Visible node/edge number:
Node colors:
Node labels:

show label of nodes with degree >=

Node sizes:
Edge colors:
Edge widths factor:
Layout:

gravity >=

edgeLength =

GRN in network:

Notice: IE browser need to manually refresh (F5) this page after resetting the network.

This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-let-7c-5p GSK3A -1.71 0 0.35 0 miRNAWalker2 validate -0.1 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 INTRACELLULAR SIGNAL TRANSDUCTION 71 1572 6.789e-20 3.159e-16
2 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 76 1848 5.503e-19 8.534e-16
3 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 79 1977 4.851e-19 8.534e-16
4 RESPONSE TO ENDOGENOUS STIMULUS 64 1450 2.281e-17 2.122e-14
5 PROTEIN PHOSPHORYLATION 51 944 2.216e-17 2.122e-14
6 RESPONSE TO HORMONE 49 893 5.581e-17 3.694e-14
7 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 52 1008 7.145e-17 3.694e-14
8 PHOSPHORYLATION 58 1228 4.798e-17 3.694e-14
9 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 71 1784 6.551e-17 3.694e-14
10 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 71 1805 1.215e-16 5.655e-14
11 CELLULAR RESPONSE TO HORMONE STIMULUS 38 552 1.921e-16 8.127e-14
12 RESPONSE TO OXYGEN CONTAINING COMPOUND 59 1381 2.345e-15 9.091e-13
13 POSITIVE REGULATION OF GENE EXPRESSION 67 1733 2.659e-15 9.517e-13
14 REGULATION OF PHOSPHORUS METABOLIC PROCESS 64 1618 4.545e-15 1.511e-12
15 REGULATION OF CELL DEATH 60 1472 1.068e-14 3.313e-12
16 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 43 799 1.153e-14 3.354e-12
17 REGULATION OF PROTEIN MODIFICATION PROCESS 65 1710 1.737e-14 4.755e-12
18 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 47 1004 1.018e-13 2.632e-11
19 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 57 1492 8.567e-13 2.098e-10
20 REGULATION OF CELL PROLIFERATION 57 1496 9.561e-13 2.224e-10
21 RESPONSE TO NITROGEN COMPOUND 41 859 2.558e-12 5.668e-10
22 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 53 1360 3.015e-12 6.378e-10
23 NEGATIVE REGULATION OF CELL COMMUNICATION 48 1192 1.237e-11 2.502e-09
24 HOMEOSTATIC PROCESS 51 1337 1.844e-11 3.574e-09
25 REGULATION OF RESPONSE TO STRESS 53 1468 5.352e-11 9.962e-09
26 RESPONSE TO PEPTIDE 26 404 6.49e-11 1.122e-08
27 NEGATIVE REGULATION OF CELL DEATH 39 872 6.513e-11 1.122e-08
28 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 41 957 7.449e-11 1.204e-08
29 CELLULAR RESPONSE TO NITROGEN COMPOUND 29 505 7.506e-11 1.204e-08
30 REGULATION OF KINASE ACTIVITY 36 776 1.406e-10 2.181e-08
31 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 35 740 1.548e-10 2.323e-08
32 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 56 1656 1.669e-10 2.426e-08
33 REGULATION OF TRANSFERASE ACTIVITY 40 946 1.932e-10 2.724e-08
34 CELLULAR RESPONSE TO PEPTIDE 21 274 2.033e-10 2.783e-08
35 REGULATION OF LIPID METABOLIC PROCESS 21 282 3.454e-10 4.592e-08
36 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 33 689 3.943e-10 5.096e-08
37 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 52 1517 5.385e-10 6.772e-08
38 CARDIOVASCULAR SYSTEM DEVELOPMENT 35 788 8.264e-10 9.859e-08
39 CIRCULATORY SYSTEM DEVELOPMENT 35 788 8.264e-10 9.859e-08
40 POSITIVE REGULATION OF RESPONSE TO STIMULUS 60 1929 8.642e-10 1.005e-07
41 NEGATIVE REGULATION OF GENE EXPRESSION 51 1493 9.21e-10 1.045e-07
42 PHOSPHATIDYLINOSITOL 3 PHOSPHATE BIOSYNTHETIC PROCESS 10 49 9.796e-10 1.085e-07
43 TISSUE DEVELOPMENT 51 1518 1.626e-09 1.76e-07
44 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 54 1672 1.986e-09 2.1e-07
45 REGULATION OF IMMUNE SYSTEM PROCESS 48 1403 3.007e-09 3.11e-07
46 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 42 1135 3.596e-09 3.638e-07
47 CELLULAR RESPONSE TO LIPID 25 457 4.394e-09 4.35e-07
48 NEGATIVE REGULATION OF CELL PROLIFERATION 30 643 4.816e-09 4.669e-07
49 RESPONSE TO LIPID 36 888 5.24e-09 4.976e-07
50 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 26 498 5.597e-09 5.208e-07
51 REGULATION OF CELLULAR COMPONENT BIOGENESIS 33 767 5.758e-09 5.253e-07
52 REGULATION OF CATABOLIC PROCESS 32 731 6.623e-09 5.926e-07
53 CELLULAR COMPONENT MORPHOGENESIS 36 900 7.429e-09 6.522e-07
54 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 39 1036 8.785e-09 7.432e-07
55 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 39 1036 8.785e-09 7.432e-07
56 LIPID PHOSPHORYLATION 12 99 1.059e-08 8.797e-07
57 INOSITOL LIPID MEDIATED SIGNALING 13 124 1.529e-08 1.249e-06
58 PEPTIDYL SERINE MODIFICATION 14 148 1.61e-08 1.291e-06
59 LOCOMOTION 40 1114 2.05e-08 1.616e-06
60 POSITIVE REGULATION OF MOLECULAR FUNCTION 54 1791 2.144e-08 1.635e-06
61 REGULATION OF CELL DIFFERENTIATION 48 1492 2.116e-08 1.635e-06
62 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 37 983 2.22e-08 1.666e-06
63 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 24 465 2.768e-08 2.044e-06
64 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 24 470 3.389e-08 2.464e-06
65 IMMUNE SYSTEM PROCESS 57 1984 4.314e-08 3.088e-06
66 PROTEIN DEPHOSPHORYLATION 15 190 5.658e-08 3.989e-06
67 REGULATION OF CELL ACTIVATION 24 484 5.884e-08 4.086e-06
68 POSITIVE REGULATION OF CELL DEATH 27 605 7.381e-08 5.051e-06
69 GLUCOSE HOMEOSTASIS 14 170 9.332e-08 6.203e-06
70 CARBOHYDRATE HOMEOSTASIS 14 170 9.332e-08 6.203e-06
71 REGULATION OF CELLULAR KETONE METABOLIC PROCESS 14 173 1.161e-07 7.608e-06
72 RESPONSE TO ORGANIC CYCLIC COMPOUND 34 917 1.251e-07 8.086e-06
73 WOUND HEALING 23 470 1.423e-07 9.07e-06
74 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 12 126 1.609e-07 1.012e-05
75 REGULATION OF HYDROLASE ACTIVITY 42 1327 2.887e-07 1.789e-05
76 CELL DEVELOPMENT 44 1426 2.923e-07 1.789e-05
77 NEGATIVE REGULATION OF KINASE ACTIVITY 16 250 3.682e-07 2.225e-05
78 RESPONSE TO STEROID HORMONE 23 497 3.814e-07 2.269e-05
79 NEGATIVE REGULATION OF PHOSPHORYLATION 21 422 3.853e-07 2.269e-05
80 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 38 1152 4.167e-07 2.406e-05
81 PROTEIN AUTOPHOSPHORYLATION 14 192 4.188e-07 2.406e-05
82 PHOSPHATIDYLINOSITOL METABOLIC PROCESS 14 193 4.461e-07 2.531e-05
83 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 33 926 4.779e-07 2.679e-05
84 GLYCEROLIPID METABOLIC PROCESS 19 356 4.91e-07 2.72e-05
85 PEPTIDYL AMINO ACID MODIFICATION 31 841 5.351e-07 2.929e-05
86 VASCULATURE DEVELOPMENT 22 469 5.498e-07 2.975e-05
87 ENERGY RESERVE METABOLIC PROCESS 9 72 5.791e-07 3.097e-05
88 NEGATIVE REGULATION OF CELL CYCLE 21 433 5.86e-07 3.099e-05
89 POSITIVE REGULATION OF CATALYTIC ACTIVITY 45 1518 6.405e-07 3.348e-05
90 BLOOD VESSEL MORPHOGENESIS 19 364 6.868e-07 3.551e-05
91 EPIDERMAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 8 55 7.601e-07 3.887e-05
92 PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROCESS 11 120 7.815e-07 3.952e-05
93 REGULATION OF CELL CYCLE 33 949 8.246e-07 4.126e-05
94 REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 10 97 8.433e-07 4.174e-05
95 RESPONSE TO INSULIN 14 205 9.236e-07 4.488e-05
96 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 37 1142 9.26e-07 4.488e-05
97 CELL DEATH 34 1001 9.41e-07 4.514e-05
98 REGULATION OF CELLULAR RESPONSE TO STRESS 27 691 1.011e-06 4.802e-05
99 REGULATION OF PROTEIN COMPLEX ASSEMBLY 19 375 1.073e-06 5.041e-05
100 CELLULAR GLUCAN METABOLIC PROCESS 8 58 1.155e-06 5.321e-05
101 GLUCAN METABOLIC PROCESS 8 58 1.155e-06 5.321e-05
102 CHEMICAL HOMEOSTASIS 31 874 1.208e-06 5.511e-05
103 REGULATION OF MAPK CASCADE 26 660 1.395e-06 6.302e-05
104 INSULIN RECEPTOR SIGNALING PATHWAY 9 80 1.435e-06 6.419e-05
105 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 23 541 1.638e-06 7.191e-05
106 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 23 541 1.638e-06 7.191e-05
107 HORMONE MEDIATED SIGNALING PATHWAY 12 158 1.849e-06 7.967e-05
108 NEGATIVE REGULATION OF MOLECULAR FUNCTION 35 1079 1.833e-06 7.967e-05
109 REGULATION OF BODY FLUID LEVELS 22 506 1.932e-06 8.025e-05
110 HEART DEVELOPMENT 21 466 1.899e-06 8.025e-05
111 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 14 218 1.918e-06 8.025e-05
112 REGULATION OF CELL ADHESION 25 629 1.918e-06 8.025e-05
113 RESPONSE TO ACID CHEMICAL 17 319 2.027e-06 8.346e-05
114 REGULATION OF PROTEIN CATABOLIC PROCESS 19 393 2.145e-06 8.661e-05
115 DEPHOSPHORYLATION 16 286 2.178e-06 8.661e-05
116 REGULATION OF NEURON DEATH 15 252 2.123e-06 8.661e-05
117 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 35 1087 2.164e-06 8.661e-05
118 REGULATION OF CELLULAR PROTEIN LOCALIZATION 23 552 2.298e-06 9.062e-05
119 CELL PROJECTION ORGANIZATION 31 902 2.325e-06 9.091e-05
120 POSITIVE REGULATION OF CELL PROLIFERATION 29 814 2.507e-06 9.721e-05
121 RESPONSE TO GROWTH FACTOR 21 475 2.565e-06 9.863e-05
122 PEPTIDYL THREONINE MODIFICATION 7 46 2.776e-06 0.0001059
123 RESPONSE TO INORGANIC SUBSTANCE 21 479 2.924e-06 0.0001097
124 REGULATION OF FATTY ACID METABOLIC PROCESS 9 87 2.92e-06 0.0001097
125 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 30 867 2.992e-06 0.0001114
126 NEUROGENESIS 41 1402 3.048e-06 0.0001126
127 RESPONSE TO EXTERNAL STIMULUS 49 1821 3.077e-06 0.0001127
128 RESPONSE TO WOUNDING 23 563 3.193e-06 0.0001161
129 RESPONSE TO CARBOHYDRATE 12 168 3.514e-06 0.0001259
130 CELLULAR RESPONSE TO STRESS 44 1565 3.519e-06 0.0001259
131 CELL ACTIVATION 23 568 3.697e-06 0.0001313
132 REGULATION OF RESPONSE TO EXTRACELLULAR STIMULUS 12 171 4.221e-06 0.0001477
133 REGULATION OF RESPONSE TO NUTRIENT LEVELS 12 171 4.221e-06 0.0001477
134 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 24 616 4.362e-06 0.0001515
135 TISSUE MORPHOGENESIS 22 533 4.467e-06 0.0001539
136 CELLULAR RESPONSE TO INSULIN STIMULUS 11 146 5.39e-06 0.0001836
137 MULTICELLULAR ORGANISMAL HOMEOSTASIS 15 272 5.405e-06 0.0001836
138 EMBRYO DEVELOPMENT 30 894 5.492e-06 0.0001852
139 REGULATION OF PROTEIN LOCALIZATION 31 950 6.65e-06 0.0002226
140 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 17 351 7.259e-06 0.0002413
141 REGULATION OF CELLULAR COMPONENT MOVEMENT 27 771 7.762e-06 0.0002562
142 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 21 513 8.401e-06 0.0002753
143 CELL CYCLE ARREST 11 154 8.987e-06 0.0002909
144 POSITIVE REGULATION OF CATABOLIC PROCESS 18 395 9.002e-06 0.0002909
145 REGULATION OF EPITHELIAL CELL PROLIFERATION 15 285 9.469e-06 0.0003018
146 CELL JUNCTION ORGANIZATION 12 185 9.453e-06 0.0003018
147 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 23 602 9.543e-06 0.0003021
148 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 29 876 1.027e-05 0.000323
149 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 32 1021 1.06e-05 0.0003312
150 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 13 220 1.104e-05 0.0003423
151 REGULATION OF DEVELOPMENTAL GROWTH 15 289 1.118e-05 0.0003443
152 RESPONSE TO ABIOTIC STIMULUS 32 1024 1.125e-05 0.0003443
153 CELL MOTILITY 28 835 1.166e-05 0.0003522
154 LOCALIZATION OF CELL 28 835 1.166e-05 0.0003522
155 REGULATION OF CELLULAR LOCALIZATION 37 1277 1.204e-05 0.0003616
156 ERBB SIGNALING PATHWAY 8 79 1.228e-05 0.0003662
157 NONMOTILE PRIMARY CILIUM ASSEMBLY 5 23 1.257e-05 0.0003725
158 POLYSACCHARIDE METABOLIC PROCESS 8 80 1.348e-05 0.0003971
159 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 23 616 1.379e-05 0.0004034
160 PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 10 134 1.571e-05 0.0004541
161 NEGATIVE REGULATION OF STEROID METABOLIC PROCESS 5 24 1.57e-05 0.0004541
162 POSITIVE REGULATION OF PROTEIN CATABOLIC PROCESS 14 263 1.657e-05 0.000473
163 CELLULAR RESPONSE TO ABIOTIC STIMULUS 14 263 1.657e-05 0.000473
164 REPRODUCTION 37 1297 1.694e-05 0.0004806
165 EMBRYONIC MORPHOGENESIS 21 539 1.763e-05 0.0004973
166 NEGATIVE REGULATION OF MYELOID CELL DIFFERENTIATION 8 84 1.935e-05 0.0005423
167 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 10 138 2.031e-05 0.0005659
168 REGULATION OF GROWTH 23 633 2.119e-05 0.000587
169 REGULATION OF HOMOTYPIC CELL CELL ADHESION 15 307 2.273e-05 0.0006259
170 TISSUE HOMEOSTASIS 11 171 2.407e-05 0.0006588
171 POSITIVE REGULATION OF CELL COMMUNICATION 41 1532 2.535e-05 0.0006704
172 REGULATION OF WNT SIGNALING PATHWAY 15 310 2.545e-05 0.0006704
173 TUBE DEVELOPMENT 21 552 2.506e-05 0.0006704
174 POSITIVE REGULATION OF GROWTH 13 238 2.538e-05 0.0006704
175 TISSUE REMODELING 8 87 2.503e-05 0.0006704
176 REGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS 8 87 2.503e-05 0.0006704
177 CENTRAL NERVOUS SYSTEM DEVELOPMENT 28 872 2.55e-05 0.0006704
178 HEMOSTASIS 15 311 2.642e-05 0.0006906
179 FC RECEPTOR SIGNALING PATHWAY 12 206 2.77e-05 0.0007202
180 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 27 829 2.803e-05 0.0007246
181 REGULATION OF HEMOPOIESIS 15 314 2.952e-05 0.0007588
182 REGULATION OF MULTICELLULAR ORGANISM GROWTH 7 66 3.202e-05 0.0008141
183 ACTIVATION OF PROTEIN KINASE ACTIVITY 14 279 3.186e-05 0.0008141
184 CELLULAR MACROMOLECULE LOCALIZATION 35 1234 3.298e-05 0.0008339
185 LIPID MODIFICATION 12 210 3.347e-05 0.0008418
186 REGULATION OF FATTY ACID OXIDATION 5 28 3.471e-05 0.0008684
187 GLYCEROLIPID BIOSYNTHETIC PROCESS 12 211 3.506e-05 0.0008724
188 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 38 1395 3.554e-05 0.0008797
189 ORGAN MORPHOGENESIS 27 841 3.592e-05 0.0008843
190 HEART MORPHOGENESIS 12 212 3.672e-05 0.0008993
191 REGULATION OF CYTOPLASMIC TRANSPORT 19 481 3.703e-05 0.0009021
192 GLUCOSE METABOLIC PROCESS 9 119 3.768e-05 0.0009132
193 POSITIVE REGULATION OF KINASE ACTIVITY 19 482 3.808e-05 0.0009181
194 ORGAN GROWTH 7 68 3.894e-05 0.000934
195 REGULATION OF AUTOPHAGY 13 249 4.059e-05 0.0009685
196 IMMUNE RESPONSE REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 15 323 4.083e-05 0.0009692
197 RESPONSE TO ALCOHOL 16 362 4.111e-05 0.0009709
198 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 26 801 4.199e-05 0.0009868
199 IMMUNE EFFECTOR PROCESS 19 486 4.257e-05 0.0009953
200 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 17 404 4.384e-05 0.00102
201 REGULATION OF MYELOID CELL DIFFERENTIATION 11 183 4.493e-05 0.00104
202 ENERGY DERIVATION BY OXIDATION OF ORGANIC COMPOUNDS 12 217 4.608e-05 0.001061
203 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 6 48 4.644e-05 0.001064
204 CIRCULATORY SYSTEM PROCESS 16 366 4.686e-05 0.001065
205 REGULATION OF INTRACELLULAR TRANSPORT 22 621 4.69e-05 0.001065
206 PROTEIN CATABOLIC PROCESS 21 579 5.005e-05 0.00113
207 ORGANOPHOSPHATE BIOSYNTHETIC PROCESS 18 450 5.055e-05 0.001136
208 MULTICELLULAR ORGANISM REPRODUCTION 25 768 5.663e-05 0.001267
209 REGULATION OF PLATELET ACTIVATION 5 31 5.804e-05 0.001292
210 LEUKOCYTE ACTIVATION 17 414 5.933e-05 0.001308
211 REGULATION OF WOUND HEALING 9 126 5.905e-05 0.001308
212 CELL PART MORPHOGENESIS 22 633 6.218e-05 0.001365
213 GLYCEROPHOSPHOLIPID METABOLIC PROCESS 14 297 6.275e-05 0.001371
214 NEGATIVE REGULATION OF TRANSPORT 18 458 6.337e-05 0.001378
215 RHYTHMIC PROCESS 14 298 6.505e-05 0.001408
216 RESPONSE TO REACTIVE OXYGEN SPECIES 11 191 6.623e-05 0.001427
217 REGULATION OF LIPID BIOSYNTHETIC PROCESS 9 128 6.676e-05 0.001432
218 NEGATIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 5 32 6.803e-05 0.001452
219 NEURON DIFFERENTIATION 27 874 6.9e-05 0.001466
220 POSITIVE REGULATION OF LOCOMOTION 17 420 7.078e-05 0.001497
221 REGULATION OF CELL CELL ADHESION 16 380 7.298e-05 0.001537
222 LYMPHOCYTE ACTIVATION 15 342 7.787e-05 0.001632
223 SEX DIFFERENTIATION 13 266 7.966e-05 0.001662
224 REGULATION OF NITRIC OXIDE BIOSYNTHETIC PROCESS 6 53 8.206e-05 0.001705
225 REGULATION OF MITOTIC CELL CYCLE 18 468 8.338e-05 0.001724
226 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 8 103 8.443e-05 0.001738
227 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 11 197 8.741e-05 0.001784
228 POSITIVE REGULATION OF PROTEIN COMPLEX ASSEMBLY 11 197 8.741e-05 0.001784
229 DEFENSE RESPONSE TO VIRUS 10 164 8.837e-05 0.001796
230 CELLULAR RESPONSE TO REACTIVE OXYGEN SPECIES 8 104 9.04e-05 0.001829
231 REGULATION OF ANATOMICAL STRUCTURE SIZE 18 472 9.283e-05 0.00187
232 CEREBRAL CORTEX DEVELOPMENT 8 105 9.672e-05 0.001935
233 RESPONSE TO DRUG 17 431 9.692e-05 0.001935
234 EPITHELIUM DEVELOPMENT 28 945 0.0001029 0.002013
235 REGULATION OF FAT CELL DIFFERENTIATION 8 106 0.0001034 0.002013
236 POSITIVE REGULATION OF CELL ACTIVATION 14 311 0.0001024 0.002013
237 REGULATION OF GLUCOSE METABOLIC PROCESS 8 106 0.0001034 0.002013
238 CRANIAL SKELETAL SYSTEM DEVELOPMENT 6 55 0.0001013 0.002013
239 FAT CELL DIFFERENTIATION 8 106 0.0001034 0.002013
240 WNT SIGNALING PATHWAY 15 351 0.0001039 0.002015
241 REGULATION OF FATTY ACID BIOSYNTHETIC PROCESS 5 35 0.0001061 0.002048
242 RESPONSE TO OXIDATIVE STRESS 15 352 0.0001073 0.002062
243 INTRACELLULAR RECEPTOR SIGNALING PATHWAY 10 168 0.000108 0.002067
244 NEGATIVE REGULATION OF LIPID METABOLIC PROCESS 7 80 0.000111 0.002118
245 DRUG TRANSMEMBRANE TRANSPORT 4 19 0.000112 0.002118
246 REGULATION OF MICROTUBULE BASED MOVEMENT 4 19 0.000112 0.002118
247 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 17 437 0.0001145 0.002157
248 CELL CYCLE 35 1316 0.0001193 0.002238
249 POSITIVE REGULATION OF GLUCOSE METABOLIC PROCESS 5 36 0.0001218 0.002276
250 REGULATION OF CHROMOSOME ORGANIZATION 13 278 0.0001239 0.002298
251 REGULATION OF PROTEOLYSIS 23 711 0.0001239 0.002298
252 NEGATIVE REGULATION OF NEURON DEATH 10 171 0.000125 0.002307
253 RESPONSE TO HYDROGEN PEROXIDE 8 109 0.0001258 0.002313
254 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 20 573 0.0001271 0.002329
255 REGULATION OF CARBOHYDRATE METABOLIC PROCESS 10 172 0.0001311 0.002392
256 MORPHOGENESIS OF AN EPITHELIUM 16 400 0.0001322 0.002403
257 HOMEOSTASIS OF NUMBER OF CELLS 10 175 0.0001511 0.002735
258 CELLULAR COMPONENT ASSEMBLY INVOLVED IN MORPHOGENESIS 12 246 0.0001521 0.002742
259 IMMUNE SYSTEM DEVELOPMENT 20 582 0.0001564 0.002805
260 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 16 406 0.0001567 0.002805
261 ANATOMICAL STRUCTURE HOMEOSTASIS 13 285 0.0001585 0.002826
262 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 23 724 0.0001615 0.002867
263 POSITIVE REGULATION OF CHROMATIN MODIFICATION 7 85 0.0001628 0.002872
264 REGULATION OF ORGANELLE ORGANIZATION 32 1178 0.000163 0.002872
265 REGULATION OF GLUCOSE IMPORT 6 60 0.0001652 0.002891
266 CELLULAR CARBOHYDRATE METABOLIC PROCESS 9 144 0.0001648 0.002891
267 POSITIVE REGULATION OF CELL DIFFERENTIATION 25 823 0.0001675 0.00292
268 NOTCH SIGNALING PATHWAY 8 114 0.0001718 0.002983
269 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 7 86 0.0001752 0.00302
270 GROWTH 16 410 0.0001752 0.00302
271 MACROMOLECULE CATABOLIC PROCESS 27 926 0.0001782 0.00306
272 PEPTIDYL TYROSINE AUTOPHOSPHORYLATION 5 39 0.0001799 0.003078
273 CELLULAR RESPONSE TO HYDROGEN PEROXIDE 6 61 0.0001812 0.003088
274 CELL CYCLE PROCESS 30 1081 0.000183 0.003108
275 SKELETAL SYSTEM DEVELOPMENT 17 455 0.000185 0.003131
276 NEURON PROJECTION DEVELOPMENT 19 545 0.0001903 0.003208
277 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 9 147 0.0001925 0.003234
278 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 15 372 0.0001961 0.003282
279 NEURON DEVELOPMENT 22 687 0.0002007 0.003347
280 REGULATION OF COAGULATION 7 88 0.0002023 0.003362
281 NEGATIVE REGULATION OF MUSCLE CONTRACTION 4 22 0.0002046 0.003389
282 DEVELOPMENTAL GROWTH 14 333 0.0002085 0.003441
283 RESPONSE TO ESTROGEN 11 218 0.0002131 0.003503
284 POSITIVE REGULATION OF CELL ADHESION 15 376 0.00022 0.003604
285 REGULATION OF TRANSPORT 43 1804 0.0002229 0.003639
286 POSITIVE REGULATION OF CHROMOSOME ORGANIZATION 9 150 0.000224 0.003645
287 CELLULAR RESPONSE TO OXIDATIVE STRESS 10 184 0.0002271 0.003682
288 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 9 152 0.0002473 0.003975
289 REGULATION OF CHROMATIN ORGANIZATION 9 152 0.0002473 0.003975
290 PEPTIDYL TYROSINE MODIFICATION 10 186 0.0002478 0.003975
291 UROGENITAL SYSTEM DEVELOPMENT 13 299 0.0002531 0.004047
292 REGULATION OF CELL PROJECTION ORGANIZATION 19 558 0.0002561 0.004076
293 REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 6 65 0.0002576 0.004076
294 GENITALIA DEVELOPMENT 5 42 0.0002571 0.004076
295 NEGATIVE REGULATION OF CELL DIFFERENTIATION 20 609 0.000283 0.004463
296 POSITIVE REGULATION OF HYDROLASE ACTIVITY 26 905 0.0002958 0.00465
297 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 9 156 0.0002999 0.004699
298 POSITIVE REGULATION OF NEURON DEATH 6 67 0.0003042 0.00475
299 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 33 1275 0.0003095 0.004812
300 HEAD DEVELOPMENT 22 709 0.0003103 0.004812
301 REGULATION OF IMMUNE RESPONSE 25 858 0.0003143 0.004845
302 HEXOSE METABOLIC PROCESS 9 157 0.0003144 0.004845
303 REGULATION OF NEURON APOPTOTIC PROCESS 10 192 0.0003194 0.004906
304 NEGATIVE REGULATION OF LIPID BIOSYNTHETIC PROCESS 5 44 0.000321 0.004913
305 STEROID HORMONE MEDIATED SIGNALING PATHWAY 8 125 0.0003229 0.004926
306 RESPONSE TO TYPE I INTERFERON 6 68 0.0003299 0.005016
307 CELLULAR RESPONSE TO EPIDERMAL GROWTH FACTOR STIMULUS 4 25 0.0003427 0.005111
308 GLYCOGEN BIOSYNTHETIC PROCESS 4 25 0.0003427 0.005111
309 EPITHELIAL CELL APOPTOTIC PROCESS 4 25 0.0003427 0.005111
310 DRUG TRANSPORT 4 25 0.0003427 0.005111
311 GLUCAN BIOSYNTHETIC PROCESS 4 25 0.0003427 0.005111
312 PEPTIDE CATABOLIC PROCESS 4 25 0.0003427 0.005111
313 REGULATION OF JNK CASCADE 9 159 0.0003452 0.005132
314 CONNECTIVE TISSUE DEVELOPMENT 10 194 0.0003469 0.00514
315 REGULATION OF LEUKOCYTE DIFFERENTIATION 11 232 0.0003632 0.005365
316 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 14 352 0.000366 0.00539
317 NEGATIVE REGULATION OF HEMOPOIESIS 8 128 0.000379 0.005563
318 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 10 197 0.0003917 0.005731
319 CELL JUNCTION ASSEMBLY 8 129 0.0003993 0.005825
320 PHOSPHOLIPID BIOSYNTHETIC PROCESS 11 235 0.0004049 0.005887
321 INTRACELLULAR STEROID HORMONE RECEPTOR SIGNALING PATHWAY 6 71 0.0004172 0.006028
322 ADHERENS JUNCTION ORGANIZATION 6 71 0.0004172 0.006028
323 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 11 236 0.0004196 0.006045
324 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 10 199 0.0004242 0.006092
325 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 7 100 0.0004441 0.006358
326 PROTEIN LOCALIZATION TO CILIUM 4 27 0.0004653 0.006629
327 B CELL ACTIVATION 8 132 0.0004658 0.006629
328 REGULATION OF EPITHELIAL CELL MIGRATION 9 166 0.0004731 0.006712
329 NEGATIVE REGULATION OF COAGULATION 5 48 0.0004842 0.006835
330 REGULATION OF ORGAN GROWTH 6 73 0.0004847 0.006835
331 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 8 133 0.0004899 0.006887
332 ORGANOPHOSPHATE METABOLIC PROCESS 25 885 0.0004958 0.006949
333 REGULATION OF T CELL TOLERANCE INDUCTION 3 12 0.0005051 0.007037
334 RESPONSE TO BIOTIC STIMULUS 25 886 0.000504 0.007037
335 PHOSPHOLIPID METABOLIC PROCESS 14 364 0.0005108 0.007095
336 REGULATION OF PROTEIN BINDING 9 168 0.0005161 0.007147
337 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 6 74 0.0005215 0.007158
338 REPRODUCTIVE SYSTEM DEVELOPMENT 15 408 0.0005202 0.007158
339 REGULATION OF STEROID METABOLIC PROCESS 6 74 0.0005215 0.007158
340 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 12 282 0.0005268 0.007171
341 REGULATION OF MUSCLE TISSUE DEVELOPMENT 7 103 0.000531 0.007171
342 REGULATION OF NITRIC OXIDE SYNTHASE ACTIVITY 5 49 0.0005332 0.007171
343 REGULATION OF STEROID BIOSYNTHETIC PROCESS 5 49 0.0005332 0.007171
344 TUBE MORPHOGENESIS 13 323 0.0005279 0.007171
345 REGULATION OF MUSCLE ORGAN DEVELOPMENT 7 103 0.000531 0.007171
346 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 14 365 0.0005248 0.007171
347 CELL FATE COMMITMENT INVOLVED IN FORMATION OF PRIMARY GERM LAYER 4 28 0.0005371 0.007202
348 REGULATION OF LEUKOCYTE PROLIFERATION 10 206 0.000556 0.007434
349 CELLULAR GLUCOSE HOMEOSTASIS 6 75 0.0005605 0.007473
350 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 14 368 0.0005689 0.007562
351 LIPID METABOLIC PROCESS 30 1158 0.000579 0.007675
352 CELLULAR RESPONSE TO RADIATION 8 137 0.0005964 0.007884
353 RESPONSE TO VIRUS 11 247 0.000614 0.008094
354 MUSCLE ADAPTATION 4 29 0.0006164 0.008102
355 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 10 209 0.0006221 0.008154
356 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 18 554 0.0006431 0.008381
357 CELLULAR CARBOHYDRATE BIOSYNTHETIC PROCESS 5 51 0.0006425 0.008381
358 POSITIVE REGULATION OF GLUCONEOGENESIS 3 13 0.0006501 0.008449
359 POSITIVE REGULATION OF CELL CYCLE 13 332 0.0006818 0.008836
360 GLIOGENESIS 9 175 0.0006924 0.008949
361 RESPONSE TO EPIDERMAL GROWTH FACTOR 4 30 0.0007037 0.00902
362 RESPONSE TO METAL ION 13 333 0.000701 0.00902
363 REGULATION OF LIPID CATABOLIC PROCESS 5 52 0.000703 0.00902
364 GENERATION OF PRECURSOR METABOLITES AND ENERGY 12 292 0.0007159 0.009151
365 DENDRITE DEVELOPMENT 6 79 0.0007394 0.009401
366 ANGIOGENESIS 12 293 0.0007376 0.009401
367 PLATELET ACTIVATION 8 142 0.0007552 0.009548
368 FC EPSILON RECEPTOR SIGNALING PATHWAY 8 142 0.0007552 0.009548
369 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 5 53 0.0007677 0.00968
370 REGULATION OF DEFENSE RESPONSE 22 759 0.0007719 0.009707
371 CELLULAR LIPID METABOLIC PROCESS 25 913 0.0007756 0.009728
372 REGULATION OF BLOOD CIRCULATION 12 295 0.0007826 0.009763
373 REGULATION OF OSSIFICATION 9 178 0.0007817 0.009763
374 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 14 381 0.0007976 0.009924
NumGOOverlapSizeP ValueAdj. P Value
1 RIBONUCLEOTIDE BINDING 76 1860 7.995e-19 7.428e-16
2 ADENYL NUCLEOTIDE BINDING 67 1514 2.888e-18 1.341e-15
3 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 53 992 7.569e-18 2.344e-15
4 KINASE ACTIVITY 47 842 1.375e-16 3.192e-14
5 PROTEIN KINASE ACTIVITY 40 640 7.757e-16 1.441e-13
6 PROTEIN SERINE THREONINE KINASE ACTIVITY 32 445 1.65e-14 2.555e-12
7 ENZYME BINDING 65 1737 3.626e-14 4.812e-12
8 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 51 1199 3.15e-13 3.658e-11
9 REGULATORY REGION NUCLEIC ACID BINDING 37 818 1.55e-10 1.599e-08
10 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 31 629 7.04e-10 6.54e-08
11 KINASE BINDING 30 606 1.219e-09 1.03e-07
12 RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 13 104 1.738e-09 1.346e-07
13 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 11 70 2.66e-09 1.901e-07
14 X1 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 9 43 5.42e-09 3.357e-07
15 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 21 328 5.257e-09 3.357e-07
16 DOUBLE STRANDED DNA BINDING 32 764 1.883e-08 1.093e-06
17 MACROMOLECULAR COMPLEX BINDING 46 1399 2.286e-08 1.249e-06
18 PHOSPHATIDYLINOSITOL KINASE ACTIVITY 9 51 2.658e-08 1.372e-06
19 SEQUENCE SPECIFIC DNA BINDING 38 1037 2.845e-08 1.391e-06
20 PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 14 178 1.654e-07 7.681e-06
21 TRANSCRIPTION FACTOR BINDING 24 524 2.543e-07 1.125e-05
22 CORE PROMOTER BINDING 12 152 1.228e-06 5.185e-05
23 PHOSPHATASE ACTIVITY 16 275 1.306e-06 5.276e-05
24 PHOSPHATIDYLINOSITOL PHOSPHATE KINASE ACTIVITY 5 16 1.764e-06 6.829e-05
25 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 12 168 3.514e-06 0.0001306
26 PROTEIN COMPLEX BINDING 31 935 4.833e-06 0.0001727
27 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 16 315 7.471e-06 0.0002571
28 CORE PROMOTER SEQUENCE SPECIFIC DNA BINDING 9 101 1.007e-05 0.0003341
29 ACTIVATING TRANSCRIPTION FACTOR BINDING 7 57 1.207e-05 0.0003866
30 PHOSPHORIC ESTER HYDROLASE ACTIVITY 17 368 1.344e-05 0.0004027
31 LIGASE ACTIVITY 18 406 1.305e-05 0.0004027
32 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 13 226 1.471e-05 0.0004269
33 PROTEIN DOMAIN SPECIFIC BINDING 23 624 1.691e-05 0.0004762
34 RECEPTOR BINDING 40 1476 2.428e-05 0.0006634
35 RNA POLYMERASE II REPRESSING TRANSCRIPTION FACTOR BINDING 5 27 2.884e-05 0.0007654
36 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC BINDING 8 90 3.206e-05 0.0008049
37 PROTEIN TYROSINE SERINE THREONINE PHOSPHATASE ACTIVITY 6 45 3.19e-05 0.0008049
38 PROTEIN PHOSPHATASE BINDING 9 120 4.026e-05 0.0009842
39 ATPASE ACTIVITY COUPLED TO MOVEMENT OF SUBSTANCES 9 121 4.298e-05 0.001024
40 SMAD BINDING 7 72 5.649e-05 0.001312
41 TRANSCRIPTION COACTIVATOR ACTIVITY 14 296 6.052e-05 0.001371
42 INSULIN RECEPTOR BINDING 5 32 6.803e-05 0.001505
43 PHOSPHATASE BINDING 10 162 7.977e-05 0.001723
44 MAGNESIUM ION BINDING 11 199 9.565e-05 0.001953
45 MOLECULAR FUNCTION REGULATOR 36 1353 9.373e-05 0.001953
46 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 8 105 9.672e-05 0.001953
47 RNA POLYMERASE II ACTIVATING TRANSCRIPTION FACTOR BINDING 5 36 0.0001218 0.002399
48 REPRESSING TRANSCRIPTION FACTOR BINDING 6 57 0.0001239 0.002399
49 ACID THIOL LIGASE ACTIVITY 4 20 0.0001385 0.002626
50 PROTEIN TYROSINE KINASE ACTIVITY 10 176 0.0001583 0.002941
51 PROTEIN SERINE THREONINE PHOSPHATASE ACTIVITY 6 64 0.0002365 0.004307
52 ADENYLYLTRANSFERASE ACTIVITY 4 24 0.000291 0.005013
53 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 13 303 0.0002877 0.005013
54 UBIQUITIN LIKE PROTEIN LIGASE BINDING 12 264 0.0002914 0.005013
55 CHROMATIN BINDING 16 435 0.0003393 0.005731
56 ANION TRANSMEMBRANE TRANSPORTING ATPASE ACTIVITY 3 11 0.0003827 0.006349
57 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 19 588 0.0004886 0.007964
58 HISTONE ACETYLTRANSFERASE BINDING 4 28 0.0005371 0.008603
59 HISTONE DEACETYLASE BINDING 7 105 0.0005961 0.009386
60 RECEPTOR SIGNALING PROTEIN ACTIVITY 9 172 0.0006116 0.00947
NumGOOverlapSizeP ValueAdj. P Value
1 TRANSFERASE COMPLEX TRANSFERRING PHOSPHORUS CONTAINING GROUPS 16 237 1.786e-07 0.0001043
2 MEMBRANE MICRODOMAIN 16 288 2.384e-06 0.000464
3 MEMBRANE REGION 36 1134 2.111e-06 0.000464
4 LAMELLIPODIUM 12 172 4.484e-06 0.0005829
5 CELL CELL JUNCTION 18 383 5.905e-06 0.0005829
6 PHOSPHATIDYLINOSITOL 3 KINASE COMPLEX 5 20 5.988e-06 0.0005829
7 PLASMA MEMBRANE REGION 30 929 1.157e-05 0.0009652
8 CATALYTIC COMPLEX 32 1038 1.475e-05 0.001077
9 PLASMA MEMBRANE RAFT 8 86 2.3e-05 0.001492
10 PROTEIN KINASE COMPLEX 8 90 3.206e-05 0.001872
11 TRANSFERASE COMPLEX 24 703 3.806e-05 0.002021
12 CELL JUNCTION 33 1151 4.576e-05 0.002063
13 EXTRINSIC COMPONENT OF MEMBRANE 13 252 4.592e-05 0.002063
14 CELL LEADING EDGE 15 350 0.0001007 0.004201
15 CILIARY BASAL BODY 7 81 0.0001202 0.004678

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 FoxO_signaling_pathway_hsa04068 18 132 2.637e-13 1.371e-11
2 PI3K_Akt_signaling_pathway_hsa04151 25 352 1.875e-11 4.875e-10
3 AMPK_signaling_pathway_hsa04152 13 121 1.134e-08 1.966e-07
4 MAPK_signaling_pathway_hsa04010 18 295 1.388e-07 1.805e-06
5 ErbB_signaling_pathway_hsa04012 10 85 2.422e-07 2.519e-06
6 Cellular_senescence_hsa04218 13 160 3.159e-07 2.738e-06
7 ABC_transporters_hsa02010 7 45 2.382e-06 1.769e-05
8 Autophagy_animal_hsa04140 10 128 1.05e-05 6.826e-05
9 Ras_signaling_pathway_hsa04014 13 232 1.941e-05 0.0001023
10 Focal_adhesion_hsa04510 12 199 1.967e-05 0.0001023
11 Phospholipase_D_signaling_pathway_hsa04072 10 146 3.305e-05 0.0001562
12 Hippo_signaling_pathway_hsa04390 10 154 5.209e-05 0.0002257
13 Adherens_junction_hsa04520 7 72 5.649e-05 0.000226
14 cGMP_PKG_signaling_pathway_hsa04022 10 163 8.398e-05 0.0003119
15 Regulation_of_actin_cytoskeleton_hsa04810 11 208 0.0001415 0.0004904
16 HIF_1_signaling_pathway_hsa04066 7 100 0.0004441 0.001443
17 TNF_signaling_pathway_hsa04668 7 108 0.0007055 0.002158
18 mTOR_signaling_pathway_hsa04150 8 151 0.001125 0.003251
19 Sphingolipid_signaling_pathway_hsa04071 7 118 0.001189 0.003254
20 VEGF_signaling_pathway_hsa04370 5 59 0.001253 0.003259
21 Tight_junction_hsa04530 8 170 0.00238 0.005893
22 Apelin_signaling_pathway_hsa04371 7 137 0.002789 0.006568
23 Apoptosis_hsa04210 7 138 0.002905 0.006568
24 Jak_STAT_signaling_pathway_hsa04630 7 162 0.006945 0.01378
25 Hippo_signaling_pathway_multiple_species_hsa04392 3 29 0.007071 0.01378
26 Gap_junction_hsa04540 5 88 0.00713 0.01378
27 Cell_cycle_hsa04110 6 124 0.007156 0.01378
28 Rap1_signaling_pathway_hsa04015 8 206 0.007516 0.01396
29 Phosphatidylinositol_signaling_system_hsa04070 5 99 0.01154 0.0207
30 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 6 139 0.01217 0.02109
31 Calcium_signaling_pathway_hsa04020 7 182 0.01268 0.02128
32 p53_signaling_pathway_hsa04115 4 68 0.01397 0.02271
33 Wnt_signaling_pathway_hsa04310 6 146 0.0152 0.02395
34 Oocyte_meiosis_hsa04114 5 124 0.02771 0.04238
35 NF_kappa_B_signaling_pathway_hsa04064 4 95 0.04121 0.06123
36 Necroptosis_hsa04217 5 164 0.07457 0.1077
37 TGF_beta_signaling_pathway_hsa04350 3 84 0.1075 0.1511
38 Endocytosis_hsa04144 6 244 0.1182 0.1617
39 Hedgehog_signaling_pathway_hsa04340 2 47 0.1348 0.1797
40 Mitophagy_animal_hsa04137 2 65 0.2225 0.2892
41 cAMP_signaling_pathway_hsa04024 4 198 0.2857 0.3624
42 Phagosome_hsa04145 3 152 0.3438 0.4256
43 Cytokine_cytokine_receptor_interaction_hsa04060 4 270 0.5048 0.5706

Quest ID: a0d9bf44e9591811cd765bc599f94e4a