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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-495-3p ACTR3 -0.82 0.09306 -0.38 0.11577 mirMAP -0.16 1.0E-5 NA
2 hsa-miR-495-3p ADAM28 -0.82 0.09306 -0.09 0.91558 mirMAP -0.52 1.0E-5 NA
3 hsa-miR-495-3p ADAMTS6 -0.82 0.09306 -0.23 0.67765 mirMAP -0.31 0.00021 NA
4 hsa-miR-495-3p ADSS -0.82 0.09306 0.42 0.08166 mirMAP -0.11 0.00145 NA
5 hsa-miR-495-3p AHNAK -0.82 0.09306 0.37 0.3332 mirMAP -0.17 0.00261 NA
6 hsa-miR-495-3p AIFM2 -0.82 0.09306 0.03 0.90293 MirTarget -0.13 0.00046 NA
7 hsa-miR-495-3p ALOX5AP -0.82 0.09306 -1.55 0.00886 MirTarget -0.18 0.04741 NA
8 hsa-miR-495-3p ANO6 -0.82 0.09306 0.05 0.90255 mirMAP -0.16 0.00337 NA
9 hsa-miR-495-3p ANTXR1 -0.82 0.09306 -0.08 0.90778 MirTarget -0.2 0.04876 NA
10 hsa-miR-495-3p ARHGAP12 -0.82 0.09306 0.37 0.2122 mirMAP -0.11 0.0115 NA
11 hsa-miR-495-3p ARHGAP26 -0.82 0.09306 0.27 0.55575 MirTarget -0.21 0.00221 NA
12 hsa-miR-495-3p ARHGEF35 -0.82 0.09306 0.62 0.24196 mirMAP -0.19 0.02072 NA
13 hsa-miR-495-3p ASS1 -0.82 0.09306 1.06 0.04952 mirMAP -0.17 0.03507 NA
14 hsa-miR-495-3p ATF7IP2 -0.82 0.09306 -0.26 0.60616 MirTarget -0.29 0.00012 NA
15 hsa-miR-495-3p ATL3 -0.82 0.09306 0.39 0.29173 mirMAP -0.26 0 NA
16 hsa-miR-495-3p AVL9 -0.82 0.09306 0.42 0.15753 mirMAP -0.15 0.00042 NA
17 hsa-miR-495-3p B4GALT1 -0.82 0.09306 -0.2 0.59693 mirMAP -0.15 0.0075 NA
18 hsa-miR-495-3p BACH1 -0.82 0.09306 -0.17 0.61746 mirMAP -0.11 0.03183 NA
19 hsa-miR-495-3p BAIAP2L1 -0.82 0.09306 1.94 0.00029 mirMAP -0.18 0.03145 NA
20 hsa-miR-495-3p BCAS1 -0.82 0.09306 3.1 0.00836 mirMAP -0.92 0 NA
21 hsa-miR-495-3p BCAT1 -0.82 0.09306 -0.37 0.61191 MirTarget -0.44 6.0E-5 NA
22 hsa-miR-495-3p BCL11B -0.82 0.09306 -0.34 0.59949 mirMAP -0.27 0.0048 NA
23 hsa-miR-495-3p BCL9L -0.82 0.09306 0.28 0.39221 mirMAP -0.15 0.00225 NA
24 hsa-miR-495-3p BMP7 -0.82 0.09306 1.27 0.13336 MirTarget -0.28 0.02948 NA
25 hsa-miR-495-3p BNIP2 -0.82 0.09306 -0.4 0.1487 MirTarget -0.14 0.00054 NA
26 hsa-miR-495-3p BRIP1 -0.82 0.09306 0.32 0.61306 mirMAP -0.2 0.03334 NA
27 hsa-miR-495-3p BUB1 -0.82 0.09306 0.75 0.2317 MirTarget -0.39 3.0E-5 NA
28 hsa-miR-495-3p C10orf55 -0.82 0.09306 -0.1 0.88633 mirMAP -0.36 0.00092 NA
29 hsa-miR-495-3p C1GALT1 -0.82 0.09306 1.1 0.00171 mirMAP -0.13 0.017 NA
30 hsa-miR-495-3p CBLB -0.82 0.09306 -0.33 0.19169 mirMAP -0.13 0.00028 NA
31 hsa-miR-495-3p CCDC6 -0.82 0.09306 -0.08 0.72287 MirTarget; mirMAP -0.14 5.0E-5 NA
32 hsa-miR-495-3p CCND1 -0.82 0.09306 1.04 0.01709 MirTarget -0.22 0.00064 NA
33 hsa-miR-495-3p CDCP1 -0.82 0.09306 1.81 0.00037 mirMAP -0.24 0.00202 NA
34 hsa-miR-495-3p CDH11 -0.82 0.09306 -0.6 0.41785 mirMAP -0.32 0.00344 NA
35 hsa-miR-495-3p CDK2 -0.82 0.09306 0.04 0.88843 mirMAP -0.15 0.00034 NA
36 hsa-miR-495-3p CHST11 -0.82 0.09306 -0.44 0.42142 mirMAP -0.23 0.00503 NA
37 hsa-miR-495-3p CLDN1 -0.82 0.09306 0.46 0.53058 mirMAP -0.39 0.00038 NA
38 hsa-miR-495-3p CLDN10 -0.82 0.09306 0.73 0.62788 MirTarget -0.64 0.0052 NA
39 hsa-miR-495-3p CLIC4 -0.82 0.09306 -0.37 0.38824 MirTarget -0.13 0.03725 NA
40 hsa-miR-495-3p CORO1C -0.82 0.09306 -0.17 0.56501 mirMAP -0.13 0.0043 NA
41 hsa-miR-495-3p CRIM1 -0.82 0.09306 -0.2 0.57825 MirTarget -0.12 0.02379 NA
42 hsa-miR-495-3p CRLS1 -0.82 0.09306 0.3 0.23234 mirMAP -0.12 0.00124 NA
43 hsa-miR-495-3p CRYBG3 -0.82 0.09306 -0.21 0.58758 mirMAP -0.22 0.00012 NA
44 hsa-miR-495-3p CTSC -0.82 0.09306 -0.3 0.46735 mirMAP -0.2 0.00086 NA
45 hsa-miR-495-3p CTSS -0.82 0.09306 -0.88 0.08984 MirTarget -0.32 3.0E-5 NA
46 hsa-miR-495-3p DCBLD1 -0.82 0.09306 0.3 0.32386 mirMAP -0.13 0.00406 NA
47 hsa-miR-495-3p DIAPH2 -0.82 0.09306 0.37 0.26798 mirMAP -0.22 1.0E-5 NA
48 hsa-miR-495-3p DIO2 -0.82 0.09306 1.45 0.03366 mirMAP -0.44 2.0E-5 NA
49 hsa-miR-495-3p DNAH3 -0.82 0.09306 3.1 0.00111 mirMAP -0.56 8.0E-5 NA
50 hsa-miR-495-3p DRP2 -0.82 0.09306 -0.24 0.77332 mirMAP -0.36 0.00335 NA
51 hsa-miR-495-3p DSC3 -0.82 0.09306 1.79 0.11557 mirMAP -0.45 0.00902 NA
52 hsa-miR-495-3p DTL -0.82 0.09306 1.01 0.05737 MirTarget -0.29 0.00024 NA
53 hsa-miR-495-3p DTX2 -0.82 0.09306 0.28 0.48528 mirMAP -0.17 0.0048 NA
54 hsa-miR-495-3p DTX3L -0.82 0.09306 -0.01 0.97903 mirMAP -0.17 1.0E-5 NA
55 hsa-miR-495-3p DTX4 -0.82 0.09306 0.43 0.27683 mirMAP -0.22 0.00023 NA
56 hsa-miR-495-3p DUSP4 -0.82 0.09306 1.3 0.01012 mirMAP -0.21 0.00658 NA
57 hsa-miR-495-3p EIF3H -0.82 0.09306 0.15 0.51283 mirMAP -0.1 0.00214 NA
58 hsa-miR-495-3p EIF3M -0.82 0.09306 0.1 0.64648 mirMAP -0.11 0.00032 NA
59 hsa-miR-495-3p EIF5A2 -0.82 0.09306 0.39 0.27731 mirMAP -0.22 6.0E-5 NA
60 hsa-miR-495-3p EML4 -0.82 0.09306 -0.29 0.25575 MirTarget; mirMAP -0.12 0.00095 NA
61 hsa-miR-495-3p ENC1 -0.82 0.09306 -0.13 0.79858 mirMAP -0.33 1.0E-5 NA
62 hsa-miR-495-3p ETV5 -0.82 0.09306 0.15 0.61762 MirTarget -0.11 0.01397 NA
63 hsa-miR-495-3p FAM49A -0.82 0.09306 -1.66 0.0067 mirMAP -0.19 0.04225 NA
64 hsa-miR-495-3p FARP1 -0.82 0.09306 -0.14 0.63715 MirTarget -0.18 2.0E-5 NA
65 hsa-miR-495-3p FBXO28 -0.82 0.09306 0.35 0.09605 mirMAP -0.12 0.00015 NA
66 hsa-miR-495-3p FERMT1 -0.82 0.09306 2.37 0.00699 mirMAP -0.73 0 NA
67 hsa-miR-495-3p FGD6 -0.82 0.09306 0.26 0.6034 MirTarget -0.31 3.0E-5 NA
68 hsa-miR-495-3p FMO5 -0.82 0.09306 0.76 0.34108 MirTarget -0.26 0.02746 NA
69 hsa-miR-495-3p FNDC1 -0.82 0.09306 0.23 0.80322 MirTarget -0.32 0.02368 NA
70 hsa-miR-495-3p FNDC3B -0.82 0.09306 0.21 0.56856 mirMAP -0.13 0.02404 NA
71 hsa-miR-495-3p FOSL2 -0.82 0.09306 0.14 0.73953 mirMAP -0.21 0.00074 NA
72 hsa-miR-495-3p FOXD1 -0.82 0.09306 1.78 0.08662 mirMAP -0.33 0.03609 NA
73 hsa-miR-495-3p FOXL1 -0.82 0.09306 2.96 0.00072 mirMAP -0.41 0.00194 NA
74 hsa-miR-495-3p FREM2 -0.82 0.09306 0.19 0.85046 mirMAP -0.5 0.00091 NA
75 hsa-miR-495-3p FUT4 -0.82 0.09306 -0.09 0.82434 mirMAP -0.15 0.00803 NA
76 hsa-miR-495-3p GABPB2 -0.82 0.09306 0.59 0.05911 mirMAP -0.1 0.02676 NA
77 hsa-miR-495-3p GAN -0.82 0.09306 0.77 0.0867 mirMAP -0.22 0.00093 NA
78 hsa-miR-495-3p GBP4 -0.82 0.09306 -0.39 0.44108 mirMAP -0.27 0.00046 NA
79 hsa-miR-495-3p GDA -0.82 0.09306 2.64 0.01236 mirMAP -0.59 0.00022 NA
80 hsa-miR-495-3p GFOD1 -0.82 0.09306 -0.39 0.30845 mirMAP -0.12 0.02921 NA
81 hsa-miR-495-3p GINS4 -0.82 0.09306 0.06 0.87885 mirMAP -0.13 0.03281 NA
82 hsa-miR-495-3p GM2A -0.82 0.09306 -1.01 0.00074 mirMAP -0.1 0.02422 NA
83 hsa-miR-495-3p GPRC5A -0.82 0.09306 3.96 0.00162 MirTarget -1.08 0 NA
84 hsa-miR-495-3p GTF2E2 -0.82 0.09306 0.25 0.2962 MirTarget -0.15 2.0E-5 NA
85 hsa-miR-495-3p H1F0 -0.82 0.09306 0.91 0.01772 mirMAP -0.18 0.00145 NA
86 hsa-miR-495-3p HELLS -0.82 0.09306 0.63 0.16518 mirMAP -0.26 9.0E-5 NA
87 hsa-miR-495-3p HJURP -0.82 0.09306 0.97 0.15968 MirTarget -0.44 2.0E-5 NA
88 hsa-miR-495-3p HMGA2 -0.82 0.09306 2.01 0.08779 mirMAP -0.61 0.00058 NA
89 hsa-miR-495-3p HNF4G -0.82 0.09306 1.73 0.03018 MirTarget -0.41 0.00077 NA
90 hsa-miR-495-3p HOXC8 -0.82 0.09306 1.05 0.26931 mirMAP -0.28 0.04905 NA
91 hsa-miR-495-3p HTR1D -0.82 0.09306 2.82 0.00062 mirMAP -0.27 0.03413 NA
92 hsa-miR-495-3p ICK -0.82 0.09306 0.03 0.92808 mirMAP -0.11 0.01333 NA
93 hsa-miR-495-3p IDE -0.82 0.09306 0.09 0.79323 mirMAP -0.17 0.00135 NA
94 hsa-miR-495-3p IKZF2 -0.82 0.09306 -0.36 0.39635 mirMAP -0.14 0.03177 NA
95 hsa-miR-495-3p IL1R1 -0.82 0.09306 -0.11 0.83972 mirMAP -0.18 0.03409 NA
96 hsa-miR-495-3p INPP4B -0.82 0.09306 0.94 0.1115 MirTarget -0.39 1.0E-5 NA
97 hsa-miR-495-3p ITGA2 -0.82 0.09306 0.8 0.18125 mirMAP -0.26 0.00447 NA
98 hsa-miR-495-3p ITGAV -0.82 0.09306 -0.33 0.42648 mirMAP -0.18 0.00412 NA
99 hsa-miR-495-3p ITGB3 -0.82 0.09306 -0.6 0.34475 mirMAP -0.19 0.04326 NA
100 hsa-miR-495-3p ITGB5 -0.82 0.09306 0.61 0.11874 MirTarget -0.22 0.00021 NA
101 hsa-miR-495-3p IYD -0.82 0.09306 3.23 0.01005 mirMAP -0.82 1.0E-5 NA
102 hsa-miR-495-3p KANK2 -0.82 0.09306 -0.09 0.80631 mirMAP -0.11 0.03941 NA
103 hsa-miR-495-3p KANK4 -0.82 0.09306 -1.19 0.22903 MirTarget -0.4 0.00756 NA
104 hsa-miR-495-3p KIAA1217 -0.82 0.09306 0.15 0.72848 mirMAP -0.33 0 NA
105 hsa-miR-495-3p KIF13B -0.82 0.09306 0.48 0.16805 mirMAP -0.14 0.00687 NA
106 hsa-miR-495-3p KLF3 -0.82 0.09306 0.42 0.13439 mirMAP -0.15 0.00042 NA
107 hsa-miR-495-3p KLK10 -0.82 0.09306 4.59 0.00205 MirTarget -1.16 0 NA
108 hsa-miR-495-3p LANCL3 -0.82 0.09306 1.8 0.00736 mirMAP -0.41 5.0E-5 NA
109 hsa-miR-495-3p LGALS8 -0.82 0.09306 -0.21 0.33877 mirMAP -0.11 0.00063 NA
110 hsa-miR-495-3p LHFPL2 -0.82 0.09306 -0.42 0.26451 mirMAP -0.12 0.036 NA
111 hsa-miR-495-3p LPP -0.82 0.09306 0.05 0.92861 mirMAP -0.36 1.0E-5 NA
112 hsa-miR-495-3p LRRK1 -0.82 0.09306 -0.75 0.07328 MirTarget -0.22 0.00048 NA
113 hsa-miR-495-3p LYPD6 -0.82 0.09306 0.45 0.54131 MirTarget -0.25 0.02456 NA
114 hsa-miR-495-3p MACC1 -0.82 0.09306 0.54 0.4139 mirMAP -0.37 0.00014 NA
115 hsa-miR-495-3p MALL -0.82 0.09306 2 0.00509 MirTarget -0.4 0.00025 NA
116 hsa-miR-495-3p MBOAT2 -0.82 0.09306 1.25 0.01215 mirMAP -0.24 0.0015 NA
117 hsa-miR-495-3p MDFIC -0.82 0.09306 -0.75 0.12581 mirMAP -0.25 0.00076 NA
118 hsa-miR-495-3p MIPOL1 -0.82 0.09306 0.93 0.01754 mirMAP -0.12 0.03929 NA
119 hsa-miR-495-3p MITF -0.82 0.09306 0.09 0.87072 mirMAP -0.27 0.00062 NA
120 hsa-miR-495-3p MKI67 -0.82 0.09306 0.78 0.23091 mirMAP -0.42 1.0E-5 NA
121 hsa-miR-495-3p MOCOS -0.82 0.09306 1.19 0.07323 mirMAP -0.49 0 NA
122 hsa-miR-495-3p MOSPD2 -0.82 0.09306 -0.25 0.43528 MirTarget; mirMAP -0.11 0.02897 NA
123 hsa-miR-495-3p MRPS17 -0.82 0.09306 0.57 0.04298 mirMAP -0.13 0.00288 NA
124 hsa-miR-495-3p MTHFD2 -0.82 0.09306 0.17 0.59287 mirMAP -0.13 0.00805 NA
125 hsa-miR-495-3p MXD1 -0.82 0.09306 0.52 0.30022 mirMAP -0.16 0.03807 NA
126 hsa-miR-495-3p MYO1E -0.82 0.09306 0.07 0.86409 mirMAP -0.21 0.0003 NA
127 hsa-miR-495-3p NCEH1 -0.82 0.09306 -0.38 0.37338 mirMAP -0.22 0.00067 NA
128 hsa-miR-495-3p NCF2 -0.82 0.09306 -1.7 0.00657 MirTarget -0.29 0.0022 NA
129 hsa-miR-495-3p NEDD4 -0.82 0.09306 -0.13 0.70772 MirTarget; mirMAP -0.13 0.01144 NA
130 hsa-miR-495-3p NIP7 -0.82 0.09306 0.22 0.33409 mirMAP -0.15 1.0E-5 NA
131 hsa-miR-495-3p NIPAL1 -0.82 0.09306 0.84 0.27056 mirMAP -0.26 0.02625 NA
132 hsa-miR-495-3p NOTCH2 -0.82 0.09306 -1.05 0.03489 MirTarget -0.25 0.00076 NA
133 hsa-miR-495-3p NRIP3 -0.82 0.09306 0.09 0.87063 mirMAP -0.18 0.03123 NA
134 hsa-miR-495-3p OAS2 -0.82 0.09306 -0.09 0.88123 mirMAP -0.45 0 NA
135 hsa-miR-495-3p OCLN -0.82 0.09306 1 0.05249 mirMAP -0.15 0.04839 NA
136 hsa-miR-495-3p OPN3 -0.82 0.09306 -0.56 0.15578 MirTarget -0.2 0.00083 NA
137 hsa-miR-495-3p OSMR -0.82 0.09306 0.18 0.7299 mirMAP -0.29 0.00027 NA
138 hsa-miR-495-3p PAK2 -0.82 0.09306 -0.07 0.75715 mirMAP -0.11 0.00052 NA
139 hsa-miR-495-3p PAQR5 -0.82 0.09306 0.18 0.79167 mirMAP -0.21 0.0464 NA
140 hsa-miR-495-3p PARD3B -0.82 0.09306 0.01 0.98353 mirMAP -0.21 0.04312 NA
141 hsa-miR-495-3p PCSK5 -0.82 0.09306 0.31 0.60344 mirMAP -0.26 0.00331 NA
142 hsa-miR-495-3p PDE7A -0.82 0.09306 -1.34 0.00215 mirMAP -0.15 0.02506 NA
143 hsa-miR-495-3p PIP4K2A -0.82 0.09306 -0.91 0.00573 mirMAP -0.11 0.03612 NA
144 hsa-miR-495-3p PKHD1 -0.82 0.09306 -0.13 0.92023 mirMAP -0.45 0.02147 NA
145 hsa-miR-495-3p PLAG1 -0.82 0.09306 -0.32 0.66572 mirMAP -0.27 0.01473 NA
146 hsa-miR-495-3p POU2F3 -0.82 0.09306 0.78 0.4714 mirMAP -0.76 0 NA
147 hsa-miR-495-3p POU5F1 -0.82 0.09306 0.58 0.55304 mirMAP -0.43 0.00326 NA
148 hsa-miR-495-3p PPP1R3B -0.82 0.09306 0.11 0.76607 mirMAP -0.2 0.00037 NA
149 hsa-miR-495-3p PPP4C -0.82 0.09306 0.29 0.26841 MirTarget -0.14 0.00055 NA
150 hsa-miR-495-3p PRKCA -0.82 0.09306 0.29 0.37471 mirMAP -0.1 0.04162 NA
NumGOOverlapSizeP ValueAdj. P Value
1 TISSUE DEVELOPMENT 48 1518 1.367e-10 6.362e-07
2 UROGENITAL SYSTEM DEVELOPMENT 17 299 8.299e-08 0.0001931
3 EPITHELIUM DEVELOPMENT 31 945 1.771e-07 0.0002747
4 REGULATION OF CELL DIFFERENTIATION 40 1492 5.278e-07 0.000614
5 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 30 957 7.401e-07 0.0006887
6 EPITHELIAL CELL DIFFERENTIATION 20 495 1.442e-06 0.0008802
7 CELL DEVELOPMENT 38 1426 1.233e-06 0.0008802
8 CARDIOVASCULAR SYSTEM DEVELOPMENT 26 788 1.702e-06 0.0008802
9 CIRCULATORY SYSTEM DEVELOPMENT 26 788 1.702e-06 0.0008802
10 VASCULATURE DEVELOPMENT 19 469 2.565e-06 0.001193
11 IMMUNE SYSTEM PROCESS 46 1984 3.732e-06 0.001464
12 INTERACTION WITH HOST 10 134 3.776e-06 0.001464
13 FORMATION OF PRIMARY GERM LAYER 9 110 5.474e-06 0.001952
14 BLOOD VESSEL MORPHOGENESIS 16 364 5.874e-06 0.001952
15 BIOLOGICAL ADHESION 29 1032 9.688e-06 0.003005
16 CELL JUNCTION ORGANIZATION 11 185 1.107e-05 0.00322
17 TISSUE MORPHOGENESIS 19 533 1.582e-05 0.003346
18 GASTRULATION 10 155 1.374e-05 0.003346
19 LOCOMOTION 30 1114 1.524e-05 0.003346
20 MESENCHYME DEVELOPMENT 11 190 1.423e-05 0.003346
21 STEM CELL DIFFERENTIATION 11 190 1.423e-05 0.003346
22 REGULATION OF CELL DEVELOPMENT 25 836 1.49e-05 0.003346
23 STEM CELL DIVISION 5 29 1.903e-05 0.00385
24 REGULATION OF EPITHELIAL CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 4 15 2.178e-05 0.004223
25 REGULATION OF CELL PROLIFERATION 36 1496 2.325e-05 0.004328
26 SKELETAL SYSTEM DEVELOPMENT 17 455 2.482e-05 0.004415
27 TUBE DEVELOPMENT 19 552 2.562e-05 0.004415
28 POSITIVE REGULATION OF CELL PROLIFERATION 24 814 2.798e-05 0.00465
29 SKIN DEVELOPMENT 11 211 3.756e-05 0.006026
30 CELL PROLIFERATION 21 672 3.958e-05 0.006138
31 REGULATION OF KIDNEY DEVELOPMENT 6 55 4.118e-05 0.006181
32 EMBRYO DEVELOPMENT 25 894 4.505e-05 0.006551
33 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 38 1672 4.683e-05 0.006603
34 REGULATION OF STEM CELL DIFFERENTIATION 8 113 5.224e-05 0.007149
35 EPITHELIAL CELL DEVELOPMENT 10 186 6.55e-05 0.008708
36 MORPHOGENESIS OF AN EPITHELIUM 15 400 7.192e-05 0.009295
37 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 31 1275 7.579e-05 0.00953
NumGOOverlapSizeP ValueAdj. P Value
1 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 22 629 4.476e-06 0.004158
NumGOOverlapSizeP ValueAdj. P Value
1 CELL JUNCTION 33 1151 1.427e-06 0.0004166
2 ANCHORING JUNCTION 20 489 1.195e-06 0.0004166
3 CELL CELL JUNCTION 16 383 1.11e-05 0.002161
4 CELL SUBSTRATE JUNCTION 15 398 6.799e-05 0.009927

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04390_Hippo_signaling_pathway 9 154 8.031e-05 0.01446
2 hsa04512_ECM.receptor_interaction 6 85 0.0004654 0.02231
3 hsa04145_Phagosome 8 156 0.0004837 0.02231
4 hsa04510_Focal_adhesion 9 200 0.0005642 0.02231
5 hsa04110_Cell_cycle 7 128 0.0007438 0.02231
6 hsa04380_Osteoclast_differentiation 7 128 0.0007438 0.02231
7 hsa04330_Notch_signaling_pathway 4 47 0.002129 0.05474
8 hsa04151_PI3K_AKT_signaling_pathway 11 351 0.002756 0.06201
9 hsa04310_Wnt_signaling_pathway 6 151 0.008444 0.1689
10 hsa04114_Oocyte_meiosis 5 114 0.01063 0.1763
11 hsa04670_Leukocyte_transendothelial_migration 5 117 0.0118 0.1763
12 hsa04810_Regulation_of_actin_cytoskeleton 7 214 0.01266 0.1763
13 hsa00533_Glycosaminoglycan_biosynthesis_._keratan_sulfate 2 15 0.01274 0.1763
14 hsa00514_Other_types_of_O.glycan_biosynthesis 3 46 0.01621 0.2063
15 hsa04350_TGF.beta_signaling_pathway 4 85 0.0172 0.2063
16 hsa04012_ErbB_signaling_pathway 4 87 0.01857 0.2069
17 hsa04530_Tight_junction 5 133 0.01954 0.2069
18 hsa04514_Cell_adhesion_molecules_.CAMs. 5 136 0.02129 0.2129
19 hsa04340_Hedgehog_signaling_pathway 3 56 0.02722 0.2579
20 hsa04916_Melanogenesis 4 101 0.03009 0.2708
21 hsa00601_Glycosphingolipid_biosynthesis_._lacto_and_neolacto_series 2 26 0.03627 0.3109
22 hsa00512_Mucin_type_O.Glycan_biosynthesis 2 30 0.04711 0.3855
23 hsa00250_Alanine._aspartate_and_glutamate_metabolism 2 32 0.05292 0.4142
24 hsa04070_Phosphatidylinositol_signaling_system 3 78 0.06223 0.4667
25 hsa04914_Progesterone.mediated_oocyte_maturation 3 87 0.08052 0.5663
26 hsa04640_Hematopoietic_cell_lineage 3 88 0.08268 0.5663
27 hsa04540_Gap_junction 3 90 0.08708 0.5663
28 hsa04144_Endocytosis 5 203 0.08809 0.5663
29 hsa04010_MAPK_signaling_pathway 6 268 0.0927 0.5754
30 hsa04630_Jak.STAT_signaling_pathway 4 155 0.1065 0.639
31 hsa00510_N.Glycan_biosynthesis 2 49 0.1106 0.6423
32 hsa00562_Inositol_phosphate_metabolism 2 57 0.1416 0.7496
33 hsa04142_Lysosome 3 121 0.1661 0.8069
34 hsa04115_p53_signaling_pathway 2 69 0.1908 0.8339
35 hsa04360_Axon_guidance 3 130 0.192 0.8339
36 hsa04720_Long.term_potentiation 2 70 0.195 0.8339
37 hsa04976_Bile_secretion 2 71 0.1992 0.8339
38 hsa04520_Adherens_junction 2 73 0.2077 0.8412
39 hsa04971_Gastric_acid_secretion 2 74 0.2119 0.8412
40 hsa04910_Insulin_signaling_pathway 3 138 0.2159 0.8412
41 hsa04370_VEGF_signaling_pathway 2 76 0.2204 0.8412
42 hsa04612_Antigen_processing_and_presentation 2 78 0.229 0.8412
43 hsa00564_Glycerophospholipid_metabolism 2 80 0.2376 0.8552
44 hsa04210_Apoptosis 2 89 0.2762 0.9208
45 hsa04970_Salivary_secretion 2 89 0.2762 0.9208
46 hsa00230_Purine_metabolism 3 162 0.2903 0.9502
47 hsa04912_GnRH_signaling_pathway 2 101 0.3276 1
48 hsa04660_T_cell_receptor_signaling_pathway 2 108 0.3571 1
49 hsa04270_Vascular_smooth_muscle_contraction 2 116 0.3903 1
50 hsa04120_Ubiquitin_mediated_proteolysis 2 139 0.4809 1
51 hsa04014_Ras_signaling_pathway 3 236 0.5176 1
52 hsa04020_Calcium_signaling_pathway 2 177 0.611 1
53 hsa04062_Chemokine_signaling_pathway 2 189 0.6467 1

Quest ID: 9790df6ab151e47b30aa747885e3c214