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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-484 ABCA4 -0.69 0 0.93 0 MirTarget -0.41 0 NA
2 hsa-miR-107 ABCC3 -0.18 0.01038 2.55 0 miRanda; miRNATAP -0.83 0 NA
3 hsa-miR-107 ABCC5 -0.18 0.01038 -0.18 0.03187 miRanda -0.14 0.00522 NA
4 hsa-miR-326 ABCC6P1 -1 0 2.57 0 miRanda -0.16 0.0077 NA
5 hsa-miR-421 ABCC6P1 -0.4 0.00042 2.57 0 miRanda -0.36 3.0E-5 NA
6 hsa-miR-346 ABCC9 0.06 0.73455 -0.84 0 miRanda -0.15 0.00011 NA
7 hsa-miR-421 ABCD2 -0.4 0.00042 -0.98 1.0E-5 miRanda -0.2 0.01229 NA
8 hsa-miR-484 ABHD12 -0.69 0 -0.01 0.83468 miRNAWalker2 validate -0.16 0 NA
9 hsa-miR-484 ABHD2 -0.69 0 -0.33 0.00046 miRNAWalker2 validate -0.16 4.0E-5 NA
10 hsa-miR-421 ABHD3 -0.4 0.00042 0.36 0.00014 miRanda -0.13 0.0002 NA
11 hsa-miR-375 ABHD6 2.28 0 -0.33 3.0E-5 miRanda -0.1 0 NA
12 hsa-miR-107 ABR -0.18 0.01038 1.52 0 miRanda -0.34 0 NA
13 hsa-miR-107 ACAP3 -0.18 0.01038 0.41 0 miRNATAP -0.11 0.00858 NA
14 hsa-miR-421 ACOT9 -0.4 0.00042 0.39 0 miRNAWalker2 validate; miRanda -0.12 0 NA
15 hsa-miR-429 ACSL6 -0.07 0.78851 -2.13 0 miRNATAP -0.16 3.0E-5 NA
16 hsa-miR-592 ACSL6 0.07 0.70172 -2.13 0 PITA -0.18 0.00132 NA
17 hsa-miR-1270 ACTBL2 -1.08 0 3.87 0 MirTarget; miRNATAP -0.27 0.00511 NA
18 hsa-miR-577 ACTBL2 -1.63 0 3.87 0 mirMAP -0.73 0 NA
19 hsa-miR-107 ACTG1 -0.18 0.01038 0.35 0 miRanda; miRNATAP -0.12 9.0E-5 NA
20 hsa-miR-421 ACTN1 -0.4 0.00042 1.02 0 miRanda -0.24 0 NA
21 hsa-miR-107 ACVR1 -0.18 0.01038 0.68 0 miRanda -0.22 4.0E-5 NA
22 hsa-miR-484 ADAM10 -0.69 0 -0.39 0.00177 miRNAWalker2 validate -0.16 0.00158 NA
23 hsa-miR-3170 ADAM12 0.26 0.06427 1.77 0 mirMAP -0.2 0.01266 NA
24 hsa-miR-346 ADAM12 0.06 0.73455 1.77 0 PITA; miRanda -0.25 0.0002 NA
25 hsa-miR-421 ADAM12 -0.4 0.00042 1.77 0 mirMAP; miRNATAP -0.57 0 NA
26 hsa-miR-935 ADAM12 0.31 0.06191 1.77 0 miRNATAP -0.25 0.00033 NA
27 hsa-miR-107 ADAM15 -0.18 0.01038 0.82 0 miRanda -0.17 0.0001 NA
28 hsa-miR-421 ADAM19 -0.4 0.00042 -0.28 0.11381 mirMAP -0.24 0.00023 NA
29 hsa-miR-375 ADAM22 2.28 0 -2.81 0 miRanda -0.44 0 NA
30 hsa-miR-346 ADAM28 0.06 0.73455 0.01 0.95681 miRanda -0.25 0 NA
31 hsa-miR-326 ADAMTS10 -1 0 0.87 0 mirMAP -0.12 0.00014 NA
32 hsa-miR-326 ADAMTS13 -1 0 -0.52 0 mirMAP -0.12 0 NA
33 hsa-miR-107 ADAMTS14 -0.18 0.01038 3.41 0 miRanda -1.46 0 NA
34 hsa-miR-940 ADAMTS14 -0.57 0.00022 3.41 0 mirMAP -0.73 0 NA
35 hsa-miR-1976 ADAMTS15 -0.57 0 -0.54 0.00965 mirMAP -0.2 0.04203 NA
36 hsa-miR-484 ADAMTS15 -0.69 0 -0.54 0.00965 mirMAP -0.47 0 NA
37 hsa-miR-346 ADAMTS16 0.06 0.73455 -0.4 0.10351 miRanda -0.17 0.00494 NA
38 hsa-miR-577 ADAMTS17 -1.63 0 0.64 0 mirMAP -0.17 0 NA
39 hsa-miR-326 ADAMTS18 -1 0 2.15 0 miRanda -0.17 0.01252 NA
40 hsa-miR-421 ADAMTS18 -0.4 0.00042 2.15 0 miRanda; miRNATAP -0.22 0.0224 NA
41 hsa-miR-577 ADAMTS18 -1.63 0 2.15 0 PITA -0.28 0 NA
42 hsa-miR-375 ADAMTS3 2.28 0 -0.99 0 miRanda -0.23 0 NA
43 hsa-miR-107 ADAMTS6 -0.18 0.01038 0.39 0.01384 miRanda -0.2 0.03503 NA
44 hsa-miR-346 ADAMTS6 0.06 0.73455 0.39 0.01384 MirTarget; PITA; miRanda -0.14 0.00064 NA
45 hsa-miR-577 ADAMTS6 -1.63 0 0.39 0.01384 PITA; mirMAP; miRNATAP -0.15 0 NA
46 hsa-miR-107 ADAMTSL1 -0.18 0.01038 -0.23 0.20826 miRanda -0.38 0.00048 NA
47 hsa-miR-346 ADAMTSL1 0.06 0.73455 -0.23 0.20826 miRanda; miRNATAP -0.14 0.00167 NA
48 hsa-miR-421 ADAMTSL1 -0.4 0.00042 -0.23 0.20826 miRanda -0.22 0.00119 NA
49 hsa-miR-107 ADAP2 -0.18 0.01038 0.95 0 miRanda -0.2 0.00199 NA
50 hsa-miR-107 ADAR -0.18 0.01038 0.17 0.00125 miRanda -0.13 5.0E-5 NA
51 hsa-miR-484 ADAR -0.69 0 0.17 0.00125 miRNAWalker2 validate -0.17 0 NA
52 hsa-miR-107 ADARB1 -0.18 0.01038 0.52 0 miRanda -0.1 0.03551 NA
53 hsa-miR-1976 ADARB1 -0.57 0 0.52 0 MirTarget; mirMAP -0.25 0 NA
54 hsa-miR-375 ADAT2 2.28 0 -0.57 0 miRNATAP -0.1 0 NA
55 hsa-miR-484 ADCK2 -0.69 0 0.06 0.20356 miRNAWalker2 validate -0.1 0 NA
56 hsa-miR-592 ADCY1 0.07 0.70172 -0.58 0.00043 mirMAP -0.1 0.00755 NA
57 hsa-miR-107 ADCYAP1 -0.18 0.01038 -0.38 0.19309 MirTarget; PITA; miRanda; miRNATAP -0.35 0.04932 NA
58 hsa-miR-592 ADCYAP1R1 0.07 0.70172 -0.93 0.00282 mirMAP -0.14 0.04992 NA
59 hsa-miR-107 ADD2 -0.18 0.01038 -0.53 0.01427 miRNAWalker2 validate; miRNATAP -0.31 0.01557 NA
60 hsa-miR-346 ADD2 0.06 0.73455 -0.53 0.01427 miRanda -0.18 0.00076 NA
61 hsa-miR-375 ADIPOR2 2.28 0 -0.65 0 miRNAWalker2 validate; miRTarBase -0.13 0 NA
62 hsa-miR-107 ADK -0.18 0.01038 1.02 0 miRanda -0.1 0.03034 NA
63 hsa-miR-577 ADK -1.63 0 1.02 0 miRNATAP -0.12 0 NA
64 hsa-miR-1976 ADORA1 -0.57 0 2.48 0 mirMAP -0.62 0 NA
65 hsa-miR-421 ADORA3 -0.4 0.00042 1.02 0 miRanda -0.24 0.00015 NA
66 hsa-miR-326 ADRA2C -1 0 1.34 0 miRanda -0.13 0.01139 NA
67 hsa-miR-107 ADRB2 -0.18 0.01038 -0.77 0 miRanda -0.2 0.03212 NA
68 hsa-miR-107 AFF2 -0.18 0.01038 1.69 0 mirMAP; miRNATAP -0.7 0 NA
69 hsa-miR-421 AFF2 -0.4 0.00042 1.69 0 mirMAP -0.41 0 NA
70 hsa-miR-577 AFF2 -1.63 0 1.69 0 PITA; mirMAP -0.37 0 NA
71 hsa-miR-940 AFF2 -0.57 0.00022 1.69 0 miRNATAP -0.25 4.0E-5 NA
72 hsa-miR-940 AGRN -0.57 0.00022 1.11 0 MirTarget -0.17 0 NA
73 hsa-miR-421 AGT -0.4 0.00042 0.83 0.0001 miRanda -0.24 0.00223 NA
74 hsa-miR-326 AGTRAP -1 0 0.69 0 miRanda -0.13 0 NA
75 hsa-miR-107 AHNAK -0.18 0.01038 -0.27 0.01079 miRanda -0.2 0.00108 NA
76 hsa-miR-421 AHNAK -0.4 0.00042 -0.27 0.01079 miRNAWalker2 validate -0.13 0.00062 NA
77 hsa-miR-577 AHR -1.63 0 0.92 0 MirTarget; PITA; miRNATAP -0.24 0 NA
78 hsa-miR-107 AHSA2 -0.18 0.01038 0.04 0.73127 miRanda -0.17 0.02916 NA
79 hsa-miR-107 AIM1L -0.18 0.01038 2.36 0 miRanda -0.71 0 NA
80 hsa-miR-484 AKAP13 -0.69 0 0.11 0.18324 miRNAWalker2 validate -0.3 0 NA
81 hsa-miR-107 AKIRIN2 -0.18 0.01038 0.4 0 miRanda -0.13 7.0E-5 NA
82 hsa-miR-484 AKNA -0.69 0 0.4 0.00027 mirMAP -0.27 0 NA
83 hsa-miR-940 AKNA -0.57 0.00022 0.4 0.00027 miRNATAP -0.15 0 NA
84 hsa-miR-107 AKT3 -0.18 0.01038 -0.02 0.82269 PITA; miRanda -0.17 0.00039 NA
85 hsa-miR-421 AKT3 -0.4 0.00042 -0.02 0.82269 miRanda; mirMAP -0.11 0.00023 NA
86 hsa-miR-577 ALDH1A3 -1.63 0 2.52 0 PITA; miRNATAP -0.46 0 NA
87 hsa-miR-217 ALDH1L1 -0.33 0.18796 -1.34 0 miRanda -0.1 0.0342 NA
88 hsa-miR-346 ALDH1L2 0.06 0.73455 -1.01 0 MirTarget; miRanda -0.24 0 NA
89 hsa-miR-940 ALDH3B1 -0.57 0.00022 2.35 0 MirTarget -0.47 0 NA
90 hsa-miR-107 ALDH3B2 -0.18 0.01038 3.1 0 miRanda -0.87 0 NA
91 hsa-miR-326 ALOX12P2 -1 0 0.18 0.46479 miRanda -0.15 0.01217 NA
92 hsa-miR-421 ALPK2 -0.4 0.00042 -0.22 0.54142 miRanda -0.59 1.0E-5 NA
93 hsa-miR-326 ALS2CL -1 0 0.53 0 MirTarget; miRanda; mirMAP -0.15 0 NA
94 hsa-miR-940 ALS2CL -0.57 0.00022 0.53 0 MirTarget -0.13 0 NA
95 hsa-miR-326 AMIGO2 -1 0 2.15 0 miRanda -0.16 0.00114 NA
96 hsa-miR-484 AMMECR1 -0.69 0 0.27 0 miRNATAP -0.11 0 NA
97 hsa-miR-107 AMOT -0.18 0.01038 0.84 0 MirTarget; PITA; miRanda; miRNATAP -0.5 0 NA
98 hsa-miR-577 AMOT -1.63 0 0.84 0 mirMAP -0.27 0 NA
99 hsa-miR-484 AMOTL1 -0.69 0 -0.36 1.0E-5 miRNAWalker2 validate; MirTarget -0.11 0.00075 NA
100 hsa-miR-107 AMPH -0.18 0.01038 -0.69 0.00031 miRanda -0.26 0.02181 NA
101 hsa-miR-577 AMPH -1.63 0 -0.69 0.00031 mirMAP -0.13 0.00011 NA
102 hsa-miR-107 AMT -0.18 0.01038 -0.2 0.1701 miRanda -0.18 0.0364 NA
103 hsa-miR-484 ANAPC1 -0.69 0 -0.23 0.00491 miRNAWalker2 validate -0.18 0 NA
104 hsa-miR-421 ANG -0.4 0.00042 0.05 0.72687 miRanda -0.22 0 NA
105 hsa-miR-107 ANK1 -0.18 0.01038 -0.67 0.00014 PITA; miRanda; miRNATAP -0.4 0.00014 NA
106 hsa-miR-1976 ANKFY1 -0.57 0 0.51 0 miRNATAP -0.13 1.0E-5 NA
107 hsa-miR-484 ANKFY1 -0.69 0 0.51 0 mirMAP -0.31 0 NA
108 hsa-miR-940 ANKFY1 -0.57 0.00022 0.51 0 MirTarget -0.13 0 NA
109 hsa-miR-421 ANKH -0.4 0.00042 0.59 0 miRanda -0.23 0 NA
110 hsa-miR-577 ANKH -1.63 0 0.59 0 mirMAP -0.15 0 NA
111 hsa-miR-421 ANKRD10 -0.4 0.00042 0.15 0.02281 miRanda -0.13 0 NA
112 hsa-miR-421 ANKRD13B -0.4 0.00042 0.28 0.00672 miRanda -0.16 2.0E-5 NA
113 hsa-miR-107 ANKRD30B -0.18 0.01038 2.11 0 miRanda -0.91 0 NA
114 hsa-miR-107 ANKRD36 -0.18 0.01038 -0.15 0.13119 miRanda -0.12 0.04535 NA
115 hsa-miR-421 ANKRD36 -0.4 0.00042 -0.15 0.13119 miRanda -0.13 0.00021 NA
116 hsa-miR-107 ANKRD44 -0.18 0.01038 -0.68 0.00013 miRanda -0.26 0.01285 NA
117 hsa-miR-375 ANKRD46 2.28 0 -0.74 0 miRNAWalker2 validate -0.14 0 NA
118 hsa-miR-326 ANKS3 -1 0 -0.17 0.03751 miRNATAP -0.13 0 NA
119 hsa-miR-326 ANKS6 -1 0 0.59 0 MirTarget; miRNATAP -0.1 0 NA
120 hsa-miR-421 ANKS6 -0.4 0.00042 0.59 0 mirMAP -0.13 0 NA
121 hsa-miR-421 ANO6 -0.4 0.00042 0.66 0 miRanda -0.12 0.00412 NA
122 hsa-miR-577 ANO6 -1.63 0 0.66 0 MirTarget; mirMAP; miRNATAP -0.16 0 NA
123 hsa-miR-421 ANO7 -0.4 0.00042 0.91 0 miRanda -0.11 0.00215 NA
124 hsa-miR-107 ANXA1 -0.18 0.01038 1.54 0 miRanda -0.59 0 NA
125 hsa-miR-484 ANXA11 -0.69 0 0.34 0 miRNAWalker2 validate; mirMAP -0.14 0 NA
126 hsa-miR-107 ANXA4 -0.18 0.01038 0.11 0.07028 miRanda -0.1 0.00669 NA
127 hsa-miR-326 AP1M2 -1 0 0.6 0 miRNATAP -0.14 0 NA
128 hsa-miR-107 AP2A1 -0.18 0.01038 0.52 0 miRanda -0.17 0 NA
129 hsa-miR-484 AP2M1 -0.69 0 0.44 0 miRNAWalker2 validate -0.12 0 NA
130 hsa-miR-346 APOBEC2 0.06 0.73455 0.97 0 miRanda -0.1 0.03613 NA
131 hsa-miR-107 APOBEC3C -0.18 0.01038 0.02 0.83693 miRanda -0.3 0 NA
132 hsa-miR-107 APOBEC3D -0.18 0.01038 -0.4 0.00993 miRanda -0.52 0 NA
133 hsa-miR-484 APOOL -0.69 0 -0.56 0.00037 MirTarget -0.26 9.0E-5 NA
134 hsa-miR-375 AQP4 2.28 0 -2.17 0 miRanda -0.19 0 NA
135 hsa-miR-592 AQP4 0.07 0.70172 -2.17 0 mirMAP -0.2 0.0045 NA
136 hsa-miR-484 ARAP1 -0.69 0 0.62 0 miRNAWalker2 validate -0.3 0 NA
137 hsa-miR-107 AREG -0.18 0.01038 1.21 9.0E-5 miRanda -0.49 0.00903 NA
138 hsa-miR-107 ARF6 -0.18 0.01038 0.28 0 MirTarget; miRanda -0.13 0.00032 NA
139 hsa-miR-484 ARFGEF2 -0.69 0 -0.09 0.30981 miRNAWalker2 validate -0.25 0 NA
140 hsa-miR-2110 ARGLU1 -0.1 0.48444 -0.17 0.08004 MirTarget -0.11 8.0E-5 NA
141 hsa-miR-107 ARHGAP1 -0.18 0.01038 0.44 0 miRanda -0.21 0 NA
142 hsa-miR-107 ARHGAP18 -0.18 0.01038 0.72 0 miRanda -0.14 0.01364 NA
143 hsa-miR-107 ARHGAP19 -0.18 0.01038 0.99 0 MirTarget; miRanda; mirMAP -0.2 0.02303 NA
144 hsa-miR-421 ARHGAP19 -0.4 0.00042 0.99 0 MirTarget; miRanda -0.17 0.00096 NA
145 hsa-miR-484 ARHGAP19 -0.69 0 0.99 0 mirMAP -0.53 0 NA
146 hsa-miR-577 ARHGAP19 -1.63 0 0.99 0 mirMAP -0.25 0 NA
147 hsa-miR-940 ARHGAP19 -0.57 0.00022 0.99 0 mirMAP -0.25 0 NA
148 hsa-miR-346 ARHGAP25 0.06 0.73455 -0.16 0.23046 miRanda -0.14 3.0E-5 NA
149 hsa-miR-484 ARHGAP32 -0.69 0 -0.09 0.30353 MirTarget; mirMAP -0.17 0 NA
150 hsa-miR-2110 ARHGAP33 -0.1 0.48444 -0.49 0.00011 MirTarget -0.13 0.00034 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 BIOLOGICAL ADHESION 258 1032 3.94e-37 1.833e-33
2 IMMUNE SYSTEM PROCESS 398 1984 1.345e-33 3.129e-30
3 POSITIVE REGULATION OF RESPONSE TO STIMULUS 377 1929 2.66e-29 4.126e-26
4 LOCOMOTION 251 1114 1.763e-28 2.051e-25
5 REGULATION OF CELLULAR COMPONENT MOVEMENT 189 771 4.392e-26 4.087e-23
6 POSITIVE REGULATION OF CELL COMMUNICATION 305 1532 7.223e-25 5.601e-22
7 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 264 1275 4.723e-24 3.139e-21
8 REGULATION OF CELL DIFFERENTIATION 296 1492 7.166e-24 4.168e-21
9 CELL MOTILITY 194 835 9.82e-24 4.569e-21
10 LOCALIZATION OF CELL 194 835 9.82e-24 4.569e-21
11 REGULATION OF CELL PROLIFERATION 295 1496 2.321e-23 9.82e-21
12 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 320 1672 3.926e-23 1.522e-20
13 REGULATION OF IMMUNE SYSTEM PROCESS 280 1403 5.729e-23 2.051e-20
14 REGULATION OF CELL ADHESION 157 629 1.226e-22 4.075e-20
15 IMMUNE RESPONSE 232 1100 3.063e-22 9.503e-20
16 POSITIVE REGULATION OF MOLECULAR FUNCTION 333 1791 6.458e-22 1.768e-19
17 REGULATION OF CELLULAR LOCALIZATION 258 1277 6.228e-22 1.768e-19
18 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 275 1395 9.559e-22 2.471e-19
19 CELL ACTIVATION 144 568 1.604e-21 3.929e-19
20 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 217 1021 2.951e-21 6.864e-19
21 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 310 1656 7.65e-21 1.695e-18
22 POSITIVE REGULATION OF CATALYTIC ACTIVITY 290 1518 8.152e-21 1.724e-18
23 CELL CELL ADHESION 149 608 1.03e-20 2.084e-18
24 INTRACELLULAR SIGNAL TRANSDUCTION 297 1572 1.424e-20 2.76e-18
25 REGULATION OF TRANSPORT 330 1804 1.54e-20 2.866e-18
26 SINGLE ORGANISM CELL ADHESION 121 459 1.011e-19 1.81e-17
27 TISSUE DEVELOPMENT 286 1518 1.247e-19 2.149e-17
28 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 188 867 1.769e-19 2.939e-17
29 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 230 1142 2.083e-19 3.342e-17
30 EXTRACELLULAR STRUCTURE ORGANIZATION 91 304 5.579e-19 8.653e-17
31 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 187 876 1.286e-18 1.93e-16
32 POSITIVE REGULATION OF CELL PROLIFERATION 176 814 3.735e-18 5.43e-16
33 NEUROGENESIS 264 1402 4.224e-18 5.956e-16
34 REGULATION OF CELL ACTIVATION 120 484 2.615e-17 3.579e-15
35 CARDIOVASCULAR SYSTEM DEVELOPMENT 169 788 4.122e-17 5.327e-15
36 CIRCULATORY SYSTEM DEVELOPMENT 169 788 4.122e-17 5.327e-15
37 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 254 1360 5.715e-17 7.187e-15
38 RESPONSE TO EXTERNAL STIMULUS 318 1821 1.015e-16 1.243e-14
39 ORGAN MORPHOGENESIS 176 841 1.106e-16 1.319e-14
40 LEUKOCYTE ACTIVATION 106 414 1.828e-16 2.126e-14
41 NEGATIVE REGULATION OF CELL COMMUNICATION 226 1192 6.561e-16 7.446e-14
42 TAXIS 113 464 9.009e-16 9.98e-14
43 REGULATION OF CELL DEVELOPMENT 172 836 1.347e-15 1.458e-13
44 LEUKOCYTE MIGRATION 76 259 1.506e-15 1.593e-13
45 POSITIVE REGULATION OF CELL DIFFERENTIATION 169 823 2.913e-15 3.012e-13
46 VASCULATURE DEVELOPMENT 112 469 5.257e-15 5.317e-13
47 LYMPHOCYTE ACTIVATION 90 342 6.088e-15 6.027e-13
48 REGULATION OF PROTEIN LOCALIZATION 187 950 6.758e-15 6.551e-13
49 POSITIVE REGULATION OF HYDROLASE ACTIVITY 180 905 8.228e-15 7.814e-13
50 REGULATION OF PHOSPHORUS METABOLIC PROCESS 282 1618 9.637e-15 8.968e-13
51 POSITIVE REGULATION OF LOCOMOTION 103 420 1.065e-14 9.713e-13
52 REGULATION OF KINASE ACTIVITY 160 776 1.155e-14 1.033e-12
53 RESPONSE TO OXYGEN CONTAINING COMPOUND 248 1381 1.621e-14 1.407e-12
54 RESPONSE TO CYTOKINE 150 714 1.633e-14 1.407e-12
55 CELL DEVELOPMENT 254 1426 1.976e-14 1.672e-12
56 REGULATION OF PROTEIN MODIFICATION PROCESS 293 1710 2.465e-14 2.048e-12
57 REGULATION OF IMMUNE RESPONSE 171 858 3.347e-14 2.732e-12
58 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 181 926 3.732e-14 2.994e-12
59 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 311 1848 3.845e-14 3.032e-12
60 POSITIVE REGULATION OF CELL ADHESION 94 376 4.565e-14 3.54e-12
61 REGULATION OF HYDROLASE ACTIVITY 238 1327 6.775e-14 5.168e-12
62 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 196 1036 8.268e-14 6.107e-12
63 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 196 1036 8.268e-14 6.107e-12
64 POSITIVE REGULATION OF KINASE ACTIVITY 111 482 9.577e-14 6.963e-12
65 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 188 983 9.793e-14 7.01e-12
66 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 153 750 1.135e-13 8.002e-12
67 BLOOD VESSEL MORPHOGENESIS 91 364 1.163e-13 8.08e-12
68 REGULATION OF SECRETION 145 699 1.31e-13 8.967e-12
69 REGULATION OF CELL PROJECTION ORGANIZATION 122 558 2.833e-13 1.91e-11
70 RESPONSE TO LIPID 172 888 3.834e-13 2.548e-11
71 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 114 513 5.622e-13 3.684e-11
72 REGULATION OF GTPASE ACTIVITY 139 673 6.049e-13 3.909e-11
73 TISSUE MORPHOGENESIS 117 533 6.641e-13 4.233e-11
74 REGULATION OF CELL MORPHOGENESIS 120 552 6.742e-13 4.239e-11
75 LEUKOCYTE CELL CELL ADHESION 70 255 7.158e-13 4.441e-11
76 POSITIVE REGULATION OF TRANSPORT 178 936 7.822e-13 4.789e-11
77 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 209 1152 8.575e-13 5.182e-11
78 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 299 1805 9.529e-13 5.658e-11
79 DEFENSE RESPONSE 220 1231 9.607e-13 5.658e-11
80 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 157 801 1.622e-12 9.432e-11
81 EPITHELIUM DEVELOPMENT 178 945 1.852e-12 1.064e-10
82 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 205 1135 2.235e-12 1.268e-10
83 REGULATION OF CYTOKINE PRODUCTION 120 563 2.746e-12 1.513e-10
84 RESPONSE TO WOUNDING 120 563 2.746e-12 1.513e-10
85 REGULATION OF HOMOTYPIC CELL CELL ADHESION 78 307 2.764e-12 1.513e-10
86 REGULATION OF CELL CELL ADHESION 90 380 4.197e-12 2.271e-10
87 REGULATION OF NEURON DIFFERENTIATION 118 554 4.397e-12 2.352e-10
88 CELL PROLIFERATION 136 672 5.081e-12 2.687e-10
89 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 253 1492 5.865e-12 3.066e-10
90 TUBE DEVELOPMENT 117 552 7.585e-12 3.922e-10
91 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 138 689 7.722e-12 3.949e-10
92 REGULATION OF MAP KINASE ACTIVITY 79 319 8.121e-12 4.107e-10
93 CELLULAR RESPONSE TO CYTOKINE STIMULUS 125 606 1.006e-11 5.031e-10
94 REGULATION OF TRANSFERASE ACTIVITY 175 946 1.379e-11 6.827e-10
95 POSITIVE REGULATION OF MAPK CASCADE 103 470 1.803e-11 8.74e-10
96 WOUND HEALING 103 470 1.803e-11 8.74e-10
97 REGULATION OF CELL DEATH 248 1472 1.929e-11 9.252e-10
98 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 176 957 1.984e-11 9.418e-10
99 REGULATION OF RESPONSE TO STRESS 247 1468 2.442e-11 1.148e-09
100 REGULATION OF MAPK CASCADE 132 660 2.481e-11 1.154e-09
101 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 182 1004 3.091e-11 1.424e-09
102 POSITIVE REGULATION OF CELL ACTIVATION 76 311 4.019e-11 1.816e-09
103 POSITIVE REGULATION OF CELL DEATH 123 605 3.999e-11 1.816e-09
104 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 102 470 4.114e-11 1.841e-09
105 ADAPTIVE IMMUNE RESPONSE 72 288 4.268e-11 1.891e-09
106 INFLAMMATORY RESPONSE 99 454 6.006e-11 2.636e-09
107 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 124 616 6.541e-11 2.844e-09
108 NEURON DIFFERENTIATION 162 874 7.08e-11 3.05e-09
109 MORPHOGENESIS OF AN EPITHELIUM 90 400 7.994e-11 3.413e-09
110 NEGATIVE REGULATION OF TRANSPORT 99 458 1.009e-10 4.269e-09
111 REGULATION OF NEURON PROJECTION DEVELOPMENT 91 408 1.027e-10 4.305e-09
112 IMMUNE SYSTEM DEVELOPMENT 118 582 1.202e-10 4.992e-09
113 CELL CHEMOTAXIS 48 162 1.675e-10 6.896e-09
114 REGULATION OF ION TRANSPORT 119 592 1.754e-10 7.159e-09
115 REGULATION OF GROWTH 125 633 1.996e-10 8.007e-09
116 DEVELOPMENTAL GROWTH 78 333 1.984e-10 8.007e-09
117 POSITIVE REGULATION OF CYTOKINE PRODUCTION 84 370 2.131e-10 8.476e-09
118 REGULATION OF ANATOMICAL STRUCTURE SIZE 100 472 2.639e-10 1.032e-08
119 NEGATIVE REGULATION OF CELL DIFFERENTIATION 121 609 2.634e-10 1.032e-08
120 REGULATION OF CHEMOTAXIS 51 180 2.701e-10 1.047e-08
121 REGULATION OF SYSTEM PROCESS 105 507 3.694e-10 1.421e-08
122 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 283 1784 5.29e-10 2.018e-08
123 REGULATION OF CELL SUBSTRATE ADHESION 49 173 6.091e-10 2.304e-08
124 REGULATION OF LEUKOCYTE PROLIFERATION 55 206 6.306e-10 2.366e-08
125 CELL CELL SIGNALING 143 767 6.433e-10 2.395e-08
126 TUBE MORPHOGENESIS 75 323 6.734e-10 2.487e-08
127 REGULATION OF CELLULAR PROTEIN LOCALIZATION 111 552 7.104e-10 2.603e-08
128 EMBRYO DEVELOPMENT 161 894 7.463e-10 2.713e-08
129 POSITIVE REGULATION OF GENE EXPRESSION 275 1733 9.336e-10 3.368e-08
130 MUSCLE STRUCTURE DEVELOPMENT 92 432 1.04e-09 3.723e-08
131 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 70 296 1.082e-09 3.815e-08
132 POSITIVE REGULATION OF CELL CELL ADHESION 61 243 1.082e-09 3.815e-08
133 NEGATIVE REGULATION OF CELL PROLIFERATION 124 643 1.103e-09 3.86e-08
134 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 102 498 1.245e-09 4.323e-08
135 RESPONSE TO ENDOGENOUS STIMULUS 236 1450 1.725e-09 5.903e-08
136 ANGIOGENESIS 69 293 1.717e-09 5.903e-08
137 REGULATION OF OSSIFICATION 49 178 1.758e-09 5.969e-08
138 INTEGRIN MEDIATED SIGNALING PATHWAY 30 82 1.843e-09 6.17e-08
139 REGULATION OF ORGANELLE ORGANIZATION 199 1178 1.83e-09 6.17e-08
140 REGULATION OF ACTIN FILAMENT BASED PROCESS 72 312 1.957e-09 6.505e-08
141 POSITIVE REGULATION OF MAP KINASE ACTIVITY 54 207 2.228e-09 7.354e-08
142 REGULATION OF RESPONSE TO WOUNDING 88 413 2.333e-09 7.596e-08
143 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 68 289 2.334e-09 7.596e-08
144 GLAND MORPHOGENESIS 33 97 2.518e-09 8.135e-08
145 NEURON PROJECTION MORPHOGENESIS 86 402 2.895e-09 9.291e-08
146 REGULATION OF LEUKOCYTE MIGRATION 43 149 3.602e-09 1.148e-07
147 REGULATION OF VASCULATURE DEVELOPMENT 58 233 3.866e-09 1.224e-07
148 REGULATION OF CELLULAR COMPONENT BIOGENESIS 140 767 4.113e-09 1.293e-07
149 EMBRYONIC ORGAN DEVELOPMENT 86 406 4.76e-09 1.486e-07
150 REGULATION OF MEMBRANE POTENTIAL 76 343 4.823e-09 1.496e-07
151 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 75 337 4.967e-09 1.53e-07
152 REGULATION OF MUSCLE SYSTEM PROCESS 51 195 5.612e-09 1.718e-07
153 REGULATION OF PROTEIN SECRETION 83 389 6.199e-09 1.877e-07
154 POSITIVE REGULATION OF SECRETION 80 370 6.213e-09 1.877e-07
155 CELLULAR COMPONENT MORPHOGENESIS 158 900 6.82e-09 2.047e-07
156 SKELETAL SYSTEM DEVELOPMENT 93 455 7.447e-09 2.221e-07
157 LEUKOCYTE DIFFERENTIATION 67 292 9.016e-09 2.672e-07
158 POSITIVE REGULATION OF IMMUNE RESPONSE 109 563 9.108e-09 2.682e-07
159 UROGENITAL SYSTEM DEVELOPMENT 68 299 1.025e-08 2.999e-07
160 MUSCLE TISSUE DEVELOPMENT 64 275 1.079e-08 3.118e-07
161 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 79 368 1.079e-08 3.118e-07
162 NEGATIVE REGULATION OF LOCOMOTION 62 263 1.086e-08 3.12e-07
163 EMBRYONIC MORPHOGENESIS 105 539 1.218e-08 3.477e-07
164 REGULATION OF METAL ION TRANSPORT 72 325 1.226e-08 3.48e-07
165 SECRETION BY CELL 97 486 1.255e-08 3.519e-07
166 IMMUNE EFFECTOR PROCESS 97 486 1.255e-08 3.519e-07
167 PROTEIN PHOSPHORYLATION 163 944 1.28e-08 3.568e-07
168 RESPONSE TO ABIOTIC STIMULUS 174 1024 1.332e-08 3.69e-07
169 SECRETION 112 588 1.447e-08 3.984e-07
170 RESPONSE TO ORGANIC CYCLIC COMPOUND 159 917 1.458e-08 3.991e-07
171 GROWTH 85 410 1.666e-08 4.533e-07
172 REGULATION OF EPITHELIAL CELL PROLIFERATION 65 285 1.917e-08 5.185e-07
173 PROTEIN LOCALIZATION 277 1805 2.242e-08 6.03e-07
174 CYTOKINE MEDIATED SIGNALING PATHWAY 91 452 2.302e-08 6.121e-07
175 POSITIVE REGULATION OF LEUKOCYTE PROLIFERATION 39 136 2.295e-08 6.121e-07
176 HEART DEVELOPMENT 93 466 2.514e-08 6.646e-07
177 REGULATION OF CELLULAR COMPONENT SIZE 73 337 2.617e-08 6.88e-07
178 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 125 684 2.647e-08 6.918e-07
179 CELL SUBSTRATE ADHESION 44 164 2.702e-08 7.024e-07
180 RESPONSE TO VIRUS 58 247 3.711e-08 9.594e-07
181 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 70 321 3.804e-08 9.779e-07
182 REGULATION OF DEFENSE RESPONSE 135 759 3.991e-08 1.02e-06
183 MULTI MULTICELLULAR ORGANISM PROCESS 52 213 4.839e-08 1.23e-06
184 REGULATION OF HORMONE SECRETION 60 262 5.7e-08 1.441e-06
185 POSITIVE REGULATION OF LEUKOCYTE MIGRATION 33 109 6.509e-08 1.637e-06
186 POSITIVE REGULATION OF CHEMOTAXIS 35 120 7.449e-08 1.863e-06
187 ACTIN FILAMENT BASED PROCESS 89 450 7.699e-08 1.916e-06
188 REGULATION OF DEVELOPMENTAL GROWTH 64 289 7.918e-08 1.96e-06
189 PHOSPHORYLATION 198 1228 8.098e-08 1.994e-06
190 REGULATION OF INTRACELLULAR TRANSPORT 114 621 8.533e-08 2.09e-06
191 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 111 602 9.982e-08 2.432e-06
192 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 98 514 1.102e-07 2.671e-06
193 RESPONSE TO ALCOHOL 75 362 1.177e-07 2.838e-06
194 RESPONSE TO OXYGEN LEVELS 67 311 1.202e-07 2.884e-06
195 REPRODUCTIVE SYSTEM DEVELOPMENT 82 408 1.22e-07 2.912e-06
196 NEGATIVE REGULATION OF MOLECULAR FUNCTION 177 1079 1.263e-07 2.998e-06
197 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 61 274 1.299e-07 3.068e-06
198 BEHAVIOR 98 516 1.336e-07 3.139e-06
199 MORPHOGENESIS OF A BRANCHING STRUCTURE 43 167 1.388e-07 3.246e-06
200 REGULATION OF PEPTIDE TRANSPORT 58 256 1.395e-07 3.247e-06
201 ALPHA BETA T CELL ACTIVATION 21 54 1.456e-07 3.365e-06
202 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 50 208 1.461e-07 3.365e-06
203 SYNAPSE ORGANIZATION 39 145 1.52e-07 3.473e-06
204 RESPONSE TO STEROID HORMONE 95 497 1.523e-07 3.473e-06
205 REGULATION OF INFLAMMATORY RESPONSE 64 294 1.539e-07 3.492e-06
206 NEURON PROJECTION DEVELOPMENT 102 545 1.566e-07 3.537e-06
207 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 138 799 1.704e-07 3.831e-06
208 MUSCLE ORGAN DEVELOPMENT 61 277 1.949e-07 4.36e-06
209 REGULATION OF TRANSPORTER ACTIVITY 48 198 1.962e-07 4.368e-06
210 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 101 541 2.037e-07 4.471e-06
211 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 101 541 2.037e-07 4.471e-06
212 REGULATION OF TRANSMEMBRANE TRANSPORT 84 426 2.032e-07 4.471e-06
213 NEGATIVE REGULATION OF CELL ACTIVATION 41 158 2.142e-07 4.679e-06
214 REGULATION OF T CELL PROLIFERATION 39 147 2.248e-07 4.889e-06
215 NEGATIVE REGULATION OF CELL ADHESION 52 223 2.339e-07 5.038e-06
216 NEURON PROJECTION GUIDANCE 49 205 2.332e-07 5.038e-06
217 PLATELET ACTIVATION 38 142 2.515e-07 5.369e-06
218 CELL DEATH 165 1001 2.51e-07 5.369e-06
219 GLAND DEVELOPMENT 79 395 2.548e-07 5.39e-06
220 ACTIVATION OF PROTEIN KINASE ACTIVITY 61 279 2.542e-07 5.39e-06
221 POSITIVE REGULATION OF OSSIFICATION 27 84 2.609e-07 5.492e-06
222 RESPONSE TO ESTROGEN 51 218 2.733e-07 5.728e-06
223 RESPONSE TO BIOTIC STIMULUS 149 886 2.916e-07 6.085e-06
224 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 85 437 3.17e-07 6.585e-06
225 RESPONSE TO ACID CHEMICAL 67 319 3.247e-07 6.715e-06
226 POSITIVE REGULATION OF T CELL PROLIFERATION 29 95 3.297e-07 6.789e-06
227 REGULATION OF CELL MATRIX ADHESION 28 90 3.382e-07 6.933e-06
228 NEURON DEVELOPMENT 121 687 3.483e-07 7.108e-06
229 REGULATION OF BODY FLUID LEVELS 95 506 3.582e-07 7.278e-06
230 POSITIVE REGULATION OF CELL DEVELOPMENT 90 472 3.6e-07 7.284e-06
231 STEM CELL DIFFERENTIATION 46 190 3.64e-07 7.332e-06
232 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 75 372 3.667e-07 7.354e-06
233 RESPONSE TO INTERFERON GAMMA 38 144 3.707e-07 7.403e-06
234 SENSORY ORGAN DEVELOPMENT 93 493 3.811e-07 7.578e-06
235 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 53 233 4.158e-07 8.233e-06
236 AGING 58 264 4.191e-07 8.264e-06
237 REGULATION OF CALCIUM ION TRANSPORT 49 209 4.338e-07 8.481e-06
238 RESPIRATORY SYSTEM DEVELOPMENT 47 197 4.32e-07 8.481e-06
239 POSITIVE REGULATION OF LEUKOCYTE CHEMOTAXIS 26 81 4.456e-07 8.675e-06
240 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 64 303 4.798e-07 9.303e-06
241 CYTOSKELETON ORGANIZATION 141 838 5.936e-07 1.146e-05
242 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 101 554 6.476e-07 1.245e-05
243 ALPHA BETA T CELL DIFFERENTIATION 18 45 6.877e-07 1.313e-05
244 NEGATIVE REGULATION OF SECRETION 47 200 6.885e-07 1.313e-05
245 REPRODUCTION 202 1297 7.719e-07 1.466e-05
246 CYTOKINE PRODUCTION 33 120 7.75e-07 1.466e-05
247 AMEBOIDAL TYPE CELL MIGRATION 39 154 8.216e-07 1.538e-05
248 NEGATIVE REGULATION OF CELL DEATH 145 872 8.232e-07 1.538e-05
249 MODULATION OF SYNAPTIC TRANSMISSION 63 301 8.187e-07 1.538e-05
250 REGULATION OF CYTOSKELETON ORGANIZATION 93 502 8.722e-07 1.623e-05
251 REGULATION OF CYTOKINE BIOSYNTHETIC PROCESS 28 94 9.112e-07 1.689e-05
252 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 103 573 9.926e-07 1.833e-05
253 CARDIAC CHAMBER DEVELOPMENT 37 144 1.066e-06 1.961e-05
254 CELL JUNCTION ORGANIZATION 44 185 1.09e-06 1.996e-05
255 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 59 278 1.124e-06 2.051e-05
256 CELLULAR RESPONSE TO INTERFERON GAMMA 33 122 1.165e-06 2.117e-05
257 RESPONSE TO HORMONE 147 893 1.249e-06 2.261e-05
258 EMBRYONIC ORGAN MORPHOGENESIS 59 279 1.272e-06 2.293e-05
259 LEUKOCYTE CHEMOTAXIS 32 117 1.291e-06 2.32e-05
260 MESENCHYMAL CELL DIFFERENTIATION 35 134 1.367e-06 2.447e-05
261 T CELL DIFFERENTIATION 33 123 1.421e-06 2.534e-05
262 REGULATION OF ORGAN MORPHOGENESIS 53 242 1.436e-06 2.55e-05
263 REGULATION OF LEUKOCYTE CHEMOTAXIS 28 96 1.456e-06 2.576e-05
264 POSITIVE REGULATION OF NEURON DIFFERENTIATION 63 306 1.475e-06 2.591e-05
265 CELLULAR RESPONSE TO ACID CHEMICAL 42 175 1.472e-06 2.591e-05
266 HEART MORPHOGENESIS 48 212 1.649e-06 2.885e-05
267 EXTRACELLULAR MATRIX DISASSEMBLY 24 76 1.701e-06 2.963e-05
268 REGULATION OF BLOOD CIRCULATION 61 295 1.852e-06 3.216e-05
269 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 38 153 1.889e-06 3.267e-05
270 REGULATION OF PHOSPHOLIPASE C ACTIVITY 16 39 1.914e-06 3.298e-05
271 REGULATION OF ION HOMEOSTASIS 46 201 1.971e-06 3.385e-05
272 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 51 232 2.004e-06 3.416e-05
273 REGULATION OF LEUKOCYTE DIFFERENTIATION 51 232 2.004e-06 3.416e-05
274 OSSIFICATION 54 251 2.042e-06 3.467e-05
275 INNATE IMMUNE RESPONSE 108 619 2.328e-06 3.94e-05
276 MESENCHYME DEVELOPMENT 44 190 2.339e-06 3.943e-05
277 REGULATION OF APOPTOTIC SIGNALING PATHWAY 71 363 2.361e-06 3.966e-05
278 MAMMARY GLAND EPITHELIUM DEVELOPMENT 19 53 2.428e-06 4.049e-05
279 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 19 53 2.428e-06 4.049e-05
280 POSITIVE REGULATION OF BLOOD CIRCULATION 27 93 2.459e-06 4.086e-05
281 LYMPHOCYTE DIFFERENTIATION 47 209 2.572e-06 4.26e-05
282 LEUKOCYTE PROLIFERATION 26 88 2.616e-06 4.317e-05
283 REGULATION OF CYTOPLASMIC TRANSPORT 88 481 2.898e-06 4.765e-05
284 ENDOCYTOSIS 92 509 2.939e-06 4.815e-05
285 RESPONSE TO MECHANICAL STIMULUS 47 210 2.957e-06 4.828e-05
286 REGULATION OF LEUKOCYTE MEDIATED IMMUNITY 38 156 3.124e-06 5.083e-05
287 RESPONSE TO GROWTH FACTOR 87 475 3.144e-06 5.097e-05
288 SEMAPHORIN PLEXIN SIGNALING PATHWAY 15 36 3.175e-06 5.13e-05
289 REGULATION OF CELL SHAPE 35 139 3.392e-06 5.462e-05
290 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 48 218 3.774e-06 6.056e-05
291 NEGATIVE REGULATION OF PHOSPHORYLATION 79 422 3.8e-06 6.077e-05
292 MAMMARY GLAND DEVELOPMENT 31 117 3.892e-06 6.202e-05
293 RESPONSE TO ESTRADIOL 36 146 4.166e-06 6.615e-05
294 NEGATIVE REGULATION OF CELL DEVELOPMENT 61 303 4.589e-06 7.263e-05
295 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 34 135 4.629e-06 7.302e-05
296 INTERFERON GAMMA MEDIATED SIGNALING PATHWAY 22 70 4.969e-06 7.811e-05
297 REGULATION OF CELL GROWTH 74 391 5.091e-06 7.975e-05
298 OVULATION CYCLE 30 113 5.302e-06 8.278e-05
299 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 106 616 5.456e-06 8.491e-05
300 REGULATION OF HEART RATE 25 86 5.586e-06 8.664e-05
301 CELL MATRIX ADHESION 31 119 5.695e-06 8.804e-05
302 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 76 406 5.778e-06 8.884e-05
303 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 42 184 5.785e-06 8.884e-05
304 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 37 154 5.896e-06 9.005e-05
305 REGULATION OF CELL SIZE 40 172 5.922e-06 9.005e-05
306 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 159 1008 5.915e-06 9.005e-05
307 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 33 131 6.319e-06 9.577e-05
308 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 44 197 6.385e-06 9.645e-05
309 REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 26 92 6.471e-06 9.745e-05
310 VESICLE MEDIATED TRANSPORT 189 1239 6.841e-06 0.0001027
311 COLLAGEN FIBRIL ORGANIZATION 15 38 7.083e-06 0.000106
312 CELLULAR RESPONSE TO LIPID 83 457 7.327e-06 0.0001089
313 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 27 98 7.307e-06 0.0001089
314 NEGATIVE REGULATION OF CYTOKINE PRODUCTION 46 211 7.85e-06 0.0001163
315 CARDIAC CHAMBER MORPHOGENESIS 28 104 8.076e-06 0.0001181
316 POSITIVE REGULATION OF RESPONSE TO WOUNDING 38 162 8.096e-06 0.0001181
317 POSITIVE REGULATION OF IMMUNE EFFECTOR PROCESS 37 156 8.093e-06 0.0001181
318 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 28 104 8.076e-06 0.0001181
319 REGULATION OF INTERLEUKIN 6 PRODUCTION 28 104 8.076e-06 0.0001181
320 MAMMARY GLAND EPITHELIAL CELL PROLIFERATION 8 12 8.4e-06 0.0001221
321 PROTEIN LOCALIZATION TO MEMBRANE 71 376 8.506e-06 0.0001233
322 RESPONSE TO DRUG 79 431 8.543e-06 0.0001235
323 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 30 116 9.361e-06 0.0001349
324 RESPONSE TO NITROGEN COMPOUND 138 859 9.678e-06 0.000139
325 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 33 134 1.059e-05 0.0001516
326 DEFENSE RESPONSE TO VIRUS 38 164 1.095e-05 0.0001563
327 RHYTHMIC PROCESS 59 298 1.113e-05 0.0001583
328 REGULATION OF VESICLE MEDIATED TRANSPORT 83 462 1.117e-05 0.0001585
329 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 39 171 1.252e-05 0.0001771
330 REGULATION OF HEART CONTRACTION 47 221 1.257e-05 0.0001772
331 REGULATION OF MUSCLE CONTRACTION 35 147 1.285e-05 0.0001801
332 REGULATION OF JNK CASCADE 37 159 1.283e-05 0.0001801
333 RESPONSE TO INTERLEUKIN 4 13 31 1.328e-05 0.0001856
334 CELL PROJECTION ORGANIZATION 143 902 1.346e-05 0.0001869
335 CENTRAL NERVOUS SYSTEM DEVELOPMENT 139 872 1.345e-05 0.0001869
336 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 45 209 1.371e-05 0.0001893
337 REGULATION OF PEPTIDE SECRETION 45 209 1.371e-05 0.0001893
338 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 281 1977 1.384e-05 0.0001905
339 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 79 437 1.432e-05 0.0001966
340 MAMMARY GLAND MORPHOGENESIS 15 40 1.479e-05 0.0002024
341 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 48 229 1.531e-05 0.0002089
342 POSITIVE REGULATION OF INFLAMMATORY RESPONSE 29 113 1.536e-05 0.000209
343 POSITIVE REGULATION OF ION TRANSPORT 49 236 1.638e-05 0.0002222
344 ARTERY DEVELOPMENT 22 75 1.71e-05 0.0002314
345 REGULATION OF CELL PROJECTION ASSEMBLY 36 155 1.745e-05 0.0002354
346 INTERSPECIES INTERACTION BETWEEN ORGANISMS 110 662 1.805e-05 0.000242
347 SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM 110 662 1.805e-05 0.000242
348 REGULATION OF HOMEOSTATIC PROCESS 80 447 1.84e-05 0.0002447
349 RESPONSE TO PROGESTERONE 17 50 1.835e-05 0.0002447
350 RESPONSE TO GAMMA RADIATION 17 50 1.835e-05 0.0002447
351 REGULATION OF AXONOGENESIS 38 168 1.962e-05 0.0002601
352 REGULATION OF LYMPHOCYTE DIFFERENTIATION 32 132 2.016e-05 0.0002665
353 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 33 138 2.04e-05 0.0002681
354 PLACENTA DEVELOPMENT 33 138 2.04e-05 0.0002681
355 LUNG ALVEOLUS DEVELOPMENT 15 41 2.09e-05 0.0002732
356 RECEPTOR CLUSTERING 15 41 2.09e-05 0.0002732
357 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 48 232 2.189e-05 0.0002853
358 T CELL MEDIATED IMMUNITY 12 28 2.196e-05 0.0002854
359 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 26 98 2.224e-05 0.0002882
360 CIRCULATORY SYSTEM PROCESS 68 366 2.255e-05 0.0002912
361 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 45 213 2.266e-05 0.0002912
362 ANTIGEN PROCESSING AND PRESENTATION 45 213 2.266e-05 0.0002912
363 REGULATION OF HORMONE LEVELS 84 478 2.304e-05 0.0002953
364 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 166 1087 2.369e-05 0.0003029
365 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 67 360 2.441e-05 0.0003111
366 GLIAL CELL MIGRATION 14 37 2.526e-05 0.0003211
367 MEMBRANE ORGANIZATION 141 899 2.667e-05 0.0003381
368 RESPONSE TO PURINE CONTAINING COMPOUND 36 158 2.715e-05 0.0003433
369 REGULATION OF SYNAPTIC PLASTICITY 33 140 2.792e-05 0.0003484
370 INTERACTION WITH HOST 32 134 2.783e-05 0.0003484
371 CARDIAC MUSCLE TISSUE DEVELOPMENT 33 140 2.792e-05 0.0003484
372 REGULATION OF STEM CELL PROLIFERATION 24 88 2.773e-05 0.0003484
373 REGULATION OF IMMUNE EFFECTOR PROCESS 76 424 2.793e-05 0.0003484
374 NEGATIVE REGULATION OF TISSUE REMODELING 9 17 3.019e-05 0.0003756
375 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 73 404 3.032e-05 0.0003762
376 SINGLE ORGANISM BEHAVIOR 70 384 3.269e-05 0.0004046
377 APOPTOTIC SIGNALING PATHWAY 56 289 3.476e-05 0.0004279
378 NEGATIVE REGULATION OF GROWTH 48 236 3.471e-05 0.0004279
379 REGULATION OF EPITHELIAL CELL MIGRATION 37 166 3.522e-05 0.0004312
380 AMINOGLYCAN METABOLIC PROCESS 37 166 3.522e-05 0.0004312
381 CHONDROCYTE DEVELOPMENT 10 21 3.54e-05 0.0004323
382 SUBSTRATE ADHESION DEPENDENT CELL SPREADING 14 38 3.586e-05 0.0004357
383 REGULATION OF OSTEOBLAST DIFFERENTIATION 28 112 3.583e-05 0.0004357
384 SECOND MESSENGER MEDIATED SIGNALING 36 160 3.612e-05 0.0004366
385 CELL CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 43 204 3.608e-05 0.0004366
386 EXOCYTOSIS 59 310 3.75e-05 0.000452
387 POSITIVE REGULATION OF PROTEIN SECRETION 44 211 3.871e-05 0.0004654
388 EPITHELIAL CELL DEVELOPMENT 40 186 4.136e-05 0.0004897
389 REGULATION OF EXOCYTOSIS 40 186 4.136e-05 0.0004897
390 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 65 352 4.107e-05 0.0004897
391 T CELL MIGRATION 8 14 4.134e-05 0.0004897
392 PEPTIDYL TYROSINE MODIFICATION 40 186 4.136e-05 0.0004897
393 REGULATION OF MUSCLE ADAPTATION 19 63 4.125e-05 0.0004897
394 REGULATION OF CYTOKINE SECRETION 34 149 4.339e-05 0.0005124
395 POSITIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 31 131 4.446e-05 0.0005217
396 POSITIVE REGULATION OF CYTOKINE SECRETION 25 96 4.451e-05 0.0005217
397 ACTIVATION OF MAPK ACTIVITY 32 137 4.437e-05 0.0005217
398 CARDIAC SEPTUM DEVELOPMENT 23 85 4.63e-05 0.00054
399 POSITIVE REGULATION OF LEUKOCYTE MEDIATED IMMUNITY 23 85 4.63e-05 0.00054
400 CELL PART MORPHOGENESIS 104 633 4.838e-05 0.0005628
401 NEGATIVE REGULATION OF PROTEIN SECRETION 27 108 4.901e-05 0.0005659
402 EPITHELIAL CELL DIFFERENTIATION 85 495 4.878e-05 0.0005659
403 MUCOPOLYSACCHARIDE METABOLIC PROCESS 27 108 4.901e-05 0.0005659
404 BONE TRABECULA MORPHOGENESIS 7 11 5.015e-05 0.0005746
405 NEGATIVE REGULATION OF CELL MATRIX ADHESION 12 30 5.03e-05 0.0005746
406 HETEROCHROMATIN ORGANIZATION 7 11 5.015e-05 0.0005746
407 CELLULAR MACROMOLECULE LOCALIZATION 183 1234 5.038e-05 0.0005746
408 NEGATIVE CHEMOTAXIS 14 39 5.017e-05 0.0005746
409 B CELL ACTIVATION 31 132 5.191e-05 0.0005906
410 REGULATION OF PHOSPHOLIPASE ACTIVITY 19 64 5.252e-05 0.000596
411 POSITIVE REGULATION OF HEMOPOIESIS 36 163 5.469e-05 0.0006177
412 SKELETAL SYSTEM MORPHOGENESIS 42 201 5.462e-05 0.0006177
413 REGULATION OF HEMOPOIESIS 59 314 5.486e-05 0.0006181
414 CELLULAR RESPONSE TO INTERLEUKIN 4 11 26 5.606e-05 0.00063
415 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 26 103 5.626e-05 0.0006308
416 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL 21 75 5.66e-05 0.0006316
417 NEURAL CREST CELL DIFFERENTIATION 21 75 5.66e-05 0.0006316
418 SINGLE ORGANISM CELLULAR LOCALIZATION 139 898 5.765e-05 0.0006418
419 CELLULAR CHEMICAL HOMEOSTASIS 95 570 5.869e-05 0.0006518
420 NEGATIVE REGULATION OF IMMUNE RESPONSE 29 121 6.039e-05 0.000669
421 POSITIVE REGULATION OF HEART CONTRACTION 13 35 6.159e-05 0.0006807
422 IMMUNE RESPONSE REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 60 323 6.693e-05 0.0007379
423 TISSUE REMODELING 23 87 6.875e-05 0.0007563
424 REGULATION OF CALCIUM MEDIATED SIGNALING 21 76 6.999e-05 0.0007671
425 PROTEIN SECRETION 28 116 7.023e-05 0.0007671
426 FEMALE SEX DIFFERENTIATION 28 116 7.023e-05 0.0007671
427 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 18 60 7.047e-05 0.0007679
428 REGULATION OF CELLULAR RESPONSE TO STRESS 111 691 7.122e-05 0.0007743
429 ESTABLISHMENT OF PROTEIN LOCALIZATION 206 1423 7.364e-05 0.0007987
430 MYELOID LEUKOCYTE MIGRATION 25 99 7.701e-05 0.0008333
431 HEMOSTASIS 58 311 7.837e-05 0.000846
432 NEGATIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 31 135 8.156e-05 0.0008784
433 REGULATION OF RECEPTOR ACTIVITY 28 117 8.252e-05 0.0008848
434 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 28 117 8.252e-05 0.0008848
435 OVULATION CYCLE PROCESS 23 88 8.327e-05 0.0008907
436 REGULATION OF CARDIAC MUSCLE CONTRACTION 19 66 8.353e-05 0.0008914
437 HETEROTYPIC CELL CELL ADHESION 11 27 8.499e-05 0.0009049
438 DEVELOPMENTAL CELL GROWTH 21 77 8.613e-05 0.000915
439 ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE OR POLYSACCHARIDE ANTIGEN VIA MHC CLASS II 24 94 8.813e-05 0.0009319
440 ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE ANTIGEN VIA MHC CLASS II 24 94 8.813e-05 0.0009319
441 NEURAL CREST CELL MIGRATION 16 51 9.731e-05 0.001027
442 EPITHELIAL CELL PROLIFERATION 23 89 0.0001004 0.001057
443 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 19 67 0.0001044 0.001097
444 LYMPHOCYTE COSTIMULATION 21 78 0.0001055 0.0011
445 HOMEOSTATIC PROCESS 194 1337 0.0001054 0.0011
446 CANONICAL WNT SIGNALING PATHWAY 24 95 0.0001055 0.0011
447 REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION 25 101 0.0001091 0.001134
448 SKELETAL MUSCLE ORGAN DEVELOPMENT 31 137 0.000109 0.001134
449 CELLULAR HOMEOSTASIS 108 676 0.0001106 0.001146
450 REGULATION OF SEQUESTERING OF CALCIUM ION 26 107 0.0001115 0.001151
451 REGULATION OF T CELL DIFFERENTIATION 26 107 0.0001115 0.001151
452 REGULATION OF TISSUE REMODELING 18 62 0.000113 0.001163
453 GLIOGENESIS 37 175 0.0001143 0.001174
454 POSITIVE REGULATION OF DEFENSE RESPONSE 65 364 0.0001151 0.00118
455 POSITIVE REGULATION OF PROTEIN TYROSINE KINASE ACTIVITY 13 37 0.0001197 0.001221
456 REGULATION OF MUSCLE HYPERTROPHY 13 37 0.0001197 0.001221
457 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 32 144 0.0001223 0.001245
458 RESPONSE TO KETONE 38 182 0.0001228 0.001248
459 MAINTENANCE OF LOCATION 31 138 0.0001257 0.001269
460 TELENCEPHALON DEVELOPMENT 45 228 0.0001257 0.001269
461 MAMMARY GLAND DUCT MORPHOGENESIS 11 28 0.0001258 0.001269
462 REGULATION OF CELL JUNCTION ASSEMBLY 19 68 0.0001297 0.001298
463 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 19 68 0.0001297 0.001298
464 POSITIVE REGULATION OF INTERLEUKIN 6 PRODUCTION 19 68 0.0001297 0.001298
465 NEGATIVE REGULATION OF HOMOTYPIC CELL CELL ADHESION 25 102 0.0001293 0.001298
466 REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY 27 114 0.0001322 0.001317
467 HEAD DEVELOPMENT 112 709 0.000132 0.001317
468 EPHRIN RECEPTOR SIGNALING PATHWAY 22 85 0.0001376 0.001368
469 ION HOMEOSTASIS 94 576 0.0001405 0.001394
470 ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE ANTIGEN 37 177 0.000146 0.001445
471 REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION 41 203 0.0001463 0.001446
472 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 30 133 0.0001482 0.00146
473 SYNAPTIC SIGNALING 73 424 0.0001484 0.00146
474 REGULATION OF INTERFERON GAMMA PRODUCTION 24 97 0.0001495 0.001465
475 EMBRYONIC EYE MORPHOGENESIS 12 33 0.0001494 0.001465
476 NEGATIVE REGULATION OF ION TRANSPORT 29 127 0.0001512 0.001478
477 RESPONSE TO PROTOZOAN 9 20 0.000152 0.00148
478 BRANCHING INVOLVED IN MAMMARY GLAND DUCT MORPHOGENESIS 9 20 0.000152 0.00148
479 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 16 53 0.0001617 0.001568
480 REGULATION OF NITRIC OXIDE BIOSYNTHETIC PROCESS 16 53 0.0001617 0.001568
481 REGULATED EXOCYTOSIS 44 224 0.0001662 0.001607
482 DIGESTIVE TRACT MORPHOGENESIS 15 48 0.0001676 0.001618
483 COGNITION 48 251 0.0001689 0.001623
484 MORPHOGENESIS OF AN EPITHELIAL SHEET 14 43 0.0001687 0.001623
485 POSITIVE REGULATION OF ERK1 AND ERK2 CASCADE 36 172 0.0001736 0.001665
486 ACTIVATION OF GTPASE ACTIVITY 20 75 0.000176 0.001678
487 SENSORY PERCEPTION OF PAIN 20 75 0.000176 0.001678
488 RESPONSE TO BACTERIUM 87 528 0.000176 0.001678
489 REGULATION OF ERK1 AND ERK2 CASCADE 46 238 0.0001771 0.001682
490 POSITIVE REGULATION OF GROWTH 46 238 0.0001771 0.001682
491 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION 26 110 0.0001807 0.001712
492 CARTILAGE DEVELOPMENT 32 147 0.0001834 0.001734
493 POSITIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 37 179 0.0001854 0.00175
494 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 65 370 0.0001866 0.001754
495 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 127 829 0.0001864 0.001754
496 VASCULOGENESIS 17 59 0.0001922 0.001803
497 SEX DIFFERENTIATION 50 266 0.0001935 0.001812
498 MOVEMENT IN ENVIRONMENT OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 22 87 0.0001982 0.001819
499 ENTRY INTO CELL OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 22 87 0.0001982 0.001819
500 STRIATED MUSCLE CELL DIFFERENTIATION 36 173 0.0001958 0.001819
501 REGULATION OF PROTEIN POLYMERIZATION 36 173 0.0001958 0.001819
502 VIRAL ENTRY INTO HOST CELL 22 87 0.0001982 0.001819
503 ENTRY INTO OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 22 87 0.0001982 0.001819
504 MOVEMENT IN HOST ENVIRONMENT 22 87 0.0001982 0.001819
505 SENSORY ORGAN MORPHOGENESIS 46 239 0.0001958 0.001819
506 ENTRY INTO HOST 22 87 0.0001982 0.001819
507 ENTRY INTO HOST CELL 22 87 0.0001982 0.001819
508 MULTICELLULAR ORGANISM METABOLIC PROCESS 23 93 0.000205 0.001877
509 REGULATION OF ADAPTIVE IMMUNE RESPONSE 28 123 0.000206 0.001883
510 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 24 99 0.0002092 0.001908
511 SEMAPHORIN PLEXIN SIGNALING PATHWAY INVOLVED IN NEURON PROJECTION GUIDANCE 7 13 0.0002124 0.00193
512 EXTRACELLULAR FIBRIL ORGANIZATION 7 13 0.0002124 0.00193
513 REGULATION OF TRANSFORMING GROWTH FACTOR BETA PRODUCTION 10 25 0.0002144 0.001945
514 CELLULAR RESPONSE TO RETINOIC ACID 18 65 0.0002188 0.00198
515 REGULATION OF AXON GUIDANCE 13 39 0.0002198 0.001982
516 POSITIVE REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 13 39 0.0002198 0.001982
517 ACTIN FILAMENT ORGANIZATION 36 174 0.0002206 0.001985
518 POSITIVE REGULATION OF MUSCLE CONTRACTION 14 44 0.000222 0.001994
519 NEGATIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 30 136 0.000225 0.002017
520 CELL FATE COMMITMENT 44 227 0.0002265 0.002026
521 REGULATION OF REGULATED SECRETORY PATHWAY 29 130 0.0002319 0.002067
522 CONNECTIVE TISSUE DEVELOPMENT 39 194 0.0002317 0.002067
523 ION TRANSPORT 182 1262 0.0002374 0.002112
524 REGULATION OF MONOOXYGENASE ACTIVITY 17 60 0.0002403 0.002134
525 POSITIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 34 162 0.0002454 0.002175
526 REGULATION OF FAT CELL DIFFERENTIATION 25 106 0.0002471 0.002178
527 CARDIAC VENTRICLE DEVELOPMENT 25 106 0.0002471 0.002178
528 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 24 100 0.0002462 0.002178
529 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 49 262 0.0002523 0.002219
530 EAR DEVELOPMENT 39 195 0.0002587 0.002263
531 REGULATION OF DENDRITIC SPINE MORPHOGENESIS 11 30 0.0002584 0.002263
532 OSTEOCLAST DIFFERENTIATION 11 30 0.0002584 0.002263
533 REGULATION OF KIDNEY DEVELOPMENT 16 55 0.0002605 0.002269
534 CRANIAL SKELETAL SYSTEM DEVELOPMENT 16 55 0.0002605 0.002269
535 REGULATION OF BINDING 52 283 0.0002609 0.002269
536 REGULATION OF BLOOD PRESSURE 35 169 0.0002624 0.002278
537 REGULATION OF PROTEIN COMPLEX ASSEMBLY 65 375 0.0002748 0.002381
538 MYELOID CELL DIFFERENTIATION 38 189 0.0002759 0.002386
539 POSITIVE REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 15 50 0.0002775 0.002396
540 POSITIVE REGULATION OF CAMP METABOLIC PROCESS 22 89 0.0002812 0.002423
541 NEGATIVE REGULATION OF DEFENSE RESPONSE 31 144 0.0002825 0.002429
542 EYE DEVELOPMENT 58 326 0.000288 0.002473
543 REGULATION OF EXTENT OF CELL GROWTH 24 101 0.000289 0.002476
544 REGULATION OF FILOPODIUM ASSEMBLY 13 40 0.0002923 0.0025
545 POSITIVE REGULATION OF STEM CELL PROLIFERATION 17 61 0.0002986 0.002549
546 ACTIVATION OF IMMUNE RESPONSE 72 427 0.0003103 0.002645
547 REGULATION OF T HELPER CELL DIFFERENTIATION 10 26 0.0003134 0.002661
548 NEGATIVE REGULATION OF EMBRYONIC DEVELOPMENT 10 26 0.0003134 0.002661
549 REGULATION OF DENDRITE DEVELOPMENT 27 120 0.0003238 0.002744
550 REGULATION OF SYSTEMIC ARTERIAL BLOOD PRESSURE 21 84 0.0003246 0.002746
551 REGULATION OF DENDRITIC SPINE DEVELOPMENT 16 56 0.0003269 0.002761
552 NEGATIVE REGULATION OF GENE EXPRESSION 210 1493 0.0003286 0.00277
553 REGULATION OF ENDOTHELIAL CELL MIGRATION 26 114 0.0003308 0.002783
554 RESPONSE TO ORGANOPHOSPHORUS 30 139 0.0003353 0.002816
555 MYELOID LEUKOCYTE DIFFERENTIATION 23 96 0.0003374 0.002828
556 REGULATION OF PROTEIN TARGETING 55 307 0.0003414 0.002857
557 ARTERY MORPHOGENESIS 15 51 0.0003526 0.002935
558 NEGATIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 15 51 0.0003526 0.002935
559 HOMOTYPIC CELL CELL ADHESION 15 51 0.0003526 0.002935
560 FOREBRAIN DEVELOPMENT 62 357 0.0003559 0.002957
561 POSITIVE REGULATION OF MUSCLE HYPERTROPHY 9 22 0.0003649 0.003021
562 POSITIVE REGULATION OF CARDIAC MUSCLE HYPERTROPHY 9 22 0.0003649 0.003021
563 MULTICELLULAR ORGANISMAL MACROMOLECULE METABOLIC PROCESS 20 79 0.0003734 0.003059
564 REGULATION OF STRIATED MUSCLE CONTRACTION 20 79 0.0003734 0.003059
565 PEPTIDYL THREONINE MODIFICATION 14 46 0.0003729 0.003059
566 REGULATION OF ALPHA BETA T CELL DIFFERENTIATION 14 46 0.0003729 0.003059
567 NEGATIVE REGULATION OF CYTOKINE SECRETION 14 46 0.0003729 0.003059
568 EMBRYONIC CRANIAL SKELETON MORPHOGENESIS 14 46 0.0003729 0.003059
569 T CELL SELECTION 12 36 0.0003818 0.003122
570 REGULATION OF NEURON APOPTOTIC PROCESS 38 192 0.0003826 0.003123
571 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 13 41 0.0003842 0.003126
572 AORTA DEVELOPMENT 13 41 0.0003842 0.003126
573 WNT SIGNALING PATHWAY 61 351 0.000388 0.00315
574 POSITIVE REGULATION OF CATION TRANSMEMBRANE TRANSPORT 23 97 0.0003958 0.003203
575 NEUROMUSCULAR PROCESS 23 97 0.0003958 0.003203
576 CELLULAR COMPONENT MAINTENANCE 8 18 0.0003973 0.003204
577 UTERUS DEVELOPMENT 8 18 0.0003973 0.003204
578 REGULATION OF ALPHA BETA T CELL ACTIVATION 18 68 0.0004023 0.003238
579 CELL DIVISION 76 460 0.0004038 0.003245
580 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 27 122 0.0004281 0.003423
581 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 27 122 0.0004281 0.003423
582 NEGATIVE REGULATION OF HORMONE SECRETION 19 74 0.0004278 0.003423
583 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 42 220 0.0004325 0.003452
584 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 212 1517 0.0004385 0.003494
585 ADAPTIVE IMMUNE RESPONSE BASED ON SOMATIC RECOMBINATION OF IMMUNE RECEPTORS BUILT FROM IMMUNOGLOBULIN SUPERFAMILY DOMAINS 32 154 0.0004425 0.00352
586 ACTIVATION OF PHOSPHOLIPASE C ACTIVITY 10 27 0.0004478 0.003532
587 NEGATIVE REGULATION OF VASCULATURE DEVELOPMENT 20 80 0.0004459 0.003532
588 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 10 27 0.0004478 0.003532
589 SUBSTRATE DEPENDENT CELL MIGRATION 10 27 0.0004478 0.003532
590 CELLULAR RESPONSE TO MECHANICAL STIMULUS 20 80 0.0004459 0.003532
591 REGULATION OF CELL KILLING 17 63 0.0004525 0.003563
592 MYELOID LEUKOCYTE ACTIVATION 23 98 0.0004628 0.003638
593 POSITIVE REGULATION OF CELL CYCLE 58 332 0.0004649 0.003648
594 DIGESTIVE SYSTEM DEVELOPMENT 31 148 0.0004668 0.003655
595 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 113 740 0.0004674 0.003655
596 TUBE FORMATION 28 129 0.0004725 0.003683
597 CELL JUNCTION ASSEMBLY 28 129 0.0004725 0.003683
598 REGULATION OF MULTI ORGANISM PROCESS 77 470 0.0004804 0.003738
599 NEGATIVE REGULATION OF OSSIFICATION 18 69 0.0004876 0.003782
600 SYNAPSE ASSEMBLY 18 69 0.0004876 0.003782
601 NEGATIVE REGULATION OF GTPASE ACTIVITY 13 42 0.0004996 0.003868
602 POSITIVE REGULATION OF CYTOKINE BIOSYNTHETIC PROCESS 16 58 0.0005045 0.0039
603 GRANULOCYTE MIGRATION 19 75 0.0005133 0.003961
604 POSITIVE REGULATION OF CYTOSKELETON ORGANIZATION 35 175 0.0005208 0.004012
605 REGULATION OF JUN KINASE ACTIVITY 20 81 0.0005303 0.004078
606 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 23 99 0.0005396 0.004118
607 RESPONSE TO AUDITORY STIMULUS 9 23 0.0005398 0.004118
608 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 23 99 0.0005396 0.004118
609 TRABECULA FORMATION 9 23 0.0005398 0.004118
610 RENAL SYSTEM PROCESS INVOLVED IN REGULATION OF SYSTEMIC ARTERIAL BLOOD PRESSURE 9 23 0.0005398 0.004118
611 CHEMICAL HOMEOSTASIS 130 874 0.0005428 0.004134
612 POSITIVE REGULATION OF PHOSPHOLIPASE ACTIVITY 15 53 0.0005561 0.004221
613 POSITIVE REGULATION OF FIBROBLAST PROLIFERATION 15 53 0.0005561 0.004221
614 REGULATION OF ACTIN FILAMENT LENGTH 32 156 0.0005606 0.004234
615 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 32 156 0.0005606 0.004234
616 NEGATIVE REGULATION OF RESPONSE TO WOUNDING 32 156 0.0005606 0.004234
617 REGULATION OF VENTRICULAR CARDIAC MUSCLE CELL ACTION POTENTIAL 6 11 0.0005697 0.004269
618 POSITIVE REGULATION OF MACROPHAGE CHEMOTAXIS 6 11 0.0005697 0.004269
619 CD4 POSITIVE OR CD8 POSITIVE ALPHA BETA T CELL LINEAGE COMMITMENT 6 11 0.0005697 0.004269
620 CYCLOOXYGENASE PATHWAY 6 11 0.0005697 0.004269
621 CELL CYCLE 186 1316 0.0005676 0.004269
622 RESPONSE TO CORTICOSTEROID 35 176 0.0005809 0.004346
623 RESPONSE TO ALKALOID 29 137 0.0005844 0.004364
624 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 18 70 0.0005882 0.004386
625 VASCULAR PROCESS IN CIRCULATORY SYSTEM 33 163 0.0005918 0.004406
626 REGULATION OF NF KAPPAB IMPORT INTO NUCLEUS 14 48 0.0006039 0.004483
627 REGULATION OF PROTEIN IMPORT 36 183 0.000604 0.004483
628 REGULATION OF INFLAMMATORY RESPONSE TO ANTIGENIC STIMULUS 8 19 0.0006187 0.00457
629 FIBRIL ORGANIZATION 8 19 0.0006187 0.00457
630 ESTROUS CYCLE 8 19 0.0006187 0.00457
631 REGULATION OF FIBROBLAST MIGRATION 10 28 0.0006267 0.004603
632 NEGATIVE REGULATION OF CYTOKINE BIOSYNTHETIC PROCESS 10 28 0.0006267 0.004603
633 NEGATIVE REGULATION OF INFLAMMATORY RESPONSE 23 100 0.0006272 0.004603
634 DIVALENT INORGANIC CATION HOMEOSTASIS 59 343 0.0006244 0.004603
635 KIDNEY MORPHOGENESIS 20 82 0.0006281 0.004603
636 NEURAL TUBE FORMATION 22 94 0.0006339 0.004636
637 REGULATION OF CATION CHANNEL ACTIVITY 21 88 0.0006346 0.004636
638 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 62 365 0.0006447 0.004694
639 RECEPTOR MEDIATED ENDOCYTOSIS 43 231 0.0006446 0.004694
640 INTERFERON GAMMA PRODUCTION 7 15 0.000649 0.004711
641 NEGATIVE REGULATION OF INTERLEUKIN 12 PRODUCTION 7 15 0.000649 0.004711
642 NEGATIVE REGULATION OF CELL CELL ADHESION 29 138 0.0006616 0.004786
643 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 110 724 0.0006643 0.004786
644 POSITIVE REGULATION OF HORMONE SECRETION 26 119 0.0006658 0.004786
645 REGULATION OF CD4 POSITIVE ALPHA BETA T CELL ACTIVATION 12 38 0.0006665 0.004786
646 REGULATION OF ACTION POTENTIAL 12 38 0.0006665 0.004786
647 CYTOKINE SECRETION 12 38 0.0006665 0.004786
648 REGULATION OF NEURON DEATH 46 252 0.0006624 0.004786
649 REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 17 65 0.0006705 0.0048
650 POSITIVE REGULATION OF INTERFERON GAMMA PRODUCTION 17 65 0.0006705 0.0048
651 CELLULAR RESPONSE TO NITROGEN COMPOUND 81 505 0.000673 0.00481
652 SKIN DEVELOPMENT 40 211 0.0006748 0.004815
653 RESPONSE TO IONIZING RADIATION 30 145 0.0007075 0.005041
654 NEGATIVE REGULATION OF PROTEIN COMPLEX ASSEMBLY 24 107 0.0007102 0.005045
655 RESPONSE TO RETINOIC ACID 24 107 0.0007102 0.005045
656 EMBRYONIC PLACENTA DEVELOPMENT 20 83 0.0007412 0.005249
657 PROTEOGLYCAN METABOLIC PROCESS 20 83 0.0007412 0.005249
658 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 31 152 0.0007502 0.005305
659 T CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE 16 60 0.0007591 0.005335
660 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 14 49 0.0007588 0.005335
661 LYMPHOCYTE MIGRATION 14 49 0.0007588 0.005335
662 CARDIAC SEPTUM MORPHOGENESIS 14 49 0.0007588 0.005335
663 REGULATION OF WNT SIGNALING PATHWAY 54 310 0.0007667 0.005372
664 PROTEIN AUTOPHOSPHORYLATION 37 192 0.0007665 0.005372
665 CARDIAC EPITHELIAL TO MESENCHYMAL TRANSITION 9 24 0.0007779 0.005443
666 POSITIVE REGULATION OF PURINE NUCLEOTIDE METABOLIC PROCESS 28 133 0.0007878 0.005496
667 POSITIVE REGULATION OF NUCLEOTIDE METABOLIC PROCESS 28 133 0.0007878 0.005496
668 REGULATION OF VASOCONSTRICTION 17 66 0.0008096 0.005639
669 HOMOPHILIC CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 31 153 0.0008412 0.005851
670 MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL 12 39 0.000865 0.005956
671 REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 10 29 0.0008608 0.005956
672 POSITIVE REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 10 29 0.0008608 0.005956
673 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 26 121 0.0008665 0.005956
674 T CELL DIFFERENTIATION INVOLVED IN IMMUNE RESPONSE 10 29 0.0008608 0.005956
675 REGULATION OF B CELL ACTIVATION 26 121 0.0008665 0.005956
676 PLATELET AGGREGATION 12 39 0.000865 0.005956
677 EMBRYO IMPLANTATION 12 39 0.000865 0.005956
678 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 20 84 0.0008714 0.00598
679 REGULATION OF MESENCHYMAL CELL PROLIFERATION 11 34 0.0008838 0.006047
680 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 39 207 0.0008837 0.006047
681 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 75 465 0.0008894 0.006077
682 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 25 115 0.0009036 0.006156
683 NEPHRON DEVELOPMENT 25 115 0.0009036 0.006156
684 REGULATION OF PROTEIN TYROSINE KINASE ACTIVITY 16 61 0.0009228 0.006268
685 OVARIAN FOLLICLE DEVELOPMENT 16 61 0.0009228 0.006268
686 PARTURITION 8 20 0.0009298 0.006298
687 RESPONSE TO MUSCLE ACTIVITY 8 20 0.0009298 0.006298
688 POSITIVE REGULATION OF CYCLIC NUCLEOTIDE METABOLIC PROCESS 24 109 0.0009379 0.006343
689 POSITIVE REGULATION OF PEPTIDASE ACTIVITY 31 154 0.0009417 0.006359
690 STAT CASCADE 14 50 0.0009459 0.00637
691 JAK STAT CASCADE 14 50 0.0009459 0.00637
692 REGULATION OF CALCIUM ION IMPORT 23 103 0.0009683 0.006511
693 CELL GROWTH 28 135 0.001005 0.006749
694 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 43 236 0.001011 0.00678
695 NEGATIVE REGULATION OF KINASE ACTIVITY 45 250 0.001017 0.00681
696 REGULATION OF GLOMERULAR FILTRATION 6 12 0.001031 0.006881
697 EMBRYONIC CAMERA TYPE EYE FORMATION 6 12 0.001031 0.006881
698 EXOCRINE SYSTEM DEVELOPMENT 13 45 0.001035 0.0069
699 REGULATION OF MONONUCLEAR CELL MIGRATION 7 16 0.001042 0.006926
700 REGULATION OF MACROPHAGE CHEMOTAXIS 7 16 0.001042 0.006926
701 EPITHELIAL TO MESENCHYMAL TRANSITION 15 56 0.001044 0.006931
702 REGULATION OF CYCLIC NUCLEOTIDE METABOLIC PROCESS 31 155 0.001052 0.006976
703 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 27 129 0.001062 0.007027
704 FORMATION OF PRIMARY GERM LAYER 24 110 0.001074 0.007097
705 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 40 216 0.001081 0.007131
706 CELLULAR EXTRAVASATION 9 25 0.001095 0.007216
707 MUSCLE CELL DIFFERENTIATION 43 237 0.001104 0.007263
708 REGULATION OF ACTIVATED T CELL PROLIFERATION 12 40 0.00111 0.007287
709 ENDODERMAL CELL DIFFERENTIATION 12 40 0.00111 0.007287
710 CARDIAC VENTRICLE MORPHOGENESIS 16 62 0.001116 0.007301
711 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 16 62 0.001116 0.007301
712 NEURAL TUBE DEVELOPMENT 30 149 0.001123 0.007341
713 POSITIVE REGULATION OF SMOOTH MUSCLE CONTRACTION 10 30 0.001162 0.007546
714 MODULATION OF EXCITATORY POSTSYNAPTIC POTENTIAL 10 30 0.001162 0.007546
715 RESPONSE TO ATP 10 30 0.001162 0.007546
716 REGULATION OF NEUROLOGICAL SYSTEM PROCESS 17 68 0.001163 0.007546
717 RESPONSE TO X RAY 10 30 0.001162 0.007546
718 NEGATIVE REGULATION OF CHEMOTAXIS 14 51 0.00117 0.007574
719 REGULATION OF INTERLEUKIN 12 PRODUCTION 14 51 0.00117 0.007574
720 BONE DEVELOPMENT 31 156 0.001174 0.00759
721 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 63 381 0.001181 0.007623
722 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 18 74 0.001189 0.007662
723 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 20 86 0.001192 0.007668
724 CELLULAR RESPONSE TO BIOTIC STIMULUS 32 163 0.00122 0.007842
725 POSITIVE REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION 15 57 0.001272 0.008161
726 GLYCOPROTEIN METABOLIC PROCESS 59 353 0.00128 0.008206
727 RESPONSE TO INORGANIC SUBSTANCE 76 479 0.001318 0.008433
728 REGULATION OF CARTILAGE DEVELOPMENT 16 63 0.001341 0.008549
729 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 29 144 0.001341 0.008549
730 POSITIVE REGULATION OF JUN KINASE ACTIVITY 16 63 0.001341 0.008549
731 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 36 191 0.001353 0.008562
732 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 21 93 0.001358 0.008562
733 POSITIVE REGULATION OF TRANSMEMBRANE TRANSPORT 27 131 0.001351 0.008562
734 DECIDUALIZATION 8 21 0.001355 0.008562
735 NEPHRON EPITHELIUM DEVELOPMENT 21 93 0.001358 0.008562
736 TETRAHYDROFOLATE METABOLIC PROCESS 8 21 0.001355 0.008562
737 POSITIVE T CELL SELECTION 8 21 0.001355 0.008562
738 COCHLEA MORPHOGENESIS 8 21 0.001355 0.008562
739 NEGATIVE REGULATION OF LEUKOCYTE PROLIFERATION 17 69 0.001383 0.008699
740 POSITIVE REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY 17 69 0.001383 0.008699
741 RESPONSE TO AMINO ACID 24 112 0.001397 0.008772
742 POSITIVE REGULATION OF KIDNEY DEVELOPMENT 12 41 0.001411 0.008788
743 NEGATIVE REGULATION OF G PROTEIN COUPLED RECEPTOR PROTEIN SIGNALING PATHWAY 12 41 0.001411 0.008788
744 REGULATION OF B CELL MEDIATED IMMUNITY 12 41 0.001411 0.008788
745 POSITIVE REGULATION OF MYELOID CELL DIFFERENTIATION 19 81 0.001402 0.008788
746 CELL SUBSTRATE JUNCTION ASSEMBLY 12 41 0.001411 0.008788
747 MONOCYTE CHEMOTAXIS 12 41 0.001411 0.008788
748 KIDNEY EPITHELIUM DEVELOPMENT 26 125 0.00143 0.008895
749 NEUROMUSCULAR JUNCTION DEVELOPMENT 11 36 0.001501 0.009312
750 T CELL PROLIFERATION 11 36 0.001501 0.009312
751 REGULATION OF CELLULAR SENESCENCE 9 26 0.001509 0.009347
752 CELL CYCLE PHASE TRANSITION 45 255 0.001539 0.009513
753 REGULATION OF INTERLEUKIN 1 PRODUCTION 15 58 0.001539 0.009513
754 L ALPHA AMINO ACID TRANSMEMBRANE TRANSPORT 10 31 0.001544 0.009528
755 INTRINSIC APOPTOTIC SIGNALING PATHWAY 30 152 0.001562 0.009624
756 ACTION POTENTIAL 21 94 0.001566 0.00964
757 CYCLIC NUCLEOTIDE CATABOLIC PROCESS 7 17 0.0016 0.009795
758 NEGATIVE REGULATION OF GLUCOSE TRANSPORT 7 17 0.0016 0.009795
759 MAMMARY GLAND ALVEOLUS DEVELOPMENT 7 17 0.0016 0.009795
760 MAMMARY GLAND LOBULE DEVELOPMENT 7 17 0.0016 0.009795
761 NEGATIVE REGULATION OF LEUKOCYTE MEDIATED IMMUNITY 13 47 0.001609 0.009838
NumGOOverlapSizeP ValueAdj. P Value
1 RECEPTOR BINDING 285 1476 3.74e-21 3.475e-18
2 ENZYME BINDING 298 1737 1.206e-14 5.601e-12
3 PROTEIN COMPLEX BINDING 180 935 1.855e-13 5.745e-11
4 MACROMOLECULAR COMPLEX BINDING 245 1399 4.116e-13 9.56e-11
5 CELL ADHESION MOLECULE BINDING 57 186 7.089e-13 1.317e-10
6 KINASE BINDING 128 606 9.916e-13 1.535e-10
7 MOLECULAR FUNCTION REGULATOR 229 1353 8.025e-11 1.01e-08
8 INTEGRIN BINDING 37 105 8.694e-11 1.01e-08
9 IDENTICAL PROTEIN BINDING 208 1209 1.502e-10 1.55e-08
10 CYTOSKELETAL PROTEIN BINDING 148 819 2.941e-09 2.732e-07
11 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 74 328 3.362e-09 2.839e-07
12 CALCIUM ION BINDING 130 697 3.848e-09 2.979e-07
13 KINASE ACTIVITY 149 842 1.094e-08 7.817e-07
14 ACTIN BINDING 82 393 2.204e-08 1.463e-06
15 RHO GTPASE BINDING 27 78 4.584e-08 2.839e-06
16 GTPASE BINDING 65 295 7.675e-08 4.456e-06
17 REGULATORY REGION NUCLEIC ACID BINDING 142 818 8.225e-08 4.495e-06
18 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 115 629 9.361e-08 4.577e-06
19 G PROTEIN COUPLED RECEPTOR BINDING 59 259 8.928e-08 4.577e-06
20 RIBONUCLEOTIDE BINDING 280 1860 1.136e-07 5.279e-06
21 DOUBLE STRANDED DNA BINDING 133 764 1.811e-07 8.01e-06
22 CALMODULIN BINDING 44 179 4.123e-07 1.741e-05
23 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 26 81 4.456e-07 1.8e-05
24 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 65 315 9.316e-07 3.606e-05
25 ADENYL NUCLEOTIDE BINDING 229 1514 1.296e-06 4.817e-05
26 GROWTH FACTOR BINDING 33 123 1.421e-06 5.078e-05
27 PROTEIN HOMODIMERIZATION ACTIVITY 123 722 1.653e-06 5.688e-05
28 CYTOKINE BINDING 27 92 1.953e-06 6.256e-05
29 RAC GTPASE BINDING 16 39 1.914e-06 6.256e-05
30 PROTEIN KINASE ACTIVITY 111 640 2.257e-06 6.99e-05
31 FIBRONECTIN BINDING 13 28 3.343e-06 0.0001002
32 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 158 992 3.623e-06 0.0001052
33 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 21 64 3.764e-06 0.000106
34 ACTIN FILAMENT BINDING 31 121 8.238e-06 0.0002251
35 PROTEIN DOMAIN SPECIFIC BINDING 106 624 9.752e-06 0.0002588
36 ION CHANNEL BINDING 29 111 1.06e-05 0.0002661
37 CYTOKINE RECEPTOR BINDING 55 271 1.035e-05 0.0002661
38 PHOSPHOLIPID BINDING 68 360 1.293e-05 0.0003161
39 GLYCOSAMINOGLYCAN BINDING 44 205 1.846e-05 0.0004397
40 SEQUENCE SPECIFIC DNA BINDING 160 1037 1.912e-05 0.000444
41 CYTOKINE ACTIVITY 46 219 2.157e-05 0.0004888
42 ENZYME ACTIVATOR ACTIVITY 83 471 2.318e-05 0.0005009
43 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 47 226 2.31e-05 0.0005009
44 EXTRACELLULAR MATRIX BINDING 17 51 2.466e-05 0.0005206
45 PROTEIN TYROSINE KINASE ACTIVITY 39 176 2.527e-05 0.0005218
46 CYTOKINE RECEPTOR ACTIVITY 24 89 3.396e-05 0.0006858
47 BINDING BRIDGING 38 173 3.914e-05 0.0007735
48 METALLOENDOPEPTIDASE ACTIVITY 28 113 4.258e-05 0.000824
49 CHANNEL REGULATOR ACTIVITY 31 131 4.446e-05 0.0008428
50 VIRUS RECEPTOR ACTIVITY 20 70 6.17e-05 0.001126
51 NUCLEOSIDE TRIPHOSPHATASE REGULATOR ACTIVITY 61 329 6.182e-05 0.001126
52 CORE PROMOTER PROXIMAL REGION DNA BINDING 67 371 6.419e-05 0.001147
53 CORE PROMOTER BINDING 34 152 6.648e-05 0.001165
54 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 57 303 7.034e-05 0.00121
55 PROTEIN DIMERIZATION ACTIVITY 171 1149 7.384e-05 0.001247
56 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 26 105 7.971e-05 0.001322
57 ENZYME REGULATOR ACTIVITY 146 959 8.525e-05 0.001389
58 EPHRIN RECEPTOR ACTIVITY 9 19 9.29e-05 0.001488
59 PHOSPHATIDYLINOSITOL BINDING 41 200 0.0001041 0.001639
60 PHOSPHATASE BINDING 35 162 0.0001101 0.001705
61 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 45 228 0.0001257 0.001914
62 TRANSFORMING GROWTH FACTOR BETA BINDING 8 16 0.0001438 0.002092
63 OXIDOREDUCTASE ACTIVITY ACTING ON NAD P H OXYGEN AS ACCEPTOR 8 16 0.0001438 0.002092
64 SIGNALING ADAPTOR ACTIVITY 20 74 0.0001441 0.002092
65 RECEPTOR ACTIVITY 232 1649 0.0001566 0.002238
66 GROWTH FACTOR RECEPTOR BINDING 29 129 0.0002016 0.002837
67 CLATHRIN BINDING 18 65 0.0002188 0.003033
68 SIGNAL TRANSDUCER ACTIVITY 241 1731 0.0002222 0.003036
69 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 35 168 0.0002329 0.003136
70 SH3 SH2 ADAPTOR ACTIVITY 15 52 0.0004445 0.005899
71 SUPEROXIDE GENERATING NADPH OXIDASE ACTIVITY 6 11 0.0005697 0.007351
72 SEMAPHORIN RECEPTOR ACTIVITY 6 11 0.0005697 0.007351
73 CHEMOKINE ACTIVITY 14 48 0.0006039 0.007685
74 PROTEIN SERINE THREONINE KINASE ACTIVITY 73 445 0.0006391 0.008023
75 PROTEIN PHOSPHATASE BINDING 26 120 0.0007604 0.009419
76 EPHRIN RECEPTOR BINDING 9 24 0.0007779 0.009509
77 PROTEIN C TERMINUS BINDING 36 186 0.000825 0.009953
NumGOOverlapSizeP ValueAdj. P Value
1 INTRINSIC COMPONENT OF PLASMA MEMBRANE 330 1649 2.202e-27 1.286e-24
2 CELL JUNCTION 243 1151 2.4e-23 7.009e-21
3 MEMBRANE REGION 228 1134 3.778e-19 7.355e-17
4 NEURON PROJECTION 192 942 7.251e-17 1.059e-14
5 PLASMA MEMBRANE PROTEIN COMPLEX 123 510 1.036e-16 1.211e-14
6 NEURON PART 238 1265 2.574e-16 2.505e-14
7 CELL SURFACE 158 757 5.681e-15 4.74e-13
8 SYNAPSE 155 754 3.99e-14 2.913e-12
9 CELL PROJECTION 301 1786 8.89e-14 5.769e-12
10 PLASMA MEMBRANE REGION 180 929 1.014e-13 5.923e-12
11 EXTRACELLULAR MATRIX 101 426 1.892e-13 1.004e-11
12 RECEPTOR COMPLEX 84 327 2.09e-13 1.017e-11
13 MEMBRANE MICRODOMAIN 77 288 2.293e-13 1.03e-11
14 PROTEINACEOUS EXTRACELLULAR MATRIX 88 356 5.863e-13 2.446e-11
15 SYNAPSE PART 129 610 7.367e-13 2.868e-11
16 ANCHORING JUNCTION 108 489 3.481e-12 1.271e-10
17 CELL PROJECTION PART 177 946 3.88e-12 1.333e-10
18 VACUOLE 210 1180 5.012e-12 1.626e-10
19 ENDOSOME 152 793 2.192e-11 6.737e-10
20 PLASMA MEMBRANE RECEPTOR COMPLEX 52 175 2.61e-11 7.622e-10
21 BASOLATERAL PLASMA MEMBRANE 58 211 6.21e-11 1.727e-09
22 POSTSYNAPSE 86 378 1.158e-10 3.074e-09
23 INTRACELLULAR VESICLE 215 1259 1.425e-10 3.619e-09
24 AXON 92 418 1.711e-10 4.163e-09
25 ACTIN CYTOSKELETON 95 444 4.28e-10 9.999e-09
26 GOLGI APPARATUS 238 1445 4.747e-10 1.066e-08
27 SOMATODENDRITIC COMPARTMENT 126 650 5.763e-10 1.246e-08
28 CYTOPLASMIC REGION 69 287 6.712e-10 1.4e-08
29 MAIN AXON 25 58 7.411e-10 1.492e-08
30 EXCITATORY SYNAPSE 53 197 9.55e-10 1.859e-08
31 AXON PART 56 219 2.504e-09 4.718e-08
32 SIDE OF MEMBRANE 90 428 3.061e-09 5.585e-08
33 CELL SUBSTRATE JUNCTION 85 398 3.891e-09 6.887e-08
34 DENDRITE 93 451 4.706e-09 8.083e-08
35 CELL LEADING EDGE 77 350 5.343e-09 8.915e-08
36 FILOPODIUM 31 94 1.759e-08 2.854e-07
37 EXTRACELLULAR MATRIX COMPONENT 37 125 2.073e-08 3.272e-07
38 CELL CORTEX 56 238 5.887e-08 9.048e-07
39 GOLGI APPARATUS PART 152 893 1.027e-07 1.538e-06
40 VACUOLAR PART 124 694 1.112e-07 1.623e-06
41 ENDOCYTIC VESICLE 58 256 1.395e-07 1.988e-06
42 ENDOSOMAL PART 85 430 1.539e-07 2.14e-06
43 CELL BODY 94 494 2.194e-07 2.98e-06
44 CELL CELL JUNCTION 77 383 2.897e-07 3.845e-06
45 VACUOLAR MEMBRANE 107 587 3.048e-07 3.956e-06
46 EXTERNAL SIDE OF PLASMA MEMBRANE 54 238 3.539e-07 4.493e-06
47 PLASMA MEMBRANE RAFT 27 86 4.447e-07 5.526e-06
48 ACTIN BASED CELL PROJECTION 44 181 5.74e-07 6.984e-06
49 GOLGI MEMBRANE 122 703 6.915e-07 8.242e-06
50 LYTIC VACUOLE 96 526 1.161e-06 1.356e-05
51 PROTEIN COMPLEX INVOLVED IN CELL ADHESION 14 30 1.293e-06 1.481e-05
52 MEMBRANE PROTEIN COMPLEX 164 1020 1.325e-06 1.488e-05
53 CYTOPLASMIC VESICLE PART 106 601 1.732e-06 1.909e-05
54 PERINUCLEAR REGION OF CYTOPLASM 111 642 2.624e-06 2.836e-05
55 CORTICAL ACTIN CYTOSKELETON 20 58 2.671e-06 2.836e-05
56 EXTRACELLULAR SPACE 209 1376 2.927e-06 3.052e-05
57 SYNAPTIC MEMBRANE 55 261 3.213e-06 3.292e-05
58 EARLY ENDOSOME 61 301 3.677e-06 3.702e-05
59 VESICLE MEMBRANE 92 512 3.779e-06 3.74e-05
60 ACTIN FILAMENT 22 70 4.969e-06 4.837e-05
61 SITE OF POLARIZED GROWTH 36 149 6.842e-06 6.55e-05
62 BASEMENT MEMBRANE 26 93 8.028e-06 7.562e-05
63 ENDOCYTIC VESICLE MEMBRANE 36 152 1.103e-05 0.0001022
64 POSTSYNAPTIC MEMBRANE 44 205 1.846e-05 0.0001684
65 FILAMENTOUS ACTIN 10 20 2.063e-05 0.0001853
66 NEURON SPINE 30 121 2.278e-05 0.0002016
67 CYTOSKELETON 278 1967 2.371e-05 0.0002067
68 BASAL PLASMA MEMBRANE 13 33 2.97e-05 0.0002551
69 FILOPODIUM MEMBRANE 9 18 5.433e-05 0.0004598
70 CLATHRIN COATED VESICLE 35 157 5.633e-05 0.0004653
71 NEUROMUSCULAR JUNCTION 17 54 5.657e-05 0.0004653
72 CORTICAL CYTOSKELETON 22 81 6.315e-05 0.0005122
73 LEADING EDGE MEMBRANE 31 134 7.031e-05 0.0005625
74 LATERAL PLASMA MEMBRANE 16 50 7.452e-05 0.0005881
75 LAMELLIPODIUM 37 172 7.832e-05 0.0006098
76 CATION CHANNEL COMPLEX 36 167 9.286e-05 0.0007135
77 TRANS GOLGI NETWORK 40 193 9.794e-05 0.0007333
78 BASAL PART OF CELL 16 51 9.731e-05 0.0007333
79 CELL CORTEX PART 28 119 0.0001131 0.0008251
80 SARCOLEMMA 29 125 0.0001124 0.0008251
81 RUFFLE 34 156 0.0001144 0.0008251
82 COATED VESICLE 46 234 0.0001174 0.000836
83 POTASSIUM CHANNEL COMPLEX 23 90 0.0001207 0.0008494
84 MHC CLASS II PROTEIN COMPLEX 8 16 0.0001438 0.0009883
85 DENDRITE CYTOPLASM 8 16 0.0001438 0.0009883
86 TRANSPORTER COMPLEX 58 321 0.0001898 0.001289
87 EXOCYTIC VESICLE 31 142 0.0002173 0.001459
88 LYTIC VACUOLE MEMBRANE 51 275 0.0002362 0.001567
89 EARLY ENDOSOME MEMBRANE 26 113 0.0002855 0.001873
90 TRANSPORT VESICLE MEMBRANE 32 151 0.0003066 0.001989
91 FIBRIL 7 14 0.0003834 0.002434
92 AXOLEMMA 7 14 0.0003834 0.002434
93 TRANSPORT VESICLE 59 338 0.0004266 0.002679
94 ORGANELLE SUBCOMPARTMENT 55 311 0.0004739 0.002944
95 MICROTUBULE 68 405 0.0005062 0.003112
96 CLATHRIN COATED VESICLE MEMBRANE 20 81 0.0005303 0.003193
97 TRANS GOLGI NETWORK MEMBRANE 20 81 0.0005303 0.003193
98 SEMAPHORIN RECEPTOR COMPLEX 6 11 0.0005697 0.003395
99 CLATHRIN COATED ENDOCYTIC VESICLE MEMBRANE 14 48 0.0006039 0.003562
100 COLLAGEN TRIMER 21 88 0.0006346 0.003706
101 T TUBULE 13 45 0.001035 0.005978
102 EXOCYTIC VESICLE MEMBRANE 15 56 0.001044 0.005978
103 CELL PROJECTION CYTOPLASM 14 52 0.001438 0.008153
104 NEURON PROJECTION MEMBRANE 11 36 0.001501 0.008348
105 PRESYNAPSE 49 283 0.001491 0.008348
106 CELL PROJECTION MEMBRANE 51 298 0.001569 0.008644
107 IONOTROPIC GLUTAMATE RECEPTOR COMPLEX 13 47 0.001609 0.008701
108 MICROTUBULE PLUS END 7 17 0.0016 0.008701

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Cell_adhesion_molecules_.CAMs._hsa04514 50 145 1.182e-13 6.147e-12
2 Cytokine_cytokine_receptor_interaction_hsa04060 66 270 7.533e-10 1.959e-08
3 Hippo_signaling_pathway_hsa04390 43 154 1.074e-08 1.861e-07
4 TNF_signaling_pathway_hsa04668 32 108 1.784e-07 2.319e-06
5 Focal_adhesion_hsa04510 48 199 2.307e-07 2.399e-06
6 Phagosome_hsa04145 39 152 5.739e-07 4.974e-06
7 PI3K_Akt_signaling_pathway_hsa04151 68 352 5.939e-06 4.412e-05
8 Rap1_signaling_pathway_hsa04015 45 206 9.283e-06 6.034e-05
9 Jak_STAT_signaling_pathway_hsa04630 37 162 1.999e-05 0.0001155
10 MAPK_signaling_pathway_hsa04010 57 295 3.235e-05 0.0001682
11 ECM_receptor_interaction_hsa04512 22 82 7.721e-05 0.000365
12 Calcium_signaling_pathway_hsa04020 38 182 0.0001228 0.0005323
13 Regulation_of_actin_cytoskeleton_hsa04810 40 208 0.0005022 0.002009
14 Endocytosis_hsa04144 45 244 0.0006015 0.002134
15 HIF_1_signaling_pathway_hsa04066 23 100 0.0006272 0.002134
16 Apoptosis_hsa04210 29 138 0.0006616 0.002134
17 Ras_signaling_pathway_hsa04014 43 232 0.0007067 0.002134
18 NF_kappa_B_signaling_pathway_hsa04064 22 95 0.0007385 0.002134
19 Adherens_junction_hsa04520 18 72 0.0008438 0.002309
20 Tight_junction_hsa04530 33 170 0.001261 0.003278
21 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 28 139 0.0016 0.003963
22 p53_signaling_pathway_hsa04115 16 68 0.003128 0.007392
23 VEGF_signaling_pathway_hsa04370 14 59 0.005095 0.01152
24 ErbB_signaling_pathway_hsa04012 18 85 0.005951 0.01289
25 Autophagy_animal_hsa04140 24 128 0.008406 0.01748
26 Necroptosis_hsa04217 29 164 0.009347 0.01869
27 Ferroptosis_hsa04216 10 40 0.01152 0.02218
28 Phospholipase_D_signaling_pathway_hsa04072 26 146 0.0122 0.02266
29 cAMP_signaling_pathway_hsa04024 32 198 0.02309 0.0414
30 TGF_beta_signaling_pathway_hsa04350 16 84 0.02433 0.04218
31 Apoptosis_multiple_species_hsa04215 8 33 0.02718 0.04559
32 AMPK_signaling_pathway_hsa04152 21 121 0.02927 0.04756
33 mTOR_signaling_pathway_hsa04150 25 151 0.03163 0.04983
34 Hippo_signaling_pathway_multiple_species_hsa04392 7 29 0.03855 0.05896
35 Sphingolipid_signaling_pathway_hsa04071 20 118 0.04086 0.0607
36 Phosphatidylinositol_signaling_system_hsa04070 17 99 0.05054 0.07301
37 Cellular_senescence_hsa04218 25 160 0.05726 0.08047
38 Wnt_signaling_pathway_hsa04310 23 146 0.06126 0.08383
39 FoxO_signaling_pathway_hsa04068 21 132 0.06543 0.08692
40 Gap_junction_hsa04540 15 88 0.06687 0.08692
41 cGMP_PKG_signaling_pathway_hsa04022 24 163 0.1042 0.1322
42 ABC_transporters_hsa02010 8 45 0.1282 0.1588
43 Lysosome_hsa04142 18 123 0.1496 0.181
44 Neuroactive_ligand_receptor_interaction_hsa04080 36 278 0.2111 0.2495
45 Apelin_signaling_pathway_hsa04371 18 137 0.2809 0.3246
46 Hedgehog_signaling_pathway_hsa04340 6 47 0.4394 0.4968
47 Notch_signaling_pathway_hsa04330 6 48 0.4602 0.5092
48 Cell_cycle_hsa04110 14 124 0.5401 0.5851
49 Mitophagy_animal_hsa04137 7 65 0.6097 0.647
50 Autophagy_other_hsa04136 3 32 0.7158 0.7444
51 Oocyte_meiosis_hsa04114 11 124 0.8396 0.8404
52 Peroxisome_hsa04146 7 83 0.8404 0.8404

Quest ID: a4e62834b7d6aa1058143a313a8bd730