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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-148a-3p A4GNT -0.75 0 -1.24 0.00042 MirTarget -0.73 0 NA
2 hsa-miR-20b-5p AADAC 0.46 0.02859 -1.53 0 MirTarget -0.22 0.0029 NA
3 hsa-miR-27b-3p AAGAB -0.82 0 0.45 0 MirTarget -0.13 0 NA
4 hsa-miR-455-3p AAK1 -1.4 0 0.62 0 PITA -0.2 0 NA
5 hsa-miR-146b-5p AASS 0.42 0.04574 -1.86 0 miRanda -0.17 0.01702 NA
6 hsa-miR-182-5p AASS 1.97 0 -1.86 0 MirTarget -0.24 0 NA
7 hsa-miR-21-5p ABAT 1.51 0 -2.16 0 MirTarget -0.93 0 NA
8 hsa-miR-21-5p ABCA1 1.51 0 -1.1 0 mirMAP -0.29 0 NA
9 hsa-miR-21-5p ABCA10 1.51 0 -1.06 4.0E-5 mirMAP -0.45 0 NA
10 hsa-miR-455-5p ABCA4 -0.27 0.05813 0.73 0.00376 miRanda -0.22 0.01277 NA
11 hsa-miR-181a-5p ABCA5 0.25 0.05519 -0.14 0.30791 mirMAP -0.26 0 NA
12 hsa-miR-181b-5p ABCA5 0.49 0.00105 -0.14 0.30791 mirMAP -0.26 0 NA
13 hsa-miR-29c-3p ABCC5 -1.44 0 1.23 0 mirMAP -0.28 0 NA
14 hsa-miR-409-3p ABCC9 -0.5 0.05268 -2.33 0 mirMAP -0.19 0.00056 NA
15 hsa-miR-21-5p ABCD3 1.51 0 -0.9 0 miRNAWalker2 validate -0.38 0 NA
16 hsa-miR-455-5p ABCE1 -0.27 0.05813 -0.37 0 miRanda -0.1 0.00012 NA
17 hsa-miR-224-3p ABCG2 1.41 0 -1.71 0 mirMAP -0.14 0.01775 NA
18 hsa-miR-181b-5p ABHD13 0.49 0.00105 -0.68 0 MirTarget -0.11 0.00024 NA
19 hsa-miR-181b-5p ABHD15 0.49 0.00105 -1.3 0 mirMAP -0.44 0 NA
20 hsa-miR-19b-3p ABHD2 0.6 0.00017 -1.2 0 mirMAP -0.24 0 NA
21 hsa-miR-20a-5p ABHD2 0.85 0 -1.2 0 miRNATAP -0.28 0 NA
22 hsa-miR-20b-5p ABHD2 0.46 0.02859 -1.2 0 miRNATAP -0.14 0.00018 NA
23 hsa-miR-19b-3p ABHD5 0.6 0.00017 -0.6 0 miRNAWalker2 validate -0.11 0.0002 NA
24 hsa-miR-20a-5p ABHD5 0.85 0 -0.6 0 MirTarget -0.12 1.0E-5 NA
25 hsa-miR-192-3p ABL2 -0.64 0.00027 0.6 0 MirTarget -0.13 0 NA
26 hsa-miR-30e-5p ABL2 -0.63 0 0.6 0 mirMAP -0.18 5.0E-5 NA
27 hsa-miR-34a-5p ABLIM3 1.04 0 -1.27 0 miRNATAP -0.16 0.0091 NA
28 hsa-miR-455-5p ABLIM3 -0.27 0.05813 -1.27 0 miRanda -0.14 0.01683 NA
29 hsa-miR-30e-5p ABR -0.63 0 -0.28 0.11187 mirMAP -0.25 0.00305 NA
30 hsa-miR-34a-5p ABR 1.04 0 -0.28 0.11187 miRNATAP -0.19 0.00227 NA
31 hsa-miR-181a-5p ABTB2 0.25 0.05519 -0.43 0.0031 MirTarget; miRNATAP -0.31 0 NA
32 hsa-miR-181b-5p ABTB2 0.49 0.00105 -0.43 0.0031 MirTarget; miRNATAP -0.34 0 NA
33 hsa-miR-181a-5p ACAD8 0.25 0.05519 -0.52 0 MirTarget -0.14 6.0E-5 NA
34 hsa-miR-181b-5p ACAD8 0.49 0.00105 -0.52 0 MirTarget -0.15 0 NA
35 hsa-miR-182-5p ACADSB 1.97 0 -2.11 0 mirMAP -0.26 0 NA
36 hsa-miR-224-3p ACADSB 1.41 0 -2.11 0 mirMAP -0.16 0.00024 NA
37 hsa-miR-455-3p ACAN -1.4 0 2.72 0 MirTarget; miRNATAP -0.82 0 NA
38 hsa-miR-21-5p ACAT1 1.51 0 -1.62 0 miRNAWalker2 validate -0.62 0 NA
39 hsa-miR-19b-3p ACBD5 0.6 0.00017 -0.75 0 MirTarget; miRNATAP -0.17 0 NA
40 hsa-miR-21-5p ACBD5 1.51 0 -0.75 0 miRNAWalker2 validate; miRNATAP -0.33 0 NA
41 hsa-miR-455-5p ACER2 -0.27 0.05813 -1.22 0 miRanda -0.32 4.0E-5 NA
42 hsa-miR-20a-5p ACER3 0.85 0 0.02 0.84604 mirMAP -0.12 2.0E-5 NA
43 hsa-miR-30b-5p ACER3 -0.54 2.0E-5 0.02 0.84604 miRNAWalker2 validate -0.13 0.00054 NA
44 hsa-miR-148a-3p ACHE -0.75 0 0.07 0.84522 miRNATAP -0.64 0 NA
45 hsa-miR-194-5p ACHE -0.29 0.09961 0.07 0.84522 MirTarget -0.38 4.0E-5 NA
46 hsa-miR-146b-5p ACO1 0.42 0.04574 -0.9 0 miRanda -0.12 9.0E-5 NA
47 hsa-miR-181a-5p ACOT12 0.25 0.05519 -2.27 0 miRNAWalker2 validate -0.85 0 NA
48 hsa-miR-15a-5p ACOX1 0.35 0.00077 -1.16 0 miRNATAP -0.3 2.0E-5 NA
49 hsa-miR-20a-5p ACOX1 0.85 0 -1.16 0 mirMAP -0.15 0.00046 NA
50 hsa-miR-20b-5p ACOX1 0.46 0.02859 -1.16 0 mirMAP -0.17 0 NA
51 hsa-miR-192-5p ACPP -0.5 0.00345 -0.47 0.14269 MirTarget -0.44 0 NA
52 hsa-miR-181a-5p ACSL1 0.25 0.05519 -2.33 0 MirTarget -0.6 0 NA
53 hsa-miR-181b-5p ACSL1 0.49 0.00105 -2.33 0 MirTarget -0.69 0 NA
54 hsa-miR-30c-5p ACSL3 -0.43 0.00016 0.05 0.65044 mirMAP -0.16 0.00032 NA
55 hsa-miR-30e-5p ACSL3 -0.63 0 0.05 0.65044 mirMAP -0.15 0.00409 NA
56 hsa-miR-148a-3p ACSL4 -0.75 0 2.07 0 miRNATAP -0.65 0 NA
57 hsa-miR-181a-5p ACSL6 0.25 0.05519 0.39 0.26458 miRNATAP -0.7 0 NA
58 hsa-miR-181b-5p ACSL6 0.49 0.00105 0.39 0.26458 miRNATAP -0.75 0 NA
59 hsa-miR-20a-5p ACSL6 0.85 0 0.39 0.26458 mirMAP -0.21 0.03388 NA
60 hsa-miR-20b-5p ACSL6 0.46 0.02859 0.39 0.26458 mirMAP -0.26 0.0016 NA
61 hsa-miR-127-3p ACSM2A -1.08 2.0E-5 -2.22 0 miRanda -0.14 0.04952 NA
62 hsa-miR-192-3p ACSS1 -0.64 0.00027 0.29 0.18285 mirMAP -0.35 0 NA
63 hsa-miR-34a-5p ACSS1 1.04 0 0.29 0.18285 miRNAWalker2 validate -0.23 0.00217 NA
64 hsa-miR-181a-5p ACSS3 0.25 0.05519 -1.23 0.00019 MirTarget -0.95 0 NA
65 hsa-miR-181b-5p ACSS3 0.49 0.00105 -1.23 0.00019 MirTarget -1 0 NA
66 hsa-miR-192-3p ACTB -0.64 0.00027 -0.06 0.43313 MirTarget -0.11 0 NA
67 hsa-miR-29c-3p ACTN4 -1.44 0 0.36 0 mirMAP -0.13 0 NA
68 hsa-miR-30c-5p ACTR1A -0.43 0.00016 0.16 0.02153 miRNATAP -0.11 9.0E-5 NA
69 hsa-miR-192-3p ACTR3 -0.64 0.00027 0.05 0.43435 MirTarget -0.12 0 NA
70 hsa-miR-194-5p ACTR3 -0.29 0.09961 0.05 0.43435 mirMAP -0.14 0 NA
71 hsa-miR-455-5p ACTR3 -0.27 0.05813 0.05 0.43435 miRanda -0.14 0 NA
72 hsa-miR-20a-5p ACTR3C 0.85 0 -0.99 0 mirMAP -0.21 1.0E-5 NA
73 hsa-miR-20b-5p ACTR3C 0.46 0.02859 -0.99 0 mirMAP -0.16 3.0E-5 NA
74 hsa-miR-148a-3p ACVR1 -0.75 0 -0.44 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.13 0.0001 NA
75 hsa-miR-181a-5p ACVR1C 0.25 0.05519 -2.2 0 miRNATAP -0.67 0 NA
76 hsa-miR-181b-5p ACVR1C 0.49 0.00105 -2.2 0 miRNATAP -0.67 0 NA
77 hsa-miR-409-3p ACVR1C -0.5 0.05268 -2.2 0 MirTarget -0.1 0.0381 NA
78 hsa-miR-21-5p ACVR2A 1.51 0 -0.55 0 miRNATAP -0.17 0 NA
79 hsa-miR-409-3p ADAL -0.5 0.05268 -0.15 0.22563 mirMAP -0.12 0 NA
80 hsa-miR-148a-3p ADAM10 -0.75 0 -0 0.9783 MirTarget -0.11 0.02275 NA
81 hsa-miR-455-5p ADAM10 -0.27 0.05813 -0 0.9783 miRanda -0.18 0.00053 NA
82 hsa-miR-29c-3p ADAM11 -1.44 0 1.25 0 mirMAP -0.41 0 NA
83 hsa-miR-455-5p ADAM15 -0.27 0.05813 1.18 0 miRanda -0.16 0.00031 NA
84 hsa-miR-148a-3p ADAM19 -0.75 0 -0.32 0.02321 mirMAP -0.33 0 NA
85 hsa-miR-30e-5p ADAM19 -0.63 0 -0.32 0.02321 MirTarget -0.17 0.01281 NA
86 hsa-miR-148a-3p ADAM22 -0.75 0 1.17 0.00038 MirTarget; miRNATAP -0.57 0 NA
87 hsa-miR-29c-3p ADAM22 -1.44 0 1.17 0.00038 miRNATAP -0.46 1.0E-5 NA
88 hsa-miR-34a-5p ADAM22 1.04 0 1.17 0.00038 MirTarget; miRNATAP -0.29 0.00957 NA
89 hsa-miR-455-5p ADAM22 -0.27 0.05813 1.17 0.00038 PITA; miRanda; miRNATAP -0.45 6.0E-5 NA
90 hsa-miR-148a-3p ADAM23 -0.75 0 1.53 0.00013 MirTarget -0.47 0.00032 NA
91 hsa-miR-192-3p ADAM23 -0.64 0.00027 1.53 0.00013 mirMAP -0.43 0.00012 NA
92 hsa-miR-455-5p ADAM28 -0.27 0.05813 -0.45 0.16409 miRanda -0.53 0 NA
93 hsa-miR-20a-5p ADAM9 0.85 0 0.47 0.00581 miRNATAP -0.24 0 NA
94 hsa-miR-27b-3p ADAMTS10 -0.82 0 0.73 0.00187 MirTarget; miRNATAP -0.26 0.01059 NA
95 hsa-miR-505-5p ADAMTS14 -0.77 1.0E-5 1.08 2.0E-5 mirMAP -0.22 0.0012 NA
96 hsa-miR-148a-3p ADAMTS15 -0.75 0 -0.88 0.00206 MirTarget; miRNATAP -0.41 1.0E-5 NA
97 hsa-miR-17-3p ADAMTS15 0.41 0.00422 -0.88 0.00206 MirTarget; miRNATAP -0.42 2.0E-5 NA
98 hsa-miR-192-3p ADAMTS15 -0.64 0.00027 -0.88 0.00206 mirMAP -0.34 2.0E-5 NA
99 hsa-miR-148a-3p ADAMTS18 -0.75 0 1.44 1.0E-5 miRNATAP -0.21 0.04667 NA
100 hsa-miR-455-3p ADAMTS18 -1.4 0 1.44 1.0E-5 PITA -0.26 0.00421 NA
101 hsa-miR-34a-5p ADAMTS2 1.04 0 -2.31 0 MirTarget -0.52 0 NA
102 hsa-miR-148a-3p ADAMTS5 -0.75 0 -0.16 0.36499 miRNATAP -0.31 0 NA
103 hsa-miR-15a-5p ADAMTS5 0.35 0.00077 -0.16 0.36499 miRNATAP -0.2 0.0134 NA
104 hsa-miR-192-3p ADAMTS5 -0.64 0.00027 -0.16 0.36499 mirMAP -0.24 0 NA
105 hsa-miR-194-5p ADAMTS5 -0.29 0.09961 -0.16 0.36499 mirMAP -0.29 0 NA
106 hsa-miR-20a-5p ADAMTS5 0.85 0 -0.16 0.36499 miRNATAP -0.16 0.00122 NA
107 hsa-miR-27b-3p ADAMTS6 -0.82 0 0.7 0.00475 miRNATAP -0.26 0.01567 NA
108 hsa-miR-29c-3p ADAMTS6 -1.44 0 0.7 0.00475 MirTarget; miRNATAP -0.4 0 NA
109 hsa-miR-29c-3p ADAMTS7 -1.44 0 0.91 0 MirTarget; miRNATAP -0.14 0.0037 NA
110 hsa-miR-29c-3p ADAMTS9 -1.44 0 0.8 0 miRNATAP -0.23 3.0E-5 NA
111 hsa-miR-30c-5p ADAMTS9 -0.43 0.00016 0.8 0 miRNATAP -0.19 0.00992 NA
112 hsa-miR-17-3p ADAMTSL1 0.41 0.00422 -0.65 0.00587 mirMAP -0.33 3.0E-5 NA
113 hsa-miR-455-5p ADAMTSL1 -0.27 0.05813 -0.65 0.00587 miRanda -0.19 0.02122 NA
114 hsa-miR-15a-5p ADAMTSL3 0.35 0.00077 -1.86 0 MirTarget -0.47 0.00098 NA
115 hsa-miR-19b-3p ADAMTSL3 0.6 0.00017 -1.86 0 miRNATAP -0.24 0.00865 NA
116 hsa-miR-192-3p ADARB1 -0.64 0.00027 -0.13 0.22208 mirMAP -0.11 0.00011 NA
117 hsa-miR-192-5p ADARB1 -0.5 0.00345 -0.13 0.22208 mirMAP -0.13 3.0E-5 NA
118 hsa-miR-20a-5p ADARB1 0.85 0 -0.13 0.22208 MirTarget -0.11 0.00024 NA
119 hsa-miR-455-5p ADAT1 -0.27 0.05813 -0.15 0.33101 miRanda -0.25 1.0E-5 NA
120 hsa-miR-132-3p ADCY1 0.32 0.00272 -2.7 0 mirMAP -0.61 0.00048 NA
121 hsa-miR-146b-5p ADCY1 0.42 0.04574 -2.7 0 mirMAP -0.41 0 NA
122 hsa-miR-181a-5p ADCY1 0.25 0.05519 -2.7 0 miRNATAP -0.33 0.02257 NA
123 hsa-miR-181b-5p ADCY1 0.49 0.00105 -2.7 0 miRNATAP -0.49 9.0E-5 NA
124 hsa-miR-34a-5p ADCY1 1.04 0 -2.7 0 mirMAP -0.74 0 NA
125 hsa-miR-27b-3p ADCY3 -0.82 0 0.15 0.33929 miRNATAP -0.16 0.01185 NA
126 hsa-miR-15a-5p ADCY5 0.35 0.00077 -1.75 0 MirTarget; miRNATAP -0.63 5.0E-5 NA
127 hsa-miR-27b-3p ADCY6 -0.82 0 1.25 0 MirTarget; miRNATAP -0.21 1.0E-5 NA
128 hsa-miR-181a-5p ADCY9 0.25 0.05519 -0.11 0.30518 miRNATAP -0.16 9.0E-5 NA
129 hsa-miR-181b-5p ADCY9 0.49 0.00105 -0.11 0.30518 miRNATAP -0.14 7.0E-5 24269684 miR 181b promotes cell proliferation and reduces apoptosis by repressing the expression of adenylyl cyclase 9 AC9 in cervical cancer cells; Phenotypic experiments indicated that miR-181b and AC9 exerted opposite effects on cell proliferation and apoptosis
130 hsa-miR-19b-3p ADCY9 0.6 0.00017 -0.11 0.30518 miRNATAP -0.1 0.00173 NA
131 hsa-miR-132-3p ADH1A 0.32 0.00272 -2.69 0 miRNAWalker2 validate -1.27 0 NA
132 hsa-miR-181a-5p ADM 0.25 0.05519 -1.26 0 MirTarget; miRNATAP -0.18 0.01203 NA
133 hsa-miR-181b-5p ADM 0.49 0.00105 -1.26 0 MirTarget; miRNATAP -0.18 0.00297 NA
134 hsa-miR-148a-3p ADM2 -0.75 0 1.72 0 mirMAP -0.43 0 NA
135 hsa-miR-29c-3p ADM2 -1.44 0 1.72 0 mirMAP -0.46 0 NA
136 hsa-miR-505-5p ADM2 -0.77 1.0E-5 1.72 0 mirMAP -0.33 0 NA
137 hsa-miR-34a-5p ADNP 1.04 0 0.17 0.10335 miRNAWalker2 validate -0.11 0.00156 NA
138 hsa-miR-34a-5p ADO 1.04 0 -0.24 0.00024 miRNAWalker2 validate; MirTarget -0.11 0 NA
139 hsa-miR-148a-3p ADPRH -0.75 0 -0.13 0.2674 MirTarget -0.25 0 NA
140 hsa-miR-455-5p ADPRH -0.27 0.05813 -0.13 0.2674 miRanda -0.21 0 NA
141 hsa-miR-30c-5p ADRA1D -0.43 0.00016 1.07 0.00499 MirTarget; miRNATAP -0.49 0.00285 NA
142 hsa-miR-30e-5p ADRA1D -0.63 0 1.07 0.00499 MirTarget -1.11 0 NA
143 hsa-miR-20a-5p ADRA2A 0.85 0 -0.76 0.02558 miRNATAP -0.4 2.0E-5 NA
144 hsa-miR-30e-5p ADRA2A -0.63 0 -0.76 0.02558 MirTarget -0.53 0.00123 NA
145 hsa-miR-192-3p AFAP1 -0.64 0.00027 0.33 0.05949 mirMAP -0.47 0 NA
146 hsa-miR-192-5p AFAP1 -0.5 0.00345 0.33 0.05949 mirMAP -0.49 0 NA
147 hsa-miR-192-5p AFAP1L1 -0.5 0.00345 0.54 1.0E-5 miRNAWalker2 validate -0.18 0 NA
148 hsa-miR-146b-5p AFAP1L2 0.42 0.04574 -0.55 0.00077 miRanda; miRNATAP -0.13 0.00063 NA
149 hsa-miR-34a-5p AFAP1L2 1.04 0 -0.55 0.00077 miRNAWalker2 validate -0.26 0 NA
150 hsa-miR-132-3p AFF1 0.32 0.00272 -0.71 0 mirMAP -0.2 0.0001 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 CELL DEVELOPMENT 451 1426 2.528e-35 1.176e-31
2 INTRACELLULAR SIGNAL TRANSDUCTION 481 1572 9.777e-34 1.35e-30
3 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 504 1672 1.414e-33 1.35e-30
4 NEUROGENESIS 440 1402 1.451e-33 1.35e-30
5 TISSUE DEVELOPMENT 468 1518 1.145e-33 1.35e-30
6 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 336 1021 9.952e-30 7.718e-27
7 REGULATION OF CELL DIFFERENTIATION 449 1492 1.287e-29 8.555e-27
8 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 559 1977 3.295e-29 1.917e-26
9 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 481 1656 7.886e-28 3.784e-25
10 CARDIOVASCULAR SYSTEM DEVELOPMENT 272 788 9.758e-28 3.784e-25
11 CIRCULATORY SYSTEM DEVELOPMENT 272 788 9.758e-28 3.784e-25
12 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 510 1784 9.284e-28 3.784e-25
13 POSITIVE REGULATION OF MOLECULAR FUNCTION 506 1791 3.08e-26 1.024e-23
14 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 387 1275 2.881e-26 1.024e-23
15 TISSUE MORPHOGENESIS 201 533 4.544e-26 1.41e-23
16 MORPHOGENESIS OF AN EPITHELIUM 161 400 1.495e-24 4.347e-22
17 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 191 513 4.729e-24 1.294e-21
18 CELLULAR COMPONENT MORPHOGENESIS 289 900 9.625e-24 2.392e-21
19 REGULATION OF CELLULAR COMPONENT MOVEMENT 257 771 9.769e-24 2.392e-21
20 PROTEIN PHOSPHORYLATION 299 944 1.706e-23 3.969e-21
21 POSITIVE REGULATION OF GENE EXPRESSION 482 1733 2.283e-23 5.058e-21
22 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 498 1805 2.454e-23 5.19e-21
23 ORGAN MORPHOGENESIS 273 841 3.099e-23 6.269e-21
24 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 393 1360 3.125e-22 6.058e-20
25 NEURON DIFFERENTIATION 277 874 7.436e-22 1.384e-19
26 PHOSPHORYLATION 361 1228 8.064e-22 1.443e-19
27 LOCOMOTION 334 1114 1.003e-21 1.729e-19
28 NEGATIVE REGULATION OF CELL COMMUNICATION 350 1192 4.519e-21 7.51e-19
29 TUBE DEVELOPMENT 194 552 4.901e-21 7.863e-19
30 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 294 957 6.893e-21 1.02e-18
31 POSITIVE REGULATION OF CATALYTIC ACTIVITY 424 1518 6.656e-21 1.02e-18
32 HEART DEVELOPMENT 171 466 7.016e-21 1.02e-18
33 EPITHELIUM DEVELOPMENT 291 945 7.559e-21 1.066e-18
34 NEGATIVE REGULATION OF GENE EXPRESSION 417 1493 1.482e-20 2.029e-18
35 REGULATION OF CELL DEVELOPMENT 262 836 5.631e-20 7.486e-18
36 POSITIVE REGULATION OF CELL COMMUNICATION 423 1532 7.431e-20 9.605e-18
37 REGULATION OF CELL DEATH 409 1472 1.001e-19 1.259e-17
38 CELL PROJECTION ORGANIZATION 276 902 2.175e-19 2.663e-17
39 REGULATION OF NEURON DIFFERENTIATION 190 554 2.691e-19 3.21e-17
40 TUBE MORPHOGENESIS 128 323 4.206e-19 4.893e-17
41 EMBRYO DEVELOPMENT 273 894 4.691e-19 5.323e-17
42 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 299 1004 4.813e-19 5.333e-17
43 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 331 1142 5.323e-19 5.74e-17
44 REGULATION OF PROTEIN MODIFICATION PROCESS 459 1710 5.428e-19 5.74e-17
45 REGULATION OF CELL PROLIFERATION 411 1496 6.959e-19 7.195e-17
46 REGULATION OF PHOSPHORUS METABOLIC PROCESS 438 1618 7.7e-19 7.788e-17
47 REGULATION OF CELL MORPHOGENESIS 188 552 9.718e-19 9.621e-17
48 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 409 1492 1.296e-18 1.256e-16
49 NEURON DEVELOPMENT 221 687 1.861e-18 1.768e-16
50 NEURON PROJECTION DEVELOPMENT 185 545 2.748e-18 2.557e-16
51 REGULATION OF CELL PROJECTION ORGANIZATION 188 558 3.544e-18 3.233e-16
52 POSITIVE REGULATION OF RESPONSE TO STIMULUS 503 1929 4.088e-18 3.59e-16
53 VASCULATURE DEVELOPMENT 165 469 4.089e-18 3.59e-16
54 SKELETAL SYSTEM DEVELOPMENT 161 455 5.627e-18 4.849e-16
55 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 329 1152 7.74e-18 6.548e-16
56 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 232 740 8.134e-18 6.759e-16
57 NEURON PROJECTION MORPHOGENESIS 146 402 1.501e-17 1.204e-15
58 REGULATION OF CELL ADHESION 204 629 1.5e-17 1.204e-15
59 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 233 750 2.294e-17 1.809e-15
60 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 408 1517 4.685e-17 3.633e-15
61 HEAD DEVELOPMENT 222 709 5.046e-17 3.849e-15
62 CELL MOTILITY 252 835 5.856e-17 4.325e-15
63 LOCALIZATION OF CELL 252 835 5.856e-17 4.325e-15
64 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 480 1848 5.989e-17 4.354e-15
65 RESPONSE TO OXYGEN CONTAINING COMPOUND 377 1381 7.058e-17 5.053e-15
66 CENTRAL NERVOUS SYSTEM DEVELOPMENT 260 872 9.689e-17 6.83e-15
67 REGULATION OF KINASE ACTIVITY 237 776 1.131e-16 7.855e-15
68 EMBRYONIC MORPHOGENESIS 179 539 1.157e-16 7.919e-15
69 REGULATION OF CELL CYCLE 277 949 1.887e-16 1.272e-14
70 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 134 368 2.543e-16 1.69e-14
71 REGULATION OF NEURON PROJECTION DEVELOPMENT 144 408 4.175e-16 2.736e-14
72 RESPONSE TO ENDOGENOUS STIMULUS 389 1450 4.274e-16 2.762e-14
73 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 318 1135 5.422e-16 3.456e-14
74 MESENCHYMAL CELL DIFFERENTIATION 66 134 6.14e-16 3.861e-14
75 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 376 1395 6.57e-16 4.076e-14
76 POSITIVE REGULATION OF LOCOMOTION 146 420 1.134e-15 6.943e-14
77 DEVELOPMENTAL GROWTH 123 333 1.252e-15 7.566e-14
78 REGULATION OF TRANSPORT 464 1804 1.363e-15 8.132e-14
79 CELL PART MORPHOGENESIS 199 633 1.422e-15 8.376e-14
80 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 150 437 1.578e-15 9.177e-14
81 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 287 1008 1.786e-15 1.026e-13
82 REGULATION OF TRANSFERASE ACTIVITY 272 946 2.792e-15 1.584e-13
83 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 123 337 3.52e-15 1.974e-13
84 GROWTH 142 410 3.95e-15 2.188e-13
85 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 292 1036 4.121e-15 2.23e-13
86 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 292 1036 4.121e-15 2.23e-13
87 REGULATION OF GTPASE ACTIVITY 207 673 4.747e-15 2.539e-13
88 MUSCLE STRUCTURE DEVELOPMENT 147 432 6.9e-15 3.648e-13
89 NEGATIVE REGULATION OF CELL DEATH 253 872 8.92e-15 4.664e-13
90 CYTOSKELETON ORGANIZATION 245 838 9.441e-15 4.881e-13
91 STEM CELL DIFFERENTIATION 81 190 1.156e-14 5.913e-13
92 POSITIVE REGULATION OF CELL DIFFERENTIATION 241 823 1.298e-14 6.567e-13
93 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 235 799 1.667e-14 8.342e-13
94 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 209 689 1.695e-14 8.391e-13
95 WNT SIGNALING PATHWAY 125 351 1.737e-14 8.508e-13
96 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 235 801 2.251e-14 1.091e-12
97 BLOOD VESSEL MORPHOGENESIS 128 364 2.497e-14 1.198e-12
98 POSITIVE REGULATION OF CELL PROLIFERATION 237 814 4.334e-14 2.058e-12
99 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 175 554 4.741e-14 2.228e-12
100 PROTEIN LOCALIZATION 455 1805 9.379e-14 4.364e-12
101 MESENCHYME DEVELOPMENT 79 190 1.245e-13 5.737e-12
102 ACTIN FILAMENT BASED PROCESS 148 450 1.29e-13 5.885e-12
103 REGULATION OF CELLULAR COMPONENT SIZE 119 337 1.46e-13 6.595e-12
104 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 103 278 2.064e-13 9.237e-12
105 BIOLOGICAL ADHESION 284 1032 2.359e-13 1.045e-11
106 CELL PROLIFERATION 201 672 2.463e-13 1.081e-11
107 POSITIVE REGULATION OF HYDROLASE ACTIVITY 255 905 2.635e-13 1.146e-11
108 REGULATION OF HYDROLASE ACTIVITY 349 1327 3.12e-13 1.344e-11
109 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 122 352 3.244e-13 1.385e-11
110 UROGENITAL SYSTEM DEVELOPMENT 108 299 3.69e-13 1.561e-11
111 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 89 229 3.908e-13 1.638e-11
112 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 272 983 3.985e-13 1.655e-11
113 CELL CYCLE 346 1316 4.17e-13 1.717e-11
114 REGULATION OF ORGANELLE ORGANIZATION 315 1178 5.579e-13 2.277e-11
115 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 247 876 5.875e-13 2.377e-11
116 REGULATION OF ANATOMICAL STRUCTURE SIZE 151 472 8.774e-13 3.52e-11
117 POSITIVE REGULATION OF KINASE ACTIVITY 153 482 1.238e-12 4.923e-11
118 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 150 470 1.289e-12 5.081e-11
119 MORPHOGENESIS OF A BRANCHING STRUCTURE 70 167 1.92e-12 7.509e-11
120 NEGATIVE REGULATION OF CELL PROLIFERATION 191 643 1.966e-12 7.622e-11
121 CELL DEATH 272 1001 3.647e-12 1.402e-10
122 POSITIVE REGULATION OF CELL DEATH 181 605 3.849e-12 1.468e-10
123 POSITIVE REGULATION OF CELL DEVELOPMENT 149 472 3.922e-12 1.484e-10
124 POSITIVE REGULATION OF NEURON DIFFERENTIATION 107 306 4.935e-12 1.852e-10
125 REGULATION OF CELLULAR LOCALIZATION 332 1277 5.925e-12 2.206e-10
126 REGULATION OF DEVELOPMENTAL GROWTH 102 289 8.23e-12 3.039e-10
127 POSITIVE REGULATION OF CELL CYCLE 113 332 9.066e-12 3.322e-10
128 REGULATION OF CELL SIZE 70 172 1.013e-11 3.684e-10
129 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 182 616 1.093e-11 3.944e-10
130 MUSCLE TISSUE DEVELOPMENT 98 275 1.113e-11 3.982e-10
131 HEART MORPHOGENESIS 81 212 1.23e-11 4.371e-10
132 NEURON PROJECTION GUIDANCE 79 205 1.33e-11 4.687e-10
133 SENSORY ORGAN DEVELOPMENT 152 493 1.783e-11 6.237e-10
134 GLAND MORPHOGENESIS 47 97 1.92e-11 6.668e-10
135 REGULATION OF EPITHELIAL CELL PROLIFERATION 100 285 1.944e-11 6.702e-10
136 RESPONSE TO EXTERNAL STIMULUS 445 1821 2.658e-11 9.093e-10
137 RESPONSE TO ABIOTIC STIMULUS 273 1024 3.118e-11 1.059e-09
138 EMBRYONIC ORGAN DEVELOPMENT 130 406 3.183e-11 1.073e-09
139 TAXIS 144 464 3.604e-11 1.206e-09
140 CONNECTIVE TISSUE DEVELOPMENT 75 194 3.634e-11 1.208e-09
141 REGULATION OF CYTOSKELETON ORGANIZATION 153 502 4.007e-11 1.322e-09
142 EXTRACELLULAR STRUCTURE ORGANIZATION 104 304 4.311e-11 1.413e-09
143 RESPONSE TO LIPID 242 888 4.421e-11 1.439e-09
144 REGULATION OF BINDING 98 283 7.204e-11 2.328e-09
145 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 103 303 8.12e-11 2.606e-09
146 GLAND DEVELOPMENT 126 395 8.436e-11 2.689e-09
147 CELL CYCLE PROCESS 283 1081 1.111e-10 3.517e-09
148 RESPONSE TO GROWTH FACTOR 145 475 1.148e-10 3.608e-09
149 OSSIFICATION 89 251 1.313e-10 4.1e-09
150 RESPONSE TO HORMONE 241 893 1.356e-10 4.205e-09
151 NEGATIVE REGULATION OF CELL DIFFERENTIATION 176 609 1.705e-10 5.253e-09
152 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 77 207 1.751e-10 5.347e-09
153 MUSCLE CELL DIFFERENTIATION 85 237 1.758e-10 5.347e-09
154 REGULATION OF CELLULAR COMPONENT BIOGENESIS 212 767 1.941e-10 5.865e-09
155 REGULATION OF ACTIN FILAMENT BASED PROCESS 104 312 2.367e-10 7.105e-09
156 REGULATION OF GROWTH 181 633 2.393e-10 7.139e-09
157 ANGIOGENESIS 99 293 2.748e-10 8.145e-09
158 FOREBRAIN DEVELOPMENT 115 357 2.887e-10 8.503e-09
159 TELENCEPHALON DEVELOPMENT 82 228 3.136e-10 9.178e-09
160 REGULATION OF PROTEIN LOCALIZATION 252 950 3.175e-10 9.233e-09
161 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 64 162 3.39e-10 9.799e-09
162 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 47 104 3.884e-10 1.116e-08
163 RESPONSE TO ORGANIC CYCLIC COMPOUND 244 917 4.49e-10 1.282e-08
164 REGULATION OF AXON GUIDANCE 25 39 4.606e-10 1.307e-08
165 KIDNEY EPITHELIUM DEVELOPMENT 53 125 5.456e-10 1.539e-08
166 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 148 498 6.03e-10 1.69e-08
167 AMEBOIDAL TYPE CELL MIGRATION 61 154 7.707e-10 2.147e-08
168 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 82 232 8.243e-10 2.283e-08
169 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 69 184 1.02e-09 2.808e-08
170 ESTABLISHMENT OF LOCALIZATION IN CELL 405 1676 1.088e-09 2.979e-08
171 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 54 131 1.304e-09 3.548e-08
172 NEURAL CREST CELL DIFFERENTIATION 37 75 1.378e-09 3.727e-08
173 RESPONSE TO ALCOHOL 114 362 1.537e-09 4.135e-08
174 REGULATION OF CELL GROWTH 121 391 1.595e-09 4.266e-08
175 RESPONSE TO INORGANIC SUBSTANCE 142 479 1.612e-09 4.286e-08
176 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 132 437 1.65e-09 4.363e-08
177 REPRODUCTIVE SYSTEM DEVELOPMENT 125 408 1.712e-09 4.501e-08
178 EPITHELIAL CELL DEVELOPMENT 69 186 1.741e-09 4.551e-08
179 PROTEIN DEPHOSPHORYLATION 70 190 1.874e-09 4.871e-08
180 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 189 684 1.967e-09 5.086e-08
181 NEGATIVE REGULATION OF PHOSPHORYLATION 128 422 2.189e-09 5.627e-08
182 NEGATIVE REGULATION OF CELL ADHESION 78 223 3.63e-09 9.281e-08
183 DEPHOSPHORYLATION 94 286 3.845e-09 9.777e-08
184 ORGAN GROWTH 34 68 4.075e-09 1.031e-07
185 VESICLE MEDIATED TRANSPORT 309 1239 4.419e-09 1.111e-07
186 CELLULAR RESPONSE TO STRESS 378 1565 4.445e-09 1.112e-07
187 RESPONSE TO OXYGEN LEVELS 100 311 4.584e-09 1.14e-07
188 CELLULAR RESPONSE TO LIPID 135 457 5.189e-09 1.284e-07
189 CELLULAR RESPONSE TO HORMONE STIMULUS 157 552 5.613e-09 1.382e-07
190 REGULATION OF EXTENT OF CELL GROWTH 44 101 5.687e-09 1.393e-07
191 RESPONSE TO NITROGEN COMPOUND 226 859 5.793e-09 1.411e-07
192 POSITIVE REGULATION OF CATABOLIC PROCESS 120 395 6.241e-09 1.513e-07
193 ESTABLISHMENT OF PROTEIN LOCALIZATION 347 1423 6.816e-09 1.643e-07
194 CARTILAGE DEVELOPMENT 57 147 6.893e-09 1.653e-07
195 REGULATION OF CELL CYCLE PROCESS 158 558 7.021e-09 1.675e-07
196 REGULATION OF MAPK CASCADE 181 660 8.001e-09 1.89e-07
197 REGULATION OF SYSTEM PROCESS 146 507 7.99e-09 1.89e-07
198 CELL DIVISION 135 460 8.137e-09 1.912e-07
199 NEGATIVE REGULATION OF MOLECULAR FUNCTION 273 1079 8.922e-09 2.086e-07
200 POST EMBRYONIC DEVELOPMENT 40 89 9.374e-09 2.181e-07
201 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 53 134 1.034e-08 2.394e-07
202 MITOTIC CELL CYCLE 204 766 1.169e-08 2.692e-07
203 NEURAL TUBE DEVELOPMENT 57 149 1.224e-08 2.805e-07
204 REGULATION OF CATABOLIC PROCESS 196 731 1.301e-08 2.968e-07
205 PALLIUM DEVELOPMENT 58 153 1.349e-08 3.061e-07
206 REGULATION OF AXONOGENESIS 62 168 1.433e-08 3.236e-07
207 EYE DEVELOPMENT 102 326 1.601e-08 3.6e-07
208 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 38 84 1.754e-08 3.923e-07
209 REGULATION OF CELLULAR PROTEIN LOCALIZATION 155 552 1.794e-08 3.993e-07
210 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 273 1087 1.868e-08 4.14e-07
211 SEMAPHORIN PLEXIN SIGNALING PATHWAY 22 36 1.879e-08 4.144e-07
212 TUBE FORMATION 51 129 1.981e-08 4.347e-07
213 EPITHELIAL TO MESENCHYMAL TRANSITION 29 56 2.028e-08 4.43e-07
214 POSITIVE REGULATION OF TRANSPORT 240 936 2.202e-08 4.768e-07
215 CELLULAR MACROMOLECULE LOCALIZATION 304 1234 2.203e-08 4.768e-07
216 EMBRYONIC ORGAN MORPHOGENESIS 90 279 2.243e-08 4.832e-07
217 NEGATIVE REGULATION OF LOCOMOTION 86 263 2.273e-08 4.874e-07
218 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 55 144 2.336e-08 4.964e-07
219 GLYCOPROTEIN METABOLIC PROCESS 108 353 2.337e-08 4.964e-07
220 PEPTIDYL AMINO ACID MODIFICATION 219 841 2.48e-08 5.245e-07
221 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 75 220 2.518e-08 5.301e-07
222 CANONICAL WNT SIGNALING PATHWAY 41 95 2.58e-08 5.407e-07
223 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 120 404 2.596e-08 5.417e-07
224 REGULATION OF OSSIFICATION 64 178 2.698e-08 5.605e-07
225 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 159 573 2.801e-08 5.793e-07
226 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 42 99 3.201e-08 6.561e-07
227 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 42 99 3.201e-08 6.561e-07
228 REGULATION OF DENDRITE DEVELOPMENT 48 120 3.312e-08 6.759e-07
229 NEGATIVE REGULATION OF CHEMOTAXIS 27 51 3.376e-08 6.86e-07
230 REGULATION OF WNT SIGNALING PATHWAY 97 310 3.557e-08 7.195e-07
231 REGULATION OF RESPONSE TO STRESS 352 1468 3.658e-08 7.369e-07
232 ORGANELLE LOCALIZATION 122 415 3.799e-08 7.62e-07
233 CELL GROWTH 52 135 4.024e-08 8.036e-07
234 REGULATION OF INTRACELLULAR TRANSPORT 169 621 4.453e-08 8.854e-07
235 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 48 121 4.51e-08 8.929e-07
236 AMINOGLYCAN BIOSYNTHETIC PROCESS 44 107 4.653e-08 9.174e-07
237 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 236 926 4.983e-08 9.777e-07
238 POSITIVE REGULATION OF CELL CYCLE PROCESS 81 247 5.001e-08 9.777e-07
239 STRIATED MUSCLE CELL DIFFERENTIATION 62 173 5.075e-08 9.84e-07
240 REGULATION OF CELL SUBSTRATE ADHESION 62 173 5.075e-08 9.84e-07
241 NEGATIVE REGULATION OF AXON GUIDANCE 18 27 5.354e-08 1.034e-06
242 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 133 465 5.699e-08 1.096e-06
243 REGULATION OF EPITHELIAL CELL MIGRATION 60 166 5.829e-08 1.116e-06
244 REGULATION OF CELL CELL ADHESION 113 380 6.141e-08 1.171e-06
245 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 91 289 6.725e-08 1.277e-06
246 PROTEIN UBIQUITINATION 170 629 6.759e-08 1.278e-06
247 COLLAGEN FIBRIL ORGANIZATION 22 38 7.486e-08 1.405e-06
248 NEGATIVE REGULATION OF AXON EXTENSION 22 38 7.486e-08 1.405e-06
249 REGULATION OF OSTEOBLAST DIFFERENTIATION 45 112 7.519e-08 1.405e-06
250 SMOOTH MUSCLE TISSUE DEVELOPMENT 14 18 7.925e-08 1.475e-06
251 REGULATION OF CYTOPLASMIC TRANSPORT 136 481 8.558e-08 1.58e-06
252 RESPONSE TO MECHANICAL STIMULUS 71 210 8.531e-08 1.58e-06
253 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 42 102 8.915e-08 1.633e-06
254 RESPONSE TO HYDROGEN PEROXIDE 44 109 8.892e-08 1.633e-06
255 NEGATIVE REGULATION OF CELL DEVELOPMENT 94 303 9.036e-08 1.643e-06
256 REGULATION OF ORGAN MORPHOGENESIS 79 242 9.039e-08 1.643e-06
257 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 52 138 9.334e-08 1.683e-06
258 PALATE DEVELOPMENT 37 85 9.301e-08 1.683e-06
259 PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 223 873 9.708e-08 1.744e-06
260 ENDOMEMBRANE SYSTEM ORGANIZATION 132 465 1.03e-07 1.843e-06
261 REGULATION OF CHEMOTAXIS 63 180 1.084e-07 1.932e-06
262 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 163 602 1.106e-07 1.964e-06
263 RESPONSE TO DRUG 124 431 1.116e-07 1.974e-06
264 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 46 117 1.171e-07 2.063e-06
265 POSITIVE REGULATION OF CELL ADHESION 111 376 1.215e-07 2.132e-06
266 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 42 103 1.237e-07 2.164e-06
267 CARBOHYDRATE DERIVATIVE BIOSYNTHETIC PROCESS 161 595 1.383e-07 2.411e-06
268 NEGATIVE CHEMOTAXIS 22 39 1.416e-07 2.459e-06
269 SINGLE ORGANISM CELL ADHESION 130 459 1.478e-07 2.547e-06
270 NEGATIVE REGULATION OF CELL CYCLE 124 433 1.475e-07 2.547e-06
271 SPROUTING ANGIOGENESIS 24 45 1.621e-07 2.784e-06
272 REGULATION OF MAP KINASE ACTIVITY 97 319 1.642e-07 2.81e-06
273 ENDOTHELIUM DEVELOPMENT 38 90 1.657e-07 2.824e-06
274 EPITHELIAL CELL DIFFERENTIATION 138 495 1.704e-07 2.894e-06
275 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 53 144 1.723e-07 2.915e-06
276 CARBOHYDRATE DERIVATIVE METABOLIC PROCESS 259 1047 1.772e-07 2.987e-06
277 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 45 115 1.882e-07 3.161e-06
278 NEURAL TUBE FORMATION 39 94 2.002e-07 3.35e-06
279 REGULATION OF BMP SIGNALING PATHWAY 34 77 2.009e-07 3.351e-06
280 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 148 541 2.167e-07 3.588e-06
281 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 148 541 2.167e-07 3.588e-06
282 RESPONSE TO STEROID HORMONE 138 497 2.199e-07 3.628e-06
283 IMMUNE SYSTEM DEVELOPMENT 157 582 2.43e-07 3.996e-06
284 CELLULAR RESPONSE TO EXTERNAL STIMULUS 83 264 2.681e-07 4.389e-06
285 REGULATION OF CELLULAR RESPONSE TO STRESS 181 691 2.688e-07 4.389e-06
286 REGULATION OF MITOTIC CELL CYCLE 131 468 2.727e-07 4.436e-06
287 RESPONSE TO OXIDATIVE STRESS 104 352 2.874e-07 4.659e-06
288 MUSCLE ORGAN DEVELOPMENT 86 277 3.021e-07 4.856e-06
289 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 188 724 3.027e-07 4.856e-06
290 CARDIAC EPITHELIAL TO MESENCHYMAL TRANSITION 16 24 3.018e-07 4.856e-06
291 RAS PROTEIN SIGNAL TRANSDUCTION 52 143 3.484e-07 5.571e-06
292 REGULATION OF HOMOTYPIC CELL CELL ADHESION 93 307 3.535e-07 5.614e-06
293 SKELETAL SYSTEM MORPHOGENESIS 67 201 3.533e-07 5.614e-06
294 REGULATION OF VASCULATURE DEVELOPMENT 75 233 3.548e-07 5.616e-06
295 AMINOGLYCAN METABOLIC PROCESS 58 166 3.637e-07 5.736e-06
296 ENDOTHELIAL CELL DIFFERENTIATION 32 72 3.798e-07 5.97e-06
297 CHEMICAL HOMEOSTASIS 220 874 3.928e-07 6.154e-06
298 CARDIAC MUSCLE TISSUE DEVELOPMENT 51 140 4.221e-07 6.568e-06
299 SINGLE ORGANISM CELLULAR LOCALIZATION 225 898 4.209e-07 6.568e-06
300 CELL JUNCTION ASSEMBLY 48 129 4.436e-07 6.88e-06
301 CARDIAC CHAMBER DEVELOPMENT 52 144 4.48e-07 6.925e-06
302 PROTEIN CATABOLIC PROCESS 155 579 4.796e-07 7.389e-06
303 BONE DEVELOPMENT 55 156 5.179e-07 7.921e-06
304 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 55 156 5.179e-07 7.921e-06
305 RESPONSE TO REACTIVE OXYGEN SPECIES 64 191 5.192e-07 7.921e-06
306 OSTEOBLAST DIFFERENTIATION 47 126 5.354e-07 8.124e-06
307 REGULATION OF CELL MATRIX ADHESION 37 90 5.36e-07 8.124e-06
308 NEPHRON DEVELOPMENT 44 115 5.383e-07 8.132e-06
309 ESTABLISHMENT OR MAINTENANCE OF CELL POLARITY 51 141 5.432e-07 8.18e-06
310 AGING 82 264 5.525e-07 8.292e-06
311 RESPONSE TO WOUNDING 151 563 5.962e-07 8.92e-06
312 CEREBRAL CORTEX DEVELOPMENT 41 105 6.923e-07 1.032e-05
313 DEVELOPMENTAL CELL GROWTH 33 77 7.007e-07 1.042e-05
314 APPENDAGE DEVELOPMENT 58 169 7.175e-07 1.06e-05
315 LIMB DEVELOPMENT 58 169 7.175e-07 1.06e-05
316 RESPONSE TO ESTRADIOL 52 146 7.321e-07 1.078e-05
317 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 65 197 7.896e-07 1.159e-05
318 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 162 616 8.728e-07 1.277e-05
319 CELLULAR RESPONSE TO OXYGEN LEVELS 51 143 8.893e-07 1.297e-05
320 NEGATIVE REGULATION OF CELL GROWTH 58 170 8.944e-07 1.3e-05
321 CARDIAC SEPTUM DEVELOPMENT 35 85 1.03e-06 1.489e-05
322 NEURON MIGRATION 42 110 1.03e-06 1.489e-05
323 POSITIVE REGULATION OF MAPK CASCADE 129 470 1.061e-06 1.528e-05
324 NON CANONICAL WNT SIGNALING PATHWAY 50 140 1.08e-06 1.551e-05
325 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 63 191 1.173e-06 1.679e-05
326 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 24 49 1.255e-06 1.791e-05
327 NEGATIVE REGULATION OF GROWTH 74 236 1.3e-06 1.85e-05
328 RESPONSE TO EXTRACELLULAR STIMULUS 122 441 1.337e-06 1.896e-05
329 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 46 126 1.421e-06 2.009e-05
330 REGULATION OF BLOOD CIRCULATION 88 295 1.476e-06 2.081e-05
331 MEMBRANE ORGANIZATION 222 899 1.566e-06 2.201e-05
332 REGULATION OF HEART CONTRACTION 70 221 1.657e-06 2.322e-05
333 CELLULAR RESPONSE TO NITROGEN COMPOUND 136 505 1.684e-06 2.353e-05
334 CELL ACTIVATION 150 568 1.707e-06 2.378e-05
335 LIPID TRANSLOCATION 14 21 1.712e-06 2.378e-05
336 CELL JUNCTION ORGANIZATION 61 185 1.742e-06 2.412e-05
337 STEM CELL DIVISION 17 29 1.826e-06 2.521e-05
338 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 25 53 1.836e-06 2.528e-05
339 POSITIVE REGULATION OF GROWTH 74 238 1.848e-06 2.537e-05
340 PATTERN SPECIFICATION PROCESS 116 418 2.043e-06 2.796e-05
341 NEGATIVE REGULATION OF TRANSPORT 125 458 2.117e-06 2.889e-05
342 GLIOGENESIS 58 175 2.576e-06 3.496e-05
343 REGULATION OF MUSCLE SYSTEM PROCESS 63 195 2.577e-06 3.496e-05
344 CARDIAC MUSCLE CELL DIFFERENTIATION 31 74 2.714e-06 3.672e-05
345 PEPTIDYL SERINE MODIFICATION 51 148 2.856e-06 3.852e-05
346 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 82 274 2.881e-06 3.875e-05
347 IMMUNE SYSTEM PROCESS 444 1984 3.033e-06 4.066e-05
348 WOUND HEALING 127 470 3.058e-06 4.088e-05
349 NEURAL CREST CELL MIGRATION 24 51 3.101e-06 4.134e-05
350 REGULATION OF PROTEIN BINDING 56 168 3.116e-06 4.143e-05
351 PROTEIN AUTOPHOSPHORYLATION 62 192 3.14e-06 4.162e-05
352 CELLULAR RESPONSE TO OXIDATIVE STRESS 60 184 3.162e-06 4.18e-05
353 RENAL TUBULE DEVELOPMENT 32 78 3.241e-06 4.272e-05
354 CELLULAR RESPONSE TO HYDROGEN PEROXIDE 27 61 3.345e-06 4.397e-05
355 EPITHELIAL CELL PROLIFERATION 35 89 3.646e-06 4.779e-05
356 SOMATIC STEM CELL DIVISION 14 22 3.902e-06 5.1e-05
357 CARDIAC CHAMBER MORPHOGENESIS 39 104 4.132e-06 5.355e-05
358 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 112 406 4.119e-06 5.355e-05
359 CELLULAR RESPONSE TO REACTIVE OXYGEN SPECIES 39 104 4.132e-06 5.355e-05
360 NEGATIVE REGULATION OF AXONOGENESIS 28 65 4.245e-06 5.487e-05
361 PROTEIN POLYUBIQUITINATION 74 243 4.312e-06 5.557e-05
362 MUCOPOLYSACCHARIDE METABOLIC PROCESS 40 108 4.472e-06 5.748e-05
363 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 61 190 4.627e-06 5.931e-05
364 REGULATION OF HOMEOSTATIC PROCESS 121 447 4.724e-06 6.039e-05
365 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 106 381 4.894e-06 6.239e-05
366 MESONEPHROS DEVELOPMENT 35 90 4.91e-06 6.242e-05
367 CYTOSKELETON DEPENDENT INTRACELLULAR TRANSPORT 42 116 5.101e-06 6.468e-05
368 ORGAN REGENERATION 33 83 5.178e-06 6.53e-05
369 PROTEOGLYCAN METABOLIC PROCESS 33 83 5.178e-06 6.53e-05
370 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 72 236 5.371e-06 6.755e-05
371 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 63 199 5.45e-06 6.836e-05
372 EAR DEVELOPMENT 62 195 5.521e-06 6.906e-05
373 RESPONSE TO NUTRIENT 61 191 5.584e-06 6.965e-05
374 REGULATION OF VESICLE MEDIATED TRANSPORT 124 462 5.691e-06 7.062e-05
375 REGULATION OF PROTEIN IMPORT 59 183 5.678e-06 7.062e-05
376 MUSCLE CELL DEVELOPMENT 45 128 5.889e-06 7.288e-05
377 NEGATIVE REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 28 66 6.077e-06 7.48e-05
378 NEGATIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 28 66 6.077e-06 7.48e-05
379 MORPHOGENESIS OF AN EPITHELIAL SHEET 21 43 6.119e-06 7.493e-05
380 REGULATION OF POLYSACCHARIDE METABOLIC PROCESS 21 43 6.119e-06 7.493e-05
381 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 78 262 6.153e-06 7.499e-05
382 CELLULAR RESPONSE TO MECHANICAL STIMULUS 32 80 6.157e-06 7.499e-05
383 REGULATION OF STEM CELL DIFFERENTIATION 41 113 6.191e-06 7.521e-05
384 REGULATION OF MEMBRANE LIPID DISTRIBUTION 19 37 6.631e-06 8.014e-05
385 HEART VALVE DEVELOPMENT 18 34 6.629e-06 8.014e-05
386 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 29 70 7.342e-06 8.851e-05
387 GOLGI VESICLE TRANSPORT 91 319 7.594e-06 9.13e-05
388 CATABOLIC PROCESS 398 1773 7.704e-06 9.239e-05
389 RESPIRATORY SYSTEM DEVELOPMENT 62 197 7.95e-06 9.509e-05
390 PHOSPHATIDYLINOSITOL METABOLIC PROCESS 61 193 8.072e-06 9.625e-05
391 STEM CELL PROLIFERATION 26 60 8.129e-06 9.625e-05
392 CHONDROCYTE DIFFERENTIATION 26 60 8.129e-06 9.625e-05
393 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 26 60 8.129e-06 9.625e-05
394 REGENERATION 53 161 8.505e-06 0.0001004
395 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 67 218 8.54e-06 0.0001006
396 REGULATION OF DENDRITE MORPHOGENESIS 30 74 8.655e-06 0.0001017
397 NEGATIVE REGULATION OF CELL CYCLE PROCESS 66 214 8.748e-06 0.0001024
398 SENSORY ORGAN MORPHOGENESIS 72 239 8.76e-06 0.0001024
399 REGULATION OF CELL ACTIVATION 128 484 8.916e-06 0.000104
400 RESPONSE TO PEPTIDE 110 404 9.477e-06 0.0001101
401 REGULATION OF TRANSPORTER ACTIVITY 62 198 9.506e-06 0.0001101
402 CHROMATIN MODIFICATION 140 539 9.51e-06 0.0001101
403 CARDIOCYTE DIFFERENTIATION 36 96 9.541e-06 0.0001102
404 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 49 146 1.014e-05 0.0001168
405 PEPTIDYL TYROSINE DEPHOSPHORYLATION 37 100 1.032e-05 0.0001185
406 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 101 365 1.039e-05 0.0001188
407 LUNG ALVEOLUS DEVELOPMENT 20 41 1.039e-05 0.0001188
408 NEUROBLAST PROLIFERATION 16 29 1.081e-05 0.0001232
409 NEPHRON EPITHELIUM DEVELOPMENT 35 93 1.152e-05 0.0001307
410 MULTICELLULAR ORGANISM METABOLIC PROCESS 35 93 1.152e-05 0.0001307
411 ACTIVATION OF PROTEIN KINASE ACTIVITY 81 279 1.163e-05 0.0001317
412 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 64 208 1.29e-05 0.0001456
413 NEGATIVE REGULATION OF KINASE ACTIVITY 74 250 1.311e-05 0.0001477
414 REGULATION OF BODY FLUID LEVELS 132 506 1.348e-05 0.0001515
415 DENDRITE DEVELOPMENT 31 79 1.354e-05 0.0001516
416 CHONDROCYTE DEVELOPMENT 13 21 1.356e-05 0.0001516
417 RESPONSE TO ACID CHEMICAL 90 319 1.366e-05 0.0001524
418 INOSITOL LIPID MEDIATED SIGNALING 43 124 1.389e-05 0.0001547
419 REGULATION OF NEURON APOPTOTIC PROCESS 60 192 1.406e-05 0.0001561
420 IN UTERO EMBRYONIC DEVELOPMENT 88 311 1.498e-05 0.0001656
421 ENDOCHONDRAL BONE MORPHOGENESIS 21 45 1.497e-05 0.0001656
422 RESPONSE TO BMP 35 94 1.511e-05 0.0001662
423 CELLULAR RESPONSE TO BMP STIMULUS 35 94 1.511e-05 0.0001662
424 RESPONSE TO METAL ION 93 333 1.54e-05 0.0001686
425 POSITIVE REGULATION OF CELL GROWTH 49 148 1.537e-05 0.0001686
426 POSITIVE REGULATION OF WNT SIGNALING PATHWAY 50 152 1.543e-05 0.0001686
427 CARDIAC VENTRICLE MORPHOGENESIS 26 62 1.659e-05 0.0001804
428 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 26 62 1.659e-05 0.0001804
429 RESPONSE TO ESTROGEN 66 218 1.704e-05 0.0001844
430 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 66 218 1.704e-05 0.0001844
431 GLYCEROLIPID METABOLIC PROCESS 98 356 1.756e-05 0.0001894
432 NEGATIVE REGULATION OF ORGANELLE ORGANIZATION 105 387 1.758e-05 0.0001894
433 REGULATION OF PHOSPHOLIPASE C ACTIVITY 19 39 1.767e-05 0.0001899
434 REGULATION OF CATENIN IMPORT INTO NUCLEUS 15 27 1.83e-05 0.0001962
435 REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 18 36 1.867e-05 0.0001997
436 NEGATIVE REGULATION OF MAPK CASCADE 48 145 1.876e-05 0.0002002
437 NEGATIVE REGULATION OF CELL MATRIX ADHESION 16 30 1.917e-05 0.0002037
438 POSITIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 16 30 1.917e-05 0.0002037
439 NEGATIVE REGULATION OF MAP KINASE ACTIVITY 29 73 1.93e-05 0.0002045
440 MACROMOLECULE CATABOLIC PROCESS 221 926 1.951e-05 0.0002064
441 REGULATION OF ENDOTHELIAL CELL MIGRATION 40 114 1.996e-05 0.0002096
442 NOTCH SIGNALING PATHWAY 40 114 1.996e-05 0.0002096
443 CARBOHYDRATE METABOLIC PROCESS 165 662 1.989e-05 0.0002096
444 CARDIAC SEPTUM MORPHOGENESIS 22 49 2.022e-05 0.0002114
445 POSITIVE REGULATION OF OSSIFICATION 32 84 2.019e-05 0.0002114
446 REGULATION OF PROTEIN CATABOLIC PROCESS 106 393 2.108e-05 0.0002199
447 PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 45 134 2.249e-05 0.0002336
448 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 53 166 2.245e-05 0.0002336
449 NEGATIVE REGULATION OF CELL CELL ADHESION 46 138 2.273e-05 0.0002356
450 CELL CYCLE ARREST 50 154 2.294e-05 0.0002365
451 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 50 154 2.294e-05 0.0002365
452 NEURAL PRECURSOR CELL PROLIFERATION 28 70 2.298e-05 0.0002365
453 CELL CELL ADHESION 153 608 2.327e-05 0.000239
454 CELLULAR RESPONSE TO ALCOHOL 40 115 2.518e-05 0.0002581
455 EPHRIN RECEPTOR SIGNALING PATHWAY 32 85 2.668e-05 0.0002728
456 MICROTUBULE BASED PROCESS 134 522 2.698e-05 0.0002753
457 RETINA DEVELOPMENT IN CAMERA TYPE EYE 44 131 2.745e-05 0.0002795
458 LYMPHOCYTE ACTIVATION 94 342 2.754e-05 0.0002798
459 REGULATION OF JNK CASCADE 51 159 2.763e-05 0.0002801
460 REGULATION OF SECRETION 172 699 2.874e-05 0.0002907
461 REGULATION OF DNA BINDING 34 93 3.098e-05 0.0003127
462 POSITIVE REGULATION OF CELL CELL ADHESION 71 243 3.11e-05 0.0003133
463 REGULATION OF CARBOHYDRATE METABOLIC PROCESS 54 172 3.194e-05 0.0003209
464 CELL SUBSTRATE ADHESION 52 164 3.293e-05 0.0003302
465 MICROTUBULE CYTOSKELETON ORGANIZATION 95 348 3.338e-05 0.000334
466 DEVELOPMENTAL MATURATION 59 193 3.4e-05 0.0003395
467 REGULATION OF GLUCOSE IMPORT IN RESPONSE TO INSULIN STIMULUS 11 17 3.565e-05 0.0003552
468 CELL FATE COMMITMENT 67 227 3.62e-05 0.0003599
469 VACUOLAR TRANSPORT 73 253 3.833e-05 0.0003803
470 MULTICELLULAR ORGANISMAL MACROMOLECULE METABOLIC PROCESS 30 79 3.887e-05 0.000384
471 BONE MORPHOGENESIS 30 79 3.887e-05 0.000384
472 MAMMARY GLAND DEVELOPMENT 40 117 3.955e-05 0.0003899
473 ANTERIOR POSTERIOR PATTERN SPECIFICATION 59 194 4.015e-05 0.0003941
474 CELL CYCLE CHECKPOINT 59 194 4.015e-05 0.0003941
475 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 44 133 4.164e-05 0.0004079
476 GLYCEROPHOSPHOLIPID METABOLIC PROCESS 83 297 4.19e-05 0.0004095
477 RESPONSE TO VITAMIN 35 98 4.211e-05 0.0004108
478 PROSTATE GLAND DEVELOPMENT 19 41 4.288e-05 0.0004174
479 RESPONSE TO KETONE 56 182 4.344e-05 0.000422
480 NEGATIVE REGULATION OF HOMOTYPIC CELL CELL ADHESION 36 102 4.402e-05 0.0004267
481 PLASMA MEMBRANE ORGANIZATION 61 203 4.448e-05 0.0004303
482 PROTEOGLYCAN BIOSYNTHETIC PROCESS 24 58 4.513e-05 0.0004357
483 ORGANOPHOSPHATE METABOLIC PROCESS 210 885 4.545e-05 0.0004378
484 CARDIAC VENTRICLE DEVELOPMENT 37 106 4.568e-05 0.0004382
485 REGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS 32 87 4.562e-05 0.0004382
486 POSITIVE REGULATION OF PROTEIN CATABOLIC PROCESS 75 263 4.653e-05 0.0004455
487 MULTICELLULAR ORGANISM GROWTH 29 76 4.686e-05 0.0004478
488 SUBSTRATE ADHESION DEPENDENT CELL SPREADING 18 38 4.727e-05 0.0004498
489 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 18 38 4.727e-05 0.0004498
490 REGULATION OF CELL DIVISION 77 272 4.871e-05 0.0004626
491 NEGATIVE REGULATION OF CELL ACTIVATION 50 158 4.888e-05 0.0004632
492 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 41 122 4.997e-05 0.0004717
493 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORT 21 48 4.992e-05 0.0004717
494 PERIPHERAL NERVOUS SYSTEM DEVELOPMENT 27 69 5.061e-05 0.0004757
495 POSITIVE REGULATION OF AXONOGENESIS 27 69 5.061e-05 0.0004757
496 REGULATION OF GLYCOGEN METABOLIC PROCESS 17 35 5.124e-05 0.0004807
497 LIPID PHOSPHORYLATION 35 99 5.365e-05 0.0005023
498 CELLULAR RESPONSE TO ACID CHEMICAL 54 175 5.407e-05 0.0005052
499 SALIVARY GLAND DEVELOPMENT 16 32 5.436e-05 0.0005059
500 ENDOCARDIAL CUSHION DEVELOPMENT 16 32 5.436e-05 0.0005059
501 TISSUE MIGRATION 31 84 5.534e-05 0.0005129
502 CYTOKINESIS 31 84 5.534e-05 0.0005129
503 REGULATION OF MUSCLE TISSUE DEVELOPMENT 36 103 5.572e-05 0.0005154
504 LUNG MORPHOGENESIS 20 45 5.711e-05 0.0005273
505 SINGLE ORGANISM BEHAVIOR 102 384 5.782e-05 0.000532
506 REGULATION OF MICROTUBULE BASED PROCESS 70 243 5.785e-05 0.000532
507 REGULATION OF PEPTIDE TRANSPORT 73 256 5.839e-05 0.0005359
508 ION TRANSPORT 287 1262 5.882e-05 0.0005383
509 LYMPHOCYTE DIFFERENTIATION 62 209 5.889e-05 0.0005383
510 PROTEIN LOCALIZATION TO CELL PERIPHERY 48 151 6.038e-05 0.0005509
511 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 47 147 6.107e-05 0.000555
512 REGULATION OF NEURON DEATH 72 252 6.104e-05 0.000555
513 REGULATION OF SODIUM ION TRANSPORT 29 77 6.198e-05 0.0005622
514 REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 24 59 6.28e-05 0.0005685
515 METANEPHROS DEVELOPMENT 30 81 6.711e-05 0.0006063
516 LEUKOCYTE DIFFERENTIATION 81 292 6.791e-05 0.0006118
517 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 35 100 6.798e-05 0.0006118
518 MYELOID CELL DIFFERENTIATION 57 189 6.951e-05 0.0006244
519 REGULATION OF RESPONSE TO WOUNDING 108 413 7.1e-05 0.0006365
520 REGULATION OF ACTIN FILAMENT LENGTH 49 156 7.141e-05 0.0006383
521 REGULATION OF IMMUNE SYSTEM PROCESS 315 1403 7.147e-05 0.0006383
522 SULFUR COMPOUND METABOLIC PROCESS 96 359 7.172e-05 0.0006393
523 GLOMERULUS DEVELOPMENT 21 49 7.219e-05 0.0006423
524 TRABECULA MORPHOGENESIS 18 39 7.264e-05 0.0006438
525 INTRINSIC APOPTOTIC SIGNALING PATHWAY 48 152 7.257e-05 0.0006438
526 REGULATION OF DENDRITIC SPINE DEVELOPMENT 23 56 7.43e-05 0.0006572
527 CELL CELL JUNCTION ASSEMBLY 28 74 7.49e-05 0.0006614
528 PROTEOLYSIS 275 1208 7.805e-05 0.0006878
529 LEUKOCYTE ACTIVATION 108 414 7.882e-05 0.0006933
530 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 94 351 7.992e-05 0.0007016
531 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 26 67 8.17e-05 0.0007159
532 PEPTIDYL THREONINE MODIFICATION 20 46 8.354e-05 0.0007307
533 PEPTIDYL TYROSINE MODIFICATION 56 186 8.426e-05 0.0007356
534 CELLULAR LIPID METABOLIC PROCESS 214 913 8.443e-05 0.0007357
535 REGULATION OF GLUCOSE IMPORT 24 60 8.642e-05 0.0007516
536 REGULATION OF METAL ION TRANSPORT 88 325 8.74e-05 0.0007573
537 INTEGRIN MEDIATED SIGNALING PATHWAY 30 82 8.724e-05 0.0007573
538 BEHAVIOR 130 516 8.782e-05 0.0007595
539 SYNAPSE ORGANIZATION 46 145 8.974e-05 0.0007733
540 MITOTIC NUCLEAR DIVISION 96 361 8.974e-05 0.0007733
541 REGULATION OF RECEPTOR ACTIVITY 39 117 9.209e-05 0.000791
542 REGULATION OF CELL CYCLE PHASE TRANSITION 87 321 9.214e-05 0.000791
543 SMOOTH MUSCLE CELL DIFFERENTIATION 15 30 9.298e-05 0.0007953
544 REGULATION OF DENDRITIC SPINE MORPHOGENESIS 15 30 9.298e-05 0.0007953
545 REGULATION OF CARDIAC MUSCLE CELL CONTRACTION 14 27 9.599e-05 0.0008195
546 ARTERY DEVELOPMENT 28 75 9.859e-05 0.0008401
547 REGULATION OF ION TRANSPORT 146 592 0.0001003 0.0008536
548 MUSCLE SYSTEM PROCESS 78 282 0.0001016 0.0008623
549 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 21 50 0.0001029 0.0008719
550 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 34 98 0.0001046 0.0008852
551 REGULATION OF LEUKOCYTE APOPTOTIC PROCESS 29 79 0.000106 0.0008935
552 REGULATION OF TRANSMEMBRANE TRANSPORT 110 426 0.000106 0.0008935
553 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 62 213 0.0001075 0.0009048
554 NEGATIVE REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 18 40 0.0001093 0.0009181
555 REGULATION OF ESTABLISHMENT OF PLANAR POLARITY 37 110 0.0001114 0.0009337
556 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 61 209 0.0001119 0.0009349
557 REGULATION OF APOPTOTIC SIGNALING PATHWAY 96 363 0.0001119 0.0009349
558 POST GOLGI VESICLE MEDIATED TRANSPORT 30 83 0.0001126 0.0009393
559 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 40 122 0.0001135 0.0009447
560 VENTRICULAR SEPTUM DEVELOPMENT 22 54 0.0001221 0.001015
561 ENSHEATHMENT OF NEURONS 32 91 0.0001235 0.001023
562 AXON ENSHEATHMENT 32 91 0.0001235 0.001023
563 PHOSPHOLIPID METABOLIC PROCESS 96 364 0.0001247 0.001031
564 TOR SIGNALING 10 16 0.0001261 0.00104
565 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 33 95 0.0001278 0.001053
566 LIPID MODIFICATION 61 210 0.0001296 0.001066
567 CARDIAC MUSCLE ADAPTATION 8 11 0.0001332 0.001087
568 MUSCLE HYPERTROPHY IN RESPONSE TO STRESS 8 11 0.0001332 0.001087
569 EPITHELIAL TO MESENCHYMAL TRANSITION INVOLVED IN ENDOCARDIAL CUSHION FORMATION 8 11 0.0001332 0.001087
570 CARDIAC MUSCLE HYPERTROPHY IN RESPONSE TO STRESS 8 11 0.0001332 0.001087
571 REGULATION OF MUSCLE ORGAN DEVELOPMENT 35 103 0.0001341 0.001093
572 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 43 135 0.0001352 0.0011
573 POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 16 34 0.0001368 0.001107
574 PROTEIN STABILIZATION 42 131 0.0001367 0.001107
575 REGIONALIZATION 84 311 0.0001367 0.001107
576 ANION TRANSPORT 127 507 0.0001372 0.001108
577 POSITIVE REGULATION OF BINDING 41 127 0.0001378 0.001111
578 POSITIVE REGULATION OF MITOTIC CELL CYCLE 40 123 0.0001385 0.001115
579 APOPTOTIC SIGNALING PATHWAY 79 289 0.00014 0.001125
580 SECOND MESSENGER MEDIATED SIGNALING 49 160 0.0001434 0.001151
581 CELLULAR RESPONSE TO ABIOTIC STIMULUS 73 263 0.0001479 0.001184
582 GLYCEROLIPID BIOSYNTHETIC PROCESS 61 211 0.0001499 0.001198
583 ESTABLISHMENT OF CELL POLARITY 31 88 0.0001508 0.001204
584 DIGESTIVE SYSTEM DEVELOPMENT 46 148 0.0001541 0.001228
585 CELLULAR RESPONSE TO KETONE 27 73 0.0001564 0.001244
586 MAMMARY GLAND DUCT MORPHOGENESIS 14 28 0.0001593 0.001265
587 AORTA DEVELOPMENT 18 41 0.0001613 0.001279
588 POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 34 100 0.0001639 0.001297
589 HISTONE PHOSPHORYLATION 13 25 0.0001647 0.001301
590 PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROCESS 39 120 0.0001692 0.001334
591 DIGESTIVE TRACT MORPHOGENESIS 20 48 0.0001705 0.001342
592 REGULATION OF CARDIAC MUSCLE CONTRACTION 25 66 0.0001749 0.001375
593 REGULATION OF JUN KINASE ACTIVITY 29 81 0.0001762 0.001382
594 ACTIN FILAMENT ORGANIZATION 52 174 0.0001817 0.001423
595 RESPONSE TO IONIZING RADIATION 45 145 0.0001876 0.001467
596 REGULATION OF CELL CYCLE G2 M PHASE TRANSITION 23 59 0.0001907 0.001485
597 VASCULOGENESIS 23 59 0.0001907 0.001485
598 REGULATION OF GENERATION OF PRECURSOR METABOLITES AND ENERGY 31 89 0.0001908 0.001485
599 REGULATION OF HEMOPOIESIS 84 314 0.0001932 0.001501
600 INTRACELLULAR PROTEIN TRANSPORT 184 781 0.0001966 0.001525
601 MULTI MULTICELLULAR ORGANISM PROCESS 61 213 0.0001992 0.001542
602 EXOCRINE SYSTEM DEVELOPMENT 19 45 0.0002001 0.001547
603 REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 33 97 0.0002005 0.001547
604 REGULATION OF PROTEIN KINASE B SIGNALING 39 121 0.0002056 0.001584
605 ORGANIC ANION TRANSPORT 100 387 0.000207 0.001584
606 METANEPHRIC MESENCHYME DEVELOPMENT 9 14 0.0002067 0.001584
607 POSITIVE REGULATION OF CELL SIZE 9 14 0.0002067 0.001584
608 REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 36 109 0.0002069 0.001584
609 REGULATION OF MUSCLE ADAPTATION 24 63 0.0002115 0.001616
610 RESPONSE TO INSULIN 59 205 0.0002172 0.001657
611 CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS 55 188 0.0002214 0.001686
612 KIDNEY MORPHOGENESIS 29 82 0.0002248 0.001707
613 CARDIAC CONDUCTION 29 82 0.0002248 0.001707
614 PLATELET ACTIVATION 44 142 0.0002284 0.00173
615 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 22 56 0.000229 0.00173
616 VESICLE DOCKING 22 56 0.000229 0.00173
617 NEGATIVE REGULATION OF BMP SIGNALING PATHWAY 18 42 0.0002337 0.001757
618 REGULATION OF ACTIN FILAMENT BASED MOVEMENT 15 32 0.0002332 0.001757
619 PLACENTA DEVELOPMENT 43 138 0.0002334 0.001757
620 INTERACTION WITH HOST 42 134 0.000238 0.001785
621 CARDIAC CELL DEVELOPMENT 20 49 0.0002383 0.001785
622 ACTION POTENTIAL 32 94 0.0002453 0.001835
623 NEGATIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 26 71 0.0002473 0.001847
624 SISTER CHROMATID SEGREGATION 52 176 0.0002482 0.001851
625 REGULATION OF CELL PROJECTION ASSEMBLY 47 155 0.0002502 0.001863
626 FORMATION OF PRIMARY GERM LAYER 36 110 0.0002534 0.001875
627 TRANSITION METAL ION HOMEOSTASIS 35 106 0.0002531 0.001875
628 REGULATION OF GLUCOSE METABOLIC PROCESS 35 106 0.0002531 0.001875
629 REGULATION OF EMBRYONIC DEVELOPMENT 37 114 0.0002527 0.001875
630 NEGATIVE REGULATION OF CELL DIVISION 23 60 0.0002555 0.001881
631 ORGANELLE TRANSPORT ALONG MICROTUBULE 23 60 0.0002555 0.001881
632 REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 10 17 0.0002553 0.001881
633 PROTEIN N LINKED GLYCOSYLATION 27 75 0.000262 0.001923
634 POSITIVE REGULATION OF AUTOPHAGY 27 75 0.000262 0.001923
635 REPLACEMENT OSSIFICATION 13 26 0.0002736 0.002002
636 ENDOCHONDRAL OSSIFICATION 13 26 0.0002736 0.002002
637 POSITIVE REGULATION OF PHOSPHOLIPASE ACTIVITY 21 53 0.0002746 0.002003
638 NEURON PROJECTION EXTENSION 21 53 0.0002746 0.002003
639 N GLYCAN PROCESSING 11 20 0.000279 0.002025
640 TRACHEA DEVELOPMENT 11 20 0.000279 0.002025
641 MITOTIC CELL CYCLE CHECKPOINT 43 139 0.0002782 0.002025
642 REGULATION OF PHOSPHOLIPASE ACTIVITY 24 64 0.0002795 0.002026
643 PROSTATE GLAND MORPHOGENESIS 12 23 0.0002831 0.002042
644 PROTEIN LOCALIZATION TO VACUOLE 19 46 0.0002822 0.002042
645 STRIATED MUSCLE ADAPTATION 12 23 0.0002831 0.002042
646 CELL CYCLE PHASE TRANSITION 70 255 0.0002844 0.002045
647 LEUKOCYTE CELL CELL ADHESION 70 255 0.0002844 0.002045
648 EMBRYONIC PLACENTA DEVELOPMENT 29 83 0.0002851 0.002047
649 POSITIVE REGULATION OF MAP KINASE ACTIVITY 59 207 0.0002877 0.002063
650 TRANSMEMBRANE TRANSPORT 248 1098 0.0002889 0.002068
651 NEGATIVE REGULATION OF BINDING 41 131 0.0002902 0.002074
652 MOVEMENT IN ENVIRONMENT OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 30 87 0.0002936 0.002076
653 ENTRY INTO CELL OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 30 87 0.0002936 0.002076
654 VIRAL ENTRY INTO HOST CELL 30 87 0.0002936 0.002076
655 ENTRY INTO OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 30 87 0.0002936 0.002076
656 MOVEMENT IN HOST ENVIRONMENT 30 87 0.0002936 0.002076
657 ENTRY INTO HOST 30 87 0.0002936 0.002076
658 ENTRY INTO HOST CELL 30 87 0.0002936 0.002076
659 MULTICELLULAR ORGANISMAL SIGNALING 39 123 0.0003001 0.002115
660 T CELL DIFFERENTIATION 39 123 0.0003001 0.002115
661 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 25 68 0.0003009 0.002118
662 ENDOTHELIAL CELL MIGRATION 22 57 0.0003083 0.002167
663 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 36 111 0.000309 0.002169
664 REPRODUCTION 288 1297 0.0003166 0.002219
665 FACE DEVELOPMENT 20 50 0.0003285 0.002299
666 CELLULAR RESPONSE TO PEPTIDE 74 274 0.0003311 0.002313
667 CHONDROITIN SULFATE PROTEOGLYCAN METABOLIC PROCESS 18 43 0.0003329 0.002322
668 POSITIVE REGULATION OF GLUCOSE IMPORT IN RESPONSE TO INSULIN STIMULUS 8 12 0.0003343 0.002329
669 NEURON RECOGNITION 15 33 0.0003547 0.002463
670 EMBRYONIC EYE MORPHOGENESIS 15 33 0.0003547 0.002463
671 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 60 213 0.0003609 0.002502
672 INNER EAR MORPHOGENESIS 31 92 0.0003733 0.002585
673 REGULATION OF PEPTIDE SECRETION 59 209 0.0003783 0.002615
674 SECRETION BY CELL 120 486 0.0003802 0.002625
675 REGULATION OF MEMBRANE POTENTIAL 89 343 0.0003868 0.002666
676 MITOTIC SPINDLE ORGANIZATION 25 69 0.0003897 0.002682
677 MAMMARY GLAND MORPHOGENESIS 17 40 0.0003906 0.002685
678 POSITIVE REGULATION OF ORGANELLE ASSEMBLY 19 47 0.0003921 0.002691
679 PROTEASOMAL PROTEIN CATABOLIC PROCESS 73 271 0.0003927 0.002691
680 REGULATION OF PROTEIN TARGETING 81 307 0.0003975 0.00272
681 NEURON MATURATION 14 30 0.0003981 0.00272
682 HINDBRAIN DEVELOPMENT 42 137 0.0004023 0.002745
683 POSITIVE REGULATION OF CYTOSKELETON ORGANIZATION 51 175 0.0004056 0.002763
684 NEGATIVE REGULATION OF NEURON DEATH 50 171 0.0004221 0.002867
685 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 50 171 0.0004221 0.002867
686 ACTOMYOSIN STRUCTURE ORGANIZATION 27 77 0.0004264 0.002892
687 REGULATION OF EPITHELIAL CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 9 15 0.0004317 0.002924
688 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 56 197 0.0004347 0.00294
689 HIPPO SIGNALING 13 27 0.0004385 0.002949
690 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 64 232 0.0004377 0.002949
691 REGULATION OF LEUKOCYTE DIFFERENTIATION 64 232 0.0004377 0.002949
692 CENTRAL NERVOUS SYSTEM NEURON AXONOGENESIS 13 27 0.0004385 0.002949
693 NEGATIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 20 51 0.0004472 0.002999
694 RESPONSE TO TOXIC SUBSTANCE 66 241 0.0004474 0.002999
695 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 95 372 0.0004523 0.003028
696 REGULATION OF LEUKOCYTE PROLIFERATION 58 206 0.0004537 0.003033
697 IMPORT INTO CELL 16 37 0.0004554 0.003036
698 AXON EXTENSION 16 37 0.0004554 0.003036
699 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 63 228 0.0004604 0.003065
700 CYTOSOLIC TRANSPORT 60 215 0.0004702 0.003125
701 OSTEOBLAST DEVELOPMENT 10 18 0.0004791 0.003175
702 CENTROSOME LOCALIZATION 10 18 0.0004791 0.003175
703 GASTRULATION 46 155 0.0004912 0.003251
704 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 64 233 0.000496 0.003278
705 EPIDERMAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 21 55 0.0004972 0.003281
706 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 78 296 0.0005238 0.003452
707 RESPONSE TO FLUID SHEAR STRESS 15 34 0.0005267 0.003462
708 REGULATION OF MUSCLE CONTRACTION 44 147 0.0005267 0.003462
709 REGULATION OF LIPID KINASE ACTIVITY 19 48 0.0005373 0.003526
710 LYMPHOCYTE COSTIMULATION 27 78 0.0005384 0.003528
711 MEMBRANE LIPID BIOSYNTHETIC PROCESS 36 114 0.0005466 0.003577
712 EXOCYTOSIS 81 310 0.0005483 0.003583
713 NEGATIVE REGULATION OF STRESS ACTIVATED MAPK CASCADE 17 41 0.000553 0.003604
714 NEGATIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 17 41 0.000553 0.003604
715 FAT CELL DIFFERENTIATION 34 106 0.0005612 0.003652
716 REGULATION OF EXOCYTOSIS 53 186 0.0005724 0.00372
717 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 41 135 0.0005791 0.003757
718 RESPONSE TO OSMOTIC STRESS 23 63 0.0005797 0.003757
719 ORGANIC HYDROXY COMPOUND METABOLIC PROCESS 118 482 0.0005977 0.003868
720 ION TRANSMEMBRANE TRANSPORT 189 822 0.0006021 0.003891
721 HEMOSTASIS 81 311 0.0006089 0.00393
722 REGULATION OF PROTEIN SECRETION 98 389 0.0006113 0.003939
723 SEX DIFFERENTIATION 71 266 0.0006182 0.003979
724 AUTOPHAGY 99 394 0.0006326 0.004065
725 PHOSPHOLIPID BIOSYNTHETIC PROCESS 64 235 0.000634 0.004069
726 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE 25 71 0.0006385 0.00409
727 CELLULAR CARBOHYDRATE METABOLIC PROCESS 43 144 0.000639 0.00409
728 REGULATION OF HORMONE SECRETION 70 262 0.000653 0.004157
729 NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 56 200 0.0006517 0.004157
730 ENDOPLASMIC RETICULUM ORGANIZATION 16 38 0.0006524 0.004157
731 MESENCHYME MORPHOGENESIS 16 38 0.0006524 0.004157
732 RESPONSE TO RADIATION 103 413 0.000658 0.004177
733 OUTFLOW TRACT MORPHOGENESIS 21 56 0.0006581 0.004177
734 ACTIVATION OF GTPASE ACTIVITY 26 75 0.0006595 0.004181
735 SISTER CHROMATID COHESION 35 111 0.0006678 0.004216
736 CELL CYCLE G1 S PHASE TRANSITION 35 111 0.0006678 0.004216
737 G1 S TRANSITION OF MITOTIC CELL CYCLE 35 111 0.0006678 0.004216
738 REGULATION OF STRIATED MUSCLE CONTRACTION 27 79 0.0006754 0.004258
739 PROTEIN COMPLEX SUBUNIT ORGANIZATION 331 1527 0.0006768 0.004261
740 VENTRICULAR SEPTUM MORPHOGENESIS 13 28 0.0006805 0.004265
741 HOMEOSTATIC PROCESS 293 1337 0.0006814 0.004265
742 POSITIVE REGULATION OF LEUKOCYTE PROLIFERATION 41 136 0.0006828 0.004265
743 MUSCLE HYPERTROPHY 13 28 0.0006805 0.004265
744 GLIAL CELL DIFFERENTIATION 41 136 0.0006828 0.004265
745 EYE MORPHOGENESIS 41 136 0.0006828 0.004265
746 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 190 829 0.0006879 0.00429
747 SECRETION 140 588 0.0006906 0.004302
748 GLYCOSYLATION 71 267 0.0006921 0.004305
749 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 45 153 0.0006941 0.004312
750 REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 31 95 0.000696 0.004318
751 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 22 60 0.000707 0.00438
752 NEURONAL STEM CELL DIVISION 8 13 0.0007277 0.004473
753 REGULATION OF VASCULOGENESIS 8 13 0.0007277 0.004473
754 HEPATICOBILIARY SYSTEM DEVELOPMENT 39 128 0.0007254 0.004473
755 PHOSPHATIDYLINOSITOL 3 PHOSPHATE BIOSYNTHETIC PROCESS 19 49 0.0007267 0.004473
756 PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 8 13 0.0007277 0.004473
757 NEUROBLAST DIVISION 8 13 0.0007277 0.004473
758 NEGATIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 47 162 0.0007439 0.004566
759 POSITIVE REGULATION OF DENDRITE DEVELOPMENT 23 64 0.0007481 0.00458
760 CELLULAR CHEMICAL HOMEOSTASIS 136 570 0.0007471 0.00458
761 SPINDLE CHECKPOINT 12 25 0.0007538 0.004597
762 CHONDROITIN SULFATE BIOSYNTHETIC PROCESS 12 25 0.0007538 0.004597
763 PROTEIN DEPOLYMERIZATION 12 25 0.0007538 0.004597
764 RESPONSE TO IRON ION 15 35 0.0007651 0.00466
765 DENDRITE MORPHOGENESIS 17 42 0.0007702 0.004678
766 AUTONOMIC NERVOUS SYSTEM DEVELOPMENT 17 42 0.0007702 0.004678
767 MEMBRANE DOCKING 24 68 0.0007816 0.004736
768 POSITIVE REGULATION OF CELL CYCLE PHASE TRANSITION 24 68 0.0007816 0.004736
769 MEMBRANE LIPID METABOLIC PROCESS 52 184 0.0007893 0.004776
770 MAMMARY GLAND EPITHELIUM DEVELOPMENT 20 53 0.0007995 0.004831
771 EAR MORPHOGENESIS 35 112 0.0008008 0.004833
772 SKELETAL MUSCLE ORGAN DEVELOPMENT 41 137 0.0008027 0.004838
773 ENERGY RESERVE METABOLIC PROCESS 25 72 0.0008081 0.004864
774 REGULATION OF PROTEIN HOMODIMERIZATION ACTIVITY 11 22 0.0008132 0.004866
775 REGULATION OF LIPID METABOLIC PROCESS 74 282 0.0008136 0.004866
776 POSITIVE REGULATION OF MUSCLE HYPERTROPHY 11 22 0.0008132 0.004866
777 CENTRAL NERVOUS SYSTEM PROJECTION NEURON AXONOGENESIS 11 22 0.0008132 0.004866
778 POSITIVE REGULATION OF CARDIAC MUSCLE HYPERTROPHY 11 22 0.0008132 0.004866
779 CELL PROJECTION ASSEMBLY 70 264 0.0008179 0.004883
780 ION HOMEOSTASIS 137 576 0.0008185 0.004883
781 RETINA VASCULATURE DEVELOPMENT IN CAMERA TYPE EYE 9 16 0.0008245 0.0049
782 CELL SURFACE RECEPTOR SIGNALING PATHWAY INVOLVED IN HEART DEVELOPMENT 9 16 0.0008245 0.0049
783 BRANCHING INVOLVED IN SALIVARY GLAND MORPHOGENESIS 9 16 0.0008245 0.0049
784 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 91 360 0.0008352 0.004957
785 LIMBIC SYSTEM DEVELOPMENT 32 100 0.0008402 0.00498
786 CIRCADIAN REGULATION OF GENE EXPRESSION 21 57 0.0008621 0.005104
787 LIPID METABOLIC PROCESS 256 1158 0.0008795 0.0052
788 STEROID HORMONE MEDIATED SIGNALING PATHWAY 38 125 0.0008831 0.005214
789 PATTERNING OF BLOOD VESSELS 14 32 0.0008904 0.005251
790 CHROMOSOME LOCALIZATION 22 61 0.0009146 0.00538
791 POSITIVE REGULATION OF STEM CELL PROLIFERATION 22 61 0.0009146 0.00538
792 ANATOMICAL STRUCTURE MATURATION 16 39 0.0009177 0.005385
793 VESICLE CYTOSKELETAL TRAFFICKING 16 39 0.0009177 0.005385
794 REGULATION OF PROTEIN COMPLEX ASSEMBLY 94 375 0.0009263 0.005428
795 RESPONSE TO CARBOHYDRATE 48 168 0.0009494 0.005556
796 SINGLE ORGANISM CATABOLIC PROCESS 215 957 0.0009589 0.005605
797 POSITIVE REGULATION OF CELL ACTIVATION 80 311 0.0009709 0.005668
798 NEGATIVE REGULATION OF CYTOSKELETON ORGANIZATION 60 221 0.0009976 0.005817
799 POSITIVE REGULATION OF PROTEIN BINDING 25 73 0.001016 0.005892
800 HIPPOCAMPUS DEVELOPMENT 25 73 0.001016 0.005892
801 REGULATION OF ORGAN GROWTH 25 73 0.001016 0.005892
802 REGULATION OF PLASMA MEMBRANE ORGANIZATION 25 73 0.001016 0.005892
803 ESTABLISHMENT OF LOCALIZATION BY MOVEMENT ALONG MICROTUBULE 31 97 0.001029 0.00596
804 RESPONSE TO CYTOKINE 165 714 0.00103 0.005963
805 SPHINGOLIPID BIOSYNTHETIC PROCESS 26 77 0.001033 0.005969
806 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 30 93 0.001039 0.005998
807 REGULATION OF PROTEIN POLYMERIZATION 49 173 0.001042 0.006003
808 RHYTHMIC PROCESS 77 298 0.001043 0.006003
809 REGULATION OF LYMPHOCYTE APOPTOTIC PROCESS 20 54 0.001051 0.006046
810 NEGATIVE REGULATION OF STEM CELL DIFFERENTIATION 17 43 0.001056 0.006059
811 CEREBRAL CORTEX CELL MIGRATION 17 43 0.001056 0.006059
812 CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 15 36 0.001089 0.006232
813 POSITIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 15 36 0.001089 0.006232
814 REGULATION OF CELL SHAPE 41 139 0.001099 0.006283
815 REGULATION OF MUSCLE CELL DIFFERENTIATION 44 152 0.001132 0.00646
816 REGULATION OF MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION 50 178 0.001138 0.006486
817 HEART TRABECULA MORPHOGENESIS 12 26 0.001165 0.006637
818 FOREBRAIN CELL MIGRATION 22 62 0.001173 0.006671
819 RESPONSE TO TRANSITION METAL NANOPARTICLE 43 148 0.00118 0.006705
820 POSITIVE REGULATION OF LIPASE ACTIVITY 23 66 0.001215 0.006895
821 URETER DEVELOPMENT 7 11 0.00122 0.006898
822 ESTABLISHMENT OF ENDOTHELIAL INTESTINAL BARRIER 7 11 0.00122 0.006898
823 PROSTATE GLAND GROWTH 7 11 0.00122 0.006898
824 MICROTUBULE BASED MOVEMENT 56 205 0.001233 0.006962
825 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 31 98 0.001241 0.006993
826 NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 31 98 0.001241 0.006993
827 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 16 40 0.001269 0.007141
828 MIDBRAIN DEVELOPMENT 29 90 0.001273 0.007155
829 ARTERY MORPHOGENESIS 19 51 0.001282 0.007193
830 REGULATION OF PROTEIN EXPORT FROM NUCLEUS 14 33 0.001285 0.007195
831 EMBRYONIC DIGESTIVE TRACT DEVELOPMENT 14 33 0.001285 0.007195
832 REGULATION OF ION HOMEOSTASIS 55 201 0.001299 0.007258
833 TRABECULA FORMATION 11 23 0.001299 0.007258
834 POSITIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 36 119 0.001309 0.007302
835 BONE GROWTH 10 20 0.001409 0.007822
836 SERTOLI CELL DIFFERENTIATION 10 20 0.001409 0.007822
837 BRANCHING INVOLVED IN MAMMARY GLAND DUCT MORPHOGENESIS 10 20 0.001409 0.007822
838 RESPONSE TO LEAD ION 10 20 0.001409 0.007822
839 INSULIN LIKE GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 8 14 0.001422 0.007889
840 BODY MORPHOGENESIS 17 44 0.001427 0.007906
841 ANATOMICAL STRUCTURE ARRANGEMENT 9 17 0.001465 0.008066
842 REGULATION OF CHROMATIN BINDING 9 17 0.001465 0.008066
843 REGULATION OF PLATELET AGGREGATION 9 17 0.001465 0.008066
844 POSITIVE REGULATION OF GLYCOGEN METABOLIC PROCESS 9 17 0.001465 0.008066
845 NEGATIVE REGULATION OF ANOIKIS 9 17 0.001465 0.008066
846 POSITIVE REGULATION OF JUN KINASE ACTIVITY 22 63 0.001491 0.0082
847 CHONDROITIN SULFATE PROTEOGLYCAN BIOSYNTHETIC PROCESS 13 30 0.001506 0.008251
848 NEGATIVE REGULATION OF TOR SIGNALING 13 30 0.001506 0.008251
849 RESPONSE TO X RAY 13 30 0.001506 0.008251
850 CARBOHYDRATE TRANSPORT 30 95 0.00152 0.008316
851 CARDIAC MUSCLE CELL ACTION POTENTIAL 15 37 0.001521 0.008316
852 ALCOHOL METABOLIC PROCESS 87 348 0.001524 0.008325
853 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 23 67 0.00153 0.008348
854 REGULATION OF LIPASE ACTIVITY 27 83 0.001573 0.008568
855 ERBB SIGNALING PATHWAY 26 79 0.001576 0.008569
856 REGULATION OF PROTEOLYSIS 163 711 0.001576 0.008569
857 RESPONSE TO TOPOLOGICALLY INCORRECT PROTEIN 46 163 0.001578 0.008569
858 CELLULAR RESPONSE TO INSULIN STIMULUS 42 146 0.00165 0.008937
859 DNA INTEGRITY CHECKPOINT 42 146 0.00165 0.008937
860 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 38 129 0.001679 0.009084
861 LOCOMOTORY BEHAVIOR 50 181 0.001684 0.009102
862 INTRACELLULAR RECEPTOR SIGNALING PATHWAY 47 168 0.00172 0.009283
863 MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION 16 41 0.001728 0.009314
864 MOTOR NEURON AXON GUIDANCE 12 27 0.001747 0.009396
865 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 12 27 0.001747 0.009396
866 REGULATION OF PROTEIN COMPLEX DISASSEMBLY 58 217 0.001781 0.009567
867 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 36 121 0.00181 0.009712
868 PLATELET DERIVED GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 14 34 0.001816 0.009723
869 CAMP METABOLIC PROCESS 14 34 0.001816 0.009723
870 MATERNAL PROCESS INVOLVED IN FEMALE PREGNANCY 21 60 0.001831 0.00979
NumGOOverlapSizeP ValueAdj. P Value
1 ENZYME BINDING 521 1737 3.869e-34 3.595e-31
2 CYTOSKELETAL PROTEIN BINDING 266 819 1.076e-22 4.998e-20
3 RIBONUCLEOTIDE BINDING 505 1860 4.833e-22 1.323e-19
4 MACROMOLECULAR COMPLEX BINDING 401 1399 5.698e-22 1.323e-19
5 KINASE ACTIVITY 263 842 7.858e-20 1.46e-17
6 ADENYL NUCLEOTIDE BINDING 412 1514 3.742e-18 5.794e-16
7 PROTEIN KINASE ACTIVITY 206 640 2.623e-17 3.481e-15
8 PROTEIN DOMAIN SPECIFIC BINDING 201 624 5.93e-17 6.886e-15
9 KINASE BINDING 195 606 1.98e-16 2.044e-14
10 PROTEIN COMPLEX BINDING 269 935 3.707e-15 3.355e-13
11 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 282 992 3.972e-15 3.355e-13
12 PROTEIN SERINE THREONINE KINASE ACTIVITY 150 445 8.957e-15 6.935e-13
13 MOLECULAR FUNCTION REGULATOR 358 1353 6.038e-14 4.315e-12
14 ACTIN BINDING 133 393 2.136e-13 1.417e-11
15 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 315 1199 5.722e-12 3.544e-10
16 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 112 328 8.886e-12 5.159e-10
17 REGULATORY REGION NUCLEIC ACID BINDING 226 818 4.993e-11 2.728e-09
18 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 182 629 7.43e-11 3.835e-09
19 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 170 588 3.386e-10 1.656e-08
20 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 103 315 9.669e-10 4.389e-08
21 PHOSPHORIC ESTER HYDROLASE ACTIVITY 116 368 1.039e-09 4.389e-08
22 RECEPTOR BINDING 363 1476 1.027e-09 4.389e-08
23 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 80 226 1.216e-09 4.913e-08
24 IDENTICAL PROTEIN BINDING 305 1209 1.573e-09 6.087e-08
25 PHOSPHATASE ACTIVITY 92 275 2.061e-09 7.657e-08
26 ENZYME REGULATOR ACTIVITY 249 959 3.527e-09 1.26e-07
27 PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 66 178 3.986e-09 1.371e-07
28 SEQUENCE SPECIFIC DNA BINDING 265 1037 5.538e-09 1.838e-07
29 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 97 303 9.976e-09 3.196e-07
30 SMAD BINDING 34 72 2.599e-08 8.047e-07
31 UBIQUITIN LIKE PROTEIN TRANSFERASE ACTIVITY 123 420 4.241e-08 1.271e-06
32 TUBULIN BINDING 87 273 7.103e-08 2.062e-06
33 GROWTH FACTOR BINDING 48 123 8.229e-08 2.317e-06
34 GTPASE BINDING 92 295 9.414e-08 2.572e-06
35 TRANSCRIPTION FACTOR BINDING 145 524 1.366e-07 3.625e-06
36 MICROTUBULE BINDING 68 201 1.542e-07 3.979e-06
37 DOUBLE STRANDED DNA BINDING 198 764 1.704e-07 4.279e-06
38 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 35 81 2.556e-07 6.088e-06
39 ZINC ION BINDING 281 1155 2.543e-07 6.088e-06
40 PHOSPHATIDYLINOSITOL BINDING 67 200 2.869e-07 6.664e-06
41 CHEMOREPELLENT ACTIVITY 17 27 4.341e-07 9.837e-06
42 SEMAPHORIN RECEPTOR BINDING 15 22 4.608e-07 1.019e-05
43 PROTEIN HOMODIMERIZATION ACTIVITY 186 722 6.211e-07 1.311e-05
44 CHROMATIN BINDING 122 435 6.208e-07 1.311e-05
45 HISTONE DEACETYLASE BINDING 41 105 6.923e-07 1.429e-05
46 PROTEIN COMPLEX SCAFFOLD 30 68 1.056e-06 2.133e-05
47 ENZYME ACTIVATOR ACTIVITY 129 471 1.198e-06 2.368e-05
48 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 72 228 1.343e-06 2.599e-05
49 PHOSPHOLIPID TRANSLOCATING ATPASE ACTIVITY 12 16 1.393e-06 2.641e-05
50 CELL ADHESION MOLECULE BINDING 61 186 2.129e-06 3.955e-05
51 NUCLEOSIDE TRIPHOSPHATASE REGULATOR ACTIVITY 95 329 2.761e-06 5.029e-05
52 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 28 64 2.933e-06 5.239e-05
53 TRANSITION METAL ION BINDING 325 1400 3.034e-06 5.319e-05
54 PROTEIN DIMERIZATION ACTIVITY 272 1149 4.217e-06 7.254e-05
55 GUANYL NUCLEOTIDE BINDING 108 390 5.032e-06 8.499e-05
56 INTEGRIN BINDING 39 105 5.408e-06 8.813e-05
57 LIPID BINDING 167 657 5.404e-06 8.813e-05
58 WNT PROTEIN BINDING 17 31 6.384e-06 0.0001023
59 PROTEIN TYROSINE KINASE ACTIVITY 57 176 6.957e-06 0.0001095
60 PROTEIN TYROSINE PHOSPHATASE ACTIVITY 38 103 8.523e-06 0.000132
61 MAGNESIUM ION BINDING 62 199 1.134e-05 0.0001727
62 SH3 DOMAIN BINDING 41 116 1.293e-05 0.0001938
63 COLLAGEN BINDING 27 65 1.417e-05 0.0002089
64 UBIQUITIN LIKE PROTEIN LIGASE BINDING 77 264 1.579e-05 0.0002293
65 PHOSPHOLIPID BINDING 99 360 1.67e-05 0.0002386
66 HYDROLASE ACTIVITY ACTING ON ACID ANHYDRIDES 199 820 1.739e-05 0.0002448
67 CORE PROMOTER PROXIMAL REGION DNA BINDING 101 371 2.168e-05 0.0003006
68 ION CHANNEL BINDING 39 111 2.432e-05 0.0003322
69 PHOSPHATIDYLINOSITOL PHOSPHATE BINDING 40 116 3.163e-05 0.0004238
70 RECEPTOR SIGNALING PROTEIN ACTIVITY 54 172 3.194e-05 0.0004238
71 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 53 168 3.246e-05 0.0004247
72 CORE PROMOTER BINDING 49 152 3.395e-05 0.0004381
73 GLYCOPROTEIN BINDING 36 101 3.459e-05 0.0004402
74 BINDING BRIDGING 54 173 3.816e-05 0.0004791
75 EXTRACELLULAR MATRIX BINDING 22 51 4.332e-05 0.0005365
76 PHOSPHOLIPID TRANSPORTER ACTIVITY 21 48 4.992e-05 0.0006102
77 TRANSCRIPTION COREPRESSOR ACTIVITY 65 221 5.278e-05 0.0006368
78 NEUROPILIN BINDING 10 15 5.674e-05 0.0006758
79 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 27 70 6.796e-05 0.0007991
80 CALCIUM ION BINDING 169 697 7.718e-05 0.0008852
81 NOTCH BINDING 11 18 7.628e-05 0.0008852
82 KINASE REGULATOR ACTIVITY 56 186 8.426e-05 0.0009546
83 PROTEIN SERINE THREONINE PHOSPHATASE ACTIVITY 25 64 9.811e-05 0.001098
84 CALMODULIN BINDING 54 179 0.0001054 0.001165
85 PLATELET DERIVED GROWTH FACTOR BINDING 8 11 0.0001332 0.001455
86 WNT ACTIVATED RECEPTOR ACTIVITY 12 22 0.0001628 0.001758
87 STEROID HORMONE RECEPTOR ACTIVITY 23 59 0.0001907 0.002013
88 TRANSCRIPTION COACTIVATOR ACTIVITY 80 296 0.0001901 0.002013
89 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 42 133 0.0001985 0.002072
90 RHO GTPASE BINDING 28 78 0.0002148 0.002217
91 PROTEIN SERINE THREONINE TYROSINE KINASE ACTIVITY 17 39 0.0002711 0.002767
92 GTPASE ACTIVITY 68 246 0.0002778 0.002806
93 UBIQUITIN LIKE PROTEIN LIGASE ACTIVITY 57 199 0.0003146 0.003142
94 EXTRACELLULAR MATRIX STRUCTURAL CONSTITUENT 27 76 0.0003354 0.003315
95 BETA CATENIN BINDING 29 84 0.0003592 0.003513
96 RECEPTOR SIGNALING PROTEIN SERINE THREONINE KINASE ACTIVITY 31 92 0.0003733 0.003613
97 PHOSPHATIDYLINOSITOL 3 KINASE BINDING 14 30 0.0003981 0.003812
98 RHO GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 27 77 0.0004264 0.004042
99 ACTIN FILAMENT BINDING 38 121 0.00044 0.004129
100 CORE PROMOTER SEQUENCE SPECIFIC DNA BINDING 33 101 0.0004642 0.004312
101 EPHRIN RECEPTOR BINDING 12 24 0.000471 0.004332
102 UBIQUITIN LIKE PROTEIN CONJUGATING ENZYME BINDING 15 34 0.0005267 0.004751
103 SIGNALING ADAPTOR ACTIVITY 26 74 0.0005217 0.004751
104 PDZ DOMAIN BINDING 30 90 0.0005658 0.005054
105 ORGANIC ANION TRANSMEMBRANE TRANSPORTER ACTIVITY 51 178 0.0006261 0.00554
106 CORECEPTOR ACTIVITY 16 38 0.0006524 0.005718
107 CYCLIN DEPENDENT PROTEIN SERINE THREONINE KINASE REGULATOR ACTIVITY 13 28 0.0006805 0.005908
108 METALLOPEPTIDASE ACTIVITY 53 188 0.0007529 0.006476
109 SODIUM CHANNEL REGULATOR ACTIVITY 14 32 0.0008904 0.007589
110 TRANSITION METAL ION TRANSMEMBRANE TRANSPORTER ACTIVITY 16 39 0.0009177 0.007751
111 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 33 105 0.0009976 0.008349
112 PROTEIN C TERMINUS BINDING 52 186 0.001032 0.008483
113 SH2 DOMAIN BINDING 13 29 0.001026 0.008483
114 SEMAPHORIN RECEPTOR ACTIVITY 7 11 0.00122 0.009943
NumGOOverlapSizeP ValueAdj. P Value
1 CELL JUNCTION 351 1151 3.178e-24 1.856e-21
2 ANCHORING JUNCTION 182 489 5.998e-23 1.751e-20
3 MEMBRANE REGION 337 1134 3.165e-21 6.161e-19
4 CELL PROJECTION 478 1786 1.629e-19 1.992e-17
5 GOLGI APPARATUS 402 1445 1.706e-19 1.992e-17
6 CELL SUBSTRATE JUNCTION 147 398 2.042e-18 1.988e-16
7 NEURON PROJECTION 281 942 4.745e-18 3.958e-16
8 CYTOSKELETON 505 1967 8.423e-17 6.149e-15
9 NEURON PART 350 1265 1.219e-16 7.911e-15
10 VACUOLE 329 1180 3.42e-16 1.997e-14
11 PLASMA MEMBRANE REGION 271 929 4.447e-16 2.361e-14
12 CELL LEADING EDGE 125 350 1.364e-14 6.126e-13
13 ENDOSOME 234 793 1.283e-14 6.126e-13
14 PERINUCLEAR REGION OF CYTOPLASM 196 642 5.761e-14 2.243e-12
15 MEMBRANE MICRODOMAIN 107 288 5.72e-14 2.243e-12
16 GOLGI APPARATUS PART 253 893 1.7e-13 6.206e-12
17 SYNAPSE 218 754 1.013e-12 3.481e-11
18 AXON 132 418 6.467e-11 2.098e-09
19 CELL PROJECTION PART 254 946 7.343e-11 2.257e-09
20 ACTIN CYTOSKELETON 138 444 8.225e-11 2.402e-09
21 CELL CELL JUNCTION 122 383 1.854e-10 5.155e-09
22 SOMATODENDRITIC COMPARTMENT 185 650 2.284e-10 6.063e-09
23 GOLGI MEMBRANE 197 703 2.497e-10 6.34e-09
24 VACUOLAR PART 194 694 4.281e-10 1.042e-08
25 MICROTUBULE CYTOSKELETON 276 1068 7.944e-10 1.784e-08
26 LAMELLIPODIUM 66 172 7.697e-10 1.784e-08
27 VACUOLAR MEMBRANE 168 587 9.894e-10 2.14e-08
28 ENDOPLASMIC RETICULUM 395 1631 1.346e-09 2.807e-08
29 APICAL PART OF CELL 113 361 2.668e-09 5.373e-08
30 EXCITATORY SYNAPSE 71 197 4.274e-09 8.32e-08
31 CYTOSKELETAL PART 350 1436 6.17e-09 1.162e-07
32 DENDRITE 132 451 1.426e-08 2.602e-07
33 CELL SURFACE 201 757 1.927e-08 3.41e-07
34 CYTOPLASMIC REGION 92 287 2.209e-08 3.795e-07
35 INTRACELLULAR VESICLE 308 1259 3.685e-08 6.149e-07
36 CELL CORTEX 79 238 4.055e-08 6.579e-07
37 EXTRACELLULAR MATRIX COMPONENT 49 125 5.126e-08 8.09e-07
38 BASOLATERAL PLASMA MEMBRANE 71 211 1.055e-07 1.622e-06
39 FILOPODIUM 39 94 2.002e-07 2.997e-06
40 RUFFLE 56 156 2.069e-07 3.021e-06
41 SYNAPSE PART 162 610 4.559e-07 6.494e-06
42 CELL CELL CONTACT ZONE 29 64 8.056e-07 1.12e-05
43 INTRINSIC COMPONENT OF PLASMA MEMBRANE 380 1649 9.062e-07 1.231e-05
44 SPINDLE 87 289 1.112e-06 1.476e-05
45 MICROTUBULE 114 405 1.18e-06 1.531e-05
46 CELL PROJECTION MEMBRANE 89 298 1.221e-06 1.551e-05
47 CELL CORTEX PART 44 119 1.606e-06 1.995e-05
48 PROTEINACEOUS EXTRACELLULAR MATRIX 102 356 1.778e-06 2.126e-05
49 APICAL PLASMA MEMBRANE 87 292 1.784e-06 2.126e-05
50 RECYCLING ENDOSOME 47 131 1.935e-06 2.26e-05
51 ENDOPLASMIC RETICULUM PART 276 1163 2.902e-06 3.323e-05
52 ENDOSOMAL PART 118 430 3.037e-06 3.411e-05
53 INTERCALATED DISC 24 51 3.101e-06 3.417e-05
54 SITE OF POLARIZED GROWTH 51 149 3.568e-06 3.859e-05
55 CELL BODY 132 494 3.69e-06 3.918e-05
56 CATALYTIC COMPLEX 249 1038 3.904e-06 4.071e-05
57 BASEMENT MEMBRANE 36 93 4.099e-06 4.2e-05
58 KINESIN COMPLEX 25 55 4.262e-06 4.291e-05
59 MICROTUBULE ORGANIZING CENTER 160 623 4.536e-06 4.49e-05
60 PROTEIN KINASE COMPLEX 35 90 4.91e-06 4.779e-05
61 TRANSFERASE COMPLEX 177 703 5.291e-06 5.065e-05
62 EXTRACELLULAR MATRIX 116 426 5.459e-06 5.142e-05
63 MIDBODY 46 132 6.105e-06 5.659e-05
64 CORTICAL CYTOSKELETON 32 81 8.382e-06 7.531e-05
65 COMPLEX OF COLLAGEN TRIMERS 14 23 8.265e-06 7.531e-05
66 HETEROCHROMATIN 28 67 8.604e-06 7.613e-05
67 EARLY ENDOSOME 86 301 1.248e-05 0.0001085
68 PLASMA MEMBRANE RAFT 33 86 1.263e-05 0.0001085
69 CORTICAL ACTIN CYTOSKELETON 25 58 1.352e-05 0.0001145
70 CHROMOSOME CENTROMERIC REGION 55 174 2.189e-05 0.0001826
71 LEADING EDGE MEMBRANE 45 134 2.249e-05 0.000185
72 POSTSYNAPSE 102 378 2.929e-05 0.0002375
73 ACTIN BASED CELL PROJECTION 56 181 3.659e-05 0.0002928
74 AXON PART 65 219 3.89e-05 0.000307
75 ORGANELLE SUBCOMPARTMENT 86 311 4.667e-05 0.0003634
76 LYTIC VACUOLE 133 526 6.139e-05 0.0004718
77 APICAL JUNCTION COMPLEX 42 128 7.605e-05 0.0005768
78 MICROTUBULE ASSOCIATED COMPLEX 46 145 8.974e-05 0.0006719
79 NEURON SPINE 40 121 9.267e-05 0.0006781
80 SARCOLEMMA 41 125 9.29e-05 0.0006781
81 UBIQUITIN LIGASE COMPLEX 73 262 0.0001301 0.0009378
82 RUFFLE MEMBRANE 29 80 0.0001371 0.0009766
83 TRANSFERASE COMPLEX TRANSFERRING PHOSPHORUS CONTAINING GROUPS 67 237 0.0001518 0.001068
84 KINETOCHORE 39 120 0.0001692 0.001176
85 CENTROSOME 122 487 0.0001832 0.001258
86 PODOSOME 12 23 0.0002831 0.001922
87 SIDE OF MEMBRANE 108 428 0.0003125 0.002098
88 LATE ENDOSOME 60 213 0.0003609 0.002395
89 NUCLEAR OUTER MEMBRANE ENDOPLASMIC RETICULUM MEMBRANE NETWORK 228 1005 0.0003876 0.002543
90 PROTEIN COMPLEX INVOLVED IN CELL ADHESION 14 30 0.0003981 0.002583
91 ACTOMYOSIN 23 62 0.0004452 0.002857
92 VESICLE MEMBRANE 125 512 0.0004705 0.002987
93 FILOPODIUM MEMBRANE 10 18 0.0004791 0.003008
94 RECEPTOR COMPLEX 85 327 0.0004853 0.003015
95 CONTRACTILE FIBER 59 211 0.0004937 0.003035
96 EXTRINSIC COMPONENT OF MEMBRANE 68 252 0.0005775 0.003513
97 CELL DIVISION SITE 20 52 0.0006014 0.003621
98 ENDOPLASMIC RETICULUM LUMEN 56 201 0.0007431 0.004428
99 RECYCLING ENDOSOME MEMBRANE 17 42 0.0007702 0.004543
100 I BAND 37 121 0.0009087 0.005307
101 CHROMATIN 108 441 0.0009806 0.00567
102 PML BODY 31 97 0.001029 0.005889
103 CELL CELL ADHERENS JUNCTION 20 54 0.001051 0.005903
104 NEUROMUSCULAR JUNCTION 20 54 0.001051 0.005903
105 SEMAPHORIN RECEPTOR COMPLEX 7 11 0.00122 0.006786
106 CHROMOSOME 198 880 0.001388 0.007647
107 PROTEIN PHOSPHATASE TYPE 2A COMPLEX 10 20 0.001409 0.007689
108 TRANS GOLGI NETWORK 53 193 0.001442 0.007799
109 PHOSPHATASE COMPLEX 18 48 0.001562 0.008368
110 LYTIC VACUOLE MEMBRANE 71 275 0.00163 0.008652
111 SPINDLE MIDZONE 12 27 0.001747 0.00919
112 AGGRESOME 14 34 0.001816 0.009468
113 T TUBULE 17 45 0.001903 0.009747
114 COLLAGEN TRIMER 28 88 0.001891 0.009747

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04510_Focal_adhesion 78 200 8.883e-12 1.599e-09
2 hsa04360_Axon_guidance 56 130 8.531e-11 5.415e-09
3 hsa04151_PI3K_AKT_signaling_pathway 115 351 9.025e-11 5.415e-09
4 hsa04390_Hippo_signaling_pathway 62 154 2.567e-10 1.091e-08
5 hsa04310_Wnt_signaling_pathway 61 151 3.031e-10 1.091e-08
6 hsa04010_MAPK_signaling_pathway 87 268 2.758e-08 8.274e-07
7 hsa04014_Ras_signaling_pathway 76 236 2.914e-07 7.127e-06
8 hsa04512_ECM.receptor_interaction 36 85 3.168e-07 7.127e-06
9 hsa04810_Regulation_of_actin_cytoskeleton 70 214 4.383e-07 8.767e-06
10 hsa04070_Phosphatidylinositol_signaling_system 31 78 9.989e-06 0.0001798
11 hsa04144_Endocytosis 63 203 1.111e-05 0.0001818
12 hsa04916_Melanogenesis 37 101 1.34e-05 0.0001978
13 hsa04110_Cell_cycle 44 128 1.428e-05 0.0001978
14 hsa04350_TGF.beta_signaling_pathway 32 85 2.668e-05 0.000343
15 hsa04520_Adherens_junction 28 73 5.646e-05 0.0006775
16 hsa04722_Neurotrophin_signaling_pathway 42 127 6.209e-05 0.0006986
17 hsa04540_Gap_junction 32 90 9.718e-05 0.001029
18 hsa04012_ErbB_signaling_pathway 31 87 0.0001185 0.001185
19 hsa04660_T_cell_receptor_signaling_pathway 36 108 0.0001682 0.001526
20 hsa04270_Vascular_smooth_muscle_contraction 38 116 0.0001695 0.001526
21 hsa04971_Gastric_acid_secretion 27 74 0.0002032 0.001666
22 hsa04912_GnRH_signaling_pathway 34 101 0.0002036 0.001666
23 hsa04910_Insulin_signaling_pathway 43 138 0.0002334 0.001827
24 hsa04114_Oocyte_meiosis 37 114 0.0002527 0.001896
25 hsa04914_Progesterone.mediated_oocyte_maturation 30 87 0.0002936 0.002114
26 hsa04115_p53_signaling_pathway 25 69 0.0003897 0.002698
27 hsa04970_Salivary_secretion 30 89 0.0004572 0.003048
28 hsa04920_Adipocytokine_signaling_pathway 24 68 0.0007816 0.005025
29 hsa04141_Protein_processing_in_endoplasmic_reticulum 48 168 0.0009494 0.005893
30 hsa00534_Glycosaminoglycan_biosynthesis_._heparan_sulfate 12 26 0.001165 0.006992
31 hsa04666_Fc_gamma_R.mediated_phagocytosis 30 95 0.00152 0.008824
32 hsa04960_Aldosterone.regulated_sodium_reabsorption 16 42 0.002317 0.01303
33 hsa04320_Dorso.ventral_axis_formation 11 25 0.002979 0.01625
34 hsa04662_B_cell_receptor_signaling_pathway 24 75 0.003544 0.01876
35 hsa04514_Cell_adhesion_molecules_.CAMs. 38 136 0.004593 0.02362
36 hsa04974_Protein_digestion_and_absorption 25 81 0.005026 0.02513
37 hsa04530_Tight_junction 37 133 0.005522 0.02686
38 hsa04720_Long.term_potentiation 22 70 0.006475 0.02989
39 hsa04730_Long.term_depression 22 70 0.006475 0.02989
40 hsa04120_Ubiquitin_mediated_proteolysis 38 139 0.006779 0.03051
41 hsa04020_Calcium_signaling_pathway 46 177 0.008591 0.03771
42 hsa04380_Osteoclast_differentiation 35 128 0.009057 0.03881
43 hsa04062_Chemokine_signaling_pathway 48 189 0.0115 0.04816
44 hsa00410_beta.Alanine_metabolism 9 22 0.01234 0.0495
45 hsa00562_Inositol_phosphate_metabolism 18 57 0.01238 0.0495
46 hsa00510_N.Glycan_biosynthesis 16 49 0.01275 0.0499
47 hsa04972_Pancreatic_secretion 28 101 0.0151 0.05781
48 hsa04976_Bile_secretion 21 71 0.01591 0.05965
49 hsa00564_Glycerophospholipid_metabolism 23 80 0.01697 0.06232
50 hsa04210_Apoptosis 25 89 0.01771 0.06377
51 hsa04340_Hedgehog_signaling_pathway 17 56 0.02199 0.07761
52 hsa04150_mTOR_signaling_pathway 16 52 0.02276 0.07877
53 hsa00640_Propanoate_metabolism 11 32 0.02452 0.08326
54 hsa00533_Glycosaminoglycan_biosynthesis_._keratan_sulfate 6 15 0.04391 0.1437
55 hsa00604_Glycosphingolipid_biosynthesis_._ganglio_series 6 15 0.04391 0.1437
56 hsa04964_Proximal_tubule_bicarbonate_reclamation 8 23 0.04847 0.1549
57 hsa04664_Fc_epsilon_RI_signaling_pathway 21 79 0.04904 0.1549
58 hsa04962_Vasopressin.regulated_water_reabsorption 13 44 0.05141 0.1569
59 hsa04973_Carbohydrate_digestion_and_absorption 13 44 0.05141 0.1569
60 hsa00600_Sphingolipid_metabolism 12 40 0.05387 0.1616
61 hsa04672_Intestinal_immune_network_for_IgA_production 14 49 0.05725 0.1689
62 hsa00561_Glycerolipid_metabolism 14 50 0.06646 0.193
63 hsa00340_Histidine_metabolism 9 29 0.07342 0.2098
64 hsa04630_Jak.STAT_signaling_pathway 36 155 0.08246 0.2319
65 hsa00532_Glycosaminoglycan_biosynthesis_._chondroitin_sulfate 7 22 0.09663 0.2673
66 hsa00630_Glyoxylate_and_dicarboxylate_metabolism 6 18 0.09951 0.2673
67 hsa00670_One_carbon_pool_by_folate 6 18 0.09951 0.2673
68 hsa00030_Pentose_phosphate_pathway 8 27 0.1113 0.2947
69 hsa00270_Cysteine_and_methionine_metabolism 10 36 0.1151 0.3001
70 hsa04710_Circadian_rhythm_._mammal 7 23 0.1177 0.3027
71 hsa04146_Peroxisome 19 79 0.1324 0.3358
72 hsa04370_VEGF_signaling_pathway 18 76 0.1559 0.3897
73 hsa00520_Amino_sugar_and_nucleotide_sugar_metabolism 12 48 0.1652 0.4073
74 hsa00020_Citrate_cycle_.TCA_cycle. 8 30 0.178 0.4329
75 hsa00360_Phenylalanine_metabolism 5 17 0.1937 0.4649
76 hsa00051_Fructose_and_mannose_metabolism 9 36 0.2109 0.4901
77 hsa04130_SNARE_interactions_in_vesicular_transport 9 36 0.2109 0.4901
78 hsa00010_Glycolysis_._Gluconeogenesis 15 65 0.2124 0.4901
79 hsa00052_Galactose_metabolism 7 27 0.2219 0.5056
80 hsa00910_Nitrogen_metabolism 6 23 0.2431 0.5415
81 hsa04330_Notch_signaling_pathway 11 47 0.2437 0.5415
82 hsa00603_Glycosphingolipid_biosynthesis_._globo_series 4 14 0.2523 0.5471
83 hsa03450_Non.homologous_end.joining 4 14 0.2523 0.5471
84 hsa00071_Fatty_acid_metabolism 10 43 0.265 0.5659
85 hsa04640_Hematopoietic_cell_lineage 19 88 0.2672 0.5659
86 hsa00430_Taurine_and_hypotaurine_metabolism 3 10 0.2783 0.5758
87 hsa04122_Sulfur_relay_system 3 10 0.2783 0.5758
88 hsa00310_Lysine_degradation 10 44 0.2904 0.594
89 hsa00750_Vitamin_B6_metabolism 2 6 0.3086 0.6196
90 hsa00563_Glycosylphosphatidylinositol.GPI..anchor_biosynthesis 6 25 0.3123 0.6196
91 hsa00512_Mucin_type_O.Glycan_biosynthesis 7 30 0.3151 0.6196
92 hsa00620_Pyruvate_metabolism 9 40 0.3167 0.6196
93 hsa04670_Leukocyte_transendothelial_migration 24 117 0.3249 0.6288
94 hsa00770_Pantothenate_and_CoA_biosynthesis 4 16 0.3432 0.6572
95 hsa03022_Basal_transcription_factors 8 37 0.377 0.7136
96 hsa00250_Alanine._aspartate_and_glutamate_metabolism 7 32 0.3806 0.7136
97 hsa04610_Complement_and_coagulation_cascades 14 69 0.4004 0.743
98 hsa00330_Arginine_and_proline_metabolism 11 54 0.4173 0.7666
99 hsa04620_Toll.like_receptor_signaling_pathway 20 102 0.429 0.7752
100 hsa00280_Valine._leucine_and_isoleucine_degradation 9 44 0.4306 0.7752
101 hsa00920_Sulfur_metabolism 3 13 0.4433 0.7901
102 hsa00480_Glutathione_metabolism 10 50 0.4508 0.7955
103 hsa04260_Cardiac_muscle_contraction 15 77 0.4607 0.7973
104 hsa00531_Glycosaminoglycan_degradation 4 19 0.4792 0.82
105 hsa04142_Lysosome 23 121 0.4829 0.82
106 hsa00072_Synthesis_and_degradation_of_ketone_bodies 2 9 0.5183 0.8718
107 hsa00380_Tryptophan_metabolism 8 42 0.528 0.8799
108 hsa00230_Purine_metabolism 30 162 0.5336 0.8812
109 hsa00601_Glycosphingolipid_biosynthesis_._lacto_and_neolacto_series 5 26 0.5424 0.8819
110 hsa04621_NOD.like_receptor_signaling_pathway 11 59 0.5438 0.8819
111 hsa04650_Natural_killer_cell_mediated_cytotoxicity 25 136 0.5527 0.8821
112 hsa01040_Biosynthesis_of_unsaturated_fatty_acids 4 21 0.5636 0.8821
113 hsa02010_ABC_transporters 8 44 0.5848 0.9074
114 hsa03440_Homologous_recombination 5 28 0.6128 0.9428
115 hsa00740_Riboflavin_metabolism 2 11 0.6326 0.9537
116 hsa00450_Selenocompound_metabolism 3 17 0.6349 0.9537
117 hsa03060_Protein_export 4 23 0.6398 0.9537
118 hsa00350_Tyrosine_metabolism 7 41 0.6575 0.97
119 hsa00760_Nicotinate_and_nicotinamide_metabolism 4 24 0.6745 0.982
120 hsa00650_Butanoate_metabolism 5 30 0.6765 0.982
121 hsa00100_Steroid_biosynthesis 3 19 0.7116 1
122 hsa00260_Glycine._serine_and_threonine_metabolism 5 32 0.7327 1
123 hsa04145_Phagosome 26 156 0.7561 1
124 hsa00240_Pyrimidine_metabolism 16 99 0.7658 1
125 hsa00514_Other_types_of_O.glycan_biosynthesis 7 46 0.7739 1
126 hsa04140_Regulation_of_autophagy 5 34 0.7815 1
127 hsa03015_mRNA_surveillance_pathway 13 83 0.7897 1
128 hsa00900_Terpenoid_backbone_biosynthesis 2 15 0.7961 1
129 hsa00982_Drug_metabolism_._cytochrome_P450 11 73 0.8183 1
130 hsa00565_Ether_lipid_metabolism 5 36 0.8231 1
131 hsa00120_Primary_bile_acid_biosynthesis 2 16 0.8254 1
132 hsa03010_Ribosome 14 92 0.8295 1
133 hsa04977_Vitamin_digestion_and_absorption 3 24 0.8486 1
134 hsa04614_Renin.angiotensin_system 2 17 0.8508 1
135 hsa03320_PPAR_signaling_pathway 10 70 0.8591 1
136 hsa00980_Metabolism_of_xenobiotics_by_cytochrome_P450 10 71 0.8707 1
137 hsa03018_RNA_degradation 10 71 0.8707 1
138 hsa04622_RIG.I.like_receptor_signaling_pathway 10 71 0.8707 1
139 hsa04612_Antigen_processing_and_presentation 11 78 0.8785 1
140 hsa04966_Collecting_duct_acid_secretion 3 27 0.9001 1
141 hsa00592_alpha.Linolenic_acid_metabolism 2 20 0.908 1
142 hsa00860_Porphyrin_and_chlorophyll_metabolism 5 43 0.9209 1
143 hsa03020_RNA_polymerase 3 29 0.9251 1
144 hsa03050_Proteasome 5 45 0.9381 1
145 hsa03420_Nucleotide_excision_repair 5 45 0.9381 1
146 hsa00500_Starch_and_sucrose_metabolism 6 54 0.951 1
147 hsa03410_Base_excision_repair 3 34 0.9646 1
148 hsa00830_Retinol_metabolism 7 64 0.9653 1
149 hsa00053_Ascorbate_and_aldarate_metabolism 2 26 0.9665 1
150 hsa03030_DNA_replication 3 36 0.974 1
151 hsa04742_Taste_transduction 5 52 0.975 1
152 hsa04744_Phototransduction 2 29 0.9801 1
153 hsa00591_Linoleic_acid_metabolism 2 30 0.9833 1
154 hsa04623_Cytosolic_DNA.sensing_pathway 5 56 0.9856 1
155 hsa00140_Steroid_hormone_biosynthesis 5 57 0.9874 1
156 hsa00040_Pentose_and_glucuronate_interconversions 2 32 0.9883 1
157 hsa00590_Arachidonic_acid_metabolism 5 59 0.9905 1
158 hsa00983_Drug_metabolism_._other_enzymes 4 52 0.992 1
159 hsa03013_RNA_transport 17 152 0.9951 1
160 hsa03008_Ribosome_biogenesis_in_eukaryotes 7 81 0.996 1
161 hsa00970_Aminoacyl.tRNA_biosynthesis 4 63 0.9986 1
162 hsa04975_Fat_digestion_and_absorption 2 46 0.9991 1
163 hsa00190_Oxidative_phosphorylation 10 132 0.9999 1
164 hsa03040_Spliceosome 7 128 1 1
165 hsa04740_Olfactory_transduction 7 388 1 1

Quest ID: 9e04b45e2993ad1eb5cb02294bc3383f