Visible node/edge number:
Node colors:
Node labels:

show label of nodes with degree >=

Node sizes:
Edge colors:
Edge widths factor:
Layout:

gravity >=

edgeLength =

GRN in network:

Notice: IE browser need to manually refresh (F5) this page after resetting the network.

This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-362-3p ABCA1 0.11 0.64379 -0.05 0.8308 miRanda -0.27 0 NA
2 hsa-miR-362-3p ABCA6 0.11 0.64379 -0.41 0.30457 miRanda -0.49 1.0E-5 NA
3 hsa-miR-362-3p ABCC9 0.11 0.64379 -0.58 0.0487 miRanda -0.5 0 NA
4 hsa-miR-362-3p ABCD2 0.11 0.64379 -0.21 0.52359 miRanda -0.3 0.00143 NA
5 hsa-miR-362-3p ACAN 0.11 0.64379 -0.41 0.10954 miRanda -0.17 0.02006 NA
6 hsa-miR-362-3p ACER2 0.11 0.64379 -0.48 0.01435 miRanda -0.19 0.00079 NA
7 hsa-miR-362-3p ADAM28 0.11 0.64379 -0.48 0.15863 PITA -0.24 0.01584 NA
8 hsa-miR-362-3p ADAM33 0.11 0.64379 -0.33 0.4232 miRanda -0.41 0.0005 NA
9 hsa-miR-362-3p ADAMTS1 0.11 0.64379 -0.39 0.09809 miRanda -0.3 0 NA
10 hsa-miR-362-5p ADAMTS12 0.51 0.05114 -0.4 0.28425 mirMAP -0.68 0 NA
11 hsa-miR-362-3p ADAMTS4 0.11 0.64379 -0.28 0.27653 miRanda -0.23 0.00078 NA
12 hsa-miR-362-3p ADAMTSL1 0.11 0.64379 -0.13 0.64223 miRanda -0.33 7.0E-5 NA
13 hsa-miR-362-3p ADAMTSL4 0.11 0.64379 -0.41 0.09478 miRNATAP -0.24 0.00059 NA
14 hsa-miR-21-3p ADCY1 0.06 0.84434 -0.69 0.01679 mirMAP -0.32 0.00949 NA
15 hsa-miR-362-3p ADCY1 0.11 0.64379 -0.69 0.01679 miRanda -0.32 0.00014 NA
16 hsa-miR-362-3p ADCYAP1 0.11 0.64379 -0.2 0.67185 miRanda -0.63 0 NA
17 hsa-miR-362-5p ADCYAP1 0.51 0.05114 -0.2 0.67185 PITA; miRNATAP -0.81 0 NA
18 hsa-miR-362-3p ADD2 0.11 0.64379 -0.98 0.01735 PITA; miRanda -0.55 0 NA
19 hsa-miR-362-5p ADHFE1 0.51 0.05114 0.01 0.98351 TargetScan; miRNATAP -0.23 0.00496 NA
20 hsa-miR-21-3p ADIPOQ 0.06 0.84434 -0.49 0.50915 MirTarget -1.45 0 NA
21 hsa-miR-362-5p AFAP1 0.51 0.05114 -0.16 0.3649 mirMAP -0.11 0.00028 NA
22 hsa-miR-362-3p AFF4 0.11 0.64379 -0.05 0.75124 PITA -0.12 0 NA
23 hsa-miR-362-3p AGAP11 0.11 0.64379 -0.07 0.78145 miRanda -0.18 0.01802 NA
24 hsa-miR-362-3p AGPAT4 0.11 0.64379 -0.78 0.00264 MirTarget -0.32 1.0E-5 NA
25 hsa-miR-362-5p AGPAT4 0.51 0.05114 -0.78 0.00264 mirMAP -0.52 0 NA
26 hsa-miR-362-3p AHNAK 0.11 0.64379 -0.62 0.01795 PITA; miRanda; miRNATAP -0.22 3.0E-5 NA
27 hsa-miR-362-3p AK5 0.11 0.64379 -0.8 0.01153 miRanda -0.35 0.00012 NA
28 hsa-miR-21-3p AKAP11 0.06 0.84434 0.24 0.18121 MirTarget -0.14 0.00369 NA
29 hsa-miR-362-3p AKAP2 0.11 0.64379 0.17 0.40729 PITA; miRNATAP -0.25 1.0E-5 NA
30 hsa-miR-362-3p AKT3 0.11 0.64379 -0.59 0.01641 miRanda -0.42 0 NA
31 hsa-miR-362-5p AKT3 0.51 0.05114 -0.59 0.01641 PITA; TargetScan; miRNATAP -0.52 0 NA
32 hsa-miR-362-3p ALCAM 0.11 0.64379 -0.18 0.41514 miRanda -0.1 0.04247 NA
33 hsa-miR-362-3p ALDH1A2 0.11 0.64379 -1.71 0.00293 miRanda -0.4 0.02021 NA
34 hsa-miR-362-5p ALPK3 0.51 0.05114 0.32 0.37339 mirMAP -0.2 0.04828 NA
35 hsa-miR-21-3p AMIGO2 0.06 0.84434 -0.38 0.13272 MirTarget -0.46 1.0E-5 NA
36 hsa-miR-362-3p AMOTL1 0.11 0.64379 -0.76 0.00615 MirTarget -0.45 0 NA
37 hsa-miR-362-3p ANGPTL2 0.11 0.64379 -0.63 0.02845 miRanda; miRNATAP -0.44 0 NA
38 hsa-miR-362-5p ANGPTL7 0.51 0.05114 -0.6 0.16236 miRNATAP -0.81 0 NA
39 hsa-miR-362-3p ANKRD44 0.11 0.64379 -0.5 0.04561 miRanda -0.23 0.00135 NA
40 hsa-miR-362-3p ANKRD6 0.11 0.64379 -0.33 0.13971 miRanda -0.2 0.00215 NA
41 hsa-miR-362-3p ANO1 0.11 0.64379 -1.17 0.00028 miRanda -0.27 0.00287 NA
42 hsa-miR-362-3p AP4S1 0.11 0.64379 -0.09 0.55098 miRanda -0.12 0.00739 NA
43 hsa-miR-362-3p APBA2 0.11 0.64379 -0.62 0.01322 miRanda; miRNATAP -0.28 9.0E-5 NA
44 hsa-miR-362-3p APBB1IP 0.11 0.64379 -0.53 0.06348 miRanda -0.33 8.0E-5 NA
45 hsa-miR-362-3p APOOL 0.11 0.64379 0.18 0.28233 miRanda -0.13 0.00821 NA
46 hsa-miR-362-3p AR 0.11 0.64379 -0.72 0.08465 miRanda -0.59 0 NA
47 hsa-miR-21-3p ARHGAP6 0.06 0.84434 -0.1 0.77625 MirTarget -0.59 5.0E-5 NA
48 hsa-miR-362-3p ARHGEF15 0.11 0.64379 -0.54 0.00479 miRanda -0.22 5.0E-5 NA
49 hsa-miR-362-3p ARHGEF6 0.11 0.64379 -0.48 0.03477 MirTarget; miRanda -0.32 0 NA
50 hsa-miR-21-3p ARL10 0.06 0.84434 -0.13 0.63188 mirMAP -0.45 4.0E-5 NA
51 hsa-miR-362-3p ARL10 0.11 0.64379 -0.13 0.63188 mirMAP -0.33 1.0E-5 NA
52 hsa-miR-21-3p ARL2BP 0.06 0.84434 0.1 0.503 MirTarget -0.11 0.0001 NA
53 hsa-miR-362-3p ARL4C 0.11 0.64379 -0.39 0.13323 PITA -0.32 0 NA
54 hsa-miR-362-3p ARL4D 0.11 0.64379 0.07 0.75696 miRNATAP -0.18 0.00433 NA
55 hsa-miR-362-3p ARMC9 0.11 0.64379 -0.32 0.03253 miRanda -0.12 0.00121 NA
56 hsa-miR-362-3p ARNT2 0.11 0.64379 -0.83 0.01329 miRanda -0.36 0.0002 NA
57 hsa-miR-362-3p ASAP1 0.11 0.64379 0.16 0.3669 miRanda -0.11 0.00754 NA
58 hsa-miR-362-3p ASXL2 0.11 0.64379 -0.01 0.96811 miRanda -0.16 3.0E-5 NA
59 hsa-miR-362-5p ASXL2 0.51 0.05114 -0.01 0.96811 mirMAP -0.12 0.00097 NA
60 hsa-miR-362-3p ATP10A 0.11 0.64379 -0.48 0.07791 miRanda -0.39 0 NA
61 hsa-miR-21-3p ATP2B4 0.06 0.84434 -0.34 0.13246 mirMAP -0.5 0 NA
62 hsa-miR-362-5p ATP2B4 0.51 0.05114 -0.34 0.13246 miRNATAP -0.41 0 NA
63 hsa-miR-21-3p ATRNL1 0.06 0.84434 -0.66 0.11603 MirTarget -1.42 0 NA
64 hsa-miR-362-3p ATXN1 0.11 0.64379 -0.19 0.22524 MirTarget; PITA; miRanda; miRNATAP -0.15 0 NA
65 hsa-miR-362-5p ATXN1 0.51 0.05114 -0.19 0.22524 mirMAP -0.18 0 NA
66 hsa-miR-362-3p B3GALT1 0.11 0.64379 -0.92 0.05694 miRanda -0.34 0.01452 NA
67 hsa-miR-362-3p B3GNT9 0.11 0.64379 -0.42 0.00761 miRanda -0.11 0.00601 NA
68 hsa-miR-362-3p BAALC 0.11 0.64379 -0.56 0.07918 miRanda -0.44 0 NA
69 hsa-miR-21-3p BACE1 0.06 0.84434 -0 0.98214 mirMAP -0.29 0 NA
70 hsa-miR-362-3p BAHCC1 0.11 0.64379 -0.14 0.5649 PITA; miRanda -0.24 0.00056 NA
71 hsa-miR-362-3p BCL6 0.11 0.64379 -0.43 0.02067 miRanda -0.15 0.00147 NA
72 hsa-miR-362-3p BEND4 0.11 0.64379 -0.57 0.13158 miRanda -0.35 0.00126 NA
73 hsa-miR-362-3p BEX4 0.11 0.64379 -0.56 0.02756 miRanda -0.3 4.0E-5 NA
74 hsa-miR-362-3p BHLHE22 0.11 0.64379 -0.08 0.78042 miRanda -0.3 0.00045 NA
75 hsa-miR-362-3p BMF 0.11 0.64379 0.05 0.80648 PITA; miRanda; miRNATAP -0.11 0.03223 NA
76 hsa-miR-362-5p BMP1 0.51 0.05114 -0.2 0.27787 mirMAP -0.25 0 NA
77 hsa-miR-362-3p BMP6 0.11 0.64379 -0.95 0 miRanda -0.21 0.00048 NA
78 hsa-miR-362-3p BMPR1B 0.11 0.64379 -1.56 0.00021 MirTarget; miRanda -0.58 0 NA
79 hsa-miR-362-3p BMPR2 0.11 0.64379 -0.08 0.64874 MirTarget; PITA; miRanda; miRNATAP -0.15 1.0E-5 NA
80 hsa-miR-362-5p BNC2 0.51 0.05114 -0.53 0.08426 PITA -0.64 0 NA
81 hsa-miR-362-3p BTK 0.11 0.64379 -0.56 0.06441 miRanda -0.37 3.0E-5 NA
82 hsa-miR-362-3p CACNA1B 0.11 0.64379 -1.82 0.00013 MirTarget; miRNATAP -0.39 0.00442 NA
83 hsa-miR-362-5p CACNA1E 0.51 0.05114 -0.97 0.01412 mirMAP -0.52 0 NA
84 hsa-miR-21-3p CACNA2D1 0.06 0.84434 -0.85 0.05575 mirMAP -1.03 0 NA
85 hsa-miR-362-3p CACNA2D1 0.11 0.64379 -0.85 0.05575 miRanda -0.78 0 NA
86 hsa-miR-362-3p CADM1 0.11 0.64379 -0.57 0.06122 PITA; miRanda; miRNATAP -0.41 0 NA
87 hsa-miR-362-3p CADM3 0.11 0.64379 -0.5 0.33965 miRanda -0.76 0 NA
88 hsa-miR-362-3p CALCRL 0.11 0.64379 -0.45 0.04092 miRanda -0.33 0 NA
89 hsa-miR-362-3p CAMK2B 0.11 0.64379 -0.01 0.97166 miRanda -0.39 0.00026 NA
90 hsa-miR-362-5p CAMK2B 0.51 0.05114 -0.01 0.97166 miRNATAP -0.43 3.0E-5 NA
91 hsa-miR-362-3p CAMK4 0.11 0.64379 -0.8 0.0051 miRanda -0.25 0.00198 NA
92 hsa-miR-21-3p CAMLG 0.06 0.84434 0.15 0.34489 MirTarget -0.1 0.00733 NA
93 hsa-miR-362-3p CAPN14 0.11 0.64379 -0.42 0.33347 miRanda -0.27 0.02922 NA
94 hsa-miR-362-3p CASS4 0.11 0.64379 -0.55 0.04983 miRanda -0.32 7.0E-5 NA
95 hsa-miR-362-5p CBFA2T3 0.51 0.05114 -2.08 0 PITA -0.43 0.00017 NA
96 hsa-miR-362-3p CBLN2 0.11 0.64379 0.33 0.35314 miRanda -0.2 0.04895 NA
97 hsa-miR-362-3p CBX6 0.11 0.64379 -0.16 0.54398 mirMAP -0.3 0.00011 NA
98 hsa-miR-362-5p CBX6 0.51 0.05114 -0.16 0.54398 mirMAP -0.42 0 NA
99 hsa-miR-362-3p CC2D2A 0.11 0.64379 0.14 0.60106 miRanda -0.25 0.00089 NA
100 hsa-miR-362-3p CCDC102B 0.11 0.64379 -0.36 0.06947 miRanda -0.18 0.00154 NA
101 hsa-miR-362-3p CCDC85A 0.11 0.64379 -0.26 0.35716 miRanda; miRNATAP -0.37 1.0E-5 NA
102 hsa-miR-362-3p CCDC89 0.11 0.64379 -0.04 0.849 miRanda -0.16 0.01666 NA
103 hsa-miR-362-3p CCL19 0.11 0.64379 -0.2 0.71713 miRanda -0.49 0.00241 NA
104 hsa-miR-362-3p CCNJL 0.11 0.64379 -0.46 0.06809 miRanda -0.22 0.00205 NA
105 hsa-miR-362-3p CCPG1 0.11 0.64379 -0.39 0.02629 miRanda -0.12 0.00048 NA
106 hsa-miR-362-3p CD36 0.11 0.64379 -0.56 0.10855 miRanda -0.36 0.00049 NA
107 hsa-miR-362-3p CD79B 0.11 0.64379 -0.28 0.39374 PITA; miRanda -0.22 0.02274 NA
108 hsa-miR-362-3p CDH11 0.11 0.64379 -0.86 0.00288 miRanda -0.43 0 NA
109 hsa-miR-362-3p CDH13 0.11 0.64379 -0.45 0.02591 MirTarget; miRanda -0.19 0.0004 NA
110 hsa-miR-21-3p CDK14 0.06 0.84434 -0.65 0.01679 MirTarget -0.51 1.0E-5 NA
111 hsa-miR-362-3p CDYL2 0.11 0.64379 -0.42 0.08783 miRanda -0.28 8.0E-5 NA
112 hsa-miR-362-5p CEP97 0.51 0.05114 -0.26 0.02644 MirTarget -0.13 2.0E-5 NA
113 hsa-miR-362-3p CFH 0.11 0.64379 -0.52 0.05574 miRanda -0.42 0 NA
114 hsa-miR-21-3p CHL1 0.06 0.84434 -0.75 0.06297 MirTarget -0.99 0 NA
115 hsa-miR-362-3p CHL1 0.11 0.64379 -0.75 0.06297 miRanda -0.61 0 NA
116 hsa-miR-362-5p CHODL 0.51 0.05114 -0.13 0.75219 PITA -0.39 0.00037 NA
117 hsa-miR-362-3p CHRDL1 0.11 0.64379 -0.12 0.84302 PITA; miRanda; miRNATAP -0.88 0 NA
118 hsa-miR-362-5p CHSY1 0.51 0.05114 -0.22 0.16771 MirTarget; PITA; TargetScan; miRNATAP -0.19 0 NA
119 hsa-miR-362-5p CIITA 0.51 0.05114 -0.35 0.34967 mirMAP -0.47 0 NA
120 hsa-miR-362-3p CLCF1 0.11 0.64379 -0.01 0.94286 miRanda -0.14 0.00726 NA
121 hsa-miR-362-5p CLIC4 0.51 0.05114 -0.29 0.16683 PITA -0.27 0 NA
122 hsa-miR-362-3p CLIP4 0.11 0.64379 -0.43 0.14009 miRanda -0.48 0 NA
123 hsa-miR-362-3p CLU 0.11 0.64379 0.02 0.95834 miRanda -0.22 0.019 NA
124 hsa-miR-362-3p CMTM3 0.11 0.64379 -0.4 0.05724 miRanda -0.29 0 NA
125 hsa-miR-362-3p CNNM1 0.11 0.64379 0.03 0.92696 miRanda -0.38 0.00015 NA
126 hsa-miR-362-3p CNPY4 0.11 0.64379 -0.17 0.22383 miRanda -0.12 0.00044 NA
127 hsa-miR-362-3p CNR1 0.11 0.64379 -0.02 0.96823 miRanda -0.66 0 NA
128 hsa-miR-21-3p CNRIP1 0.06 0.84434 -0.49 0.01296 MirTarget -0.44 0 NA
129 hsa-miR-21-3p COBLL1 0.06 0.84434 0.51 0.00495 mirMAP -0.19 0.00182 NA
130 hsa-miR-362-3p COL11A1 0.11 0.64379 -1.04 0.02407 miRanda -0.63 0 NA
131 hsa-miR-362-3p COL13A1 0.11 0.64379 -0.36 0.15915 miRanda -0.15 0.04683 NA
132 hsa-miR-362-3p COL24A1 0.11 0.64379 -1.04 0.00275 miRanda -0.53 0 NA
133 hsa-miR-362-3p COL4A1 0.11 0.64379 -0.46 0.06991 miRanda -0.23 1.0E-5 NA
134 hsa-miR-362-3p COL5A3 0.11 0.64379 -0.29 0.25685 miRanda -0.19 0.00776 NA
135 hsa-miR-362-3p COL6A3 0.11 0.64379 -0.68 0.04435 miRanda -0.42 0 NA
136 hsa-miR-362-3p CORIN 0.11 0.64379 -0.51 0.16112 miRanda -0.43 5.0E-5 NA
137 hsa-miR-362-5p CORO2B 0.51 0.05114 -0.38 0.20458 PITA; TargetScan; miRNATAP -0.52 0 NA
138 hsa-miR-21-3p CPEB4 0.06 0.84434 -0.14 0.38436 mirMAP -0.11 0.04416 NA
139 hsa-miR-362-3p CPEB4 0.11 0.64379 -0.14 0.38436 PITA; miRanda; miRNATAP -0.17 0 NA
140 hsa-miR-362-5p CPEB4 0.51 0.05114 -0.14 0.38436 PITA; TargetScan; miRNATAP -0.13 0.00015 NA
141 hsa-miR-21-3p CPLX2 0.06 0.84434 1.42 0.00389 mirMAP -0.69 0.00113 NA
142 hsa-miR-362-3p CR2 0.11 0.64379 -0.52 0.38404 miRanda -0.4 0.02325 NA
143 hsa-miR-362-3p CREB5 0.11 0.64379 0.1 0.71971 PITA -0.25 0.00256 NA
144 hsa-miR-362-5p CREB5 0.51 0.05114 0.1 0.71971 PITA -0.21 0.00718 NA
145 hsa-miR-21-3p CREBL2 0.06 0.84434 -0.17 0.22354 MirTarget -0.12 0.00059 NA
146 hsa-miR-362-3p CRIP2 0.11 0.64379 -0.59 0.00305 miRanda -0.22 1.0E-5 NA
147 hsa-miR-362-3p CRK 0.11 0.64379 -0.35 0.02694 miRanda -0.12 0.00011 NA
148 hsa-miR-362-3p CRMP1 0.11 0.64379 -0.15 0.5174 MirTarget; PITA; miRanda; miRNATAP -0.33 0 NA
149 hsa-miR-362-3p CSGALNACT1 0.11 0.64379 -0.38 0.07842 miRanda -0.2 0.00133 NA
150 hsa-miR-362-5p CSMD2 0.51 0.05114 -0.86 0.00692 miRNATAP -0.58 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 135 1672 4.536e-21 2.11e-17
2 NEUROGENESIS 119 1402 3.002e-20 6.985e-17
3 CELL DEVELOPMENT 117 1426 9.556e-19 1.482e-15
4 CARDIOVASCULAR SYSTEM DEVELOPMENT 80 788 4.041e-18 3.761e-15
5 CIRCULATORY SYSTEM DEVELOPMENT 80 788 4.041e-18 3.761e-15
6 REGULATION OF CELL DIFFERENTIATION 117 1492 3.049e-17 2.365e-14
7 VASCULATURE DEVELOPMENT 55 469 2.265e-15 1.505e-12
8 BLOOD VESSEL MORPHOGENESIS 47 364 7.059e-15 4.106e-12
9 REGULATION OF CELL DEVELOPMENT 75 836 3.731e-14 1.929e-11
10 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 70 750 4.151e-14 1.931e-11
11 RESPONSE TO ENDOGENOUS STIMULUS 106 1450 1.272e-13 4.934e-11
12 ANGIOGENESIS 40 293 1.207e-13 4.934e-11
13 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 83 1021 3.36e-13 1.196e-10
14 NEURON DIFFERENTIATION 75 874 3.598e-13 1.196e-10
15 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 101 1395 9.539e-13 2.959e-10
16 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 88 1142 1.2e-12 3.489e-10
17 REGULATION OF NEURON DIFFERENTIATION 55 554 2.308e-12 5.965e-10
18 TISSUE DEVELOPMENT 106 1518 2.279e-12 5.965e-10
19 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 121 1848 3.827e-12 9.372e-10
20 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 52 513 4.286e-12 9.497e-10
21 CELLULAR COMPONENT MORPHOGENESIS 74 900 4.235e-12 9.497e-10
22 POSITIVE REGULATION OF CELL DIFFERENTIATION 68 823 2.718e-11 5.749e-09
23 REGULATION OF CELLULAR COMPONENT MOVEMENT 65 771 3.262e-11 6.6e-09
24 NEURON DEVELOPMENT 60 687 4.773e-11 9.253e-09
25 NEURON PROJECTION MORPHOGENESIS 43 402 5.867e-11 1.092e-08
26 BIOLOGICAL ADHESION 78 1032 6.707e-11 1.2e-08
27 SKELETAL SYSTEM DEVELOPMENT 46 455 8.434e-11 1.445e-08
28 CELL PROJECTION ORGANIZATION 71 902 8.695e-11 1.445e-08
29 RESPONSE TO ORGANIC CYCLIC COMPOUND 71 917 1.81e-10 2.764e-08
30 LOCOMOTION 81 1114 1.841e-10 2.764e-08
31 BEHAVIOR 49 516 1.818e-10 2.764e-08
32 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 73 957 1.924e-10 2.797e-08
33 RESPONSE TO LIPID 69 888 2.865e-10 4.039e-08
34 NEURON PROJECTION DEVELOPMENT 50 545 3.93e-10 5.378e-08
35 REGULATION OF CELL MORPHOGENESIS 50 552 6.103e-10 8.114e-08
36 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 73 983 6.338e-10 8.192e-08
37 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 111 1784 7.393e-10 9.297e-08
38 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 74 1008 7.977e-10 9.768e-08
39 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 87 1275 8.854e-10 1.056e-07
40 RESPONSE TO ALCOHOL 38 362 1.333e-09 1.55e-07
41 RESPONSE TO OXYGEN CONTAINING COMPOUND 91 1381 2.009e-09 2.239e-07
42 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 90 1360 2.021e-09 2.239e-07
43 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 38 368 2.116e-09 2.29e-07
44 REGULATION OF SYSTEM PROCESS 46 507 2.876e-09 3.042e-07
45 REGULATION OF NEURON PROJECTION DEVELOPMENT 40 408 3.591e-09 3.713e-07
46 PROTEIN PHOSPHORYLATION 69 944 3.74e-09 3.783e-07
47 TAXIS 43 464 5.092e-09 5.041e-07
48 CELL PART MORPHOGENESIS 52 633 8.081e-09 7.78e-07
49 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 41 437 8.193e-09 7.78e-07
50 POSITIVE REGULATION OF GENE EXPRESSION 105 1733 9.644e-09 8.975e-07
51 REGULATION OF HOMEOSTATIC PROCESS 41 447 1.562e-08 1.425e-06
52 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 70 1004 1.958e-08 1.752e-06
53 REGULATION OF CELL PROLIFERATION 93 1496 2.3e-08 2.02e-06
54 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 34 337 2.676e-08 2.306e-06
55 CENTRAL NERVOUS SYSTEM DEVELOPMENT 63 872 2.882e-08 2.438e-06
56 RESPONSE TO EXTERNAL STIMULUS 107 1821 3.429e-08 2.849e-06
57 RESPONSE TO STEROID HORMONE 43 497 3.811e-08 3.111e-06
58 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 106 1805 4.141e-08 3.263e-06
59 ORGAN MORPHOGENESIS 61 841 4.207e-08 3.263e-06
60 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 17 98 4.1e-08 3.263e-06
61 REGULATION OF CELL DEATH 91 1472 4.313e-08 3.29e-06
62 HEART DEVELOPMENT 41 466 5.007e-08 3.758e-06
63 UROGENITAL SYSTEM DEVELOPMENT 31 299 5.922e-08 4.374e-06
64 INTRACELLULAR SIGNAL TRANSDUCTION 95 1572 6.181e-08 4.494e-06
65 SINGLE ORGANISM BEHAVIOR 36 384 6.868e-08 4.868e-06
66 REGULATION OF EPITHELIAL CELL PROLIFERATION 30 285 6.905e-08 4.868e-06
67 REGULATION OF TRANSPORT 105 1804 7.615e-08 5.288e-06
68 REGULATION OF ION TRANSPORT 47 592 1.201e-07 8.221e-06
69 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 40 465 1.336e-07 9.007e-06
70 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 69 1036 1.452e-07 9.381e-06
71 REGULATION OF CELL PROJECTION ORGANIZATION 45 558 1.436e-07 9.381e-06
72 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 69 1036 1.452e-07 9.381e-06
73 REGULATION OF BLOOD CIRCULATION 30 295 1.482e-07 9.444e-06
74 NEGATIVE REGULATION OF CELL COMMUNICATION 76 1192 1.889e-07 1.188e-05
75 POSITIVE REGULATION OF CELL DEVELOPMENT 40 472 1.983e-07 1.23e-05
76 REGULATION OF HEART CONTRACTION 25 221 2.168e-07 1.328e-05
77 RESPONSE TO ACID CHEMICAL 31 319 2.545e-07 1.538e-05
78 POSITIVE REGULATION OF CELL COMMUNICATION 91 1532 2.637e-07 1.573e-05
79 CONNECTIVE TISSUE DEVELOPMENT 23 194 2.843e-07 1.674e-05
80 HEAD DEVELOPMENT 52 709 3.112e-07 1.81e-05
81 POSITIVE REGULATION OF RESPONSE TO STIMULUS 108 1929 3.385e-07 1.944e-05
82 RESPONSE TO HORMONE 61 893 3.426e-07 1.944e-05
83 POSITIVE REGULATION OF CELL PROLIFERATION 57 814 3.816e-07 2.139e-05
84 CELL MOTILITY 58 835 3.918e-07 2.145e-05
85 LOCALIZATION OF CELL 58 835 3.918e-07 2.145e-05
86 MULTI MULTICELLULAR ORGANISM PROCESS 24 213 4.067e-07 2.2e-05
87 BONE DEVELOPMENT 20 156 4.8e-07 2.567e-05
88 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 25 232 5.471e-07 2.893e-05
89 CELL CELL ADHESION 46 608 6.458e-07 3.376e-05
90 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 95 1656 6.696e-07 3.462e-05
91 OSSIFICATION 26 251 7.005e-07 3.543e-05
92 REGULATION OF CELL ADHESION 47 629 6.932e-07 3.543e-05
93 NEURON PROJECTION GUIDANCE 23 205 7.624e-07 3.814e-05
94 CARTILAGE DEVELOPMENT 19 147 8.148e-07 4.033e-05
95 EXTRACELLULAR STRUCTURE ORGANIZATION 29 304 9.061e-07 4.438e-05
96 REGULATION OF MAPK CASCADE 48 660 1.139e-06 5.521e-05
97 HOMOPHILIC CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 19 153 1.508e-06 7.162e-05
98 REGULATION OF PHOSPHORUS METABOLIC PROCESS 92 1618 1.502e-06 7.162e-05
99 CELLULAR RESPONSE TO LIPID 37 457 1.704e-06 7.928e-05
100 POSITIVE REGULATION OF LOCOMOTION 35 420 1.693e-06 7.928e-05
101 TISSUE MORPHOGENESIS 41 533 1.743e-06 8.032e-05
102 SYNAPTIC SIGNALING 35 424 2.099e-06 9.575e-05
103 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 54 801 2.463e-06 0.0001113
104 REGULATION OF DENDRITIC SPINE DEVELOPMENT 11 56 2.87e-06 0.0001284
105 NEGATIVE REGULATION OF CELL PROLIFERATION 46 643 2.974e-06 0.0001318
106 POSITIVE REGULATION OF NEURON DIFFERENTIATION 28 306 3.15e-06 0.0001381
107 MUSCLE STRUCTURE DEVELOPMENT 35 432 3.195e-06 0.0001381
108 POSITIVE REGULATION OF CELL DEATH 44 605 3.205e-06 0.0001381
109 CELL CELL SIGNALING 52 767 3.234e-06 0.0001381
110 POSITIVE REGULATION OF MAPK CASCADE 37 470 3.281e-06 0.0001388
111 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 12 68 3.349e-06 0.0001404
112 REGULATION OF METAL ION TRANSPORT 29 325 3.474e-06 0.0001443
113 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 26 274 3.636e-06 0.0001497
114 REGULATION OF CALCIUM ION TRANSPORT 22 209 3.822e-06 0.000156
115 SENSORY ORGAN DEVELOPMENT 38 493 3.979e-06 0.0001596
116 REGULATION OF DENDRITE DEVELOPMENT 16 120 3.952e-06 0.0001596
117 TUBE DEVELOPMENT 41 552 4.163e-06 0.0001655
118 REGULATION OF SEQUESTERING OF CALCIUM ION 15 107 4.201e-06 0.0001657
119 CIRCULATORY SYSTEM PROCESS 31 366 4.742e-06 0.0001854
120 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 53 799 4.885e-06 0.0001894
121 LOCOMOTORY BEHAVIOR 20 181 5.013e-06 0.0001928
122 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 33 404 5.121e-06 0.0001953
123 NEGATIVE REGULATION OF LOCOMOTION 25 263 5.402e-06 0.0002044
124 DEVELOPMENTAL GROWTH 29 333 5.593e-06 0.0002099
125 MATERNAL PROCESS INVOLVED IN FEMALE PREGNANCY 11 60 5.824e-06 0.0002168
126 REGULATION OF TRANSMEMBRANE TRANSPORT 34 426 6.096e-06 0.0002251
127 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 18 154 6.734e-06 0.0002467
128 CELL JUNCTION ORGANIZATION 20 185 6.989e-06 0.0002521
129 GROWTH 33 410 6.987e-06 0.0002521
130 SKELETAL SYSTEM MORPHOGENESIS 21 201 7.099e-06 0.0002541
131 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 68 1135 7.393e-06 0.0002626
132 NEGATIVE REGULATION OF CELL DEVELOPMENT 27 303 7.689e-06 0.0002711
133 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 56 876 7.848e-06 0.0002745
134 REGULATION OF SYNAPSE ORGANIZATION 15 113 8.323e-06 0.0002848
135 REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION 21 203 8.283e-06 0.0002848
136 PHOSPHORYLATION 72 1228 8.256e-06 0.0002848
137 NEGATIVE REGULATION OF CELL DIFFERENTIATION 43 609 8.675e-06 0.0002946
138 TUBE MORPHOGENESIS 28 323 8.813e-06 0.0002971
139 EPITHELIUM DEVELOPMENT 59 945 9.119e-06 0.0003053
140 SENSORY PERCEPTION OF PAIN 12 75 9.628e-06 0.00032
141 RETINA VASCULATURE DEVELOPMENT IN CAMERA TYPE EYE 6 16 1.007e-05 0.0003324
142 RESPONSE TO GROWTH FACTOR 36 475 1.033e-05 0.0003386
143 EYE DEVELOPMENT 28 326 1.047e-05 0.0003407
144 CALCIUM ION TRANSMEMBRANE IMPORT INTO CYTOSOL 9 42 1.093e-05 0.0003507
145 CALCIUM ION IMPORT INTO CYTOSOL 9 42 1.093e-05 0.0003507
146 CYTOSOLIC CALCIUM ION TRANSPORT 10 53 1.184e-05 0.0003774
147 RESPONSE TO OXYGEN LEVELS 27 311 1.236e-05 0.0003913
148 ENDOTHELIUM DEVELOPMENT 13 90 1.308e-05 0.0004113
149 MUSCLE ORGAN DEVELOPMENT 25 277 1.332e-05 0.0004161
150 CELL FATE COMMITMENT 22 227 1.442e-05 0.0004474
151 REGULATION OF CARDIAC CONDUCTION 11 66 1.512e-05 0.0004658
152 RESPONSE TO FLUID SHEAR STRESS 8 34 1.629e-05 0.0004988
153 REGULATION OF CHEMOTAXIS 19 180 1.658e-05 0.0005044
154 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 11 67 1.753e-05 0.0005296
155 RESPONSE TO NITROGEN COMPOUND 54 859 1.827e-05 0.0005449
156 ADULT BEHAVIOR 16 135 1.815e-05 0.0005449
157 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 57 926 1.953e-05 0.0005787
158 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 82 1492 2.063e-05 0.0006076
159 REGULATION OF AXONOGENESIS 18 168 2.246e-05 0.0006574
160 REGULATION OF ION HOMEOSTASIS 20 201 2.391e-05 0.0006952
161 REGULATION OF BLOOD PRESSURE 18 169 2.435e-05 0.0007036
162 REGULATION OF MEMBRANE POTENTIAL 28 343 2.656e-05 0.000758
163 DIVALENT INORGANIC CATION HOMEOSTASIS 28 343 2.656e-05 0.000758
164 REGULATION OF DEVELOPMENTAL GROWTH 25 289 2.732e-05 0.0007752
165 PROTEOGLYCAN METABOLIC PROCESS 12 83 2.773e-05 0.0007819
166 CELL CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 20 204 2.962e-05 0.0008302
167 POSITIVE REGULATION OF OSSIFICATION 12 84 3.135e-05 0.0008734
168 POSITIVE REGULATION OF KINASE ACTIVITY 35 482 3.35e-05 0.0009278
169 RESPONSE TO WOUNDING 39 563 3.464e-05 0.0009537
170 ENDOTHELIAL CELL DIFFERENTIATION 11 72 3.524e-05 0.0009644
171 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 19 191 3.808e-05 0.001036
172 SECRETION BY CELL 35 486 3.968e-05 0.001073
173 SECRETION 40 588 4.13e-05 0.001111
174 RESPONSE TO CORTICOSTEROID 18 176 4.195e-05 0.001122
175 RESPONSE TO CALCIUM ION 14 115 4.437e-05 0.00118
176 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 23 262 4.51e-05 0.001192
177 ACTIN FILAMENT BASED PROCESS 33 450 4.61e-05 0.001205
178 REGULATION OF EXTENT OF CELL GROWTH 13 101 4.584e-05 0.001205
179 NEGATIVE CHEMOTAXIS 8 39 4.738e-05 0.001232
180 REGULATION OF OSSIFICATION 18 178 4.872e-05 0.001259
181 POSITIVE REGULATION OF MOLECULAR FUNCTION 93 1791 4.929e-05 0.001263
182 RESPONSE TO ABIOTIC STIMULUS 60 1024 4.94e-05 0.001263
183 REGULATION OF RESPONSE TO WOUNDING 31 413 5.046e-05 0.001276
184 CARDIOBLAST DIFFERENTIATION 5 13 5.026e-05 0.001276
185 REGULATION OF SECRETION 45 699 5.249e-05 0.00132
186 MODULATION OF SYNAPTIC TRANSMISSION 25 301 5.346e-05 0.001337
187 EMBRYO DEVELOPMENT 54 894 5.375e-05 0.001338
188 REGULATION OF CARTILAGE DEVELOPMENT 10 63 5.684e-05 0.001392
189 PEPTIDYL SERINE MODIFICATION 16 148 5.672e-05 0.001392
190 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 13 103 5.644e-05 0.001392
191 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 46 724 5.947e-05 0.001449
192 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 21 232 6.148e-05 0.00149
193 REGULATION OF CELL MATRIX ADHESION 12 90 6.289e-05 0.001516
194 REGULATION OF CELL CELL ADHESION 29 380 6.526e-05 0.001565
195 RESPONSE TO INORGANIC SUBSTANCE 34 479 6.784e-05 0.001619
196 MATERNAL PLACENTA DEVELOPMENT 7 31 7.397e-05 0.001756
197 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 44 689 7.643e-05 0.001805
198 RESPONSE TO ALKALOID 15 137 8.298e-05 0.00195
199 REGULATION OF SYNAPSE ASSEMBLY 11 79 8.461e-05 0.001969
200 BONE MORPHOGENESIS 11 79 8.461e-05 0.001969
201 REGULATION OF GROWTH 41 633 9.848e-05 0.00228
202 REGULATION OF CELL SIZE 17 172 0.000104 0.002396
203 NEGATIVE REGULATION OF RESPONSE TO WOUNDING 16 156 0.0001066 0.002444
204 CELLULAR RESPONSE TO HORMONE STIMULUS 37 552 0.0001077 0.002445
205 REGULATION OF CELL GROWTH 29 391 0.0001077 0.002445
206 ORGAN GROWTH 10 68 0.0001107 0.002476
207 CELLULAR RESPONSE TO STEROL 5 15 0.0001107 0.002476
208 REGULATION OF PROTEIN MODIFICATION PROCESS 88 1710 0.0001098 0.002476
209 STEM CELL DIFFERENTIATION 18 190 0.0001136 0.00253
210 REGULATION OF ANATOMICAL STRUCTURE SIZE 33 472 0.0001151 0.00255
211 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 9 56 0.0001205 0.002656
212 ION HOMEOSTASIS 38 576 0.000121 0.002656
213 SYNAPSE ASSEMBLY 10 69 0.0001255 0.002741
214 EPITHELIAL CELL DIFFERENTIATION 34 495 0.000128 0.002783
215 CELLULAR RESPONSE TO ACID CHEMICAL 17 175 0.0001286 0.002784
216 FOREBRAIN DEVELOPMENT 27 357 0.0001339 0.002857
217 RESPONSE TO STEROL 6 24 0.0001336 0.002857
218 CALCIUM ION TRANSMEMBRANE TRANSPORT 16 159 0.0001335 0.002857
219 CYCLIC NUCLEOTIDE METABOLIC PROCESS 9 57 0.0001387 0.002921
220 CAMP METABOLIC PROCESS 7 34 0.0001383 0.002921
221 ENDOCHONDRAL BONE MORPHOGENESIS 8 45 0.0001382 0.002921
222 EMBRYONIC MORPHOGENESIS 36 539 0.0001427 0.00299
223 REGULATION OF HORMONE LEVELS 33 478 0.0001457 0.00304
224 REGULATION OF STEM CELL DIFFERENTIATION 13 113 0.0001476 0.003065
225 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 24 303 0.0001556 0.003218
226 REGULATION OF ENDOTHELIAL CELL MIGRATION 13 114 0.0001614 0.003322
227 RESPONSE TO ESTRADIOL 15 146 0.0001702 0.00349
228 POSITIVE REGULATION OF TRANSPORT 54 936 0.0001748 0.003567
229 CELLULAR RESPONSE TO ALCOHOL 13 115 0.0001763 0.003582
230 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 18 197 0.0001795 0.003631
231 REGULATION OF GTPASE ACTIVITY 42 673 0.0001823 0.003672
232 COGNITION 21 251 0.000187 0.00375
233 REGULATION OF VASCULATURE DEVELOPMENT 20 233 0.0001878 0.00375
234 CHEMICAL HOMEOSTASIS 51 874 0.0002015 0.004008
235 EMBRYONIC ORGAN DEVELOPMENT 29 406 0.0002051 0.004061
236 CHONDROCYTE DIFFERENTIATION 9 60 0.0002079 0.004081
237 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 9 60 0.0002079 0.004081
238 CYCLIC NUCLEOTIDE CATABOLIC PROCESS 5 17 0.0002153 0.004141
239 REGULATION OF ENERGY HOMEOSTASIS 5 17 0.0002153 0.004141
240 REPLACEMENT OSSIFICATION 6 26 0.0002154 0.004141
241 ENDOCHONDRAL OSSIFICATION 6 26 0.0002154 0.004141
242 POSITIVE REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION 6 26 0.0002154 0.004141
243 REGULATION OF EPITHELIAL CELL MIGRATION 16 166 0.0002201 0.004214
244 REGULATION OF DENDRITE MORPHOGENESIS 10 74 0.000227 0.004329
245 POSITIVE REGULATION OF SYNAPSE ASSEMBLY 9 61 0.0002365 0.004472
246 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 17 184 0.0002356 0.004472
247 REGULATION OF ACTIN FILAMENT BASED PROCESS 24 312 0.0002414 0.004547
248 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 14 135 0.0002519 0.004727
249 REGULATION OF HEMOPOIESIS 24 314 0.0002653 0.004958
250 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 97 1977 0.0002696 0.005003
251 POSITIVE REGULATION OF CHEMOTAXIS 13 120 0.0002699 0.005003
252 REGULATION OF CELLULAR LOCALIZATION 68 1277 0.000272 0.005023
253 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 23 296 0.0002794 0.005138
254 LEUKOCYTE ACTIVATION 29 414 0.0002842 0.005206
255 RETINAL GANGLION CELL AXON GUIDANCE 5 18 0.0002897 0.005286
256 REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 8 50 0.0002956 0.005373
257 AMEBOIDAL TYPE CELL MIGRATION 15 154 0.0003058 0.005537
258 RHYTHMIC PROCESS 23 298 0.0003076 0.005548
259 REGULATION OF CELLULAR COMPONENT SIZE 25 337 0.0003137 0.005636
260 NEUROTRANSMITTER TRANSPORT 15 155 0.000328 0.00587
261 POSITIVE REGULATION OF ACUTE INFLAMMATORY RESPONSE 6 28 0.0003322 0.005922
262 CARDIAC MUSCLE TISSUE DEVELOPMENT 14 140 0.0003672 0.006516
263 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 44 740 0.0003683 0.006516
264 CALCIUM ION IMPORT 9 65 0.0003855 0.006794
265 CELL ACTIVATION 36 568 0.0003888 0.006801
266 REGULATION OF FEVER GENERATION 4 11 0.0003882 0.006801
267 RESPONSE TO MECHANICAL STIMULUS 18 210 0.0003935 0.006857
268 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 6 29 0.0004067 0.007061
269 NEURON MIGRATION 12 110 0.0004308 0.00743
270 REGULATION OF JNK CASCADE 15 159 0.0004311 0.00743
271 HEART MORPHOGENESIS 18 212 0.0004409 0.007571
272 RAS PROTEIN SIGNAL TRANSDUCTION 14 143 0.0004559 0.007799
273 REGULATION OF JUN KINASE ACTIVITY 10 81 0.0004778 0.008144
274 REGULATION OF LEUKOCYTE DIFFERENTIATION 19 232 0.0004854 0.008243
275 REGULATION OF OSTEOBLAST DIFFERENTIATION 12 112 0.0005081 0.008567
276 POSITIVE REGULATION OF LIPID METABOLIC PROCESS 13 128 0.000507 0.008567
277 SYNAPSE ORGANIZATION 14 145 0.0005248 0.008798
278 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 15 162 0.0005257 0.008798
279 CELLULAR RESPONSE TO EPINEPHRINE STIMULUS 4 12 0.0005663 0.009411
280 CELLULAR RESPONSE TO CHOLESTEROL 4 12 0.0005663 0.009411
281 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION 6 31 0.0005943 0.009841
282 REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY 12 114 0.0005968 0.009847
NumGOOverlapSizeP ValueAdj. P Value
1 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 51 629 1.736e-08 1.613e-05
2 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 30 315 6.098e-07 0.0001888
3 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 75 1199 4.81e-07 0.0001888
4 PROTEIN KINASE ACTIVITY 46 640 2.625e-06 0.0006095
5 REGULATORY REGION NUCLEIC ACID BINDING 54 818 4.564e-06 0.0007067
6 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 23 226 4.108e-06 0.0007067
7 GLYCOSAMINOGLYCAN BINDING 21 205 9.643e-06 0.0009953
8 RECEPTOR SIGNALING PROTEIN ACTIVITY 19 172 8.63e-06 0.0009953
9 RECEPTOR BINDING 83 1476 7.882e-06 0.0009953
10 CALCIUM ION BINDING 46 697 2.364e-05 0.002196
11 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 27 328 3.183e-05 0.002688
12 SIGNAL TRANSDUCER ACTIVITY 91 1731 3.812e-05 0.002951
13 PASSIVE TRANSMEMBRANE TRANSPORTER ACTIVITY 33 464 8.328e-05 0.005951
NumGOOverlapSizeP ValueAdj. P Value
1 NEURON PART 102 1265 7.486e-16 4.372e-13
2 NEURON PROJECTION 79 942 2.655e-13 7.752e-11
3 SYNAPSE 67 754 1.488e-12 2.897e-10
4 SOMATODENDRITIC COMPARTMENT 60 650 4.896e-12 7.148e-10
5 SYNAPSE PART 55 610 9.696e-11 1.132e-08
6 CELL PROJECTION 113 1786 1.862e-10 1.812e-08
7 CELL JUNCTION 81 1151 8.692e-10 7.251e-08
8 DENDRITE 43 451 2.162e-09 1.578e-07
9 CELL BODY 44 494 1.117e-08 6.602e-07
10 MEMBRANE REGION 77 1134 1.13e-08 6.602e-07
11 POSTSYNAPSE 36 378 4.611e-08 2.448e-06
12 AXON 38 418 6.667e-08 3.245e-06
13 EXCITATORY SYNAPSE 24 197 9.376e-08 3.911e-06
14 MEMBRANE MICRODOMAIN 30 288 8.719e-08 3.911e-06
15 CELL SURFACE 55 757 1.904e-07 7.411e-06
16 EXTRACELLULAR MATRIX 36 426 8.666e-07 3.163e-05
17 PROTEINACEOUS EXTRACELLULAR MATRIX 32 356 9.33e-07 3.205e-05
18 PRESYNAPSE 27 283 2.139e-06 6.941e-05
19 SECRETORY VESICLE 36 461 5.331e-06 0.0001588
20 PLASMA MEMBRANE REGION 59 929 5.438e-06 0.0001588
21 INTRINSIC COMPONENT OF PLASMA MEMBRANE 91 1649 5.865e-06 0.0001631
22 EXOCYTIC VESICLE 16 142 3.416e-05 0.0009067
23 SECRETORY GRANULE 27 352 0.000106 0.002318
24 EXTRACELLULAR MATRIX COMPONENT 14 125 0.0001111 0.002318
25 EXTRACELLULAR SPACE 74 1376 0.0001069 0.002318
26 SARCOLEMMA 14 125 0.0001111 0.002318
27 CELL LEADING EDGE 27 350 9.644e-05 0.002318
28 PLASMA MEMBRANE PROTEIN COMPLEX 35 510 0.000104 0.002318
29 CELL CELL JUNCTION 28 383 0.0001791 0.003607
30 VESICLE LUMEN 12 106 0.0003056 0.005949
31 BASEMENT MEMBRANE 11 93 0.0003686 0.006943
32 CELL PROJECTION PART 53 946 0.0004055 0.007401
33 NEURONAL POSTSYNAPTIC DENSITY 8 53 0.0004455 0.007884
34 PLATELET ALPHA GRANULE LUMEN 8 55 0.000576 0.00961
35 CYTOPLASMIC VESICLE PART 37 601 0.0005608 0.00961

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Apelin_signaling_pathway_hsa04371 18 137 1.241e-06 6.451e-05
2 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 15 139 9.792e-05 0.002315
3 cGMP_PKG_signaling_pathway_hsa04022 16 163 0.0001783 0.002315
4 Calcium_signaling_pathway_hsa04020 17 182 0.0002068 0.002315
5 MAPK_signaling_pathway_hsa04010 23 295 0.0002661 0.002315
6 Hippo_signaling_pathway_hsa04390 15 154 0.0003058 0.002315
7 Rap1_signaling_pathway_hsa04015 18 206 0.0003117 0.002315
8 Hippo_signaling_pathway_multiple_species_hsa04392 6 29 0.0004067 0.002644
9 Gap_junction_hsa04540 10 88 0.0009248 0.005343
10 ECM_receptor_interaction_hsa04512 9 82 0.0021 0.01092
11 Regulation_of_actin_cytoskeleton_hsa04810 16 208 0.002497 0.0118
12 Cytokine_cytokine_receptor_interaction_hsa04060 19 270 0.002867 0.01242
13 cAMP_signaling_pathway_hsa04024 15 198 0.003872 0.01507
14 Focal_adhesion_hsa04510 15 199 0.004058 0.01507
15 Cell_adhesion_molecules_.CAMs._hsa04514 12 145 0.004644 0.0161
16 Ras_signaling_pathway_hsa04014 16 232 0.00715 0.02324
17 Phospholipase_D_signaling_pathway_hsa04072 11 146 0.01285 0.03931
18 NF_kappa_B_signaling_pathway_hsa04064 8 95 0.01729 0.04995
19 PI3K_Akt_signaling_pathway_hsa04151 20 352 0.0215 0.05886
20 TGF_beta_signaling_pathway_hsa04350 7 84 0.02645 0.06876
21 Autophagy_animal_hsa04140 9 128 0.03411 0.08447
22 Jak_STAT_signaling_pathway_hsa04630 10 162 0.05581 0.1319
23 AMPK_signaling_pathway_hsa04152 8 121 0.0595 0.1321
24 Neuroactive_ligand_receptor_interaction_hsa04080 15 278 0.06098 0.1321
25 Oocyte_meiosis_hsa04114 8 124 0.0667 0.1387
26 ABC_transporters_hsa02010 4 45 0.06968 0.1394
27 FoxO_signaling_pathway_hsa04068 8 132 0.08842 0.1703
28 Adherens_junction_hsa04520 5 72 0.1042 0.1935
29 mTOR_signaling_pathway_hsa04150 8 151 0.1544 0.2768
30 ErbB_signaling_pathway_hsa04012 5 85 0.1721 0.2984
31 Cellular_senescence_hsa04218 8 160 0.192 0.322
32 Endocytosis_hsa04144 11 244 0.2276 0.3617
33 Notch_signaling_pathway_hsa04330 3 48 0.2314 0.3617
34 Tight_junction_hsa04530 8 170 0.2377 0.3617
35 Wnt_signaling_pathway_hsa04310 7 146 0.2435 0.3617
36 Autophagy_other_hsa04136 2 32 0.3049 0.4404
37 VEGF_signaling_pathway_hsa04370 3 59 0.3355 0.4715
38 Phagosome_hsa04145 6 152 0.4317 0.5908
39 HIF_1_signaling_pathway_hsa04066 4 100 0.4578 0.6104
40 Hedgehog_signaling_pathway_hsa04340 2 47 0.488 0.6344
41 Apoptosis_hsa04210 5 138 0.5234 0.6638
42 Mitophagy_animal_hsa04137 2 65 0.6637 0.8121
43 Phosphatidylinositol_signaling_system_hsa04070 3 99 0.6716 0.8121
44 p53_signaling_pathway_hsa04115 2 68 0.6877 0.8128
45 TNF_signaling_pathway_hsa04668 3 108 0.7275 0.8407
46 Lysosome_hsa04142 3 123 0.8038 0.9086
47 Sphingolipid_signaling_pathway_hsa04071 2 118 0.919 0.9846
48 Necroptosis_hsa04217 3 164 0.9266 0.9846
49 Cell_cycle_hsa04110 2 124 0.9318 0.9846

Quest ID: ab6ee548e12f4ada617f8873e0199073