Visible node/edge number:
Node colors:
Node labels:

show label of nodes with degree >=

Node sizes:
Edge colors:
Edge widths factor:
Layout:

gravity >=

edgeLength =

GRN in network:

Notice: IE browser need to manually refresh (F5) this page after resetting the network.

This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-140-3p ADAM17 -0.97 0 0.52 0.0008 PITA; miRNATAP -0.19 0.00477 NA
2 hsa-miR-338-3p ADAM17 -0.95 0 0.52 0.0008 PITA; miRanda; miRNATAP -0.27 0 26617808 MiR 338 3p inhibits the proliferation and migration of gastric cancer cells by targeting ADAM17; Moreover we identified A disintegrin and metalloproteinase 17 ADAM17 gene as potential target of miR-338-3p; Importantly ADAM17 rescued the miR-338-3p mediated inhibition of cell proliferation migration and invasion; Our study suggested that miR-338-3p is significantly decreased in gastric cancer and inhibits cell proliferation migration and invasion partially via the downregulation of ADAM17
3 hsa-let-7a-3p CREBBP 0.1 0.42376 0.02 0.83362 miRNATAP -0.14 9.0E-5 NA
4 hsa-miR-186-5p CREBBP 0.35 0.00015 0.02 0.83362 mirMAP; miRNATAP -0.27 0 NA
5 hsa-miR-26b-5p CREBBP -0.25 0.02852 0.02 0.83362 miRNATAP -0.21 0 NA
6 hsa-miR-30d-3p CREBBP -0.58 0 0.02 0.83362 MirTarget; miRNATAP -0.13 0.00047 NA
7 hsa-miR-590-3p CREBBP 0.22 0.09659 0.02 0.83362 PITA; miRanda; mirMAP; miRNATAP -0.1 0.00208 NA
8 hsa-miR-130b-3p DLL1 1.45 0 -0.24 0.18824 miRNATAP -0.18 0.00056 NA
9 hsa-miR-149-5p DLL1 0.44 0.0642 -0.24 0.18824 miRNATAP -0.18 0 NA
10 hsa-miR-320a DLL1 0.8 0 -0.24 0.18824 miRanda -0.16 0.00522 NA
11 hsa-miR-320b DLL1 1.23 0 -0.24 0.18824 miRanda -0.21 1.0E-5 NA
12 hsa-miR-34a-5p DLL1 -0.12 0.364 -0.24 0.18824 miRNAWalker2 validate; miRTarBase; miRNATAP -0.32 0 22438124 Delta tocotrienol suppresses Notch 1 pathway by upregulating miR 34a in nonsmall cell lung cancer cells
13 hsa-miR-362-5p DLL1 0.41 0.04043 -0.24 0.18824 PITA; TargetScan; miRNATAP -0.16 3.0E-5 NA
14 hsa-miR-423-3p DLL1 1.2 0 -0.24 0.18824 PITA -0.17 0.00848 NA
15 hsa-miR-429 DLL1 0.56 0.00564 -0.24 0.18824 miRanda; miRNATAP -0.16 6.0E-5 NA
16 hsa-let-7a-3p DLL4 0.1 0.42376 0.92 0 miRNATAP -0.3 0 NA
17 hsa-miR-15a-5p DLL4 0.78 0 0.92 0 miRNATAP -0.16 0.00161 NA
18 hsa-miR-16-5p DLL4 0.52 0 0.92 0 miRNATAP -0.17 0.00283 NA
19 hsa-miR-27b-3p DLL4 -0.73 0 0.92 0 miRNATAP -0.21 1.0E-5 NA
20 hsa-miR-29a-5p DLL4 0.32 0.03704 0.92 0 miRNATAP -0.15 0.00017 NA
21 hsa-miR-30c-5p DLL4 0.02 0.88637 0.92 0 miRNATAP -0.17 2.0E-5 NA
22 hsa-miR-429 DLL4 0.56 0.00564 0.92 0 miRanda -0.21 0 NA
23 hsa-miR-324-5p DTX1 1.67 0 -0.6 0.00015 PITA; miRanda -0.17 1.0E-5 NA
24 hsa-miR-331-3p DTX1 0.91 0 -0.6 0.00015 PITA; miRNATAP -0.16 0.00107 NA
25 hsa-miR-421 DTX1 0.95 0 -0.6 0.00015 PITA; miRanda; miRNATAP -0.12 0.00439 NA
26 hsa-miR-429 DTX1 0.56 0.00564 -0.6 0.00015 miRNATAP -0.18 0 NA
27 hsa-let-7b-5p DTX2 -0.25 0.02114 0.02 0.83612 miRNATAP -0.16 0.00062 NA
28 hsa-let-7e-5p DTX2 0.09 0.51287 0.02 0.83612 miRNATAP -0.18 0 NA
29 hsa-miR-495-3p DTX2 -1.48 0 0.02 0.83612 mirMAP -0.15 0 NA
30 hsa-miR-139-5p DTX3 -1.46 0 0.6 0.00022 PITA; miRanda; miRNATAP -0.21 0 NA
31 hsa-miR-3614-5p DTX3 0.96 3.0E-5 0.6 0.00022 MirTarget -0.15 0 NA
32 hsa-miR-182-5p DTX3L 1.15 0 0.87 0 mirMAP -0.12 3.0E-5 NA
33 hsa-miR-340-3p DTX3L 0.29 0.03713 0.87 0 MirTarget -0.11 0.0059 NA
34 hsa-miR-493-5p DTX3L -0.47 0.02213 0.87 0 MirTarget -0.13 0 NA
35 hsa-miR-495-3p DTX3L -1.48 0 0.87 0 mirMAP -0.15 0 NA
36 hsa-miR-27a-3p DTX4 0.35 0.00127 -0.11 0.50742 miRNATAP -0.18 0.00905 NA
37 hsa-miR-107 DVL1 -0.04 0.67162 -0.32 0.00336 PITA; miRanda -0.35 0 NA
38 hsa-miR-378a-3p DVL1 -1.5 0 -0.32 0.00336 miRNAWalker2 validate -0.1 4.0E-5 NA
39 hsa-miR-744-5p DVL1 0.44 0.00085 -0.32 0.00336 miRNAWalker2 validate -0.11 0.00226 NA
40 hsa-miR-125a-5p DVL3 0.22 0.11955 0.76 0 PITA -0.12 0.00045 NA
41 hsa-miR-146b-3p DVL3 0.19 0.16914 0.76 0 MirTarget -0.11 0.0021 NA
42 hsa-miR-26b-5p DVL3 -0.25 0.02852 0.76 0 miRNAWalker2 validate -0.21 0 NA
43 hsa-miR-29b-2-5p DVL3 -0.5 0.00073 0.76 0 MirTarget -0.11 0.00078 NA
44 hsa-miR-30d-3p DVL3 -0.58 0 0.76 0 MirTarget -0.14 0.0003 NA
45 hsa-miR-338-3p DVL3 -0.95 0 0.76 0 miRanda -0.2 0 NA
46 hsa-miR-140-5p EP300 -0.41 0.00014 -0.04 0.77828 miRNAWalker2 validate -0.14 0.00917 NA
47 hsa-miR-181b-5p EP300 0.97 0 -0.04 0.77828 miRNAWalker2 validate -0.25 0 NA
48 hsa-miR-182-5p EP300 1.15 0 -0.04 0.77828 miRNAWalker2 validate; miRNATAP -0.11 0.00038 NA
49 hsa-miR-186-5p EP300 0.35 0.00015 -0.04 0.77828 miRNATAP -0.39 0 NA
50 hsa-miR-193b-3p EP300 1.73 0 -0.04 0.77828 miRNAWalker2 validate -0.14 0 NA
51 hsa-miR-20a-5p EP300 1.15 0 -0.04 0.77828 miRNATAP -0.26 0 NA
52 hsa-miR-2355-3p EP300 1.58 0 -0.04 0.77828 MirTarget; miRNATAP -0.13 2.0E-5 NA
53 hsa-miR-25-3p EP300 0.77 0 -0.04 0.77828 miRNAWalker2 validate -0.17 0.00053 NA
54 hsa-miR-26b-5p EP300 -0.25 0.02852 -0.04 0.77828 miRNAWalker2 validate; miRNATAP -0.32 0 NA
55 hsa-miR-29b-1-5p EP300 1.4 0 -0.04 0.77828 MirTarget -0.18 0 NA
56 hsa-miR-30c-5p EP300 0.02 0.88637 -0.04 0.77828 miRNAWalker2 validate -0.35 0 NA
57 hsa-miR-30d-3p EP300 -0.58 0 -0.04 0.77828 MirTarget; miRNATAP -0.18 0.00016 NA
58 hsa-miR-339-5p EP300 1.08 0 -0.04 0.77828 miRanda -0.25 0 NA
59 hsa-miR-342-3p EP300 1 0 -0.04 0.77828 MirTarget; PITA; miRanda; miRNATAP -0.28 0 NA
60 hsa-miR-361-3p EP300 0.27 0.01479 -0.04 0.77828 PITA -0.22 3.0E-5 NA
61 hsa-miR-374b-5p EP300 -0.29 0.00415 -0.04 0.77828 mirMAP; miRNATAP -0.29 0 NA
62 hsa-miR-582-3p EP300 -0.25 0.1438 -0.04 0.77828 MirTarget; PITA -0.11 0.00136 NA
63 hsa-miR-590-3p EP300 0.22 0.09659 -0.04 0.77828 MirTarget; PITA; miRanda; mirMAP; miRNATAP -0.12 0.00472 NA
64 hsa-miR-92a-3p EP300 0.99 0 -0.04 0.77828 miRNAWalker2 validate -0.19 5.0E-5 NA
65 hsa-miR-96-5p EP300 1.42 0 -0.04 0.77828 TargetScan; miRNATAP -0.12 8.0E-5 NA
66 hsa-miR-23a-3p HES1 0.35 6.0E-5 -0.46 0.00014 miRNAWalker2 validate; miRTarBase -0.16 0.00729 NA
67 hsa-miR-126-5p JAG1 -0.95 0 0.99 0 MirTarget; mirMAP -0.14 0.00868 NA
68 hsa-miR-140-3p JAG1 -0.97 0 0.99 0 MirTarget; PITA; miRNATAP -0.32 0 NA
69 hsa-miR-140-5p JAG1 -0.41 0.00014 0.99 0 MirTarget; PITA; miRanda; miRNATAP -0.23 0.00021 NA
70 hsa-miR-186-5p JAG1 0.35 0.00015 0.99 0 MirTarget; miRNATAP -0.22 0.00209 NA
71 hsa-miR-200a-3p JAG1 0.61 0.0029 0.99 0 miRNATAP -0.13 4.0E-5 NA
72 hsa-miR-217 JAG1 -1.35 0 0.99 0 PITA; miRanda -0.13 1.0E-5 NA
73 hsa-miR-26a-5p JAG1 -1.09 0 0.99 0 MirTarget; miRNATAP -0.2 0.00044 NA
74 hsa-miR-26b-5p JAG1 -0.25 0.02852 0.99 0 MirTarget; miRNATAP -0.27 0 NA
75 hsa-miR-335-3p JAG1 0.34 0.05424 0.99 0 MirTarget -0.13 0.001 NA
76 hsa-miR-335-5p JAG1 -1.17 0 0.99 0 miRNATAP -0.17 0 NA
77 hsa-miR-34a-5p JAG1 -0.12 0.364 0.99 0 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.32 0 NA
78 hsa-miR-361-3p JAG1 0.27 0.01479 0.99 0 miRNATAP -0.2 0.00081 NA
79 hsa-miR-429 JAG1 0.56 0.00564 0.99 0 miRanda -0.11 0.00086 NA
80 hsa-miR-598-3p JAG1 -0.5 0.00274 0.99 0 MirTarget -0.19 0 NA
81 hsa-miR-628-5p JAG1 -0.55 5.0E-5 0.99 0 MirTarget; PITA; miRNATAP -0.26 0 NA
82 hsa-miR-140-3p JAG2 -0.97 0 0.83 0 miRNATAP -0.37 0 NA
83 hsa-miR-140-5p JAG2 -0.41 0.00014 0.83 0 miRanda -0.14 0.00949 NA
84 hsa-miR-30d-5p JAG2 -0.38 0.00017 0.83 0 miRNATAP -0.16 0.00574 NA
85 hsa-miR-502-3p JAG2 -0.17 0.10688 0.83 0 miRNATAP -0.16 0.00819 NA
86 hsa-miR-106b-5p KAT2B 0.5 1.0E-5 -2.05 0 miRNAWalker2 validate; miRTarBase; MirTarget -0.49 0 NA
87 hsa-miR-17-5p KAT2B 1.42 0 -2.05 0 MirTarget; TargetScan -0.45 0 23095762 miR 17 5p targets the p300/CBP associated factor and modulates androgen receptor transcriptional activity in cultured prostate cancer cells; Targeting of PCAF by miR-17-5p was evaluated using the luciferase reporter assay; Expression of PCAF in PCa cells was associated with the downregulation of miR-17-5p; Targeting of the 3'-untranslated region of PCAF mRNA by miR-17-5p caused translational suppression and RNA degradation and consequently modulation of AR transcriptional activity in PCa cells; PCAF is upregulated in cultured PCa cells and upregulation of PCAF is associated with the downregulation of miR-17-5p; Targeting of PCAF by miR-17-5p modulates AR transcriptional activity and cell growth in cultured PCa cells
88 hsa-miR-181a-5p KAT2B 0.82 0 -2.05 0 miRNAWalker2 validate; miRTarBase; MirTarget -0.3 1.0E-5 NA
89 hsa-miR-181b-5p KAT2B 0.97 0 -2.05 0 miRNAWalker2 validate; miRTarBase; MirTarget -0.47 0 NA
90 hsa-miR-181d-5p KAT2B 0.37 0.00537 -2.05 0 MirTarget -0.29 0 NA
91 hsa-miR-19a-3p KAT2B 1.36 0 -2.05 0 miRNAWalker2 validate -0.29 0 NA
92 hsa-miR-19b-3p KAT2B 0.54 0.00062 -2.05 0 miRNAWalker2 validate -0.28 0 NA
93 hsa-miR-205-5p KAT2B 1.51 0 -2.05 0 MirTarget -0.3 0 NA
94 hsa-miR-20a-3p KAT2B 1.35 0 -2.05 0 MirTarget -0.33 0 NA
95 hsa-miR-20a-5p KAT2B 1.15 0 -2.05 0 MirTarget -0.38 0 NA
96 hsa-miR-25-3p KAT2B 0.77 0 -2.05 0 miRNAWalker2 validate; miRTarBase; MirTarget -0.51 0 NA
97 hsa-miR-29a-5p KAT2B 0.32 0.03704 -2.05 0 MirTarget -0.13 0.00681 NA
98 hsa-miR-361-5p KAT2B 0.08 0.31404 -2.05 0 miRanda -0.43 1.0E-5 NA
99 hsa-miR-429 KAT2B 0.56 0.00564 -2.05 0 miRanda -0.27 0 NA
100 hsa-miR-450b-5p KAT2B 1.26 0 -2.05 0 MirTarget; miRNATAP -0.28 0 NA
101 hsa-miR-542-3p KAT2B 0.64 0 -2.05 0 miRanda -0.27 0 NA
102 hsa-miR-576-5p KAT2B 0.94 0 -2.05 0 mirMAP -0.29 0 NA
103 hsa-miR-590-5p KAT2B 0.76 0 -2.05 0 miRanda -0.32 0 NA
104 hsa-miR-92a-3p KAT2B 0.99 0 -2.05 0 miRNAWalker2 validate; MirTarget -0.59 0 NA
105 hsa-miR-92b-3p KAT2B 0.87 0 -2.05 0 MirTarget -0.37 0 NA
106 hsa-miR-93-5p KAT2B 1.61 0 -2.05 0 miRNAWalker2 validate; miRTarBase; MirTarget -0.46 0 NA
107 hsa-miR-944 KAT2B 1.47 0 -2.05 0 MirTarget -0.22 0 NA
108 hsa-miR-30b-5p MAML1 -0.4 0.00347 0.22 0.01002 MirTarget -0.11 5.0E-5 NA
109 hsa-miR-30c-5p MAML1 0.02 0.88637 0.22 0.01002 MirTarget; miRNATAP -0.13 0 NA
110 hsa-miR-324-5p MAML2 1.67 0 -0.77 0.00014 miRanda -0.29 0 NA
111 hsa-miR-429 MAML2 0.56 0.00564 -0.77 0.00014 miRanda -0.15 0.00061 NA
112 hsa-miR-576-5p MAML2 0.94 0 -0.77 0.00014 mirMAP -0.5 0 NA
113 hsa-miR-590-3p MAML2 0.22 0.09659 -0.77 0.00014 mirMAP -0.22 0.00095 NA
114 hsa-miR-664a-3p MAML2 -0.26 0.05132 -0.77 0.00014 mirMAP -0.23 0.00075 NA
115 hsa-miR-330-5p MAML3 0.94 0 -1.93 0 miRanda -0.27 1.0E-5 NA
116 hsa-miR-339-5p MAML3 1.08 0 -1.93 0 miRanda -0.36 0 NA
117 hsa-miR-421 MAML3 0.95 0 -1.93 0 miRanda -0.19 0.00016 NA
118 hsa-miR-429 MAML3 0.56 0.00564 -1.93 0 miRanda -0.14 0.00053 NA
119 hsa-miR-542-3p MAML3 0.64 0 -1.93 0 miRanda -0.27 1.0E-5 NA
120 hsa-miR-590-3p MAML3 0.22 0.09659 -1.93 0 miRanda -0.25 5.0E-5 NA
121 hsa-miR-205-5p MFNG 1.51 0 0.04 0.82795 MirTarget -0.2 0 NA
122 hsa-miR-2355-5p MFNG 1.47 0 0.04 0.82795 MirTarget -0.16 0.00029 NA
123 hsa-miR-10b-5p NCOR2 -0.58 0 0.11 0.22569 miRNAWalker2 validate; MirTarget; miRNATAP -0.2 0 NA
124 hsa-miR-16-5p NCOR2 0.52 0 0.11 0.22569 miRNAWalker2 validate; miRTarBase -0.12 0.00137 NA
125 hsa-miR-200b-3p NCOR2 0.07 0.68286 0.11 0.22569 TargetScan -0.11 0 NA
126 hsa-miR-20a-5p NCOR2 1.15 0 0.11 0.22569 miRNAWalker2 validate -0.16 0 NA
127 hsa-miR-29b-3p NCOR2 -0.11 0.51126 0.11 0.22569 miRNATAP -0.2 0 NA
128 hsa-miR-30c-5p NCOR2 0.02 0.88637 0.11 0.22569 miRNATAP -0.16 0 NA
129 hsa-miR-339-5p NCOR2 1.08 0 0.11 0.22569 miRanda -0.14 0 NA
130 hsa-miR-34a-5p NCOR2 -0.12 0.364 0.11 0.22569 MirTarget -0.17 0 NA
131 hsa-miR-429 NCOR2 0.56 0.00564 0.11 0.22569 PITA; miRanda; miRNATAP -0.12 0 NA
132 hsa-miR-18a-3p NOTCH1 1.83 0 -0.1 0.54477 MirTarget -0.11 0.00052 NA
133 hsa-miR-199b-5p NOTCH1 -1.08 0 -0.1 0.54477 miRanda -0.11 0.00583 24659709 Epigenetic silencing of microRNA 199b 5p is associated with acquired chemoresistance via activation of JAG1 Notch1 signaling in ovarian cancer; Here we report that the loss of miR-199b-5p due to progressive epigenetic silencing leads to the activation of the JAG1-mediated Notch1 signaling cascade thereby leading to the development of acquired chemoresistance in ovarian cancer
134 hsa-miR-2355-5p NOTCH1 1.47 0 -0.1 0.54477 MirTarget -0.23 0 NA
135 hsa-miR-30b-5p NOTCH1 -0.4 0.00347 -0.1 0.54477 miRNATAP -0.13 0.0097 NA
136 hsa-miR-30c-5p NOTCH1 0.02 0.88637 -0.1 0.54477 miRNATAP -0.16 0.00065 23974200 We identified NOTCH1 as a direct target of miR-30c; Finally a block of miR-30c prevents C/EBPα-induced downregulation of Notch1 protein and leads to a reduced CD11b expression in myeloid differentiation; Our study presents the first evidence that C/EBPα miR-30c and Notch1 together play a critical role in granulocytic differentiation and AML and particularly in AML with CEBPA mutations
137 hsa-miR-103a-3p NOTCH2 0.56 0 -0.47 0.00039 MirTarget -0.3 0 NA
138 hsa-miR-125a-5p NOTCH2 0.22 0.11955 -0.47 0.00039 miRanda -0.29 0 NA
139 hsa-miR-130b-5p NOTCH2 1.77 0 -0.47 0.00039 miRNAWalker2 validate; MirTarget -0.21 0 NA
140 hsa-miR-146b-5p NOTCH2 0.92 0 -0.47 0.00039 miRanda -0.13 0.00041 NA
141 hsa-miR-15a-5p NOTCH2 0.78 0 -0.47 0.00039 MirTarget -0.41 0 NA
142 hsa-miR-15b-5p NOTCH2 0.85 0 -0.47 0.00039 MirTarget -0.15 0.00092 NA
143 hsa-miR-16-1-3p NOTCH2 0.96 0 -0.47 0.00039 mirMAP -0.18 0 NA
144 hsa-miR-16-5p NOTCH2 0.52 0 -0.47 0.00039 miRNAWalker2 validate; MirTarget -0.18 0.00082 NA
145 hsa-miR-17-5p NOTCH2 1.42 0 -0.47 0.00039 miRNAWalker2 validate -0.28 0 NA
146 hsa-miR-181a-5p NOTCH2 0.82 0 -0.47 0.00039 miRNAWalker2 validate; MirTarget; mirMAP -0.16 0.00141 NA
147 hsa-miR-181b-5p NOTCH2 0.97 0 -0.47 0.00039 MirTarget; mirMAP -0.19 4.0E-5 NA
148 hsa-miR-181d-5p NOTCH2 0.37 0.00537 -0.47 0.00039 MirTarget -0.16 0.00026 NA
149 hsa-miR-183-5p NOTCH2 1.43 0 -0.47 0.00039 miRNAWalker2 validate -0.14 0 NA
150 hsa-miR-186-5p NOTCH2 0.35 0.00015 -0.47 0.00039 mirMAP -0.24 0.00015 NA
NumGOOverlapSizeP ValueAdj. P Value
1 NOTCH SIGNALING PATHWAY 23 114 4.484e-47 2.087e-43
2 NOTCH RECEPTOR PROCESSING 9 16 1.154e-22 2.686e-19
3 REGULATION OF NOTCH SIGNALING PATHWAY 9 67 4.111e-16 6.377e-13
4 TRANSCRIPTION INITIATION FROM RNA POLYMERASE II PROMOTER 10 153 1.343e-14 1.563e-11
5 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 15 750 3.264e-14 3.038e-11
6 POSITIVE REGULATION OF NOTCH SIGNALING PATHWAY 7 34 4.201e-14 3.258e-11
7 DNA TEMPLATED TRANSCRIPTION INITIATION 10 202 2.226e-13 1.48e-10
8 CELL FATE COMMITMENT 10 227 7.166e-13 4.168e-10
9 POSITIVE REGULATION OF GENE EXPRESSION 18 1733 2.189e-12 1.132e-09
10 REGULATION OF CELL DEVELOPMENT 14 836 3.482e-12 1.62e-09
11 MORPHOGENESIS OF AN EPITHELIUM 11 400 6.939e-12 2.935e-09
12 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 13 724 1.118e-11 4.335e-09
13 CARDIOVASCULAR SYSTEM DEVELOPMENT 13 788 3.22e-11 1.07e-08
14 CIRCULATORY SYSTEM DEVELOPMENT 13 788 3.22e-11 1.07e-08
15 HEART DEVELOPMENT 11 466 3.581e-11 1.111e-08
16 REGULATION OF CELL DIFFERENTIATION 16 1492 4.535e-11 1.319e-08
17 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 17 1805 6.214e-11 1.701e-08
18 TISSUE MORPHOGENESIS 11 533 1.501e-10 3.881e-08
19 REGULATION OF NEURON DIFFERENTIATION 11 554 2.263e-10 5.265e-08
20 TUBE DEVELOPMENT 11 552 2.178e-10 5.265e-08
21 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 16 1672 2.491e-10 5.418e-08
22 NEUROGENESIS 15 1402 2.562e-10 5.418e-08
23 EPITHELIUM DEVELOPMENT 13 945 3.054e-10 6.179e-08
24 IMMUNE SYSTEM DEVELOPMENT 11 582 3.815e-10 7.396e-08
25 HEART MORPHOGENESIS 8 212 6.689e-10 1.112e-07
26 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 13 1004 6.425e-10 1.112e-07
27 NEURON FATE COMMITMENT 6 67 6.265e-10 1.112e-07
28 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 16 1784 6.519e-10 1.112e-07
29 TISSUE DEVELOPMENT 15 1518 7.781e-10 1.248e-07
30 CARDIAC CHAMBER DEVELOPMENT 7 144 1.535e-09 2.381e-07
31 CARDIAC SEPTUM DEVELOPMENT 6 85 2.695e-09 4.045e-07
32 MORPHOGENESIS OF AN EPITHELIAL SHEET 5 43 4.947e-09 6.975e-07
33 CELL FATE DETERMINATION 5 43 4.947e-09 6.975e-07
34 EPITHELIAL CELL FATE COMMITMENT 4 15 5.549e-09 7.594e-07
35 CELL SURFACE RECEPTOR SIGNALING PATHWAY INVOLVED IN HEART DEVELOPMENT 4 16 7.391e-09 9.826e-07
36 LEUKOCYTE DIFFERENTIATION 8 292 8.309e-09 1.074e-06
37 CARDIAC CHAMBER MORPHOGENESIS 6 104 9.169e-09 1.153e-06
38 POSITIVE REGULATION OF CELL COMMUNICATION 14 1532 1.019e-08 1.186e-06
39 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 9 437 9.959e-09 1.186e-06
40 CARDIAC SEPTUM MORPHOGENESIS 5 49 9.738e-09 1.186e-06
41 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 7 191 1.097e-08 1.245e-06
42 ARTERY MORPHOGENESIS 5 51 1.197e-08 1.326e-06
43 EAR DEVELOPMENT 7 195 1.266e-08 1.37e-06
44 POSITIVE REGULATION OF CELL DIFFERENTIATION 11 823 1.429e-08 1.511e-06
45 NEURONAL STEM CELL POPULATION MAINTENANCE 4 19 1.569e-08 1.622e-06
46 ORGAN MORPHOGENESIS 11 841 1.786e-08 1.805e-06
47 TUBE MORPHOGENESIS 8 323 1.823e-08 1.805e-06
48 POSITIVE REGULATION OF CELL DEVELOPMENT 9 472 1.938e-08 1.879e-06
49 LYMPHOCYTE DIFFERENTIATION 7 209 2.043e-08 1.94e-06
50 POSITIVE REGULATION OF RESPONSE TO STIMULUS 15 1929 2.102e-08 1.956e-06
51 NEURON DIFFERENTIATION 11 874 2.655e-08 2.422e-06
52 LYMPHOCYTE ACTIVATION 8 342 2.841e-08 2.542e-06
53 EMBRYO DEVELOPMENT 11 894 3.349e-08 2.94e-06
54 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 13 1395 3.413e-08 2.941e-06
55 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 12 1142 3.758e-08 3.179e-06
56 EMBRYONIC MORPHOGENESIS 9 539 6.059e-08 5.035e-06
57 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 11 957 6.718e-08 5.484e-06
58 AUDITORY RECEPTOR CELL DIFFERENTIATION 4 28 8.212e-08 6.588e-06
59 ARTERY DEVELOPMENT 5 75 8.578e-08 6.765e-06
60 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 7 262 9.617e-08 7.458e-06
61 LEUKOCYTE ACTIVATION 8 414 1.237e-07 9.438e-06
62 PATTERN SPECIFICATION PROCESS 8 418 1.332e-07 9.995e-06
63 B CELL DIFFERENTIATION 5 89 2.033e-07 1.502e-05
64 HAIR CELL DIFFERENTIATION 4 35 2.085e-07 1.516e-05
65 ENDOTHELIUM DEVELOPMENT 5 90 2.15e-07 1.539e-05
66 NEGATIVE REGULATION OF CELL DEVELOPMENT 7 303 2.581e-07 1.819e-05
67 NEGATIVE REGULATION OF EPITHELIAL CELL DIFFERENTIATION 4 37 2.624e-07 1.822e-05
68 VASCULATURE DEVELOPMENT 8 469 3.204e-07 2.192e-05
69 CELL DEVELOPMENT 12 1426 4.258e-07 2.872e-05
70 SENSORY ORGAN DEVELOPMENT 8 493 4.677e-07 3.109e-05
71 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 5 111 6.135e-07 4.021e-05
72 REGULATION OF TIMING OF CELL DIFFERENTIATION 3 12 6.639e-07 4.232e-05
73 REGULATION OF DEVELOPMENT HETEROCHRONIC 3 12 6.639e-07 4.232e-05
74 REGULATION OF EMBRYONIC DEVELOPMENT 5 114 7.005e-07 4.405e-05
75 NEPHRON DEVELOPMENT 5 115 7.316e-07 4.539e-05
76 GLOMERULUS DEVELOPMENT 4 49 8.314e-07 5.09e-05
77 NEGATIVE REGULATION OF EPIDERMAL CELL DIFFERENTIATION 3 13 8.622e-07 5.143e-05
78 MATURE B CELL DIFFERENTIATION INVOLVED IN IMMUNE RESPONSE 3 13 8.622e-07 5.143e-05
79 BLOOD VESSEL MORPHOGENESIS 7 364 8.863e-07 5.155e-05
80 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 9 740 8.805e-07 5.155e-05
81 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 5 122 9.809e-07 5.566e-05
82 MECHANORECEPTOR DIFFERENTIATION 4 51 9.785e-07 5.566e-05
83 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 8 554 1.126e-06 6.314e-05
84 N TERMINAL PROTEIN AMINO ACID ACETYLATION 3 15 1.369e-06 7.407e-05
85 CELL ACTIVATION 8 568 1.358e-06 7.407e-05
86 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 10 1021 1.356e-06 7.407e-05
87 B CELL ACTIVATION 5 132 1.449e-06 7.659e-05
88 MAINTENANCE OF CELL NUMBER 5 132 1.449e-06 7.659e-05
89 NEGATIVE REGULATION OF EPIDERMIS DEVELOPMENT 3 16 1.683e-06 8.784e-05
90 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 9 801 1.699e-06 8.784e-05
91 IMMUNE SYSTEM PROCESS 13 1984 2.049e-06 0.0001036
92 MATURE B CELL DIFFERENTIATION 3 17 2.042e-06 0.0001036
93 EMBRYONIC HEART TUBE MORPHOGENESIS 4 62 2.159e-06 0.000108
94 NEUROEPITHELIAL CELL DIFFERENTIATION 4 63 2.303e-06 0.0001128
95 NEGATIVE REGULATION OF CELL DIFFERENTIATION 8 609 2.284e-06 0.0001128
96 NEURAL TUBE DEVELOPMENT 5 149 2.631e-06 0.0001275
97 MUSCLE STRUCTURE DEVELOPMENT 7 432 2.768e-06 0.0001328
98 KIDNEY VASCULATURE DEVELOPMENT 3 19 2.904e-06 0.0001365
99 RENAL SYSTEM VASCULATURE DEVELOPMENT 3 19 2.904e-06 0.0001365
100 EMBRYONIC ORGAN MORPHOGENESIS 6 279 3.13e-06 0.0001456
101 REGULATION OF BINDING 6 283 3.397e-06 0.0001565
102 ENDOTHELIAL CELL DIFFERENTIATION 4 72 3.941e-06 0.0001798
103 EMBRYONIC HEART TUBE DEVELOPMENT 4 73 4.165e-06 0.0001864
104 ANGIOGENESIS 6 293 4.149e-06 0.0001864
105 MEMBRANE PROTEIN ECTODOMAIN PROTEOLYSIS 3 22 4.601e-06 0.0002001
106 SOMATIC STEM CELL DIVISION 3 22 4.601e-06 0.0002001
107 AORTA MORPHOGENESIS 3 22 4.601e-06 0.0002001
108 RENAL TUBULE DEVELOPMENT 4 78 5.431e-06 0.000234
109 REGIONALIZATION 6 311 5.841e-06 0.0002493
110 EPITHELIAL CELL DIFFERENTIATION 7 495 6.774e-06 0.0002865
111 N TERMINAL PROTEIN AMINO ACID MODIFICATION 3 26 7.736e-06 0.0003243
112 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 7 513 8.552e-06 0.0003553
113 ANTERIOR POSTERIOR PATTERN SPECIFICATION 5 194 9.543e-06 0.0003929
114 REGULATION OF SPROUTING ANGIOGENESIS 3 28 9.727e-06 0.000397
115 STEM CELL DIVISION 3 29 1.084e-05 0.0004386
116 NEPHRON EPITHELIUM DEVELOPMENT 4 93 1.094e-05 0.000439
117 CARDIOCYTE DIFFERENTIATION 4 96 1.241e-05 0.0004936
118 FOREBRAIN DEVELOPMENT 6 357 1.282e-05 0.0005056
119 CARDIAC ATRIUM DEVELOPMENT 3 31 1.331e-05 0.0005203
120 LYMPHOCYTE ACTIVATION INVOLVED IN IMMUNE RESPONSE 4 98 1.347e-05 0.0005223
121 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO HYPOXIA 3 32 1.467e-05 0.0005594
122 POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 4 100 1.459e-05 0.0005594
123 HEART VALVE DEVELOPMENT 3 34 1.766e-05 0.0006681
124 CARDIAC VENTRICLE DEVELOPMENT 4 106 1.837e-05 0.0006893
125 MEMBRANE PROTEIN PROTEOLYSIS 3 35 1.93e-05 0.0007126
126 B CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE 3 35 1.93e-05 0.0007126
127 CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 3 36 2.103e-05 0.0007705
128 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 5 229 2.125e-05 0.0007726
129 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 5 232 2.262e-05 0.0008161
130 MYOBLAST DIFFERENTIATION 3 37 2.286e-05 0.0008183
131 POSITIVE REGULATION OF VIRAL TRANSCRIPTION 3 39 2.684e-05 0.0009389
132 COCHLEA DEVELOPMENT 3 39 2.684e-05 0.0009389
133 EMBRYONIC ORGAN DEVELOPMENT 6 406 2.65e-05 0.0009389
134 REGULATION OF ORGAN MORPHOGENESIS 5 242 2.77e-05 0.0009618
135 AORTA DEVELOPMENT 3 41 3.124e-05 0.001076
136 CENTRAL NERVOUS SYSTEM DEVELOPMENT 8 872 3.144e-05 0.001076
137 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 9 1152 3.216e-05 0.001092
138 EPIDERMIS DEVELOPMENT 5 253 3.426e-05 0.001155
139 KIDNEY EPITHELIUM DEVELOPMENT 4 125 3.514e-05 0.001176
140 NEGATIVE REGULATION OF STEM CELL DIFFERENTIATION 3 43 3.609e-05 0.0012
141 POSITIVE REGULATION OF BINDING 4 127 3.739e-05 0.001234
142 NEGATIVE REGULATION OF HEMOPOIESIS 4 128 3.856e-05 0.001263
143 REGULATION OF CELL PROLIFERATION 10 1496 3.986e-05 0.001297
144 REGULATION OF EPIDERMAL CELL DIFFERENTIATION 3 45 4.142e-05 0.001338
145 GLIAL CELL DIFFERENTIATION 4 136 4.887e-05 0.001568
146 MUSCLE TISSUE DEVELOPMENT 5 275 5.096e-05 0.001624
147 CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE 4 139 5.321e-05 0.001684
148 CARDIAC CELL DEVELOPMENT 3 49 5.356e-05 0.001684
149 EPIDERMAL CELL DIFFERENTIATION 4 142 5.783e-05 0.001806
150 HEAD DEVELOPMENT 7 709 6.817e-05 0.002115
151 IMMUNE EFFECTOR PROCESS 6 486 7.218e-05 0.002224
152 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 8 983 7.359e-05 0.002253
153 REGULATION OF MUSCLE CELL DIFFERENTIATION 4 152 7.535e-05 0.002288
154 UROGENITAL SYSTEM DEVELOPMENT 5 299 7.574e-05 0.002288
155 OUTFLOW TRACT MORPHOGENESIS 3 56 8.001e-05 0.002402
156 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 5 303 8.064e-05 0.002405
157 POSITIVE REGULATION OF NEURON DIFFERENTIATION 5 306 8.447e-05 0.002504
158 RESPONSE TO OXYGEN LEVELS 5 311 9.118e-05 0.002685
159 REGULATION OF HEMOPOIESIS 5 314 9.539e-05 0.002791
160 REGULATION OF VIRAL TRANSCRIPTION 3 61 0.0001034 0.003006
161 SOMITOGENESIS 3 62 0.0001085 0.003116
162 CARDIAC VENTRICLE MORPHOGENESIS 3 62 0.0001085 0.003116
163 REGULATION OF PROTEIN BINDING 4 168 0.000111 0.003169
164 REGULATION OF EPIDERMIS DEVELOPMENT 3 63 0.0001138 0.003229
165 LOOP OF HENLE DEVELOPMENT 2 11 0.0001186 0.003286
166 NEGATIVE REGULATION OF SPROUTING ANGIOGENESIS 2 11 0.0001186 0.003286
167 NEGATIVE REGULATION OF GLIAL CELL PROLIFERATION 2 11 0.0001186 0.003286
168 VENTRICULAR TRABECULA MYOCARDIUM MORPHOGENESIS 2 11 0.0001186 0.003286
169 GLIOGENESIS 4 175 0.0001299 0.003577
170 FOREBRAIN GENERATION OF NEURONS 3 66 0.0001308 0.003579
171 REGULATION OF DNA TEMPLATED TRANSCRIPTION IN RESPONSE TO STRESS 3 67 0.0001367 0.003721
172 POSITIVE REGULATION BY HOST OF VIRAL TRANSCRIPTION 2 12 0.0001422 0.003739
173 CARDIAC CONDUCTION SYSTEM DEVELOPMENT 2 12 0.0001422 0.003739
174 AMYLOID PRECURSOR PROTEIN METABOLIC PROCESS 2 12 0.0001422 0.003739
175 DISTAL TUBULE DEVELOPMENT 2 12 0.0001422 0.003739
176 LATERAL VENTRICLE DEVELOPMENT 2 12 0.0001422 0.003739
177 POSITIVE REGULATION OF ASTROCYTE DIFFERENTIATION 2 12 0.0001422 0.003739
178 REGULATION OF IMMUNE SYSTEM PROCESS 9 1403 0.0001487 0.003888
179 NEURONAL STEM CELL DIVISION 2 13 0.0001679 0.004224
180 NEGATIVE REGULATION OF OLIGODENDROCYTE DIFFERENTIATION 2 13 0.0001679 0.004224
181 EPITHELIAL CELL DEVELOPMENT 4 186 0.0001643 0.004224
182 VASCULAR SMOOTH MUSCLE CELL DIFFERENTIATION 2 13 0.0001679 0.004224
183 LEFT RIGHT AXIS SPECIFICATION 2 13 0.0001679 0.004224
184 NEUROBLAST DIVISION 2 13 0.0001679 0.004224
185 CELL FATE SPECIFICATION 3 71 0.0001625 0.004224
186 REGULATION OF ESTABLISHMENT OF PLANAR POLARITY INVOLVED IN NEURAL TUBE CLOSURE 2 14 0.0001957 0.00487
187 BETA AMYLOID METABOLIC PROCESS 2 14 0.0001957 0.00487
188 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 8 1135 0.0002001 0.00493
189 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 5 368 0.0002003 0.00493
190 RESPIRATORY SYSTEM DEVELOPMENT 4 197 0.0002047 0.005014
191 SOMITE DEVELOPMENT 3 78 0.0002148 0.005232
192 RESPONSE TO MURAMYL DIPEPTIDE 2 15 0.0002256 0.00544
193 REGULATION OF CELL PROLIFERATION INVOLVED IN HEART MORPHOGENESIS 2 15 0.0002256 0.00544
194 NEGATIVE REGULATION OF GENE EXPRESSION 9 1493 0.0002384 0.005688
195 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 9 1492 0.0002372 0.005688
196 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 4 207 0.0002474 0.005872
197 MORPHOGENESIS OF AN ENDOTHELIUM 2 16 0.0002576 0.006024
198 CARDIAC RIGHT VENTRICLE MORPHOGENESIS 2 16 0.0002576 0.006024
199 APOPTOTIC PROCESS INVOLVED IN MORPHOGENESIS 2 16 0.0002576 0.006024
200 SKIN DEVELOPMENT 4 211 0.0002661 0.00619
201 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 9 1517 0.0002688 0.006222
202 REGULATION OF STRIATED MUSCLE CELL DIFFERENTIATION 3 85 0.0002768 0.006338
203 POSITIVE REGULATION OF CHROMATIN MODIFICATION 3 85 0.0002768 0.006338
204 GLAND DEVELOPMENT 5 395 0.0002779 0.006338
205 MEMBRANE PROTEIN INTRACELLULAR DOMAIN PROTEOLYSIS 2 17 0.0002917 0.006621
206 TISSUE REMODELING 3 87 0.0002965 0.006697
207 CELLULAR COMPONENT MORPHOGENESIS 7 900 0.0002993 0.006728
208 SEGMENTATION 3 89 0.000317 0.007092
209 REGULATION OF NEURON PROJECTION DEVELOPMENT 5 408 0.0003226 0.007182
210 PERICARDIUM DEVELOPMENT 2 18 0.0003279 0.007264
211 NEGATIVE REGULATION OF CELL PROLIFERATION 6 643 0.0003313 0.007305
212 POSITIVE REGULATION OF VIRAL PROCESS 3 92 0.0003495 0.007671
213 TELENCEPHALON DEVELOPMENT 4 228 0.0003572 0.007802
214 REGULATION OF CELL MIGRATION INVOLVED IN SPROUTING ANGIOGENESIS 2 19 0.0003661 0.00796
215 CANONICAL WNT SIGNALING PATHWAY 3 95 0.0003841 0.008312
216 MUSCLE CELL DIFFERENTIATION 4 237 0.0004135 0.008908
217 MEMORY 3 98 0.0004208 0.008981
218 POSITIVE REGULATION OF GROWTH 4 238 0.0004202 0.008981
219 SENSORY ORGAN MORPHOGENESIS 4 239 0.0004269 0.009069
220 LEFT RIGHT PATTERN FORMATION 2 21 0.0004487 0.009363
221 REGULATION OF GLIAL CELL PROLIFERATION 2 21 0.0004487 0.009363
222 APOPTOTIC PROCESS INVOLVED IN DEVELOPMENT 2 21 0.0004487 0.009363
223 COCHLEA MORPHOGENESIS 2 21 0.0004487 0.009363
224 NEURON DEVELOPMENT 6 687 0.0004714 0.009792
NumGOOverlapSizeP ValueAdj. P Value
1 NOTCH BINDING 9 18 4.897e-22 4.549e-19
2 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 11 588 4.252e-10 1.975e-07
3 TRANSCRIPTION COACTIVATOR ACTIVITY 8 296 9.24e-09 2.861e-06
4 RECEPTOR BINDING 13 1476 6.661e-08 1.547e-05
5 BETA CATENIN BINDING 5 84 1.52e-07 2.824e-05
6 CALCIUM ION BINDING 8 697 6.194e-06 0.000959
7 TRANSCRIPTION FACTOR BINDING 7 524 9.819e-06 0.001303
NumGOOverlapSizeP ValueAdj. P Value
1 APICAL PART OF CELL 6 361 1.366e-05 0.003988
2 NUCLEOPLASM PART 8 708 6.948e-06 0.003988
3 CHROMOSOME 8 880 3.357e-05 0.006145
4 CHROMATIN 6 441 4.209e-05 0.006145
5 GOLGI MEMBRANE 7 703 6.461e-05 0.006591
6 APICAL PLASMA MEMBRANE 5 292 6.772e-05 0.006591
7 WNT SIGNALOSOME 2 11 0.0001186 0.009897

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04330_Notch_signaling_pathway 30 47 6.921e-85 1.246e-82
2 hsa04320_Dorso.ventral_axis_formation 4 25 5.089e-08 4.58e-06
3 hsa04310_Wnt_signaling_pathway 5 151 2.809e-06 0.0001685
4 hsa04916_Melanogenesis 4 101 1.518e-05 0.000683
5 hsa04720_Long.term_potentiation 2 70 0.004931 0.1605
6 hsa04520_Adherens_junction 2 73 0.00535 0.1605
7 hsa04350_TGF.beta_signaling_pathway 2 85 0.007188 0.1848
8 hsa04722_Neurotrophin_signaling_pathway 2 127 0.01549 0.3145
9 hsa04110_Cell_cycle 2 128 0.01573 0.3145
10 hsa04390_Hippo_signaling_pathway 2 154 0.02225 0.3686
11 hsa04630_Jak.STAT_signaling_pathway 2 155 0.02252 0.3686

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1

RP11-815I9.4

hsa-miR-103a-3p;hsa-miR-146b-5p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-181b-5p;hsa-miR-186-5p;hsa-miR-18a-3p;hsa-miR-205-5p;hsa-miR-2355-5p;hsa-miR-29b-3p;hsa-miR-30c-5p;hsa-miR-34a-5p;hsa-miR-590-5p 14 NOTCH2 Sponge network 0.004 0.98116 -0.469 0.00039 0.544
2 RP11-193H5.1 hsa-miR-103a-3p;hsa-miR-125a-5p;hsa-miR-130b-5p;hsa-miR-15a-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-18a-3p;hsa-miR-2355-5p;hsa-miR-25-3p;hsa-miR-29b-3p;hsa-miR-7-1-3p 11 NOTCH2 Sponge network -0.426 0.01062 -0.469 0.00039 0.484
3 BHLHE40-AS1 hsa-miR-17-5p;hsa-miR-181b-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-450b-5p;hsa-miR-576-5p;hsa-miR-590-5p;hsa-miR-92a-3p 11 KAT2B Sponge network -0.932 0 -2.053 0 0.447
4 RP1-122P22.2 hsa-miR-103a-3p;hsa-miR-125a-5p;hsa-miR-146b-5p;hsa-miR-16-1-3p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-183-5p;hsa-miR-18a-3p;hsa-miR-205-5p;hsa-miR-2355-5p 10 NOTCH2 Sponge network -1.073 6.0E-5 -0.469 0.00039 0.411
5

CTD-2008P7.9

hsa-miR-17-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-29a-5p;hsa-miR-450b-5p;hsa-miR-576-5p 11 KAT2B Sponge network -1.202 0.00093 -2.053 0 0.328
6

EMX2OS

hsa-miR-106b-5p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-29a-5p;hsa-miR-576-5p;hsa-miR-92a-3p;hsa-miR-92b-3p;hsa-miR-93-5p;hsa-miR-944 14 KAT2B Sponge network -1.459 1.0E-5 -2.053 0 0.323
7

LINC00900

hsa-miR-106b-5p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-576-5p;hsa-miR-590-5p;hsa-miR-92a-3p;hsa-miR-92b-3p;hsa-miR-93-5p 13 KAT2B Sponge network -1.803 0 -2.053 0 0.32
8 RP11-284N8.3 hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-576-5p;hsa-miR-590-5p;hsa-miR-93-5p;hsa-miR-944 10 KAT2B Sponge network 0.003 0.99478 -2.053 0 0.317
9 AC144831.1 hsa-miR-103a-3p;hsa-miR-130b-5p;hsa-miR-146b-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-183-5p;hsa-miR-18a-3p;hsa-miR-2355-5p;hsa-miR-25-3p;hsa-miR-424-5p;hsa-miR-7-1-3p 12 NOTCH2 Sponge network -1.546 0 -0.469 0.00039 0.313
10

CTD-2015G9.2

hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-450b-5p;hsa-miR-542-3p;hsa-miR-576-5p;hsa-miR-93-5p 11 KAT2B Sponge network -3.112 5.0E-5 -2.053 0 0.311
11

MAGI2-AS3

hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-193b-3p;hsa-miR-20a-5p;hsa-miR-2355-3p;hsa-miR-25-3p;hsa-miR-26b-5p;hsa-miR-29b-1-5p;hsa-miR-30c-5p;hsa-miR-339-5p;hsa-miR-342-3p;hsa-miR-582-3p;hsa-miR-590-3p;hsa-miR-92a-3p 14 EP300 Sponge network -0.939 4.0E-5 -0.038 0.77828 0.297
12

CTD-2015G9.2

hsa-miR-103a-3p;hsa-miR-130b-5p;hsa-miR-146b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-18a-3p;hsa-miR-205-5p;hsa-miR-2355-5p;hsa-miR-25-3p;hsa-miR-342-3p;hsa-miR-7-1-3p;hsa-miR-708-3p 15 NOTCH2 Sponge network -3.112 5.0E-5 -0.469 0.00039 0.286
13

RP11-456K23.1

hsa-miR-106b-5p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-25-3p;hsa-miR-429;hsa-miR-590-5p;hsa-miR-92a-3p;hsa-miR-92b-3p;hsa-miR-93-5p 13 KAT2B Sponge network -0.223 0.27461 -2.053 0 0.262
14

RP4-798P15.3

hsa-miR-103a-3p;hsa-miR-146b-5p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-18a-3p;hsa-miR-205-5p;hsa-miR-2355-5p;hsa-miR-455-5p;hsa-miR-590-5p;hsa-miR-7-1-3p 12 NOTCH2 Sponge network -1.213 0.00098 -0.469 0.00039 0.259

Quest ID: 88bd54cb3020c6ecd272b2a5e661def4