE STRESS 30 352 9.028e-06 0.0003737
114 POSITIVE REGULATION OF DNA REPLICATION 13 86 9.89e-06 0.0004001
115 TAXIS 36 464 9.855e-06 0.0004001
116 REGULATION OF CELL CYCLE 60 949 1.002e-05 0.0004019
117 REGULATION OF EPITHELIAL CELL PROLIFERATION 26 285 1.081e-05 0.0004234
118 HEART DEVELOPMENT 36 466 1.083e-05 0.0004234
119 OSSIFICATION 24 251 1.07e-05 0.0004234
120 EPIDERMIS DEVELOPMENT 24 253 1.223e-05 0.0004742
121 POSITIVE REGULATION OF TRANSPORT 59 936 1.302e-05 0.0005007
122 CARDIAC CHAMBER DEVELOPMENT 17 144 1.392e-05 0.0005308
123 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 47 689 1.434e-05 0.0005425
124 EPITHELIAL CELL PROLIFERATION 13 89 1.449e-05 0.0005439
125 REGULATION OF ORGAN MORPHOGENESIS 23 242 1.792e-05 0.0006669
126 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 37 498 1.939e-05 0.0007161
127 ODONTOGENESIS 14 105 1.994e-05 0.0007304
128 REGULATION OF CELL CYCLE PROCESS 40 558 2.056e-05 0.0007474
129 EPITHELIAL CELL DIFFERENTIATION INVOLVED IN PROSTATE GLAND DEVELOPMENT 5 11 2.12e-05 0.0007647
130 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 11 67 2.137e-05 0.0007647
131 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 55 867 2.159e-05 0.000767
132 REGULATION OF LEUKOCYTE MIGRATION 17 149 2.184e-05 0.0007698
133 HEART MORPHOGENESIS 21 212 2.215e-05 0.0007748
134 POSITIVE REGULATION OF CHEMOTAXIS 15 120 2.232e-05 0.0007749
135 REGULATION OF CYTOSKELETON ORGANIZATION 37 502 2.307e-05 0.000795
136 REGULATION OF DNA BINDING 13 93 2.35e-05 0.0008041
137 POSITIVE REGULATION OF CELL CYCLE PROCESS 23 247 2.485e-05 0.000844
138 RESPONSE TO WOUNDING 40 563 2.518e-05 0.0008489
139 RESPONSE TO ORGANIC CYCLIC COMPOUND 57 917 2.723e-05 0.0009116
140 REGULATION OF PEPTIDASE ACTIVITY 31 392 2.806e-05 0.000926
141 SEX DIFFERENTIATION 24 266 2.799e-05 0.000926
142 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 17 153 3.083e-05 0.00101
143 REGULATION OF CELL ADHESION 43 629 3.154e-05 0.001026
144 NEGATIVE REGULATION OF CELL DIFFERENTIATION 42 609 3.181e-05 0.001028
145 POSITIVE REGULATION OF PEPTIDASE ACTIVITY 17 154 3.354e-05 0.001076
146 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 57 926 3.578e-05 0.001136
147 REGULATION OF CELLULAR PROTEIN LOCALIZATION 39 552 3.588e-05 0.001136
148 GASTRULATION 17 155 3.645e-05 0.001146
149 RESPONSE TO BIOTIC STIMULUS 55 886 3.914e-05 0.001222
150 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 13 98 4.138e-05 0.001284
151 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 48 740 4.193e-05 0.001292
152 REGULATION OF SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM 20 205 4.288e-05 0.001313
153 BLOOD VESSEL MORPHOGENESIS 29 364 4.415e-05 0.001334
154 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 82 1492 4.417e-05 0.001334
155 MITOTIC CELL CYCLE 49 766 4.951e-05 0.001486
156 REGULATION OF CELLULAR COMPONENT BIOGENESIS 49 767 5.115e-05 0.001526
157 TUBE FORMATION 15 129 5.26e-05 0.001559
158 REGULATION OF PHOSPHORUS METABOLIC PROCESS 87 1618 5.575e-05 0.001642
159 POSITIVE REGULATION OF CELL CYCLE 27 332 5.654e-05 0.001655
160 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 25 296 5.74e-05 0.001669
161 REGULATION OF DNA REPLICATION 17 161 5.915e-05 0.00171
162 ODONTOGENESIS OF DENTIN CONTAINING TOOTH 11 75 6.302e-05 0.001799
163 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 15 131 6.291e-05 0.001799
164 CELL CHEMOTAXIS 17 162 6.396e-05 0.001815
165 REGULATION OF MITOTIC CELL CYCLE 34 468 6.529e-05 0.001841
166 CARTILAGE DEVELOPMENT 16 147 6.722e-05 0.001884
167 POSITIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 18 179 6.897e-05 0.001922
168 REGULATION OF MUSCLE TISSUE DEVELOPMENT 13 103 7.012e-05 0.001931
169 REGULATION OF MUSCLE ORGAN DEVELOPMENT 13 103 7.012e-05 0.001931
170 WOUND HEALING 34 470 7.098e-05 0.001943
171 REGULATION OF GTPASE ACTIVITY 44 673 7.285e-05 0.001982
172 MUSCLE STRUCTURE DEVELOPMENT 32 432 7.395e-05 0.002001
173 POSITIVE REGULATION OF CELL DIFFERENTIATION 51 823 7.822e-05 0.002104
174 OUTFLOW TRACT SEPTUM MORPHOGENESIS 5 14 8.408e-05 0.002249
175 RESPONSE TO TUMOR NECROSIS FACTOR 21 233 8.847e-05 0.002352
176 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 20 216 8.925e-05 0.002359
177 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 28 360 9.012e-05 0.002369
178 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 9 53 9.105e-05 0.00238
179 NEGATIVE REGULATION OF MULTI ORGANISM PROCESS 16 151 9.277e-05 0.002411
180 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 93 1784 9.459e-05 0.002445
181 REGULATION OF NIK NF KAPPAB SIGNALING 8 42 9.627e-05 0.002475
182 CELLULAR RESPONSE TO OXIDATIVE STRESS 18 184 9.852e-05 0.002519
183 RESPONSE TO ESTROGEN 20 218 0.0001013 0.002577
184 POSITIVE REGULATION OF DNA METABOLIC PROCESS 18 185 0.0001056 0.002671
185 REGULATION OF CELL DIVISION 23 272 0.0001102 0.002772
186 PLACENTA DEVELOPMENT 15 138 0.0001143 0.002858
187 POSITIVE REGULATION OF KINASE ACTIVITY 34 482 0.0001156 0.002877
188 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 9 55 0.0001227 0.00302
189 MORPHOGENESIS OF AN EPITHELIAL FOLD 5 15 0.0001225 0.00302
190 IN UTERO EMBRYONIC DEVELOPMENT 25 311 0.0001265 0.003097
191 EMBRYONIC DIGESTIVE TRACT DEVELOPMENT 7 33 0.0001293 0.003133
192 POSITIVE REGULATION OF LEUKOCYTE CHEMOTAXIS 11 81 0.0001287 0.003133
193 CARDIAC MUSCLE TISSUE DEVELOPMENT 15 140 0.0001344 0.00324
194 BODY MORPHOGENESIS 8 44 0.0001358 0.003258
195 EPITHELIAL TO MESENCHYMAL TRANSITION 9 56 0.0001416 0.003379
196 REGULATION OF PROTEIN MODIFICATION PROCESS 89 1710 0.0001433 0.003403
197 REGULATION OF LEUKOCYTE CHEMOTAXIS 12 96 0.000145 0.003426
198 POSITIVE REGULATION OF DNA TEMPLATED TRANSCRIPTION INITIATION 6 24 0.0001502 0.003529
199 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 23 278 0.0001525 0.003548
200 CELL CYCLE 72 1316 0.000152 0.003548
201 INTRACELLULAR SIGNAL TRANSDUCTION 83 1572 0.0001536 0.003555
202 ACTIN FILAMENT ORGANIZATION 17 174 0.0001548 0.003566
203 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 28 372 0.000157 0.003598
204 POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 7 34 0.0001579 0.0036
205 SPROUTING ANGIOGENESIS 8 45 0.0001601 0.003634
206 NEGATIVE REGULATION OF CELL CYCLE 31 433 0.0001759 0.003973
207 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 40 616 0.0001772 0.003983
208 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 35 514 0.0001826 0.004086
209 RESPONSE TO INTERFERON GAMMA 15 144 0.0001841 0.0041
210 LUNG CELL DIFFERENTIATION 6 25 0.0001917 0.004228
211 SKIN DEVELOPMENT 19 211 0.0001909 0.004228
212 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 20 229 0.0001974 0.004333
213 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 43 684 0.0002078 0.00454
214 RESPONSE TO ESTRADIOL 15 146 0.0002145 0.004664
215 REGULATION OF CELL DEVELOPMENT 50 836 0.0002157 0.004668
216 RESPONSE TO INORGANIC SUBSTANCE 33 479 0.000224 0.004818
217 EXTRACELLULAR STRUCTURE ORGANIZATION 24 304 0.0002247 0.004818
218 REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 7 36 0.0002303 0.004917
219 MOVEMENT IN ENVIRONMENT OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 11 87 0.0002455 0.004967
220 ENTRY INTO CELL OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 11 87 0.0002455 0.004967
221 EMBRYONIC DIGESTIVE TRACT MORPHOGENESIS 5 17 0.0002379 0.004967
222 VIRAL ENTRY INTO HOST CELL 11 87 0.0002455 0.004967
223 ENTRY INTO OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 11 87 0.0002455 0.004967
224 CHONDROCYTE DIFFERENTIATION 9 60 0.0002437 0.004967
225 FEMALE SEX DIFFERENTIATION 13 116 0.0002369 0.004967
226 TISSUE REMODELING 11 87 0.0002455 0.004967
227 MOVEMENT IN HOST ENVIRONMENT 11 87 0.0002455 0.004967
228 ENTRY INTO HOST 11 87 0.0002455 0.004967
229 RESPONSE TO ALCOHOL 27 362 0.0002366 0.004967
230 ENTRY INTO HOST CELL 11 87 0.0002455 0.004967
231 POSITIVE REGULATION OF NF KAPPAB TRANSCRIPTION FACTOR ACTIVITY 14 132 0.0002477 0.004974
232 RESPONSE TO TRANSITION METAL NANOPARTICLE 15 148 0.0002491 0.004974
233 REGULATION OF VASCULATURE DEVELOPMENT 20 233 0.0002484 0.004974
234 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 8 48 0.0002553 0.005055
235 REGULATION OF ORGANELLE ORGANIZATION 65 1178 0.0002545 0.005055
236 MAMMARY GLAND DEVELOPMENT 13 117 0.000258 0.005087
237 EYE DEVELOPMENT 25 326 0.0002617 0.005139
238 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 27 365 0.0002699 0.005277
239 REGULATION OF STEM CELL PROLIFERATION 11 88 0.0002718 0.005291
240 CHROMOSOME LOCALIZATION 9 61 0.000277 0.005326
241 DIGESTIVE SYSTEM PROCESS 9 61 0.000277 0.005326
242 NEGATIVE REGULATION OF EPITHELIAL CELL DIFFERENTIATION 7 37 0.0002755 0.005326
243 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 14 134 0.0002897 0.005547
244 POSITIVE REGULATION OF NEUTROPHIL MIGRATION 6 27 0.0003017 0.005705
245 RESPONSE TO BACTERIUM 35 528 0.0003028 0.005705
246 REGULATION OF VIRAL GENOME REPLICATION 10 75 0.0003012 0.005705
247 NEURAL CREST CELL DIFFERENTIATION 10 75 0.0003012 0.005705
248 CARDIAC VENTRICLE MORPHOGENESIS 9 62 0.000314 0.005892
249 CELL JUNCTION ORGANIZATION 17 185 0.0003219 0.006015
250 REGULATION OF ACTIN FILAMENT BASED PROCESS 24 312 0.0003296 0.006135
251 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 57 1008 0.000335 0.006211
252 MUSCLE TISSUE DEVELOPMENT 22 275 0.0003367 0.006217
253 REGULATION OF MULTI ORGANISM PROCESS 32 470 0.0003412 0.006276
254 RESPONSE TO METAL ION 25 333 0.0003603 0.006542
255 NEGATIVE REGULATION OF MOLECULAR FUNCTION 60 1079 0.0003613 0.006542
256 NEUROGENESIS 74 1402 0.0003594 0.006542
257 DEVELOPMENTAL GROWTH 25 333 0.0003603 0.006542
258 CELLULAR COMPONENT MORPHOGENESIS 52 900 0.0003698 0.00667
259 REGULATION OF KERATINOCYTE PROLIFERATION 6 28 0.0003725 0.006693
260 CELL CYCLE PROCESS 60 1081 0.0003788 0.00678
261 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 58 1036 0.0003824 0.006791
262 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 58 1036 0.0003824 0.006791
263 NEGATIVE REGULATION OF CELL ADHESION 19 223 0.0003858 0.006823
264 CYTOSKELETON DEPENDENT CYTOKINESIS 7 39 0.0003871 0.006823
265 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 63 1152 0.000401 0.007042
266 REGULATION OF BONE DEVELOPMENT 5 19 0.0004215 0.007345
267 REGULATION OF ATTACHMENT OF SPINDLE MICROTUBULES TO KINETOCHORE 4 11 0.0004211 0.007345
268 REGULATION OF PROTEIN LOCALIZATION 54 950 0.0004235 0.007353
269 RESPONSE TO STEROID HORMONE 33 497 0.0004331 0.007491
270 STRIATED MUSCLE CELL DIFFERENTIATION 16 173 0.0004445 0.007661
271 POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 6 29 0.0004558 0.007826
272 RESPONSE TO REACTIVE OXYGEN SPECIES 17 191 0.0004666 0.007982
273 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 47 799 0.0004776 0.00814
274 CELL FATE COMMITMENT 19 227 0.0004812 0.008171
275 REGULATION OF DNA METABOLIC PROCESS 25 340 0.0004903 0.008296
276 REGULATION OF CELLULAR LOCALIZATION 68 1277 0.0004932 0.008315
277 MESODERM MORPHOGENESIS 9 66 0.0005053 0.008489
278 CELLULAR RESPONSE TO MECHANICAL STIMULUS 10 80 0.0005106 0.008547
279 EPIDERMAL CELL DIFFERENTIATION 14 142 0.0005248 0.008752
280 PROSTATE GLAND DEVELOPMENT 7 41 0.0005322 0.008844
281 CONNECTIVE TISSUE DEVELOPMENT 17 194 0.0005579 0.009238
282 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 12 111 0.0005659 0.009338
283 REGENERATION 15 161 0.0006139 0.00999
284 TROPHOBLAST GIANT CELL DIFFERENTIATION 4 12 0.0006141 0.00999
285 REGULATION OF OSTEOBLAST DIFFERENTIATION 12 112 0.0006139 0.00999
286 REGULATION OF OSSIFICATION 16 178 0.0006085 0.00999
NumGOOverlapSizeP ValueAdj. P Value
1 ACTIN BINDING 33 393 4.468e-06 0.001303
2 CHEMOKINE ACTIVITY 10 48 5.61e-06 0.001303
3 CHEMOKINE RECEPTOR BINDING 11 57 4.23e-06 0.001303
4 MACROMOLECULAR COMPLEX BINDING 83 1399 2.334e-06 0.001303
5 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 28 315 8.179e-06 0.00152
6 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 44 629 1.463e-05 0.001941
7 CYTOKINE RECEPTOR BINDING 25 271 1.313e-05 0.001941
8 RECEPTOR BINDING 83 1476 1.75e-05 0.002033
9 PROTEIN DOMAIN SPECIFIC BINDING 43 624 2.614e-05 0.002698
10 PROTEIN KINASE C BINDING 9 50 5.659e-05 0.005257
11 PROTEIN COMPLEX BINDING 56 935 8.747e-05 0.007388
NumGOOverlapSizeP ValueAdj. P Value
1 MEMBRANE MICRODOMAIN 31 288 4.049e-08 1.182e-05
2 MEMBRANE REGION 77 1134 2.84e-08 1.182e-05
3 CELL SURFACE 56 757 1.642e-07 3.197e-05
4 CONDENSED CHROMOSOME OUTER KINETOCHORE 6 12 1.484e-06 0.0002166
5 ANCHORING JUNCTION 39 489 2.18e-06 0.0002546
6 CELL SUBSTRATE JUNCTION 33 398 5.842e-06 0.0005686
7 EXTRACELLULAR SPACE 80 1376 7.653e-06 0.0006385
8 APICAL PART OF CELL 30 361 1.473e-05 0.0009561
9 INTRINSIC COMPONENT OF PLASMA MEMBRANE 91 1649 1.381e-05 0.0009561
10 PLASMA MEMBRANE REGION 58 929 2.038e-05 0.001107
11 CONDENSED CHROMOSOME 20 195 2.085e-05 0.001107
12 CHROMOSOME CENTROMERIC REGION 18 174 4.754e-05 0.002314
13 ACTIN CYTOSKELETON 33 444 5.37e-05 0.002413
14 TRANSCRIPTION FACTOR COMPLEX 24 298 0.0001666 0.006949
15 PHAGOCYTIC VESICLE MEMBRANE 9 58 0.0001869 0.007277
16 CELL JUNCTION 64 1151 0.0002306 0.008417
17 MIDBODY 14 132 0.0002477 0.008508
18 EXTRACELLULAR MATRIX 30 426 0.0002947 0.009561

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 TNF_signaling_pathway_hsa04668 17 108 2.42e-07 1.259e-05
2 p53_signaling_pathway_hsa04115 13 68 6.399e-07 1.664e-05
3 Cytokine_cytokine_receptor_interaction_hsa04060 26 270 4.081e-06 7.074e-05
4 Apoptosis_hsa04210 16 138 3.1e-05 0.000403
5 Adherens_junction_hsa04520 10 72 0.0002143 0.002228
6 MAPK_signaling_pathway_hsa04010 23 295 0.0003599 0.003119
7 Necroptosis_hsa04217 14 164 0.002126 0.01579
8 Ferroptosis_hsa04216 6 40 0.002648 0.0171
9 Tight_junction_hsa04530 14 170 0.002959 0.0171
10 Apoptosis_multiple_species_hsa04215 5 33 0.005717 0.02973
11 Regulation_of_actin_cytoskeleton_hsa04810 15 208 0.007345 0.03472
12 Hippo_signaling_pathway_hsa04390 12 154 0.008745 0.03789
13 Focal_adhesion_hsa04510 14 199 0.01153 0.04324
14 Cellular_senescence_hsa04218 12 160 0.01164 0.04324
15 Ras_signaling_pathway_hsa04014 15 232 0.01852 0.05961
16 NF_kappa_B_signaling_pathway_hsa04064 8 95 0.0194 0.05961
17 Phagosome_hsa04145 11 152 0.01949 0.05961
18 ECM_receptor_interaction_hsa04512 7 82 0.02606 0.0717
19 PI3K_Akt_signaling_pathway_hsa04151 20 352 0.02622 0.0717
20 Endocytosis_hsa04144 15 244 0.02758 0.0717
21 Rap1_signaling_pathway_hsa04015 13 206 0.0321 0.07949
22 Cell_adhesion_molecules_.CAMs._hsa04514 9 145 0.07275 0.1701
23 Wnt_signaling_pathway_hsa04310 9 146 0.07524 0.1701
24 Hippo_signaling_pathway_multiple_species_hsa04392 3 29 0.08176 0.1771
25 FoxO_signaling_pathway_hsa04068 8 132 0.097 0.2018
26 Lysosome_hsa04142 7 123 0.1465 0.2929
27 Gap_junction_hsa04540 5 88 0.2013 0.3876
28 Phospholipase_D_signaling_pathway_hsa04072 7 146 0.26 0.4829
29 Cell_cycle_hsa04110 6 124 0.2761 0.4858
30 HIF_1_signaling_pathway_hsa04066 5 100 0.2803 0.4858
31 TGF_beta_signaling_pathway_hsa04350 4 84 0.3467 0.5426
32 VEGF_signaling_pathway_hsa04370 3 59 0.3477 0.5426
33 Jak_STAT_signaling_pathway_hsa04630 7 162 0.3502 0.5426
34 ErbB_signaling_pathway_hsa04012 4 85 0.3548 0.5426
35 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 6 139 0.3698 0.5494
36 cAMP_signaling_pathway_hsa04024 8 198 0.4026 0.5816
37 Calcium_signaling_pathway_hsa04020 7 182 0.466 0.652
38 ABC_transporters_hsa02010 2 45 0.4765 0.652
39 Notch_signaling_pathway_hsa04330 2 48 0.5107 0.6809
40 Peroxisome_hsa04146 3 83 0.5671 0.7373
41 Sphingolipid_signaling_pathway_hsa04071 4 118 0.605 0.7673
42 Oocyte_meiosis_hsa04114 4 124 0.6439 0.7958
43 Autophagy_animal_hsa04140 4 128 0.6684 0.7958
44 Mitophagy_animal_hsa04137 2 65 0.6753 0.7958
45 cGMP_PKG_signaling_pathway_hsa04022 5 163 0.6886 0.7958
46 mTOR_signaling_pathway_hsa04150 4 151 0.7863 0.8846
47 AMPK_signaling_pathway_hsa04152 3 121 0.8066 0.8846
48 Neuroactive_ligand_receptor_interaction_hsa04080 7 278 0.8659 0.9047
49 Phosphatidylinositol_signaling_system_hsa04070 2 99 0.8699 0.9047
50 Apelin_signaling_pathway_hsa04371 2 137 0.9573 0.976

Quest ID: 831513eeaf3963c9c88b9b3facf9ad1a