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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-107 ABCC3 -0.18 0.01038 2.55 0 miRanda; miRNATAP -0.83 0 NA
2 hsa-miR-107 ABCC5 -0.18 0.01038 -0.18 0.03187 miRanda -0.14 0.00522 NA
3 hsa-miR-107 ABR -0.18 0.01038 1.52 0 miRanda -0.34 0 NA
4 hsa-miR-107 ACAP3 -0.18 0.01038 0.41 0 miRNATAP -0.11 0.00858 NA
5 hsa-miR-107 ACTG1 -0.18 0.01038 0.35 0 miRanda; miRNATAP -0.12 9.0E-5 NA
6 hsa-miR-107 ACVR1 -0.18 0.01038 0.68 0 miRanda -0.22 4.0E-5 NA
7 hsa-miR-107 ADAM15 -0.18 0.01038 0.82 0 miRanda -0.17 0.0001 NA
8 hsa-miR-107 ADAMTS14 -0.18 0.01038 3.41 0 miRanda -1.46 0 NA
9 hsa-miR-107 ADAMTS6 -0.18 0.01038 0.39 0.01384 miRanda -0.2 0.03503 NA
10 hsa-miR-107 ADAMTSL1 -0.18 0.01038 -0.23 0.20826 miRanda -0.38 0.00048 NA
11 hsa-miR-107 ADAP2 -0.18 0.01038 0.95 0 miRanda -0.2 0.00199 NA
12 hsa-miR-107 ADAR -0.18 0.01038 0.17 0.00125 miRanda -0.13 5.0E-5 NA
13 hsa-miR-107 ADARB1 -0.18 0.01038 0.52 0 miRanda -0.1 0.03551 NA
14 hsa-miR-107 ADCYAP1 -0.18 0.01038 -0.38 0.19309 MirTarget; PITA; miRanda; miRNATAP -0.35 0.04932 NA
15 hsa-miR-107 ADD2 -0.18 0.01038 -0.53 0.01427 miRNAWalker2 validate; miRNATAP -0.31 0.01557 NA
16 hsa-miR-107 ADK -0.18 0.01038 1.02 0 miRanda -0.1 0.03034 NA
17 hsa-miR-107 ADRB2 -0.18 0.01038 -0.77 0 miRanda -0.2 0.03212 NA
18 hsa-miR-107 AFF2 -0.18 0.01038 1.69 0 mirMAP; miRNATAP -0.7 0 NA
19 hsa-miR-107 AHNAK -0.18 0.01038 -0.27 0.01079 miRanda -0.2 0.00108 NA
20 hsa-miR-107 AHSA2 -0.18 0.01038 0.04 0.73127 miRanda -0.17 0.02916 NA
21 hsa-miR-107 AIM1L -0.18 0.01038 2.36 0 miRanda -0.71 0 NA
22 hsa-miR-107 AKIRIN2 -0.18 0.01038 0.4 0 miRanda -0.13 7.0E-5 NA
23 hsa-miR-107 AKT3 -0.18 0.01038 -0.02 0.82269 PITA; miRanda -0.17 0.00039 NA
24 hsa-miR-107 ALDH3B2 -0.18 0.01038 3.1 0 miRanda -0.87 0 NA
25 hsa-miR-107 AMOT -0.18 0.01038 0.84 0 MirTarget; PITA; miRanda; miRNATAP -0.5 0 NA
26 hsa-miR-107 AMPH -0.18 0.01038 -0.69 0.00031 miRanda -0.26 0.02181 NA
27 hsa-miR-107 AMT -0.18 0.01038 -0.2 0.1701 miRanda -0.18 0.0364 NA
28 hsa-miR-107 ANK1 -0.18 0.01038 -0.67 0.00014 PITA; miRanda; miRNATAP -0.4 0.00014 NA
29 hsa-miR-107 ANKRD30B -0.18 0.01038 2.11 0 miRanda -0.91 0 NA
30 hsa-miR-107 ANKRD36 -0.18 0.01038 -0.15 0.13119 miRanda -0.12 0.04535 NA
31 hsa-miR-107 ANKRD44 -0.18 0.01038 -0.68 0.00013 miRanda -0.26 0.01285 NA
32 hsa-miR-107 ANXA1 -0.18 0.01038 1.54 0 miRanda -0.59 0 NA
33 hsa-miR-107 ANXA4 -0.18 0.01038 0.11 0.07028 miRanda -0.1 0.00669 NA
34 hsa-miR-107 AP2A1 -0.18 0.01038 0.52 0 miRanda -0.17 0 NA
35 hsa-miR-107 APOBEC3C -0.18 0.01038 0.02 0.83693 miRanda -0.3 0 NA
36 hsa-miR-107 APOBEC3D -0.18 0.01038 -0.4 0.00993 miRanda -0.52 0 NA
37 hsa-miR-107 AREG -0.18 0.01038 1.21 9.0E-5 miRanda -0.49 0.00903 NA
38 hsa-miR-107 ARF6 -0.18 0.01038 0.28 0 MirTarget; miRanda -0.13 0.00032 NA
39 hsa-miR-107 ARHGAP1 -0.18 0.01038 0.44 0 miRanda -0.21 0 NA
40 hsa-miR-107 ARHGAP18 -0.18 0.01038 0.72 0 miRanda -0.14 0.01364 NA
41 hsa-miR-107 ARHGAP19 -0.18 0.01038 0.99 0 MirTarget; miRanda; mirMAP -0.2 0.02303 NA
42 hsa-miR-107 ARL11 -0.18 0.01038 0.39 0.0309 miRanda -0.4 0.00018 NA
43 hsa-miR-107 ARL4C -0.18 0.01038 -0.49 0.00682 MirTarget; miRanda -0.6 0 NA
44 hsa-miR-107 ARL6IP6 -0.18 0.01038 0.29 3.0E-5 miRanda -0.12 0.00447 NA
45 hsa-miR-107 ARMCX3 -0.18 0.01038 1.37 0 miRanda -0.3 0.00259 NA
46 hsa-miR-107 ARPC5L -0.18 0.01038 0.57 0 miRanda -0.14 0.00024 NA
47 hsa-miR-107 ASCC3 -0.18 0.01038 0.73 0 miRNATAP -0.14 0.00438 NA
48 hsa-miR-107 ATG7 -0.18 0.01038 0.28 0 miRanda -0.18 0 NA
49 hsa-miR-107 ATP2B4 -0.18 0.01038 0.14 0.07737 miRanda -0.15 0.00233 NA
50 hsa-miR-107 ATP8B4 -0.18 0.01038 -0.65 0 miRanda -0.33 3.0E-5 NA
51 hsa-miR-107 B3GALT4 -0.18 0.01038 0.45 0 miRanda -0.21 2.0E-5 NA
52 hsa-miR-107 BACH1 -0.18 0.01038 0.08 0.33202 miRanda -0.14 0.0046 NA
53 hsa-miR-107 BACH2 -0.18 0.01038 -0.16 0.3043 MirTarget; PITA; miRNATAP -0.56 0 NA
54 hsa-miR-107 BASP1 -0.18 0.01038 1.14 0 miRanda -0.64 0 NA
55 hsa-miR-107 BBOX1 -0.18 0.01038 -1.6 0 miRanda -0.35 0.02912 NA
56 hsa-miR-107 BDNF -0.18 0.01038 0.14 0.49191 MirTarget; PITA; miRanda; miRNATAP -0.3 0.01489 27498977 MicroRNA 107 inhibits tumor growth and metastasis by targeting the BDNF mediated PI3K/AKT pathway in human non small lung cancer; In addition BDNF expression was upregulated and inversely correlated with miR-107 in NSCLC tissues; Enforced overexpression of BDNF effectively reversed the tumor suppressive functions of miR-107 on NSCLC proliferation migration and invasion; miR-107 overexpression or downregulation of BDNF was able to inhibit activation of PI3K/AKT signaling pathway; Taken together our findings present the first evidence that miR-107 could suppress NSCLC metastasis by targeting BDNF and indirectly regulating PI3K/AKT signaling pathway which might lead to a potential therapeutic strategy focusing on miR-107 and BDNF for human NSCLC
57 hsa-miR-107 BEST1 -0.18 0.01038 0.48 0 miRanda -0.2 0.00012 NA
58 hsa-miR-107 BHLHE40 -0.18 0.01038 1.57 0 MirTarget; miRanda -0.35 0.00043 NA
59 hsa-miR-107 BHLHE41 -0.18 0.01038 1.06 0 miRanda -0.41 0 NA
60 hsa-miR-107 BICD1 -0.18 0.01038 0.63 0 miRanda -0.13 0.04894 NA
61 hsa-miR-107 BTLA -0.18 0.01038 -1.08 0.00012 MirTarget; PITA; miRanda; miRNATAP -0.91 0 NA
62 hsa-miR-107 BTN2A2 -0.18 0.01038 0.18 0.01967 miRanda -0.27 0 NA
63 hsa-miR-107 C12orf76 -0.18 0.01038 0.64 0 miRNATAP -0.14 0.00053 NA
64 hsa-miR-107 C1QB -0.18 0.01038 0.83 2.0E-5 miRanda -0.69 0 NA
65 hsa-miR-107 C1orf226 -0.18 0.01038 1.67 0 miRNATAP -0.34 0.00045 NA
66 hsa-miR-107 C9orf69 -0.18 0.01038 0.44 0 PITA; miRNATAP -0.12 0.00015 NA
67 hsa-miR-107 CACNA1C -0.18 0.01038 0.89 0 miRNATAP -0.19 0.02577 NA
68 hsa-miR-107 CACNA1E -0.18 0.01038 -0.7 0.02014 miRanda; miRNATAP -0.43 0.01693 NA
69 hsa-miR-107 CADM3 -0.18 0.01038 -0.92 0.02502 miRanda -1.79 0 NA
70 hsa-miR-107 CALCA -0.18 0.01038 -1.77 0.00025 miRanda -0.57 0.04942 NA
71 hsa-miR-107 CALCOCO1 -0.18 0.01038 0.37 0 miRanda -0.11 0.00112 NA
72 hsa-miR-107 CALD1 -0.18 0.01038 -0.07 0.34856 miRanda -0.13 0.0035 NA
73 hsa-miR-107 CAPN12 -0.18 0.01038 1.01 0 miRanda -0.43 0 NA
74 hsa-miR-107 CAPN2 -0.18 0.01038 0.31 0 miRanda -0.17 1.0E-5 NA
75 hsa-miR-107 CARM1 -0.18 0.01038 0.34 0 MirTarget; PITA; miRanda; miRNATAP -0.14 0 NA
76 hsa-miR-107 CASP8 -0.18 0.01038 0.23 0.00107 miRanda -0.14 0.00115 NA
77 hsa-miR-107 CC2D1B -0.18 0.01038 0.31 0 MirTarget; miRanda; miRNATAP -0.15 0 NA
78 hsa-miR-107 CCDC22 -0.18 0.01038 0.32 0 miRanda -0.12 2.0E-5 NA
79 hsa-miR-107 CCL13 -0.18 0.01038 2.13 0 miRanda -1.51 0 NA
80 hsa-miR-107 CCM2 -0.18 0.01038 1.07 0 miRanda -0.34 0 NA
81 hsa-miR-107 CCNA1 -0.18 0.01038 2.22 0 miRanda -1.18 0 NA
82 hsa-miR-107 CCT4 -0.18 0.01038 0.14 0.00445 miRanda -0.1 0.00041 NA
83 hsa-miR-107 CD151 -0.18 0.01038 1.18 0 miRanda -0.27 1.0E-5 NA
84 hsa-miR-107 CD163 -0.18 0.01038 0.36 0.0687 miRanda -0.53 1.0E-5 NA
85 hsa-miR-107 CD164L2 -0.18 0.01038 3.43 0 PITA; miRanda; miRNATAP -1.11 0 NA
86 hsa-miR-107 CD1E -0.18 0.01038 0.39 0.2976 miRanda -1.29 0 NA
87 hsa-miR-107 CD207 -0.18 0.01038 2.6 0 miRanda; miRNATAP -1.55 0 NA
88 hsa-miR-107 CD274 -0.18 0.01038 -0.1 0.62695 miRanda -0.48 7.0E-5 NA
89 hsa-miR-107 CD28 -0.18 0.01038 -0.45 0.08438 miRanda -0.77 0 NA
90 hsa-miR-107 CD37 -0.18 0.01038 -0.03 0.8973 miRanda -0.82 0 NA
91 hsa-miR-107 CD40 -0.18 0.01038 0.47 0.00123 miRanda -0.62 0 NA
92 hsa-miR-107 CD47 -0.18 0.01038 0.38 1.0E-5 miRanda -0.23 1.0E-5 NA
93 hsa-miR-107 CD48 -0.18 0.01038 -0.72 0.00151 miRanda -0.67 0 NA
94 hsa-miR-107 CD69 -0.18 0.01038 -1.03 3.0E-5 miRanda -0.59 9.0E-5 NA
95 hsa-miR-107 CD7 -0.18 0.01038 -0.43 0.08812 miRanda -0.98 0 NA
96 hsa-miR-107 CD72 -0.18 0.01038 -0.52 0.00055 miRanda -0.38 3.0E-5 NA
97 hsa-miR-107 CD79A -0.18 0.01038 -0.87 0.06804 miRanda -1.73 0 NA
98 hsa-miR-107 CD80 -0.18 0.01038 -0.77 0.00075 MirTarget; miRanda -0.74 0 NA
99 hsa-miR-107 CD84 -0.18 0.01038 -0.23 0.32336 miRanda -0.65 0 NA
100 hsa-miR-107 CD8B -0.18 0.01038 -0.78 0.00538 miRanda -0.63 0.00016 NA
101 hsa-miR-107 CDCA4 -0.18 0.01038 0.61 0 miRNAWalker2 validate; miRanda -0.17 6.0E-5 NA
102 hsa-miR-107 CDHR1 -0.18 0.01038 -1.24 0 miRanda -0.55 0.00055 NA
103 hsa-miR-107 CDK5R1 -0.18 0.01038 0.04 0.73429 PITA; miRanda; miRNATAP -0.26 0.00091 NA
104 hsa-miR-107 CDKAL1 -0.18 0.01038 0.24 0 miRanda -0.12 0.00011 NA
105 hsa-miR-107 CDKN2B -0.18 0.01038 2.7 0 PITA -0.64 0 NA
106 hsa-miR-451a CDKN2B -2.65 0 2.7 0 MirTarget -0.3 0 NA
107 hsa-miR-107 CDR2L -0.18 0.01038 1.01 0 miRanda -0.16 0.0082 NA
108 hsa-miR-107 CECR6 -0.18 0.01038 1.2 0 MirTarget; PITA; miRanda; miRNATAP -0.3 0.00027 NA
109 hsa-miR-107 CELF2 -0.18 0.01038 -0.39 0.0037 miRanda; miRNATAP -0.37 1.0E-5 NA
110 hsa-miR-107 CELSR2 -0.18 0.01038 0.06 0.50716 MirTarget; PITA; miRanda; miRNATAP -0.21 2.0E-5 NA
111 hsa-miR-107 CERKL -0.18 0.01038 0.19 0.2927 miRanda -0.6 0 NA
112 hsa-miR-107 CFL1 -0.18 0.01038 0.44 0 MirTarget; miRanda; miRNATAP -0.16 1.0E-5 NA
113 hsa-miR-107 CFLAR -0.18 0.01038 -0.27 0.00448 miRanda -0.25 1.0E-5 NA
114 hsa-miR-107 CFTR -0.18 0.01038 0.63 0.06755 miRanda -1.42 0 NA
115 hsa-miR-107 CHST11 -0.18 0.01038 1.09 0 MirTarget; PITA; miRanda; miRNATAP -0.19 0.01134 NA
116 hsa-miR-107 CLEC4F -0.18 0.01038 0.57 0.02736 miRanda -0.79 0 NA
117 hsa-miR-107 CLEC5A -0.18 0.01038 0.95 6.0E-5 miRanda -0.65 0 NA
118 hsa-miR-107 CLU -0.18 0.01038 0.99 0 miRanda -0.89 0 NA
119 hsa-miR-107 CMTM8 -0.18 0.01038 0.7 0 miRanda -0.15 0.00288 NA
120 hsa-miR-107 CNIH3 -0.18 0.01038 0.68 0 miRanda; miRNATAP -0.46 0 NA
121 hsa-miR-107 CNN3 -0.18 0.01038 0.42 0 miRanda -0.25 0 NA
122 hsa-miR-107 CNTNAP1 -0.18 0.01038 0.75 0 MirTarget; PITA; miRanda; miRNATAP -0.26 0.00087 NA
123 hsa-miR-107 COL1A1 -0.18 0.01038 1.66 0 PITA; miRanda -1.12 0 NA
124 hsa-miR-107 COL24A1 -0.18 0.01038 -0.04 0.86486 miRanda -0.77 0 NA
125 hsa-miR-107 COL3A1 -0.18 0.01038 0.85 0.00021 miRanda -0.69 0 NA
126 hsa-miR-107 COL5A1 -0.18 0.01038 1.09 0 miRanda -0.69 0 NA
127 hsa-miR-107 COLQ -0.18 0.01038 0.12 0.3089 miRanda -0.15 0.03017 NA
128 hsa-miR-107 CORIN -0.18 0.01038 0.18 0.30693 miRanda -0.43 7.0E-5 NA
129 hsa-miR-107 CPT1B -0.18 0.01038 0.66 0 miRNATAP -0.34 3.0E-5 NA
130 hsa-miR-107 CREB5 -0.18 0.01038 1.06 0 miRNATAP -0.78 0 NA
131 hsa-miR-107 CSF1 -0.18 0.01038 0.08 0.57179 miRanda -0.43 0 NA
132 hsa-miR-107 CSF1R -0.18 0.01038 0.71 0 miRanda -0.52 0 NA
133 hsa-miR-107 CSNK1G2 -0.18 0.01038 0.23 0 miRNAWalker2 validate; MirTarget; PITA; miRanda; miRNATAP -0.16 0 NA
134 hsa-miR-107 CST3 -0.18 0.01038 0.29 0.00043 miRanda -0.14 0.0052 NA
135 hsa-miR-107 CTDSPL -0.18 0.01038 -0.15 0.04678 mirMAP -0.14 0.00166 NA
136 hsa-miR-107 CTSD -0.18 0.01038 0.82 0 miRanda -0.31 0 NA
137 hsa-miR-107 CXCL3 -0.18 0.01038 -0.46 0.1042 miRanda -0.46 0.00713 NA
138 hsa-miR-107 CXCR3 -0.18 0.01038 -0.45 0.02937 miRanda -0.66 0 NA
139 hsa-miR-107 CXCR6 -0.18 0.01038 -0.96 7.0E-5 miRanda -0.82 0 NA
140 hsa-miR-107 CYB5R4 -0.18 0.01038 -0.14 0.05893 miRanda -0.11 0.01075 NA
141 hsa-miR-107 CYP2S1 -0.18 0.01038 3.11 0 miRanda -1.48 0 NA
142 hsa-miR-107 CYSLTR2 -0.18 0.01038 2.6 0 miRanda -1.07 0 NA
143 hsa-miR-107 CYTH4 -0.18 0.01038 0.22 0.22039 miRanda -0.61 0 NA
144 hsa-miR-107 DAPK1 -0.18 0.01038 -0.84 0 miRNAWalker2 validate; miRTarBase -0.2 0.02031 NA
145 hsa-miR-107 DAPP1 -0.18 0.01038 0.13 0.64456 miRanda -0.95 0 NA
146 hsa-miR-107 DBNDD2 -0.18 0.01038 0.69 0 miRanda -0.2 1.0E-5 NA
147 hsa-miR-107 DBNL -0.18 0.01038 0.11 0.01357 mirMAP -0.11 3.0E-5 NA
148 hsa-miR-107 DCBLD2 -0.18 0.01038 0.85 0 MirTarget; PITA; miRanda; miRNATAP -0.15 0.00937 NA
149 hsa-miR-107 DCLK1 -0.18 0.01038 -0.82 0.00021 miRNATAP -0.56 3.0E-5 NA
150 hsa-miR-107 DCUN1D3 -0.18 0.01038 0.64 0 MirTarget; PITA; miRanda -0.17 0.00172 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 IMMUNE SYSTEM PROCESS 130 1984 1.715e-19 7.979e-16
2 IMMUNE RESPONSE 83 1100 7.983e-16 1.238e-12
3 BIOLOGICAL ADHESION 80 1032 6.333e-16 1.238e-12
4 SINGLE ORGANISM CELL ADHESION 47 459 5.655e-14 6.578e-11
5 CELL ACTIVATION 52 568 2.182e-13 2.031e-10
6 CELL CELL ADHESION 53 608 8.799e-13 6.824e-10
7 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 72 1021 2.218e-12 1.474e-09
8 LEUKOCYTE CELL CELL ADHESION 32 255 3.152e-12 1.833e-09
9 REGULATION OF CELLULAR COMPONENT MOVEMENT 59 771 1.002e-11 5.178e-09
10 LYMPHOCYTE ACTIVATION 36 342 2.497e-11 1.162e-08
11 IMMUNE SYSTEM DEVELOPMENT 48 582 7.677e-11 3.247e-08
12 LEUKOCYTE ACTIVATION 39 414 1.061e-10 4.115e-08
13 POSITIVE REGULATION OF RESPONSE TO STIMULUS 104 1929 2.834e-10 1.015e-07
14 REGULATION OF IMMUNE SYSTEM PROCESS 82 1403 7.644e-10 2.541e-07
15 REGULATION OF CYTOKINE PRODUCTION 45 563 8.397e-10 2.605e-07
16 ADAPTIVE IMMUNE RESPONSE 30 288 1.507e-09 4.384e-07
17 LEUKOCYTE DIFFERENTIATION 30 292 2.092e-09 5.589e-07
18 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 79 1360 2.162e-09 5.589e-07
19 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 58 867 2.661e-09 6.517e-07
20 ALPHA BETA T CELL ACTIVATION 13 54 3.275e-09 7.271e-07
21 IMMUNE EFFECTOR PROCESS 40 486 3.281e-09 7.271e-07
22 DEFENSE RESPONSE 73 1231 4.006e-09 8.473e-07
23 ORGAN MORPHOGENESIS 56 841 6.016e-09 1.217e-06
24 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 79 1395 6.736e-09 1.291e-06
25 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 62 983 6.935e-09 1.291e-06
26 POSITIVE REGULATION OF MOLECULAR FUNCTION 94 1791 9.337e-09 1.671e-06
27 LOCOMOTION 67 1114 1.08e-08 1.861e-06
28 POSITIVE REGULATION OF CATALYTIC ACTIVITY 83 1518 1.313e-08 2.182e-06
29 REGULATION OF CELL PROLIFERATION 82 1496 1.458e-08 2.34e-06
30 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 53 801 1.947e-08 3.02e-06
31 CELL PROLIFERATION 47 672 2.444e-08 3.668e-06
32 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 88 1672 2.663e-08 3.872e-06
33 REGULATION OF CELL ACTIVATION 38 484 2.9e-08 4.077e-06
34 INTRACELLULAR SIGNAL TRANSDUCTION 84 1572 2.979e-08 4.077e-06
35 LEUKOCYTE PROLIFERATION 15 88 3.17e-08 4.215e-06
36 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 72 1275 3.837e-08 4.919e-06
37 VASCULATURE DEVELOPMENT 37 469 3.911e-08 4.919e-06
38 ALPHA BETA T CELL DIFFERENTIATION 11 45 4.524e-08 5.54e-06
39 RESPONSE TO WOUNDING 41 563 6.635e-08 7.916e-06
40 CELL MOTILITY 53 835 7.592e-08 8.616e-06
41 LOCALIZATION OF CELL 53 835 7.592e-08 8.616e-06
42 POSITIVE REGULATION OF CELL COMMUNICATION 81 1532 8.584e-08 9.509e-06
43 T CELL DIFFERENTIATION 17 123 9.679e-08 1.047e-05
44 POSITIVE REGULATION OF CYTOKINE PRODUCTION 31 370 1.338e-07 1.415e-05
45 REGULATION OF IMMUNE RESPONSE 53 858 1.806e-07 1.867e-05
46 LYMPHOCYTE DIFFERENTIATION 22 209 1.942e-07 1.964e-05
47 POSITIVE REGULATION OF LOCOMOTION 33 420 2.357e-07 2.334e-05
48 RESPONSE TO VIRUS 24 247 2.45e-07 2.375e-05
49 EMBRYO DEVELOPMENT 54 894 2.804e-07 2.662e-05
50 INNATE IMMUNE RESPONSE 42 619 3.161e-07 2.942e-05
51 TISSUE MORPHOGENESIS 38 533 3.461e-07 3.158e-05
52 WOUND HEALING 35 470 3.667e-07 3.22e-05
53 REGULATION OF PROTEIN LOCALIZATION 56 950 3.668e-07 3.22e-05
54 REGULATION OF TRANSPORT 89 1804 3.998e-07 3.445e-05
55 POSITIVE REGULATION OF HYDROLASE ACTIVITY 54 905 4.116e-07 3.482e-05
56 CARDIOVASCULAR SYSTEM DEVELOPMENT 49 788 4.429e-07 3.615e-05
57 CIRCULATORY SYSTEM DEVELOPMENT 49 788 4.429e-07 3.615e-05
58 REGULATION OF CELL ADHESION 42 629 4.839e-07 3.818e-05
59 TISSUE DEVELOPMENT 78 1518 4.842e-07 3.818e-05
60 REGULATION OF LEUKOCYTE PROLIFERATION 21 206 6.268e-07 4.861e-05
61 CELL DEVELOPMENT 74 1426 6.819e-07 5.202e-05
62 EXTRACELLULAR STRUCTURE ORGANIZATION 26 304 9.338e-07 7.008e-05
63 BLOOD VESSEL MORPHOGENESIS 29 364 9.6e-07 7.09e-05
64 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 29 372 1.49e-06 0.0001083
65 EPITHELIUM DEVELOPMENT 54 945 1.55e-06 0.0001109
66 GLAND DEVELOPMENT 30 395 1.685e-06 0.0001188
67 REGULATION OF CELL DIFFERENTIATION 75 1492 1.878e-06 0.0001304
68 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 81 1656 2.014e-06 0.0001378
69 LEUKOCYTE MIGRATION 23 259 2.088e-06 0.0001408
70 MORPHOGENESIS OF AN EPITHELIUM 30 400 2.178e-06 0.0001447
71 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 54 957 2.26e-06 0.000146
72 NEGATIVE REGULATION OF IMMUNE RESPONSE 15 121 2.24e-06 0.000146
73 NEGATIVE REGULATION OF CELL COMMUNICATION 63 1192 2.76e-06 0.0001759
74 TUBE MORPHOGENESIS 26 323 2.89e-06 0.0001817
75 RESPONSE TO EXTERNAL STIMULUS 86 1821 3.806e-06 0.0002361
76 INTEGRIN MEDIATED SIGNALING PATHWAY 12 82 4.042e-06 0.0002475
77 POSITIVE REGULATION OF CELL ACTIVATION 25 311 4.584e-06 0.000277
78 RESPONSE TO CYTOKINE 43 714 5.178e-06 0.0003089
79 POSITIVE REGULATION OF CELL ADHESION 28 376 5.425e-06 0.0003196
80 DEFENSE RESPONSE TO VIRUS 17 164 5.809e-06 0.0003296
81 POSITIVE REGULATION OF CELL PROLIFERATION 47 814 5.781e-06 0.0003296
82 RESPONSE TO LIPID 50 888 5.786e-06 0.0003296
83 CARDIAC SEPTUM DEVELOPMENT 12 85 5.933e-06 0.0003326
84 REGULATION OF HYDROLASE ACTIVITY 67 1327 6.089e-06 0.0003373
85 REGULATION OF CELLULAR LOCALIZATION 65 1277 6.538e-06 0.0003538
86 REGULATION OF GTPASE ACTIVITY 41 673 6.538e-06 0.0003538
87 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 86 1848 6.752e-06 0.0003611
88 REGULATION OF CYTOKINE SECRETION 16 149 6.919e-06 0.0003659
89 REGULATION OF KINASE ACTIVITY 45 776 8.232e-06 0.0004213
90 EMBRYONIC MORPHOGENESIS 35 539 8.116e-06 0.0004213
91 NEGATIVE REGULATION OF CELL DIFFERENTIATION 38 609 8.33e-06 0.0004213
92 REGULATION OF ORGAN MORPHOGENESIS 21 242 8.242e-06 0.0004213
93 POSITIVE REGULATION OF IMMUNE RESPONSE 36 563 8.464e-06 0.0004235
94 NEGATIVE REGULATION OF LOCOMOTION 22 263 9.078e-06 0.0004494
95 POSITIVE REGULATION OF LEUKOCYTE PROLIFERATION 15 136 9.629e-06 0.0004716
96 ADAPTIVE IMMUNE RESPONSE BASED ON SOMATIC RECOMBINATION OF IMMUNE RECEPTORS BUILT FROM IMMUNOGLOBULIN SUPERFAMILY DOMAINS 16 154 1.056e-05 0.0005016
97 SKELETAL SYSTEM DEVELOPMENT 31 455 1.046e-05 0.0005016
98 AMEBOIDAL TYPE CELL MIGRATION 16 154 1.056e-05 0.0005016
99 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 72 1492 1.263e-05 0.0005936
100 T CELL DIFFERENTIATION INVOLVED IN IMMUNE RESPONSE 7 29 1.473e-05 0.0006855
101 REGULATION OF VASCULATURE DEVELOPMENT 20 233 1.58e-05 0.0007278
102 REGULATION OF SECRETION 41 699 1.604e-05 0.0007318
103 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 48 876 1.815e-05 0.0008121
104 REGULATION OF PHOSPHORUS METABOLIC PROCESS 76 1618 1.811e-05 0.0008121
105 REGULATION OF CELL CELL ADHESION 27 380 1.853e-05 0.0008209
106 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 23 296 1.893e-05 0.000831
107 NEUROGENESIS 68 1402 1.917e-05 0.0008335
108 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 58 1142 2.265e-05 0.0009759
109 GLAND MORPHOGENESIS 12 97 2.346e-05 0.001001
110 REGULATION OF PROTEIN SECRETION 27 389 2.796e-05 0.001174
111 NEGATIVE REGULATION OF OSSIFICATION 10 69 2.8e-05 0.001174
112 POSITIVE REGULATION OF CELL CELL ADHESION 20 243 2.902e-05 0.001206
113 TUBE DEVELOPMENT 34 552 3.235e-05 0.00132
114 REGULATION OF CELL MORPHOGENESIS 34 552 3.235e-05 0.00132
115 REGULATION OF HOMOTYPIC CELL CELL ADHESION 23 307 3.367e-05 0.001362
116 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 34 554 3.478e-05 0.001395
117 MYELOID CELL DIFFERENTIATION 17 189 3.741e-05 0.001488
118 REGULATION OF PROTEIN MODIFICATION PROCESS 78 1710 3.815e-05 0.001504
119 STEM CELL DIFFERENTIATION 17 190 4.001e-05 0.001564
120 CELLULAR RESPONSE TO CYTOKINE STIMULUS 36 606 4.064e-05 0.001576
121 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 53 1036 4.285e-05 0.001621
122 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 53 1036 4.285e-05 0.001621
123 DEVELOPMENTAL GROWTH 24 333 4.262e-05 0.001621
124 REGULATION OF ACTIN FILAMENT BASED PROCESS 23 312 4.328e-05 0.001624
125 CD4 POSITIVE ALPHA BETA T CELL ACTIVATION 7 34 4.479e-05 0.001638
126 HEART VALVE DEVELOPMENT 7 34 4.479e-05 0.001638
127 NEGATIVE REGULATION OF CYTOKINE PRODUCTION 18 211 4.507e-05 0.001638
128 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 32 514 4.486e-05 0.001638
129 NEGATIVE REGULATION OF CYTOKINE SECRETION 8 46 4.647e-05 0.001676
130 INTERFERON GAMMA PRODUCTION 5 15 4.717e-05 0.001688
131 ANGIOGENESIS 22 293 4.801e-05 0.001705
132 REGULATION OF CELL DEATH 69 1472 4.874e-05 0.001718
133 POSITIVE REGULATION OF IMMUNE EFFECTOR PROCESS 15 156 4.933e-05 0.001726
134 T CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE 9 60 5.32e-05 0.001847
135 REGULATION OF VIRAL GENOME REPLICATION 10 75 5.843e-05 0.001999
136 EMBRYONIC ORGAN DEVELOPMENT 27 406 5.837e-05 0.001999
137 CELL CELL SIGNALING 42 767 6.198e-05 0.002105
138 REGULATION OF OSSIFICATION 16 178 6.337e-05 0.002137
139 T CELL SELECTION 7 36 6.61e-05 0.002213
140 REGULATION OF MEMBRANE POTENTIAL 24 343 6.795e-05 0.002243
141 NEGATIVE REGULATION OF CELL DEATH 46 872 6.798e-05 0.002243
142 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 56 1135 6.93e-05 0.002271
143 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 51 1004 7.176e-05 0.002335
144 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 48 926 7.236e-05 0.002338
145 NEGATIVE REGULATION OF VIRAL GENOME REPLICATION 8 49 7.443e-05 0.002388
146 CELLULAR RESPONSE TO INTERLEUKIN 4 6 26 8.056e-05 0.002567
147 NEGATIVE REGULATION OF TISSUE REMODELING 5 17 9.263e-05 0.002932
148 COLLAGEN FIBRIL ORGANIZATION 7 38 9.504e-05 0.002968
149 TAXIS 29 464 9.461e-05 0.002968
150 NEURAL CREST CELL MIGRATION 8 51 9.989e-05 0.003092
151 REGULATION OF SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM 17 205 0.0001033 0.003092
152 HEART DEVELOPMENT 29 466 0.0001019 0.003092
153 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 31 513 0.0001015 0.003092
154 POSITIVE REGULATION OF CYTOKINE SECRETION 11 96 0.0001037 0.003092
155 REGULATION OF CELL DEVELOPMENT 44 836 0.0001031 0.003092
156 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 38 684 0.000103 0.003092
157 NEUROMUSCULAR PROCESS 11 97 0.0001139 0.003377
158 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 32 541 0.000117 0.003425
159 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 32 541 0.000117 0.003425
160 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 38 689 0.0001196 0.003478
161 REGULATION OF IMMUNE EFFECTOR PROCESS 27 424 0.0001205 0.003482
162 NEGATIVE REGULATION OF MOLECULAR FUNCTION 53 1079 0.000122 0.003504
163 LYMPHOCYTE ACTIVATION INVOLVED IN IMMUNE RESPONSE 11 98 0.000125 0.00356
164 SYNCYTIUM FORMATION 6 28 0.0001255 0.00356
165 RESPONSE TO STEROID HORMONE 30 497 0.0001335 0.003756
166 ACTIN FILAMENT BASED PROCESS 28 450 0.000134 0.003756
167 MESENCHYMAL CELL DIFFERENTIATION 13 134 0.0001414 0.00394
168 POSITIVE REGULATION OF PROTEIN SECRETION 17 211 0.0001467 0.004062
169 NEGATIVE REGULATION OF G PROTEIN COUPLED RECEPTOR PROTEIN SIGNALING PATHWAY 7 41 0.0001571 0.004299
170 AORTA DEVELOPMENT 7 41 0.0001571 0.004299
171 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 34 602 0.0001743 0.004742
172 POSITIVE REGULATION OF KINASE ACTIVITY 29 482 0.0001816 0.004875
173 BONE DEVELOPMENT 14 156 0.0001823 0.004875
174 UROGENITAL SYSTEM DEVELOPMENT 21 299 0.0001808 0.004875
175 CD4 POSITIVE OR CD8 POSITIVE ALPHA BETA T CELL LINEAGE COMMITMENT 4 11 0.0001951 0.005187
176 ENDOCYTOSIS 30 509 0.0002018 0.005335
177 CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE 13 139 0.0002042 0.005368
178 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 11 104 0.000213 0.005568
179 MYOBLAST FUSION 5 20 0.000216 0.005614
180 ENDOTHELIAL CELL DIFFERENTIATION 9 72 0.0002252 0.005823
181 RESPONSE TO INTERLEUKIN 4 6 31 0.0002278 0.005856
182 REGULATION OF TRANSFERASE ACTIVITY 47 946 0.0002297 0.005871
183 REGULATION OF ADAPTIVE IMMUNE RESPONSE 12 123 0.0002398 0.006098
184 NEGATIVE REGULATION OF VIRAL PROCESS 10 89 0.0002497 0.006315
185 PLATELET ACTIVATION 13 142 0.0002523 0.006346
186 BEHAVIOR 30 516 0.0002547 0.006373
187 NEGATIVE REGULATION OF PHOSPHORYLATION 26 422 0.0002684 0.00668
188 SALIVARY GLAND DEVELOPMENT 6 32 0.0002736 0.006715
189 POSITIVE REGULATION OF MAPK CASCADE 28 470 0.0002742 0.006715
190 REGULATION OF MULTI ORGANISM PROCESS 28 470 0.0002742 0.006715
191 T HELPER 1 TYPE IMMUNE RESPONSE 5 21 0.0002768 0.006742
192 NEGATIVE REGULATION OF CELL ADHESION 17 223 0.0002833 0.006865
193 EXOCRINE SYSTEM DEVELOPMENT 7 45 0.0002869 0.006916
194 CARDIAC CHAMBER DEVELOPMENT 13 144 0.0002895 0.006944
195 HEMOSTASIS 21 311 0.0003083 0.007356
196 RESPONSE TO ESTRADIOL 13 146 0.0003313 0.007865
197 REGULATION OF CELLULAR COMPONENT SIZE 22 337 0.0003571 0.008284
198 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 77 1805 0.0003579 0.008284
199 REGULATION OF T CELL PROLIFERATION 13 147 0.000354 0.008284
200 REGULATION OF CYTOSKELETON ORGANIZATION 29 502 0.0003567 0.008284
201 PROTEIN LOCALIZATION 77 1805 0.0003579 0.008284
202 RESPONSE TO BIOTIC STIMULUS 44 886 0.0003663 0.008438
203 NEGATIVE REGULATION OF KINASE ACTIVITY 18 250 0.0003806 0.008681
204 REPRODUCTIVE SYSTEM DEVELOPMENT 25 408 0.0003796 0.008681
205 CELLULAR RESPONSE TO LIPID 27 457 0.000399 0.009057
206 EXTRACELLULAR FIBRIL ORGANIZATION 4 13 0.0004036 0.009115
207 CYTOSKELETON ORGANIZATION 42 838 0.0004122 0.009218
208 LYMPHOCYTE COSTIMULATION 9 78 0.000414 0.009218
209 NEGATIVE REGULATION OF TRANSPORT 27 458 0.0004128 0.009218
210 POSITIVE REGULATION OF T CELL PROLIFERATION 10 95 0.0004252 0.009421
211 REGULATION OF INTERLEUKIN 2 PRODUCTION 7 48 0.0004319 0.009524
212 MESENCHYME DEVELOPMENT 15 190 0.0004394 0.009644
213 REGULATION OF MAPK CASCADE 35 660 0.0004551 0.00993
214 POSITIVE REGULATION OF GENE EXPRESSION 74 1733 0.0004574 0.00993
215 NEGATIVE REGULATION OF MULTI ORGANISM PROCESS 13 151 0.0004588 0.00993
216 MYELOID LEUKOCYTE DIFFERENTIATION 10 96 0.0004626 0.009964
NumGOOverlapSizeP ValueAdj. P Value
1 RECEPTOR BINDING 80 1476 3.648e-08 3.389e-05
2 PROTEIN DOMAIN SPECIFIC BINDING 39 624 6.094e-06 0.00283
3 PROTEIN COMPLEX BINDING 50 935 2.298e-05 0.005338
4 ENZYME BINDING 80 1737 2.14e-05 0.005338
5 MOLECULAR FUNCTION REGULATOR 65 1353 3.963e-05 0.007364
6 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 12 105 5.209e-05 0.008065
NumGOOverlapSizeP ValueAdj. P Value
1 INTRINSIC COMPONENT OF PLASMA MEMBRANE 95 1649 5.889e-11 3.439e-08
2 CELL SURFACE 54 757 1.039e-09 3.033e-07
3 PLASMA MEMBRANE PROTEIN COMPLEX 38 510 1.133e-07 2.206e-05
4 MEMBRANE MICRODOMAIN 25 288 1.151e-06 0.000168
5 NEURON PROJECTION 53 942 3.066e-06 0.0003581
6 ENDOCYTIC VESICLE 22 256 5.901e-06 0.0004308
7 NEURON PART 65 1265 4.813e-06 0.0004308
8 CELL PROJECTION 84 1786 5.879e-06 0.0004308
9 CELL JUNCTION 59 1151 1.463e-05 0.0009492
10 VACUOLE 59 1180 3.012e-05 0.00124
11 RECEPTOR COMPLEX 24 327 3.186e-05 0.00124
12 CELL PROJECTION PART 50 946 3.111e-05 0.00124
13 EXTERNAL SIDE OF PLASMA MEMBRANE 20 238 2.151e-05 0.00124
14 GOLGI APPARATUS 69 1445 2.73e-05 0.00124
15 ENDOSOME 44 793 3.035e-05 0.00124
16 PLASMA MEMBRANE RECEPTOR COMPLEX 16 175 5.164e-05 0.001848
17 INTRACELLULAR VESICLE 61 1259 5.465e-05 0.001848
18 SIDE OF MEMBRANE 28 428 5.697e-05 0.001848
19 AXON 27 418 9.519e-05 0.002926
20 ANCHORING JUNCTION 30 489 0.0001003 0.002928
21 CATION CHANNEL COMPLEX 15 167 0.0001074 0.002987
22 POTASSIUM CHANNEL COMPLEX 10 90 0.0002738 0.00665
23 VACUOLAR PART 37 694 0.0002847 0.00665
24 CELL BODY 29 494 0.000274 0.00665
25 MAIN AXON 8 58 0.0002518 0.00665
26 ENDOSOMAL PART 26 430 0.0003581 0.008043
27 MEMBRANE REGION 53 1134 0.0004089 0.008844
28 EARLY ENDOSOME MEMBRANE 11 113 0.0004396 0.00917
29 TRANSPORTER COMPLEX 21 321 0.0004689 0.009443
30 ENDOCYTIC VESICLE MEMBRANE 13 152 0.0004888 0.009515
31 EARLY ENDOSOME 20 301 0.0005217 0.009828

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Cell_adhesion_molecules_.CAMs._hsa04514 14 145 8.349e-05 0.004137
2 Hippo_signaling_pathway_hsa04390 14 154 0.0001591 0.004137
3 TNF_signaling_pathway_hsa04668 10 108 0.001167 0.02022
4 Cytokine_cytokine_receptor_interaction_hsa04060 17 270 0.002357 0.03064
5 cAMP_signaling_pathway_hsa04024 13 198 0.0052 0.05408
6 Regulation_of_actin_cytoskeleton_hsa04810 13 208 0.007769 0.05608
7 cGMP_PKG_signaling_pathway_hsa04022 11 163 0.007997 0.05608
8 AMPK_signaling_pathway_hsa04152 9 121 0.008628 0.05608
9 MAPK_signaling_pathway_hsa04010 16 295 0.01247 0.06337
10 Phagosome_hsa04145 10 152 0.01318 0.06337
11 Focal_adhesion_hsa04510 12 199 0.0134 0.06337
12 Rap1_signaling_pathway_hsa04015 12 206 0.01717 0.07439
13 Ferroptosis_hsa04216 4 40 0.0279 0.1116
14 Autophagy_animal_hsa04140 8 128 0.03278 0.1218
15 Ras_signaling_pathway_hsa04014 12 232 0.03827 0.1327
16 p53_signaling_pathway_hsa04115 5 68 0.04696 0.1457
17 Apoptosis_hsa04210 8 138 0.04763 0.1457
18 Adherens_junction_hsa04520 5 72 0.0575 0.1661
19 Phospholipase_D_signaling_pathway_hsa04072 8 146 0.06225 0.1704
20 mTOR_signaling_pathway_hsa04150 8 151 0.07267 0.1889
21 Calcium_signaling_pathway_hsa04020 9 182 0.08308 0.2018
22 PI3K_Akt_signaling_pathway_hsa04151 15 352 0.08873 0.2018
23 ECM_receptor_interaction_hsa04512 5 82 0.08925 0.2018
24 TGF_beta_signaling_pathway_hsa04350 5 84 0.0965 0.2052
25 Endocytosis_hsa04144 11 244 0.09865 0.2052
26 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 7 139 0.1094 0.2188
27 Tight_junction_hsa04530 8 170 0.1213 0.2336
28 ABC_transporters_hsa02010 3 45 0.1409 0.2533
29 NF_kappa_B_signaling_pathway_hsa04064 5 95 0.1414 0.2533
30 Lysosome_hsa04142 6 123 0.147 0.2533
31 Cell_cycle_hsa04110 6 124 0.151 0.2533
32 Notch_signaling_pathway_hsa04330 3 48 0.1616 0.2589
33 HIF_1_signaling_pathway_hsa04066 5 100 0.1643 0.2589
34 Cellular_senescence_hsa04218 7 160 0.1828 0.274
35 FoxO_signaling_pathway_hsa04068 6 132 0.1844 0.274
36 Necroptosis_hsa04217 7 164 0.1986 0.2869
37 Hippo_signaling_pathway_multiple_species_hsa04392 2 29 0.2045 0.2875
38 Wnt_signaling_pathway_hsa04310 6 146 0.2488 0.3405
39 Sphingolipid_signaling_pathway_hsa04071 5 118 0.2568 0.3425
40 Phosphatidylinositol_signaling_system_hsa04070 4 99 0.3222 0.4189
41 Hedgehog_signaling_pathway_hsa04340 2 47 0.3965 0.5029
42 ErbB_signaling_pathway_hsa04012 3 85 0.4481 0.5547
43 Gap_junction_hsa04540 3 88 0.4707 0.5692
44 Jak_STAT_signaling_pathway_hsa04630 5 162 0.5059 0.5926
45 VEGF_signaling_pathway_hsa04370 2 59 0.5128 0.5926
46 Neuroactive_ligand_receptor_interaction_hsa04080 8 278 0.5569 0.6295
47 Peroxisome_hsa04146 2 83 0.6973 0.74
48 Apelin_signaling_pathway_hsa04371 3 137 0.7622 0.7927

Quest ID: 965dc07b5410ba4605e11a170e9d7ba2