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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-17-5p AADAC 0.7 2.0E-5 -1.53 0 MirTarget -0.19 0.04679 NA
2 hsa-miR-17-5p AAK1 0.7 2.0E-5 0.62 0 TargetScan -0.11 0.0001 NA
3 hsa-miR-17-5p ABHD2 0.7 2.0E-5 -1.2 0 TargetScan; miRNATAP -0.33 0 NA
4 hsa-miR-17-5p ABHD5 0.7 2.0E-5 -0.6 0 MirTarget; TargetScan -0.15 0 NA
5 hsa-miR-17-5p ACBD5 0.7 2.0E-5 -0.75 0 TargetScan -0.23 0 NA
6 hsa-miR-17-5p ACER2 0.7 2.0E-5 -1.22 0 TargetScan -0.41 0 NA
7 hsa-miR-17-5p ACER3 0.7 2.0E-5 0.02 0.84604 mirMAP -0.1 0.00064 NA
8 hsa-miR-17-5p ACOT2 0.7 2.0E-5 -1.29 0 miRNAWalker2 validate -0.19 0.00011 NA
9 hsa-miR-17-5p ACOX1 0.7 2.0E-5 -1.16 0 mirMAP -0.22 0 NA
10 hsa-miR-17-5p ACSL6 0.7 2.0E-5 0.39 0.26458 mirMAP -0.37 0.00035 NA
11 hsa-miR-17-5p ACTR3C 0.7 2.0E-5 -0.99 0 mirMAP -0.25 0 NA
12 hsa-miR-17-5p ADAM9 0.7 2.0E-5 0.47 0.00581 TargetScan; miRNATAP -0.2 8.0E-5 NA
13 hsa-miR-17-5p ADAMTS5 0.7 2.0E-5 -0.16 0.36499 TargetScan -0.11 0.03358 NA
14 hsa-miR-17-5p ADAMTSL2 0.7 2.0E-5 -2.68 0 TargetScan -0.28 0.00562 NA
15 hsa-miR-17-5p ADARB1 0.7 2.0E-5 -0.13 0.22208 miRNAWalker2 validate; MirTarget -0.13 7.0E-5 NA
16 hsa-miR-17-5p ADCY1 0.7 2.0E-5 -2.7 0 mirMAP -0.24 0.03129 NA
17 hsa-miR-17-5p ADCY9 0.7 2.0E-5 -0.11 0.30518 mirMAP -0.12 0.00011 NA
18 hsa-miR-17-5p ADIPOR2 0.7 2.0E-5 -0.68 0 TargetScan -0.13 8.0E-5 NA
19 hsa-miR-17-5p ADRA1B 0.7 2.0E-5 -2.34 0 TargetScan -0.56 0 NA
20 hsa-miR-17-5p AEN 0.7 2.0E-5 0.28 0.01239 MirTarget; TargetScan -0.11 0.00144 NA
21 hsa-miR-17-5p AFF1 0.7 2.0E-5 -0.71 0 TargetScan -0.14 3.0E-5 NA
22 hsa-miR-17-5p AFF4 0.7 2.0E-5 -0.64 0 TargetScan; miRNATAP -0.14 0 NA
23 hsa-miR-17-5p AGFG2 0.7 2.0E-5 -0.02 0.87061 TargetScan; miRNATAP -0.11 0.00181 NA
24 hsa-miR-17-5p AHRR 0.7 2.0E-5 0.37 0.09373 MirTarget; TargetScan -0.14 0.03047 NA
25 hsa-miR-17-5p AKAP11 0.7 2.0E-5 -0.7 0 MirTarget; TargetScan -0.19 0 NA
26 hsa-miR-17-5p AKAP13 0.7 2.0E-5 -0.32 0.00142 MirTarget; TargetScan; mirMAP; miRNATAP -0.16 0 NA
27 hsa-miR-17-5p AKAP9 0.7 2.0E-5 -0.79 0 TargetScan -0.18 2.0E-5 NA
28 hsa-miR-17-5p AKT3 0.7 2.0E-5 -0.66 0.00047 TargetScan; miRNATAP -0.29 0 NA
29 hsa-miR-17-5p AKTIP 0.7 2.0E-5 -0.37 0.00054 MirTarget; TargetScan; miRNATAP -0.28 0 NA
30 hsa-miR-17-5p ANKFY1 0.7 2.0E-5 -0.58 0 MirTarget; TargetScan -0.15 0 NA
31 hsa-miR-17-5p ANKIB1 0.7 2.0E-5 0.07 0.50551 TargetScan; miRNATAP -0.12 4.0E-5 NA
32 hsa-miR-17-5p ANKRD17 0.7 2.0E-5 -0.34 0.00103 TargetScan -0.14 0 NA
33 hsa-miR-17-5p ANKRD29 0.7 2.0E-5 1.13 4.0E-5 MirTarget; TargetScan -0.48 0 NA
34 hsa-miR-17-5p ANKRD50 0.7 2.0E-5 -0.25 0.04433 MirTarget; TargetScan; miRNATAP -0.22 0 NA
35 hsa-miR-17-5p ANO6 0.7 2.0E-5 -0.29 0.00464 MirTarget; TargetScan; miRNATAP -0.14 1.0E-5 NA
36 hsa-miR-17-5p AP3S2 0.7 2.0E-5 -0.33 4.0E-5 mirMAP -0.1 1.0E-5 NA
37 hsa-miR-17-5p APBB2 0.7 2.0E-5 -0.24 0.03085 MirTarget; TargetScan; miRNATAP -0.23 0 NA
38 hsa-miR-17-5p APCDD1 0.7 2.0E-5 -1.3 0.00043 MirTarget; TargetScan -0.27 0.01168 NA
39 hsa-miR-17-5p AR 0.7 2.0E-5 -2.66 0 mirMAP -0.93 0 23095762 miR 17 5p targets the p300/CBP associated factor and modulates androgen receptor transcriptional activity in cultured prostate cancer cells; Targeting of the 3'-untranslated region of PCAF mRNA by miR-17-5p caused translational suppression and RNA degradation and consequently modulation of AR transcriptional activity in PCa cells; Targeting of PCAF by miR-17-5p modulates AR transcriptional activity and cell growth in cultured PCa cells
40 hsa-miR-17-5p ARAP2 0.7 2.0E-5 -1.13 0 MirTarget; TargetScan -0.19 0.00017 NA
41 hsa-miR-17-5p ARHGAP10 0.7 2.0E-5 -1.87 0 miRNAWalker2 validate -0.37 0 NA
42 hsa-miR-17-5p ARHGAP12 0.7 2.0E-5 0.04 0.72248 TargetScan; miRNATAP -0.1 0.00059 NA
43 hsa-miR-17-5p ARHGAP23 0.7 2.0E-5 -0.14 0.32985 mirMAP -0.19 1.0E-5 NA
44 hsa-miR-17-5p ARHGAP24 0.7 2.0E-5 -0.99 0 MirTarget -0.29 0 NA
45 hsa-miR-17-5p ARHGAP31 0.7 2.0E-5 -0.42 0.00347 TargetScan -0.25 0 NA
46 hsa-miR-17-5p ARHGAP5 0.7 2.0E-5 -0.39 8.0E-5 miRNAWalker2 validate -0.17 0 NA
47 hsa-miR-17-5p ARHGEF10 0.7 2.0E-5 0.05 0.78887 TargetScan -0.27 0 NA
48 hsa-miR-17-5p ARIH1 0.7 2.0E-5 -0.13 0.06993 miRNAWalker2 validate -0.12 0 NA
49 hsa-miR-17-5p ARL10 0.7 2.0E-5 -0.42 0.01556 mirMAP -0.12 0.01623 NA
50 hsa-miR-17-5p ARL13B 0.7 2.0E-5 -0.32 0.01196 MirTarget -0.13 0.00029 NA
51 hsa-miR-17-5p ARSD 0.7 2.0E-5 -1.16 0 mirMAP -0.39 0 NA
52 hsa-miR-17-5p ARSJ 0.7 2.0E-5 -1.41 0 TargetScan -0.5 0 NA
53 hsa-miR-17-5p ASPA 0.7 2.0E-5 -2.88 0 mirMAP -0.3 0.00071 NA
54 hsa-miR-17-5p ASXL2 0.7 2.0E-5 -0.29 0.18051 TargetScan -0.24 0.00015 NA
55 hsa-miR-17-5p ASXL3 0.7 2.0E-5 -2.69 0 TargetScan -0.47 2.0E-5 NA
56 hsa-miR-17-5p ATE1 0.7 2.0E-5 -0.6 0.0009 MirTarget; TargetScan -0.17 0.00187 NA
57 hsa-miR-17-5p ATF3 0.7 2.0E-5 -1.88 0 miRNAWalker2 validate -0.29 0 NA
58 hsa-miR-17-5p ATL3 0.7 2.0E-5 0.13 0.25255 MirTarget; TargetScan; miRNATAP -0.2 0 NA
59 hsa-miR-17-5p ATOH8 0.7 2.0E-5 -2.68 0 TargetScan -0.7 0 NA
60 hsa-miR-17-5p ATP1A2 0.7 2.0E-5 0.51 0.11121 MirTarget; TargetScan -0.36 0.00013 NA
61 hsa-miR-17-5p ATRX 0.7 2.0E-5 -0.07 0.48759 miRNAWalker2 validate; mirMAP -0.12 3.0E-5 NA
62 hsa-miR-17-5p ATXN1L 0.7 2.0E-5 0.09 0.38956 TargetScan; miRNATAP -0.17 0 NA
63 hsa-miR-17-5p ATXN7L1 0.7 2.0E-5 -0.24 0.06065 TargetScan -0.35 0 NA
64 hsa-miR-17-5p BBX 0.7 2.0E-5 -0.07 0.54321 MirTarget; TargetScan; miRNATAP -0.18 0 NA
65 hsa-miR-17-5p BCL2 0.7 2.0E-5 -0.35 0.02497 miRNAWalker2 validate; miRTarBase -0.31 0 25435430 Combined overexpression of miR-16 and miR-17 greatly reduced Beclin-1 and Bcl-2 expressions respectively; miR-17 overexpression reduced cytoprotective autophagy by targeting Beclin-1 whereas overexpression of miR-16 potentiated paclitaxel induced apoptotic cell death by inhibiting anti-apoptotic protein Bcl-2
66 hsa-miR-17-5p BHLHE41 0.7 2.0E-5 -0.4 0.15906 TargetScan; miRNATAP -0.37 1.0E-5 NA
67 hsa-miR-17-5p BMP2K 0.7 2.0E-5 -0.82 0 TargetScan -0.17 1.0E-5 NA
68 hsa-miR-17-5p BMPR2 0.7 2.0E-5 -0.74 0 miRNAWalker2 validate; MirTarget; TargetScan; miRNATAP -0.26 0 NA
69 hsa-miR-17-5p BNC2 0.7 2.0E-5 -0.39 0.08973 TargetScan; miRNATAP -0.34 0 NA
70 hsa-miR-17-5p BNIP3L 0.7 2.0E-5 -0.67 0 MirTarget; TargetScan -0.19 0 NA
71 hsa-miR-17-5p BTN3A1 0.7 2.0E-5 0.33 0.01478 miRNAWalker2 validate -0.28 0 NA
72 hsa-miR-17-5p BVES 0.7 2.0E-5 -0.6 0.00365 TargetScan -0.2 0.00085 NA
73 hsa-miR-17-5p C16orf52 0.7 2.0E-5 -0.5 0 TargetScan; miRNATAP -0.24 0 NA
74 hsa-miR-17-5p C16orf70 0.7 2.0E-5 -0.77 0 TargetScan -0.14 5.0E-5 NA
75 hsa-miR-17-5p C16orf72 0.7 2.0E-5 -0.44 0 TargetScan -0.13 0 NA
76 hsa-miR-17-5p C18orf25 0.7 2.0E-5 -0.11 0.11389 mirMAP -0.11 0 NA
77 hsa-miR-17-5p C2CD2 0.7 2.0E-5 0.04 0.76174 MirTarget; TargetScan; miRNATAP -0.17 0 NA
78 hsa-miR-17-5p C2orf69 0.7 2.0E-5 -0.19 0.04079 TargetScan -0.21 0 NA
79 hsa-miR-17-5p C3orf70 0.7 2.0E-5 0.49 0.00136 TargetScan -0.1 0.0268 NA
80 hsa-miR-17-5p CA5B 0.7 2.0E-5 0.77 1.0E-5 mirMAP -0.17 0.00077 NA
81 hsa-miR-17-5p CALD1 0.7 2.0E-5 -0.53 0 TargetScan; miRNATAP -0.23 0 NA
82 hsa-miR-17-5p CAMTA2 0.7 2.0E-5 -0.35 8.0E-5 MirTarget; TargetScan -0.11 1.0E-5 NA
83 hsa-miR-17-5p CASC4 0.7 2.0E-5 -0.46 0 MirTarget -0.21 0 NA
84 hsa-miR-17-5p CASK 0.7 2.0E-5 0.43 0.00011 mirMAP -0.22 0 NA
85 hsa-miR-17-5p CBX7 0.7 2.0E-5 -0.08 0.52937 mirMAP -0.25 0 NA
86 hsa-miR-17-5p CC2D1A 0.7 2.0E-5 0.26 0.00869 MirTarget; TargetScan; miRNATAP -0.15 0 NA
87 hsa-miR-17-5p CCBE1 0.7 2.0E-5 -5.46 0 mirMAP -0.59 0 NA
88 hsa-miR-17-5p CCDC103 0.7 2.0E-5 -0.03 0.84263 mirMAP -0.15 0.00403 NA
89 hsa-miR-17-5p CCDC25 0.7 2.0E-5 -1.1 0 TargetScan -0.18 0 NA
90 hsa-miR-17-5p CCND1 0.7 2.0E-5 -0.9 1.0E-5 miRNAWalker2 validate; MirTarget; TargetScan; miRNATAP -0.34 0 26431674 Bioinformatics Prediction and In Vitro Analysis Revealed That miR 17 Targets Cyclin D1 mRNA in Triple Negative Breast Cancer Cells; In this study using bioinformatic analyses miR-17 was selected as it targets the 3'UTR of CCND1 gene with the highest score; After lentiviral transduction of miR-17 to the target cells gene expression analysis showed decreased expression of CCND1 gene
91 hsa-miR-17-5p CCND2 0.7 2.0E-5 0.36 0.03656 miRNAWalker2 validate; miRTarBase; TargetScan; miRNATAP -0.11 0.02358 NA
92 hsa-miR-17-5p CD226 0.7 2.0E-5 -2.15 0 TargetScan -0.19 0.0112 NA
93 hsa-miR-17-5p CD274 0.7 2.0E-5 -1.27 0 MirTarget; TargetScan; miRNATAP -0.44 0 NA
94 hsa-miR-17-5p CD69 0.7 2.0E-5 -1.75 0 TargetScan; miRNATAP -0.17 0.0246 NA
95 hsa-miR-17-5p CDC37L1 0.7 2.0E-5 -1.68 0 MirTarget; TargetScan; miRNATAP -0.38 0 NA
96 hsa-miR-17-5p CDH19 0.7 2.0E-5 -4.11 0 TargetScan -0.37 0.00314 NA
97 hsa-miR-17-5p CDK6 0.7 2.0E-5 -0.31 0.22057 TargetScan; mirMAP -0.33 0 NA
98 hsa-miR-17-5p CDKN1A 0.7 2.0E-5 -0.77 6.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; TargetScan; miRNATAP -0.3 0 26482648; 24989082 The low expressions of miR-17 and miR-92 families can maintain cisplatin resistance through the regulation of CDKN1A and RAD21;According to PicTar and Miranda algorithms which predicted CDKN1A p21 as a putative target of miR-17 a luciferase assay was performed and revealed that miR-17 directly targets the 3'-UTR of p21 mRNA
99 hsa-miR-17-5p CELF2 0.7 2.0E-5 -0.74 8.0E-5 TargetScan -0.18 0.00125 NA
100 hsa-miR-17-5p CELSR2 0.7 2.0E-5 0.41 0.02717 TargetScan; miRNATAP -0.12 0.02326 NA
101 hsa-miR-17-5p CEP120 0.7 2.0E-5 -0.39 2.0E-5 MirTarget; TargetScan; miRNATAP -0.11 2.0E-5 NA
102 hsa-miR-17-5p CEP97 0.7 2.0E-5 0.29 0.07184 MirTarget; TargetScan; miRNATAP -0.13 0.00468 NA
103 hsa-miR-17-5p CFL2 0.7 2.0E-5 -1.18 0 MirTarget; TargetScan; miRNATAP -0.2 0 NA
104 hsa-miR-17-5p CHD9 0.7 2.0E-5 -0.51 3.0E-5 MirTarget; TargetScan; miRNATAP -0.29 0 NA
105 hsa-miR-17-5p CHIC1 0.7 2.0E-5 -1.1 1.0E-5 TargetScan -0.24 0.00094 NA
106 hsa-miR-17-5p CHST7 0.7 2.0E-5 -1.56 0 TargetScan -0.2 0.00092 NA
107 hsa-miR-17-5p CHTF8 0.7 2.0E-5 -0.4 0 miRNAWalker2 validate -0.13 0 NA
108 hsa-miR-17-5p CIITA 0.7 2.0E-5 0.27 0.18011 mirMAP -0.16 0.00664 NA
109 hsa-miR-17-5p CLIC6 0.7 2.0E-5 -3.64 0 mirMAP -0.66 0 NA
110 hsa-miR-17-5p CLIP4 0.7 2.0E-5 -0.22 0.43954 MirTarget; TargetScan -0.3 0.00045 NA
111 hsa-miR-17-5p CLOCK 0.7 2.0E-5 -0.53 0.00745 MirTarget; TargetScan -0.32 0 NA
112 hsa-miR-17-5p CLUAP1 0.7 2.0E-5 0.14 0.12444 mirMAP -0.12 0 NA
113 hsa-miR-17-5p CMKLR1 0.7 2.0E-5 -0.79 1.0E-5 TargetScan -0.17 0.001 NA
114 hsa-miR-17-5p CMPK1 0.7 2.0E-5 -0.68 0 MirTarget; TargetScan; miRNATAP -0.16 0 NA
115 hsa-miR-17-5p CNDP1 0.7 2.0E-5 -6.39 0 mirMAP -0.84 0 NA
116 hsa-miR-17-5p CNN1 0.7 2.0E-5 0.41 0.09282 TargetScan -0.28 6.0E-5 NA
117 hsa-miR-17-5p CNOT6L 0.7 2.0E-5 -0.53 0 TargetScan -0.15 0 NA
118 hsa-miR-17-5p CNTNAP3 0.7 2.0E-5 0.11 0.74285 MirTarget -0.46 0 NA
119 hsa-miR-17-5p COL4A3 0.7 2.0E-5 -0.93 0.00622 MirTarget; TargetScan; miRNATAP -0.29 0.00372 NA
120 hsa-miR-17-5p CPEB3 0.7 2.0E-5 -2.74 0 TargetScan; miRNATAP -0.53 0 NA
121 hsa-miR-17-5p CPEB4 0.7 2.0E-5 -1.06 0 mirMAP -0.27 0 NA
122 hsa-miR-17-5p CREB5 0.7 2.0E-5 0 0.99313 MirTarget; TargetScan; miRNATAP -0.13 0.02492 NA
123 hsa-miR-17-5p CRIM1 0.7 2.0E-5 -0.43 0.03963 MirTarget; TargetScan; miRNATAP -0.5 0 NA
124 hsa-miR-17-5p CRK 0.7 2.0E-5 -0.66 0 MirTarget; TargetScan; miRNATAP -0.12 9.0E-5 NA
125 hsa-miR-17-5p CRY2 0.7 2.0E-5 -0.23 0.06667 MirTarget; TargetScan; miRNATAP -0.18 0 NA
126 hsa-miR-17-5p CRYBG3 0.7 2.0E-5 -0.7 0.01151 MirTarget; TargetScan; miRNATAP -0.52 0 NA
127 hsa-miR-17-5p CSF1 0.7 2.0E-5 -0.59 0.00153 TargetScan; miRNATAP -0.24 1.0E-5 NA
128 hsa-miR-17-5p CSGALNACT1 0.7 2.0E-5 0.19 0.22912 MirTarget; TargetScan -0.22 0 NA
129 hsa-miR-17-5p CXCL14 0.7 2.0E-5 -6.87 0 TargetScan -0.75 0 NA
130 hsa-miR-17-5p CXCL6 0.7 2.0E-5 -3.43 0 MirTarget -0.69 5.0E-5 NA
131 hsa-miR-17-5p CXorf23 0.7 2.0E-5 0.43 1.0E-5 mirMAP -0.11 6.0E-5 NA
132 hsa-miR-17-5p CXorf56 0.7 2.0E-5 -0.01 0.97138 TargetScan -0.2 3.0E-5 NA
133 hsa-miR-17-5p CYBRD1 0.7 2.0E-5 -1.29 0 MirTarget; TargetScan -0.37 0 NA
134 hsa-miR-17-5p CYP2U1 0.7 2.0E-5 -1.02 0 MirTarget; TargetScan -0.41 0 NA
135 hsa-miR-17-5p DAZAP2 0.7 2.0E-5 -0.39 0 MirTarget; TargetScan; miRNATAP -0.12 0 NA
136 hsa-miR-17-5p DCAF8 0.7 2.0E-5 -0.03 0.75166 TargetScan; miRNATAP -0.12 0 NA
137 hsa-miR-17-5p DCUN1D3 0.7 2.0E-5 -1.25 0 MirTarget; TargetScan -0.17 0 NA
138 hsa-miR-17-5p DGKE 0.7 2.0E-5 -0.86 0 MirTarget -0.25 1.0E-5 NA
139 hsa-miR-17-5p DIP2C 0.7 2.0E-5 -0.78 5.0E-5 TargetScan -0.3 0 NA
140 hsa-miR-17-5p DIRC2 0.7 2.0E-5 -0.06 0.49043 MirTarget; TargetScan; miRNATAP -0.24 0 NA
141 hsa-miR-17-5p DIXDC1 0.7 2.0E-5 -1.03 0 mirMAP -0.3 0 NA
142 hsa-miR-17-5p DLG2 0.7 2.0E-5 -1.95 0 mirMAP -0.41 0 NA
143 hsa-miR-17-5p DNAJB9 0.7 2.0E-5 -0.63 0 TargetScan; miRNATAP -0.24 0 NA
144 hsa-miR-17-5p DNAJC15 0.7 2.0E-5 -0.71 0 TargetScan -0.15 0.00097 NA
145 hsa-miR-17-5p DNAJC27 0.7 2.0E-5 -0.35 0.00026 miRNAWalker2 validate; miRTarBase; MirTarget; TargetScan; miRNATAP -0.18 0 NA
146 hsa-miR-17-5p DNAL1 0.7 2.0E-5 -0.09 0.30099 TargetScan -0.14 0 NA
147 hsa-miR-17-5p DNMBP 0.7 2.0E-5 -0.66 0 miRNAWalker2 validate -0.13 0.00031 NA
148 hsa-miR-17-5p DOCK4 0.7 2.0E-5 -0.2 0.07305 MirTarget; TargetScan -0.14 1.0E-5 NA
149 hsa-miR-17-5p DPF3 0.7 2.0E-5 -2.59 0 TargetScan -0.51 0 NA
150 hsa-miR-17-5p DPP8 0.7 2.0E-5 -0.27 0.06918 mirMAP -0.13 0.00459 NA
NumGOOverlapSizeP ValueAdj. P Value
1 TISSUE DEVELOPMENT 116 1518 1.958e-15 9.112e-12
2 POSITIVE REGULATION OF CATALYTIC ACTIVITY 110 1518 4.046e-13 9.412e-10
3 CARDIOVASCULAR SYSTEM DEVELOPMENT 70 788 1.554e-12 1.808e-09
4 CIRCULATORY SYSTEM DEVELOPMENT 70 788 1.554e-12 1.808e-09
5 POSITIVE REGULATION OF MOLECULAR FUNCTION 120 1791 5.992e-12 5.576e-09
6 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 118 1784 2.144e-11 1.663e-08
7 INTRACELLULAR SIGNAL TRANSDUCTION 106 1572 8.954e-11 5.208e-08
8 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 35 278 8.699e-11 5.208e-08
9 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 62 740 3.476e-10 1.797e-07
10 HEART DEVELOPMENT 46 466 4.317e-10 2.009e-07
11 ORGAN MORPHOGENESIS 67 841 5.478e-10 2.317e-07
12 EPITHELIUM DEVELOPMENT 72 945 8.473e-10 3.285e-07
13 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 58 689 1.115e-09 3.706e-07
14 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 48 513 1.08e-09 3.706e-07
15 TISSUE MORPHOGENESIS 49 533 1.303e-09 4.042e-07
16 TUBE DEVELOPMENT 50 552 1.455e-09 4.232e-07
17 REGULATION OF CELL DIFFERENTIATION 98 1492 2.062e-09 5.644e-07
18 CELL DEVELOPMENT 94 1426 3.863e-09 9.921e-07
19 REGULATION OF PHOSPHORUS METABOLIC PROCESS 103 1618 4.051e-09 9.921e-07
20 VASCULATURE DEVELOPMENT 44 469 5.018e-09 1.167e-06
21 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 74 1036 7.981e-09 1.688e-06
22 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 74 1036 7.981e-09 1.688e-06
23 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 96 1492 8.733e-09 1.767e-06
24 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 104 1672 1.145e-08 2.22e-06
25 MUSCLE TISSUE DEVELOPMENT 31 275 1.516e-08 2.822e-06
26 NEGATIVE REGULATION OF GENE EXPRESSION 95 1493 1.823e-08 3.262e-06
27 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 102 1656 2.669e-08 4.436e-06
28 REGULATION OF CELLULAR COMPONENT MOVEMENT 59 771 2.67e-08 4.436e-06
29 POSITIVE REGULATION OF LOCOMOTION 39 420 4.996e-08 8.016e-06
30 REGULATION OF GTPASE ACTIVITY 53 673 5.564e-08 8.629e-06
31 POSITIVE REGULATION OF GENE EXPRESSION 104 1733 7.136e-08 1.038e-05
32 REGULATION OF PROTEIN MODIFICATION PROCESS 103 1710 6.941e-08 1.038e-05
33 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 76 1135 7.459e-08 1.052e-05
34 REGULATION OF KINASE ACTIVITY 58 776 7.953e-08 1.088e-05
35 REGULATION OF HYDROLASE ACTIVITY 85 1327 8.433e-08 1.121e-05
36 SKELETAL SYSTEM DEVELOPMENT 40 455 1.472e-07 1.86e-05
37 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 108 1848 1.479e-07 1.86e-05
38 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 106 1805 1.55e-07 1.898e-05
39 CELLULAR COMPONENT MORPHOGENESIS 63 900 2.281e-07 2.721e-05
40 POSITIVE REGULATION OF KINASE ACTIVITY 41 482 2.492e-07 2.854e-05
41 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 68 1004 2.515e-07 2.854e-05
42 POSITIVE REGULATION OF HYDROLASE ACTIVITY 63 905 2.769e-07 2.996e-05
43 RESPONSE TO ENDOGENOUS STIMULUS 89 1450 2.711e-07 2.996e-05
44 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 92 1517 2.845e-07 3.009e-05
45 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 68 1008 2.91e-07 3.009e-05
46 MUSCLE STRUCTURE DEVELOPMENT 38 432 2.977e-07 3.012e-05
47 BLOOD VESSEL MORPHOGENESIS 34 364 3.149e-07 3.117e-05
48 NEURON PROJECTION MORPHOGENESIS 36 402 3.973e-07 3.852e-05
49 NEGATIVE REGULATION OF CELL PROLIFERATION 49 643 4.759e-07 4.52e-05
50 REGULATION OF TRANSFERASE ACTIVITY 64 946 6.021e-07 5.603e-05
51 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 47 616 7.913e-07 7.22e-05
52 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 64 957 8.954e-07 8.012e-05
53 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 79 1275 9.459e-07 8.304e-05
54 MORPHOGENESIS OF AN EPITHELIUM 35 400 9.886e-07 8.518e-05
55 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 33 368 1.172e-06 9.809e-05
56 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 22 190 1.181e-06 9.809e-05
57 NEGATIVE REGULATION OF CELL COMMUNICATION 74 1192 2.004e-06 0.0001636
58 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 64 983 2.206e-06 0.000177
59 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 24 229 2.363e-06 0.0001863
60 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 21 184 2.596e-06 0.0002013
61 EPITHELIAL CELL DEVELOPMENT 21 186 3.089e-06 0.0002356
62 HEAD DEVELOPMENT 50 709 3.423e-06 0.0002569
63 POSITIVE REGULATION OF RESPONSE TO STIMULUS 106 1929 3.571e-06 0.0002596
64 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 15 103 3.534e-06 0.0002596
65 TRANSITION METAL ION HOMEOSTASIS 15 106 5.086e-06 0.0003585
66 TUBE MORPHOGENESIS 29 323 5.052e-06 0.0003585
67 NEUROGENESIS 82 1402 5.47e-06 0.0003799
68 NEURON PROJECTION DEVELOPMENT 41 545 5.682e-06 0.0003888
69 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 12 70 5.962e-06 0.000402
70 REGULATION OF CELL PROLIFERATION 86 1496 6.185e-06 0.0004112
71 TELENCEPHALON DEVELOPMENT 23 228 7.239e-06 0.0004744
72 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 57 876 8.242e-06 0.0005327
73 LOCOMOTION 68 1114 9.363e-06 0.0005968
74 UROGENITAL SYSTEM DEVELOPMENT 27 299 9.569e-06 0.0006017
75 CARDIAC MUSCLE TISSUE DEVELOPMENT 17 140 1.009e-05 0.0006259
76 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 79 1360 1.055e-05 0.0006461
77 BONE DEVELOPMENT 18 156 1.143e-05 0.0006759
78 OSSIFICATION 24 251 1.148e-05 0.0006759
79 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 69 1142 1.124e-05 0.0006759
80 MUSCLE CELL DIFFERENTIATION 23 237 1.367e-05 0.000795
81 CENTRAL NERVOUS SYSTEM DEVELOPMENT 56 872 1.445e-05 0.0008303
82 CARDIAC CHAMBER DEVELOPMENT 17 144 1.47e-05 0.0008339
83 CHEMICAL HOMEOSTASIS 56 874 1.543e-05 0.000865
84 REGULATION OF CIRCADIAN RHYTHM 14 103 1.673e-05 0.0009266
85 MESONEPHROS DEVELOPMENT 13 90 1.715e-05 0.0009387
86 VENTRICULAR SEPTUM DEVELOPMENT 10 54 1.758e-05 0.0009511
87 HOMEOSTATIC PROCESS 77 1337 1.854e-05 0.0009918
88 PROTEIN PHOSPHORYLATION 59 944 1.894e-05 0.001002
89 REGULATION OF OSSIFICATION 19 178 2.017e-05 0.001054
90 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 52 799 2.059e-05 0.001064
91 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 11 67 2.222e-05 0.001124
92 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 52 801 2.202e-05 0.001124
93 HEART MORPHOGENESIS 21 212 2.357e-05 0.001179
94 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 15 121 2.589e-05 0.001282
95 CELLULAR RESPONSE TO EXTERNAL STIMULUS 24 264 2.648e-05 0.001297
96 EMBRYO DEVELOPMENT 56 894 2.914e-05 0.001412
97 NEURON DIFFERENTIATION 55 874 3.03e-05 0.001454
98 FOREBRAIN DEVELOPMENT 29 357 3.348e-05 0.001567
99 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 35 470 3.368e-05 0.001567
100 CENTRAL NERVOUS SYSTEM NEURON AXONOGENESIS 7 27 3.321e-05 0.001567
101 CELL PROJECTION ORGANIZATION 56 902 3.726e-05 0.001717
102 BIOLOGICAL ADHESION 62 1032 3.774e-05 0.001722
103 KIDNEY EPITHELIUM DEVELOPMENT 15 125 3.812e-05 0.001722
104 GLAND MORPHOGENESIS 13 97 3.873e-05 0.001733
105 EPITHELIAL CELL DIFFERENTIATION 36 495 4.282e-05 0.001897
106 CARDIAC SEPTUM DEVELOPMENT 12 85 4.534e-05 0.001935
107 POSITIVE REGULATION OF CELL COMMUNICATION 84 1532 4.469e-05 0.001935
108 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 78 1395 4.477e-05 0.001935
109 POSITIVE REGULATION OF CELL DIFFERENTIATION 52 823 4.502e-05 0.001935
110 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 36 498 4.851e-05 0.002052
111 EMBRYONIC MORPHOGENESIS 38 539 5.162e-05 0.002164
112 RESPONSE TO HORMONE 55 893 5.421e-05 0.002252
113 RESPONSE TO OXYGEN CONTAINING COMPOUND 77 1381 5.514e-05 0.00227
114 VESICLE CYTOSKELETAL TRAFFICKING 8 39 5.677e-05 0.002297
115 TRABECULA MORPHOGENESIS 8 39 5.677e-05 0.002297
116 PROTEIN POLYUBIQUITINATION 22 243 6.03e-05 0.002419
117 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 34 465 6.249e-05 0.002485
118 NEURON DEVELOPMENT 45 687 6.383e-05 0.002517
119 REGULATION OF HOMEOSTATIC PROCESS 33 447 6.635e-05 0.002594
120 REGULATION OF OSTEOCLAST DIFFERENTIATION 10 63 7.04e-05 0.002713
121 CELLULAR RESPONSE TO ABIOTIC STIMULUS 23 263 7.055e-05 0.002713
122 CYTOSKELETON ORGANIZATION 52 838 7.167e-05 0.002733
123 PROTEIN UBIQUITINATION 42 629 7.291e-05 0.002736
124 REGULATION OF CELL ADHESION 42 629 7.291e-05 0.002736
125 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 102 1977 7.384e-05 0.002748
126 CARDIAC CHAMBER MORPHOGENESIS 13 104 8.096e-05 0.002966
127 ACTIVATION OF MAPKK ACTIVITY 9 52 8.058e-05 0.002966
128 CELL PART MORPHOGENESIS 42 633 8.394e-05 0.003028
129 REGULATION OF BMP SIGNALING PATHWAY 11 77 8.372e-05 0.003028
130 PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 15 134 8.563e-05 0.003042
131 CELLULAR RESPONSE TO HORMONE STIMULUS 38 552 8.522e-05 0.003042
132 RESPONSE TO EXTERNAL STIMULUS 95 1821 8.986e-05 0.003167
133 CENTRAL NERVOUS SYSTEM PROJECTION NEURON AXONOGENESIS 6 22 9.052e-05 0.003167
134 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 60 1021 9.343e-05 0.003244
135 CARDIAC VENTRICLE DEVELOPMENT 13 106 9.869e-05 0.003402
136 REGULATION OF VASOCONSTRICTION 10 66 0.0001056 0.003599
137 INTRACELLULAR RECEPTOR SIGNALING PATHWAY 17 168 0.000106 0.003599
138 PALLIUM DEVELOPMENT 16 153 0.0001139 0.00384
139 VENOUS BLOOD VESSEL DEVELOPMENT 5 15 0.0001249 0.004182
140 RESPONSE TO NITROGEN COMPOUND 52 859 0.0001334 0.004433
141 ORGAN GROWTH 10 68 0.0001365 0.004505
142 EMBRYONIC ORGAN DEVELOPMENT 30 406 0.0001383 0.004533
143 REGULATION OF CELL DEATH 79 1472 0.000153 0.004979
144 IRON ION HOMEOSTASIS 10 69 0.0001547 0.004997
145 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 19 207 0.0001571 0.005043
146 REGULATION OF TRIGLYCERIDE METABOLIC PROCESS 7 34 0.000162 0.005094
147 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 24 296 0.0001603 0.005094
148 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 27 352 0.000161 0.005094
149 ACTIN FILAMENT BASED PROCESS 32 450 0.0001697 0.0053
150 ACTIVATION OF PROTEIN KINASE ACTIVITY 23 279 0.0001709 0.005303
151 REGULATION OF JNK CASCADE 16 159 0.0001787 0.005507
152 PHOSPHORYLATION 68 1228 0.0001867 0.005716
153 DEVELOPMENTAL MATURATION 18 193 0.0001901 0.005783
154 GLAND DEVELOPMENT 29 395 0.0001982 0.005989
155 CONNECTIVE TISSUE DEVELOPMENT 18 194 0.0002028 0.006088
156 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 45 724 0.0002106 0.006283
157 RESPONSE TO STEROID HORMONE 34 497 0.000223 0.006608
158 CELL MOTILITY 50 835 0.0002317 0.00678
159 LOCALIZATION OF CELL 50 835 0.0002317 0.00678
160 POSITIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 7 36 0.0002364 0.006874
161 CARTILAGE DEVELOPMENT 15 147 0.0002419 0.006926
162 MAMMARY GLAND ALVEOLUS DEVELOPMENT 5 17 0.0002426 0.006926
163 MAMMARY GLAND LOBULE DEVELOPMENT 5 17 0.0002426 0.006926
164 ENTRAINMENT OF CIRCADIAN CLOCK 6 26 0.0002474 0.006935
165 CYTOSKELETON DEPENDENT INTRACELLULAR TRANSPORT 13 116 0.0002467 0.006935
166 POSITIVE REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION 6 26 0.0002474 0.006935
167 ORGANELLE TRANSPORT ALONG MICROTUBULE 9 60 0.0002514 0.007005
168 DIGESTIVE SYSTEM DEVELOPMENT 15 148 0.0002606 0.007217
169 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 12 102 0.0002689 0.007403
170 CARDIAC MUSCLE CELL DIFFERENTIATION 10 74 0.0002787 0.007627
171 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 29 404 0.0002889 0.007862
172 REGULATION OF EPITHELIAL CELL MIGRATION 16 166 0.0002929 0.007878
173 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 16 166 0.0002929 0.007878
174 CELLULAR RESPONSE TO NITROGEN COMPOUND 34 505 0.0002991 0.007998
175 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 19 218 0.0003056 0.008086
176 NEGATIVE REGULATION OF CELL DIFFERENTIATION 39 609 0.0003059 0.008086
177 SKELETAL SYSTEM MORPHOGENESIS 18 201 0.0003139 0.008253
178 RESPONSE TO ABIOTIC STIMULUS 58 1024 0.0003176 0.008301
179 REGULATION OF SYSTEM PROCESS 34 507 0.0003214 0.008355
180 SMOOTH MUSCLE TISSUE DEVELOPMENT 5 18 0.0003262 0.008385
181 CENTROSOME LOCALIZATION 5 18 0.0003262 0.008385
182 ENDOTHELIUM DEVELOPMENT 11 90 0.0003435 0.008783
183 INTRINSIC APOPTOTIC SIGNALING PATHWAY 15 152 0.0003481 0.008802
184 ANGIOGENESIS 23 293 0.0003467 0.008802
185 POSITIVE REGULATION OF MAPK CASCADE 32 470 0.0003672 0.009235
186 CELLULAR TRANSITION METAL ION HOMEOSTASIS 10 77 0.0003868 0.009675
187 NEURON PROJECTION GUIDANCE 18 205 0.0003987 0.00992
188 REGULATION OF TRANSPORT 91 1804 0.0004009 0.009923
NumGOOverlapSizeP ValueAdj. P Value
1 ENZYME BINDING 115 1737 3.835e-11 3.563e-08
2 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 32 328 2.647e-07 0.000123
3 REGULATORY REGION NUCLEIC ACID BINDING 56 818 2.189e-06 0.000678
4 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 46 629 3.271e-06 0.0007597
5 MOLECULAR FUNCTION REGULATOR 80 1353 4.815e-06 0.0008946
6 UBIQUITIN LIKE PROTEIN TRANSFERASE ACTIVITY 34 420 7.75e-06 0.0012
7 CYTOSKELETAL PROTEIN BINDING 54 819 9.885e-06 0.001312
8 TRANSCRIPTION FACTOR BINDING 38 524 2.81e-05 0.003263
9 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 26 303 3.369e-05 0.003477
10 TRANSCRIPTION FACTOR ACTIVITY DIRECT LIGAND REGULATED SEQUENCE SPECIFIC DNA BINDING 9 48 4.17e-05 0.003874
11 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 69 1199 5.289e-05 0.004467
12 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 26 315 6.47e-05 0.004916
13 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 21 228 6.879e-05 0.004916
14 MAP KINASE KINASE KINASE ACTIVITY 6 22 9.052e-05 0.006007
15 KINASE ACTIVITY 51 842 0.0001525 0.008332
16 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 39 588 0.0001505 0.008332
17 GTPASE BINDING 24 295 0.0001522 0.008332
18 E BOX BINDING 7 34 0.000162 0.008363
19 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 20 226 0.0001749 0.008553
20 UBIQUITIN LIKE PROTEIN LIGASE BINDING 22 264 0.0002016 0.009364
21 STEROID HORMONE RECEPTOR ACTIVITY 9 59 0.0002206 0.009662
22 CALMODULIN BINDING 17 179 0.0002288 0.009662
NumGOOverlapSizeP ValueAdj. P Value
1 CYTOSKELETON 113 1967 1.756e-07 0.0001026
2 CELL LEADING EDGE 33 350 3.791e-07 0.0001107
3 MEMBRANE REGION 68 1134 1.666e-05 0.003243
4 AXON 31 418 0.0001007 0.009579
5 CELL PROJECTION 93 1786 0.0001148 0.009579
6 CUL3 RING UBIQUITIN LIGASE COMPLEX 10 64 8.081e-05 0.009579
7 AXON PART 20 219 0.0001142 0.009579

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Focal_adhesion_hsa04510 21 199 8.967e-06 0.0004663
2 MAPK_signaling_pathway_hsa04010 25 295 5.813e-05 0.001511
3 TNF_signaling_pathway_hsa04668 13 108 0.0001197 0.002075
4 PI3K_Akt_signaling_pathway_hsa04151 27 352 0.000161 0.002093
5 HIF_1_signaling_pathway_hsa04066 12 100 0.000223 0.002093
6 FoxO_signaling_pathway_hsa04068 14 132 0.0002585 0.002093
7 Gap_junction_hsa04540 11 88 0.0002818 0.002093
8 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 14 139 0.0004406 0.002693
9 Hippo_signaling_pathway_multiple_species_hsa04392 6 29 0.0004661 0.002693
10 p53_signaling_pathway_hsa04115 9 68 0.0006513 0.003233
11 Jak_STAT_signaling_pathway_hsa04630 15 162 0.0006839 0.003233
12 Hippo_signaling_pathway_hsa04390 14 154 0.001218 0.005276
13 Rap1_signaling_pathway_hsa04015 16 206 0.002918 0.01065
14 TGF_beta_signaling_pathway_hsa04350 9 84 0.002946 0.01065
15 Tight_junction_hsa04530 14 170 0.003074 0.01065
16 Oocyte_meiosis_hsa04114 11 124 0.004728 0.01537
17 Phospholipase_D_signaling_pathway_hsa04072 12 146 0.005985 0.01831
18 mTOR_signaling_pathway_hsa04150 12 151 0.007769 0.02244
19 Ras_signaling_pathway_hsa04014 16 232 0.009016 0.02451
20 Sphingolipid_signaling_pathway_hsa04071 10 118 0.009425 0.02451
21 ErbB_signaling_pathway_hsa04012 8 85 0.01066 0.02588
22 AMPK_signaling_pathway_hsa04152 10 121 0.01114 0.02588
23 cAMP_signaling_pathway_hsa04024 14 198 0.01145 0.02588
24 Cellular_senescence_hsa04218 12 160 0.01201 0.02601
25 Adherens_junction_hsa04520 7 72 0.01391 0.02893
26 Calcium_signaling_pathway_hsa04020 12 182 0.02966 0.05933
27 Regulation_of_actin_cytoskeleton_hsa04810 13 208 0.03531 0.06801
28 VEGF_signaling_pathway_hsa04370 5 59 0.05818 0.1081
29 cGMP_PKG_signaling_pathway_hsa04022 10 163 0.06614 0.1186
30 ECM_receptor_interaction_hsa04512 6 82 0.0716 0.1211
31 Lysosome_hsa04142 8 123 0.07222 0.1211
32 Hedgehog_signaling_pathway_hsa04340 4 47 0.08509 0.1361
33 Autophagy_animal_hsa04140 8 128 0.08637 0.1361
34 Endocytosis_hsa04144 13 244 0.0966 0.1477
35 Apoptosis_hsa04210 8 138 0.1192 0.1768
36 NF_kappa_B_signaling_pathway_hsa04064 6 95 0.1224 0.1768
37 Wnt_signaling_pathway_hsa04310 8 146 0.1495 0.2101
38 Cytokine_cytokine_receptor_interaction_hsa04060 13 270 0.1668 0.2254
39 Ferroptosis_hsa04216 3 40 0.1691 0.2254
40 Mitophagy_animal_hsa04137 4 65 0.2 0.26
41 Cell_adhesion_molecules_.CAMs._hsa04514 7 145 0.2579 0.3272
42 Phosphatidylinositol_signaling_system_hsa04070 5 99 0.2763 0.3377
43 Cell_cycle_hsa04110 6 124 0.2793 0.3377
44 Apoptosis_multiple_species_hsa04215 2 33 0.3288 0.3886
45 Necroptosis_hsa04217 7 164 0.3658 0.4227
46 Notch_signaling_pathway_hsa04330 2 48 0.513 0.5799
47 Apelin_signaling_pathway_hsa04371 5 137 0.5398 0.5973
48 Phagosome_hsa04145 5 152 0.6322 0.6849
49 Peroxisome_hsa04146 2 83 0.7994 0.8483
50 Neuroactive_ligand_receptor_interaction_hsa04080 5 278 0.9714 1

Quest ID: 90f89666d83fbd33fe226733173a6a54