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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-let-7a-5p ASPM -0.4 2.0E-5 1.15 0 miRNAWalker2 validate -0.39 3.0E-5 NA
2 hsa-miR-192-5p ASPM -0.47 0 1.15 0 miRNAWalker2 validate -0.41 5.0E-5 NA
3 hsa-miR-26b-5p ASPM -0.63 0 1.15 0 miRNAWalker2 validate -0.59 0 NA
4 hsa-let-7b-5p AURKA -0.75 0 -0.28 0.00642 miRNAWalker2 validate -0.12 0.00522 NA
5 hsa-miR-30c-2-3p AURKA -0.79 0 -0.28 0.00642 MirTarget -0.14 8.0E-5 NA
6 hsa-let-7b-5p BIRC5 -0.75 0 1.55 0 miRNAWalker2 validate -0.28 0.00247 NA
7 hsa-miR-186-5p BIRC5 -0.52 0 1.55 0 mirMAP -0.44 0.0022 NA
8 hsa-miR-218-5p BIRC5 -0.98 0 1.55 0 miRTarBase; MirTarget -0.2 0.01392 25473903; 25900794; 26442524 Survivin BIRC5 was subsequently identified as an important cervical cancer target of miR-218 using in silico prediction mRNA profiling and quantitative real-time PCR qRT-PCR;miR-218 binds survivin BIRC5 mRNA 3'-UTR and down-regulated reporter luciferase activity;MiR-218 promoted apoptosis inhibited cell proliferation and caused cell cycle arrest in CRC cells by suppressing BIRC5 expression; In conclusion we demonstrated that high miR-218 expression had a positive prognostic value in 5-FU-based treatments for CRC patients and discovered a novel mechanism mediated by miR-218 to promote apoptosis and to function synergistically with 5-FU to promote chemosensitivity by suppressing BIRC5 and TS in CRC
9 hsa-miR-30c-5p BIRC5 -0.63 0 1.55 0 miRNAWalker2 validate -0.7 0 NA
10 hsa-miR-335-5p BIRC5 -0.5 0 1.55 0 miRNAWalker2 validate; MirTarget -0.42 0 23232114 Genetic variation in a miR 335 binding site in BIRC5 alters susceptibility to lung cancer in Chinese Han populations; In support of the postulation that the 3' UTR SNP may directly affect miRNA-binding site reporter gene assays indicated BIRC5 was a direct target of miR-335 and the rs2239680 T>C change resulted in altered regulation of BIRC5 expression; Our findings defined a 3' UTR SNP in human BIRC5 oncogene that may increase individual susceptibility to lung cancer probably by attenuating the interaction between miR-335 and BIRC5
11 hsa-miR-338-3p BIRC5 -0.32 0.03679 1.55 0 miRanda -0.29 0 NA
12 hsa-miR-421 BIRC5 -0.4 0.00042 1.55 0 miRanda; mirMAP -0.26 0.00212 NA
13 hsa-miR-542-3p BIRC5 0.23 0.17581 1.55 0 miRNAWalker2 validate; MirTarget; miRanda -0.2 0.00035 NA
14 hsa-miR-139-5p BUB1 -1.02 0 1.76 0 miRanda -0.53 0 NA
15 hsa-miR-186-5p BUB1 -0.52 0 1.76 0 miRNAWalker2 validate -0.69 0 NA
16 hsa-miR-324-5p BUB1 -0 0.96822 1.76 0 MirTarget -0.34 0.0001 NA
17 hsa-miR-542-3p BUB1 0.23 0.17581 1.76 0 miRanda -0.29 0 NA
18 hsa-let-7b-3p CCNA2 -0.84 0 0.48 0.00052 MirTarget -0.21 0.00181 NA
19 hsa-miR-130a-3p CCNA2 -0.74 0 0.48 0.00052 miRNATAP -0.11 0.03288 NA
20 hsa-miR-22-3p CCNA2 -0.1 0.18413 0.48 0.00052 MirTarget -0.21 0.00888 25596928 The sequence of miR-22 which is conserved in mice rats humans and other mammalians aligns with the sequence of 3'-UTR of CCNA2; Chenodeoxycholic acid treatment and miR-22 mimics reduced CCNA2 protein and increased the number of G0/G1 Huh7 and HCT116 cells; In humans the expression levels of miR-22 and CCNA2 are inversely correlated in liver and colon cancers
21 hsa-miR-27b-3p CCNA2 0.27 0.00111 0.48 0.00052 miRNATAP -0.22 0.00144 NA
22 hsa-miR-374b-5p CCNA2 -0.76 0 0.48 0.00052 mirMAP -0.27 0.00051 NA
23 hsa-miR-486-5p CCNA2 -2.71 0 0.48 0.00052 miRanda -0.11 4.0E-5 NA
24 hsa-miR-98-5p CCNA2 -0.33 3.0E-5 0.48 0.00052 miRNAWalker2 validate -0.62 0 NA
25 hsa-let-7a-5p CCNB2 -0.4 2.0E-5 0.89 0 miRNAWalker2 validate -0.35 0 NA
26 hsa-let-7b-5p CCNB2 -0.75 0 0.89 0 miRNAWalker2 validate -0.16 0.00398 NA
27 hsa-let-7c-5p CCNB2 -0.7 0 0.89 0 miRNAWalker2 validate -0.4 0 NA
28 hsa-let-7f-5p CCNB2 -0.29 0.03106 0.89 0 miRNAWalker2 validate -0.22 0 NA
29 hsa-miR-23b-3p CCNB2 0.37 1.0E-5 0.89 0 miRNAWalker2 validate -0.32 0 NA
30 hsa-miR-192-5p DLGAP5 -0.47 0 1.72 0 miRNAWalker2 validate -0.48 1.0E-5 NA
31 hsa-miR-192-5p KIF20A -0.47 0 1.55 0 miRNAWalker2 validate -0.33 0.00054 NA
32 hsa-miR-374a-5p KIF20A -0.67 0 1.55 0 MirTarget -0.35 0.00381 NA
33 hsa-miR-374b-5p KIF20A -0.76 0 1.55 0 MirTarget -0.53 0 NA
34 hsa-miR-139-5p MAD2L1 -1.02 0 0.26 0.00598 miRanda -0.15 0 NA
35 hsa-miR-192-5p MAD2L1 -0.47 0 0.26 0.00598 miRNAWalker2 validate -0.14 0.00196 NA
36 hsa-miR-185-5p NCAPG -0.39 0 0.95 0 MirTarget -0.55 0 NA
37 hsa-miR-30e-3p NCAPG -0.64 0 0.95 0 mirMAP -0.39 0 NA
38 hsa-miR-374a-5p NCAPG -0.67 0 0.95 0 mirMAP -0.34 0.003 NA
39 hsa-miR-374b-5p NCAPG -0.76 0 0.95 0 mirMAP -0.46 1.0E-5 NA
40 hsa-miR-421 NCAPG -0.4 0.00042 0.95 0 miRNAWalker2 validate -0.22 0.00182 NA
41 hsa-miR-101-5p PBK -0.46 7.0E-5 1.48 0 MirTarget -0.22 0.00341 NA
42 hsa-miR-106a-5p PBK -1.01 0 1.48 0 MirTarget -0.25 0.00148 NA
43 hsa-miR-20b-5p PBK -1.56 0 1.48 0 MirTarget -0.18 5.0E-5 NA
44 hsa-miR-28-5p PBK -1 0 1.48 0 miRanda -0.28 0.01278 NA
45 hsa-let-7a-5p RRM2 -0.4 2.0E-5 1.38 0 miRNAWalker2 validate; TargetScan; miRNATAP -0.52 0 NA
46 hsa-let-7b-5p RRM2 -0.75 0 1.38 0 miRNAWalker2 validate; miRNATAP -0.31 0.00017 NA
47 hsa-let-7d-5p RRM2 -0.26 5.0E-5 1.38 0 miRNATAP -0.79 0 NA
48 hsa-let-7e-5p RRM2 0.46 1.0E-5 1.38 0 miRNATAP -0.3 0.00023 NA
49 hsa-let-7f-5p RRM2 -0.29 0.03106 1.38 0 miRNATAP -0.3 0 NA
50 hsa-let-7g-5p RRM2 -0.46 0 1.38 0 miRNAWalker2 validate; miRNATAP -0.43 0 NA
51 hsa-let-7i-5p RRM2 -0.1 0.26482 1.38 0 miRNATAP -0.22 0.01867 NA
52 hsa-miR-100-5p RRM2 -1.15 0 1.38 0 miRNAWalker2 validate -0.35 0 NA
53 hsa-miR-106a-5p RRM2 -1.01 0 1.38 0 miRNATAP -0.29 0.00029 NA
54 hsa-miR-125a-5p RRM2 0.45 0 1.38 0 miRanda -0.39 1.0E-5 NA
55 hsa-miR-186-5p RRM2 -0.52 0 1.38 0 miRNAWalker2 validate -0.45 0.00042 NA
56 hsa-miR-20b-5p RRM2 -1.56 0 1.38 0 miRNATAP -0.23 0 NA
57 hsa-miR-26a-5p RRM2 -0.78 0 1.38 0 miRNAWalker2 validate -0.27 0.02064 NA
58 hsa-miR-30a-5p RRM2 -0.74 0 1.38 0 miRNAWalker2 validate -0.95 0 NA
59 hsa-miR-30c-5p RRM2 -0.63 0 1.38 0 miRNAWalker2 validate -0.8 0 NA
60 hsa-miR-362-3p RRM2 -0.52 1.0E-5 1.38 0 miRanda -0.21 0.00479 NA
61 hsa-miR-421 RRM2 -0.4 0.00042 1.38 0 miRanda -0.23 0.00193 NA
62 hsa-miR-484 RRM2 -0.69 0 1.38 0 miRNAWalker2 validate -0.21 0.01426 NA
63 hsa-miR-139-5p TOP2A -1.02 0 1.46 0 miRanda -0.4 0 26079880 We identified that miR-139 a previous reported anti-metastatic microRNA targets 3'-untranslated region 3'UTR of TOP2a mRNA; Further more we revealed that the forced expression of miR-139 reduces the TOP2a expression at both mRNA and protein levels; And our functional experiments showed that the ectopic expression of miR-139 remarkably inhibits proliferation in luminal type breast cancer cells while exogenous TOP2a expression could rescue inhibition of cell proliferation mediated by miR-139
64 hsa-miR-186-5p TOP2A -0.52 0 1.46 0 miRNAWalker2 validate -0.41 0.00042 NA
65 hsa-miR-542-3p TOP2A 0.23 0.17581 1.46 0 miRanda -0.15 0.00081 NA
66 hsa-miR-7-5p TOP2A -3.13 0 1.46 0 miRNAWalker2 validate -0.2 0 NA
67 hsa-miR-491-5p TPX2 -0.49 0 1.43 0 miRanda -0.57 0 27053618; 26279431 miR 491 inhibits the proliferation invasion and migration of hepatocellular carcinoma cell via down regulating TPX2 expression; Overexpression of miR-491 in MHCC-97H cells markedly suppressed cell proliferation invasion and migration and downregulated the protein expression of TPX2; Correlation analysis showed that miR-491 level was negatively correlated with TPX2 expression level in HCC tissues; miR-491 inhibits HCC cell proliferation invasion and migration by downregulating the expression of TPX2;Low Expression of miR 491 Promotes Esophageal Cancer Cell Invasion by Targeting TPX2; The expression of miR-491 and candidate gene TPX2 in EC samples n=99 were detected by RT-PCR; Furthermore we verified that TPX2 was a target gene of miR-491 miR-491 may play a critical role in EC
68 hsa-miR-139-5p TTK -1.02 0 0.94 0 miRanda -0.21 0 NA
69 hsa-miR-192-5p TTK -0.47 0 0.94 0 miRNAWalker2 validate -0.22 0.00076 NA
70 hsa-miR-338-5p TTK -0.39 0.01026 0.94 0 PITA -0.19 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 MITOTIC CELL CYCLE 15 766 4.902e-22 2.281e-18
2 CELL CYCLE PROCESS 15 1081 8.95e-20 2.082e-16
3 CELL CYCLE 15 1316 1.741e-18 2.701e-15
4 ORGANELLE FISSION 12 496 2.019e-17 2.349e-14
5 MITOTIC NUCLEAR DIVISION 11 361 7.289e-17 6.783e-14
6 CELL DIVISION 11 460 1.064e-15 8.25e-13
7 REGULATION OF CELL CYCLE 11 949 2.974e-12 1.977e-09
8 REGULATION OF MITOTIC CELL CYCLE 9 468 8.613e-12 5.009e-09
9 CELL CYCLE CHECKPOINT 7 194 4.368e-11 2.258e-08
10 CHROMOSOME SEGREGATION 7 272 4.672e-10 1.864e-07
11 REGULATION OF CELL DIVISION 7 272 4.672e-10 1.864e-07
12 MITOTIC CELL CYCLE CHECKPOINT 6 139 4.806e-10 1.864e-07
13 REGULATION OF PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 6 148 7.026e-10 2.515e-07
14 REGULATION OF NUCLEAR DIVISION 6 163 1.259e-09 4.183e-07
15 REGULATION OF CELL CYCLE PHASE TRANSITION 7 321 1.481e-09 4.595e-07
16 SISTER CHROMATID SEGREGATION 6 176 1.998e-09 5.469e-07
17 REGULATION OF CELL CYCLE PROCESS 8 558 1.892e-09 5.469e-07
18 REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS 6 181 2.365e-09 6.114e-07
19 SPINDLE CHECKPOINT 4 25 2.567e-09 6.286e-07
20 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 6 199 4.18e-09 9.725e-07
21 NEGATIVE REGULATION OF ORGANELLE ORGANIZATION 7 387 5.418e-09 1.201e-06
22 NUCLEAR CHROMOSOME SEGREGATION 6 228 9.441e-09 1.997e-06
23 REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 6 274 2.825e-08 5.715e-06
24 MICROTUBULE BASED PROCESS 7 522 4.254e-08 8.248e-06
25 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 5 146 5.48e-08 1.02e-05
26 NEGATIVE REGULATION OF CELL DIVISION 4 60 9.744e-08 1.744e-05
27 MICROTUBULE CYTOSKELETON ORGANIZATION 6 348 1.166e-07 1.949e-05
28 NEGATIVE REGULATION OF PROTEIN COMPLEX DISASSEMBLY 5 170 1.173e-07 1.949e-05
29 NEGATIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 4 64 1.267e-07 2.033e-05
30 REGULATION OF MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION 5 178 1.475e-07 2.287e-05
31 REGULATION OF SISTER CHROMATID SEGREGATION 4 67 1.527e-07 2.292e-05
32 MITOTIC SPINDLE ORGANIZATION 4 69 1.721e-07 2.502e-05
33 SPINDLE ASSEMBLY 4 70 1.824e-07 2.572e-05
34 REGULATION OF PROTEIN CATABOLIC PROCESS 6 393 2.387e-07 3.267e-05
35 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 7 684 2.688e-07 3.574e-05
36 REGULATION OF PROTEOLYSIS 7 711 3.495e-07 4.517e-05
37 NEGATIVE REGULATION OF CELL CYCLE PROCESS 5 214 3.684e-07 4.633e-05
38 REGULATION OF CHROMOSOME SEGREGATION 4 85 4.002e-07 4.774e-05
39 REGULATION OF PROTEIN COMPLEX DISASSEMBLY 5 217 3.947e-07 4.774e-05
40 NEGATIVE REGULATION OF CYTOSKELETON ORGANIZATION 5 221 4.321e-07 4.904e-05
41 NEGATIVE REGULATION OF CELL CYCLE 6 433 4.219e-07 4.904e-05
42 REGULATION OF ORGANELLE ORGANIZATION 8 1178 6.276e-07 6.952e-05
43 REGULATION OF MICROTUBULE BASED PROCESS 5 243 6.909e-07 7.476e-05
44 CELL CYCLE PHASE TRANSITION 5 255 8.765e-07 9.269e-05
45 NEGATIVE REGULATION OF PROTEIN CATABOLIC PROCESS 4 109 1.088e-06 0.0001118
46 NEGATIVE REGULATION OF CHROMOSOME SEGREGATION 3 28 1.106e-06 0.0001118
47 POSITIVE REGULATION OF MITOTIC CELL CYCLE 4 123 1.764e-06 0.0001747
48 NEGATIVE REGULATION OF MITOTIC NUCLEAR DIVISION 3 34 2.014e-06 0.0001952
49 CELL CYCLE G2 M PHASE TRANSITION 4 138 2.792e-06 0.0002652
50 NEGATIVE REGULATION OF PROTEOLYSIS 5 329 3.065e-06 0.0002852
51 CHROMOSOME ORGANIZATION 7 1009 3.669e-06 0.0003348
52 NEGATIVE REGULATION OF CELLULAR CATABOLIC PROCESS 4 156 4.547e-06 0.0004068
53 NEGATIVE REGULATION OF NUCLEAR DIVISION 3 46 5.082e-06 0.0004461
54 POSITIVE REGULATION OF MITOTIC NUCLEAR DIVISION 3 51 6.956e-06 0.0005993
55 REGULATION OF CATABOLIC PROCESS 6 731 8.811e-06 0.0007454
56 POSITIVE REGULATION OF NUCLEAR DIVISION 3 62 1.257e-05 0.001044
57 NEGATIVE REGULATION OF CATABOLIC PROCESS 4 203 1.289e-05 0.001052
58 CYTOSKELETON ORGANIZATION 6 838 1.922e-05 0.001542
59 REGULATION OF CYTOSKELETON ORGANIZATION 5 502 2.381e-05 0.001878
60 POSITIVE REGULATION OF CELL CYCLE PROCESS 4 247 2.784e-05 0.002159
61 MITOTIC SISTER CHROMATID SEGREGATION 3 91 3.985e-05 0.00304
62 REGULATION OF CHROMOSOME ORGANIZATION 4 278 4.419e-05 0.003317
63 NEGATIVE REGULATION OF CHROMOSOME ORGANIZATION 3 96 4.676e-05 0.003454
64 MITOTIC DNA INTEGRITY CHECKPOINT 3 100 5.283e-05 0.003841
65 SISTER CHROMATID COHESION 3 111 7.211e-05 0.005162
66 CENTROSOME LOCALIZATION 2 18 7.977e-05 0.005624
67 POSITIVE REGULATION OF CELL CYCLE 4 332 8.808e-05 0.006117
68 CHROMOSOME SEPARATION 2 20 9.898e-05 0.006773
69 POSITIVE REGULATION OF CELL DIVISION 3 132 0.0001207 0.008136
NumGOOverlapSizeP ValueAdj. P Value
NumGOOverlapSizeP ValueAdj. P Value
1 MICROTUBULE CYTOSKELETON 11 1068 1.073e-11 3.133e-09
2 SPINDLE 8 289 1.017e-11 3.133e-09
3 CYTOSKELETAL PART 11 1436 2.628e-10 5.117e-08
4 CONDENSED CHROMOSOME 6 195 3.7e-09 5.403e-07
5 CYTOSKELETON 11 1967 7.614e-09 8.893e-07
6 SPINDLE POLE 5 126 2.616e-08 2.546e-06
7 CENTROSOME 6 487 8.394e-07 6.128e-05
8 CONDENSED CHROMOSOME CENTROMERIC REGION 4 102 8.336e-07 6.128e-05
9 MIDBODY 4 132 2.339e-06 0.0001518
10 MICROTUBULE ORGANIZING CENTER 6 623 3.511e-06 0.000205
11 CHROMOSOME CENTROMERIC REGION 4 174 7.01e-06 0.0003722
12 MITOTIC SPINDLE 3 55 8.747e-06 0.0003929
13 MICROTUBULE 5 405 8.439e-06 0.0003929
14 CHROMOSOME 6 880 2.537e-05 0.001058
15 CENTRIOLE 3 102 5.605e-05 0.002046
16 PRONUCLEUS 2 15 5.482e-05 0.002046
17 CONDENSED NUCLEAR CHROMOSOME CENTROMERIC REGION 2 18 7.977e-05 0.00274
18 CHROMOSOMAL REGION 4 330 8.604e-05 0.002756
19 KINETOCHORE 3 120 9.093e-05 0.002756
20 SUPRAMOLECULAR FIBER 5 670 9.438e-05 0.002756
21 MICROTUBULE ASSOCIATED COMPLEX 3 145 0.0001593 0.004229
22 MICROTUBULE ORGANIZING CENTER PART 3 145 0.0001593 0.004229

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Cell_cycle_hsa04110 5 124 2.414e-08 1.255e-06
2 Oocyte_meiosis_hsa04114 4 124 1.822e-06 4.738e-05
3 p53_signaling_pathway_hsa04115 2 68 0.001162 0.02015
4 Cellular_senescence_hsa04218 2 160 0.006237 0.08108

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1 CTA-384D8.35 hsa-let-7a-5p;hsa-let-7b-5p;hsa-let-7d-5p;hsa-let-7e-5p;hsa-let-7f-5p;hsa-let-7g-5p;hsa-miR-106a-5p;hsa-miR-125a-5p;hsa-miR-20b-5p;hsa-miR-30a-5p 10 RRM2 Sponge network 1.535 0 1.382 0 0.53
2 FOXD2-AS1 hsa-let-7a-5p;hsa-let-7b-5p;hsa-let-7d-5p;hsa-let-7f-5p;hsa-let-7g-5p;hsa-miR-100-5p;hsa-miR-106a-5p;hsa-miR-186-5p;hsa-miR-20b-5p;hsa-miR-26a-5p;hsa-miR-362-3p;hsa-miR-484 12 RRM2 Sponge network 1.419 0 1.382 0 0.5
3 HCP5 hsa-let-7a-5p;hsa-let-7b-5p;hsa-let-7d-5p;hsa-let-7e-5p;hsa-let-7f-5p;hsa-miR-106a-5p;hsa-miR-125a-5p;hsa-miR-186-5p;hsa-miR-20b-5p;hsa-miR-484 10 RRM2 Sponge network 0.448 0.01874 1.382 0 0.499
4 RP11-817J15.2 hsa-let-7a-5p;hsa-let-7b-5p;hsa-let-7d-5p;hsa-let-7f-5p;hsa-let-7g-5p;hsa-miR-106a-5p;hsa-miR-125a-5p;hsa-miR-186-5p;hsa-miR-20b-5p;hsa-miR-30a-5p;hsa-miR-421;hsa-miR-484 12 RRM2 Sponge network 3.031 4.0E-5 1.382 0 0.46
5 AC074289.1 hsa-let-7a-5p;hsa-let-7b-5p;hsa-let-7d-5p;hsa-let-7e-5p;hsa-let-7f-5p;hsa-let-7g-5p;hsa-miR-106a-5p;hsa-miR-125a-5p;hsa-miR-20b-5p;hsa-miR-30a-5p;hsa-miR-30c-5p 11 RRM2 Sponge network 0.438 0.01843 1.382 0 0.432
6 MIAT hsa-let-7d-5p;hsa-let-7e-5p;hsa-let-7g-5p;hsa-miR-106a-5p;hsa-miR-125a-5p;hsa-miR-186-5p;hsa-miR-20b-5p;hsa-miR-30a-5p;hsa-miR-421;hsa-miR-484 10 RRM2 Sponge network 0.272 0.2414 1.382 0 0.416
7 LINC00511 hsa-let-7a-5p;hsa-let-7b-5p;hsa-let-7d-5p;hsa-let-7f-5p;hsa-let-7g-5p;hsa-miR-106a-5p;hsa-miR-125a-5p;hsa-miR-186-5p;hsa-miR-20b-5p;hsa-miR-30a-5p;hsa-miR-30c-5p;hsa-miR-362-3p;hsa-miR-421;hsa-miR-484 14 RRM2 Sponge network 2.221 0 1.382 0 0.415
8 ITGB2-AS1 hsa-let-7a-5p;hsa-let-7b-5p;hsa-let-7d-5p;hsa-let-7e-5p;hsa-let-7f-5p;hsa-let-7g-5p;hsa-miR-106a-5p;hsa-miR-125a-5p;hsa-miR-186-5p;hsa-miR-20b-5p;hsa-miR-421 11 RRM2 Sponge network 0.719 0.10736 1.382 0 0.407
9 RP3-522D1.1 hsa-let-7a-5p;hsa-let-7b-5p;hsa-let-7d-5p;hsa-let-7f-5p;hsa-let-7g-5p;hsa-miR-100-5p;hsa-miR-106a-5p;hsa-miR-20b-5p;hsa-miR-26a-5p;hsa-miR-30a-5p 10 RRM2 Sponge network 2.642 0 1.382 0 0.38
10 LINC00607 hsa-let-7a-5p;hsa-let-7b-5p;hsa-let-7d-5p;hsa-let-7g-5p;hsa-miR-106a-5p;hsa-miR-186-5p;hsa-miR-20b-5p;hsa-miR-30a-5p;hsa-miR-362-3p;hsa-miR-421 10 RRM2 Sponge network 2.021 0 1.382 0 0.37
11 RP11-863P13.3 hsa-let-7a-5p;hsa-let-7d-5p;hsa-let-7e-5p;hsa-let-7f-5p;hsa-let-7g-5p;hsa-miR-106a-5p;hsa-miR-125a-5p;hsa-miR-186-5p;hsa-miR-20b-5p;hsa-miR-30a-5p;hsa-miR-484 11 RRM2 Sponge network 0.626 0.30009 1.382 0 0.332

Quest ID: 9f0ef8fdd5eeaa66c38569b0ccf98c5e