Explanation
This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are
presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.
"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.
miRNA-gene regulations
| Num | microRNA | Gene | miRNA log2FC | miRNA pvalue | Gene log2FC | Gene pvalue | Interaction | Correlation beta | Correlation P-value | PMID | Reported in cancer studies |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | hsa-miR-106a-5p | AKT3 | 3.99 | 0 | -3.33 | 1.0E-5 | miRNATAP | -0.12 | 0.02117 | NA | |
| 2 | hsa-miR-106b-5p | AKT3 | 2.81 | 0 | -3.33 | 1.0E-5 | miRNATAP | -0.41 | 1.0E-5 | NA | |
| 3 | hsa-miR-142-3p | AKT3 | 4.35 | 0 | -3.33 | 1.0E-5 | miRanda | -0.16 | 0.00934 | NA | |
| 4 | hsa-miR-15a-5p | AKT3 | 2.05 | 0 | -3.33 | 1.0E-5 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.37 | 0.00021 | NA | |
| 5 | hsa-miR-15b-5p | AKT3 | 3.32 | 0 | -3.33 | 1.0E-5 | miRNATAP | -0.25 | 0.00571 | NA | |
| 6 | hsa-miR-16-5p | AKT3 | 2.94 | 0 | -3.33 | 1.0E-5 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.31 | 0.00086 | NA | |
| 7 | hsa-miR-17-5p | AKT3 | 2.33 | 2.0E-5 | -3.33 | 1.0E-5 | TargetScan; miRNATAP | -0.17 | 0.02914 | NA | |
| 8 | hsa-miR-29b-2-5p | AKT3 | -0.6 | 0.18954 | -3.33 | 1.0E-5 | mirMAP | -0.23 | 0.01747 | NA | |
| 9 | hsa-miR-29b-3p | AKT3 | 0.67 | 0.23406 | -3.33 | 1.0E-5 | miRNATAP | -0.28 | 0.00031 | 26512921 | MicroRNA 29B mir 29b regulates the Warburg effect in ovarian cancer by targeting AKT2 and AKT3 |
| 10 | hsa-miR-3065-5p | AKT3 | 2.14 | 0.06094 | -3.33 | 1.0E-5 | mirMAP | -0.22 | 0 | NA | |
| 11 | hsa-miR-362-3p | AKT3 | 0.68 | 0.22615 | -3.33 | 1.0E-5 | miRanda | -0.25 | 0.00124 | NA | |
| 12 | hsa-miR-501-3p | AKT3 | 1.72 | 0.00759 | -3.33 | 1.0E-5 | miRNATAP | -0.18 | 0.00733 | NA | |
| 13 | hsa-miR-502-3p | AKT3 | -0.1 | 0.80889 | -3.33 | 1.0E-5 | miRNATAP | -0.23 | 0.03065 | NA | |
| 14 | hsa-miR-93-5p | AKT3 | 2.66 | 0 | -3.33 | 1.0E-5 | miRNATAP | -0.33 | 0.00021 | NA | |
| 15 | hsa-let-7a-5p | BCL2L1 | 0.15 | 0.64531 | 0.39 | 0.37256 | TargetScan; miRNATAP | -0.2 | 0.01274 | 26915294; 20347499 | As a result transcript levels of the tumor-suppressive miR-15 and let-7 families increased which targeted and decreased the expression of the crucial prosurvival genes BCL-2 and BCL-XL respectively;The let 7 family of microRNAs inhibits Bcl xL expression and potentiates sorafenib induced apoptosis in human hepatocellular carcinoma; The effect of let-7 on Bcl-xL expression was examined by Western blot and a reporter assay; Microarray analysis followed by in silico target prediction identified let-7 microRNAs as being downregulated in Huh7 hepatoma cells in comparison with primary human hepatocytes as well as possessing a putative target site in the bcl-xl mRNA |
| 16 | hsa-miR-23b-3p | BCL2L1 | -0.58 | 0.19048 | 0.39 | 0.37256 | miRNAWalker2 validate | -0.11 | 0.04171 | NA | |
| 17 | hsa-miR-342-3p | BCL2L1 | 1.31 | 0.02072 | 0.39 | 0.37256 | PITA; miRanda; miRNATAP | -0.13 | 0.00344 | NA | |
| 18 | hsa-miR-342-5p | BCL2L1 | 1.39 | 0.01536 | 0.39 | 0.37256 | miRNATAP | -0.1 | 0.01901 | NA | |
| 19 | hsa-let-7d-5p | CBL | 0.83 | 0.0127 | -0.22 | 0.60145 | MirTarget | -0.21 | 0.0047 | NA | |
| 20 | hsa-miR-141-5p | CBL | 7.14 | 0 | -0.22 | 0.60145 | mirMAP | -0.12 | 0.0004 | NA | |
| 21 | hsa-miR-200c-3p | CBL | 6.47 | 0 | -0.22 | 0.60145 | MirTarget; mirMAP | -0.1 | 0.00481 | NA | |
| 22 | hsa-miR-21-3p | CBL | 3.5 | 0 | -0.22 | 0.60145 | MirTarget; mirMAP | -0.11 | 0.01028 | NA | |
| 23 | hsa-miR-29c-3p | CBL | -0.41 | 0.52934 | -0.22 | 0.60145 | mirMAP | -0.12 | 0.00078 | NA | |
| 24 | hsa-miR-30e-3p | CBL | -0.04 | 0.93258 | -0.22 | 0.60145 | MirTarget | -0.22 | 0.00015 | NA | |
| 25 | hsa-miR-374a-3p | CBL | 0.47 | 0.30527 | -0.22 | 0.60145 | mirMAP | -0.18 | 0.00096 | NA | |
| 26 | hsa-miR-374b-5p | CBL | -0.11 | 0.76489 | -0.22 | 0.60145 | mirMAP | -0.14 | 0.02756 | NA | |
| 27 | hsa-miR-3913-5p | CBL | 0.15 | 0.73484 | -0.22 | 0.60145 | MirTarget; miRNATAP | -0.17 | 0.00253 | NA | |
| 28 | hsa-miR-664a-3p | CBL | 0.25 | 0.56171 | -0.22 | 0.60145 | mirMAP | -0.13 | 0.02466 | NA | |
| 29 | hsa-miR-7-1-3p | CBL | 1.43 | 0.00471 | -0.22 | 0.60145 | mirMAP | -0.1 | 0.0286 | NA | |
| 30 | hsa-miR-222-5p | CBLB | 2.52 | 0.00142 | -0.06 | 0.89329 | MirTarget | -0.1 | 0.00159 | NA | |
| 31 | hsa-let-7a-5p | CCND1 | 0.15 | 0.64531 | 0.15 | 0.87753 | TargetScan; miRNATAP | -0.54 | 0.00245 | NA | |
| 32 | hsa-let-7b-5p | CCND1 | -0.19 | 0.65188 | 0.15 | 0.87753 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.33 | 0.01459 | 18379589; 23162627 | The effect of let-7b on protein expression was due to targeting of 3'-untranslated regions 3'UTRs of individual mRNAs as exemplified by reporter gene analyses for cyclin D1;Cyclin D1 expression was significantly higher in cells transfected with let-7b plasmid and let-7b inhibitor compared with control cells P<0.05 |
| 33 | hsa-miR-106a-5p | CCND1 | 3.99 | 0 | 0.15 | 0.87753 | MirTarget; miRNATAP | -0.43 | 0 | NA | |
| 34 | hsa-miR-15a-5p | CCND1 | 2.05 | 0 | 0.15 | 0.87753 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.35 | 0.00776 | 22922827 | CCND1 has been found to be a target of miR-15a and miR-16-1 through analysis of complementary sequences between microRNAs and CCND1 mRNA; Moreover the transcription of CCND1 is suppressed by miR-15a and miR-16-1 via direct binding to the CCND1 3'-untranslated region 3'-UTR |
| 35 | hsa-miR-15b-5p | CCND1 | 3.32 | 0 | 0.15 | 0.87753 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.42 | 0.00029 | NA | |
| 36 | hsa-miR-16-1-3p | CCND1 | 2.83 | 0 | 0.15 | 0.87753 | miRNAWalker2 validate; miRTarBase | -0.28 | 0.01458 | 22922827; 18483394 | CCND1 has been found to be a target of miR-15a and miR-16-1 through analysis of complementary sequences between microRNAs and CCND1 mRNA; Moreover the transcription of CCND1 is suppressed by miR-15a and miR-16-1 via direct binding to the CCND1 3'-untranslated region 3'-UTR;Truncation in CCND1 mRNA alters miR 16 1 regulation in mantle cell lymphoma; Furthermore we demonstrated that this truncation alters miR-16-1 binding sites and through the use of reporter constructs we were able to show that miR-16-1 regulates CCND1 mRNA expression; This study introduces the role of miR-16-1 in the regulation of CCND1 in MCL |
| 37 | hsa-miR-16-5p | CCND1 | 2.94 | 0 | 0.15 | 0.87753 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.28 | 0.01688 | 23991964; 22922827; 18483394 | At the molecular level our results further revealed that cyclin D1 expression was negatively regulated by miR-16;CCND1 has been found to be a target of miR-15a and miR-16-1 through analysis of complementary sequences between microRNAs and CCND1 mRNA; Moreover the transcription of CCND1 is suppressed by miR-15a and miR-16-1 via direct binding to the CCND1 3'-untranslated region 3'-UTR;Truncation in CCND1 mRNA alters miR 16 1 regulation in mantle cell lymphoma; Furthermore we demonstrated that this truncation alters miR-16-1 binding sites and through the use of reporter constructs we were able to show that miR-16-1 regulates CCND1 mRNA expression; This study introduces the role of miR-16-1 in the regulation of CCND1 in MCL |
| 38 | hsa-miR-195-5p | CCND1 | -1.59 | 0.01691 | 0.15 | 0.87753 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.18 | 0.03327 | 26631043; 21350001; 25823925 | MiR 195 inhibits the proliferation of human cervical cancer cells by directly targeting cyclin D1; The present study was to evaluate the level of miR-195 and cyclin D1 in CC tissues and cells; We further investigated the molecular mechanisms of miR-195 and cyclin D1 in CC cell lines HeLa and SiHa; Furthermore the expression of miR-195 was inversely proportional to that of cyclin D1 mRNA or protein p = 0.013 p = 0.015 respectively; However the inhibitor of miR-195 promoted the expression of cyclin D1 and cell proliferation; In conclusion our data suggest that miR-195 may have the potential role in treatment of CC patients as well as miR-195 is a novel regulator of invasiveness and tumorigenicity in CC cells by targeting cyclin D1;Raf-1 and Ccnd1 were identified as novel direct targets of miR-195 and miR-497 miR-195/497 expression levels in clinical specimens were found to be correlated inversely with malignancy of breast cancer;MicroRNA profiling identifies MiR 195 suppresses osteosarcoma cell metastasis by targeting CCND1; Meanwhile CCND1 was identified as the target gene of miR-195 and further studied; More importantly using real-time PCR we evaluated the expression of miR-195 and CCND1 in osteosarcoma samples from 107 frozen biopsy tissues and 99 formalin- or paraformalin-fixed paraffin-embedded FFPE tissues; Results indicated lowly expressed miR-195 or highly CCND1 correlated with positive overall survival and their expression inversely related to each other; In summary our study suggests miR-195 functions as a tumor metastasis suppressor gene by down-regulating CCND1 and can be used as a potential target in the treatment of osteosarcoma |
| 39 | hsa-miR-20b-5p | CCND1 | 4.57 | 5.0E-5 | 0.15 | 0.87753 | MirTarget; miRNATAP | -0.31 | 0 | NA | |
| 40 | hsa-miR-34a-5p | CCND1 | 0.83 | 0.04775 | 0.15 | 0.87753 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.42 | 0.00174 | 25792709; 21399894 | This inhibition of proliferation was associated with a decrease in cyclin D1 levels orchestrated principally by HNF-4α a target of miR-34a considered to act as a tumour suppressor in the liver;Quantitative PCR and western analysis confirmed decreased expression of two genes BCL-2 and CCND1 in docetaxel-resistant cells which are both targeted by miR-34a |
| 41 | hsa-miR-497-5p | CCND1 | -1.44 | 0.02251 | 0.15 | 0.87753 | MirTarget; miRNATAP | -0.25 | 0.00498 | 21350001 | Raf-1 and Ccnd1 were identified as novel direct targets of miR-195 and miR-497 miR-195/497 expression levels in clinical specimens were found to be correlated inversely with malignancy of breast cancer |
| 42 | hsa-let-7b-5p | CCND2 | -0.19 | 0.65188 | -2.81 | 0.0014 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.27 | 0.02622 | NA | |
| 43 | hsa-miR-106a-5p | CCND2 | 3.99 | 0 | -2.81 | 0.0014 | miRNATAP | -0.44 | 0 | NA | |
| 44 | hsa-miR-106b-5p | CCND2 | 2.81 | 0 | -2.81 | 0.0014 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.31 | 0.00374 | NA | |
| 45 | hsa-miR-10a-3p | CCND2 | 0.97 | 0.31667 | -2.81 | 0.0014 | mirMAP | -0.2 | 0.00011 | NA | |
| 46 | hsa-miR-130b-5p | CCND2 | 3.74 | 0 | -2.81 | 0.0014 | mirMAP | -0.46 | 0 | NA | |
| 47 | hsa-miR-141-3p | CCND2 | 7.3 | 0 | -2.81 | 0.0014 | MirTarget; TargetScan | -0.24 | 0.00021 | NA | |
| 48 | hsa-miR-151a-3p | CCND2 | 0.37 | 0.37692 | -2.81 | 0.0014 | mirMAP | -0.25 | 0.03818 | NA | |
| 49 | hsa-miR-15a-5p | CCND2 | 2.05 | 0 | -2.81 | 0.0014 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.27 | 0.02193 | NA | |
| 50 | hsa-miR-15b-5p | CCND2 | 3.32 | 0 | -2.81 | 0.0014 | miRNATAP | -0.53 | 0 | NA | |
| 51 | hsa-miR-16-2-3p | CCND2 | 3.8 | 0 | -2.81 | 0.0014 | mirMAP | -0.29 | 0.00207 | NA | |
| 52 | hsa-miR-16-5p | CCND2 | 2.94 | 0 | -2.81 | 0.0014 | miRNAWalker2 validate; miRNATAP | -0.25 | 0.01827 | NA | |
| 53 | hsa-miR-182-5p | CCND2 | 5.87 | 0 | -2.81 | 0.0014 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.28 | 2.0E-5 | NA | |
| 54 | hsa-miR-183-5p | CCND2 | 6.62 | 0 | -2.81 | 0.0014 | miRNATAP | -0.29 | 0 | NA | |
| 55 | hsa-miR-191-5p | CCND2 | 1.59 | 0.00074 | -2.81 | 0.0014 | MirTarget | -0.32 | 0.00314 | NA | |
| 56 | hsa-miR-200a-3p | CCND2 | 6.34 | 0 | -2.81 | 0.0014 | MirTarget | -0.41 | 0 | NA | |
| 57 | hsa-miR-20b-5p | CCND2 | 4.57 | 5.0E-5 | -2.81 | 0.0014 | miRNATAP | -0.3 | 0 | NA | |
| 58 | hsa-miR-224-3p | CCND2 | 2.85 | 0.00018 | -2.81 | 0.0014 | mirMAP | -0.22 | 0.00101 | NA | |
| 59 | hsa-miR-28-5p | CCND2 | -0.82 | 0.02212 | -2.81 | 0.0014 | miRanda | -0.43 | 0.00273 | NA | |
| 60 | hsa-miR-3065-3p | CCND2 | 1.89 | 0.03082 | -2.81 | 0.0014 | MirTarget; miRNATAP | -0.21 | 0.00027 | NA | |
| 61 | hsa-miR-3065-5p | CCND2 | 2.14 | 0.06094 | -2.81 | 0.0014 | mirMAP | -0.2 | 0.00026 | NA | |
| 62 | hsa-miR-30d-3p | CCND2 | -0.07 | 0.85742 | -2.81 | 0.0014 | mirMAP | -0.55 | 1.0E-5 | NA | |
| 63 | hsa-miR-324-3p | CCND2 | 1.51 | 0.00384 | -2.81 | 0.0014 | miRNAWalker2 validate | -0.44 | 0 | NA | |
| 64 | hsa-miR-33a-3p | CCND2 | 2.06 | 0.00156 | -2.81 | 0.0014 | MirTarget | -0.27 | 0.00041 | NA | |
| 65 | hsa-miR-3607-3p | CCND2 | 1.38 | 0.02401 | -2.81 | 0.0014 | mirMAP | -0.19 | 0.0234 | NA | |
| 66 | hsa-miR-378a-3p | CCND2 | 1.47 | 0.04667 | -2.81 | 0.0014 | miRNAWalker2 validate | -0.19 | 0.00601 | NA | |
| 67 | hsa-miR-429 | CCND2 | 6.4 | 0 | -2.81 | 0.0014 | miRNATAP | -0.46 | 0 | NA | |
| 68 | hsa-miR-497-5p | CCND2 | -1.44 | 0.02251 | -2.81 | 0.0014 | MirTarget; miRNATAP | -0.27 | 0.00058 | NA | |
| 69 | hsa-miR-501-5p | CCND2 | 1.04 | 0.07772 | -2.81 | 0.0014 | PITA; mirMAP; miRNATAP | -0.17 | 0.04875 | NA | |
| 70 | hsa-miR-550a-5p | CCND2 | 1.22 | 0.06138 | -2.81 | 0.0014 | MirTarget | -0.22 | 0.00363 | NA | |
| 71 | hsa-miR-660-5p | CCND2 | -0.07 | 0.88525 | -2.81 | 0.0014 | mirMAP | -0.29 | 0.00793 | NA | |
| 72 | hsa-miR-9-3p | CCND2 | 1.69 | 0.12517 | -2.81 | 0.0014 | MirTarget; mirMAP; miRNATAP | -0.14 | 0.00185 | NA | |
| 73 | hsa-miR-93-5p | CCND2 | 2.66 | 0 | -2.81 | 0.0014 | miRNATAP | -0.48 | 0 | NA | |
| 74 | hsa-miR-96-5p | CCND2 | 5.63 | 0 | -2.81 | 0.0014 | TargetScan; miRNATAP | -0.24 | 0.0003 | NA | |
| 75 | hsa-miR-27b-3p | CCND3 | -0.09 | 0.85847 | -0.54 | 0.12437 | miRNAWalker2 validate | -0.14 | 0.00019 | NA | |
| 76 | hsa-miR-429 | CCND3 | 6.4 | 0 | -0.54 | 0.12437 | miRNATAP | -0.11 | 1.0E-5 | NA | |
| 77 | hsa-miR-96-5p | CCND3 | 5.63 | 0 | -0.54 | 0.12437 | TargetScan | -0.12 | 1.0E-5 | NA | |
| 78 | hsa-miR-103a-3p | CD274 | 0.99 | 0.00468 | 2.22 | 0.05161 | miRNAWalker2 validate | -0.48 | 0.01013 | NA | |
| 79 | hsa-miR-106a-5p | CD274 | 3.99 | 0 | 2.22 | 0.05161 | MirTarget; miRNATAP | -0.24 | 0.00245 | NA | |
| 80 | hsa-miR-182-5p | CD274 | 5.87 | 0 | 2.22 | 0.05161 | mirMAP | -0.34 | 5.0E-5 | NA | |
| 81 | hsa-miR-200a-3p | CD274 | 6.34 | 0 | 2.22 | 0.05161 | MirTarget | -0.35 | 1.0E-5 | NA | |
| 82 | hsa-miR-20b-5p | CD274 | 4.57 | 5.0E-5 | 2.22 | 0.05161 | MirTarget; miRNATAP | -0.19 | 0.0007 | 24468585 | These findings suggest that miR-20b -21 and -130b up-regulated in colorectal cancer through inhibiting the expression of PTEN result in B7-H1 over-expression in colorectal cancer |
| 83 | hsa-miR-324-5p | CD274 | 1.31 | 0.01168 | 2.22 | 0.05161 | miRanda | -0.47 | 0.00014 | NA | |
| 84 | hsa-miR-429 | CD274 | 6.4 | 0 | 2.22 | 0.05161 | miRanda | -0.41 | 0 | NA | |
| 85 | hsa-miR-497-5p | CD274 | -1.44 | 0.02251 | 2.22 | 0.05161 | MirTarget | -0.38 | 0.00018 | NA | |
| 86 | hsa-miR-93-5p | CD274 | 2.66 | 0 | 2.22 | 0.05161 | MirTarget; miRNATAP | -0.46 | 0.00064 | NA | |
| 87 | hsa-miR-24-3p | CISH | 1.56 | 0.00052 | -0.89 | 0.10733 | MirTarget | -0.25 | 0.00041 | NA | |
| 88 | hsa-miR-324-5p | CISH | 1.31 | 0.01168 | -0.89 | 0.10733 | miRanda | -0.2 | 0.0012 | NA | |
| 89 | hsa-miR-200b-3p | CNTFR | 5.56 | 0 | -4.16 | 0.0243 | TargetScan | -0.44 | 0.00218 | NA | |
| 90 | hsa-miR-200c-3p | CNTFR | 6.47 | 0 | -4.16 | 0.0243 | miRNATAP | -0.62 | 9.0E-5 | NA | |
| 91 | hsa-miR-21-5p | CNTFR | 2.65 | 0 | -4.16 | 0.0243 | miRNATAP | -0.95 | 0.00229 | NA | |
| 92 | hsa-miR-429 | CNTFR | 6.4 | 0 | -4.16 | 0.0243 | PITA; miRanda; miRNATAP | -0.37 | 0.00625 | NA | |
| 93 | hsa-miR-589-5p | CNTFR | 1.56 | 0.00033 | -4.16 | 0.0243 | miRNATAP | -0.63 | 0.00999 | NA | |
| 94 | hsa-miR-21-3p | CREBBP | 3.5 | 0 | -0.4 | 0.18067 | MirTarget | -0.14 | 0 | NA | |
| 95 | hsa-miR-590-3p | CREBBP | 2.35 | 0 | -0.4 | 0.18067 | PITA; miRanda; mirMAP; miRNATAP | -0.1 | 0.00219 | NA | |
| 96 | hsa-miR-217 | CSF2RA | -0.38 | 0.71741 | 1.05 | 0.28308 | miRanda | -0.23 | 1.0E-5 | NA | |
| 97 | hsa-miR-429 | CSF2RA | 6.4 | 0 | 1.05 | 0.28308 | miRanda | -0.22 | 0.00182 | NA | |
| 98 | hsa-miR-15b-3p | CSF2RB | 3.58 | 0 | -0.53 | 0.5247 | mirMAP | -0.24 | 0.00379 | NA | |
| 99 | hsa-miR-19b-3p | CSF2RB | 1.68 | 0.00086 | -0.53 | 0.5247 | MirTarget | -0.25 | 0.00793 | NA | |
| 100 | hsa-miR-30b-3p | CSF2RB | 0.17 | 0.76608 | -0.53 | 0.5247 | MirTarget | -0.28 | 0.00087 | NA | |
| 101 | hsa-miR-532-5p | CSF2RB | -0.3 | 0.50393 | -0.53 | 0.5247 | MirTarget | -0.22 | 0.0443 | NA | |
| 102 | hsa-miR-30b-3p | CSF3R | 0.17 | 0.76608 | 0.32 | 0.72354 | MirTarget | -0.25 | 0.00528 | NA | |
| 103 | hsa-miR-361-5p | CSF3R | 0.01 | 0.9852 | 0.32 | 0.72354 | miRanda | -0.61 | 3.0E-5 | NA | |
| 104 | hsa-miR-429 | CSF3R | 6.4 | 0 | 0.32 | 0.72354 | miRanda | -0.2 | 0.00181 | NA | |
| 105 | hsa-miR-940 | CSF3R | 3.78 | 5.0E-5 | 0.32 | 0.72354 | MirTarget | -0.13 | 0.04993 | NA | |
| 106 | hsa-miR-185-5p | CTF1 | 2.47 | 0 | -2.6 | 0.00053 | MirTarget | -0.41 | 1.0E-5 | NA | |
| 107 | hsa-miR-342-3p | CTF1 | 1.31 | 0.02072 | -2.6 | 0.00053 | miRanda | -0.23 | 0.00232 | NA | |
| 108 | hsa-miR-148a-3p | EP300 | 1.1 | 0.05204 | 0.22 | 0.57893 | miRNATAP | -0.1 | 0.00975 | NA | |
| 109 | hsa-miR-26b-5p | EP300 | 0.31 | 0.46163 | 0.22 | 0.57893 | miRNAWalker2 validate; miRNATAP | -0.13 | 0.01396 | NA | |
| 110 | hsa-miR-30c-5p | EP300 | 0.39 | 0.34861 | 0.22 | 0.57893 | miRNAWalker2 validate | -0.19 | 0.0009 | NA | |
| 111 | hsa-miR-339-5p | EP300 | 1.23 | 0.03075 | 0.22 | 0.57893 | miRanda | -0.2 | 0 | NA | |
| 112 | hsa-miR-342-3p | EP300 | 1.31 | 0.02072 | 0.22 | 0.57893 | MirTarget; PITA; miRanda; miRNATAP | -0.12 | 0.00407 | NA | |
| 113 | hsa-miR-361-3p | EP300 | 0.81 | 0.04185 | 0.22 | 0.57893 | PITA | -0.14 | 0.02008 | NA | |
| 114 | hsa-miR-374b-5p | EP300 | -0.11 | 0.76489 | 0.22 | 0.57893 | mirMAP; miRNATAP | -0.16 | 0.00856 | NA | |
| 115 | hsa-miR-590-3p | EP300 | 2.35 | 0 | 0.22 | 0.57893 | MirTarget; PITA; miRanda; mirMAP; miRNATAP | -0.14 | 0.00229 | NA | |
| 116 | hsa-miR-127-3p | EPOR | -1.38 | 0.0732 | -0.15 | 0.84806 | miRanda | -0.13 | 0.02083 | NA | |
| 117 | hsa-miR-15a-5p | GHR | 2.05 | 0 | -3.3 | 0.01335 | MirTarget; miRNATAP | -0.68 | 9.0E-5 | NA | |
| 118 | hsa-miR-15b-5p | GHR | 3.32 | 0 | -3.3 | 0.01335 | MirTarget; miRNATAP | -0.52 | 0.00106 | NA | |
| 119 | hsa-miR-16-2-3p | GHR | 3.8 | 0 | -3.3 | 0.01335 | mirMAP | -0.5 | 0.00041 | NA | |
| 120 | hsa-miR-16-5p | GHR | 2.94 | 0 | -3.3 | 0.01335 | MirTarget; miRNATAP | -0.56 | 0.00046 | NA | |
| 121 | hsa-miR-3065-5p | GHR | 2.14 | 0.06094 | -3.3 | 0.01335 | MirTarget | -0.38 | 0 | NA | |
| 122 | hsa-miR-338-5p | GHR | -0.11 | 0.89468 | -3.3 | 0.01335 | PITA | -0.5 | 0 | NA | |
| 123 | hsa-miR-429 | GHR | 6.4 | 0 | -3.3 | 0.01335 | miRanda; miRNATAP | -0.24 | 0.01323 | NA | |
| 124 | hsa-miR-590-3p | GHR | 2.35 | 0 | -3.3 | 0.01335 | mirMAP | -0.3 | 0.04853 | NA | |
| 125 | hsa-miR-7-1-3p | GHR | 1.43 | 0.00471 | -3.3 | 0.01335 | MirTarget; mirMAP | -0.41 | 0.00648 | NA | |
| 126 | hsa-miR-106b-5p | IFNAR2 | 2.81 | 0 | -0.05 | 0.87658 | miRNAWalker2 validate | -0.1 | 0.01118 | NA | |
| 127 | hsa-miR-1271-5p | IFNAR2 | 0.21 | 0.74254 | -0.05 | 0.87658 | mirMAP | -0.13 | 2.0E-5 | NA | |
| 128 | hsa-miR-508-3p | IFNE | 0.98 | 0.43953 | 4.56 | 0.00032 | MirTarget | -0.17 | 0.00391 | NA | |
| 129 | hsa-miR-125a-5p | IFNG | -1.32 | 0.00714 | 3.94 | 0.0051 | miRanda | -0.64 | 9.0E-5 | NA | |
| 130 | hsa-miR-369-3p | IFNG | 0.37 | 0.63876 | 3.94 | 0.0051 | PITA; miRNATAP | -0.31 | 0.00283 | NA | |
| 131 | hsa-miR-409-3p | IFNG | 0.29 | 0.67815 | 3.94 | 0.0051 | miRNAWalker2 validate | -0.43 | 0.00012 | NA | |
| 132 | hsa-miR-429 | IFNG | 6.4 | 0 | 3.94 | 0.0051 | miRanda | -0.3 | 0.00378 | NA | |
| 133 | hsa-miR-362-3p | IFNGR1 | 0.68 | 0.22615 | 0.12 | 0.78871 | miRanda | -0.12 | 0.00701 | NA | |
| 134 | hsa-miR-429 | IFNGR1 | 6.4 | 0 | 0.12 | 0.78871 | miRNATAP | -0.13 | 3.0E-5 | NA | |
| 135 | hsa-miR-375 | IFNK | 3.38 | 0.04499 | 1.68 | 0.22278 | miRanda | -0.18 | 0.0001 | NA | |
| 136 | hsa-miR-106a-5p | IL10 | 3.99 | 0 | 2.55 | 0.00205 | miRNAWalker2 validate | -0.17 | 0.00228 | NA | |
| 137 | hsa-miR-361-5p | IL10 | 0.01 | 0.9852 | 2.55 | 0.00205 | MirTarget; PITA; miRanda; miRNATAP | -0.37 | 0.0076 | NA | |
| 138 | hsa-miR-125a-5p | IL10RA | -1.32 | 0.00714 | 0.1 | 0.89911 | miRanda | -0.2 | 0.02715 | NA | |
| 139 | hsa-miR-421 | IL10RA | 1.98 | 0.00092 | 0.1 | 0.89911 | miRanda | -0.15 | 0.03978 | NA | |
| 140 | hsa-miR-3607-3p | IL11 | 1.38 | 0.02401 | 2.82 | 0.01391 | MirTarget | -0.37 | 0.00053 | NA | |
| 141 | hsa-miR-330-5p | IL11RA | 2.25 | 0.00028 | -2.49 | 1.0E-5 | miRanda | -0.23 | 1.0E-5 | NA | |
| 142 | hsa-miR-139-5p | IL12A | -2.09 | 0.00038 | 1.74 | 0.13678 | miRanda | -0.23 | 0.04417 | NA | |
| 143 | hsa-miR-9-5p | IL12A | 1.8 | 0.14527 | 1.74 | 0.13678 | MirTarget | -0.11 | 0.03925 | NA | |
| 144 | hsa-miR-217 | IL12RB1 | -0.38 | 0.71741 | 1.63 | 0.096 | miRanda | -0.15 | 0.00464 | NA | |
| 145 | hsa-miR-125a-3p | IL12RB2 | -0.07 | 0.92074 | 4.35 | 0.00344 | miRanda | -0.28 | 0.012 | NA | |
| 146 | hsa-miR-125a-5p | IL12RB2 | -1.32 | 0.00714 | 4.35 | 0.00344 | miRanda | -1.12 | 0 | NA | |
| 147 | hsa-miR-129-5p | IL12RB2 | -2.67 | 0.00696 | 4.35 | 0.00344 | miRanda | -0.32 | 0.00017 | NA | |
| 148 | hsa-miR-199a-5p | IL12RB2 | -1.25 | 0.07478 | 4.35 | 0.00344 | miRanda | -0.31 | 0.01135 | NA | |
| 149 | hsa-miR-28-5p | IL12RB2 | -0.82 | 0.02212 | 4.35 | 0.00344 | miRanda | -0.87 | 0.0003 | NA | |
| 150 | hsa-miR-338-3p | IL12RB2 | 0.45 | 0.55849 | 4.35 | 0.00344 | miRanda | -0.61 | 0 | NA |
| Num | GO | Overlap | Size | P Value | Adj. P Value |
|---|---|---|---|---|---|
| 1 | CYTOKINE MEDIATED SIGNALING PATHWAY | 51 | 452 | 3.208e-59 | 1.493e-55 |
| 2 | RESPONSE TO CYTOKINE | 56 | 714 | 8.764e-57 | 2.039e-53 |
| 3 | CELLULAR RESPONSE TO CYTOKINE STIMULUS | 52 | 606 | 3.657e-54 | 5.672e-51 |
| 4 | CELLULAR RESPONSE TO ORGANIC SUBSTANCE | 69 | 1848 | 5.448e-51 | 6.337e-48 |
| 5 | REGULATION OF JAK STAT CASCADE | 26 | 144 | 1.323e-34 | 1.026e-31 |
| 6 | REGULATION OF STAT CASCADE | 26 | 144 | 1.323e-34 | 1.026e-31 |
| 7 | REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION | 49 | 1656 | 1.839e-28 | 1.222e-25 |
| 8 | STAT CASCADE | 17 | 50 | 5.023e-28 | 2.597e-25 |
| 9 | JAK STAT CASCADE | 17 | 50 | 5.023e-28 | 2.597e-25 |
| 10 | POSITIVE REGULATION OF STAT CASCADE | 18 | 73 | 9.994e-27 | 4.227e-24 |
| 11 | POSITIVE REGULATION OF JAK STAT CASCADE | 18 | 73 | 9.994e-27 | 4.227e-24 |
| 12 | POSITIVE REGULATION OF RESPONSE TO STIMULUS | 48 | 1929 | 1.909e-24 | 7.403e-22 |
| 13 | REGULATION OF PHOSPHORUS METABOLIC PROCESS | 44 | 1618 | 1.258e-23 | 4.504e-21 |
| 14 | REGULATION OF TYROSINE PHOSPHORYLATION OF STAT PROTEIN | 16 | 68 | 1.789e-23 | 5.944e-21 |
| 15 | REGULATION OF TYROSINE PHOSPHORYLATION OF STAT3 PROTEIN | 14 | 44 | 9.571e-23 | 2.969e-20 |
| 16 | IMMUNE SYSTEM PROCESS | 46 | 1984 | 5.669e-22 | 1.649e-19 |
| 17 | POSITIVE REGULATION OF TYROSINE PHOSPHORYLATION OF STAT3 PROTEIN | 13 | 37 | 7.48e-22 | 2.047e-19 |
| 18 | REGULATION OF PROTEIN MODIFICATION PROCESS | 43 | 1710 | 1.1e-21 | 2.843e-19 |
| 19 | POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION | 33 | 876 | 1.579e-21 | 3.868e-19 |
| 20 | REGULATION OF IMMUNE SYSTEM PROCESS | 39 | 1403 | 5.699e-21 | 1.326e-18 |
| 21 | REGULATION OF IMMUNE RESPONSE | 32 | 858 | 1.025e-20 | 2.272e-18 |
| 22 | REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION | 19 | 213 | 2.622e-19 | 5.547e-17 |
| 23 | INTRACELLULAR SIGNAL TRANSDUCTION | 39 | 1572 | 3.13e-19 | 6.331e-17 |
| 24 | LYMPHOCYTE ACTIVATION | 22 | 342 | 3.522e-19 | 6.828e-17 |
| 25 | REGULATION OF CELL PROLIFERATION | 38 | 1496 | 4.881e-19 | 9.085e-17 |
| 26 | CELL ACTIVATION | 26 | 568 | 6.239e-19 | 1.117e-16 |
| 27 | REGULATION OF HOMOTYPIC CELL CELL ADHESION | 21 | 307 | 7.082e-19 | 1.22e-16 |
| 28 | REGULATION OF CELL CELL ADHESION | 22 | 380 | 3.359e-18 | 5.582e-16 |
| 29 | POSITIVE REGULATION OF CELL PROLIFERATION | 29 | 814 | 3.53e-18 | 5.664e-16 |
| 30 | POSITIVE REGULATION OF CELL ACTIVATION | 20 | 311 | 1.775e-17 | 2.753e-15 |
| 31 | LEUKOCYTE ACTIVATION | 22 | 414 | 2.069e-17 | 3.105e-15 |
| 32 | POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS | 31 | 1036 | 2.595e-17 | 3.659e-15 |
| 33 | POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS | 31 | 1036 | 2.595e-17 | 3.659e-15 |
| 34 | POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS | 36 | 1492 | 3.081e-17 | 4.217e-15 |
| 35 | POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS | 32 | 1135 | 3.823e-17 | 5.082e-15 |
| 36 | REGULATION OF CELL ACTIVATION | 23 | 484 | 4.047e-17 | 5.23e-15 |
| 37 | POSITIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION | 16 | 162 | 4.302e-17 | 5.41e-15 |
| 38 | REGULATION OF DEFENSE RESPONSE | 27 | 759 | 6.818e-17 | 8.349e-15 |
| 39 | POSITIVE REGULATION OF CELL CELL ADHESION | 18 | 243 | 7.012e-17 | 8.366e-15 |
| 40 | REGULATION OF CELL ADHESION | 25 | 629 | 9.233e-17 | 1.074e-14 |
| 41 | LYMPHOCYTE DIFFERENTIATION | 17 | 209 | 1.137e-16 | 1.291e-14 |
| 42 | REGULATION OF KINASE ACTIVITY | 27 | 776 | 1.184e-16 | 1.311e-14 |
| 43 | CELLULAR RESPONSE TO GROWTH HORMONE STIMULUS | 9 | 20 | 1.216e-16 | 1.316e-14 |
| 44 | REGULATION OF CELL DEATH | 35 | 1472 | 1.58e-16 | 1.671e-14 |
| 45 | REGULATION OF HEMOPOIESIS | 19 | 314 | 3.81e-16 | 3.939e-14 |
| 46 | POSITIVE REGULATION OF CELL COMMUNICATION | 35 | 1532 | 5.403e-16 | 5.465e-14 |
| 47 | REGULATION OF LEUKOCYTE DIFFERENTIATION | 17 | 232 | 6.6e-16 | 6.534e-14 |
| 48 | IMMUNE RESPONSE | 30 | 1100 | 1.194e-15 | 1.157e-13 |
| 49 | POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS | 27 | 867 | 1.828e-15 | 1.735e-13 |
| 50 | NEGATIVE REGULATION OF CELL DEATH | 27 | 872 | 2.104e-15 | 1.958e-13 |
| 51 | REGULATION OF T CELL DIFFERENTIATION | 13 | 107 | 2.92e-15 | 2.615e-13 |
| 52 | PHOSPHORYLATION | 31 | 1228 | 2.922e-15 | 2.615e-13 |
| 53 | NEGATIVE REGULATION OF RESPONSE TO STIMULUS | 32 | 1360 | 6.544e-15 | 5.745e-13 |
| 54 | REGULATION OF T CELL PROLIFERATION | 14 | 147 | 7.536e-15 | 6.481e-13 |
| 55 | POSITIVE REGULATION OF CYTOKINE PRODUCTION | 19 | 370 | 7.661e-15 | 6.481e-13 |
| 56 | ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY | 24 | 689 | 7.956e-15 | 6.494e-13 |
| 57 | REGULATION OF RESPONSE TO STRESS | 33 | 1468 | 7.944e-15 | 6.494e-13 |
| 58 | RESPONSE TO GROWTH HORMONE | 9 | 30 | 9.969e-15 | 7.998e-13 |
| 59 | POSITIVE REGULATION OF CELL ADHESION | 19 | 376 | 1.025e-14 | 8.087e-13 |
| 60 | POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS | 32 | 1395 | 1.331e-14 | 1.032e-12 |
| 61 | PROTEIN PHOSPHORYLATION | 27 | 944 | 1.451e-14 | 1.107e-12 |
| 62 | REGULATION OF TRANSFERASE ACTIVITY | 27 | 946 | 1.527e-14 | 1.146e-12 |
| 63 | CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND | 25 | 799 | 2.264e-14 | 1.672e-12 |
| 64 | LEUKOCYTE DIFFERENTIATION | 17 | 292 | 2.996e-14 | 2.178e-12 |
| 65 | POSITIVE REGULATION OF HEMOPOIESIS | 14 | 163 | 3.215e-14 | 2.302e-12 |
| 66 | RESPONSE TO HORMONE | 26 | 893 | 3.303e-14 | 2.328e-12 |
| 67 | REGULATION OF LEUKOCYTE PROLIFERATION | 15 | 206 | 4.24e-14 | 2.925e-12 |
| 68 | POSITIVE REGULATION OF LEUKOCYTE DIFFERENTIATION | 13 | 131 | 4.275e-14 | 2.925e-12 |
| 69 | REGULATION OF LYMPHOCYTE DIFFERENTIATION | 13 | 132 | 4.724e-14 | 3.186e-12 |
| 70 | POSITIVE REGULATION OF LYMPHOCYTE DIFFERENTIATION | 11 | 80 | 1.087e-13 | 7.222e-12 |
| 71 | RESPONSE TO NITROGEN COMPOUND | 25 | 859 | 1.156e-13 | 7.573e-12 |
| 72 | REGULATION OF CYTOKINE PRODUCTION | 21 | 563 | 1.336e-13 | 8.635e-12 |
| 73 | TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY | 20 | 498 | 1.414e-13 | 9.012e-12 |
| 74 | PEPTIDYL TYROSINE MODIFICATION | 14 | 186 | 2.013e-13 | 1.266e-11 |
| 75 | JAK STAT CASCADE INVOLVED IN GROWTH HORMONE SIGNALING PATHWAY | 7 | 15 | 2.518e-13 | 1.562e-11 |
| 76 | RESPONSE TO ENDOGENOUS STIMULUS | 31 | 1450 | 2.6e-13 | 1.592e-11 |
| 77 | RESPONSE TO PEPTIDE | 18 | 404 | 4.763e-13 | 2.841e-11 |
| 78 | RESPONSE TO OXYGEN CONTAINING COMPOUND | 30 | 1381 | 4.74e-13 | 2.841e-11 |
| 79 | REGULATION OF CELL DIFFERENTIATION | 31 | 1492 | 5.542e-13 | 3.264e-11 |
| 80 | POSITIVE REGULATION OF T CELL PROLIFERATION | 11 | 95 | 7.647e-13 | 4.447e-11 |
| 81 | CELLULAR RESPONSE TO HORMONE STIMULUS | 20 | 552 | 9.478e-13 | 5.444e-11 |
| 82 | LEUKOCYTE CELL CELL ADHESION | 15 | 255 | 9.602e-13 | 5.449e-11 |
| 83 | DEFENSE RESPONSE | 28 | 1231 | 1.183e-12 | 6.632e-11 |
| 84 | POSITIVE REGULATION OF LEUKOCYTE PROLIFERATION | 12 | 136 | 1.774e-12 | 9.827e-11 |
| 85 | NEGATIVE REGULATION OF CELL COMMUNICATION | 27 | 1192 | 3.677e-12 | 2.013e-10 |
| 86 | CELL PROLIFERATION | 21 | 672 | 3.957e-12 | 2.121e-10 |
| 87 | CELLULAR RESPONSE TO ENDOGENOUS STIMULUS | 25 | 1008 | 3.966e-12 | 2.121e-10 |
| 88 | REGULATION OF INFLAMMATORY RESPONSE | 15 | 294 | 7.425e-12 | 3.926e-10 |
| 89 | POSITIVE REGULATION OF DEVELOPMENTAL PROCESS | 26 | 1142 | 9.125e-12 | 4.77e-10 |
| 90 | REGULATION OF ADAPTIVE IMMUNE RESPONSE | 11 | 123 | 1.356e-11 | 7.011e-10 |
| 91 | LEUKOCYTE MIGRATION | 14 | 259 | 1.82e-11 | 9.304e-10 |
| 92 | IMMUNE SYSTEM DEVELOPMENT | 19 | 582 | 2.304e-11 | 1.165e-09 |
| 93 | REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT | 30 | 1672 | 5.897e-11 | 2.951e-09 |
| 94 | REGULATION OF INNATE IMMUNE RESPONSE | 15 | 357 | 1.151e-10 | 5.698e-09 |
| 95 | POSITIVE REGULATION OF IMMUNE RESPONSE | 18 | 563 | 1.165e-10 | 5.705e-09 |
| 96 | REGULATION OF IMMUNE EFFECTOR PROCESS | 16 | 424 | 1.273e-10 | 6.168e-09 |
| 97 | PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS | 32 | 1977 | 1.558e-10 | 7.471e-09 |
| 98 | REGULATION OF LEUKOCYTE MEDIATED IMMUNITY | 11 | 156 | 1.804e-10 | 8.565e-09 |
| 99 | CELLULAR RESPONSE TO NITROGEN COMPOUND | 17 | 505 | 1.85e-10 | 8.694e-09 |
| 100 | NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION | 16 | 437 | 1.982e-10 | 9.224e-09 |
| 101 | T CELL DIFFERENTIATION | 10 | 123 | 3.125e-10 | 1.44e-08 |
| 102 | SINGLE ORGANISM CELL ADHESION | 16 | 459 | 4.061e-10 | 1.853e-08 |
| 103 | RESPONSE TO EXTERNAL STIMULUS | 30 | 1821 | 4.728e-10 | 2.136e-08 |
| 104 | CELLULAR RESPONSE TO PEPTIDE | 13 | 274 | 5.053e-10 | 2.257e-08 |
| 105 | TYROSINE PHOSPHORYLATION OF STAT PROTEIN | 5 | 10 | 5.094e-10 | 2.257e-08 |
| 106 | REGULATION OF CELL KILLING | 8 | 63 | 5.508e-10 | 2.418e-08 |
| 107 | HOMEOSTASIS OF NUMBER OF CELLS | 11 | 175 | 6.181e-10 | 2.688e-08 |
| 108 | REGULATION OF RESPONSE TO INTERFERON GAMMA | 6 | 22 | 6.438e-10 | 2.774e-08 |
| 109 | RESPONSE TO BIOTIC STIMULUS | 21 | 886 | 6.567e-10 | 2.804e-08 |
| 110 | REGULATION OF RESPONSE TO WOUNDING | 15 | 413 | 8.645e-10 | 3.657e-08 |
| 111 | NEGATIVE REGULATION OF PHOSPHORYLATION | 15 | 422 | 1.161e-09 | 4.868e-08 |
| 112 | POSITIVE REGULATION OF CELL DIFFERENTIATION | 20 | 823 | 1.173e-09 | 4.873e-08 |
| 113 | RESPONSE TO ORGANIC CYCLIC COMPOUND | 21 | 917 | 1.219e-09 | 5.018e-08 |
| 114 | REGULATION OF MAPK CASCADE | 18 | 660 | 1.483e-09 | 5.984e-08 |
| 115 | CELL MOTILITY | 20 | 835 | 1.505e-09 | 5.984e-08 |
| 116 | LOCALIZATION OF CELL | 20 | 835 | 1.505e-09 | 5.984e-08 |
| 117 | REGULATION OF RESPONSE TO CYTOKINE STIMULUS | 10 | 144 | 1.475e-09 | 5.984e-08 |
| 118 | POSITIVE REGULATION OF MOLECULAR FUNCTION | 29 | 1791 | 1.523e-09 | 6.005e-08 |
| 119 | PEPTIDYL AMINO ACID MODIFICATION | 20 | 841 | 1.702e-09 | 6.653e-08 |
| 120 | PHOSPHATIDYLINOSITOL 3 PHOSPHATE BIOSYNTHETIC PROCESS | 7 | 49 | 2.953e-09 | 1.145e-07 |
| 121 | CELL CELL ADHESION | 17 | 608 | 3.102e-09 | 1.193e-07 |
| 122 | REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY | 9 | 114 | 3.273e-09 | 1.248e-07 |
| 123 | RESPONSE TO LIPID | 20 | 888 | 4.305e-09 | 1.628e-07 |
| 124 | REGULATION OF GROWTH | 17 | 633 | 5.657e-09 | 2.123e-07 |
| 125 | NATURAL KILLER CELL ACTIVATION | 7 | 55 | 6.818e-09 | 2.538e-07 |
| 126 | NEGATIVE REGULATION OF CELL PROLIFERATION | 17 | 643 | 7.138e-09 | 2.636e-07 |
| 127 | IMMUNE EFFECTOR PROCESS | 15 | 486 | 7.847e-09 | 2.875e-07 |
| 128 | POSITIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION | 8 | 88 | 8.306e-09 | 3.02e-07 |
| 129 | REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS | 7 | 59 | 1.129e-08 | 4.072e-07 |
| 130 | B CELL ACTIVATION | 9 | 132 | 1.195e-08 | 4.279e-07 |
| 131 | RESPONSE TO ALCOHOL | 13 | 362 | 1.451e-08 | 5.154e-07 |
| 132 | POSITIVE REGULATION OF CATALYTIC ACTIVITY | 25 | 1518 | 2.043e-08 | 7.202e-07 |
| 133 | REGULATION OF CD4 POSITIVE ALPHA BETA T CELL ACTIVATION | 6 | 38 | 2.243e-08 | 7.845e-07 |
| 134 | RESPONSE TO VIRUS | 11 | 247 | 2.285e-08 | 7.934e-07 |
| 135 | NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS | 20 | 983 | 2.37e-08 | 8.17e-07 |
| 136 | NEGATIVE REGULATION OF KINASE ACTIVITY | 11 | 250 | 2.587e-08 | 8.849e-07 |
| 137 | RESPONSE TO PROTOZOAN | 5 | 20 | 3.02e-08 | 1.026e-06 |
| 138 | REGULATION OF ALPHA BETA T CELL ACTIVATION | 7 | 68 | 3.1e-08 | 1.045e-06 |
| 139 | NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS | 15 | 541 | 3.257e-08 | 1.082e-06 |
| 140 | NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS | 15 | 541 | 3.257e-08 | 1.082e-06 |
| 141 | HOMEOSTATIC PROCESS | 23 | 1337 | 3.917e-08 | 1.293e-06 |
| 142 | REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY | 14 | 470 | 4.047e-08 | 1.326e-06 |
| 143 | REGULATION OF RESPONSE TO EXTERNAL STIMULUS | 19 | 926 | 4.944e-08 | 1.609e-06 |
| 144 | POSITIVE REGULATION OF KINASE ACTIVITY | 14 | 482 | 5.531e-08 | 1.774e-06 |
| 145 | NEGATIVE REGULATION OF ERBB SIGNALING PATHWAY | 6 | 44 | 5.606e-08 | 1.774e-06 |
| 146 | NEGATIVE REGULATION OF JAK STAT CASCADE | 6 | 44 | 5.606e-08 | 1.774e-06 |
| 147 | NEGATIVE REGULATION OF STAT CASCADE | 6 | 44 | 5.606e-08 | 1.774e-06 |
| 148 | REGULATION OF ALPHA BETA T CELL DIFFERENTIATION | 6 | 46 | 7.382e-08 | 2.321e-06 |
| 149 | RESPONSE TO ESTROGEN | 10 | 218 | 7.84e-08 | 2.448e-06 |
| 150 | REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION | 8 | 118 | 8.427e-08 | 2.614e-06 |
| 151 | PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROCESS | 8 | 120 | 9.606e-08 | 2.96e-06 |
| 152 | NEGATIVE REGULATION OF CELL ADHESION | 10 | 223 | 9.695e-08 | 2.968e-06 |
| 153 | PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING | 5 | 25 | 1.016e-07 | 3.089e-06 |
| 154 | NEGATIVE REGULATION OF IMMUNE RESPONSE | 8 | 121 | 1.025e-07 | 3.096e-06 |
| 155 | REGULATION OF ERBB SIGNALING PATHWAY | 7 | 83 | 1.254e-07 | 3.74e-06 |
| 156 | REGULATION OF T HELPER CELL DIFFERENTIATION | 5 | 26 | 1.253e-07 | 3.74e-06 |
| 157 | POSITIVE REGULATION OF ALPHA BETA T CELL ACTIVATION | 6 | 51 | 1.393e-07 | 4.128e-06 |
| 158 | POSITIVE REGULATION OF CD4 POSITIVE ALPHA BETA T CELL ACTIVATION | 5 | 27 | 1.532e-07 | 4.512e-06 |
| 159 | NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS | 12 | 372 | 1.743e-07 | 5.099e-06 |
| 160 | NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS | 15 | 616 | 1.762e-07 | 5.124e-06 |
| 161 | LOCOMOTION | 20 | 1114 | 1.829e-07 | 5.287e-06 |
| 162 | LEUKOCYTE PROLIFERATION | 7 | 88 | 1.881e-07 | 5.402e-06 |
| 163 | B CELL DIFFERENTIATION | 7 | 89 | 2.034e-07 | 5.77e-06 |
| 164 | INFLAMMATORY RESPONSE | 13 | 454 | 2.03e-07 | 5.77e-06 |
| 165 | EPIDERMAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY | 6 | 55 | 2.209e-07 | 6.228e-06 |
| 166 | REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING | 8 | 138 | 2.831e-07 | 7.888e-06 |
| 167 | NEGATIVE REGULATION OF CELL CELL ADHESION | 8 | 138 | 2.831e-07 | 7.888e-06 |
| 168 | POSITIVE REGULATION OF MAPK CASCADE | 13 | 470 | 3.013e-07 | 8.346e-06 |
| 169 | RESPONSE TO INTERLEUKIN 4 | 5 | 31 | 3.177e-07 | 8.748e-06 |
| 170 | MOVEMENT OF CELL OR SUBCELLULAR COMPONENT | 21 | 1275 | 3.574e-07 | 9.783e-06 |
| 171 | LEUKOCYTE HOMEOSTASIS | 6 | 60 | 3.743e-07 | 1.018e-05 |
| 172 | MYELOID LEUKOCYTE MIGRATION | 7 | 99 | 4.23e-07 | 1.138e-05 |
| 173 | LIPID PHOSPHORYLATION | 7 | 99 | 4.23e-07 | 1.138e-05 |
| 174 | RESPONSE TO ESTRADIOL | 8 | 146 | 4.36e-07 | 1.166e-05 |
| 175 | REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION | 7 | 100 | 4.531e-07 | 1.205e-05 |
| 176 | NEGATIVE REGULATION OF IMMUNE EFFECTOR PROCESS | 7 | 102 | 5.187e-07 | 1.364e-05 |
| 177 | NEGATIVE REGULATION OF HOMOTYPIC CELL CELL ADHESION | 7 | 102 | 5.187e-07 | 1.364e-05 |
| 178 | RESPONSE TO INSULIN | 9 | 205 | 5.251e-07 | 1.373e-05 |
| 179 | RESPONSE TO STEROID HORMONE | 13 | 497 | 5.671e-07 | 1.474e-05 |
| 180 | NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS | 19 | 1087 | 5.885e-07 | 1.521e-05 |
| 181 | REGULATION OF CHEMOKINE PRODUCTION | 6 | 65 | 6.06e-07 | 1.558e-05 |
| 182 | REGULATION OF MULTICELLULAR ORGANISM GROWTH | 6 | 66 | 6.641e-07 | 1.698e-05 |
| 183 | NEGATIVE REGULATION OF CYTOKINE PRODUCTION | 9 | 211 | 6.687e-07 | 1.7e-05 |
| 184 | POSITIVE REGULATION OF IMMUNE EFFECTOR PROCESS | 8 | 156 | 7.22e-07 | 1.826e-05 |
| 185 | NEGATIVE REGULATION OF TRANSFERASE ACTIVITY | 11 | 351 | 7.831e-07 | 1.97e-05 |
| 186 | POSITIVE REGULATION OF ALPHA BETA T CELL DIFFERENTIATION | 5 | 37 | 7.972e-07 | 1.994e-05 |
| 187 | INTERFERON GAMMA MEDIATED SIGNALING PATHWAY | 6 | 70 | 9.439e-07 | 2.349e-05 |
| 188 | ADAPTIVE IMMUNE RESPONSE | 10 | 288 | 1.022e-06 | 2.529e-05 |
| 189 | REGULATION OF TYPE I INTERFERON MEDIATED SIGNALING PATHWAY | 5 | 39 | 1.045e-06 | 2.559e-05 |
| 190 | POSITIVE REGULATION OF INFLAMMATORY RESPONSE | 7 | 113 | 1.04e-06 | 2.559e-05 |
| 191 | POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY | 10 | 289 | 1.054e-06 | 2.569e-05 |
| 192 | POSITIVE REGULATION OF TRANSFERASE ACTIVITY | 14 | 616 | 1.075e-06 | 2.605e-05 |
| 193 | RESPONSE TO BACTERIUM | 13 | 528 | 1.117e-06 | 2.681e-05 |
| 194 | POSITIVE REGULATION OF DEFENSE RESPONSE | 11 | 364 | 1.118e-06 | 2.681e-05 |
| 195 | REGULATION OF ACTIVATED T CELL PROLIFERATION | 5 | 40 | 1.19e-06 | 2.84e-05 |
| 196 | POSITIVE REGULATION OF ADAPTIVE IMMUNE RESPONSE | 6 | 73 | 1.212e-06 | 2.877e-05 |
| 197 | BIOLOGICAL ADHESION | 18 | 1032 | 1.264e-06 | 2.985e-05 |
| 198 | LEUKOCYTE CHEMOTAXIS | 7 | 117 | 1.316e-06 | 3.092e-05 |
| 199 | POSITIVE REGULATION OF T HELPER CELL DIFFERENTIATION | 4 | 18 | 1.331e-06 | 3.113e-05 |
| 200 | GLUCOSE HOMEOSTASIS | 8 | 170 | 1.382e-06 | 3.199e-05 |
| 201 | CARBOHYDRATE HOMEOSTASIS | 8 | 170 | 1.382e-06 | 3.199e-05 |
| 202 | REGULATION OF EPITHELIAL CELL DIFFERENTIATION | 7 | 122 | 1.744e-06 | 3.996e-05 |
| 203 | CELLULAR RESPONSE TO INTERFERON GAMMA | 7 | 122 | 1.744e-06 | 3.996e-05 |
| 204 | ERBB SIGNALING PATHWAY | 6 | 79 | 1.934e-06 | 4.412e-05 |
| 205 | INOSITOL LIPID MEDIATED SIGNALING | 7 | 124 | 1.945e-06 | 4.414e-05 |
| 206 | RESPONSE TO LEPTIN | 4 | 20 | 2.093e-06 | 4.727e-05 |
| 207 | NEGATIVE REGULATION OF MOLECULAR FUNCTION | 18 | 1079 | 2.378e-06 | 5.345e-05 |
| 208 | REGULATION OF MYELOID CELL DIFFERENTIATION | 8 | 183 | 2.399e-06 | 5.368e-05 |
| 209 | REGULATION OF MAP KINASE ACTIVITY | 10 | 319 | 2.561e-06 | 5.68e-05 |
| 210 | REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION OF STAT PROTEIN | 4 | 21 | 2.576e-06 | 5.68e-05 |
| 211 | POSITIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION OF STAT PROTEIN | 4 | 21 | 2.576e-06 | 5.68e-05 |
| 212 | REGULATION OF IMMUNOGLOBULIN PRODUCTION | 5 | 47 | 2.703e-06 | 5.915e-05 |
| 213 | RESPONSE TO MOLECULE OF BACTERIAL ORIGIN | 10 | 321 | 2.708e-06 | 5.915e-05 |
| 214 | POSITIVE REGULATION OF LEUKOCYTE MEDIATED IMMUNITY | 6 | 85 | 2.975e-06 | 6.47e-05 |
| 215 | CELLULAR RESPONSE TO INTERLEUKIN 6 | 4 | 22 | 3.137e-06 | 6.757e-05 |
| 216 | REGULATION OF T HELPER 1 TYPE IMMUNE RESPONSE | 4 | 22 | 3.137e-06 | 6.757e-05 |
| 217 | GROWTH | 11 | 410 | 3.53e-06 | 7.569e-05 |
| 218 | PHOSPHATIDYLINOSITOL METABOLIC PROCESS | 8 | 193 | 3.564e-06 | 7.606e-05 |
| 219 | POSITIVE REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS | 4 | 23 | 3.784e-06 | 8.039e-05 |
| 220 | CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE | 7 | 139 | 4.163e-06 | 8.804e-05 |
| 221 | DEFENSE RESPONSE TO OTHER ORGANISM | 12 | 505 | 4.303e-06 | 9.059e-05 |
| 222 | REGULATION OF BODY FLUID LEVELS | 12 | 506 | 4.39e-06 | 9.202e-05 |
| 223 | PLATELET ACTIVATION | 7 | 142 | 4.795e-06 | 1e-04 |
| 224 | REGULATION OF LEUKOCYTE MEDIATED CYTOTOXICITY | 5 | 53 | 4.946e-06 | 0.0001027 |
| 225 | POSITIVE REGULATION OF CELL DEATH | 13 | 605 | 4.978e-06 | 0.0001029 |
| 226 | RESPONSE TO INTERFERON GAMMA | 7 | 144 | 5.259e-06 | 0.0001083 |
| 227 | NEGATIVE REGULATION OF MAPK CASCADE | 7 | 145 | 5.505e-06 | 0.0001128 |
| 228 | REGULATION OF TYPE 2 IMMUNE RESPONSE | 4 | 26 | 6.319e-06 | 0.0001278 |
| 229 | CELLULAR RESPONSE TO INTERLEUKIN 4 | 4 | 26 | 6.319e-06 | 0.0001278 |
| 230 | RESPONSE TO INTERLEUKIN 6 | 4 | 26 | 6.319e-06 | 0.0001278 |
| 231 | INNATE IMMUNE RESPONSE | 13 | 619 | 6.371e-06 | 0.0001283 |
| 232 | REGULATION OF INTERFERON GAMMA PRODUCTION | 6 | 97 | 6.426e-06 | 0.0001289 |
| 233 | LIPID MODIFICATION | 8 | 210 | 6.64e-06 | 0.0001326 |
| 234 | GLYCEROLIPID BIOSYNTHETIC PROCESS | 8 | 211 | 6.875e-06 | 0.0001367 |
| 235 | EXTRINSIC APOPTOTIC SIGNALING PATHWAY | 6 | 99 | 7.232e-06 | 0.0001432 |
| 236 | REGULATION OF NATURAL KILLER CELL ACTIVATION | 4 | 27 | 7.392e-06 | 0.0001457 |
| 237 | NEGATIVE REGULATION OF INFLAMMATORY RESPONSE | 6 | 100 | 7.664e-06 | 0.0001505 |
| 238 | REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE | 6 | 101 | 8.118e-06 | 0.0001587 |
| 239 | POSITIVE REGULATION OF ACUTE INFLAMMATORY RESPONSE | 4 | 28 | 8.593e-06 | 0.0001666 |
| 240 | POSITIVE REGULATION OF ACTIVATED T CELL PROLIFERATION | 4 | 28 | 8.593e-06 | 0.0001666 |
| 241 | REGULATION OF DEVELOPMENTAL GROWTH | 9 | 289 | 8.816e-06 | 0.0001702 |
| 242 | T CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE | 5 | 60 | 9.172e-06 | 0.0001763 |
| 243 | POSITIVE REGULATION OF SECRETION | 10 | 370 | 9.463e-06 | 0.0001812 |
| 244 | NEGATIVE REGULATION OF CELL ACTIVATION | 7 | 158 | 9.674e-06 | 0.0001845 |
| 245 | CELLULAR RESPONSE TO LIPID | 11 | 457 | 9.862e-06 | 0.0001873 |
| 246 | POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS | 9 | 296 | 1.068e-05 | 0.000202 |
| 247 | CELL CHEMOTAXIS | 7 | 162 | 1.139e-05 | 0.0002137 |
| 248 | POSITIVE REGULATION OF RESPONSE TO WOUNDING | 7 | 162 | 1.139e-05 | 0.0002137 |
| 249 | DEFENSE RESPONSE TO VIRUS | 7 | 164 | 1.234e-05 | 0.0002305 |
| 250 | POSITIVE REGULATION OF IMMUNOGLOBULIN PRODUCTION | 4 | 31 | 1.306e-05 | 0.0002431 |
| 251 | CHEMICAL HOMEOSTASIS | 15 | 874 | 1.324e-05 | 0.0002455 |
| 252 | REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS | 5 | 65 | 1.362e-05 | 0.0002514 |
| 253 | PHOSPHOLIPID BIOSYNTHETIC PROCESS | 8 | 235 | 1.506e-05 | 0.0002769 |
| 254 | POSITIVE REGULATION OF TYROSINE PHOSPHORYLATION OF STAT1 PROTEIN | 3 | 11 | 1.614e-05 | 0.0002918 |
| 255 | OXALOACETATE METABOLIC PROCESS | 3 | 11 | 1.614e-05 | 0.0002918 |
| 256 | CREATINE METABOLIC PROCESS | 3 | 11 | 1.614e-05 | 0.0002918 |
| 257 | REGULATION OF T HELPER 2 CELL DIFFERENTIATION | 3 | 11 | 1.614e-05 | 0.0002918 |
| 258 | NEGATIVE REGULATION OF NEURON DEATH | 7 | 171 | 1.618e-05 | 0.0002918 |
| 259 | RESPONSE TO TYPE I INTERFERON | 5 | 68 | 1.699e-05 | 0.0003041 |
| 260 | ORGAN GROWTH | 5 | 68 | 1.699e-05 | 0.0003041 |
| 261 | POSITIVE REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY | 5 | 69 | 1.826e-05 | 0.0003254 |
| 262 | MAMMARY GLAND DEVELOPMENT | 6 | 117 | 1.886e-05 | 0.000335 |
| 263 | SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION | 10 | 404 | 2.021e-05 | 0.0003576 |
| 264 | NATURAL KILLER CELL DIFFERENTIATION | 3 | 12 | 2.145e-05 | 0.0003752 |
| 265 | NEGATIVE REGULATION OF CD4 POSITIVE ALPHA BETA T CELL DIFFERENTIATION | 3 | 12 | 2.145e-05 | 0.0003752 |
| 266 | POSITIVE REGULATION OF GLUCOSE IMPORT IN RESPONSE TO INSULIN STIMULUS | 3 | 12 | 2.145e-05 | 0.0003752 |
| 267 | REPRODUCTIVE SYSTEM DEVELOPMENT | 10 | 408 | 2.199e-05 | 0.0003832 |
| 268 | REGULATION OF B CELL ACTIVATION | 6 | 121 | 2.283e-05 | 0.0003964 |
| 269 | POSITIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY | 4 | 36 | 2.402e-05 | 0.0004155 |
| 270 | REGULATION OF ACUTE INFLAMMATORY RESPONSE | 5 | 74 | 2.569e-05 | 0.000441 |
| 271 | NEGATIVE REGULATION OF HORMONE SECRETION | 5 | 74 | 2.569e-05 | 0.000441 |
| 272 | NEGATIVE REGULATION OF ADAPTIVE IMMUNE RESPONSE | 4 | 37 | 2.683e-05 | 0.000459 |
| 273 | POSITIVE REGULATION OF PROTEIN IMPORT INTO NUCLEUS TRANSLOCATION | 3 | 13 | 2.779e-05 | 0.0004719 |
| 274 | ENERGY HOMEOSTASIS | 3 | 13 | 2.779e-05 | 0.0004719 |
| 275 | RESPONSE TO UV | 6 | 126 | 2.871e-05 | 0.0004859 |
| 276 | B CELL PROLIFERATION | 4 | 38 | 2.988e-05 | 0.0005038 |
| 277 | NEGATIVE REGULATION OF HEMOPOIESIS | 6 | 128 | 3.138e-05 | 0.0005272 |
| 278 | NEGATIVE REGULATION OF CATALYTIC ACTIVITY | 14 | 829 | 3.168e-05 | 0.0005302 |
| 279 | POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS | 6 | 129 | 3.279e-05 | 0.0005449 |
| 280 | NUCLEAR IMPORT | 6 | 129 | 3.279e-05 | 0.0005449 |
| 281 | POSITIVE REGULATION OF CELL KILLING | 4 | 39 | 3.318e-05 | 0.0005494 |
| 282 | REGULATION OF CELL CYCLE | 15 | 949 | 3.454e-05 | 0.0005699 |
| 283 | INSULIN RECEPTOR SIGNALING PATHWAY | 5 | 80 | 3.749e-05 | 0.0006164 |
| 284 | REGULATION OF HYDROLASE ACTIVITY | 18 | 1327 | 3.98e-05 | 0.00065 |
| 285 | POSITIVE REGULATION OF PROTEIN KINASE B SIGNALING | 5 | 81 | 3.981e-05 | 0.00065 |
| 286 | LACTATION | 4 | 41 | 4.056e-05 | 0.0006599 |
| 287 | NEGATIVE REGULATION OF LEUKOCYTE DIFFERENTIATION | 5 | 82 | 4.224e-05 | 0.0006848 |
| 288 | POSITIVE REGULATION OF GENE EXPRESSION | 21 | 1733 | 4.315e-05 | 0.0006971 |
| 289 | NEGATIVE REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION | 3 | 15 | 4.391e-05 | 0.0006997 |
| 290 | T CELL LINEAGE COMMITMENT | 3 | 15 | 4.391e-05 | 0.0006997 |
| 291 | NEGATIVE REGULATION OF ALPHA BETA T CELL DIFFERENTIATION | 3 | 15 | 4.391e-05 | 0.0006997 |
| 292 | NEGATIVE REGULATION OF CD4 POSITIVE ALPHA BETA T CELL ACTIVATION | 3 | 15 | 4.391e-05 | 0.0006997 |
| 293 | REGULATION OF MUSCLE CELL APOPTOTIC PROCESS | 4 | 43 | 4.907e-05 | 0.0007714 |
| 294 | MYELOID LEUKOCYTE MEDIATED IMMUNITY | 4 | 43 | 4.907e-05 | 0.0007714 |
| 295 | REGULATION OF INSULIN RECEPTOR SIGNALING PATHWAY | 4 | 43 | 4.907e-05 | 0.0007714 |
| 296 | ACUTE PHASE RESPONSE | 4 | 43 | 4.907e-05 | 0.0007714 |
| 297 | POSITIVE REGULATION OF B CELL ACTIVATION | 5 | 86 | 5.312e-05 | 0.0008323 |
| 298 | NEGATIVE REGULATION OF CHEMOKINE PRODUCTION | 3 | 16 | 5.386e-05 | 0.0008354 |
| 299 | CELLULAR RESPONSE TO LEPTIN STIMULUS | 3 | 16 | 5.386e-05 | 0.0008354 |
| 300 | REGULATION OF TYROSINE PHOSPHORYLATION OF STAT1 PROTEIN | 3 | 16 | 5.386e-05 | 0.0008354 |
| 301 | NEGATIVE REGULATION OF DEFENSE RESPONSE | 6 | 144 | 6.072e-05 | 0.0009386 |
| 302 | POSITIVE REGULATION OF PROTEIN SECRETION | 7 | 211 | 6.2e-05 | 0.0009552 |
| 303 | CELL DEATH | 15 | 1001 | 6.342e-05 | 0.0009739 |
| 304 | REGULATION OF GLUCOSE IMPORT IN RESPONSE TO INSULIN STIMULUS | 3 | 17 | 6.518e-05 | 0.0009977 |
| 305 | CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND | 10 | 465 | 6.623e-05 | 0.00101 |
| 306 | RESPONSE TO ANTIBIOTIC | 4 | 47 | 6.991e-05 | 0.001063 |
| 307 | REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS | 7 | 218 | 7.611e-05 | 0.001154 |
| 308 | POSITIVE REGULATION OF NATURAL KILLER CELL ACTIVATION | 3 | 18 | 7.795e-05 | 0.001178 |
| 309 | RESPONSE TO GROWTH FACTOR | 10 | 475 | 7.9e-05 | 0.00119 |
| 310 | GLYCEROPHOSPHOLIPID METABOLIC PROCESS | 8 | 297 | 7.931e-05 | 0.00119 |
| 311 | REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT | 7 | 220 | 8.06e-05 | 0.001206 |
| 312 | REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS | 6 | 152 | 8.196e-05 | 0.001222 |
| 313 | POSITIVE REGULATION OF CHEMOKINE PRODUCTION | 4 | 49 | 8.245e-05 | 0.001226 |
| 314 | LYMPHOCYTE HOMEOSTASIS | 4 | 50 | 8.93e-05 | 0.001323 |
| 315 | REGULATION OF PROTEIN SECRETION | 9 | 389 | 9.001e-05 | 0.00133 |
| 316 | PROTEIN IMPORT | 6 | 155 | 9.13e-05 | 0.001344 |
| 317 | NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS | 13 | 801 | 9.316e-05 | 0.001367 |
| 318 | NEGATIVE REGULATION OF CELLULAR CATABOLIC PROCESS | 6 | 156 | 9.459e-05 | 0.001375 |
| 319 | PROTEIN LOCALIZATION TO NUCLEUS | 6 | 156 | 9.459e-05 | 0.001375 |
| 320 | NEGATIVE REGULATION OF RESPONSE TO WOUNDING | 6 | 156 | 9.459e-05 | 0.001375 |
| 321 | LYMPHOCYTE ACTIVATION INVOLVED IN IMMUNE RESPONSE | 5 | 98 | 9.91e-05 | 0.001436 |
| 322 | GLAND DEVELOPMENT | 9 | 395 | 0.0001011 | 0.001461 |
| 323 | HORMONE MEDIATED SIGNALING PATHWAY | 6 | 158 | 0.0001015 | 0.001462 |
| 324 | NEGATIVE REGULATION OF ERK1 AND ERK2 CASCADE | 4 | 52 | 0.0001042 | 0.001488 |
| 325 | NEGATIVE REGULATION OF T CELL PROLIFERATION | 4 | 52 | 0.0001042 | 0.001488 |
| 326 | REGULATION OF T CELL MEDIATED IMMUNITY | 4 | 52 | 0.0001042 | 0.001488 |
| 327 | MEGAKARYOCYTE DIFFERENTIATION | 3 | 20 | 0.0001082 | 0.001534 |
| 328 | X2 OXOGLUTARATE METABOLIC PROCESS | 3 | 20 | 0.0001082 | 0.001534 |
| 329 | HEMOSTASIS | 8 | 311 | 0.0001091 | 0.001544 |
| 330 | MAMMARY GLAND EPITHELIUM DEVELOPMENT | 4 | 53 | 0.0001123 | 0.001579 |
| 331 | REGULATION OF NITRIC OXIDE BIOSYNTHETIC PROCESS | 4 | 53 | 0.0001123 | 0.001579 |
| 332 | REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION | 5 | 101 | 0.0001143 | 0.001602 |
| 333 | POSITIVE REGULATION OF TRANSPORT | 14 | 936 | 0.0001166 | 0.001629 |
| 334 | ALPHA BETA T CELL ACTIVATION | 4 | 54 | 0.0001209 | 0.001679 |
| 335 | DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION | 11 | 602 | 0.0001206 | 0.001679 |
| 336 | REGULATION OF PROTEIN IMPORT INTO NUCLEUS TRANSLOCATION | 3 | 21 | 0.0001258 | 0.001742 |
| 337 | DEFENSE RESPONSE TO BACTERIUM | 7 | 237 | 0.0001281 | 0.001769 |
| 338 | REGULATION OF ERK1 AND ERK2 CASCADE | 7 | 238 | 0.0001315 | 0.0018 |
| 339 | POSITIVE REGULATION OF PROTEIN IMPORT | 5 | 104 | 0.0001313 | 0.0018 |
| 340 | REGULATION OF INTERLEUKIN 6 PRODUCTION | 5 | 104 | 0.0001313 | 0.0018 |
| 341 | NEGATIVE REGULATION OF CELL DIFFERENTIATION | 11 | 609 | 0.0001334 | 0.001821 |
| 342 | REGULATION OF SYSTEM PROCESS | 10 | 507 | 0.0001349 | 0.001835 |
| 343 | MORPHOGENESIS OF A BRANCHING STRUCTURE | 6 | 167 | 0.0001375 | 0.001865 |
| 344 | IMMUNE RESPONSE REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY | 8 | 323 | 0.0001416 | 0.001915 |
| 345 | REGULATION OF INTERLEUKIN 17 PRODUCTION | 3 | 22 | 0.0001451 | 0.001957 |
| 346 | REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION | 5 | 108 | 0.0001568 | 0.002108 |
| 347 | REGULATION OF DNA RECOMBINATION | 4 | 58 | 0.0001599 | 0.002144 |
| 348 | POSITIVE REGULATION OF LOCOMOTION | 9 | 420 | 0.0001605 | 0.002146 |
| 349 | REGULATION OF T CELL MEDIATED CYTOTOXICITY | 3 | 23 | 0.0001663 | 0.002192 |
| 350 | LEUKOCYTE APOPTOTIC PROCESS | 3 | 23 | 0.0001663 | 0.002192 |
| 351 | REGULATION OF METANEPHROS DEVELOPMENT | 3 | 23 | 0.0001663 | 0.002192 |
| 352 | BRANCHED CHAIN AMINO ACID METABOLIC PROCESS | 3 | 23 | 0.0001663 | 0.002192 |
| 353 | NEGATIVE REGULATION OF ALPHA BETA T CELL ACTIVATION | 3 | 23 | 0.0001663 | 0.002192 |
| 354 | POSITIVE REGULATION OF CELL CYCLE | 8 | 332 | 0.0001709 | 0.002246 |
| 355 | REGULATION OF GLUCOSE IMPORT | 4 | 60 | 0.0001824 | 0.002384 |
| 356 | POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION | 4 | 60 | 0.0001824 | 0.002384 |
| 357 | REGULATION OF NEURON DEATH | 7 | 252 | 0.000187 | 0.002437 |
| 358 | REGULATION OF ISOTYPE SWITCHING | 3 | 24 | 0.0001894 | 0.002462 |
| 359 | REGULATION OF TISSUE REMODELING | 4 | 62 | 0.0002072 | 0.002686 |
| 360 | CELLULAR RESPONSE TO ALCOHOL | 5 | 115 | 0.0002103 | 0.002719 |
| 361 | CELLULAR EXTRAVASATION | 3 | 25 | 0.0002145 | 0.002765 |
| 362 | RESPONSE TO KETONE | 6 | 182 | 0.0002194 | 0.00282 |
| 363 | TISSUE DEVELOPMENT | 18 | 1518 | 0.0002204 | 0.002826 |
| 364 | REGULATION OF PROTEIN IMPORT | 6 | 183 | 0.000226 | 0.002889 |
| 365 | POSITIVE REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE | 4 | 64 | 0.0002343 | 0.002987 |
| 366 | REGULATION OF HORMONE SECRETION | 7 | 262 | 0.0002371 | 0.003015 |
| 367 | POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER | 14 | 1004 | 0.0002413 | 0.003056 |
| 368 | CELLULAR RESPONSE TO VITAMIN | 3 | 26 | 0.0002417 | 0.003056 |
| 369 | CYTOKINE PRODUCTION | 5 | 120 | 0.0002564 | 0.003233 |
| 370 | REGULATION OF CELLULAR COMPONENT MOVEMENT | 12 | 771 | 0.0002601 | 0.003271 |
| 371 | CELLULAR RESPONSE TO UV | 4 | 66 | 0.0002639 | 0.00331 |
| 372 | POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT | 5 | 121 | 0.0002665 | 0.003324 |
| 373 | REGULATION OF PROTEIN KINASE B SIGNALING | 5 | 121 | 0.0002665 | 0.003324 |
| 374 | REGULATION OF CELLULAR PROTEIN LOCALIZATION | 10 | 552 | 0.0002676 | 0.003329 |
| 375 | GLYCEROLIPID METABOLIC PROCESS | 8 | 356 | 0.0002741 | 0.003401 |
| 376 | NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS | 7 | 274 | 0.0003111 | 0.00385 |
| 377 | NEGATIVE REGULATION OF LEUKOCYTE PROLIFERATION | 4 | 69 | 0.0003132 | 0.003864 |
| 378 | LIPID METABOLIC PROCESS | 15 | 1158 | 0.0003139 | 0.003864 |
| 379 | REGULATION OF GTPASE ACTIVITY | 11 | 673 | 0.0003159 | 0.003878 |
| 380 | PHOSPHOLIPID METABOLIC PROCESS | 8 | 364 | 0.0003181 | 0.003895 |
| 381 | TAXIS | 9 | 464 | 0.0003351 | 0.004074 |
| 382 | T CELL DIFFERENTIATION INVOLVED IN IMMUNE RESPONSE | 3 | 29 | 0.0003362 | 0.004074 |
| 383 | CELLULAR LIPID METABOLIC PROCESS | 13 | 913 | 0.0003362 | 0.004074 |
| 384 | REPRODUCTION | 16 | 1297 | 0.000335 | 0.004074 |
| 385 | ACTIVATION OF PROTEIN KINASE ACTIVITY | 7 | 279 | 0.000347 | 0.004193 |
| 386 | BODY FLUID SECRETION | 4 | 71 | 0.0003494 | 0.004212 |
| 387 | NEGATIVE REGULATION OF SECRETION | 6 | 200 | 0.0003639 | 0.004375 |
| 388 | ENERGY RESERVE METABOLIC PROCESS | 4 | 72 | 0.0003687 | 0.00441 |
| 389 | WOUND HEALING | 9 | 470 | 0.0003679 | 0.00441 |
| 390 | REGULATION OF LIPID METABOLIC PROCESS | 7 | 282 | 0.00037 | 0.004415 |
| 391 | NEGATIVE REGULATION OF MAP KINASE ACTIVITY | 4 | 73 | 0.0003887 | 0.004613 |
| 392 | ACUTE INFLAMMATORY RESPONSE | 4 | 73 | 0.0003887 | 0.004613 |
| 393 | REGULATION OF EPITHELIAL CELL PROLIFERATION | 7 | 285 | 0.0003943 | 0.004656 |
| 394 | NEGATIVE REGULATION OF CATABOLIC PROCESS | 6 | 203 | 0.0003939 | 0.004656 |
| 395 | NEGATIVE REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS | 3 | 31 | 0.0004108 | 0.004827 |
| 396 | HOMEOSTASIS OF NUMBER OF CELLS WITHIN A TISSUE | 3 | 31 | 0.0004108 | 0.004827 |
| 397 | APOPTOTIC SIGNALING PATHWAY | 7 | 289 | 0.0004286 | 0.005023 |
| 398 | GRANULOCYTE MIGRATION | 4 | 75 | 0.0004309 | 0.005038 |
| 399 | REGULATION OF SECRETION | 11 | 699 | 0.000435 | 0.005073 |
| 400 | NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS | 5 | 135 | 0.0004414 | 0.005134 |
| 401 | NEGATIVE REGULATION OF T CELL DIFFERENTIATION | 3 | 32 | 0.0004518 | 0.005242 |
| 402 | RESPONSE TO ETHANOL | 5 | 136 | 0.0004565 | 0.005284 |
| 403 | EPITHELIUM DEVELOPMENT | 13 | 945 | 0.0004666 | 0.005387 |
| 404 | CELLULAR RESPONSE TO RADIATION | 5 | 137 | 0.0004721 | 0.005437 |
| 405 | PLACENTA DEVELOPMENT | 5 | 138 | 0.000488 | 0.005607 |
| 406 | LYMPHOCYTE COSTIMULATION | 4 | 78 | 0.0005003 | 0.005734 |
| 407 | MULTI MULTICELLULAR ORGANISM PROCESS | 6 | 213 | 0.0005081 | 0.005809 |
| 408 | REGULATION OF PROTEIN DEACETYLATION | 3 | 34 | 0.0005413 | 0.006159 |
| 409 | T CELL HOMEOSTASIS | 3 | 34 | 0.0005413 | 0.006159 |
| 410 | REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER | 19 | 1784 | 0.0005584 | 0.006337 |
| 411 | POSITIVE REGULATION OF MYELOID CELL DIFFERENTIATION | 4 | 81 | 0.0005773 | 0.006536 |
| 412 | NEGATIVE REGULATION OF INTERFERON GAMMA PRODUCTION | 3 | 35 | 0.0005901 | 0.006648 |
| 413 | REGULATION OF NATURAL KILLER CELL MEDIATED IMMUNITY | 3 | 35 | 0.0005901 | 0.006648 |
| 414 | CELLULAR RESPONSE TO INSULIN STIMULUS | 5 | 146 | 0.0006307 | 0.007064 |
| 415 | REGULATION OF CATABOLIC PROCESS | 11 | 731 | 0.0006315 | 0.007064 |
| 416 | T CELL RECEPTOR SIGNALING PATHWAY | 5 | 146 | 0.0006307 | 0.007064 |
| 417 | ORGAN REGENERATION | 4 | 83 | 0.0006331 | 0.007065 |
| 418 | NEGATIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION | 3 | 36 | 0.0006415 | 0.00709 |
| 419 | T CELL PROLIFERATION | 3 | 36 | 0.0006415 | 0.00709 |
| 420 | NEGATIVE REGULATION OF BLOOD CIRCULATION | 3 | 36 | 0.0006415 | 0.00709 |
| 421 | T CELL SELECTION | 3 | 36 | 0.0006415 | 0.00709 |
| 422 | FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY | 4 | 84 | 0.0006624 | 0.007304 |
| 423 | TRICARBOXYLIC ACID METABOLIC PROCESS | 3 | 37 | 0.0006958 | 0.0076 |
| 424 | REGULATION OF CYTOKINE SECRETION | 5 | 149 | 0.0006915 | 0.0076 |
| 425 | REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION | 3 | 37 | 0.0006958 | 0.0076 |
| 426 | NEGATIVE REGULATION OF EPITHELIAL CELL DIFFERENTIATION | 3 | 37 | 0.0006958 | 0.0076 |
| 427 | POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION | 9 | 514 | 0.0007002 | 0.00763 |
| 428 | POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS | 4 | 86 | 0.0007238 | 0.007869 |
| 429 | RESPONSE TO RADIATION | 8 | 413 | 0.0007315 | 0.007934 |
| 430 | REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS | 3 | 38 | 0.0007529 | 0.008128 |
| 431 | REGULATION OF GLUCONEOGENESIS | 3 | 38 | 0.0007529 | 0.008128 |
| 432 | ERBB2 SIGNALING PATHWAY | 3 | 39 | 0.0008128 | 0.008675 |
| 433 | ASTROCYTE DIFFERENTIATION | 3 | 39 | 0.0008128 | 0.008675 |
| 434 | CELLULAR RESPONSE TO NUTRIENT | 3 | 39 | 0.0008128 | 0.008675 |
| 435 | PEPTIDYL TYROSINE AUTOPHOSPHORYLATION | 3 | 39 | 0.0008128 | 0.008675 |
| 436 | EMBRYO IMPLANTATION | 3 | 39 | 0.0008128 | 0.008675 |
| 437 | EPITHELIAL CELL PROLIFERATION | 4 | 89 | 0.0008234 | 0.008767 |
| 438 | POSITIVE REGULATION OF DEVELOPMENTAL GROWTH | 5 | 156 | 0.0008504 | 0.009034 |
| 439 | REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY | 3 | 40 | 0.0008758 | 0.009261 |
| 440 | NEGATIVE REGULATION OF LYMPHOCYTE DIFFERENTIATION | 3 | 40 | 0.0008758 | 0.009261 |
| 441 | CELLULAR RESPONSE TO LIGHT STIMULUS | 4 | 91 | 0.0008949 | 0.009442 |
| 442 | REGULATION OF B CELL MEDIATED IMMUNITY | 3 | 41 | 0.0009417 | 0.009913 |
| Num | GO | Overlap | Size | P Value | Adj. P Value |
|---|---|---|---|---|---|
| 1 | CYTOKINE RECEPTOR ACTIVITY | 30 | 89 | 3.047e-49 | 2.83e-46 |
| 2 | CYTOKINE RECEPTOR BINDING | 24 | 271 | 3.302e-24 | 1.534e-21 |
| 3 | CYTOKINE BINDING | 16 | 92 | 3.512e-21 | 1.088e-18 |
| 4 | RECEPTOR BINDING | 38 | 1476 | 3.084e-19 | 7.162e-17 |
| 5 | SIGNAL TRANSDUCER ACTIVITY | 40 | 1731 | 1.12e-18 | 2.081e-16 |
| 6 | CYTOKINE ACTIVITY | 15 | 219 | 1.044e-13 | 1.617e-11 |
| 7 | KINASE REGULATOR ACTIVITY | 14 | 186 | 2.013e-13 | 2.672e-11 |
| 8 | SIGNALING RECEPTOR ACTIVITY | 30 | 1393 | 5.922e-13 | 6.878e-11 |
| 9 | RECEPTOR ACTIVITY | 30 | 1649 | 4.188e-11 | 4.323e-09 |
| 10 | KINASE INHIBITOR ACTIVITY | 9 | 89 | 3.532e-10 | 3.221e-08 |
| 11 | KINASE BINDING | 18 | 606 | 3.813e-10 | 3.221e-08 |
| 12 | GROWTH FACTOR RECEPTOR BINDING | 10 | 129 | 5.006e-10 | 3.875e-08 |
| 13 | INSULIN RECEPTOR SUBSTRATE BINDING | 5 | 11 | 9.305e-10 | 6.649e-08 |
| 14 | X1 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY | 7 | 43 | 1.133e-09 | 7.52e-08 |
| 15 | PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY | 8 | 70 | 1.307e-09 | 8.095e-08 |
| 16 | MOLECULAR FUNCTION REGULATOR | 25 | 1353 | 2.012e-09 | 1.168e-07 |
| 17 | PHOSPHATIDYLINOSITOL KINASE ACTIVITY | 7 | 51 | 3.95e-09 | 2.158e-07 |
| 18 | KINASE ACTIVITY | 19 | 842 | 1.086e-08 | 5.606e-07 |
| 19 | ENZYME BINDING | 26 | 1737 | 6.851e-08 | 3.35e-06 |
| 20 | HORMONE RECEPTOR BINDING | 9 | 168 | 9.696e-08 | 4.504e-06 |
| 21 | GROWTH FACTOR BINDING | 8 | 123 | 1.164e-07 | 5.149e-06 |
| 22 | TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS | 19 | 992 | 1.451e-07 | 6.126e-06 |
| 23 | PHOSPHATIDYLINOSITOL PHOSPHATE KINASE ACTIVITY | 4 | 16 | 7.975e-07 | 3.221e-05 |
| 24 | RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY | 9 | 228 | 1.275e-06 | 4.935e-05 |
| 25 | PROTEIN KINASE ACTIVITY | 13 | 640 | 9.11e-06 | 0.0003348 |
| 26 | ENZYME REGULATOR ACTIVITY | 16 | 959 | 9.37e-06 | 0.0003348 |
| 27 | GROWTH FACTOR ACTIVITY | 7 | 160 | 1.05e-05 | 0.0003614 |
| 28 | PHOSPHATASE BINDING | 7 | 162 | 1.139e-05 | 0.0003779 |
| 29 | GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY | 9 | 303 | 1.286e-05 | 0.0004121 |
| 30 | PROTEIN TYROSINE KINASE ACTIVITY | 7 | 176 | 1.95e-05 | 0.0006037 |
| 31 | PROTEIN PHOSPHATASE BINDING | 6 | 120 | 2.178e-05 | 0.0006528 |
| 32 | GLUCOCORTICOID RECEPTOR BINDING | 3 | 14 | 3.525e-05 | 0.001023 |
| 33 | PEPTIDE HORMONE RECEPTOR BINDING | 3 | 17 | 6.518e-05 | 0.001835 |
| 34 | ENZYME INHIBITOR ACTIVITY | 9 | 378 | 7.233e-05 | 0.001976 |
| 35 | RNA POLYMERASE II CORE PROMOTER SEQUENCE SPECIFIC DNA BINDING | 4 | 53 | 0.0001123 | 0.002982 |
| 36 | PROTEIN SERINE THREONINE KINASE INHIBITOR ACTIVITY | 3 | 30 | 0.0003723 | 0.009608 |
| Num | GO | Overlap | Size | P Value | Adj. P Value |
|---|---|---|---|---|---|
| 1 | PHOSPHATIDYLINOSITOL 3 KINASE COMPLEX | 7 | 20 | 2.976e-12 | 1.738e-09 |
| 2 | EXTRACELLULAR SPACE | 24 | 1376 | 1.41e-08 | 4.116e-06 |
| 3 | EXTRINSIC COMPONENT OF MEMBRANE | 11 | 252 | 2.807e-08 | 5.464e-06 |
| 4 | RECEPTOR COMPLEX | 12 | 327 | 4.296e-08 | 6.272e-06 |
| 5 | SIDE OF MEMBRANE | 13 | 428 | 1.03e-07 | 1.203e-05 |
| 6 | TRANSFERASE COMPLEX TRANSFERRING PHOSPHORUS CONTAINING GROUPS | 10 | 237 | 1.71e-07 | 1.483e-05 |
| 7 | EXTERNAL SIDE OF PLASMA MEMBRANE | 10 | 238 | 1.778e-07 | 1.483e-05 |
| 8 | PLASMA MEMBRANE RECEPTOR COMPLEX | 8 | 175 | 1.718e-06 | 0.0001254 |
| 9 | CELL SURFACE | 15 | 757 | 2.348e-06 | 0.0001524 |
| 10 | INTRINSIC COMPONENT OF PLASMA MEMBRANE | 21 | 1649 | 2.066e-05 | 0.001097 |
| 11 | MEMBRANE PROTEIN COMPLEX | 16 | 1020 | 2.009e-05 | 0.001097 |
| 12 | TRANSFERASE COMPLEX | 12 | 703 | 0.0001106 | 0.005384 |
Over-represented Pathway
| Num | Pathway | Pathview | Overlap | Size | P Value | Adj. P Value |
|---|---|---|---|---|---|---|
| 1 | hsa04630_Jak.STAT_signaling_pathway | 93 | 155 | 1.784e-210 | 3.211e-208 | |
| 2 | hsa04151_PI3K_AKT_signaling_pathway | 31 | 351 | 2.429e-31 | 2.187e-29 | |
| 3 | hsa04012_ErbB_signaling_pathway | 15 | 87 | 7.51e-20 | 4.506e-18 | |
| 4 | hsa04380_Osteoclast_differentiation | 16 | 128 | 9.104e-19 | 4.097e-17 | |
| 5 | hsa04660_T_cell_receptor_signaling_pathway | 14 | 108 | 9.152e-17 | 3.083e-15 | |
| 6 | hsa04910_Insulin_signaling_pathway | 15 | 138 | 1.028e-16 | 3.083e-15 | |
| 7 | hsa04062_Chemokine_signaling_pathway | 16 | 189 | 5.133e-16 | 1.32e-14 | |
| 8 | hsa04620_Toll.like_receptor_signaling_pathway | 12 | 102 | 5.378e-14 | 1.21e-12 | |
| 9 | hsa04650_Natural_killer_cell_mediated_cytotoxicity | 13 | 136 | 6.988e-14 | 1.398e-12 | |
| 10 | hsa04640_Hematopoietic_cell_lineage | 11 | 88 | 3.219e-13 | 5.795e-12 | |
| 11 | hsa04662_B_cell_receptor_signaling_pathway | 10 | 75 | 2.075e-12 | 3.396e-11 | |
| 12 | hsa04664_Fc_epsilon_RI_signaling_pathway | 10 | 79 | 3.552e-12 | 5.328e-11 | |
| 13 | hsa04510_Focal_adhesion | 13 | 200 | 1.001e-11 | 1.387e-10 | |
| 14 | hsa04210_Apoptosis | 10 | 89 | 1.207e-11 | 1.551e-10 | |
| 15 | hsa04722_Neurotrophin_signaling_pathway | 11 | 127 | 1.928e-11 | 2.313e-10 | |
| 16 | hsa04973_Carbohydrate_digestion_and_absorption | 8 | 44 | 2.711e-11 | 3.05e-10 | |
| 17 | hsa04150_mTOR_signaling_pathway | 8 | 52 | 1.116e-10 | 1.182e-09 | |
| 18 | hsa04960_Aldosterone.regulated_sodium_reabsorption | 7 | 42 | 9.525e-10 | 9.525e-09 | |
| 19 | hsa04370_VEGF_signaling_pathway | 8 | 76 | 2.551e-09 | 2.417e-08 | |
| 20 | hsa04914_Progesterone.mediated_oocyte_maturation | 8 | 87 | 7.58e-09 | 6.822e-08 | |
| 21 | hsa04666_Fc_gamma_R.mediated_phagocytosis | 8 | 95 | 1.529e-08 | 1.311e-07 | |
| 22 | hsa04920_Adipocytokine_signaling_pathway | 7 | 68 | 3.1e-08 | 2.536e-07 | |
| 23 | hsa04670_Leukocyte_transendothelial_migration | 8 | 117 | 7.886e-08 | 6.098e-07 | |
| 24 | hsa04070_Phosphatidylinositol_signaling_system | 7 | 78 | 8.131e-08 | 6.098e-07 | |
| 25 | hsa04014_Ras_signaling_pathway | 10 | 236 | 1.644e-07 | 1.184e-06 | |
| 26 | hsa04810_Regulation_of_actin_cytoskeleton | 9 | 214 | 7.525e-07 | 5.209e-06 | |
| 27 | hsa04110_Cell_cycle | 6 | 128 | 3.138e-05 | 0.0002092 | |
| 28 | hsa04310_Wnt_signaling_pathway | 6 | 151 | 7.902e-05 | 0.000508 | |
| 29 | hsa04672_Intestinal_immune_network_for_IgA_production | 4 | 49 | 8.245e-05 | 0.0005118 | |
| 30 | hsa00562_Inositol_phosphate_metabolism | 4 | 57 | 0.0001494 | 0.0008962 | |
| 31 | hsa04120_Ubiquitin_mediated_proteolysis | 5 | 139 | 0.0005044 | 0.002929 | |
| 32 | hsa04350_TGF.beta_signaling_pathway | 4 | 85 | 0.0006926 | 0.003896 | |
| 33 | hsa04144_Endocytosis | 5 | 203 | 0.002711 | 0.01479 | |
| 34 | hsa04115_p53_signaling_pathway | 3 | 69 | 0.00421 | 0.02229 | |
| 35 | hsa04622_RIG.I.like_receptor_signaling_pathway | 3 | 71 | 0.004562 | 0.02346 | |
| 36 | hsa04390_Hippo_signaling_pathway | 4 | 154 | 0.00603 | 0.02973 | |
| 37 | hsa04320_Dorso.ventral_axis_formation | 2 | 25 | 0.006111 | 0.02973 | |
| 38 | hsa04330_Notch_signaling_pathway | 2 | 47 | 0.0206 | 0.09757 | |
| 39 | hsa04010_MAPK_signaling_pathway | 4 | 268 | 0.03768 | 0.1739 | |
| 40 | hsa04720_Long.term_potentiation | 2 | 70 | 0.04294 | 0.1932 | |
| 41 | hsa04520_Adherens_junction | 2 | 73 | 0.04631 | 0.2033 | |
| 42 | hsa04540_Gap_junction | 2 | 90 | 0.06708 | 0.2875 | |
| 43 | hsa04912_GnRH_signaling_pathway | 2 | 101 | 0.08187 | 0.3349 | |
| 44 | hsa04916_Melanogenesis | 2 | 101 | 0.08187 | 0.3349 |
lncRNA-mediated sponge
| Num | lncRNA | miRNAs | miRNAs count | Gene | Sponge regulatory network | lncRNA log2FC | lncRNA pvalue | Gene log2FC | Gene pvalue | lncRNA-gene Pearson correlation |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | AC009950.2 | hsa-miR-148b-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-20a-3p;hsa-miR-24-1-5p;hsa-miR-29a-5p;hsa-miR-301a-3p;hsa-miR-590-5p;hsa-miR-592;hsa-miR-93-3p | 10 | IL6ST | Sponge network | 1.647 | 0.43083 | -0.266 | 0.81784 | 0.564 |
| 2 | AC007743.1 | hsa-let-7a-3p;hsa-let-7f-2-3p;hsa-miR-148b-5p;hsa-miR-155-5p;hsa-miR-16-2-3p;hsa-miR-200c-3p;hsa-miR-24-1-5p;hsa-miR-26b-5p;hsa-miR-32-3p;hsa-miR-33b-5p;hsa-miR-429;hsa-miR-590-5p | 12 | IL6ST | Sponge network | -4.571 | 0.01323 | -0.266 | 0.81784 | 0.522 |
| 3 | ACTA2-AS1 |
hsa-let-7a-3p;hsa-let-7f-2-3p;hsa-miR-148b-5p;hsa-miR-155-5p;hsa-miR-16-2-3p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-26b-5p;hsa-miR-301a-3p;hsa-miR-33a-3p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-590-3p;hsa-miR-93-3p | 16 | IL6ST | Sponge network | -6.142 | 0.00223 | -0.266 | 0.81784 | 0.492 |
| 4 | MAGI2-AS3 |
hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-224-5p;hsa-miR-33a-3p;hsa-miR-590-3p;hsa-miR-92a-3p;hsa-miR-93-3p;hsa-miR-93-5p | 14 | SPRED1 | Sponge network | -4.563 | 0 | -1.208 | 0.0043 | 0.489 |
| 5 | DNM3OS |
hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-224-5p;hsa-miR-33a-3p;hsa-miR-590-3p;hsa-miR-93-3p;hsa-miR-93-5p | 13 | SPRED1 | Sponge network | -3.933 | 0.00059 | -1.208 | 0.0043 | 0.487 |
| 6 | RP11-819C21.1 | hsa-let-7a-3p;hsa-miR-148b-5p;hsa-miR-16-2-3p;hsa-miR-20a-3p;hsa-miR-26b-5p;hsa-miR-28-3p;hsa-miR-30b-5p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-374a-3p;hsa-miR-590-3p;hsa-miR-7-1-3p | 12 | IL6ST | Sponge network | -1.571 | 0.00379 | -0.266 | 0.81784 | 0.485 |
| 7 | EMX2OS |
hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-330-3p;hsa-miR-33a-3p;hsa-miR-3614-5p;hsa-miR-421;hsa-miR-944 | 18 | PRLR | Sponge network | -6.205 | 0.00015 | -5.28 | 0.00088 | 0.479 |
| 8 | HAND2-AS1 |
hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-320b;hsa-miR-330-3p;hsa-miR-33a-3p;hsa-miR-3614-5p;hsa-miR-421;hsa-miR-582-5p;hsa-miR-944 | 20 | PRLR | Sponge network | -7.871 | 0 | -5.28 | 0.00088 | 0.478 |
| 9 | AC002480.3 | hsa-let-7b-5p;hsa-miR-106a-5p;hsa-miR-130b-5p;hsa-miR-15b-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-200a-3p;hsa-miR-20b-5p;hsa-miR-3065-5p;hsa-miR-33a-3p;hsa-miR-378a-3p;hsa-miR-93-5p | 12 | CCND2 | Sponge network | -0.418 | 0.70767 | -2.811 | 0.0014 | 0.477 |
| 10 | ACTA2-AS1 |
hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-224-5p;hsa-miR-33a-3p;hsa-miR-590-3p;hsa-miR-93-3p | 12 | SPRED1 | Sponge network | -6.142 | 0.00223 | -1.208 | 0.0043 | 0.464 |
| 11 | C1RL-AS1 |
hsa-miR-148b-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-20a-3p;hsa-miR-301a-3p;hsa-miR-362-3p;hsa-miR-362-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-93-3p | 10 | IL6ST | Sponge network | -0.784 | 0.21481 | -0.266 | 0.81784 | 0.46 |
| 12 | MAGI2-AS3 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-142-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-3065-5p;hsa-miR-362-3p;hsa-miR-93-5p | 10 | AKT3 | Sponge network | -4.563 | 0 | -3.327 | 1.0E-5 | 0.454 |
| 13 | RP11-760H22.2 | hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-32-3p;hsa-miR-320b;hsa-miR-9-3p;hsa-miR-944 | 14 | PRLR | Sponge network | -3.418 | 0.00912 | -5.28 | 0.00088 | 0.447 |
| 14 | RP11-166D19.1 |
hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-429;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-9-5p;hsa-miR-944 | 16 | LIFR | Sponge network | -4.209 | 2.0E-5 | -4.51 | 1.0E-5 | 0.442 |
| 15 | RP11-166D19.1 |
hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-224-5p;hsa-miR-33a-3p;hsa-miR-590-3p;hsa-miR-92a-3p;hsa-miR-93-3p | 13 | SPRED1 | Sponge network | -4.209 | 2.0E-5 | -1.208 | 0.0043 | 0.436 |
| 16 | RP11-284N8.3 |
hsa-miR-148b-5p;hsa-miR-16-2-3p;hsa-miR-182-5p;hsa-miR-20a-3p;hsa-miR-301a-3p;hsa-miR-335-3p;hsa-miR-335-5p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-590-5p;hsa-miR-93-3p | 11 | IL6ST | Sponge network | -0.845 | 0.52848 | -0.266 | 0.81784 | 0.423 |
| 17 | NR2F2-AS1 |
hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-3614-5p;hsa-miR-9-3p;hsa-miR-944 | 13 | PRLR | Sponge network | -3.785 | 0.00281 | -5.28 | 0.00088 | 0.417 |
| 18 | LINC00284 |
hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-155-5p;hsa-miR-15b-3p;hsa-miR-21-3p;hsa-miR-330-3p;hsa-miR-330-5p;hsa-miR-590-3p;hsa-miR-708-3p;hsa-miR-708-5p;hsa-miR-944 | 12 | SPRY3 | Sponge network | -5.478 | 0.02716 | -0.618 | 0.35993 | 0.417 |
| 19 | LINC00284 |
hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-32-3p;hsa-miR-330-3p;hsa-miR-944 | 14 | PRLR | Sponge network | -5.478 | 0.02716 | -5.28 | 0.00088 | 0.41 |
| 20 | MAGI2-AS3 |
hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-3065-5p;hsa-miR-429;hsa-miR-590-3p;hsa-miR-629-3p | 14 | LIFR | Sponge network | -4.563 | 0 | -4.51 | 1.0E-5 | 0.403 |
| 21 | NR2F1-AS1 |
hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-224-5p;hsa-miR-590-3p;hsa-miR-92a-3p | 10 | SPRED1 | Sponge network | -2.961 | 0.00154 | -1.208 | 0.0043 | 0.4 |
| 22 | RP11-464C19.3 | hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-20b-5p;hsa-miR-93-5p | 10 | CCND2 | Sponge network | -6.257 | 0.01732 | -2.811 | 0.0014 | 0.397 |
| 23 | AC005682.5 | hsa-let-7b-5p;hsa-miR-106a-5p;hsa-miR-10a-3p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-15b-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-200a-3p;hsa-miR-20b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-3065-5p | 14 | CCND2 | Sponge network | -2.193 | 0.07184 | -2.811 | 0.0014 | 0.394 |
| 24 | FAM66C |
hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-33a-3p;hsa-miR-3614-5p | 14 | PRLR | Sponge network | -2.927 | 0.00012 | -5.28 | 0.00088 | 0.392 |
| 25 | MAGI2-AS3 |
hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-320b;hsa-miR-33a-3p;hsa-miR-3614-5p;hsa-miR-421;hsa-miR-9-3p | 18 | PRLR | Sponge network | -4.563 | 0 | -5.28 | 0.00088 | 0.391 |
| 26 | RP11-401P9.4 |
hsa-let-7f-2-3p;hsa-miR-141-3p;hsa-miR-142-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-361-3p;hsa-miR-452-3p | 10 | SPRY4 | Sponge network | -3.793 | 0.00144 | -1.479 | 0.04303 | 0.39 |
| 27 | MLLT4-AS1 | hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-miR-1271-5p;hsa-miR-142-3p;hsa-miR-146a-5p;hsa-miR-155-5p;hsa-miR-15b-3p;hsa-miR-21-3p;hsa-miR-296-5p;hsa-miR-330-3p;hsa-miR-944 | 12 | SPRY3 | Sponge network | -0.411 | 0.60301 | -0.618 | 0.35993 | 0.386 |
| 28 | HAND2-AS1 |
hsa-let-7f-1-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-429;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-944 | 13 | LIFR | Sponge network | -7.871 | 0 | -4.51 | 1.0E-5 | 0.386 |
| 29 | RP11-244O19.1 | hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15b-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-200a-3p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-30d-3p;hsa-miR-324-3p;hsa-miR-93-5p | 16 | CCND2 | Sponge network | -1.318 | 0.0924 | -2.811 | 0.0014 | 0.383 |
| 30 | RP4-798P15.3 |
hsa-let-7a-3p;hsa-let-7f-2-3p;hsa-miR-148b-5p;hsa-miR-155-5p;hsa-miR-16-2-3p;hsa-miR-186-5p;hsa-miR-20a-3p;hsa-miR-301a-3p;hsa-miR-30b-5p;hsa-miR-30e-5p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-93-3p | 15 | IL6ST | Sponge network | -0.893 | 0.37877 | -0.266 | 0.81784 | 0.379 |
| 31 | NR2F2-AS1 |
hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-944 | 14 | LIFR | Sponge network | -3.785 | 0.00281 | -4.51 | 1.0E-5 | 0.379 |
| 32 | MEG3 |
hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-224-5p;hsa-miR-33a-3p;hsa-miR-93-3p;hsa-miR-93-5p | 12 | SPRED1 | Sponge network | -3.613 | 0.00075 | -1.208 | 0.0043 | 0.379 |
| 33 | RP11-554A11.4 |
hsa-let-7d-5p;hsa-miR-103a-2-5p;hsa-miR-148b-5p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-32-3p;hsa-miR-320b;hsa-miR-33a-3p;hsa-miR-421 | 11 | PRLR | Sponge network | -5.361 | 2.0E-5 | -5.28 | 0.00088 | 0.376 |
| 34 | RP11-567M16.1 |
hsa-miR-1301-3p;hsa-miR-148b-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-29a-5p;hsa-miR-29b-2-5p;hsa-miR-301a-3p;hsa-miR-335-3p;hsa-miR-590-5p;hsa-miR-592;hsa-miR-93-3p | 12 | IL6ST | Sponge network | -2.638 | 0.21408 | -0.266 | 0.81784 | 0.375 |
| 35 | MAGI2-AS3 |
hsa-miR-130b-5p;hsa-miR-16-1-3p;hsa-miR-16-2-3p;hsa-miR-33a-3p;hsa-miR-342-3p;hsa-miR-362-3p;hsa-miR-429;hsa-miR-590-3p;hsa-miR-660-5p;hsa-miR-7-1-3p | 10 | LEPR | Sponge network | -4.563 | 0 | -3.723 | 0 | 0.375 |
| 36 | DIO3OS |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-200a-3p;hsa-miR-20b-5p;hsa-miR-324-3p;hsa-miR-3607-3p;hsa-miR-378a-3p;hsa-miR-550a-5p;hsa-miR-660-5p | 19 | CCND2 | Sponge network | -4.295 | 0.00689 | -2.811 | 0.0014 | 0.374 |
| 37 | MIR143HG |
hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-224-5p;hsa-miR-33a-3p;hsa-miR-34a-5p;hsa-miR-590-3p;hsa-miR-92a-3p;hsa-miR-93-3p;hsa-miR-93-5p | 15 | SPRED1 | Sponge network | -6.51 | 0 | -1.208 | 0.0043 | 0.373 |
| 38 | RASSF8-AS1 |
hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-205-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-944 | 12 | LIFR | Sponge network | -2.562 | 0.00163 | -4.51 | 1.0E-5 | 0.373 |
| 39 | PCED1B-AS1 | hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-3065-5p;hsa-miR-30d-3p;hsa-miR-429;hsa-miR-93-5p;hsa-miR-96-5p | 10 | CCND2 | Sponge network | 0.764 | 0.37397 | -2.811 | 0.0014 | 0.371 |
| 40 | CTB-92J24.3 |
hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-301a-3p;hsa-miR-33a-3p;hsa-miR-3614-5p;hsa-miR-944 | 14 | PRLR | Sponge network | -7.226 | 0.0046 | -5.28 | 0.00088 | 0.371 |
| 41 | RP11-627G23.1 | hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-330-3p;hsa-miR-33a-3p;hsa-miR-421;hsa-miR-9-3p;hsa-miR-9-5p | 12 | PRLR | Sponge network | -4.055 | 0.12629 | -5.28 | 0.00088 | 0.363 |
| 42 | RP11-116O18.1 |
hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-944 | 13 | LIFR | Sponge network | -5.007 | 0.06008 | -4.51 | 1.0E-5 | 0.361 |
| 43 | RP11-150O12.3 |
hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-320b;hsa-miR-33a-3p;hsa-miR-34c-5p;hsa-miR-9-3p | 14 | PRLR | Sponge network | -4.03 | 0.14448 | -5.28 | 0.00088 | 0.36 |
| 44 | AC003090.1 |
hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-320b;hsa-miR-320c;hsa-miR-330-3p;hsa-miR-582-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p | 15 | PIK3R1 | Sponge network | -7.817 | 0.00161 | -1.854 | 0.01274 | 0.358 |
| 45 | DNM3OS |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-142-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-3065-5p;hsa-miR-502-3p;hsa-miR-93-5p | 10 | AKT3 | Sponge network | -3.933 | 0.00059 | -3.327 | 1.0E-5 | 0.354 |
| 46 | CTC-297N7.9 | hsa-let-7d-5p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-301a-3p;hsa-miR-330-3p;hsa-miR-9-5p | 10 | PRLR | Sponge network | -3.463 | 0.00542 | -5.28 | 0.00088 | 0.353 |
| 47 | AC141928.1 |
hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-330-3p;hsa-miR-3614-5p | 11 | PRLR | Sponge network | -4.805 | 0.00102 | -5.28 | 0.00088 | 0.352 |
| 48 | CTA-109P11.4 | hsa-let-7d-5p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-301a-3p;hsa-miR-330-3p;hsa-miR-421 | 12 | PRLR | Sponge network | -7.746 | 0.00804 | -5.28 | 0.00088 | 0.347 |
| 49 | RP11-344E13.3 |
hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-224-5p;hsa-miR-34a-5p;hsa-miR-590-3p;hsa-miR-93-3p;hsa-miR-93-5p | 12 | SPRED1 | Sponge network | -4.307 | 3.0E-5 | -1.208 | 0.0043 | 0.346 |
| 50 | RP11-116O18.1 |
hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-320b;hsa-miR-944 | 14 | PRLR | Sponge network | -5.007 | 0.06008 | -5.28 | 0.00088 | 0.342 |
| 51 | TPT1-AS1 | hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-590-3p;hsa-miR-629-3p | 11 | LIFR | Sponge network | -1.055 | 0.00828 | -4.51 | 1.0E-5 | 0.342 |
| 52 | RP11-822E23.8 |
hsa-let-7a-3p;hsa-miR-1301-3p;hsa-miR-148b-5p;hsa-miR-155-5p;hsa-miR-16-2-3p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-335-3p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-93-3p | 11 | IL6ST | Sponge network | -8.351 | 0.00374 | -0.266 | 0.81784 | 0.341 |
| 53 | RP11-166D19.1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-200a-3p;hsa-miR-20b-5p;hsa-miR-224-3p;hsa-miR-30d-3p;hsa-miR-324-3p;hsa-miR-33a-3p;hsa-miR-3607-3p;hsa-miR-378a-3p;hsa-miR-429;hsa-miR-550a-5p;hsa-miR-96-5p | 23 | CCND2 | Sponge network | -4.209 | 2.0E-5 | -2.811 | 0.0014 | 0.339 |
| 54 | RP11-439M11.1 | hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-20b-5p;hsa-miR-324-3p;hsa-miR-660-5p | 13 | CCND2 | Sponge network | -2.662 | 0.21003 | -2.811 | 0.0014 | 0.337 |
| 55 | DNM3OS |
hsa-let-7f-2-3p;hsa-miR-1301-3p;hsa-miR-148b-5p;hsa-miR-155-5p;hsa-miR-16-2-3p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-33a-3p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-429;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-592;hsa-miR-7-1-3p;hsa-miR-93-3p | 20 | IL6ST | Sponge network | -3.933 | 0.00059 | -0.266 | 0.81784 | 0.337 |
| 56 | LINC00996 | hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-10a-3p;hsa-miR-130b-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-93-5p | 12 | CCND2 | Sponge network | 0.84 | 0.43075 | -2.811 | 0.0014 | 0.333 |
| 57 | FAM66C |
hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-429;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p | 13 | LIFR | Sponge network | -2.927 | 0.00012 | -4.51 | 1.0E-5 | 0.331 |
| 58 | ZNF667-AS1 |
hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-224-5p;hsa-miR-93-5p | 10 | SPRED1 | Sponge network | -4.019 | 0.00137 | -1.208 | 0.0043 | 0.331 |
| 59 | CTD-2334D19.1 | hsa-miR-106b-5p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-224-5p;hsa-miR-590-3p;hsa-miR-93-5p | 10 | SPRED1 | Sponge network | -4.489 | 0.03789 | -1.208 | 0.0043 | 0.329 |
| 60 | RP11-263K19.4 | hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-205-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-629-3p | 10 | LIFR | Sponge network | -1.558 | 0.01688 | -4.51 | 1.0E-5 | 0.327 |
| 61 | LINC00284 |
hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-944 | 14 | LIFR | Sponge network | -5.478 | 0.02716 | -4.51 | 1.0E-5 | 0.326 |
| 62 | RP11-822E23.8 |
hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-93-3p;hsa-miR-93-5p | 10 | SPRED1 | Sponge network | -8.351 | 0.00374 | -1.208 | 0.0043 | 0.325 |
| 63 | PWAR6 |
hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-1271-5p;hsa-miR-142-3p;hsa-miR-146a-5p;hsa-miR-155-5p;hsa-miR-15b-3p;hsa-miR-21-3p;hsa-miR-330-3p;hsa-miR-330-5p;hsa-miR-944 | 11 | SPRY3 | Sponge network | -3.15 | 0.0082 | -0.618 | 0.35993 | 0.323 |
| 64 | MIR497HG |
hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-301a-3p;hsa-miR-33a-3p | 12 | PRLR | Sponge network | -6.146 | 0.00024 | -5.28 | 0.00088 | 0.319 |
| 65 | PWAR6 |
hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-142-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-330-3p;hsa-miR-944 | 11 | PRLR | Sponge network | -3.15 | 0.0082 | -5.28 | 0.00088 | 0.319 |
| 66 | MEG3 |
hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-130b-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-320b;hsa-miR-330-3p;hsa-miR-33a-3p;hsa-miR-3614-5p;hsa-miR-421;hsa-miR-944 | 14 | PRLR | Sponge network | -3.613 | 0.00075 | -5.28 | 0.00088 | 0.318 |
| 67 | RP11-359B12.2 | hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p | 10 | LIFR | Sponge network | -2.094 | 0.00033 | -4.51 | 1.0E-5 | 0.317 |
| 68 | AP001055.6 | hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-3065-3p;hsa-miR-550a-5p | 11 | CCND2 | Sponge network | -1.255 | 0.1158 | -2.811 | 0.0014 | 0.316 |
| 69 | MAGI2-AS3 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-200a-3p;hsa-miR-20b-5p;hsa-miR-224-3p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-30d-3p;hsa-miR-33a-3p;hsa-miR-3607-3p;hsa-miR-378a-3p;hsa-miR-429;hsa-miR-501-5p;hsa-miR-660-5p;hsa-miR-9-3p;hsa-miR-93-5p | 26 | CCND2 | Sponge network | -4.563 | 0 | -2.811 | 0.0014 | 0.315 |
| 70 | PGM5-AS1 |
hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-301a-3p;hsa-miR-33a-3p | 11 | PRLR | Sponge network | -14.107 | 0 | -5.28 | 0.00088 | 0.315 |
| 71 | RP11-130L8.1 |
hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-944 | 11 | PRLR | Sponge network | -4.329 | 1.0E-5 | -5.28 | 0.00088 | 0.314 |
| 72 | RP11-284N8.3 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-16-2-3p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-200a-3p;hsa-miR-3065-5p;hsa-miR-324-3p;hsa-miR-93-5p;hsa-miR-96-5p | 12 | CCND2 | Sponge network | -0.845 | 0.52848 | -2.811 | 0.0014 | 0.313 |
| 73 | EMX2OS |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-miR-1271-5p;hsa-miR-155-5p;hsa-miR-15b-3p;hsa-miR-21-3p;hsa-miR-330-3p;hsa-miR-330-5p;hsa-miR-590-3p;hsa-miR-944 | 11 | SPRY3 | Sponge network | -6.205 | 0.00015 | -0.618 | 0.35993 | 0.312 |
| 74 | MAGI2-AS3 |
hsa-let-7a-3p;hsa-let-7f-2-3p;hsa-miR-1301-3p;hsa-miR-148b-5p;hsa-miR-155-5p;hsa-miR-16-2-3p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-301a-3p;hsa-miR-30b-5p;hsa-miR-30e-5p;hsa-miR-32-3p;hsa-miR-335-3p;hsa-miR-33a-3p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-362-3p;hsa-miR-362-5p;hsa-miR-429;hsa-miR-505-3p;hsa-miR-590-3p;hsa-miR-592;hsa-miR-7-1-3p;hsa-miR-93-3p | 26 | IL6ST | Sponge network | -4.563 | 0 | -0.266 | 0.81784 | 0.312 |
| 75 | RP11-166D19.1 |
hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-33a-3p;hsa-miR-3614-5p;hsa-miR-9-5p;hsa-miR-944 | 17 | PRLR | Sponge network | -4.209 | 2.0E-5 | -5.28 | 0.00088 | 0.309 |
| 76 | RP11-757G1.6 | hsa-let-7f-1-3p;hsa-miR-205-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-590-3p;hsa-miR-629-3p;hsa-miR-944 | 11 | LIFR | Sponge network | -2.705 | 0.04664 | -4.51 | 1.0E-5 | 0.309 |
| 77 | RP11-150O12.3 |
hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-629-3p | 11 | LIFR | Sponge network | -4.03 | 0.14448 | -4.51 | 1.0E-5 | 0.308 |
| 78 | MIR497HG |
hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-320c;hsa-miR-584-5p;hsa-miR-590-5p;hsa-miR-629-3p | 13 | PIK3R1 | Sponge network | -6.146 | 0.00024 | -1.854 | 0.01274 | 0.307 |
| 79 | ACTA2-AS1 |
hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-1271-5p;hsa-miR-142-3p;hsa-miR-146a-5p;hsa-miR-155-5p;hsa-miR-15b-3p;hsa-miR-21-3p;hsa-miR-296-5p;hsa-miR-590-3p;hsa-miR-708-5p;hsa-miR-944 | 12 | SPRY3 | Sponge network | -6.142 | 0.00223 | -0.618 | 0.35993 | 0.306 |
| 80 | RASSF8-AS1 |
hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-22-5p;hsa-miR-33a-3p;hsa-miR-944 | 10 | PRLR | Sponge network | -2.562 | 0.00163 | -5.28 | 0.00088 | 0.305 |
| 81 | A1BG-AS1 | hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-20b-5p;hsa-miR-224-3p;hsa-miR-3065-3p | 13 | CCND2 | Sponge network | -1.791 | 0.08754 | -2.811 | 0.0014 | 0.305 |
| 82 | RP11-774O3.3 |
hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-32-3p;hsa-miR-320b;hsa-miR-320c;hsa-miR-330-3p;hsa-miR-335-3p;hsa-miR-590-3p;hsa-miR-629-3p | 14 | PIK3R1 | Sponge network | -1.989 | 0.00136 | -1.854 | 0.01274 | 0.303 |
| 83 | MIR143HG |
hsa-miR-107;hsa-miR-130b-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-25-3p;hsa-miR-32-5p;hsa-miR-324-5p;hsa-miR-363-3p;hsa-miR-429;hsa-miR-576-5p;hsa-miR-940 | 14 | SOCS2 | Sponge network | -6.51 | 0 | -3.753 | 1.0E-5 | 0.303 |
| 84 | NR2F1-AS1 |
hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-320b;hsa-miR-330-3p;hsa-miR-3614-5p | 13 | PRLR | Sponge network | -2.961 | 0.00154 | -5.28 | 0.00088 | 0.303 |
| 85 | RP11-890B15.2 | hsa-miR-106a-5p;hsa-miR-10a-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-182-5p;hsa-miR-191-5p;hsa-miR-20b-5p;hsa-miR-28-5p;hsa-miR-30d-3p;hsa-miR-93-5p | 10 | CCND2 | Sponge network | 1.76 | 0.42927 | -2.811 | 0.0014 | 0.302 |
| 86 | SNHG14 |
hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-142-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-330-3p | 10 | PRLR | Sponge network | -3.108 | 0.00332 | -5.28 | 0.00088 | 0.302 |
| 87 | RP11-536K7.3 | hsa-miR-106a-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-200a-3p;hsa-miR-20b-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-30d-3p;hsa-miR-93-5p | 16 | CCND2 | Sponge network | -1.796 | 0.15215 | -2.811 | 0.0014 | 0.302 |
| 88 | GAS6-AS2 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-200a-3p;hsa-miR-20b-5p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-324-3p;hsa-miR-429 | 16 | CCND2 | Sponge network | -1.941 | 0.0681 | -2.811 | 0.0014 | 0.301 |
| 89 | AC141928.1 |
hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-629-3p | 11 | LIFR | Sponge network | -4.805 | 0.00102 | -4.51 | 1.0E-5 | 0.301 |
| 90 | RP11-389C8.2 |
hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-33a-3p;hsa-miR-93-5p | 10 | SPRED1 | Sponge network | -3.089 | 2.0E-5 | -1.208 | 0.0043 | 0.301 |
| 91 | RP11-13K12.1 |
hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130a-3p;hsa-miR-142-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-330-3p;hsa-miR-944 | 12 | PRLR | Sponge network | -5.093 | 0.01151 | -5.28 | 0.00088 | 0.298 |
| 92 | TRHDE-AS1 |
hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-32-3p;hsa-miR-320b;hsa-miR-330-3p;hsa-miR-33a-3p;hsa-miR-3614-5p;hsa-miR-421;hsa-miR-582-5p | 17 | PRLR | Sponge network | -6.205 | 0.01165 | -5.28 | 0.00088 | 0.297 |
| 93 | RP11-389C8.2 |
hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-22-5p;hsa-miR-3065-5p;hsa-miR-330-3p;hsa-miR-335-3p;hsa-miR-629-3p | 11 | PIK3R1 | Sponge network | -3.089 | 2.0E-5 | -1.854 | 0.01274 | 0.297 |
| 94 | RP11-13K12.1 |
hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-629-3p;hsa-miR-944 | 12 | LIFR | Sponge network | -5.093 | 0.01151 | -4.51 | 1.0E-5 | 0.295 |
| 95 | MAGI2-AS3 |
hsa-miR-107;hsa-miR-130b-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-25-3p;hsa-miR-32-5p;hsa-miR-324-5p;hsa-miR-362-5p;hsa-miR-363-3p;hsa-miR-429;hsa-miR-576-5p;hsa-miR-940 | 15 | SOCS2 | Sponge network | -4.563 | 0 | -3.753 | 1.0E-5 | 0.295 |
| 96 | RP11-890B15.3 |
hsa-miR-1301-3p;hsa-miR-148b-5p;hsa-miR-155-5p;hsa-miR-16-2-3p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-28-3p;hsa-miR-301a-3p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-7-1-3p | 12 | IL6ST | Sponge network | -2.059 | 0.00641 | -0.266 | 0.81784 | 0.295 |
| 97 | RP11-389C8.2 |
hsa-let-7b-5p;hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-200a-3p;hsa-miR-224-3p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-33a-3p;hsa-miR-429;hsa-miR-550a-5p;hsa-miR-93-5p | 21 | CCND2 | Sponge network | -3.089 | 2.0E-5 | -2.811 | 0.0014 | 0.293 |
| 98 | HOTAIRM1 | hsa-miR-106a-5p;hsa-miR-10a-3p;hsa-miR-130b-5p;hsa-miR-15b-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-200a-3p;hsa-miR-20b-5p;hsa-miR-28-5p;hsa-miR-30d-3p | 11 | CCND2 | Sponge network | 0.285 | 0.72086 | -2.811 | 0.0014 | 0.293 |
| 99 | NR2F1-AS1 |
hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-320b;hsa-miR-330-3p;hsa-miR-590-3p;hsa-miR-629-3p | 12 | PIK3R1 | Sponge network | -2.961 | 0.00154 | -1.854 | 0.01274 | 0.292 |
| 100 | HAND2-AS1 |
hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-224-5p;hsa-miR-33a-3p;hsa-miR-34a-5p;hsa-miR-590-3p;hsa-miR-92a-3p;hsa-miR-93-3p;hsa-miR-93-5p | 15 | SPRED1 | Sponge network | -7.871 | 0 | -1.208 | 0.0043 | 0.292 |
| 101 | ACTA2-AS1 |
hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130a-3p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-301a-3p;hsa-miR-33a-3p;hsa-miR-3614-5p;hsa-miR-944 | 17 | PRLR | Sponge network | -6.142 | 0.00223 | -5.28 | 0.00088 | 0.291 |
| 102 | RP11-554A11.4 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-20b-5p;hsa-miR-3065-3p;hsa-miR-324-3p;hsa-miR-33a-3p | 14 | CCND2 | Sponge network | -5.361 | 2.0E-5 | -2.811 | 0.0014 | 0.29 |
| 103 | NR2F2-AS1 |
hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-1271-5p;hsa-miR-142-3p;hsa-miR-155-5p;hsa-miR-15b-3p;hsa-miR-21-3p;hsa-miR-330-5p;hsa-miR-590-3p;hsa-miR-708-3p;hsa-miR-708-5p;hsa-miR-944 | 12 | SPRY3 | Sponge network | -3.785 | 0.00281 | -0.618 | 0.35993 | 0.288 |
| 104 | LINC00861 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-200a-3p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-33a-3p;hsa-miR-429;hsa-miR-501-5p;hsa-miR-96-5p | 12 | CCND2 | Sponge network | 0.999 | 0.45301 | -2.811 | 0.0014 | 0.287 |
| 105 | LINC00426 | hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-15b-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-9-3p;hsa-miR-93-5p;hsa-miR-96-5p | 12 | CCND2 | Sponge network | 0.65 | 0.52974 | -2.811 | 0.0014 | 0.287 |
| 106 | AC007277.3 | hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-205-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-590-3p | 10 | LIFR | Sponge network | -5.22 | 0.0188 | -4.51 | 1.0E-5 | 0.287 |
| 107 | WT1-AS |
hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-33a-3p;hsa-miR-374b-3p;hsa-miR-421;hsa-miR-9-3p;hsa-miR-9-5p;hsa-miR-944 | 20 | PRLR | Sponge network | -6.875 | 2.0E-5 | -5.28 | 0.00088 | 0.286 |
| 108 | RP11-747H7.3 |
hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-148b-5p;hsa-miR-20a-3p;hsa-miR-32-3p;hsa-miR-374b-3p;hsa-miR-421;hsa-miR-9-3p;hsa-miR-9-5p;hsa-miR-944 | 12 | PRLR | Sponge network | -0.36 | 0.74172 | -5.28 | 0.00088 | 0.286 |
| 109 | RP11-567M16.1 |
hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-29b-3p;hsa-miR-320b;hsa-miR-330-3p;hsa-miR-335-3p;hsa-miR-590-5p;hsa-miR-629-3p | 11 | PIK3R1 | Sponge network | -2.638 | 0.21408 | -1.854 | 0.01274 | 0.286 |
| 110 | DNM3OS |
hsa-miR-1301-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-3065-5p;hsa-miR-32-3p;hsa-miR-320b;hsa-miR-320c;hsa-miR-330-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p | 15 | PIK3R1 | Sponge network | -3.933 | 0.00059 | -1.854 | 0.01274 | 0.285 |
| 111 | ADAMTS9-AS1 |
hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-301a-3p;hsa-miR-320b;hsa-miR-3614-5p;hsa-miR-421;hsa-miR-582-5p | 16 | PRLR | Sponge network | -8.573 | 0.00012 | -5.28 | 0.00088 | 0.285 |
| 112 | MIR143HG |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-200a-3p;hsa-miR-20b-5p;hsa-miR-224-3p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-30d-3p;hsa-miR-324-3p;hsa-miR-33a-3p;hsa-miR-3607-3p;hsa-miR-378a-3p;hsa-miR-429;hsa-miR-501-5p;hsa-miR-550a-5p;hsa-miR-93-5p | 26 | CCND2 | Sponge network | -6.51 | 0 | -2.811 | 0.0014 | 0.285 |
| 113 | MIR143HG |
hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-27a-3p;hsa-miR-3065-5p;hsa-miR-429;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p | 14 | LIFR | Sponge network | -6.51 | 0 | -4.51 | 1.0E-5 | 0.284 |
| 114 | LINC00261 |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-miR-1271-5p;hsa-miR-142-3p;hsa-miR-155-5p;hsa-miR-15b-3p;hsa-miR-21-3p;hsa-miR-296-5p;hsa-miR-330-3p;hsa-miR-330-5p;hsa-miR-590-3p;hsa-miR-708-5p | 13 | SPRY3 | Sponge network | -3.398 | 0.26149 | -0.618 | 0.35993 | 0.283 |
| 115 | LINC00284 |
hsa-miR-18a-3p;hsa-miR-19b-3p;hsa-miR-222-5p;hsa-miR-29b-1-5p;hsa-miR-330-3p;hsa-miR-330-5p;hsa-miR-365a-3p;hsa-miR-511-5p;hsa-miR-590-3p;hsa-miR-590-5p | 10 | PIK3R3 | Sponge network | -5.478 | 0.02716 | -0.03 | 0.95933 | 0.283 |
| 116 | RP11-150O12.3 |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-miR-1271-5p;hsa-miR-142-3p;hsa-miR-155-5p;hsa-miR-296-5p;hsa-miR-320b;hsa-miR-330-5p;hsa-miR-708-5p | 10 | SPRY3 | Sponge network | -4.03 | 0.14448 | -0.618 | 0.35993 | 0.283 |
| 117 | ZNF667-AS1 |
hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-301a-3p | 12 | PRLR | Sponge network | -4.019 | 0.00137 | -5.28 | 0.00088 | 0.281 |
| 118 | AC004540.5 |
hsa-let-7a-3p;hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-330-3p;hsa-miR-33a-3p;hsa-miR-34c-5p;hsa-miR-3614-5p | 11 | PRLR | Sponge network | -2.462 | 0.01794 | -5.28 | 0.00088 | 0.28 |
| 119 | RP11-166D19.1 |
hsa-miR-107;hsa-miR-130b-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-25-3p;hsa-miR-32-5p;hsa-miR-363-3p;hsa-miR-429;hsa-miR-576-5p;hsa-miR-940 | 13 | SOCS2 | Sponge network | -4.209 | 2.0E-5 | -3.753 | 1.0E-5 | 0.28 |
| 120 | DNM3OS |
hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-301a-3p;hsa-miR-32-3p;hsa-miR-320b;hsa-miR-330-3p;hsa-miR-33a-3p | 15 | PRLR | Sponge network | -3.933 | 0.00059 | -5.28 | 0.00088 | 0.279 |
| 121 | NR2F1-AS1 |
hsa-miR-18a-3p;hsa-miR-19b-3p;hsa-miR-222-5p;hsa-miR-29b-1-5p;hsa-miR-32-5p;hsa-miR-330-3p;hsa-miR-330-5p;hsa-miR-365a-3p;hsa-miR-511-5p;hsa-miR-590-3p;hsa-miR-92a-3p | 11 | PIK3R3 | Sponge network | -2.961 | 0.00154 | -0.03 | 0.95933 | 0.279 |
| 122 | NR2F2-AS1 |
hsa-miR-106b-5p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-224-5p;hsa-miR-590-3p;hsa-miR-92a-3p;hsa-miR-93-3p;hsa-miR-93-5p | 11 | SPRED1 | Sponge network | -3.785 | 0.00281 | -1.208 | 0.0043 | 0.277 |
| 123 | ADAMTS9-AS1 |
hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-224-5p;hsa-miR-590-3p;hsa-miR-92a-3p;hsa-miR-93-3p;hsa-miR-93-5p | 13 | SPRED1 | Sponge network | -8.573 | 0.00012 | -1.208 | 0.0043 | 0.276 |
| 124 | RP11-389C8.2 |
hsa-let-7a-3p;hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-130b-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-22-5p;hsa-miR-301a-3p;hsa-miR-330-3p;hsa-miR-33a-3p;hsa-miR-421 | 15 | PRLR | Sponge network | -3.089 | 2.0E-5 | -5.28 | 0.00088 | 0.275 |
| 125 | ADAMTS9-AS1 |
hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-429;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-629-3p | 14 | LIFR | Sponge network | -8.573 | 0.00012 | -4.51 | 1.0E-5 | 0.275 |
| 126 | ZNF667-AS1 |
hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-320c;hsa-miR-590-5p;hsa-miR-629-3p | 11 | PIK3R1 | Sponge network | -4.019 | 0.00137 | -1.854 | 0.01274 | 0.273 |
| 127 | RP11-384L8.1 | hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-146a-5p;hsa-miR-155-5p;hsa-miR-21-3p;hsa-miR-330-3p;hsa-miR-330-5p;hsa-miR-590-3p | 10 | SPRY3 | Sponge network | -1.784 | 0.21615 | -0.618 | 0.35993 | 0.271 |
| 128 | MIR143HG |
hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-142-3p;hsa-miR-148b-5p;hsa-miR-15b-3p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-20a-3p;hsa-miR-301a-3p;hsa-miR-330-3p;hsa-miR-33a-3p;hsa-miR-3614-5p | 14 | PRLR | Sponge network | -6.51 | 0 | -5.28 | 0.00088 | 0.267 |
| 129 | MEG3 |
hsa-let-7f-1-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-429;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-944 | 13 | LIFR | Sponge network | -3.613 | 0.00075 | -4.51 | 1.0E-5 | 0.266 |
| 130 | ACTA2-AS1 |
hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-22-5p;hsa-miR-29b-3p;hsa-miR-590-3p | 10 | PIK3R1 | Sponge network | -6.142 | 0.00223 | -1.854 | 0.01274 | 0.264 |
| 131 | ACTA2-AS1 |
hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-590-3p;hsa-miR-944 | 12 | LIFR | Sponge network | -6.142 | 0.00223 | -4.51 | 1.0E-5 | 0.263 |
| 132 | RP11-532F6.3 |
hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-224-3p;hsa-miR-3065-3p;hsa-miR-33a-3p | 10 | CCND2 | Sponge network | -2.663 | 0.00676 | -2.811 | 0.0014 | 0.263 |
| 133 | AC004540.5 |
hsa-let-7f-1-3p;hsa-miR-142-3p;hsa-miR-205-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-629-3p | 10 | LIFR | Sponge network | -2.462 | 0.01794 | -4.51 | 1.0E-5 | 0.262 |
| 134 | TRHDE-AS1 |
hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-224-5p;hsa-miR-33a-3p;hsa-miR-34a-5p;hsa-miR-590-3p;hsa-miR-92a-3p;hsa-miR-93-3p;hsa-miR-93-5p | 15 | SPRED1 | Sponge network | -6.205 | 0.01165 | -1.208 | 0.0043 | 0.26 |
| 135 | AC016747.3 | hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-15b-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-20b-5p;hsa-miR-324-3p;hsa-miR-429;hsa-miR-93-5p | 11 | CCND2 | Sponge network | -0.828 | 0.36258 | -2.811 | 0.0014 | 0.258 |
| 136 | BAIAP2-AS1 | hsa-miR-142-3p;hsa-miR-19b-3p;hsa-miR-205-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-590-3p;hsa-miR-629-3p | 12 | LIFR | Sponge network | -1.355 | 0.0161 | -4.51 | 1.0E-5 | 0.258 |
| 137 | SOCS2-AS1 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-200a-3p;hsa-miR-20b-5p;hsa-miR-28-5p;hsa-miR-324-3p;hsa-miR-33a-3p;hsa-miR-3607-3p;hsa-miR-93-5p | 16 | CCND2 | Sponge network | -4.167 | 1.0E-5 | -2.811 | 0.0014 | 0.258 |
| 138 | RP11-887P2.5 |
hsa-let-7d-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-130b-3p;hsa-miR-148b-5p;hsa-miR-16-1-3p;hsa-miR-19b-1-5p;hsa-miR-22-5p;hsa-miR-301a-3p;hsa-miR-33a-3p;hsa-miR-3614-5p;hsa-miR-421;hsa-miR-944 | 13 | PRLR | Sponge network | -9.865 | 1.0E-5 | -5.28 | 0.00088 | 0.258 |
| 139 | RP11-597D13.9 |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-200a-3p;hsa-miR-20b-5p;hsa-miR-30d-3p;hsa-miR-324-3p;hsa-miR-33a-3p;hsa-miR-429;hsa-miR-93-5p;hsa-miR-96-5p | 19 | CCND2 | Sponge network | -2.494 | 0.07597 | -2.811 | 0.0014 | 0.252 |
| 140 | AF131215.9 | hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-10a-3p;hsa-miR-130b-5p;hsa-miR-151a-3p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-200a-3p;hsa-miR-501-5p | 10 | CCND2 | Sponge network | -0.619 | 0.51233 | -2.811 | 0.0014 | 0.251 |
| 141 | AC003090.1 |
hsa-miR-106b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-224-5p;hsa-miR-590-3p;hsa-miR-93-5p | 11 | SPRED1 | Sponge network | -7.817 | 0.00161 | -1.208 | 0.0043 | 0.251 |
| 142 | DNM3OS |
hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-151a-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-191-5p;hsa-miR-200a-3p;hsa-miR-20b-5p;hsa-miR-224-3p;hsa-miR-3065-3p;hsa-miR-3065-5p;hsa-miR-30d-3p;hsa-miR-33a-3p;hsa-miR-378a-3p;hsa-miR-429;hsa-miR-501-5p;hsa-miR-550a-5p;hsa-miR-93-5p;hsa-miR-96-5p | 25 | CCND2 | Sponge network | -3.933 | 0.00059 | -2.811 | 0.0014 | 0.25 |
| 143 | SH3RF3-AS1 | hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-224-3p;hsa-miR-28-5p;hsa-miR-3065-3p;hsa-miR-378a-3p | 10 | CCND2 | Sponge network | -2.461 | 0.06722 | -2.811 | 0.0014 | 0.25 |