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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-15a-5p BCL2 0.81 0 -0.9 0 miRNAWalker2 validate; miRTarBase -0.39 0 25594541; 22335947; 26915294; 18931683; 25623762 MicroRNAs miRNAs encoded by the miR-15 cluster are known to induce G1 arrest and apoptosis by targeting G1 checkpoints and the anti-apoptotic B cell lymphoma 2 BCL-2 gene;The expression of MiR-15a was significantly inhibited by Bcl-2 P < 0.05;As a result transcript levels of the tumor-suppressive miR-15 and let-7 families increased which targeted and decreased the expression of the crucial prosurvival genes BCL-2 and BCL-XL respectively;MicroRNAs miRNAs are noncoding small RNAs that repress protein translation by targeting specific messenger RNAs miR-15a and miR-16-1 act as putative tumor suppressors by targeting the oncogene BCL2;miR 15a and miR 16 modulate drug resistance by targeting bcl 2 in human colon cancer cells; To investigate the reversal effect of targeted modulation of bcl-2 expression by miR-15a and miR-16 on drug resistance of human colon cancer cells
2 hsa-miR-15b-3p BCL2 1.13 0 -0.9 0 mirMAP -0.31 0 25594541; 26915294; 26884837; 18449891 MicroRNAs miRNAs encoded by the miR-15 cluster are known to induce G1 arrest and apoptosis by targeting G1 checkpoints and the anti-apoptotic B cell lymphoma 2 BCL-2 gene;As a result transcript levels of the tumor-suppressive miR-15 and let-7 families increased which targeted and decreased the expression of the crucial prosurvival genes BCL-2 and BCL-XL respectively;MiR 15b mediates liver cancer cells proliferation through targeting BCL 2; MiR-15b overexpression downregulated BCL2 mRNA and protein expression obviously P < 0.05; On the contrary miR-15b inhibitor transfection markedly reduced miR-15b expression in liver cancer cells P < 0.05 promoted tumor cell proliferation and increased BCL2 mRNA and protein expression; MiR-15b can inhibit HepG2 cell proliferation and down-regulate BCL2 mRNA and protein expression;miR 15b and miR 16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells; The downregulation of miR-15b and miR-16 in SGC7901/VCR cells was concurrent with the upregulation of Bcl-2 protein; Taken together our findings suggest that miR-15b and miR-16 could play a role in the development of MDR in gastric cancer cells at least in part by modulation of apoptosis via targeting BCL2
3 hsa-miR-17-5p BCL2 0.6 1.0E-5 -0.9 0 miRNAWalker2 validate; miRTarBase -0.42 0 25435430 Combined overexpression of miR-16 and miR-17 greatly reduced Beclin-1 and Bcl-2 expressions respectively; miR-17 overexpression reduced cytoprotective autophagy by targeting Beclin-1 whereas overexpression of miR-16 potentiated paclitaxel induced apoptotic cell death by inhibiting anti-apoptotic protein Bcl-2
4 hsa-miR-181a-5p BCL2 0.64 0 -0.9 0 miRNAWalker2 validate; miRTarBase -0.4 0 24335172; 24267199; 23740615; 25524579; 27534652 The function role of miR 181a in chemosensitivity to adriamycin by targeting Bcl 2 in low invasive breast cancer cells; Luciferase reporter vector with the putative BCL-2 3' untranslated region 3'UTR was constructed to explore whether BCL-2 was a direct target gene of miR-181a; Real-time PCR was performed to test the expression of miR-181a and Bcl-2 in the selected breast cancer tissue samples; Transfected with miR-181a mimic in cells resulted in the decreased expression of Bcl-2; At least in part the detection of miR-181a may direct the clinical medication in patients with neoadjuvant chemotherapy because of miR-181a enhanced adriamycin-induced apoptosis via targeting Bcl-2;Bufalin was found to induce the expression of miR-181a a small non-coding RNA believed to induce apoptosis by repressing its target gene BCL-2; In prostate cancer PC-3cell line bufalin-induced apoptosis can be largely attenuated by a miR-181a inhibitor which blocked bufalin-induced Bcl-2 reduction and caspase-3 activation;The results from Western blotting indicated that miR-181a might be associated with the up-regulation of bcl-2 and matrix metalloproteinase 9 and the down-regulation of tissue inhibitor of metalloproteinases-3 and p21 in MG63 cells;Moreover we also found miR-181 reduction was associated with increased Bcl-2 levels and miR-181 was further suggested to exert its pro-apoptotic function mainly through targeting Bcl-2 expression;In addition inhibition of miR-181a promoted apoptosis of HeLa and CaSKi cells due to increasing Bax expression and decreasing Bcl-2 expression
5 hsa-miR-181b-5p BCL2 1.23 0 -0.9 0 miRNAWalker2 validate; miRTarBase -0.47 0 25524579 Moreover we also found miR-181 reduction was associated with increased Bcl-2 levels and miR-181 was further suggested to exert its pro-apoptotic function mainly through targeting Bcl-2 expression
6 hsa-miR-186-5p BCL2 -0.43 1.0E-5 -0.9 0 mirMAP -0.35 0 NA
7 hsa-miR-20a-5p BCL2 0.45 0.0006 -0.9 0 miRNAWalker2 validate; miRTarBase -0.4 0 NA
8 hsa-miR-21-5p BCL2 2.32 0 -0.9 0 miRNAWalker2 validate; miRTarBase -0.49 0 26555418; 21468550; 25994220; 25381586; 23359184; 22964582; 21376256 The expression of Bax Bcl-2 and miR-21 in parental and paclitaxel-resistant cells was detected by RT-PCR and Western blotting;BCL-2 up-regulation could be achieved by miR-21 overexpression which prevented T24 cells from apoptosis induced by doxorubicin; Furthermore the miR-21 induced BCL-2 up-regulation could be cancelled by the PI3K inhibitor LY294002;Meanwhile miR-21 loss reduced STAT3 and Bcl-2 activation causing an increase in the apoptosis of tumour cells in CAC mice;Changes in the sensitivity of osteosarcoma cells to CDDP were examined after transfection with miR-21 mimics or anti-miR-21 or bcl-2 siRNA in combination with CDDP;Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR 21 regulation of BCL 2 expression; We also used Western blot to measure BCL-2 protein levels after down-regulation of miR-21 expression; Besides down-regulation of miR-21 expression can inhibit BCL-2 expression in PANC-1 CFPAC-1 and MIA Paca-2 cells; Over-expression of miR-21 expression can reverse down-regulation of BCL-2 expression and apoptosis induced by resveratrol; In this study we demonstrated that the effect of resveratrol on apoptosis is due to inhibiting miR-21 regulation of BCL-2 expression;Tumors harvested from these lungs have elevated levels of oncogenic miRNAs miR-21 and miR-155; are deficient for p53-regulated miRNAs; and have heightened expression of miR-34 target genes such as Met and Bcl-2;Bcl 2 upregulation induced by miR 21 via a direct interaction is associated with apoptosis and chemoresistance in MIA PaCa 2 pancreatic cancer cells; However the roles and mechanisms of miRNA miR-21 in regulation of Bcl-2 in pancreatic cancer remain to be elucidated; Then luciferase activity was observed after miR-21 mimics and pRL-TK plasmids containing wild-type and mutant 3'UTRs of Bcl-2 mRNA were co-transfected; Cells transfected with miR-21 inhibitor revealed an opposite trend. There was a significant increase in luciferase activity in the cells transfected with the wild-type pRL-TK plasmid in contrast to those transfected with the mutant one indicating that miR-21 promotes Bcl-2 expression by binding directly to the 3'UTR of Bcl-2 mRNA; Upregulation of Bcl-2 directly induced by miR-21 is associated with apoptosis chemoresistance and proliferation of MIA PaCa-2 pancreatic cancer cells
9 hsa-miR-24-2-5p BCL2 -0.22 0.05957 -0.9 0 miRNAWalker2 validate; miRTarBase -0.31 0 NA
10 hsa-miR-374a-5p BCL2 -0.24 0.0031 -0.9 0 mirMAP -0.33 0 NA
11 hsa-miR-455-5p BCL2 0.28 0.03576 -0.9 0 mirMAP -0.41 0 NA
12 hsa-miR-590-3p BCL2 1.27 0 -0.9 0 miRanda; mirMAP -0.39 0 NA
13 hsa-miR-590-5p BCL2 0.75 0 -0.9 0 miRanda -0.43 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF CELL DEATH 269 1472 2.41e-87 1.121e-83
2 CELL DEATH 189 1001 7.408e-62 1.723e-58
3 RESPONSE TO OXYGEN CONTAINING COMPOUND 217 1381 7.207e-57 1.118e-53
4 POSITIVE REGULATION OF RESPONSE TO STIMULUS 262 1929 1.305e-56 1.519e-53
5 IMMUNE SYSTEM PROCESS 264 1984 2.812e-55 2.617e-52
6 CELLULAR RESPONSE TO STRESS 230 1565 3.742e-55 2.902e-52
7 REGULATION OF CELL PROLIFERATION 222 1496 8.312e-54 5.525e-51
8 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 250 1848 2.248e-53 1.308e-50
9 NEGATIVE REGULATION OF CELL DEATH 162 872 1.29e-51 6.672e-49
10 RESPONSE TO ABIOTIC STIMULUS 176 1024 3.628e-51 1.688e-48
11 RESPONSE TO LIPID 159 888 2.026e-48 8.571e-46
12 POSITIVE REGULATION OF CELL DEATH 129 605 1.014e-47 3.93e-45
13 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 208 1492 1.057e-45 3.785e-43
14 RESPONSE TO EXTERNAL STIMULUS 233 1821 4.223e-45 1.403e-42
15 REGULATION OF RESPONSE TO STRESS 203 1468 5.72e-44 1.774e-41
16 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 218 1656 6.138e-44 1.785e-41
17 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 227 1805 1.442e-42 3.947e-40
18 POSITIVE REGULATION OF GENE EXPRESSION 217 1733 3.185e-40 8.233e-38
19 RESPONSE TO ORGANIC CYCLIC COMPOUND 149 917 5.216e-40 1.277e-37
20 REGULATION OF IMMUNE SYSTEM PROCESS 188 1403 1.466e-38 3.306e-36
21 REGULATION OF PROTEIN MODIFICATION PROCESS 212 1710 1.492e-38 3.306e-36
22 POSITIVE REGULATION OF MOLECULAR FUNCTION 218 1791 1.751e-38 3.703e-36
23 REGULATION OF CELL CYCLE 148 949 1.359e-37 2.75e-35
24 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 184 1395 9.483e-37 1.838e-34
25 POSITIVE REGULATION OF CELL COMMUNICATION 194 1532 2.432e-36 4.526e-34
26 RESPONSE TO ENDOGENOUS STIMULUS 186 1450 1.642e-35 2.938e-33
27 RESPONSE TO BIOTIC STIMULUS 138 886 6.167e-35 1.063e-32
28 REGULATION OF APOPTOTIC SIGNALING PATHWAY 84 363 7.303e-34 1.214e-31
29 REGULATION OF PHOSPHORUS METABOLIC PROCESS 194 1618 4.811e-33 7.462e-31
30 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 78 321 4.664e-33 7.462e-31
31 RESPONSE TO CYTOKINE 119 714 6.44e-33 9.667e-31
32 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 126 799 2.101e-32 3.055e-30
33 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 132 867 2.341e-32 3.3e-30
34 DEFENSE RESPONSE 162 1231 4.768e-32 6.525e-30
35 POSITIVE REGULATION OF CELL PROLIFERATION 126 814 1.366e-31 1.816e-29
36 CELL PROLIFERATION 112 672 5.551e-31 7.174e-29
37 INTERSPECIES INTERACTION BETWEEN ORGANISMS 111 662 6.041e-31 7.397e-29
38 SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM 111 662 6.041e-31 7.397e-29
39 REGULATION OF TRANSFERASE ACTIVITY 136 946 1.035e-30 1.235e-28
40 CELL CYCLE 166 1316 1.21e-30 1.407e-28
41 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 192 1672 3.477e-30 3.946e-28
42 REGULATION OF CELLULAR LOCALIZATION 162 1277 3.624e-30 4.015e-28
43 RESPONSE TO OXYGEN LEVELS 73 311 5.951e-30 6.439e-28
44 REGULATION OF CELLULAR RESPONSE TO STRESS 112 691 7.087e-30 7.494e-28
45 REGULATION OF CYTOKINE PRODUCTION 99 563 2.485e-29 2.57e-27
46 IMMUNE RESPONSE 146 1100 3.379e-29 3.418e-27
47 REGULATION OF CELL ADHESION 105 629 4.051e-29 4.01e-27
48 PHOSPHORYLATION 155 1228 1.397e-28 1.354e-26
49 POSITIVE REGULATION OF CATALYTIC ACTIVITY 177 1518 1.651e-28 1.567e-26
50 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 135 983 1.888e-28 1.757e-26
51 CELL CYCLE PROCESS 143 1081 1.959e-28 1.787e-26
52 RESPONSE TO BACTERIUM 94 528 2.68e-28 2.398e-26
53 REGULATION OF PROTEOLYSIS 111 711 3.687e-28 3.237e-26
54 INTRACELLULAR SIGNAL TRANSDUCTION 180 1572 4.782e-28 4.12e-26
55 REGULATION OF CELL DIFFERENTIATION 174 1492 5.16e-28 4.365e-26
56 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 125 876 6.713e-28 5.578e-26
57 REGULATION OF TRANSPORT 196 1804 1.08e-27 8.812e-26
58 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 142 1087 1.148e-27 9.21e-26
59 MITOTIC CELL CYCLE 115 766 1.252e-27 9.875e-26
60 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 145 1135 3.04e-27 2.358e-25
61 REGULATION OF KINASE ACTIVITY 115 776 3.995e-27 3.047e-25
62 PROTEIN PHOSPHORYLATION 128 944 1.943e-26 1.458e-24
63 REGULATION OF CELL CYCLE PROCESS 94 558 2.018e-26 1.491e-24
64 RESPONSE TO ALCOHOL 74 362 2.77e-26 2.014e-24
65 REGULATION OF MITOTIC CELL CYCLE 85 468 2.832e-26 2.027e-24
66 REGULATION OF PROTEIN LOCALIZATION 128 950 3.539e-26 2.495e-24
67 LOCOMOTION 141 1114 4.498e-26 3.124e-24
68 RESPONSE TO HORMONE 123 893 4.983e-26 3.409e-24
69 REGULATION OF IMMUNE RESPONSE 120 858 5.407e-26 3.646e-24
70 TISSUE DEVELOPMENT 171 1518 9.032e-26 6.004e-24
71 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 142 1142 1.752e-25 1.148e-23
72 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 142 1152 4.191e-25 2.708e-23
73 RESPONSE TO OXIDATIVE STRESS 71 352 6.854e-25 4.368e-23
74 RESPONSE TO NITROGEN COMPOUND 118 859 7.122e-25 4.478e-23
75 CELLULAR RESPONSE TO DNA DAMAGE STIMULUS 106 720 8.609e-25 5.341e-23
76 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 157 1360 1.014e-24 6.211e-23
77 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 49 171 1.337e-24 8.082e-23
78 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 129 1004 1.913e-24 1.141e-22
79 RESPONSE TO STEROID HORMONE 85 497 2.039e-24 1.201e-22
80 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 200 1977 2.501e-24 1.455e-22
81 APOPTOTIC SIGNALING PATHWAY 63 289 4.134e-24 2.375e-22
82 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 186 1784 4.653e-24 2.64e-22
83 REGULATION OF ORGANELLE ORGANIZATION 141 1178 1.127e-23 6.32e-22
84 NEGATIVE REGULATION OF MOLECULAR FUNCTION 133 1079 1.672e-23 9.261e-22
85 POSITIVE REGULATION OF CELL DIFFERENTIATION 112 823 2.76e-23 1.499e-21
86 NEGATIVE REGULATION OF CELL CYCLE 77 433 2.771e-23 1.499e-21
87 HOMEOSTATIC PROCESS 152 1337 3.068e-23 1.641e-21
88 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 129 1036 3.397e-23 1.776e-21
89 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 129 1036 3.397e-23 1.776e-21
90 CELLULAR RESPONSE TO CYTOKINE STIMULUS 93 606 4.008e-23 2.072e-21
91 DNA METABOLIC PROCESS 106 758 5.418e-23 2.77e-21
92 REGULATION OF CELL CYCLE PHASE TRANSITION 64 321 2.97e-22 1.502e-20
93 POSITIVE REGULATION OF TRANSPORT 119 936 3.583e-22 1.793e-20
94 REGULATION OF CELL CELL ADHESION 70 380 3.681e-22 1.822e-20
95 POSITIVE REGULATION OF PROTEOLYSIS 68 363 5.579e-22 2.733e-20
96 INFLAMMATORY RESPONSE 77 454 5.713e-22 2.769e-20
97 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 162 1517 6.366e-22 3.054e-20
98 NEGATIVE REGULATION OF GENE EXPRESSION 160 1493 8.39e-22 3.984e-20
99 CELL CYCLE PHASE TRANSITION 56 255 1.013e-21 4.761e-20
100 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 78 470 1.215e-21 5.655e-20
101 REGULATION OF BINDING 59 283 1.285e-21 5.92e-20
102 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 117 926 1.397e-21 6.373e-20
103 REGULATION OF CELL ACTIVATION 79 484 1.907e-21 8.615e-20
104 RESPONSE TO REACTIVE OXYGEN SPECIES 48 191 1.993e-21 8.919e-20
105 NEGATIVE REGULATION OF CELL CYCLE PROCESS 50 214 9.107e-21 4.036e-19
106 RESPONSE TO RADIATION 71 413 1.12e-20 4.916e-19
107 REGULATION OF INTRACELLULAR TRANSPORT 90 621 1.132e-20 4.921e-19
108 CELLULAR RESPONSE TO LIPID 75 457 1.497e-20 6.449e-19
109 RESPONSE TO INORGANIC SUBSTANCE 77 479 1.619e-20 6.913e-19
110 REGULATION OF DEFENSE RESPONSE 101 759 2.503e-20 1.059e-18
111 CELL CYCLE CHECKPOINT 47 194 2.713e-20 1.137e-18
112 RESPONSE TO EXTRACELLULAR STIMULUS 73 441 2.991e-20 1.243e-18
113 POSITIVE REGULATION OF IMMUNE RESPONSE 84 563 3.67e-20 1.511e-18
114 POSITIVE REGULATION OF CELL CYCLE 62 332 4.583e-20 1.87e-18
115 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 140 1275 5.27e-20 2.132e-18
116 REGULATION OF CATABOLIC PROCESS 98 731 5.653e-20 2.267e-18
117 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 94 684 6.245e-20 2.484e-18
118 CELLULAR RESPONSE TO OXYGEN LEVELS 40 143 6.78e-20 2.673e-18
119 REGULATION OF HOMOTYPIC CELL CELL ADHESION 59 307 8.794e-20 3.438e-18
120 REGULATION OF CELL DEVELOPMENT 106 836 1.037e-19 4.02e-18
121 RESPONSE TO DRUG 71 431 1.329e-19 5.109e-18
122 POSITIVE REGULATION OF CYTOKINE PRODUCTION 65 370 1.584e-19 6.04e-18
123 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 119 1008 1.625e-19 6.147e-18
124 AGING 54 264 1.732e-19 6.499e-18
125 REGULATION OF MAPK CASCADE 91 660 2.046e-19 7.617e-18
126 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 48 213 2.748e-19 1.015e-17
127 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 87 616 2.83e-19 1.037e-17
128 NEGATIVE REGULATION OF CELL PROLIFERATION 89 643 4.064e-19 1.477e-17
129 EPITHELIUM DEVELOPMENT 113 945 5.564e-19 2.007e-17
130 CELL MOTILITY 104 835 8.75e-19 3.108e-17
131 LOCALIZATION OF CELL 104 835 8.75e-19 3.108e-17
132 REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY 39 145 9.006e-19 3.175e-17
133 PEPTIDYL AMINO ACID MODIFICATION 104 841 1.469e-18 5.064e-17
134 ORGAN MORPHOGENESIS 104 841 1.469e-18 5.064e-17
135 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 63 365 1.465e-18 5.064e-17
136 LEUKOCYTE MIGRATION 52 259 1.933e-18 6.612e-17
137 CELL ACTIVATION 81 568 2.907e-18 9.872e-17
138 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 45 199 3.177e-18 1.071e-16
139 NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 45 200 3.911e-18 1.309e-16
140 CELLULAR RESPONSE TO EXTERNAL STIMULUS 52 264 4.62e-18 1.535e-16
141 INTRINSIC APOPTOTIC SIGNALING PATHWAY 39 152 5.423e-18 1.789e-16
142 REGULATION OF CELLULAR PROTEIN LOCALIZATION 79 552 6.284e-18 2.055e-16
143 NEGATIVE REGULATION OF CELL COMMUNICATION 129 1192 6.315e-18 2.055e-16
144 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 116 1021 9.539e-18 3.082e-16
145 MITOTIC CELL CYCLE CHECKPOINT 37 139 1.029e-17 3.303e-16
146 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 99 801 1.101e-17 3.509e-16
147 CELLULAR RESPONSE TO BIOTIC STIMULUS 40 163 1.121e-17 3.549e-16
148 IMMUNE SYSTEM DEVELOPMENT 81 582 1.268e-17 3.986e-16
149 REGULATION OF PEPTIDASE ACTIVITY 64 392 1.407e-17 4.395e-16
150 INNATE IMMUNE RESPONSE 84 619 1.46e-17 4.53e-16
151 POSITIVE REGULATION OF CELL ACTIVATION 56 311 1.736e-17 5.351e-16
152 RESPONSE TO ESTROGEN 46 218 2.421e-17 7.412e-16
153 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 37 146 6.024e-17 1.832e-15
154 GLAND DEVELOPMENT 63 395 8.24e-17 2.49e-15
155 POSITIVE REGULATION OF CELL ADHESION 61 376 1.128e-16 3.387e-15
156 EXTRACELLULAR STRUCTURE ORGANIZATION 54 304 1.223e-16 3.647e-15
157 BIOLOGICAL ADHESION 114 1032 1.515e-16 4.491e-15
158 REPRODUCTION 133 1297 1.562e-16 4.6e-15
159 REGULATION OF CELLULAR COMPONENT MOVEMENT 94 771 1.901e-16 5.563e-15
160 REGULATION OF CYTOPLASMIC TRANSPORT 70 481 2.173e-16 6.32e-15
161 CARDIOVASCULAR SYSTEM DEVELOPMENT 95 788 2.688e-16 7.72e-15
162 CIRCULATORY SYSTEM DEVELOPMENT 95 788 2.688e-16 7.72e-15
163 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 98 829 3.205e-16 9.15e-15
164 CELL DEVELOPMENT 141 1426 3.6e-16 1.022e-14
165 CYTOKINE MEDIATED SIGNALING PATHWAY 67 452 3.836e-16 1.082e-14
166 DNA INTEGRITY CHECKPOINT 36 146 4.089e-16 1.146e-14
167 POSITIVE REGULATION OF LOCOMOTION 64 420 4.607e-16 1.284e-14
168 NEUROGENESIS 139 1402 4.85e-16 1.343e-14
169 VASCULATURE DEVELOPMENT 68 469 7.189e-16 1.979e-14
170 RESPONSE TO WOUNDING 76 563 7.391e-16 2.023e-14
171 CELLULAR RESPONSE TO NITROGEN COMPOUND 71 505 8.282e-16 2.253e-14
172 SINGLE ORGANISM CELL ADHESION 67 459 8.41e-16 2.275e-14
173 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 65 437 9.058e-16 2.436e-14
174 HOMEOSTASIS OF NUMBER OF CELLS 39 175 9.601e-16 2.553e-14
175 REGULATION OF PROTEIN CATABOLIC PROCESS 61 393 9.554e-16 2.553e-14
176 CELLULAR RESPONSE TO OXIDATIVE STRESS 40 184 1.015e-15 2.683e-14
177 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 80 616 1.136e-15 2.987e-14
178 CENTRAL NERVOUS SYSTEM DEVELOPMENT 100 872 1.17e-15 3.06e-14
179 PROTEIN COMPLEX SUBUNIT ORGANIZATION 146 1527 1.712e-15 4.45e-14
180 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 76 573 1.947e-15 5.005e-14
181 POSITIVE REGULATION OF CELL CELL ADHESION 46 243 1.938e-15 5.005e-14
182 POSITIVE REGULATION OF PEPTIDASE ACTIVITY 36 154 2.501e-15 6.395e-14
183 POSITIVE REGULATION OF KINASE ACTIVITY 68 482 2.904e-15 7.383e-14
184 MITOTIC DNA INTEGRITY CHECKPOINT 29 100 2.968e-15 7.507e-14
185 POSITIVE REGULATION OF CELL CYCLE PROCESS 46 247 3.681e-15 9.258e-14
186 REGULATION OF HYDROLASE ACTIVITY 131 1327 5.391e-15 1.349e-13
187 LYMPHOCYTE ACTIVATION 55 342 5.49e-15 1.366e-13
188 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 66 465 5.604e-15 1.387e-13
189 BLOOD VESSEL MORPHOGENESIS 57 364 5.773e-15 1.421e-13
190 EMBRYO DEVELOPMENT 100 894 5.94e-15 1.455e-13
191 RESPONSE TO TOXIC SUBSTANCE 45 241 6.66e-15 1.622e-13
192 REGULATION OF RESPONSE TO WOUNDING 61 413 9.93e-15 2.406e-13
193 LEUKOCYTE ACTIVATION 61 414 1.111e-14 2.679e-13
194 ACTIVATION OF IMMUNE RESPONSE 62 427 1.332e-14 3.195e-13
195 RESPONSE TO IONIZING RADIATION 34 145 1.354e-14 3.231e-13
196 RESPONSE TO GROWTH FACTOR 66 475 1.591e-14 3.776e-13
197 REGULATION OF MAP KINASE ACTIVITY 52 319 1.754e-14 4.142e-13
198 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 43 228 1.852e-14 4.351e-13
199 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 34 147 2.09e-14 4.887e-13
200 REGULATION OF CELL CYCLE ARREST 29 108 2.749e-14 6.397e-13
201 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 103 957 2.8e-14 6.482e-13
202 ORGANONITROGEN COMPOUND METABOLIC PROCESS 160 1796 3.136e-14 7.224e-13
203 NEGATIVE REGULATION OF CELL ADHESION 42 223 3.925e-14 8.997e-13
204 REGULATION OF PROTEIN BINDING 36 168 4.431e-14 1.008e-12
205 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 56 370 4.44e-14 1.008e-12
206 IMMUNE EFFECTOR PROCESS 66 486 4.818e-14 1.088e-12
207 RESPONSE TO UV 31 126 4.874e-14 1.095e-12
208 PROTEIN MATURATION 46 265 5.545e-14 1.24e-12
209 SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR 31 127 6.151e-14 1.369e-12
210 REGULATION OF DNA METABOLIC PROCESS 53 340 6.391e-14 1.416e-12
211 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 34 153 7.325e-14 1.615e-12
212 ZYMOGEN ACTIVATION 29 112 7.699e-14 1.69e-12
213 NEGATIVE REGULATION OF ORGANELLE ORGANIZATION 57 387 8.611e-14 1.881e-12
214 NEGATIVE REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY 26 90 8.949e-14 1.946e-12
215 CATABOLIC PROCESS 157 1773 9.553e-14 2.067e-12
216 POSITIVE REGULATION OF MAPK CASCADE 64 470 1.042e-13 2.244e-12
217 REGULATION OF OXIDATIVE STRESS INDUCED CELL DEATH 19 46 1.27e-13 2.724e-12
218 REGULATION OF CELL DIVISION 46 272 1.482e-13 3.164e-12
219 ANGIOGENESIS 48 293 1.497e-13 3.181e-12
220 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 67 514 2.218e-13 4.692e-12
221 TUBE DEVELOPMENT 70 552 2.449e-13 5.155e-12
222 REGULATION OF LEUKOCYTE PROLIFERATION 39 206 2.703e-13 5.665e-12
223 HEAD DEVELOPMENT 82 709 3.299e-13 6.884e-12
224 CELL DIVISION 62 460 4.063e-13 8.44e-12
225 REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 46 280 4.362e-13 9.02e-12
226 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 84 740 4.655e-13 9.584e-12
227 SIGNAL TRANSDUCTION IN RESPONSE TO DNA DAMAGE 26 96 4.774e-13 9.785e-12
228 LEUKOCYTE DIFFERENTIATION 47 292 5.223e-13 1.066e-11
229 CELLULAR HOMEOSTASIS 79 676 5.334e-13 1.084e-11
230 NEGATIVE REGULATION OF CYTOKINE PRODUCTION 39 211 5.998e-13 1.213e-11
231 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 53 360 6.633e-13 1.336e-11
232 REGULATION OF INFLAMMATORY RESPONSE 47 294 6.739e-13 1.352e-11
233 CELL CYCLE G2 M PHASE TRANSITION 31 138 6.806e-13 1.359e-11
234 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 47 296 8.673e-13 1.725e-11
235 RESPONSE TO ACID CHEMICAL 49 319 1.007e-12 1.994e-11
236 LEUKOCYTE CELL CELL ADHESION 43 255 1.029e-12 2.028e-11
237 REGULATION OF SECRETION 80 699 1.131e-12 2.22e-11
238 TISSUE MORPHOGENESIS 67 533 1.225e-12 2.395e-11
239 NEGATIVE REGULATION OF CELL DIFFERENTIATION 73 609 1.235e-12 2.405e-11
240 RESPONSE TO VIRUS 42 247 1.421e-12 2.755e-11
241 REGULATION OF DNA BINDING 25 93 1.612e-12 3.112e-11
242 REGULATION OF INNATE IMMUNE RESPONSE 52 357 1.674e-12 3.219e-11
243 RESPONSE TO LIGHT STIMULUS 45 280 1.733e-12 3.317e-11
244 REGULATION OF MITOCHONDRION ORGANIZATION 39 218 1.751e-12 3.339e-11
245 RESPONSE TO HYDROGEN PEROXIDE 27 109 1.758e-12 3.339e-11
246 REGENERATION 33 161 1.883e-12 3.561e-11
247 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 32 152 1.902e-12 3.583e-11
248 REGULATION OF RESPONSE TO OXIDATIVE STRESS 21 65 1.927e-12 3.615e-11
249 RESPONSE TO NUTRIENT 36 191 2.564e-12 4.791e-11
250 ACTIVATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 25 95 2.713e-12 5.017e-11
251 REPRODUCTIVE SYSTEM DEVELOPMENT 56 408 2.728e-12 5.017e-11
252 MACROMOLECULAR COMPLEX ASSEMBLY 128 1398 2.722e-12 5.017e-11
253 RESPONSE TO TOPOLOGICALLY INCORRECT PROTEIN 33 163 2.698e-12 5.017e-11
254 CELL CYCLE G1 S PHASE TRANSITION 27 111 2.803e-12 5.115e-11
255 G1 S TRANSITION OF MITOTIC CELL CYCLE 27 111 2.803e-12 5.115e-11
256 REGULATION OF NEURON DEATH 42 252 2.817e-12 5.12e-11
257 RESPONSE TO ESTRADIOL 31 146 3.327e-12 6.024e-11
258 NEGATIVE REGULATION OF CELL CELL ADHESION 30 138 3.927e-12 7.082e-11
259 POSITIVE REGULATION OF CELL DEVELOPMENT 61 472 3.953e-12 7.101e-11
260 REGULATION OF PROTEIN SECRETION 54 389 4.309e-12 7.711e-11
261 RESPONSE TO METAL ION 49 333 5.08e-12 9.056e-11
262 CELLULAR COMPONENT DISASSEMBLY 64 515 6.613e-12 1.175e-10
263 CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS 35 188 7.462e-12 1.32e-10
264 NEGATIVE REGULATION OF TRANSPORT 59 458 1.028e-11 1.812e-10
265 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 50 351 1.042e-11 1.83e-10
266 POSITIVE REGULATION OF CELL CYCLE ARREST 23 85 1.081e-11 1.89e-10
267 ORGANELLE FISSION 62 496 1.111e-11 1.935e-10
268 REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION 25 101 1.187e-11 2.061e-10
269 POSITIVE REGULATION OF DEFENSE RESPONSE 51 364 1.21e-11 2.093e-10
270 REGULATION OF EPITHELIAL CELL PROLIFERATION 44 285 1.232e-11 2.124e-10
271 RESPONSE TO KETONE 34 182 1.345e-11 2.31e-10
272 REGULATION OF NUCLEAR DIVISION 32 163 1.368e-11 2.341e-10
273 PROTEIN AUTOPHOSPHORYLATION 35 192 1.392e-11 2.373e-10
274 PROTEOLYSIS 113 1208 1.622e-11 2.755e-10
275 POSITIVE REGULATION OF HYDROLASE ACTIVITY 92 905 1.85e-11 3.13e-10
276 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 44 289 1.984e-11 3.344e-10
277 IMMUNE RESPONSE REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 47 323 2.068e-11 3.473e-10
278 MITOCHONDRION ORGANIZATION 69 594 2.223e-11 3.721e-10
279 CELL CELL ADHESION 70 608 2.382e-11 3.959e-10
280 CELLULAR RESPONSE TO REACTIVE OXYGEN SPECIES 25 104 2.375e-11 3.959e-10
281 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 76 689 2.599e-11 4.303e-10
282 REGULATION OF HEMOPOIESIS 46 314 2.679e-11 4.42e-10
283 MITOTIC NUCLEAR DIVISION 50 361 2.951e-11 4.851e-10
284 EPITHELIAL CELL DIFFERENTIATION 61 495 2.975e-11 4.874e-10
285 REGULATION OF CYTOKINE SECRETION 30 149 3.063e-11 5.001e-10
286 GLAND MORPHOGENESIS 24 97 3.085e-11 5.019e-10
287 NEGATIVE REGULATION OF PHOSPHORYLATION 55 422 3.336e-11 5.408e-10
288 DNA REPLICATION 36 208 3.369e-11 5.443e-10
289 REGULATION OF HOMEOSTATIC PROCESS 57 447 3.492e-11 5.622e-10
290 REGULATION OF IMMUNE EFFECTOR PROCESS 55 424 4.01e-11 6.434e-10
291 REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 42 274 4.57e-11 7.308e-10
292 TAXIS 58 464 5.227e-11 8.329e-10
293 INTERACTION WITH HOST 28 134 5.537e-11 8.794e-10
294 CELL CHEMOTAXIS 31 162 5.665e-11 8.94e-10
295 REGULATION OF GROWTH 71 633 5.668e-11 8.94e-10
296 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 38 233 5.994e-11 9.423e-10
297 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 29 144 6.487e-11 1.016e-09
298 POSITIVE REGULATION OF BINDING 27 127 8.026e-11 1.253e-09
299 WOUND HEALING 58 470 8.727e-11 1.358e-09
300 ESTABLISHMENT OF LOCALIZATION IN CELL 141 1676 8.938e-11 1.386e-09
301 CELLULAR RESPONSE TO ACID CHEMICAL 32 175 9.593e-11 1.483e-09
302 NEGATIVE REGULATION OF HOMOTYPIC CELL CELL ADHESION 24 102 9.631e-11 1.484e-09
303 RESPONSE TO GAMMA RADIATION 17 50 9.901e-11 1.52e-09
304 CELLULAR RESPONSE TO INORGANIC SUBSTANCE 30 156 1.016e-10 1.55e-09
305 POSITIVE REGULATION OF IMMUNE EFFECTOR PROCESS 30 156 1.016e-10 1.55e-09
306 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE 20 71 1.078e-10 1.64e-09
307 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 60 498 1.089e-10 1.65e-09
308 RESPONSE TO CORTICOSTEROID 32 176 1.119e-10 1.69e-09
309 MULTICELLULAR ORGANISM REPRODUCTION 80 768 1.296e-10 1.952e-09
310 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 36 218 1.334e-10 2.003e-09
311 RESPONSE TO PURINE CONTAINING COMPOUND 30 158 1.411e-10 2.112e-09
312 PROTEIN COMPLEX BIOGENESIS 105 1132 1.494e-10 2.221e-09
313 PROTEIN COMPLEX ASSEMBLY 105 1132 1.494e-10 2.221e-09
314 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 64 554 1.527e-10 2.258e-09
315 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 63 541 1.533e-10 2.258e-09
316 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 63 541 1.533e-10 2.258e-09
317 REGULATION OF STEM CELL DIFFERENTIATION 25 113 1.628e-10 2.389e-09
318 MYELOID CELL HOMEOSTASIS 22 88 1.644e-10 2.406e-09
319 CELLULAR RESPONSE TO ABIOTIC STIMULUS 40 263 1.688e-10 2.463e-09
320 MYELOID CELL DIFFERENTIATION 33 189 1.747e-10 2.54e-09
321 RESPONSE TO MECHANICAL STIMULUS 35 210 1.856e-10 2.69e-09
322 G1 DNA DAMAGE CHECKPOINT 20 73 1.873e-10 2.707e-09
323 DEFENSE RESPONSE TO OTHER ORGANISM 60 505 1.91e-10 2.751e-09
324 RHYTHMIC PROCESS 43 298 1.953e-10 2.805e-09
325 DNA REPAIR 58 480 2.002e-10 2.867e-09
326 POSITIVE REGULATION OF NF KAPPAB TRANSCRIPTION FACTOR ACTIVITY 27 132 2.033e-10 2.902e-09
327 RESPONSE TO HEAT 22 89 2.084e-10 2.966e-09
328 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 78 750 2.411e-10 3.421e-09
329 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 20 74 2.45e-10 3.465e-09
330 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 23 98 2.497e-10 3.51e-09
331 NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 23 98 2.497e-10 3.51e-09
332 CHROMOSOME ORGANIZATION 96 1009 2.559e-10 3.586e-09
333 REGULATION OF NEURON APOPTOTIC PROCESS 33 192 2.679e-10 3.733e-09
334 REGULATION OF SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR 30 162 2.676e-10 3.733e-09
335 REGULATION OF DNA TEMPLATED TRANSCRIPTION IN RESPONSE TO STRESS 19 67 2.777e-10 3.846e-09
336 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 49 372 2.77e-10 3.846e-09
337 VIRAL LIFE CYCLE 42 290 2.828e-10 3.904e-09
338 POSITIVE REGULATION OF HEMOPOIESIS 30 163 3.129e-10 4.307e-09
339 RESPONSE TO INTERFERON GAMMA 28 144 3.258e-10 4.471e-09
340 POSTTRANSCRIPTIONAL REGULATION OF GENE EXPRESSION 55 448 3.287e-10 4.499e-09
341 ORGAN REGENERATION 21 83 3.359e-10 4.584e-09
342 CELLULAR RESPONSE TO HORMONE STIMULUS 63 552 3.513e-10 4.779e-09
343 NEGATIVE REGULATION OF RESPONSE TO OXIDATIVE STRESS 14 35 3.661e-10 4.952e-09
344 NEGATIVE REGULATION OF CELLULAR RESPONSE TO OXIDATIVE STRESS 14 35 3.661e-10 4.952e-09
345 MORPHOGENESIS OF AN EPITHELIUM 51 400 3.854e-10 5.198e-09
346 MITOCHONDRIAL MEMBRANE ORGANIZATION 22 92 4.156e-10 5.589e-09
347 POSITIVE REGULATION OF MAP KINASE ACTIVITY 34 207 5.031e-10 6.746e-09
348 MULTI ORGANISM REPRODUCTIVE PROCESS 87 891 5.263e-10 7.037e-09
349 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 33 197 5.352e-10 7.135e-09
350 OSSIFICATION 38 251 5.53e-10 7.351e-09
351 POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 14 36 5.722e-10 7.585e-09
352 RESPONSE TO TEMPERATURE STIMULUS 28 148 6.308e-10 8.338e-09
353 NEGATIVE REGULATION OF CELL ACTIVATION 29 158 6.599e-10 8.698e-09
354 CYTOSKELETON ORGANIZATION 83 838 6.824e-10 8.97e-09
355 MACROMOLECULE CATABOLIC PROCESS 89 926 7.301e-10 9.57e-09
356 LIPOPOLYSACCHARIDE MEDIATED SIGNALING PATHWAY 13 31 7.759e-10 1.014e-08
357 TUBE MORPHOGENESIS 44 323 7.816e-10 1.019e-08
358 REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 15 43 8.331e-10 1.083e-08
359 ACTIVATION OF PROTEIN KINASE ACTIVITY 40 279 1.019e-09 1.321e-08
360 POSITIVE REGULATION OF MITOTIC CELL CYCLE 25 123 1.091e-09 1.407e-08
361 MULTI MULTICELLULAR ORGANISM PROCESS 34 213 1.092e-09 1.407e-08
362 NEGATIVE REGULATION OF CATABOLIC PROCESS 33 203 1.187e-09 1.526e-08
363 REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 22 97 1.229e-09 1.575e-08
364 REGULATION OF PROTEIN IMPORT 31 183 1.343e-09 1.717e-08
365 NEGATIVE REGULATION OF PROTEOLYSIS 44 329 1.404e-09 1.79e-08
366 RESPONSE TO VITAMIN 22 98 1.512e-09 1.922e-08
367 RESPONSE TO PEPTIDE 50 404 1.608e-09 2.038e-08
368 POSITIVE REGULATION OF DNA METABOLIC PROCESS 31 185 1.766e-09 2.233e-08
369 GLIOGENESIS 30 175 1.846e-09 2.328e-08
370 EXTRINSIC APOPTOTIC SIGNALING PATHWAY 22 99 1.855e-09 2.333e-08
371 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 48 381 1.898e-09 2.38e-08
372 LEUKOCYTE CHEMOTAXIS 24 117 1.929e-09 2.407e-08
373 REGULATION OF MULTI ORGANISM PROCESS 55 470 1.929e-09 2.407e-08
374 PEPTIDYL TYROSINE MODIFICATION 31 186 2.022e-09 2.516e-08
375 RESPONSE TO ALKALOID 26 137 2.396e-09 2.973e-08
376 LEUKOCYTE HOMEOSTASIS 17 60 2.45e-09 3.032e-08
377 REGULATION OF T CELL PROLIFERATION 27 147 2.512e-09 3.1e-08
378 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 58 513 2.549e-09 3.138e-08
379 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 34 220 2.59e-09 3.179e-08
380 GROWTH 50 410 2.658e-09 3.255e-08
381 REGULATION OF NEURON DIFFERENTIATION 61 554 2.736e-09 3.342e-08
382 FORMATION OF PRIMARY GERM LAYER 23 110 2.825e-09 3.441e-08
383 REGULATION OF LEUKOCYTE DIFFERENTIATION 35 232 2.909e-09 3.534e-08
384 POSITIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 30 179 3.208e-09 3.887e-08
385 REGULATION OF VASCULATURE DEVELOPMENT 35 233 3.266e-09 3.947e-08
386 POSITIVE REGULATION OF INNATE IMMUNE RESPONSE 36 246 3.995e-09 4.816e-08
387 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 33 213 4.157e-09 4.999e-08
388 REGULATION OF OXIDATIVE STRESS INDUCED INTRINSIC APOPTOTIC SIGNALING PATHWAY 12 29 4.242e-09 5.087e-08
389 NEGATIVE REGULATION OF BINDING 25 131 4.304e-09 5.148e-08
390 POSITIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 31 192 4.456e-09 5.309e-08
391 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 64 602 4.462e-09 5.309e-08
392 REGULATION OF MEMBRANE PERMEABILITY 18 70 4.629e-09 5.495e-08
393 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 39 282 4.668e-09 5.513e-08
394 CELLULAR RESPONSE TO INTERFERON GAMMA 24 122 4.66e-09 5.513e-08
395 RESPONSE TO AMINE 15 48 4.774e-09 5.624e-08
396 CHEMICAL HOMEOSTASIS 83 874 4.957e-09 5.81e-08
397 NEURON DIFFERENTIATION 83 874 4.957e-09 5.81e-08
398 MOVEMENT IN ENVIRONMENT OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 20 87 5.394e-09 6.182e-08
399 ENTRY INTO CELL OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 20 87 5.394e-09 6.182e-08
400 VIRAL ENTRY INTO HOST CELL 20 87 5.394e-09 6.182e-08
401 ENTRY INTO OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 20 87 5.394e-09 6.182e-08
402 MOVEMENT IN HOST ENVIRONMENT 20 87 5.394e-09 6.182e-08
403 ORGANONITROGEN COMPOUND BIOSYNTHETIC PROCESS 93 1024 5.291e-09 6.182e-08
404 ENTRY INTO HOST 20 87 5.394e-09 6.182e-08
405 REGULATION OF PROTEIN TARGETING 41 307 5.325e-09 6.182e-08
406 ENTRY INTO HOST CELL 20 87 5.394e-09 6.182e-08
407 AUTOPHAGY 48 394 5.727e-09 6.547e-08
408 NEGATIVE REGULATION OF KINASE ACTIVITY 36 250 6.19e-09 7.059e-08
409 POSITIVE REGULATION OF SECRETION 46 370 6.297e-09 7.164e-08
410 ANATOMICAL STRUCTURE HOMEOSTASIS 39 285 6.314e-09 7.165e-08
411 CELLULAR RESPONSE TO HEAT 13 36 6.916e-09 7.83e-08
412 REGULATION OF INTERFERON GAMMA PRODUCTION 21 97 7.116e-09 8.037e-08
413 POSITIVE REGULATION OF PROTEIN CATABOLIC PROCESS 37 263 7.257e-09 8.176e-08
414 IN UTERO EMBRYONIC DEVELOPMENT 41 311 7.787e-09 8.752e-08
415 MEMBRANE ORGANIZATION 84 899 8.452e-09 9.476e-08
416 LYMPHOCYTE HOMEOSTASIS 15 50 8.965e-09 1e-07
417 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 15 50 8.965e-09 1e-07
418 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 43 337 9.062e-09 1.009e-07
419 RESPONSE TO ETHANOL 25 136 9.565e-09 1.06e-07
420 POSITIVE REGULATION OF ADAPTIVE IMMUNE RESPONSE 18 73 9.55e-09 1.06e-07
421 MITOCHONDRIAL TRANSPORT 29 177 9.947e-09 1.099e-07
422 REGULATION OF CHROMOSOME ORGANIZATION 38 278 1.017e-08 1.122e-07
423 REGULATION OF BODY FLUID LEVELS 56 506 1.035e-08 1.138e-07
424 DNA DEPENDENT DNA REPLICATION 21 99 1.047e-08 1.149e-07
425 POSITIVE REGULATION OF MITOCHONDRION ORGANIZATION 28 167 1.058e-08 1.156e-07
426 MORPHOGENESIS OF A BRANCHING STRUCTURE 28 167 1.058e-08 1.156e-07
427 SENSORY ORGAN DEVELOPMENT 55 493 1.061e-08 1.156e-07
428 REGULATION OF PROTEIN STABILITY 33 221 1.065e-08 1.158e-07
429 RESPONSE TO ENDOPLASMIC RETICULUM STRESS 34 233 1.159e-08 1.257e-07
430 REGULATION OF RELEASE OF CYTOCHROME C FROM MITOCHONDRIA 14 44 1.2e-08 1.299e-07
431 SKIN DEVELOPMENT 32 211 1.211e-08 1.307e-07
432 CELLULAR CATABOLIC PROCESS 111 1322 1.302e-08 1.4e-07
433 RESPONSE TO TRANSITION METAL NANOPARTICLE 26 148 1.303e-08 1.4e-07
434 REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 44 354 1.355e-08 1.453e-07
435 ANTIGEN PROCESSING AND PRESENTATION 32 213 1.528e-08 1.634e-07
436 CELL REDOX HOMEOSTASIS 17 67 1.543e-08 1.646e-07
437 EMBRYONIC MORPHOGENESIS 58 539 1.559e-08 1.66e-07
438 POSITIVE REGULATION OF CATABOLIC PROCESS 47 395 1.741e-08 1.85e-07
439 FOREBRAIN DEVELOPMENT 44 357 1.748e-08 1.853e-07
440 REGULATION OF CELLULAR COMPONENT BIOGENESIS 74 767 1.826e-08 1.931e-07
441 NEGATIVE REGULATION OF CELL DIVISION 16 60 1.887e-08 1.991e-07
442 EXTRACELLULAR MATRIX DISASSEMBLY 18 76 1.893e-08 1.993e-07
443 ACTIVATION OF INNATE IMMUNE RESPONSE 31 204 1.947e-08 2.045e-07
444 REGULATION OF CYTOSKELETON ORGANIZATION 55 502 1.99e-08 2.086e-07
445 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 24 131 2.017e-08 2.109e-07
446 RESPONSE TO AMINO ACID 22 112 2.091e-08 2.182e-07
447 REGULATION OF CHROMOSOME SEGREGATION 19 85 2.119e-08 2.206e-07
448 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 37 274 2.203e-08 2.288e-07
449 REGULATION OF CYTOKINE BIOSYNTHETIC PROCESS 20 94 2.215e-08 2.296e-07
450 POSITIVE REGULATION OF CD4 POSITIVE ALPHA BETA T CELL ACTIVATION 11 27 2.314e-08 2.387e-07
451 REGULATION OF TRANSCRIPTION INVOLVED IN G1 S TRANSITION OF MITOTIC CELL CYCLE 11 27 2.314e-08 2.387e-07
452 REGULATION OF INTERLEUKIN 6 PRODUCTION 21 104 2.628e-08 2.705e-07
453 REGULATION OF METAL ION TRANSPORT 41 325 2.774e-08 2.849e-07
454 POSITIVE REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 30 196 2.781e-08 2.85e-07
455 NEURON DEATH 14 47 3.109e-08 3.179e-07
456 POSITIVE REGULATION OF TYPE I INTERFERON PRODUCTION 17 70 3.138e-08 3.202e-07
457 NEGATIVE REGULATION OF CHROMOSOME ORGANIZATION 20 96 3.23e-08 3.288e-07
458 RESPONSE TO INTERLEUKIN 1 22 115 3.46e-08 3.505e-07
459 CELLULAR RESPONSE TO ALCOHOL 22 115 3.46e-08 3.505e-07
460 LYMPHOCYTE DIFFERENTIATION 31 209 3.465e-08 3.505e-07
461 GASTRULATION 26 155 3.492e-08 3.525e-07
462 SINGLE ORGANISM CELLULAR LOCALIZATION 82 898 3.559e-08 3.584e-07
463 MULTICELLULAR ORGANISMAL MACROMOLECULE METABOLIC PROCESS 18 79 3.62e-08 3.638e-07
464 REGULATION OF CELL MORPHOGENESIS 58 552 3.641e-08 3.651e-07
465 REGULATION OF PEPTIDE TRANSPORT 35 256 3.848e-08 3.851e-07
466 ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE ANTIGEN 28 177 3.895e-08 3.889e-07
467 REGULATION OF LEUKOCYTE MEDIATED IMMUNITY 26 156 3.999e-08 3.976e-07
468 NEGATIVE REGULATION OF RESPONSE TO WOUNDING 26 156 3.999e-08 3.976e-07
469 MUSCLE STRUCTURE DEVELOPMENT 49 432 4.026e-08 3.995e-07
470 NEGATIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 24 136 4.285e-08 4.233e-07
471 POSITIVE REGULATION OF LEUKOCYTE PROLIFERATION 24 136 4.285e-08 4.233e-07
472 CELLULAR RESPONSE TO MECHANICAL STIMULUS 18 80 4.46e-08 4.396e-07
473 NEURON APOPTOTIC PROCESS 12 35 5.193e-08 5.108e-07
474 REGULATION OF CELL PROJECTION ORGANIZATION 58 558 5.319e-08 5.221e-07
475 REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 11 29 5.61e-08 5.484e-07
476 POSITIVE REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 11 29 5.61e-08 5.484e-07
477 REGULATION OF OXIDOREDUCTASE ACTIVITY 19 90 5.672e-08 5.521e-07
478 REGULATION OF GLIOGENESIS 19 90 5.672e-08 5.521e-07
479 PLACENTA DEVELOPMENT 24 138 5.727e-08 5.563e-07
480 SMALL MOLECULE METABOLIC PROCESS 136 1767 5.769e-08 5.592e-07
481 NEGATIVE REGULATION OF PROTEIN CATABOLIC PROCESS 21 109 6.209e-08 5.994e-07
482 PATTERN RECOGNITION RECEPTOR SIGNALING PATHWAY 21 109 6.209e-08 5.994e-07
483 REGULATION OF LEUKOCYTE MIGRATION 25 149 6.344e-08 6.112e-07
484 RESPONSE TO ORGANOPHOSPHORUS 24 139 6.607e-08 6.351e-07
485 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 23 129 6.7e-08 6.428e-07
486 CELLULAR RESPONSE TO PEPTIDE 36 274 6.919e-08 6.624e-07
487 NEGATIVE REGULATION OF NEURON DEATH 27 171 7.064e-08 6.75e-07
488 ADAPTIVE IMMUNE RESPONSE 37 288 8.202e-08 7.82e-07
489 REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 19 92 8.234e-08 7.835e-07
490 REGULATION OF TYPE I INTERFERON PRODUCTION 21 111 8.623e-08 8.188e-07
491 ANTIGEN RECEPTOR MEDIATED SIGNALING PATHWAY 29 195 8.982e-08 8.506e-07
492 POSITIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 23 131 8.994e-08 8.506e-07
493 REGULATION OF INTERLEUKIN 12 PRODUCTION 14 51 9.793e-08 9.224e-07
494 POSITIVE REGULATION OF ALPHA BETA T CELL ACTIVATION 14 51 9.793e-08 9.224e-07
495 REGULATION OF ORGAN MORPHOGENESIS 33 242 9.979e-08 9.381e-07
496 CELLULAR RESPONSE TO TOPOLOGICALLY INCORRECT PROTEIN 22 122 1.045e-07 9.8e-07
497 PROTEIN LOCALIZATION TO ORGANELLE 57 556 1.111e-07 1.038e-06
498 CELLULAR CHEMICAL HOMEOSTASIS 58 570 1.11e-07 1.038e-06
499 CELLULAR MACROMOLECULE LOCALIZATION 102 1234 1.159e-07 1.081e-06
500 GLYCOSYL COMPOUND METABOLIC PROCESS 43 368 1.184e-07 1.102e-06
501 TOLL LIKE RECEPTOR SIGNALING PATHWAY 18 85 1.202e-07 1.114e-06
502 POSITIVE REGULATION OF LEUKOCYTE MEDIATED IMMUNITY 18 85 1.202e-07 1.114e-06
503 REGULATION OF CALCIUM ION TRANSPORT 30 209 1.209e-07 1.118e-06
504 REGULATION OF ADAPTIVE IMMUNE RESPONSE 22 123 1.214e-07 1.121e-06
505 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 25 154 1.233e-07 1.136e-06
506 REGULATION OF ALPHA BETA T CELL ACTIVATION 16 68 1.282e-07 1.176e-06
507 POSITIVE REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY 14 52 1.28e-07 1.176e-06
508 RESPONSE TO TUMOR NECROSIS FACTOR 32 233 1.316e-07 1.205e-06
509 REGULATION OF MONOOXYGENASE ACTIVITY 15 60 1.338e-07 1.22e-06
510 MATERNAL PROCESS INVOLVED IN FEMALE PREGNANCY 15 60 1.338e-07 1.22e-06
511 SINGLE ORGANISM CATABOLIC PROCESS 84 957 1.362e-07 1.24e-06
512 ANAPHASE PROMOTING COMPLEX DEPENDENT CATABOLIC PROCESS 17 77 1.414e-07 1.285e-06
513 REGULATION OF CD4 POSITIVE ALPHA BETA T CELL ACTIVATION 12 38 1.47e-07 1.334e-06
514 OXIDATION REDUCTION PROCESS 80 898 1.491e-07 1.35e-06
515 NEGATIVE REGULATION OF CELLULAR CATABOLIC PROCESS 25 156 1.595e-07 1.441e-06
516 POSITIVE REGULATION OF FIBROBLAST PROLIFERATION 14 53 1.662e-07 1.499e-06
517 REACTIVE OXYGEN SPECIES METABOLIC PROCESS 19 96 1.679e-07 1.511e-06
518 PROTEIN FOLDING 31 224 1.732e-07 1.556e-06
519 REGULATION OF ION TRANSPORT 59 592 1.766e-07 1.583e-06
520 POSITIVE REGULATION OF MULTI ORGANISM PROCESS 25 157 1.81e-07 1.62e-06
521 POSITIVE REGULATION OF EPIDERMIS DEVELOPMENT 11 32 1.827e-07 1.626e-06
522 GLIAL CELL DIFFERENTIATION 23 136 1.827e-07 1.626e-06
523 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 11 32 1.827e-07 1.626e-06
524 REGULATION OF INTERLEUKIN 10 PRODUCTION 13 46 1.93e-07 1.71e-06
525 NEGATIVE REGULATION OF NUCLEAR DIVISION 13 46 1.93e-07 1.71e-06
526 MUSCLE CELL DIFFERENTIATION 32 237 1.956e-07 1.731e-06
527 REGULATION OF AUTOPHAGY 33 249 1.969e-07 1.738e-06
528 CELLULAR RESPONSE TO RADIATION 23 137 2.095e-07 1.843e-06
529 ACTIVATION OF MAPK ACTIVITY 23 137 2.095e-07 1.843e-06
530 REGULATION OF PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 24 148 2.241e-07 1.963e-06
531 PEPTIDYL SERINE MODIFICATION 24 148 2.241e-07 1.963e-06
532 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 45 404 2.431e-07 2.126e-06
533 REGULATION OF CELL GROWTH 44 391 2.478e-07 2.159e-06
534 EYE DEVELOPMENT 39 326 2.477e-07 2.159e-06
535 POSITIVE REGULATION OF HOMEOSTATIC PROCESS 30 216 2.52e-07 2.192e-06
536 B CELL HOMEOSTASIS 9 21 2.683e-07 2.316e-06
537 REGULATION OF EPIDERMIS DEVELOPMENT 15 63 2.676e-07 2.316e-06
538 DECIDUALIZATION 9 21 2.683e-07 2.316e-06
539 NEGATIVE REGULATION OF OXIDATIVE STRESS INDUCED INTRINSIC APOPTOTIC SIGNALING PATHWAY 9 21 2.683e-07 2.316e-06
540 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 45 406 2.799e-07 2.407e-06
541 EMBRYONIC ORGAN DEVELOPMENT 45 406 2.799e-07 2.407e-06
542 BEHAVIOR 53 516 2.929e-07 2.515e-06
543 REGULATION OF FIBROBLAST PROLIFERATION 17 81 3.078e-07 2.638e-06
544 REGULATION OF CELL SUBSTRATE ADHESION 26 173 3.341e-07 2.857e-06
545 PROTEIN LOCALIZATION 135 1805 3.386e-07 2.891e-06
546 ERYTHROCYTE HOMEOSTASIS 16 73 3.652e-07 3.112e-06
547 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 29 208 3.665e-07 3.117e-06
548 REGULATION OF MUSCLE CELL DIFFERENTIATION 24 152 3.725e-07 3.162e-06
549 PROTEIN STABILIZATION 22 131 3.809e-07 3.228e-06
550 DNA BIOSYNTHETIC PROCESS 21 121 3.958e-07 3.349e-06
551 REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 15 65 4.145e-07 3.494e-06
552 POSITIVE REGULATION OF INTERFERON GAMMA PRODUCTION 15 65 4.145e-07 3.494e-06
553 DEVELOPMENTAL GROWTH 39 333 4.298e-07 3.617e-06
554 NECROTIC CELL DEATH 10 28 4.419e-07 3.707e-06
555 POSITIVE REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION 14 57 4.43e-07 3.707e-06
556 APOPTOTIC MITOCHONDRIAL CHANGES 14 57 4.43e-07 3.707e-06
557 CARBOHYDRATE DERIVATIVE METABOLIC PROCESS 88 1047 4.509e-07 3.767e-06
558 NEGATIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 12 42 5.009e-07 4.162e-06
559 POSITIVE REGULATION OF DNA BINDING 12 42 5.009e-07 4.162e-06
560 MULTICELLULAR ORGANISM METABOLIC PROCESS 18 93 5.01e-07 4.162e-06
561 MULTICELLULAR ORGANISMAL HOMEOSTASIS 34 272 5.224e-07 4.333e-06
562 NEGATIVE REGULATION OF DEFENSE RESPONSE 23 144 5.26e-07 4.355e-06
563 POSITIVE REGULATION OF ION TRANSPORT 31 236 5.585e-07 4.615e-06
564 REGULATION OF RESPONSE TO DNA DAMAGE STIMULUS 23 145 5.967e-07 4.923e-06
565 DEFENSE RESPONSE TO BACTERIUM 31 237 6.131e-07 5.049e-06
566 POSITIVE REGULATION OF PROTEIN IMPORT 19 104 6.202e-07 5.099e-06
567 POSITIVE REGULATION OF NEURON DEATH 15 67 6.306e-07 5.157e-06
568 CELL AGING 15 67 6.306e-07 5.157e-06
569 REGULATION OF SISTER CHROMATID SEGREGATION 15 67 6.306e-07 5.157e-06
570 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 33 262 6.434e-07 5.252e-06
571 REGULATION OF ERK1 AND ERK2 CASCADE 31 238 6.726e-07 5.481e-06
572 LEUKOCYTE APOPTOTIC PROCESS 9 23 6.826e-07 5.552e-06
573 NUCLEOSIDE MONOPHOSPHATE METABOLIC PROCESS 31 239 7.374e-07 5.988e-06
574 POSITIVE REGULATION OF INTERLEUKIN 6 PRODUCTION 15 68 7.728e-07 6.265e-06
575 CELLULAR TRANSITION METAL ION HOMEOSTASIS 16 77 7.878e-07 6.375e-06
576 TELENCEPHALON DEVELOPMENT 30 228 8.167e-07 6.598e-06
577 NEGATIVE REGULATION OF CELL DEVELOPMENT 36 303 8.415e-07 6.786e-06
578 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 66 724 8.553e-07 6.886e-06
579 PROTEIN AUTOPROCESSING 7 13 8.726e-07 7.013e-06
580 REGULATION OF SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM 28 205 8.854e-07 7.103e-06
581 NEGATIVE REGULATION OF LEUKOCYTE PROLIFERATION 15 69 9.432e-07 7.541e-06
582 MITOTIC SPINDLE ORGANIZATION 15 69 9.432e-07 7.541e-06
583 LYMPHOCYTE COSTIMULATION 16 78 9.466e-07 7.552e-06
584 TISSUE HOMEOSTASIS 25 171 9.479e-07 7.552e-06
585 PROTEIN CATABOLIC PROCESS 56 579 9.503e-07 7.559e-06
586 NEGATIVE REGULATION OF HYDROLASE ACTIVITY 43 397 9.571e-07 7.599e-06
587 POSITIVE REGULATION OF ALPHA BETA T CELL DIFFERENTIATION 11 37 9.664e-07 7.661e-06
588 FC RECEPTOR SIGNALING PATHWAY 28 206 9.778e-07 7.724e-06
589 REGULATION OF T CELL DIFFERENTIATION 19 107 9.763e-07 7.724e-06
590 HEART DEVELOPMENT 48 466 9.801e-07 7.729e-06
591 SINGLE ORGANISM BEHAVIOR 42 384 9.889e-07 7.786e-06
592 HEPATICOBILIARY SYSTEM DEVELOPMENT 21 128 1.036e-06 8.119e-06
593 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION 21 128 1.036e-06 8.119e-06
594 ENDOCYTOSIS 51 509 1.034e-06 8.119e-06
595 REGULATION OF ANOIKIS 9 24 1.045e-06 8.17e-06
596 REGULATION OF MICROTUBULE BASED PROCESS 31 243 1.059e-06 8.268e-06
597 REGULATION OF COAGULATION 17 88 1.064e-06 8.278e-06
598 REGULATION OF STEM CELL PROLIFERATION 17 88 1.064e-06 8.278e-06
599 NEGATIVE REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 22 139 1.084e-06 8.417e-06
600 REGULATION OF DNA REPLICATION 24 161 1.09e-06 8.452e-06
601 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 20 118 1.098e-06 8.504e-06
602 I KAPPAB KINASE NF KAPPAB SIGNALING 15 70 1.147e-06 8.863e-06
603 MAMMARY GLAND EPITHELIUM DEVELOPMENT 13 53 1.16e-06 8.921e-06
604 REGULATION OF NITRIC OXIDE BIOSYNTHETIC PROCESS 13 53 1.16e-06 8.921e-06
605 POSITIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 13 53 1.16e-06 8.921e-06
606 CELLULAR MODIFIED AMINO ACID METABOLIC PROCESS 29 220 1.194e-06 9.171e-06
607 POSITIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 24 162 1.221e-06 9.345e-06
608 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 24 162 1.221e-06 9.345e-06
609 CELL JUNCTION ORGANIZATION 26 185 1.248e-06 9.532e-06
610 POSITIVE REGULATION OF PROTEIN COMPLEX ASSEMBLY 27 197 1.29e-06 9.844e-06
611 MATERNAL PLACENTA DEVELOPMENT 10 31 1.306e-06 9.944e-06
612 POSITIVE REGULATION OF LEUKOCYTE MIGRATION 19 109 1.308e-06 9.944e-06
613 REGULATION OF PROTEIN COMPLEX ASSEMBLY 41 375 1.341e-06 1.018e-05
614 REGULATION OF LIGASE ACTIVITY 21 130 1.345e-06 1.02e-05
615 EPITHELIAL CELL DEVELOPMENT 26 186 1.384e-06 1.046e-05
616 MEIOTIC CELL CYCLE 26 186 1.384e-06 1.046e-05
617 NEGATIVE REGULATION OF DNA BINDING 12 46 1.47e-06 1.107e-05
618 REGULATION OF ALPHA BETA T CELL DIFFERENTIATION 12 46 1.47e-06 1.107e-05
619 CELLULAR RESPONSE TO REACTIVE NITROGEN SPECIES 8 19 1.494e-06 1.123e-05
620 POSITIVE REGULATION OF TRANSMEMBRANE TRANSPORT 21 131 1.53e-06 1.148e-05
621 SPINDLE CHECKPOINT 9 25 1.562e-06 1.168e-05
622 HISTONE PHOSPHORYLATION 9 25 1.562e-06 1.168e-05
623 POSITIVE REGULATION OF PROTEIN SECRETION 28 211 1.589e-06 1.186e-05
624 DNA GEOMETRIC CHANGE 16 81 1.611e-06 1.201e-05
625 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 20 121 1.652e-06 1.226e-05
626 REGULATION OF B CELL ACTIVATION 20 121 1.652e-06 1.226e-05
627 NEGATIVE REGULATION OF IMMUNE RESPONSE 20 121 1.652e-06 1.226e-05
628 PROTEIN TARGETING 43 406 1.734e-06 1.285e-05
629 NEGATIVE REGULATION OF INTRACELLULAR TRANSPORT 22 143 1.769e-06 1.308e-05
630 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO HYPOXIA 10 32 1.816e-06 1.341e-05
631 NEGATIVE REGULATION OF MUSCLE CELL DIFFERENTIATION 13 55 1.827e-06 1.345e-05
632 REGULATION OF B CELL PROLIFERATION 13 55 1.827e-06 1.345e-05
633 POSITIVE REGULATION OF OXIDOREDUCTASE ACTIVITY 12 47 1.887e-06 1.387e-05
634 INTEGRIN MEDIATED SIGNALING PATHWAY 16 82 1.911e-06 1.403e-05
635 REGULATION OF RESPONSE TO CYTOKINE STIMULUS 22 144 1.993e-06 1.46e-05
636 NEGATIVE REGULATION OF IMMUNE EFFECTOR PROCESS 18 102 2.056e-06 1.504e-05
637 PHAGOCYTOSIS 26 190 2.079e-06 1.519e-05
638 ENDOCRINE SYSTEM DEVELOPMENT 20 123 2.15e-06 1.568e-05
639 NEGATIVE REGULATION OF MAPK CASCADE 22 145 2.242e-06 1.633e-05
640 HAIR CYCLE 16 83 2.261e-06 1.642e-05
641 MOLTING CYCLE 16 83 2.261e-06 1.642e-05
642 CELL FATE COMMITMENT 29 227 2.272e-06 1.646e-05
643 REGULATION OF T HELPER CELL DIFFERENTIATION 9 26 2.285e-06 1.651e-05
644 ENDODERMAL CELL DIFFERENTIATION 11 40 2.283e-06 1.651e-05
645 CELLULAR COMPONENT MORPHOGENESIS 76 900 2.392e-06 1.725e-05
646 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 12 48 2.405e-06 1.729e-05
647 REGULATION OF NF KAPPAB IMPORT INTO NUCLEUS 12 48 2.405e-06 1.729e-05
648 REGULATION OF CHEMOKINE PRODUCTION 14 65 2.436e-06 1.749e-05
649 POSITIVE REGULATION OF INTERLEUKIN 12 PRODUCTION 10 33 2.492e-06 1.787e-05
650 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 21 135 2.519e-06 1.801e-05
651 T CELL RECEPTOR SIGNALING PATHWAY 22 146 2.52e-06 1.801e-05
652 REGULATION OF TRANSMEMBRANE TRANSPORT 44 426 2.568e-06 1.833e-05
653 VESICLE MEDIATED TRANSPORT 97 1239 2.723e-06 1.941e-05
654 SKELETAL SYSTEM DEVELOPMENT 46 455 2.735e-06 1.946e-05
655 REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS 25 181 2.739e-06 1.946e-05
656 CARTILAGE DEVELOPMENT 22 147 2.829e-06 2.007e-05
657 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL 15 75 2.882e-06 2.041e-05
658 REGULATION OF HAIR FOLLICLE DEVELOPMENT 7 15 3.001e-06 2.119e-05
659 CELLULAR RESPONSE TO NITRIC OXIDE 7 15 3.001e-06 2.119e-05
660 POSITIVE REGULATION OF CHEMOKINE PRODUCTION 12 49 3.044e-06 2.146e-05
661 REGULATION OF WOUND HEALING 20 126 3.157e-06 2.216e-05
662 OSTEOBLAST DIFFERENTIATION 20 126 3.157e-06 2.216e-05
663 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 20 126 3.157e-06 2.216e-05
664 CIRCADIAN RHYTHM 21 137 3.207e-06 2.247e-05
665 T CELL HOMEOSTASIS 10 34 3.376e-06 2.359e-05
666 NEGATIVE REGULATION OF MITOTIC NUCLEAR DIVISION 10 34 3.376e-06 2.359e-05
667 GLIAL CELL DEVELOPMENT 15 76 3.43e-06 2.393e-05
668 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 16 86 3.684e-06 2.562e-05
669 NEGATIVE REGULATION OF PEPTIDASE ACTIVITY 30 245 3.681e-06 2.562e-05
670 MYELOID LEUKOCYTE DIFFERENTIATION 17 96 3.74e-06 2.594e-05
671 POSITIVE REGULATION OF CYTOKINE SECRETION 17 96 3.74e-06 2.594e-05
672 POSITIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 31 258 3.79e-06 2.624e-05
673 ENDODERM FORMATION 12 50 3.828e-06 2.646e-05
674 PROTEASOMAL PROTEIN CATABOLIC PROCESS 32 271 3.857e-06 2.663e-05
675 STRIATED MUSCLE CELL DIFFERENTIATION 24 173 3.989e-06 2.75e-05
676 REGULATION OF SEQUESTERING OF CALCIUM ION 18 107 4.181e-06 2.878e-05
677 POSITIVE REGULATION OF RESPONSE TO WOUNDING 23 162 4.243e-06 2.915e-05
678 REGULATION OF GLIAL CELL DIFFERENTIATION 13 59 4.248e-06 2.915e-05
679 POSITIVE REGULATION OF CATION TRANSMEMBRANE TRANSPORT 17 97 4.331e-06 2.968e-05
680 NUCLEOBASE CONTAINING SMALL MOLECULE METABOLIC PROCESS 51 535 4.389e-06 3.003e-05
681 TUMOR NECROSIS FACTOR MEDIATED SIGNALING PATHWAY 19 118 4.455e-06 3.04e-05
682 MESODERM DEVELOPMENT 19 118 4.455e-06 3.04e-05
683 REGULATION OF REPRODUCTIVE PROCESS 20 129 4.574e-06 3.112e-05
684 NUCLEAR IMPORT 20 129 4.574e-06 3.112e-05
685 POSITIVE REGULATION OF RELEASE OF CYTOCHROME C FROM MITOCHONDRIA 9 28 4.622e-06 3.135e-05
686 NEGATIVE REGULATION OF CHROMOSOME SEGREGATION 9 28 4.622e-06 3.135e-05
687 ACTIN FILAMENT BASED PROCESS 45 450 4.672e-06 3.164e-05
688 REGULATION OF NEURON PROJECTION DEVELOPMENT 42 408 4.7e-06 3.179e-05
689 HUMORAL IMMUNE RESPONSE 25 187 4.961e-06 3.345e-05
690 MEIOTIC CELL CYCLE PROCESS 22 152 4.957e-06 3.345e-05
691 NEGATIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 16 88 5.033e-06 3.389e-05
692 POSITIVE REGULATION OF HAIR CYCLE 6 11 5.064e-06 3.405e-05
693 APOPTOTIC PROCESS INVOLVED IN MORPHOGENESIS 7 16 5.109e-06 3.431e-05
694 POSITIVE REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY 14 69 5.145e-06 3.45e-05
695 NEURON DEVELOPMENT 61 687 5.183e-06 3.47e-05
696 CELL SUBSTRATE ADHESION 23 164 5.235e-06 3.5e-05
697 REGULATION OF HAIR CYCLE 8 22 5.542e-06 3.689e-05
698 RELEASE OF CYTOCHROME C FROM MITOCHONDRIA 8 22 5.542e-06 3.689e-05
699 RESPONSE TO THYROID HORMONE 8 22 5.542e-06 3.689e-05
700 NEGATIVE REGULATION OF PROTEIN BINDING 15 79 5.674e-06 3.766e-05
701 ERBB SIGNALING PATHWAY 15 79 5.674e-06 3.766e-05
702 PLATELET ACTIVATION 21 142 5.732e-06 3.799e-05
703 MYELOID LEUKOCYTE MIGRATION 17 99 5.77e-06 3.819e-05
704 NEGATIVE REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 20 131 5.815e-06 3.844e-05
705 POSITIVE REGULATION OF GROWTH 29 238 5.86e-06 3.863e-05
706 REGULATION OF GENERATION OF PRECURSOR METABOLITES AND ENERGY 16 89 5.861e-06 3.863e-05
707 REGULATION OF ION HOMEOSTASIS 26 201 5.956e-06 3.92e-05
708 DNA DAMAGE RESPONSE DETECTION OF DNA DAMAGE 10 36 5.985e-06 3.933e-05
709 LEUKOCYTE MEDIATED IMMUNITY 25 189 6.007e-06 3.942e-05
710 REGULATION OF INTERLEUKIN 8 PRODUCTION 13 61 6.293e-06 4.118e-05
711 POSITIVE REGULATION OF STEM CELL PROLIFERATION 13 61 6.293e-06 4.118e-05
712 NEGATIVE REGULATION OF TUMOR NECROSIS FACTOR SUPERFAMILY CYTOKINE PRODUCTION 11 44 6.327e-06 4.135e-05
713 DNA REPLICATION INITIATION 9 29 6.412e-06 4.184e-05
714 REGULATION OF LYMPHOCYTE DIFFERENTIATION 20 132 6.544e-06 4.264e-05
715 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 17 100 6.639e-06 4.321e-05
716 DNA RECOMBINATION 27 215 6.945e-06 4.513e-05
717 EPIDERMIS DEVELOPMENT 30 253 7.053e-06 4.572e-05
718 GENERATION OF PRECURSOR METABOLITES AND ENERGY 33 292 7.055e-06 4.572e-05
719 POSITIVE REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 18 111 7.132e-06 4.615e-05
720 REGULATION OF JAK STAT CASCADE 21 144 7.168e-06 4.626e-05
721 REGULATION OF STAT CASCADE 21 144 7.168e-06 4.626e-05
722 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 25 191 7.25e-06 4.672e-05
723 NUCLEOSIDE TRIPHOSPHATE METABOLIC PROCESS 28 228 7.267e-06 4.677e-05
724 ENDODERM DEVELOPMENT 14 71 7.313e-06 4.7e-05
725 CELLULAR RESPONSE TO AMINO ACID STIMULUS 12 53 7.345e-06 4.714e-05
726 NEURON PROJECTION DEVELOPMENT 51 545 7.383e-06 4.732e-05
727 POSITIVE REGULATION OF LEUKOCYTE CHEMOTAXIS 15 81 7.822e-06 5.006e-05
728 ESTABLISHMENT OF PROTEIN LOCALIZATION TO ORGANELLE 38 361 7.912e-06 5.057e-05
729 RESPONSE TO INCREASED OXYGEN LEVELS 8 23 8.133e-06 5.177e-05
730 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO STRESS 8 23 8.133e-06 5.177e-05
731 RESPONSE TO HYPEROXIA 8 23 8.133e-06 5.177e-05
732 NEGATIVE REGULATION OF ANOIKIS 7 17 8.319e-06 5.281e-05
733 T CELL DIFFERENTIATION 19 123 8.308e-06 5.281e-05
734 PROTEIN LOCALIZATION TO MEMBRANE 39 376 8.54e-06 5.414e-05
735 RESPONSE TO AMPHETAMINE 9 30 8.764e-06 5.54e-05
736 RESPONSE TO X RAY 9 30 8.764e-06 5.54e-05
737 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 27 218 8.994e-06 5.678e-05
738 RESPONSE TO OSMOTIC STRESS 13 63 9.162e-06 5.776e-05
739 REGULATION OF VESICLE MEDIATED TRANSPORT 45 462 9.227e-06 5.802e-05
740 POSITIVE REGULATION OF INFLAMMATORY RESPONSE 18 113 9.217e-06 5.802e-05
741 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 20 135 9.25e-06 5.808e-05
742 CONNECTIVE TISSUE DEVELOPMENT 25 194 9.558e-06 5.994e-05
743 REGULATION OF VITAMIN METABOLIC PROCESS 6 12 9.707e-06 6.071e-05
744 PERK MEDIATED UNFOLDED PROTEIN RESPONSE 6 12 9.707e-06 6.071e-05
745 REGULATION OF CALCIUM ION IMPORT 17 103 9.995e-06 6.242e-05
746 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 11 46 1.006e-05 6.275e-05
747 RESPONSE TO TESTOSTERONE 10 38 1.018e-05 6.342e-05
748 POSITIVE REGULATION OF PROTEIN BINDING 14 73 1.025e-05 6.378e-05
749 REGULATION OF JNK CASCADE 22 159 1.038e-05 6.45e-05
750 HEMOSTASIS 34 311 1.055e-05 6.547e-05
751 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 12 55 1.104e-05 6.828e-05
752 EXECUTION PHASE OF APOPTOSIS 12 55 1.104e-05 6.828e-05
753 RESPONSE TO CAMP 17 104 1.141e-05 7.051e-05
754 NEGATIVE REGULATION OF MYOBLAST DIFFERENTIATION 8 24 1.168e-05 7.206e-05
755 RNA STABILIZATION 9 31 1.181e-05 7.281e-05
756 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 26 209 1.21e-05 7.45e-05
757 POSITIVE REGULATION OF GLIOGENESIS 11 47 1.256e-05 7.719e-05
758 MAINTENANCE OF LOCATION 20 138 1.293e-05 7.934e-05
759 REGULATION OF CELL MATURATION 7 18 1.304e-05 7.971e-05
760 POSITIVE REGULATION OF T HELPER CELL DIFFERENTIATION 7 18 1.304e-05 7.971e-05
761 LYMPHOCYTE APOPTOTIC PROCESS 7 18 1.304e-05 7.971e-05
762 ERBB2 SIGNALING PATHWAY 10 39 1.309e-05 7.975e-05
763 EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 10 39 1.309e-05 7.975e-05
764 NEGATIVE REGULATION OF MITOCHONDRION ORGANIZATION 10 39 1.309e-05 7.975e-05
765 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 18 116 1.338e-05 8.136e-05
766 FC GAMMA RECEPTOR SIGNALING PATHWAY 16 95 1.392e-05 8.431e-05
767 POSITIVE REGULATION OF T CELL PROLIFERATION 16 95 1.392e-05 8.431e-05
768 REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 16 95 1.392e-05 8.431e-05
769 MUSCLE TISSUE DEVELOPMENT 31 275 1.394e-05 8.437e-05
770 REGULATION OF DNA REPAIR 14 75 1.42e-05 8.545e-05
771 SECRETION 53 588 1.418e-05 8.545e-05
772 GRANULOCYTE MIGRATION 14 75 1.42e-05 8.545e-05
773 REGULATION OF VIRAL GENOME REPLICATION 14 75 1.42e-05 8.545e-05
774 TRANSITION METAL ION HOMEOSTASIS 17 106 1.479e-05 8.892e-05
775 MUSCLE CELL DEVELOPMENT 19 128 1.493e-05 8.967e-05
776 NEGATIVE REGULATION OF CYTOPLASMIC TRANSPORT 18 117 1.51e-05 9.041e-05
777 MAMMARY GLAND DEVELOPMENT 18 117 1.51e-05 9.041e-05
778 SECRETION BY CELL 46 486 1.54e-05 9.207e-05
779 VASCULAR PROCESS IN CIRCULATORY SYSTEM 22 163 1.549e-05 9.253e-05
780 RESPONSE TO AXON INJURY 11 48 1.558e-05 9.28e-05
781 NEGATIVE REGULATION OF COAGULATION 11 48 1.558e-05 9.28e-05
782 CELLULAR RESPONSE TO UV 13 66 1.562e-05 9.282e-05
783 MESODERM MORPHOGENESIS 13 66 1.562e-05 9.282e-05
784 NEGATIVE REGULATION OF T CELL DIFFERENTIATION 9 32 1.573e-05 9.334e-05
785 REGULATION OF LEUKOCYTE CHEMOTAXIS 16 96 1.595e-05 9.455e-05
786 CARDIAC MUSCLE TISSUE DEVELOPMENT 20 140 1.606e-05 9.506e-05
787 COGNITION 29 251 1.642e-05 9.694e-05
788 CELLULAR RESPONSE TO EPIDERMAL GROWTH FACTOR STIMULUS 8 25 1.644e-05 9.694e-05
789 NEGATIVE REGULATION OF CELL CYCLE G2 M PHASE TRANSITION 8 25 1.644e-05 9.694e-05
790 ENDOCRINE PANCREAS DEVELOPMENT 10 40 1.67e-05 9.835e-05
791 RESPONSE TO RETINOIC ACID 17 107 1.68e-05 9.88e-05
792 DEFENSE RESPONSE TO VIRUS 22 164 1.708e-05 0.0001003
793 CELLULAR AMINO ACID METABOLIC PROCESS 35 332 1.728e-05 0.0001012
794 REGULATION OF REGULATORY T CELL DIFFERENTIATION 6 13 1.728e-05 0.0001012
795 SUPEROXIDE ANION GENERATION 6 13 1.728e-05 0.0001012
796 SEXUAL REPRODUCTION 62 730 1.733e-05 0.0001013
797 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 13 67 1.852e-05 0.0001081
798 PALLIUM DEVELOPMENT 21 153 1.855e-05 0.0001081
799 REGULATION OF DNA RECOMBINATION 12 58 1.959e-05 0.000114
800 POSITIVE REGULATION OF CYTOKINE BIOSYNTHETIC PROCESS 12 58 1.959e-05 0.000114
801 REGULATION OF TRANSLATION IN RESPONSE TO STRESS 7 19 1.977e-05 0.000114
802 MITOTIC G2 M TRANSITION CHECKPOINT 7 19 1.977e-05 0.000114
803 REGULATION OF HYDROGEN PEROXIDE INDUCED CELL DEATH 7 19 1.977e-05 0.000114
804 REGULATION OF NITRIC OXIDE SYNTHASE BIOSYNTHETIC PROCESS 7 19 1.977e-05 0.000114
805 RESPONSE TO SALT STRESS 7 19 1.977e-05 0.000114
806 NUCLEOPHAGY 7 19 1.977e-05 0.000114
807 REGULATION OF INTERFERON ALPHA PRODUCTION 7 19 1.977e-05 0.000114
808 SUPEROXIDE METABOLIC PROCESS 9 33 2.069e-05 0.000119
809 G2 DNA DAMAGE CHECKPOINT 9 33 2.069e-05 0.000119
810 MITOTIC RECOMBINATION 10 41 2.112e-05 0.0001213
811 POSITIVE REGULATION OF CHEMOTAXIS 18 120 2.151e-05 0.0001234
812 REGULATION OF TYROSINE PHOSPHORYLATION OF STAT PROTEIN 13 68 2.188e-05 0.0001254
813 CELL CELL SIGNALING 64 767 2.195e-05 0.0001256
814 POSITIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 15 88 2.213e-05 0.0001265
815 PROTEIN IMPORT 21 155 2.264e-05 0.0001293
816 DEVELOPMENTAL PROGRAMMED CELL DEATH 8 26 2.273e-05 0.0001296
817 B CELL ACTIVATION 19 132 2.33e-05 0.0001325
818 POSITIVE REGULATION OF CELL DIVISION 19 132 2.33e-05 0.0001325
819 REGULATION OF CELL CYCLE G2 M PHASE TRANSITION 12 59 2.351e-05 0.0001336
820 REGULATION OF PROTEIN KINASE B SIGNALING 18 121 2.413e-05 0.0001369
821 POSITIVE REGULATION OF LIGASE ACTIVITY 17 110 2.434e-05 0.0001379
822 REGULATION OF CHEMOTAXIS 23 180 2.461e-05 0.0001393
823 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 42 437 2.497e-05 0.0001412
824 PURINE CONTAINING COMPOUND METABOLIC PROCESS 39 394 2.501e-05 0.0001412
825 CIRCULATORY SYSTEM PROCESS 37 366 2.541e-05 0.0001433
826 EPITHELIAL CELL PROLIFERATION 15 89 2.543e-05 0.0001433
827 REGULATION OF MITOPHAGY 10 42 2.652e-05 0.0001492
828 POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 9 34 2.692e-05 0.0001506
829 ER NUCLEUS SIGNALING PATHWAY 9 34 2.692e-05 0.0001506
830 PROTEIN KINASE B SIGNALING 9 34 2.692e-05 0.0001506
831 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 9 34 2.692e-05 0.0001506
832 CELLULAR RESPONSE TO ALKALOID 9 34 2.692e-05 0.0001506
833 NEGATIVE REGULATION OF INFLAMMATORY RESPONSE 16 100 2.699e-05 0.0001508
834 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 18 122 2.703e-05 0.0001508
835 CELLULAR AMIDE METABOLIC PROCESS 61 727 2.902e-05 0.0001615
836 T CELL MIGRATION 6 14 2.898e-05 0.0001615
837 ENDOPLASMIC RETICULUM CALCIUM ION HOMEOSTASIS 7 20 2.913e-05 0.0001618
838 PROTEIN REFOLDING 7 20 2.913e-05 0.0001618
839 NEGATIVE REGULATION OF PROTEIN COMPLEX DISASSEMBLY 22 170 3.01e-05 0.0001669
840 INTERFERON GAMMA MEDIATED SIGNALING PATHWAY 13 70 3.025e-05 0.0001673
841 PROTEIN LOCALIZATION TO MITOCHONDRION 13 70 3.025e-05 0.0001673
842 POSITIVE REGULATION OF LYMPHOCYTE DIFFERENTIATION 14 80 3.041e-05 0.0001681
843 REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 16 101 3.063e-05 0.0001691
844 ION HOMEOSTASIS 51 576 3.294e-05 0.0001816
845 CELLULAR RESPONSE TO HYDROGEN PEROXIDE 12 61 3.343e-05 0.0001839
846 GLUTATHIONE METABOLIC PROCESS 12 61 3.343e-05 0.0001839
847 REGULATION OF RESPONSE TO REACTIVE OXYGEN SPECIES 9 35 3.468e-05 0.0001905
848 NEGATIVE REGULATION OF T CELL PROLIFERATION 11 52 3.48e-05 0.000191
849 POSITIVE REGULATION OF PROTEIN KINASE B SIGNALING 14 81 3.513e-05 0.0001926
850 SKIN EPIDERMIS DEVELOPMENT 13 71 3.539e-05 0.0001937
851 REGULATION OF CELL SIZE 22 172 3.611e-05 0.0001972
852 POSITIVE REGULATION OF ERK1 AND ERK2 CASCADE 22 172 3.611e-05 0.0001972
853 REGULATION OF HORMONE SECRETION 29 262 3.667e-05 2e-04
854 REGULATION OF DEVELOPMENTAL GROWTH 31 289 3.688e-05 0.0002009
855 NEGATIVE REGULATION OF GROWTH 27 236 3.78e-05 0.0002057
856 REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY 17 114 3.901e-05 0.000212
857 SINGLE ORGANISM BIOSYNTHETIC PROCESS 98 1340 3.924e-05 0.0002129
858 STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 16 103 3.925e-05 0.0002129
859 REGULATION OF TISSUE REMODELING 12 62 3.963e-05 0.0002147
860 CHEMOKINE MEDIATED SIGNALING PATHWAY 13 72 4.127e-05 0.0002233
861 RESPONSE TO COPPER ION 8 28 4.144e-05 0.0002237
862 RESPONSE TO GONADOTROPIN 8 28 4.144e-05 0.0002237
863 APOPTOTIC PROCESS INVOLVED IN DEVELOPMENT 7 21 4.186e-05 0.0002252
864 MRNA TRANSCRIPTION 7 21 4.186e-05 0.0002252
865 RESPONSE TO NITRIC OXIDE 7 21 4.186e-05 0.0002252
866 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 11 53 4.199e-05 0.0002254
867 INTRINSIC APOPTOTIC SIGNALING PATHWAY BY P53 CLASS MEDIATOR 11 53 4.199e-05 0.0002254
868 PROTEIN OLIGOMERIZATION 41 434 4.602e-05 0.0002467
869 RESPONSE TO MURAMYL DIPEPTIDE 6 15 4.631e-05 0.0002468
870 RESPIRATORY BURST 6 15 4.631e-05 0.0002468
871 NEGATIVE REGULATION OF INTERLEUKIN 8 PRODUCTION 6 15 4.631e-05 0.0002468
872 POSITIVE REGULATION OF NUCLEASE ACTIVITY 6 15 4.631e-05 0.0002468
873 NEGATIVE REGULATION OF CD4 POSITIVE ALPHA BETA T CELL ACTIVATION 6 15 4.631e-05 0.0002468
874 NEGATIVE REGULATION OF SECRETION 24 200 4.669e-05 0.0002486
875 REGULATION OF CELL KILLING 12 63 4.68e-05 0.0002488
876 REGULATION OF ORGAN GROWTH 13 73 4.799e-05 0.0002549
877 REGULATION OF RNA STABILITY 19 139 4.84e-05 0.0002568
878 ODONTOGENESIS 16 105 4.995e-05 0.0002647
879 POSITIVE REGULATION OF CALCIUM ION IMPORT 11 54 5.043e-05 0.0002669
880 SISTER CHROMATID SEGREGATION 22 176 5.143e-05 0.0002719
881 CELLULAR RESPONSE TO STARVATION 17 117 5.469e-05 0.0002887
882 POSITIVE REGULATION OF MONOOXYGENASE ACTIVITY 8 29 5.478e-05 0.0002887
883 POSITIVE REGULATION OF INTERLEUKIN 10 PRODUCTION 8 29 5.478e-05 0.0002887
884 DNA SYNTHESIS INVOLVED IN DNA REPAIR 13 74 5.564e-05 0.0002929
885 POSITIVE REGULATION OF CALCIUM ION TRANSPORT 16 106 5.619e-05 0.0002955
886 REGULATION OF PROTEIN HOMODIMERIZATION ACTIVITY 7 22 5.881e-05 0.0003079
887 REGULATION OF WNT SIGNALING PATHWAY 32 310 5.882e-05 0.0003079
888 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC SIGNALING PATHWAY 7 22 5.881e-05 0.0003079
889 REGULATION OF T HELPER 1 TYPE IMMUNE RESPONSE 7 22 5.881e-05 0.0003079
890 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 25 216 5.976e-05 0.0003124
891 ESTABLISHMENT OF PROTEIN LOCALIZATION 102 1423 5.988e-05 0.0003127
892 EPHRIN RECEPTOR SIGNALING PATHWAY 14 85 6.105e-05 0.0003185
893 RESPONSE TO COCAINE 10 46 6.149e-05 0.0003193
894 CELLULAR IRON ION HOMEOSTASIS 10 46 6.149e-05 0.0003193
895 POSITIVE REGULATION OF PHAGOCYTOSIS 10 46 6.149e-05 0.0003193
896 NEGATIVE REGULATION OF CYTOKINE SECRETION 10 46 6.149e-05 0.0003193
897 CELLULAR RESPONSE TO RETINOIC ACID 12 65 6.455e-05 0.0003341
898 REGULATION OF PROTEIN COMPLEX DISASSEMBLY 25 217 6.447e-05 0.0003341
899 PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 12 65 6.455e-05 0.0003341
900 ADAPTIVE IMMUNE RESPONSE BASED ON SOMATIC RECOMBINATION OF IMMUNE RECEPTORS BUILT FROM IMMUNOGLOBULIN SUPERFAMILY DOMAINS 20 154 6.479e-05 0.0003346
901 RESPONSE TO STARVATION 20 154 6.479e-05 0.0003346
902 EPIDERMAL CELL DIFFERENTIATION 19 142 6.507e-05 0.0003357
903 POSITIVE REGULATION OF B CELL ACTIVATION 14 86 6.968e-05 0.0003591
904 REGULATION OF ANATOMICAL STRUCTURE SIZE 43 472 7.053e-05 0.000363
905 POSITIVE REGULATION OF INTERFERON ALPHA PRODUCTION 6 16 7.102e-05 0.0003652
906 RESPONSE TO EPIDERMAL GROWTH FACTOR 8 30 7.151e-05 0.000366
907 POSITIVE REGULATION OF INTERFERON BETA PRODUCTION 8 30 7.151e-05 0.000366
908 DNA STRAND ELONGATION 8 30 7.151e-05 0.000366
909 HYDROGEN PEROXIDE METABOLIC PROCESS 8 30 7.151e-05 0.000366
910 CHROMOSOME SEGREGATION 29 272 7.244e-05 0.0003704
911 POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS 10 47 7.471e-05 0.0003812
912 CHAPERONE MEDIATED PROTEIN FOLDING 10 47 7.471e-05 0.0003812
913 NEURAL NUCLEUS DEVELOPMENT 12 66 7.543e-05 0.0003841
914 RESPONSE TO CARBOHYDRATE 21 168 7.553e-05 0.0003841
915 INTRACELLULAR RECEPTOR SIGNALING PATHWAY 21 168 7.553e-05 0.0003841
916 CYTOKINE PRODUCTION 17 120 7.569e-05 0.0003845
917 GAMETE GENERATION 51 595 7.596e-05 0.0003854
918 PROTEIN LOCALIZATION TO NUCLEUS 20 156 7.781e-05 0.0003944
919 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 19 144 7.884e-05 0.0003992
920 TISSUE REMODELING 14 87 7.936e-05 0.0004014
921 REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 11 57 8.499e-05 0.0004294
922 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 18 133 8.644e-05 0.0004362
923 POSITIVE REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL 9 39 8.726e-05 0.0004389
924 ASTROCYTE DIFFERENTIATION 9 39 8.726e-05 0.0004389
925 EMBRYO IMPLANTATION 9 39 8.726e-05 0.0004389
926 MEIOSIS I 14 88 9.019e-05 0.0004531
927 REGULATION OF MYOBLAST DIFFERENTIATION 10 48 9.027e-05 0.0004531
928 RESPONSE TO INTERLEUKIN 4 8 31 9.227e-05 0.0004622
929 HOMEOSTASIS OF NUMBER OF CELLS WITHIN A TISSUE 8 31 9.227e-05 0.0004622
930 REGULATION OF MYELOID CELL DIFFERENTIATION 22 183 9.265e-05 0.0004635
931 REGULATION OF PEPTIDE SECRETION 24 209 9.431e-05 0.0004713
932 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 26 236 9.829e-05 0.0004907
933 REGULATION OF T HELPER 2 CELL DIFFERENTIATION 5 11 0.0001004 0.0004989
934 NEGATIVE REGULATION OF WOUND HEALING 11 58 0.0001003 0.0004989
935 REGULATION OF INTERLEUKIN 1 PRODUCTION 11 58 0.0001003 0.0004989
936 REGULATION OF CHRONIC INFLAMMATORY RESPONSE 5 11 0.0001004 0.0004989
937 RESPIRATORY SYSTEM DEVELOPMENT 23 197 0.0001017 0.0005052
938 REGULATION OF PHAGOCYTOSIS 12 68 0.000102 0.0005053
939 POSITIVE REGULATION OF CELL CYCLE PHASE TRANSITION 12 68 0.000102 0.0005053
940 LYMPHOCYTE MEDIATED IMMUNITY 19 147 0.0001043 0.0005165
941 NEGATIVE REGULATION OF RELEASE OF CYTOCHROME C FROM MITOCHONDRIA 6 17 0.0001052 0.0005192
942 REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 6 17 0.0001052 0.0005192
943 RESPONSE TO MANGANESE ION 6 17 0.0001052 0.0005192
944 REGULATION OF ACTIVATED T CELL PROLIFERATION 9 40 0.0001077 0.0005305
945 NEGATIVE REGULATION OF LYMPHOCYTE DIFFERENTIATION 9 40 0.0001077 0.0005305
946 REGULATION OF STEROID BIOSYNTHETIC PROCESS 10 49 0.0001085 0.0005331
947 LYMPHOCYTE MIGRATION 10 49 0.0001085 0.0005331
948 REGULATION OF NUCLEOTIDE METABOLIC PROCESS 24 211 0.0001095 0.0005374
949 REGULATION OF LEUKOCYTE APOPTOTIC PROCESS 13 79 0.0001119 0.0005489
950 POSITIVE REGULATION OF CELL GROWTH 19 148 0.0001143 0.0005599
951 NEGATIVE REGULATION OF HOMEOSTATIC PROCESS 17 124 0.0001145 0.0005605
952 POSITIVE REGULATION OF GLIAL CELL DIFFERENTIATION 8 32 0.0001178 0.0005755
953 HEART MORPHOGENESIS 24 212 0.0001179 0.0005755
954 REGULATION OF ENDOCYTOSIS 23 199 0.0001186 0.0005786
955 SEX DIFFERENTIATION 28 266 0.0001194 0.0005818
956 SENSORY ORGAN MORPHOGENESIS 26 239 0.000121 0.0005887
957 OVULATION CYCLE 16 113 0.0001227 0.0005966
958 RESPONSE TO PROGESTERONE 10 50 0.0001297 0.0006301
959 CELLULAR RESPONSE TO LIGHT STIMULUS 14 91 0.0001307 0.000633
960 MITOTIC SISTER CHROMATID SEGREGATION 14 91 0.0001307 0.000633
961 ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE ANTIGEN VIA MHC CLASS I 14 91 0.0001307 0.000633
962 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 9 41 0.0001321 0.0006363
963 MITOTIC SPINDLE ASSEMBLY 9 41 0.0001321 0.0006363
964 NEGATIVE REGULATION OF STRESS ACTIVATED MAPK CASCADE 9 41 0.0001321 0.0006363
965 MICROTUBULE CYTOSKELETON ORGANIZATION INVOLVED IN MITOSIS 9 41 0.0001321 0.0006363
966 NEGATIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 9 41 0.0001321 0.0006363
967 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 11 60 0.0001381 0.0006643
968 REGULATION OF PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 15 103 0.0001437 0.0006909
969 DNA STRAND ELONGATION INVOLVED IN DNA REPLICATION 7 25 0.0001457 0.0006975
970 POSITIVE REGULATION OF MYELOID CELL DIFFERENTIATION 13 81 0.0001455 0.0006975
971 REGULATION OF JUN KINASE ACTIVITY 13 81 0.0001455 0.0006975
972 PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 7 25 0.0001457 0.0006975
973 SOMATIC CELL DNA RECOMBINATION 8 33 0.0001489 0.0007097
974 SOMATIC DIVERSIFICATION OF IMMUNE RECEPTORS VIA GERMLINE RECOMBINATION WITHIN A SINGLE LOCUS 8 33 0.0001489 0.0007097
975 RESPONSE TO VITAMIN D 8 33 0.0001489 0.0007097
976 REGULATION OF CELL AGING 8 33 0.0001489 0.0007097
977 NEGATIVE REGULATION OF RESPONSE TO REACTIVE OXYGEN SPECIES 6 18 0.0001513 0.0007192
978 CELL DEATH IN RESPONSE TO OXIDATIVE STRESS 6 18 0.0001513 0.0007192
979 RESPONSE TO PLATELET DERIVED GROWTH FACTOR 6 18 0.0001513 0.0007192
980 CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE 18 139 0.0001533 0.0007281
981 NUCLEAR TRANSPORT 34 355 0.0001536 0.0007285
982 ORGANOPHOSPHATE METABOLIC PROCESS 68 885 0.0001541 0.00073
983 CELLULAR RESPONSE TO FATTY ACID 10 51 0.0001544 0.00073
984 NEGATIVE REGULATION OF ION TRANSPORT 17 127 0.0001542 0.00073
985 POSITIVE REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 9 42 0.0001609 0.0007589
986 REGULATION OF NIK NF KAPPAB SIGNALING 9 42 0.0001609 0.0007589
987 STEM CELL DIFFERENTIATION 22 190 0.000161 0.0007589
988 REGULATION OF CHROMATIN ORGANIZATION 19 152 0.0001632 0.0007685
989 REGULATION OF INTERLEUKIN 10 SECRETION 5 12 0.0001651 0.0007735
990 UV PROTECTION 5 12 0.0001651 0.0007735
991 NEGATIVE REGULATION OF CD4 POSITIVE ALPHA BETA T CELL DIFFERENTIATION 5 12 0.0001651 0.0007735
992 NEGATIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 13 82 0.0001652 0.0007735
993 POSITIVE REGULATION OF EXECUTION PHASE OF APOPTOSIS 5 12 0.0001651 0.0007735
994 POSITIVE REGULATION OF CAMP MEDIATED SIGNALING 5 12 0.0001651 0.0007735
995 FEMALE SEX DIFFERENTIATION 16 116 0.0001677 0.0007843
996 ENERGY DERIVATION BY OXIDATION OF ORGANIC COMPOUNDS 24 217 0.0001689 0.0007893
997 REGULATION OF LIPID BIOSYNTHETIC PROCESS 17 128 0.0001699 0.000793
998 REGULATION OF MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION 21 178 0.000173 0.0008065
999 DIVALENT INORGANIC CATION HOMEOSTASIS 33 343 0.0001754 0.000817
1000 POSITIVE REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 10 52 0.0001828 0.0008499
1001 CELLULAR RESPONSE TO IONIZING RADIATION 10 52 0.0001828 0.0008499
1002 REGULATION OF EPITHELIAL CELL MIGRATION 20 166 0.0001842 0.0008552
1003 RESPONSE TO INSULIN 23 205 0.0001852 0.0008593
1004 ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE OR POLYSACCHARIDE ANTIGEN VIA MHC CLASS II 14 94 0.0001862 0.0008611
1005 ELECTRON TRANSPORT CHAIN 14 94 0.0001862 0.0008611
1006 ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE ANTIGEN VIA MHC CLASS II 14 94 0.0001862 0.0008611
1007 REGULATION OF HORMONE LEVELS 42 478 0.0001883 0.0008701
1008 CELLULAR RESPONSE TO INTERLEUKIN 4 7 26 0.000191 0.00088
1009 VASODILATION 7 26 0.000191 0.00088
1010 POSITIVE REGULATION OF TISSUE REMODELING 7 26 0.000191 0.00088
1011 PEPTIDE METABOLIC PROCESS 48 571 0.0001936 0.0008908
1012 CELL CYCLE ARREST 19 154 0.0001939 0.0008914
1013 REGULATION OF FAT CELL DIFFERENTIATION 15 106 0.0001992 0.0009148
1014 NEGATIVE REGULATION OF MAP KINASE ACTIVITY 12 73 0.0002057 0.0009392
1015 POSITIVE REGULATION OF STAT CASCADE 12 73 0.0002057 0.0009392
1016 PANCREAS DEVELOPMENT 12 73 0.0002057 0.0009392
1017 CELLULAR RESPONSE TO KETONE 12 73 0.0002057 0.0009392
1018 POSITIVE REGULATION OF JAK STAT CASCADE 12 73 0.0002057 0.0009392
1019 REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 12 73 0.0002057 0.0009392
1020 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 14 95 0.0002087 0.000952
1021 CELLULAR RESPONSE TO GAMMA RADIATION 6 19 0.000212 0.0009635
1022 OXIDATIVE PHOSPHORYLATION 13 84 0.0002118 0.0009635
1023 TISSUE MIGRATION 13 84 0.0002118 0.0009635
1024 X DE NOVO PROTEIN FOLDING 6 19 0.000212 0.0009635
1025 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 10 53 0.0002156 0.0009787
1026 REGULATION OF AXONOGENESIS 20 168 0.0002166 0.0009823
1027 CELL MATRIX ADHESION 16 119 0.0002265 0.001026
1028 RESPONSE TO MINERALOCORTICOID 8 35 0.0002313 0.001047
1029 CARDIOCYTE DIFFERENTIATION 14 96 0.0002335 0.001056
1030 REGULATION OF INTERFERON BETA PRODUCTION 9 44 0.0002343 0.001056
1031 CELLULAR RESPONSE TO CARBOHYDRATE STIMULUS 12 74 0.0002347 0.001056
1032 CARDIAC MUSCLE CELL DIFFERENTIATION 12 74 0.0002347 0.001056
1033 INTERSTRAND CROSS LINK REPAIR 9 44 0.0002343 0.001056
1034 REGULATION OF TYROSINE PHOSPHORYLATION OF STAT3 PROTEIN 9 44 0.0002343 0.001056
1035 MUSCLE ORGAN DEVELOPMENT 28 277 0.0002364 0.001063
1036 REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 15 108 0.0002456 0.001103
1037 INFLAMMATORY RESPONSE TO ANTIGENIC STIMULUS 7 27 0.000247 0.001108
1038 NEGATIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 11 64 0.0002506 0.001123
1039 ESTABLISHMENT OF PROTEIN LOCALIZATION TO MEMBRANE 27 264 0.0002511 0.001124
1040 REGULATION OF LYMPHOCYTE APOPTOTIC PROCESS 10 54 0.0002531 0.00113
1041 ALPHA BETA T CELL ACTIVATION 10 54 0.0002531 0.00113
1042 B CELL RECEPTOR SIGNALING PATHWAY 10 54 0.0002531 0.00113
1043 NEGATIVE REGULATION OF CELL GROWTH 20 170 0.0002539 0.001131
1044 GLUCOSE HOMEOSTASIS 20 170 0.0002539 0.001131
1045 CARBOHYDRATE HOMEOSTASIS 20 170 0.0002539 0.001131
1046 VASCULAR SMOOTH MUSCLE CELL DIFFERENTIATION 5 13 0.0002575 0.001141
1047 CELLULAR RESPONSE TO HEPATOCYTE GROWTH FACTOR STIMULUS 5 13 0.0002575 0.001141
1048 MITOTIC G2 DNA DAMAGE CHECKPOINT 5 13 0.0002575 0.001141
1049 RESPONSE TO HEPATOCYTE GROWTH FACTOR 5 13 0.0002575 0.001141
1050 VENTRICULAR CARDIAC MUSCLE CELL DEVELOPMENT 5 13 0.0002575 0.001141
1051 REGULATION OF RESPONSE TO BIOTIC STIMULUS 25 237 0.0002618 0.001159
1052 EMBRYONIC ORGAN MORPHOGENESIS 28 279 0.0002662 0.001177
1053 CELLULAR GLUCOSE HOMEOSTASIS 12 75 0.0002672 0.00118
1054 ODONTOGENESIS OF DENTIN CONTAINING TOOTH 12 75 0.0002672 0.00118
1055 REGULATION OF RESPONSE TO EXTRACELLULAR STIMULUS 20 171 0.0002747 0.00121
1056 REGULATION OF RESPONSE TO NUTRIENT LEVELS 20 171 0.0002747 0.00121
1057 ORGANIC ACID METABOLIC PROCESS 71 953 0.0002751 0.001211
1058 ALPHA BETA T CELL DIFFERENTIATION 9 45 0.0002803 0.001232
1059 REGULATION OF ALCOHOL BIOSYNTHETIC PROCESS 9 45 0.0002803 0.001232
1060 REGULATION OF ERYTHROCYTE DIFFERENTIATION 8 36 0.0002848 0.00125
1061 HYDROGEN PEROXIDE CATABOLIC PROCESS 6 20 0.0002904 0.001269
1062 RESPONSE TO PROTOZOAN 6 20 0.0002904 0.001269
1063 RESPONSE TO VITAMIN A 6 20 0.0002904 0.001269
1064 BRANCHING INVOLVED IN MAMMARY GLAND DUCT MORPHOGENESIS 6 20 0.0002904 0.001269
1065 RESPONSE TO LEAD ION 6 20 0.0002904 0.001269
1066 EPIDERMAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 10 55 0.000296 0.001292
1067 MACROAUTOPHAGY 28 281 0.0002993 0.001305
1068 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 34 368 0.0003015 0.001314
1069 MAMMARY GLAND DUCT MORPHOGENESIS 7 28 0.0003156 0.001374
1070 ANTIGEN PROCESSING AND PRESENTATION OF EXOGENOUS PEPTIDE ANTIGEN VIA MHC CLASS I 11 66 0.0003311 0.00144
1071 LEUKOCYTE PROLIFERATION 13 88 0.0003394 0.001474
1072 REGULATION OF SYSTEM PROCESS 43 507 0.0003398 0.001475
1073 DETOXIFICATION 12 77 0.0003436 0.00149
1074 EPITHELIAL TO MESENCHYMAL TRANSITION 10 56 0.0003448 0.001494
1075 ACTIN FILAMENT ORGANIZATION 20 174 0.0003459 0.001497
1076 POSITIVE REGULATION OF B CELL PROLIFERATION 8 37 0.0003479 0.001503
1077 REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION 8 37 0.0003479 0.001503
1078 NUCLEAR CHROMOSOME SEGREGATION 24 228 0.0003553 0.001533
1079 NEURON PROJECTION MORPHOGENESIS 36 402 0.0003695 0.001593
1080 UROGENITAL SYSTEM DEVELOPMENT 29 299 0.00037 0.001594
1081 ALPHA AMINO ACID METABOLIC PROCESS 24 229 0.0003789 0.001631
1082 B CELL DIFFERENTIATION 13 89 0.0003799 0.001634
1083 REGULATION OF PODOSOME ASSEMBLY 5 14 0.0003844 0.001644
1084 POSITIVE REGULATION OF NITRIC OXIDE SYNTHASE BIOSYNTHETIC PROCESS 5 14 0.0003844 0.001644
1085 REGULATION OF SPINDLE CHECKPOINT 5 14 0.0003844 0.001644
1086 POSITIVE REGULATION OF CELL SIZE 5 14 0.0003844 0.001644
1087 NEGATIVE REGULATION OF MYELOID CELL APOPTOTIC PROCESS 5 14 0.0003844 0.001644
1088 POST EMBRYONIC ORGAN DEVELOPMENT 5 14 0.0003844 0.001644
1089 NECROPTOTIC PROCESS 6 21 0.0003899 0.001663
1090 VIRAL GENOME REPLICATION 6 21 0.0003899 0.001663
1091 SOMATIC RECOMBINATION OF IMMUNOGLOBULIN GENE SEGMENTS 6 21 0.0003899 0.001663
1092 REGULATION OF IMMUNOGLOBULIN PRODUCTION 9 47 0.0003948 0.001682
1093 POSITIVE REGULATION OF EPITHELIAL CELL DIFFERENTIATION 10 57 4e-04 0.001691
1094 REGULATION OF CELL CYCLE CHECKPOINT 7 29 0.0003986 0.001691
1095 CIRCADIAN REGULATION OF GENE EXPRESSION 10 57 4e-04 0.001691
1096 ENDOTHELIAL CELL MIGRATION 10 57 4e-04 0.001691
1097 REGULATION OF HEART MORPHOGENESIS 7 29 0.0003986 0.001691
1098 POSITIVE REGULATION OF NIK NF KAPPAB SIGNALING 7 29 0.0003986 0.001691
1099 KERATINOCYTE DIFFERENTIATION 14 101 0.0003992 0.001691
1100 RESPONSE TO ISCHEMIA 7 29 0.0003986 0.001691
1101 CAMERA TYPE EYE MORPHOGENESIS 14 101 0.0003992 0.001691
1102 REGULATION OF DOUBLE STRAND BREAK REPAIR 8 38 0.000422 0.001777
1103 COLLAGEN FIBRIL ORGANIZATION 8 38 0.000422 0.001777
1104 LYMPHOCYTE CHEMOTAXIS 8 38 0.000422 0.001777
1105 POSITIVE REGULATION OF ORGAN GROWTH 8 38 0.000422 0.001777
1106 MESENCHYME DEVELOPMENT 21 190 0.0004244 0.001785
1107 RESPONSE TO TYPE I INTERFERON 11 68 0.0004323 0.001812
1108 MULTICELLULAR ORGANISMAL RESPONSE TO STRESS 11 68 0.0004323 0.001812
1109 NEGATIVE REGULATION OF MULTI ORGANISM PROCESS 18 151 0.0004321 0.001812
1110 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 11 68 0.0004323 0.001812
1111 POSITIVE REGULATION OF ENDOCYTOSIS 15 114 0.0004452 0.001865
1112 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 29 303 0.0004603 0.001926
1113 CELLULAR RESPONSE TO CORTICOSTEROID STIMULUS 10 58 0.0004625 0.001933
1114 IMMUNOGLOBULIN PRODUCTION 9 48 0.0004651 0.001941
1115 REGULATION OF INTERLEUKIN 2 PRODUCTION 9 48 0.0004651 0.001941
1116 DOUBLE STRAND BREAK REPAIR 19 165 0.0004703 0.001961
1117 MICROTUBULE CYTOSKELETON ORGANIZATION 32 348 0.0004861 0.002025
1118 PROTEIN SUMOYLATION 15 115 0.0004893 0.002034
1119 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 14 103 0.0004892 0.002034
1120 IRON ION HOMEOSTASIS 11 69 0.000492 0.002042
1121 RESPONSE TO ACTIVITY 11 69 0.000492 0.002042
1122 REGULATION OF CENTROSOME CYCLE 8 39 0.0005084 0.002101
1123 CELLULAR RESPONSE TO NUTRIENT 8 39 0.0005084 0.002101
1124 NUCLEOTIDE EXCISION REPAIR DNA INCISION 8 39 0.0005084 0.002101
1125 PEPTIDYL TYROSINE AUTOPHOSPHORYLATION 8 39 0.0005084 0.002101
1126 PLATELET AGGREGATION 8 39 0.0005084 0.002101
1127 REGULATION OF INTERLEUKIN 17 PRODUCTION 6 22 0.000514 0.002118
1128 REGULATION OF CELLULAR RESPIRATION 6 22 0.000514 0.002118
1129 REGULATION OF RESPONSE TO INTERFERON GAMMA 6 22 0.000514 0.002118
1130 NEGATIVE REGULATION OF HEMOPOIESIS 16 128 0.0005215 0.002147
1131 POSITIVE REGULATION OF VIRAL PROCESS 13 92 0.0005271 0.002169
1132 POSITIVE REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 10 59 0.0005328 0.00219
1133 REGULATION OF TOLL LIKE RECEPTOR SIGNALING PATHWAY 9 49 0.0005453 0.002238
1134 REGULATION OF NITRIC OXIDE SYNTHASE ACTIVITY 9 49 0.0005453 0.002238
1135 NEGATIVE REGULATION OF CYTOSKELETON ORGANIZATION 23 221 0.0005482 0.002247
1136 POSITIVE REGULATION OF RESPONSE TO OXIDATIVE STRESS 5 15 0.0005535 0.002251
1137 POSITIVE REGULATION OF T HELPER 1 TYPE IMMUNE RESPONSE 5 15 0.0005535 0.002251
1138 DNA REPLICATION CHECKPOINT 5 15 0.0005535 0.002251
1139 NEGATIVE REGULATION OF B CELL PROLIFERATION 5 15 0.0005535 0.002251
1140 NEGATIVE REGULATION OF ALPHA BETA T CELL DIFFERENTIATION 5 15 0.0005535 0.002251
1141 NEUROTROPHIN TRK RECEPTOR SIGNALING PATHWAY 5 15 0.0005535 0.002251
1142 T CELL APOPTOTIC PROCESS 5 15 0.0005535 0.002251
1143 CELLULAR RESPONSE TO GONADOTROPIN STIMULUS 5 15 0.0005535 0.002251
1144 MRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 5 15 0.0005535 0.002251
1145 SPINDLE ASSEMBLY 11 70 0.0005583 0.002269
1146 CELL JUNCTION ASSEMBLY 16 129 0.0005689 0.00231
1147 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 15 117 0.0005887 0.002388
1148 REGULATION OF CYCLIC NUCLEOTIDE METABOLIC PROCESS 18 155 0.0005926 0.0024
1149 REGULATION OF CELL PROJECTION ASSEMBLY 18 155 0.0005926 0.0024
1150 MAMMARY GLAND MORPHOGENESIS 8 40 0.0006085 0.00246
1151 CYTOPLASMIC SEQUESTERING OF PROTEIN 8 40 0.0006085 0.00246
1152 CELLULAR DEFENSE RESPONSE 10 60 0.0006117 0.002471
1153 REGULATION OF INTERLEUKIN 4 PRODUCTION 7 31 0.0006165 0.002488
1154 REGULATION OF PROTEIN MATURATION 12 82 0.0006194 0.002497
1155 ADHERENS JUNCTION ORGANIZATION 11 71 0.0006319 0.002546
1156 AMMONIUM ION METABOLIC PROCESS 19 169 0.0006338 0.002551
1157 CELLULAR RESPIRATION 17 143 0.0006362 0.002558
1158 REGULATION OF TUMOR NECROSIS FACTOR MEDIATED SIGNALING PATHWAY 9 50 0.0006366 0.002558
1159 AMIDE BIOSYNTHETIC PROCESS 42 507 0.0006394 0.002567
1160 REGULATION OF NUCLEASE ACTIVITY 6 23 0.0006668 0.002661
1161 REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 6 23 0.0006668 0.002661
1162 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE I PROMOTER 6 23 0.0006668 0.002661
1163 REGULATION OF CAMP MEDIATED SIGNALING 6 23 0.0006668 0.002661
1164 NUCLEOBASE CONTAINING SMALL MOLECULE INTERCONVERSION 6 23 0.0006668 0.002661
1165 NEGATIVE REGULATION OF ALPHA BETA T CELL ACTIVATION 6 23 0.0006668 0.002661
1166 REGULATION OF ALPHA BETA T CELL PROLIFERATION 6 23 0.0006668 0.002661
1167 LEARNING 16 131 0.0006748 0.00269
1168 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 21 197 0.0006857 0.002732
1169 EMBRYONIC PLACENTA DEVELOPMENT 12 83 0.0006924 0.002756
1170 OVARIAN FOLLICLE DEVELOPMENT 10 61 0.0007001 0.002784
1171 DEFENSE RESPONSE TO GRAM POSITIVE BACTERIUM 11 72 0.0007134 0.002835
1172 NEGATIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 13 95 0.00072 0.002858
1173 REGULATION OF B CELL MEDIATED IMMUNITY 8 41 0.000724 0.002862
1174 TRANSLESION SYNTHESIS 8 41 0.000724 0.002862
1175 CELL SUBSTRATE JUNCTION ASSEMBLY 8 41 0.000724 0.002862
1176 CELL PROJECTION ORGANIZATION 66 902 0.0007218 0.002862
1177 REGULATION OF LEUKOCYTE DEGRANULATION 8 41 0.000724 0.002862
1178 RESPONSE TO AMMONIUM ION 9 51 0.0007399 0.002918
1179 ARTERY MORPHOGENESIS 9 51 0.0007399 0.002918
1180 RESPONSE TO NICOTINE 9 51 0.0007399 0.002918
1181 MYD88 DEPENDENT TOLL LIKE RECEPTOR SIGNALING PATHWAY 7 32 0.0007561 0.002966
1182 REGULATION OF ORGAN FORMATION 7 32 0.0007561 0.002966
1183 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 7 32 0.0007561 0.002966
1184 GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR 7 32 0.0007561 0.002966
1185 TELOMERE MAINTENANCE VIA RECOMBINATION 7 32 0.0007561 0.002966
1186 NEGATIVE REGULATION OF SIGNAL TRANSDUCTION IN ABSENCE OF LIGAND 7 32 0.0007561 0.002966
1187 ORGANELLE DISASSEMBLY 20 185 0.0007626 0.002989
1188 NEGATIVE REGULATION OF T CELL RECEPTOR SIGNALING PATHWAY 5 16 0.0007728 0.003017
1189 GUANOSINE CONTAINING COMPOUND BIOSYNTHETIC PROCESS 5 16 0.0007728 0.003017
1190 DNA LIGATION 5 16 0.0007728 0.003017
1191 REGULATION OF TYROSINE PHOSPHORYLATION OF STAT1 PROTEIN 5 16 0.0007728 0.003017
1192 MITOCHONDRIAL ELECTRON TRANSPORT CYTOCHROME C TO OXYGEN 5 16 0.0007728 0.003017
1193 NEGATIVE REGULATION OF PROTEIN SECRETION 14 108 0.0007928 0.003092
1194 MAINTENANCE OF LOCATION IN CELL 13 96 0.0007962 0.003103
1195 PIGMENT METABOLIC PROCESS 10 62 0.0007987 0.00311
1196 HIPPOCAMPUS DEVELOPMENT 11 73 0.0008035 0.003126
1197 TRANSLATIONAL INITIATION 17 146 0.0008066 0.003133
1198 CELLULAR RESPONSE TO INSULIN STIMULUS 17 146 0.0008066 0.003133
1199 REGULATION OF MYELOID CELL APOPTOTIC PROCESS 6 24 0.0008526 0.0033
1200 BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 6 24 0.0008526 0.0033
1201 IMMUNOGLOBULIN PRODUCTION INVOLVED IN IMMUNOGLOBULIN MEDIATED IMMUNE RESPONSE 6 24 0.0008526 0.0033
1202 REGULATION OF EXECUTION PHASE OF APOPTOSIS 6 24 0.0008526 0.0033
1203 SOMATIC DIVERSIFICATION OF IMMUNE RECEPTORS 8 42 0.0008565 0.003307
1204 EPITHELIAL CELL MORPHOGENESIS 8 42 0.0008565 0.003307
1205 PROTEIN TARGETING TO MITOCHONDRION 9 52 0.0008565 0.003307
1206 REGULATION OF STRIATED MUSCLE CELL DIFFERENTIATION 12 85 0.0008602 0.003316
1207 POSITIVE REGULATION OF CHROMATIN MODIFICATION 12 85 0.0008602 0.003316
1208 SECOND MESSENGER MEDIATED SIGNALING 18 160 0.0008634 0.003326
1209 PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 16 134 0.0008649 0.003326
1210 MESENCHYMAL CELL DIFFERENTIATION 16 134 0.0008649 0.003326
1211 REGULATION OF GENE EXPRESSION EPIGENETIC 23 229 0.0008961 0.003443
1212 REGULATION OF STEROID METABOLIC PROCESS 11 74 0.0009028 0.003466
1213 CELLULAR SENESCENCE 7 33 0.0009196 0.003513
1214 SIGNAL TRANSDUCTION IN ABSENCE OF LIGAND 7 33 0.0009196 0.003513
1215 POSITIVE REGULATION OF RESPONSE TO CYTOKINE STIMULUS 7 33 0.0009196 0.003513
1216 EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 7 33 0.0009196 0.003513
1217 REGULATION OF BONE RESORPTION 7 33 0.0009196 0.003513
1218 CYTOPLASMIC PATTERN RECOGNITION RECEPTOR SIGNALING PATHWAY 7 33 0.0009196 0.003513
1219 CELLULAR MACROMOLECULAR COMPLEX ASSEMBLY 55 727 0.0009241 0.003528
1220 CELL GROWTH 16 135 0.0009376 0.003576
1221 MALE SEX DIFFERENTIATION 17 148 0.0009407 0.003585
1222 POSITIVE REGULATION OF DNA REPLICATION 12 86 0.000956 0.00364
1223 MYELOID LEUKOCYTE ACTIVATION 13 98 0.000969 0.003681
1224 LYMPHOCYTE ACTIVATION INVOLVED IN IMMUNE RESPONSE 13 98 0.000969 0.003681
1225 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 13 98 0.000969 0.003681
1226 POSITIVE REGULATION OF CYTOSKELETON ORGANIZATION 19 175 0.0009699 0.003681
1227 REGULATION OF LEUKOCYTE MEDIATED CYTOTOXICITY 9 53 0.0009876 0.003745
1228 NEGATIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 18 162 0.0009981 0.003782
1229 REGULATION OF SUBSTRATE ADHESION DEPENDENT CELL SPREADING 8 43 0.001008 0.003812
1230 REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 8 43 0.001008 0.003812
1231 ARTERY DEVELOPMENT 11 75 0.001012 0.003826
1232 NUCLEUS ORGANIZATION 16 136 0.001015 0.003835
1233 POSITIVE REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 10 64 0.00103 0.003888
1234 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 14 111 0.001042 0.003925
1235 NEGATIVE REGULATION OF DNA METABOLIC PROCESS 14 111 0.001042 0.003925
1236 NEGATIVE REGULATION OF ALCOHOL BIOSYNTHETIC PROCESS 5 17 0.001051 0.00395
1237 NEGATIVE REGULATION OF CELL AGING 5 17 0.001051 0.00395
1238 POSITIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC SIGNALING PATHWAY 5 17 0.001051 0.00395
1239 INTRACELLULAR PROTEIN TRANSPORT 58 781 0.001054 0.003958
1240 NEGATIVE REGULATION OF TRANSMEMBRANE TRANSPORT 12 87 0.001061 0.00398
1241 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 20 190 0.001064 0.003989
1242 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 13 99 0.001067 0.003996
1243 REGULATION OF TRANSFORMING GROWTH FACTOR BETA PRODUCTION 6 25 0.001076 0.004021
1244 POSITIVE REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION 6 25 0.001076 0.004021
1245 EPITHELIAL CELL APOPTOTIC PROCESS 6 25 0.001076 0.004021
1246 INOSITOL LIPID MEDIATED SIGNALING 15 124 0.001083 0.004045
1247 POSITIVE REGULATION OF CHROMOSOME ORGANIZATION 17 150 0.001093 0.00408
1248 HINDBRAIN DEVELOPMENT 16 137 0.001099 0.004096
1249 REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE 7 34 0.00111 0.004134
1250 ORGANIC CYCLIC COMPOUND CATABOLIC PROCESS 36 427 0.001111 0.004135
1251 POSTREPLICATION REPAIR 9 54 0.001134 0.004206
1252 REGULATION OF CELLULAR RESPONSE TO HEAT 11 76 0.001132 0.004206
1253 MICROTUBULE BASED PROCESS 42 522 0.001134 0.004206
1254 MULTICELLULAR ORGANISM GROWTH 11 76 0.001132 0.004206
1255 REGULATION OF MITOCHONDRIAL MEMBRANE POTENTIAL 9 54 0.001134 0.004206
1256 POSITIVE REGULATION OF NEURON DIFFERENTIATION 28 306 0.001146 0.004245
1257 METENCEPHALON DEVELOPMENT 13 100 0.001172 0.004335
1258 MODIFICATION OF MORPHOLOGY OR PHYSIOLOGY OF OTHER ORGANISM 13 100 0.001172 0.004335
1259 CELLULAR RESPONSE TO INTERLEUKIN 1 12 88 0.001174 0.004337
1260 OVULATION CYCLE PROCESS 12 88 0.001174 0.004337
1261 MYELOID CELL DEVELOPMENT 8 44 0.00118 0.004343
1262 NEGATIVE REGULATION OF JAK STAT CASCADE 8 44 0.00118 0.004343
1263 PROTEIN HOMOOLIGOMERIZATION 24 248 0.001177 0.004343
1264 NEGATIVE REGULATION OF STAT CASCADE 8 44 0.00118 0.004343
1265 MULTI ORGANISM METABOLIC PROCESS 16 138 0.001188 0.004369
1266 REGULATION OF CELLULAR COMPONENT SIZE 30 337 0.001206 0.004434
1267 REGULATION OF KIDNEY DEVELOPMENT 9 55 0.001299 0.004765
1268 NEGATIVE REGULATION OF DNA REPLICATION 9 55 0.001299 0.004765
1269 NEGATIVE REGULATION OF INTERLEUKIN 6 PRODUCTION 7 35 0.001329 0.004863
1270 NEGATIVE REGULATION OF EPITHELIAL CELL APOPTOTIC PROCESS 7 35 0.001329 0.004863
1271 REGULATION OF GLYCOGEN METABOLIC PROCESS 7 35 0.001329 0.004863
1272 B CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE 7 35 0.001329 0.004863
1273 NEGATIVE REGULATION OF STRIATED MUSCLE CELL DIFFERENTIATION 6 26 0.001341 0.004883
1274 REGULATION OF TYPE 2 IMMUNE RESPONSE 6 26 0.001341 0.004883
1275 POSITIVE REGULATION OF B CELL MEDIATED IMMUNITY 6 26 0.001341 0.004883
1276 REGULATION OF NECROTIC CELL DEATH 6 26 0.001341 0.004883
1277 POSITIVE REGULATION OF IMMUNOGLOBULIN MEDIATED IMMUNE RESPONSE 6 26 0.001341 0.004883
1278 REGULATION OF P38MAPK CASCADE 6 26 0.001341 0.004883
1279 REGULATION OF ENDOTHELIAL CELL MIGRATION 14 114 0.001354 0.00492
1280 REGULATION OF EMBRYONIC DEVELOPMENT 14 114 0.001354 0.00492
1281 ENDOTHELIAL CELL DEVELOPMENT 8 45 0.001374 0.00498
1282 POSITIVE REGULATION OF INTERLEUKIN 8 PRODUCTION 8 45 0.001374 0.00498
1283 SUBSTANTIA NIGRA DEVELOPMENT 8 45 0.001374 0.00498
1284 NEGATIVE REGULATION OF CHROMATIN MODIFICATION 8 45 0.001374 0.00498
1285 REGULATION OF TOLERANCE INDUCTION 5 18 0.001397 0.005043
1286 REGULATION OF B CELL APOPTOTIC PROCESS 5 18 0.001397 0.005043
1287 TOLL LIKE RECEPTOR 4 SIGNALING PATHWAY 5 18 0.001397 0.005043
1288 REGULATION OF UBIQUITIN PROTEIN LIGASE ACTIVITY 5 18 0.001397 0.005043
1289 PROTEIN HYDROXYLATION 5 18 0.001397 0.005043
1290 REGULATION OF MITOTIC SPINDLE CHECKPOINT 4 11 0.001428 0.005106
1291 SEQUESTERING OF METAL ION 4 11 0.001428 0.005106
1292 LAGGING STRAND ELONGATION 4 11 0.001428 0.005106
1293 POSITIVE REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 4 11 0.001428 0.005106
1294 CARDIAC CELL FATE COMMITMENT 4 11 0.001428 0.005106
1295 REGULATION OF ATTACHMENT OF SPINDLE MICROTUBULES TO KINETOCHORE 4 11 0.001428 0.005106
1296 PROTEIN FOLDING IN ENDOPLASMIC RETICULUM 4 11 0.001428 0.005106
1297 REGULATION OF MITOTIC CELL CYCLE SPINDLE ASSEMBLY CHECKPOINT 4 11 0.001428 0.005106
1298 VIRAL LATENCY 4 11 0.001428 0.005106
1299 REGULATION OF OXIDATIVE STRESS INDUCED NEURON DEATH 4 11 0.001428 0.005106
1300 LEUKOCYTE MIGRATION INVOLVED IN INFLAMMATORY RESPONSE 4 11 0.001428 0.005106
1301 POSITIVE REGULATION OF OXIDATIVE STRESS INDUCED CELL DEATH 4 11 0.001428 0.005106
1302 REGULATION OF CELL MATRIX ADHESION 12 90 0.001433 0.00512
1303 AMEBOIDAL TYPE CELL MIGRATION 17 154 0.001462 0.005222
1304 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 14 115 0.001473 0.005257
1305 MACROMOLECULE DEACYLATION 10 67 0.001478 0.005267
1306 CELLULAR RESPONSE TO DRUG 10 67 0.001478 0.005267
1307 RNA SPLICING VIA TRANSESTERIFICATION REACTIONS 25 267 0.001496 0.005326
1308 REGULATION OF LIPID METABOLIC PROCESS 26 282 0.001517 0.005398
1309 NEGATIVE REGULATION OF HISTONE MODIFICATION 7 36 0.001581 0.005613
1310 REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 7 36 0.001581 0.005613
1311 POSITIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 7 36 0.001581 0.005613
1312 CEREBELLAR CORTEX DEVELOPMENT 8 46 0.001593 0.005646
1313 PEPTIDYL THREONINE MODIFICATION 8 46 0.001593 0.005646
1314 CARBOHYDRATE METABOLIC PROCESS 50 662 0.001604 0.005678
1315 FC EPSILON RECEPTOR SIGNALING PATHWAY 16 142 0.001607 0.005686
1316 TUBE FORMATION 15 129 0.00162 0.005725
1317 REGULATION OF CAMP METABOLIC PROCESS 15 129 0.00162 0.005725
1318 SULFUR COMPOUND METABOLIC PROCESS 31 359 0.001639 0.005788
1319 SKELETAL MUSCLE TISSUE REGENERATION 6 27 0.001654 0.005804
1320 POSITIVE REGULATION OF HEART GROWTH 6 27 0.001654 0.005804
1321 NEGATIVE REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE 6 27 0.001654 0.005804
1322 REGULATION OF ASTROCYTE DIFFERENTIATION 6 27 0.001654 0.005804
1323 DNA CATABOLIC PROCESS 6 27 0.001654 0.005804
1324 NEGATIVE REGULATION OF ENDOTHELIAL CELL APOPTOTIC PROCESS 6 27 0.001654 0.005804
1325 POSITIVE REGULATION OF NF KAPPAB IMPORT INTO NUCLEUS 6 27 0.001654 0.005804
1326 HETEROTYPIC CELL CELL ADHESION 6 27 0.001654 0.005804
1327 CARDIAC CHAMBER MORPHOGENESIS 13 104 0.001686 0.005911
1328 COVALENT CHROMATIN MODIFICATION 30 345 0.001736 0.006082
1329 REGULATION OF INFLAMMATORY RESPONSE TO ANTIGENIC STIMULUS 5 19 0.00182 0.00632
1330 CELLULAR RESPONSE TO FLUID SHEAR STRESS 5 19 0.00182 0.00632
1331 VENTRICULAR CARDIAC MUSCLE CELL DIFFERENTIATION 5 19 0.00182 0.00632
1332 REGULATION OF WATER LOSS VIA SKIN 5 19 0.00182 0.00632
1333 NEGATIVE REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 5 19 0.00182 0.00632
1334 ERROR FREE TRANSLESION SYNTHESIS 5 19 0.00182 0.00632
1335 POSITIVE REGULATION OF ALPHA BETA T CELL PROLIFERATION 5 19 0.00182 0.00632
1336 POSITIVE REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 5 19 0.00182 0.00632
1337 REGULATION OF INTERLEUKIN 8 SECRETION 5 19 0.00182 0.00632
1338 ERROR PRONE TRANSLESION SYNTHESIS 5 19 0.00182 0.00632
1339 MUSCLE CELL CELLULAR HOMEOSTASIS 5 19 0.00182 0.00632
1340 ASTROCYTE DEVELOPMENT 5 19 0.00182 0.00632
1341 THYMUS DEVELOPMENT 8 47 0.001839 0.006381
1342 TRICARBOXYLIC ACID METABOLIC PROCESS 7 37 0.001869 0.006476
1343 MODULATION BY VIRUS OF HOST MORPHOLOGY OR PHYSIOLOGY 7 37 0.001869 0.006476
1344 POSITIVE REGULATION OF BLOOD CIRCULATION 12 93 0.001906 0.0066
1345 POSITIVE REGULATION OF ANION TRANSPORT 9 58 0.001908 0.006601
1346 PHENOL CONTAINING COMPOUND METABOLIC PROCESS 11 81 0.00192 0.006639
1347 REGULATION OF EXOCYTOSIS 19 186 0.001988 0.006866
1348 REGULATION OF T CELL RECEPTOR SIGNALING PATHWAY 6 28 0.002019 0.006948
1349 POSITIVE REGULATION OF LEUKOCYTE APOPTOTIC PROCESS 6 28 0.002019 0.006948
1350 POSITIVE REGULATION OF SUBSTRATE ADHESION DEPENDENT CELL SPREADING 6 28 0.002019 0.006948
1351 NEGATIVE REGULATION OF DENDRITE DEVELOPMENT 6 28 0.002019 0.006948
1352 REGULATION OF ENDOPLASMIC RETICULUM UNFOLDED PROTEIN RESPONSE 6 28 0.002019 0.006948
1353 REGULATION OF DENDRITIC CELL DIFFERENTIATION 4 12 0.002059 0.007034
1354 INTRA S DNA DAMAGE CHECKPOINT 4 12 0.002059 0.007034
1355 REGULATION OF T CELL TOLERANCE INDUCTION 4 12 0.002059 0.007034
1356 REGULATION OF MESENCHYMAL CELL APOPTOTIC PROCESS 4 12 0.002059 0.007034
1357 X4 HYDROXYPROLINE METABOLIC PROCESS 4 12 0.002059 0.007034
1358 POSITIVE REGULATION OF CATENIN IMPORT INTO NUCLEUS 4 12 0.002059 0.007034
1359 MYELIN MAINTENANCE 4 12 0.002059 0.007034
1360 POSITIVE REGULATION OF ASTROCYTE DIFFERENTIATION 4 12 0.002059 0.007034
1361 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 4 12 0.002059 0.007034
1362 POSITIVE REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 4 12 0.002059 0.007034
1363 MUSCLE ORGAN MORPHOGENESIS 10 70 0.002073 0.007075
1364 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 8 48 0.002114 0.0072
1365 REGULATION OF INTERLEUKIN 1 BETA PRODUCTION 8 48 0.002114 0.0072
1366 COLUMNAR CUBOIDAL EPITHELIAL CELL DEVELOPMENT 8 48 0.002114 0.0072
1367 JNK CASCADE 11 82 0.002122 0.007217
1368 REGULATION OF TRANSLATIONAL INITIATION 11 82 0.002122 0.007217
1369 REGULATION OF EPITHELIAL CELL APOPTOTIC PROCESS 9 59 0.002156 0.007327
1370 PLATELET DEGRANULATION 13 107 0.002183 0.007413
1371 POSITIVE REGULATION OF PURINE NUCLEOTIDE METABOLIC PROCESS 15 133 0.002196 0.007426
1372 BONE MINERALIZATION 7 38 0.002196 0.007426
1373 POSITIVE REGULATION OF DNA REPAIR 7 38 0.002196 0.007426
1374 SUBSTRATE ADHESION DEPENDENT CELL SPREADING 7 38 0.002196 0.007426
1375 POSITIVE REGULATION OF NUCLEOTIDE METABOLIC PROCESS 15 133 0.002196 0.007426
1376 MESENCHYME MORPHOGENESIS 7 38 0.002196 0.007426
1377 GLYCOSYL COMPOUND BIOSYNTHETIC PROCESS 14 120 0.002213 0.007478
1378 RNA SPLICING 31 367 0.002306 0.007788
1379 NEGATIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 10 71 0.002309 0.00779
1380 INTERMEDIATE FILAMENT ORGANIZATION 5 20 0.00233 0.007834
1381 POSITIVE REGULATION OF EPIDERMAL CELL DIFFERENTIATION 5 20 0.00233 0.007834
1382 PROTEIN ADP RIBOSYLATION 5 20 0.00233 0.007834
1383 NEGATIVE REGULATION OF ANTIGEN RECEPTOR MEDIATED SIGNALING PATHWAY 5 20 0.00233 0.007834
1384 PROTEIN HOMOTRIMERIZATION 5 20 0.00233 0.007834
1385 REGULATION OF ERBB SIGNALING PATHWAY 11 83 0.00234 0.007851
1386 NIK NF KAPPAB SIGNALING 11 83 0.00234 0.007851
1387 NUCLEOSIDE MONOPHOSPHATE BIOSYNTHETIC PROCESS 11 83 0.00234 0.007851
1388 ORGANELLE LOCALIZATION 34 415 0.002406 0.008067
1389 NEGATIVE REGULATION OF VIRAL GENOME REPLICATION 8 49 0.00242 0.0081
1390 CARDIAC CELL DEVELOPMENT 8 49 0.00242 0.0081
1391 EPIDERMIS MORPHOGENESIS 6 29 0.002442 0.008109
1392 REGULATION OF MEIOTIC NUCLEAR DIVISION 6 29 0.002442 0.008109
1393 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 6 29 0.002442 0.008109
1394 REGULATION OF EXTRACELLULAR MATRIX ORGANIZATION 6 29 0.002442 0.008109
1395 SOMATIC DIVERSIFICATION OF IMMUNOGLOBULINS 6 29 0.002442 0.008109
1396 PROTEIN IMPORT INTO NUCLEUS TRANSLOCATION 6 29 0.002442 0.008109
1397 MAINTENANCE OF PROTEIN LOCALIZATION IN ORGANELLE 6 29 0.002442 0.008109
1398 POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 6 29 0.002442 0.008109
1399 REGULATION OF OLIGODENDROCYTE DIFFERENTIATION 6 29 0.002442 0.008109
1400 OLIGODENDROCYTE DIFFERENTIATION 9 60 0.002428 0.008109
1401 POSITIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 6 29 0.002442 0.008109
1402 DIGESTIVE SYSTEM DEVELOPMENT 16 148 0.002464 0.008177
1403 NEGATIVE REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 7 39 0.002565 0.008501
1404 POSITIVE REGULATION OF CELL KILLING 7 39 0.002565 0.008501
1405 CYTOKINESIS 11 84 0.002577 0.008527
1406 POSITIVE REGULATION OF CYCLIC NUCLEOTIDE METABOLIC PROCESS 13 109 0.002576 0.008527
1407 LOCALIZATION WITHIN MEMBRANE 14 122 0.002584 0.008546
1408 NEURAL TUBE DEVELOPMENT 16 149 0.002638 0.008719
1409 NEGATIVE REGULATION OF CATION TRANSMEMBRANE TRANSPORT 9 61 0.002727 0.009007
1410 EYE MORPHOGENESIS 15 136 0.002731 0.009013
1411 POSITIVE REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 8 50 0.002759 0.0091
1412 ACUTE INFLAMMATORY RESPONSE 10 73 0.002846 0.009378
1413 POSITIVE REGULATION OF KERATINOCYTE DIFFERENTIATION 4 13 0.00286 0.009384
1414 REGULATION OF IRE1 MEDIATED UNFOLDED PROTEIN RESPONSE 4 13 0.00286 0.009384
1415 HEPATOCYTE APOPTOTIC PROCESS 4 13 0.00286 0.009384
1416 REGULATION OF TRANSLATIONAL INITIATION IN RESPONSE TO STRESS 4 13 0.00286 0.009384
1417 NEGATIVE REGULATION OF DNA TEMPLATED TRANSCRIPTION ELONGATION 4 13 0.00286 0.009384
1418 REGULATION OF MHC CLASS II BIOSYNTHETIC PROCESS 4 13 0.00286 0.009384
1419 REGULATION OF OSSIFICATION 18 178 0.002874 0.009424
1420 SMOOTH MUSCLE CELL DIFFERENTIATION 6 30 0.002928 0.009552
1421 NEGATIVE REGULATION OF B CELL ACTIVATION 6 30 0.002928 0.009552
1422 REPRODUCTIVE BEHAVIOR 6 30 0.002928 0.009552
1423 RESPONSE TO ATP 6 30 0.002928 0.009552
1424 CELLULAR RESPONSE TO ESTRADIOL STIMULUS 6 30 0.002928 0.009552
1425 OSTEOCLAST DIFFERENTIATION 6 30 0.002928 0.009552
1426 CELLULAR RESPONSE TO VASCULAR ENDOTHELIAL GROWTH FACTOR STIMULUS 6 30 0.002928 0.009552
1427 MAST CELL ACTIVATION 5 21 0.002936 0.009554
1428 T HELPER 1 TYPE IMMUNE RESPONSE 5 21 0.002936 0.009554
1429 REGULATION OF MEMBRANE PROTEIN ECTODOMAIN PROTEOLYSIS 5 21 0.002936 0.009554
1430 FIBRINOLYSIS 5 21 0.002936 0.009554
1431 REGULATION OF MEIOTIC CELL CYCLE 7 40 0.00298 0.009677
1432 POSITIVE REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS 12 98 0.002977 0.009677
1433 PROTEIN TRIMERIZATION 7 40 0.00298 0.009677
1434 SISTER CHROMATID COHESION 13 111 0.003026 0.00982
1435 CARDIAC VENTRICLE MORPHOGENESIS 9 62 0.003055 0.009898
1436 POSITIVE REGULATION OF NUCLEAR DIVISION 9 62 0.003055 0.009898
NumGOOverlapSizeP ValueAdj. P Value
1 ENZYME BINDING 227 1737 2.21e-45 2.053e-42
2 IDENTICAL PROTEIN BINDING 158 1209 7.029e-31 3.265e-28
3 RECEPTOR BINDING 170 1476 1.023e-26 3.167e-24
4 KINASE BINDING 97 606 1.689e-25 3.922e-23
5 MACROMOLECULAR COMPLEX BINDING 152 1399 2.812e-21 5.224e-19
6 ADENYL NUCLEOTIDE BINDING 156 1514 1.415e-19 2.191e-17
7 RIBONUCLEOTIDE BINDING 176 1860 3.103e-18 4.118e-16
8 UBIQUITIN LIKE PROTEIN LIGASE BINDING 50 264 1.117e-16 1.297e-14
9 KINASE ACTIVITY 97 842 2.438e-15 2.265e-13
10 PROTEIN COMPLEX BINDING 104 935 2.351e-15 2.265e-13
11 PROTEIN KINASE ACTIVITY 80 640 9.749e-15 8.234e-13
12 PROTEIN DIMERIZATION ACTIVITY 117 1149 2.171e-14 1.681e-12
13 POLY A RNA BINDING 118 1170 3.267e-14 2.334e-12
14 RNA BINDING 146 1598 7.106e-14 4.715e-12
15 PROTEIN HOMODIMERIZATION ACTIVITY 83 722 3.261e-13 2.02e-11
16 PROTEIN DOMAIN SPECIFIC BINDING 75 624 5.217e-13 3.029e-11
17 CYTOKINE RECEPTOR BINDING 44 271 2.144e-12 1.172e-10
18 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 99 992 8.69e-12 4.485e-10
19 PROTEIN SERINE THREONINE KINASE ACTIVITY 58 445 9.569e-12 4.679e-10
20 TRANSCRIPTION FACTOR BINDING 62 524 1.12e-10 5.201e-09
21 ENZYME REGULATOR ACTIVITY 93 959 1.833e-10 8.108e-09
22 MOLECULAR FUNCTION REGULATOR 119 1353 2.246e-10 9.486e-09
23 DOUBLE STRANDED DNA BINDING 78 764 5.728e-10 2.314e-08
24 HISTONE DEACETYLASE BINDING 23 105 1.078e-09 4.171e-08
25 CYTOKINE ACTIVITY 34 219 2.295e-09 8.527e-08
26 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY BINDING 15 47 3.437e-09 1.228e-07
27 VIRUS RECEPTOR ACTIVITY 18 70 4.629e-09 1.588e-07
28 SEQUENCE SPECIFIC DNA BINDING 94 1037 4.787e-09 1.588e-07
29 REGULATORY REGION NUCLEIC ACID BINDING 79 818 5.634e-09 1.805e-07
30 CXCR CHEMOKINE RECEPTOR BINDING 9 16 1.304e-08 4.039e-07
31 CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 19 86 2.597e-08 7.782e-07
32 PROTEIN TYROSINE KINASE ACTIVITY 28 176 3.436e-08 9.975e-07
33 CHROMATIN BINDING 49 435 5.008e-08 1.41e-06
34 G PROTEIN COUPLED RECEPTOR BINDING 34 259 1.626e-07 4.442e-06
35 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 31 226 2.12e-07 5.626e-06
36 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 39 328 2.906e-07 7.498e-06
37 CORE PROMOTER BINDING 24 152 3.725e-07 9.106e-06
38 CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 11 34 3.702e-07 9.106e-06
39 KINASE REGULATOR ACTIVITY 27 186 4.074e-07 9.704e-06
40 OXIDOREDUCTASE ACTIVITY 66 719 6.703e-07 1.557e-05
41 INTEGRIN BINDING 19 105 7.23e-07 1.638e-05
42 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 37 315 7.873e-07 1.742e-05
43 TUMOR NECROSIS FACTOR RECEPTOR BINDING 10 30 9.25e-07 1.998e-05
44 PROTEIN HETERODIMERIZATION ACTIVITY 48 468 1.108e-06 2.339e-05
45 HEAT SHOCK PROTEIN BINDING 17 89 1.256e-06 2.593e-05
46 PROTEIN C TERMINUS BINDING 26 186 1.384e-06 2.736e-05
47 CELL ADHESION MOLECULE BINDING 26 186 1.384e-06 2.736e-05
48 PROTEIN PHOSPHATASE BINDING 20 120 1.444e-06 2.795e-05
49 HISTONE KINASE ACTIVITY 8 19 1.494e-06 2.832e-05
50 UNFOLDED PROTEIN BINDING 18 100 1.526e-06 2.836e-05
51 ION CHANNEL BINDING 19 111 1.739e-06 3.168e-05
52 SINGLE STRANDED DNA BINDING 17 93 2.377e-06 4.246e-05
53 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 58 629 2.789e-06 4.888e-05
54 FOUR WAY JUNCTION DNA BINDING 7 15 3.001e-06 5.163e-05
55 STRUCTURE SPECIFIC DNA BINDING 19 118 4.455e-06 7.525e-05
56 DRUG BINDING 18 109 5.48e-06 9.091e-05
57 CHAPERONE BINDING 15 81 7.822e-06 0.0001275
58 ELECTRON CARRIER ACTIVITY 18 112 8.114e-06 0.00013
59 NF KAPPAB BINDING 9 30 8.764e-06 0.000138
60 ENDOPEPTIDASE ACTIVITY 44 448 9.396e-06 0.0001455
61 NON MEMBRANE SPANNING PROTEIN TYROSINE KINASE ACTIVITY 11 46 1.006e-05 0.0001532
62 DOUBLE STRANDED RNA BINDING 13 64 1.099e-05 0.0001646
63 DNA SECONDARY STRUCTURE BINDING 8 24 1.168e-05 0.0001722
64 PHOSPHATASE BINDING 22 162 1.404e-05 0.0002038
65 CHEMOKINE ACTIVITY 11 48 1.558e-05 0.0002226
66 CHEMOKINE RECEPTOR BINDING 12 57 1.626e-05 0.0002288
67 SERINE HYDROLASE ACTIVITY 28 242 2.225e-05 0.0003085
68 GLYCOSAMINOGLYCAN BINDING 25 205 2.489e-05 0.00034
69 EXTRACELLULAR MATRIX BINDING 11 51 2.87e-05 0.0003864
70 DEOXYRIBONUCLEASE ACTIVITY 13 70 3.025e-05 0.0004014
71 RECEPTOR SIGNALING PROTEIN ACTIVITY 22 172 3.611e-05 0.0004724
72 PROTEIN N TERMINUS BINDING 16 103 3.925e-05 0.0005065
73 CYCLIN DEPENDENT PROTEIN SERINE THREONINE KINASE REGULATOR ACTIVITY 8 28 4.144e-05 0.0005273
74 PROTEASE BINDING 16 104 4.432e-05 0.0005563
75 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 51 588 5.621e-05 0.0006963
76 OXIDOREDUCTASE ACTIVITY ACTING ON NAD P H OXYGEN AS ACCEPTOR 6 16 7.102e-05 0.0008682
77 LOW DENSITY LIPOPROTEIN PARTICLE RECEPTOR BINDING 6 17 0.0001052 0.00127
78 DEATH RECEPTOR ACTIVITY 7 24 0.0001095 0.001304
79 ENZYME INHIBITOR ACTIVITY 36 378 0.0001114 0.001311
80 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC BINDING 14 90 0.0001157 0.001344
81 ANTIOXIDANT ACTIVITY 12 70 0.0001362 0.001562
82 CORE PROMOTER PROXIMAL REGION DNA BINDING 35 371 0.0001659 0.001857
83 PROTEIN CHANNEL ACTIVITY 5 12 0.0001651 0.001857
84 PROTEIN DEACETYLASE ACTIVITY 9 43 0.0001947 0.002154
85 NAD BINDING 10 53 0.0002156 0.002356
86 HEPARIN BINDING 19 157 0.0002494 0.002676
87 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 11 64 0.0002506 0.002676
88 PHOSPHOLIPASE INHIBITOR ACTIVITY 5 13 0.0002575 0.002718
89 HYDROLASE ACTIVITY ACTING ON ACID ANHYDRIDES 63 820 0.0002681 0.002799
90 GROWTH FACTOR ACTIVITY 19 160 0.0003183 0.003286
91 PEPTIDASE REGULATOR ACTIVITY 23 214 0.000347 0.003543
92 CALCIUM DEPENDENT CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 6 21 0.0003899 0.003937
93 UBIQUITIN LIKE PROTEIN CONJUGATING ENZYME ACTIVITY 7 29 0.0003986 0.003981
94 DNA DEPENDENT ATPASE ACTIVITY 12 79 0.0004378 0.004327
95 HSP70 PROTEIN BINDING 7 30 0.0004981 0.004871
96 PROTEIN SERINE THREONINE TYROSINE KINASE ACTIVITY 8 39 0.0005084 0.004872
97 LIPOPROTEIN PARTICLE RECEPTOR BINDING 6 22 0.000514 0.004872
98 MACROMOLECULE TRANSMEMBRANE TRANSPORTER ACTIVITY 6 22 0.000514 0.004872
99 CYTOKINE BINDING 13 92 0.0005271 0.004897
100 RECEPTOR SIGNALING PROTEIN SERINE THREONINE KINASE ACTIVITY 13 92 0.0005271 0.004897
101 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 12 81 0.0005529 0.005041
102 CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY INVOLVED IN APOPTOTIC PROCESS 5 15 0.0005535 0.005041
103 OXIDOREDUCTASE ACTIVITY ACTING ON NAD P H 13 93 0.0005859 0.005233
104 ENHANCER BINDING 13 93 0.0005859 0.005233
105 CYSTEINE TYPE PEPTIDASE ACTIVITY 20 184 0.0007121 0.0063
106 MHC CLASS II PROTEIN COMPLEX BINDING 5 16 0.0007728 0.006773
107 OXIDOREDUCTASE ACTIVITY ACTING ON PEROXIDE AS ACCEPTOR 8 42 0.0008565 0.007436
108 DAMAGED DNA BINDING 10 63 0.0009085 0.007743
109 AMIDE BINDING 26 272 0.0009012 0.007743
110 NAD DEPENDENT PROTEIN DEACETYLASE ACTIVITY 5 17 0.001051 0.008876
111 ATPASE ACTIVITY 36 427 0.001111 0.009296
112 STRUCTURAL CONSTITUENT OF CYTOSKELETON 13 100 0.001172 0.009636
113 RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC DNA BINDING 10 65 0.001165 0.009636
114 CYTOSKELETAL PROTEIN BINDING 60 819 0.001206 0.009705
115 SULFUR COMPOUND BINDING 23 234 0.001199 0.009705
116 COFACTOR BINDING 25 263 0.001212 0.009705
NumGOOverlapSizeP ValueAdj. P Value
1 CELL SURFACE 109 757 1.122e-24 6.55e-22
2 EXTRACELLULAR SPACE 157 1376 3.49e-24 1.019e-21
3 SIDE OF MEMBRANE 70 428 3.641e-19 7.089e-17
4 CELL SUBSTRATE JUNCTION 64 398 3.065e-17 4.475e-15
5 ANCHORING JUNCTION 72 489 4.189e-17 4.892e-15
6 PERINUCLEAR REGION OF CYTOPLASM 83 642 4.181e-16 3.488e-14
7 MITOCHONDRION 155 1633 3.708e-16 3.488e-14
8 NUCLEAR CHROMOSOME 72 523 1.576e-15 1.151e-13
9 CHROMOSOME 99 880 5.695e-15 3.695e-13
10 MYELIN SHEATH 37 168 7.833e-15 4.575e-13
11 CHROMOSOMAL REGION 50 330 1.001e-12 5.316e-11
12 CELL JUNCTION 112 1151 1.664e-12 8.096e-11
13 EXTERNAL SIDE OF PLASMA MEMBRANE 40 238 7.115e-12 3.036e-10
14 ENVELOPE 106 1090 7.278e-12 3.036e-10
15 PIGMENT GRANULE 24 103 1.198e-10 4.665e-09
16 CHROMOSOME TELOMERIC REGION 30 162 2.676e-10 9.767e-09
17 MITOCHONDRIAL ENVELOPE 73 691 4.655e-10 1.599e-08
18 MITOCHONDRIAL PART 91 953 6.47e-10 2.099e-08
19 VACUOLE 106 1180 7.529e-10 2.283e-08
20 MEMBRANE MICRODOMAIN 41 288 7.817e-10 2.283e-08
21 MEMBRANE PROTEIN COMPLEX 94 1020 2.08e-09 5.785e-08
22 INTRACELLULAR VESICLE 109 1259 3.388e-09 8.994e-08
23 LYTIC VACUOLE 58 526 6.432e-09 1.633e-07
24 CHROMATIN 51 441 1.119e-08 2.722e-07
25 CONDENSED CHROMOSOME 30 195 2.468e-08 5.766e-07
26 CONDENSED NUCLEAR CHROMOSOME 18 85 1.202e-07 2.699e-06
27 MEMBRANE REGION 95 1134 1.772e-07 3.833e-06
28 CYTOSKELETON 145 1967 2.74e-07 5.715e-06
29 MITOCHONDRIAL MEMBRANE PART 26 173 3.341e-07 6.727e-06
30 NUCLEAR CHROMOSOME TELOMERIC REGION 22 132 4.363e-07 7.962e-06
31 CONDENSED CHROMOSOME OUTER KINETOCHORE 7 12 4.206e-07 7.962e-06
32 MIDBODY 22 132 4.363e-07 7.962e-06
33 HETEROCHROMATIN 15 67 6.306e-07 1.116e-05
34 SPINDLE 35 289 7.598e-07 1.233e-05
35 MITOCHONDRIAL PROTEIN COMPLEX 22 136 7.4e-07 1.233e-05
36 EXTRINSIC COMPONENT OF PLASMA MEMBRANE 22 136 7.4e-07 1.233e-05
37 EXTRINSIC COMPONENT OF MEMBRANE 32 252 7.903e-07 1.247e-05
38 INNER MITOCHONDRIAL MEMBRANE PROTEIN COMPLEX 19 106 8.41e-07 1.268e-05
39 VACUOLAR PART 64 694 8.47e-07 1.268e-05
40 PROTEIN COMPLEX INVOLVED IN CELL ADHESION 10 30 9.25e-07 1.318e-05
41 CYTOSKELETAL PART 111 1436 9.044e-07 1.318e-05
42 EXTRACELLULAR MATRIX 45 426 1.075e-06 1.494e-05
43 CATALYTIC COMPLEX 86 1038 1.111e-06 1.509e-05
44 CELL LEADING EDGE 39 350 1.514e-06 2.01e-05
45 TRANSCRIPTION FACTOR COMPLEX 35 298 1.558e-06 2.022e-05
46 OUTER MEMBRANE 26 190 2.079e-06 2.64e-05
47 ORGANELLE ENVELOPE LUMEN 16 83 2.261e-06 2.81e-05
48 ENDOSOMAL PART 44 430 3.282e-06 3.993e-05
49 MICROTUBULE CYTOSKELETON 86 1068 3.488e-06 4.157e-05
50 ENDOPLASMIC RETICULUM 120 1631 3.712e-06 4.336e-05
51 LYSOSOMAL LUMEN 16 88 5.033e-06 5.763e-05
52 INTRINSIC COMPONENT OF PLASMA MEMBRANE 120 1649 6.269e-06 7.041e-05
53 NUCLEAR CHROMATIN 33 291 6.558e-06 7.227e-05
54 RUFFLE 22 156 7.611e-06 8.231e-05
55 PORE COMPLEX 7 17 8.319e-06 8.833e-05
56 ENDOCYTIC VESICLE 30 256 8.923e-06 9.305e-05
57 ENDOSOME 67 793 9.416e-06 9.648e-05
58 CYTOPLASMIC SIDE OF MEMBRANE 23 170 9.609e-06 9.675e-05
59 OXIDOREDUCTASE COMPLEX 16 93 1.052e-05 0.0001042
60 CELL BODY 47 494 1.09e-05 0.0001061
61 ORGANELLE INNER MEMBRANE 49 525 1.192e-05 0.0001088
62 VACUOLAR LUMEN 18 115 1.183e-05 0.0001088
63 LAMELLIPODIUM 23 172 1.168e-05 0.0001088
64 PLASMA MEMBRANE PROTEIN COMPLEX 48 510 1.173e-05 0.0001088
65 CELL CELL JUNCTION 39 383 1.312e-05 0.0001161
66 CONDENSED NUCLEAR CHROMOSOME CENTROMERIC REGION 7 18 1.304e-05 0.0001161
67 VACUOLAR MEMBRANE 53 587 1.353e-05 0.0001179
68 LUMENAL SIDE OF MEMBRANE 9 33 2.069e-05 0.0001777
69 COP9 SIGNALOSOME 9 34 2.692e-05 0.0002279
70 SPINDLE MIDZONE 8 27 3.092e-05 0.0002579
71 CHROMOSOME CENTROMERIC REGION 22 174 4.316e-05 0.0003501
72 NUCLEOLUS 68 848 4.291e-05 0.0003501
73 PRONUCLEUS 6 15 4.631e-05 0.0003705
74 MITOTIC SPINDLE 11 55 6.028e-05 0.0004757
75 PHAGOCYTIC VESICLE 14 86 6.968e-05 0.0005426
76 NUCLEAR MATRIX 15 98 8.077e-05 0.0006206
77 NUCLEAR PERIPHERY 17 121 8.411e-05 0.0006379
78 CYCLIN DEPENDENT PROTEIN KINASE HOLOENZYME COMPLEX 8 31 9.227e-05 0.0006909
79 SMN SM PROTEIN COMPLEX 6 17 0.0001052 0.0007779
80 RESPIRATORY CHAIN 13 80 0.0001278 0.0009153
81 CONDENSED CHROMOSOME CENTROMERIC REGION 15 102 0.0001285 0.0009153
82 MICROTUBULE ORGANIZING CENTER 52 623 0.000127 0.0009153
83 CELL PROJECTION 121 1786 0.0001378 0.0009697
84 SPINDLE POLE 17 126 0.0001398 0.0009723
85 RECEPTOR COMPLEX 32 327 0.0001603 0.001102
86 METHYLOSOME 5 12 0.0001651 0.001121
87 NUCLEAR ENVELOPE 38 416 0.0001726 0.001159
88 REPLICATION FORK 11 62 0.0001873 0.001243
89 ENDOPLASMIC RETICULUM PART 84 1163 0.0002144 0.001407
90 SEX CHROMOSOME 7 27 0.000247 0.001603
91 FANCONI ANAEMIA NUCLEAR COMPLEX 5 13 0.0002575 0.001652
92 BASOLATERAL PLASMA MEMBRANE 23 211 0.000283 0.001796
93 PLASMA MEMBRANE RECEPTOR COMPLEX 20 175 0.0003729 0.002342
94 TRANSFERASE COMPLEX 55 703 0.0004192 0.002604
95 PHAGOCYTIC VESICLE MEMBRANE 10 58 0.0004625 0.002843
96 ENDOCYTIC VESICLE MEMBRANE 18 152 0.0004682 0.002848
97 CENTROSOME 41 487 0.0005361 0.003228
98 ROUGH ENDOPLASMIC RETICULUM 11 71 0.0006319 0.003715
99 BLOOD MICROPARTICLE 17 143 0.0006362 0.003715
100 SOMATODENDRITIC COMPARTMENT 51 650 0.0006285 0.003715
101 VESICLE LUMEN 14 106 0.0006564 0.003795
102 SUPRAMOLECULAR FIBER 52 670 0.0007152 0.004095
103 NUCLEAR HETEROCHROMATIN 7 32 0.0007561 0.004285
104 RIBONUCLEOPROTEIN COMPLEX 55 721 0.0007631 0.004285
105 NEURON PROJECTION 68 942 0.0008617 0.004703
106 INTRINSIC COMPONENT OF MITOCHONDRIAL MEMBRANE 9 52 0.0008565 0.004703
107 NUCLEAR UBIQUITIN LIGASE COMPLEX 8 42 0.0008565 0.004703
108 APICAL PART OF CELL 32 361 0.0009056 0.004897
109 IMMUNOLOGICAL SYNAPSE 7 33 0.0009196 0.004927
110 EXTRINSIC COMPONENT OF CYTOPLASMIC SIDE OF PLASMA MEMBRANE 13 98 0.000969 0.005098
111 PLASMA MEMBRANE REGION 67 929 0.0009609 0.005098
112 U1 SNRNP 5 17 0.001051 0.005431
113 ENDOCYTIC VESICLE LUMEN 5 17 0.001051 0.005431
114 CYTOPLASMIC VESICLE PART 47 601 0.001081 0.00554
115 UBIQUITIN LIGASE COMPLEX 25 262 0.001149 0.005833
116 NEURON PART 86 1265 0.001195 0.006015
117 EARLY ENDOSOME MEMBRANE 14 113 0.001242 0.006199
118 RNA POLYMERASE II TRANSCRIPTION FACTOR COMPLEX 13 101 0.001286 0.006366
119 GOLGI APPARATUS 96 1445 0.001303 0.006397
120 NUCLEAR TRANSCRIPTION FACTOR COMPLEX 15 127 0.001384 0.006734
121 PHAGOCYTIC CUP 5 18 0.001397 0.006742
122 INTRINSIC COMPONENT OF ORGANELLE MEMBRANE 26 281 0.001443 0.006795
123 MCM COMPLEX 4 11 0.001428 0.006795
124 PROTEINACEOUS EXTRACELLULAR MATRIX 31 356 0.001436 0.006795
125 MHC PROTEIN COMPLEX 6 27 0.001654 0.007727
126 ACTIN FILAMENT BUNDLE 9 57 0.001684 0.007804
127 U2 SNRNP 5 19 0.00182 0.00837
128 CYTOPLASMIC REGION 26 287 0.001943 0.008864
129 ACTIN FILAMENT 10 70 0.002073 0.009383

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04110_Cell_cycle 45 128 6.846e-27 1.212e-24
2 hsa04141_Protein_processing_in_endoplasmic_reticulum 40 168 3.518e-17 3.113e-15
3 hsa04115_p53_signaling_pathway 23 69 7.942e-14 4.426e-12
4 hsa04510_Focal_adhesion 39 200 1e-13 4.426e-12
5 hsa04810_Regulation_of_actin_cytoskeleton 37 214 1.855e-11 6.566e-10
6 hsa04380_Osteoclast_differentiation 27 128 9.705e-11 2.569e-09
7 hsa04145_Phagosome 30 156 1.016e-10 2.569e-09
8 hsa04114_Oocyte_meiosis 25 114 1.989e-10 4.402e-09
9 hsa04010_MAPK_signaling_pathway 40 268 3.014e-10 5.927e-09
10 hsa04210_Apoptosis 21 89 1.348e-09 2.386e-08
11 hsa04670_Leukocyte_transendothelial_migration 24 117 1.929e-09 3.001e-08
12 hsa04650_Natural_killer_cell_mediated_cytotoxicity 26 136 2.035e-09 3.001e-08
13 hsa04620_Toll.like_receptor_signaling_pathway 22 102 3.371e-09 4.589e-08
14 hsa04612_Antigen_processing_and_presentation 19 78 4.629e-09 5.852e-08
15 hsa04722_Neurotrophin_signaling_pathway 24 127 1.071e-08 1.264e-07
16 hsa04914_Progesterone.mediated_oocyte_maturation 19 87 3.172e-08 3.509e-07
17 hsa04062_Chemokine_signaling_pathway 28 189 1.62e-07 1.687e-06
18 hsa04660_T_cell_receptor_signaling_pathway 20 108 2.511e-07 2.469e-06
19 hsa04666_Fc_gamma_R.mediated_phagocytosis 18 95 6.969e-07 6.183e-06
20 hsa04621_NOD.like_receptor_signaling_pathway 14 59 6.987e-07 6.183e-06
21 hsa04514_Cell_adhesion_molecules_.CAMs. 22 136 7.4e-07 6.237e-06
22 hsa04520_Adherens_junction 15 73 2.014e-06 1.621e-05
23 hsa04662_B_cell_receptor_signaling_pathway 15 75 2.882e-06 2.218e-05
24 hsa00480_Glutathione_metabolism 12 50 3.828e-06 2.823e-05
25 hsa03030_DNA_replication 10 36 5.985e-06 4.238e-05
26 hsa04370_VEGF_signaling_pathway 14 76 1.663e-05 0.0001132
27 hsa04672_Intestinal_immune_network_for_IgA_production 11 49 1.92e-05 0.0001215
28 hsa04012_ErbB_signaling_pathway 15 87 1.922e-05 0.0001215
29 hsa04664_Fc_epsilon_RI_signaling_pathway 14 79 2.626e-05 0.0001603
30 hsa04020_Calcium_signaling_pathway 22 177 5.607e-05 0.0003308
31 hsa04512_ECM.receptor_interaction 14 85 6.105e-05 0.0003486
32 hsa04310_Wnt_signaling_pathway 19 151 0.0001495 0.000827
33 hsa04144_Endocytosis 23 203 0.0001601 0.0008585
34 hsa04150_mTOR_signaling_pathway 10 52 0.0001828 0.0009519
35 hsa04350_TGF.beta_signaling_pathway 13 85 0.000239 0.001209
36 hsa04530_Tight_junction 17 133 0.0002709 0.001332
37 hsa04640_Hematopoietic_cell_lineage 13 88 0.0003394 0.001623
38 hsa04916_Melanogenesis 14 101 0.0003992 0.00186
39 hsa04630_Jak.STAT_signaling_pathway 18 155 0.0005926 0.00269
40 hsa04360_Axon_guidance 16 130 0.0006199 0.002728
41 hsa04622_RIG.I.like_receptor_signaling_pathway 11 71 0.0006319 0.002728
42 hsa03430_Mismatch_repair 6 23 0.0006668 0.00281
43 hsa04142_Lysosome 15 121 0.0008399 0.003457
44 hsa00860_Porphyrin_and_chlorophyll_metabolism 8 43 0.001008 0.004054
45 hsa04920_Adipocytokine_signaling_pathway 10 68 0.001659 0.006524
46 hsa00190_Oxidative_phosphorylation 15 132 0.002038 0.007842
47 hsa04910_Insulin_signaling_pathway 15 138 0.003145 0.01184
48 hsa04120_Ubiquitin_mediated_proteolysis 15 139 0.00337 0.01243
49 hsa04912_GnRH_signaling_pathway 12 101 0.003823 0.01381
50 hsa00330_Arginine_and_proline_metabolism 8 54 0.004504 0.01595
51 hsa03410_Base_excision_repair 6 34 0.005616 0.01949
52 hsa04720_Long.term_potentiation 9 70 0.006925 0.02357
53 hsa00270_Cysteine_and_methionine_metabolism 6 36 0.007487 0.025
54 hsa03040_Spliceosome 13 128 0.01001 0.03283
55 hsa03440_Homologous_recombination 5 28 0.01069 0.03439
56 hsa04540_Gap_junction 10 90 0.01248 0.03946
57 hsa00020_Citrate_cycle_.TCA_cycle. 5 30 0.0143 0.0444
58 hsa04974_Protein_digestion_and_absorption 9 81 0.01731 0.05281
59 hsa04730_Long.term_depression 8 70 0.02068 0.06204
60 hsa03420_Nucleotide_excision_repair 6 45 0.02162 0.06378
61 hsa04140_Regulation_of_autophagy 5 34 0.02379 0.06904
62 hsa04320_Dorso.ventral_axis_formation 4 25 0.03178 0.09072
63 hsa03010_Ribosome 9 92 0.03604 0.09997
64 hsa00601_Glycosphingolipid_biosynthesis_._lacto_and_neolacto_series 4 26 0.03615 0.09997
65 hsa00983_Drug_metabolism_._other_enzymes 6 52 0.04064 0.1107
66 hsa00670_One_carbon_pool_by_folate 3 18 0.05511 0.1435
67 hsa04340_Hedgehog_signaling_pathway 6 56 0.05513 0.1435
68 hsa04623_Cytosolic_DNA.sensing_pathway 6 56 0.05513 0.1435
69 hsa00040_Pentose_and_glucuronate_interconversions 4 32 0.06923 0.1764
70 hsa04970_Salivary_secretion 8 89 0.06978 0.1764
71 hsa04330_Notch_signaling_pathway 5 47 0.07856 0.1959
72 hsa04146_Peroxisome 7 79 0.09164 0.2253
73 hsa00910_Nitrogen_metabolism 3 23 0.1001 0.2427
74 hsa04610_Complement_and_coagulation_cascades 6 69 0.1211 0.2897
75 hsa03013_RNA_transport 11 152 0.1264 0.2984
76 hsa00534_Glycosaminoglycan_biosynthesis_._heparan_sulfate 3 26 0.1323 0.3074
77 hsa00980_Metabolism_of_xenobiotics_by_cytochrome_P450 6 71 0.1337 0.3074
78 hsa00052_Galactose_metabolism 3 27 0.1437 0.3261
79 hsa03450_Non.homologous_end.joining 2 14 0.1478 0.3311
80 hsa00604_Glycosphingolipid_biosynthesis_._ganglio_series 2 15 0.1653 0.3567
81 hsa00900_Terpenoid_backbone_biosynthesis 2 15 0.1653 0.3567
82 hsa02010_ABC_transporters 4 44 0.1672 0.3567
83 hsa04962_Vasopressin.regulated_water_reabsorption 4 44 0.1672 0.3567
84 hsa00230_Purine_metabolism 11 162 0.1712 0.3608
85 hsa04260_Cardiac_muscle_contraction 6 77 0.1749 0.3642
86 hsa03050_Proteasome 4 45 0.177 0.3642
87 hsa00970_Aminoacyl.tRNA_biosynthesis 5 63 0.1947 0.3916
88 hsa00360_Phenylalanine_metabolism 2 17 0.2011 0.3944
89 hsa00511_Other_glycan_degradation 2 17 0.2011 0.3944
90 hsa00250_Alanine._aspartate_and_glutamate_metabolism 3 32 0.205 0.3944
91 hsa00260_Glycine._serine_and_threonine_metabolism 3 32 0.205 0.3944
92 hsa04270_Vascular_smooth_muscle_contraction 8 116 0.2081 0.3953
93 hsa00240_Pyrimidine_metabolism 7 99 0.2111 0.3953
94 hsa00010_Glycolysis_._Gluconeogenesis 5 65 0.2122 0.3953
95 hsa00510_N.Glycan_biosynthesis 4 49 0.2176 0.4011
96 hsa04972_Pancreatic_secretion 7 101 0.2253 0.4112
97 hsa00531_Glycosaminoglycan_degradation 2 19 0.2378 0.4294
98 hsa03320_PPAR_signaling_pathway 5 70 0.2578 0.4603
99 hsa00982_Drug_metabolism_._cytochrome_P450 5 73 0.2862 0.5015
100 hsa04971_Gastric_acid_secretion 5 74 0.2958 0.5091
101 hsa03060_Protein_export 2 23 0.3115 0.5203
102 hsa04710_Circadian_rhythm_._mammal 2 23 0.3115 0.5203
103 hsa00600_Sphingolipid_metabolism 3 40 0.3116 0.5203
104 hsa00350_Tyrosine_metabolism 3 41 0.3252 0.5356
105 hsa00760_Nicotinate_and_nicotinamide_metabolism 2 24 0.3298 0.5356
106 hsa04977_Vitamin_digestion_and_absorption 2 24 0.3298 0.5356
107 hsa04960_Aldosterone.regulated_sodium_reabsorption 3 42 0.3388 0.5451
108 hsa00310_Lysine_degradation 3 44 0.3659 0.5731
109 hsa04973_Carbohydrate_digestion_and_absorption 3 44 0.3659 0.5731
110 hsa00030_Pentose_phosphate_pathway 2 27 0.3837 0.5958
111 hsa03018_RNA_degradation 4 71 0.4608 0.6912
112 hsa04976_Bile_secretion 4 71 0.4608 0.6912
113 hsa04742_Taste_transduction 3 52 0.4714 0.7012
114 hsa00500_Starch_and_sucrose_metabolism 3 54 0.4966 0.7325
115 hsa04130_SNARE_interactions_in_vesicular_transport 2 36 0.5318 0.7695
116 hsa04070_Phosphatidylinositol_signaling_system 4 78 0.5347 0.7695
117 hsa00590_Arachidonic_acid_metabolism 3 59 0.5567 0.7947
118 hsa03008_Ribosome_biogenesis_in_eukaryotes 4 81 0.5648 0.7998
119 hsa03015_mRNA_surveillance_pathway 4 83 0.5843 0.8143
120 hsa00620_Pyruvate_metabolism 2 40 0.5894 0.815
121 hsa00140_Steroid_hormone_biosynthesis 2 57 0.7753 1
122 hsa00562_Inositol_phosphate_metabolism 2 57 0.7753 1
123 hsa00564_Glycerophospholipid_metabolism 2 80 0.9081 1

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1 LINC00504 hsa-miR-15a-5p;hsa-miR-15b-3p;hsa-miR-17-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-24-2-5p;hsa-miR-374a-5p;hsa-miR-455-5p;hsa-miR-590-3p 11 BCL2 Sponge network 0.238 0.45396 -0.896 0 0.57
2 RP11-115D19.1 hsa-miR-15a-5p;hsa-miR-15b-3p;hsa-miR-17-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-24-2-5p;hsa-miR-374a-5p;hsa-miR-455-5p;hsa-miR-590-3p 12 BCL2 Sponge network -2.109 3.0E-5 -0.896 0 0.54
3 RP11-597D13.9 hsa-miR-15a-5p;hsa-miR-15b-3p;hsa-miR-17-5p;hsa-miR-181b-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-24-2-5p;hsa-miR-374a-5p;hsa-miR-455-5p;hsa-miR-590-3p;hsa-miR-590-5p 11 BCL2 Sponge network -0.884 3.0E-5 -0.896 0 0.538
4 RP11-81K13.1 hsa-miR-15a-5p;hsa-miR-15b-3p;hsa-miR-17-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-374a-5p;hsa-miR-455-5p;hsa-miR-590-3p;hsa-miR-590-5p 12 BCL2 Sponge network -2.81 2.0E-5 -0.896 0 0.405
5 RMST hsa-miR-15a-5p;hsa-miR-15b-3p;hsa-miR-17-5p;hsa-miR-181b-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-24-2-5p;hsa-miR-374a-5p;hsa-miR-590-3p 10 BCL2 Sponge network -2.444 0 -0.896 0 0.399
6 AC004947.2 hsa-miR-15a-5p;hsa-miR-15b-3p;hsa-miR-17-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-186-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-590-3p;hsa-miR-590-5p 10 BCL2 Sponge network -3.692 0 -0.896 0 0.373

Quest ID: acc0e42b3f2a4519a38858b9660fd063