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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-199b-5p AADAC -0.45 0.25461 -1.53 0 miRanda -0.16 4.0E-5 NA
2 hsa-miR-199b-5p AADAT -0.45 0.25461 -3.7 0 miRanda -0.15 0.00013 NA
3 hsa-miR-301a-3p ABCA1 0.84 0 -1.1 0 miRNATAP -0.13 0.00125 NA
4 hsa-miR-301a-3p ABCB7 0.84 0 -0.34 4.0E-5 MirTarget; miRNATAP -0.11 0 NA
5 hsa-let-7c-5p ABCB9 -1.71 0 1.01 0 MirTarget -0.27 0 NA
6 hsa-miR-195-5p ABCB9 -1.86 0 1.01 0 mirMAP -0.1 0.01229 NA
7 hsa-let-7c-5p ABCC10 -1.71 0 1.42 0 MirTarget -0.3 0 NA
8 hsa-miR-101-3p ABCC5 -1.48 0 1.23 0 MirTarget; miRNATAP -0.47 0 NA
9 hsa-miR-195-5p ABCC5 -1.86 0 1.23 0 MirTarget; miRNATAP -0.17 0 NA
10 hsa-miR-199b-5p ABCC6 -0.45 0.25461 -0.92 0 miRanda -0.1 1.0E-5 NA
11 hsa-miR-199a-5p ABCC6P2 -1.99 0 0.58 0.00027 miRanda -0.13 0 NA
12 hsa-miR-199b-5p ABCG2 -0.45 0.25461 -1.71 0 miRanda -0.19 0 NA
13 hsa-miR-301a-3p ABHD2 0.84 0 -1.2 0 mirMAP -0.38 0 NA
14 hsa-miR-199b-5p ABHD6 -0.45 0.25461 -1.31 0 miRanda -0.12 0 NA
15 hsa-miR-101-3p ABI2 -1.48 0 0.14 0.17339 miRNATAP -0.24 0 NA
16 hsa-miR-301a-3p ABTB2 0.84 0 -0.43 0.0031 mirMAP -0.21 0 NA
17 hsa-miR-101-3p ACBD3 -1.48 0 0.28 0.00131 miRNATAP -0.13 2.0E-5 NA
18 hsa-miR-301a-3p ACBD5 0.84 0 -0.75 0 MirTarget; miRNATAP -0.25 0 NA
19 hsa-miR-199b-5p ACOT13 -0.45 0.25461 -0.49 3.0E-5 miRanda -0.14 0 NA
20 hsa-miR-301a-3p ACSL1 0.84 0 -2.33 0 MirTarget; miRNATAP -0.56 0 NA
21 hsa-miR-101-3p ACSL4 -1.48 0 2.07 0 miRNATAP -0.89 0 NA
22 hsa-miR-195-5p ACSL4 -1.86 0 2.07 0 MirTarget; miRNATAP -0.44 0 NA
23 hsa-miR-199a-5p ACTN2 -1.99 0 1.96 2.0E-5 miRanda -0.23 0.00264 NA
24 hsa-miR-199b-5p ACTN2 -0.45 0.25461 1.96 2.0E-5 miRanda -0.19 0.00143 NA
25 hsa-miR-101-3p ADAMTS10 -1.48 0 0.73 0.00187 miRNATAP -0.28 0.00079 NA
26 hsa-miR-199a-5p ADCK5 -1.99 0 0.84 0 miRanda -0.11 0 NA
27 hsa-miR-301a-3p ADCY1 0.84 0 -2.7 0 MirTarget; miRNATAP -0.4 0.00018 NA
28 hsa-miR-101-3p ADCY6 -1.48 0 1.25 0 miRNATAP -0.34 0 NA
29 hsa-miR-199b-5p ADH4 -0.45 0.25461 -4.41 0 miRanda -0.19 0.00683 NA
30 hsa-miR-199a-5p ADH6 -1.99 0 -2.17 0 miRanda -0.11 0.02462 NA
31 hsa-miR-199b-5p ADH6 -0.45 0.25461 -2.17 0 miRanda -0.21 0 NA
32 hsa-miR-199b-5p ADHFE1 -0.45 0.25461 -1.33 0 miRanda -0.18 0 NA
33 hsa-miR-301a-3p AFF1 0.84 0 -0.71 0 MirTarget -0.16 0 NA
34 hsa-miR-101-3p AGAP1 -1.48 0 0.52 0 MirTarget -0.21 0 NA
35 hsa-miR-199a-5p AGBL5 -1.99 0 0.72 0 miRanda -0.13 0 NA
36 hsa-miR-101-3p AGFG1 -1.48 0 0.23 0.00166 MirTarget -0.12 0 NA
37 hsa-miR-199b-5p AGXT2 -0.45 0.25461 -2.89 0 miRanda -0.16 0.002 NA
38 hsa-miR-199b-5p AKAP6 -0.45 0.25461 -0.97 0 miRanda -0.11 0 NA
39 hsa-miR-199a-5p AKR1C2 -1.99 0 0.25 0.39842 miRanda -0.19 8.0E-5 NA
40 hsa-miR-199b-5p AKR1C2 -0.45 0.25461 0.25 0.39842 miRanda -0.16 2.0E-5 NA
41 hsa-miR-21-5p AKT2 1.51 0 -0.34 1.0E-5 miRNAWalker2 validate -0.25 0 NA
42 hsa-miR-330-5p AKT2 0.44 0.00533 -0.34 1.0E-5 miRanda -0.1 1.0E-5 NA
43 hsa-miR-342-3p AKT2 -0.32 0.04498 -0.34 1.0E-5 mirMAP -0.12 0 NA
44 hsa-miR-106b-5p AKT3 0.65 0 -0.66 0.00047 miRNATAP -0.26 0.00148 NA
45 hsa-miR-107 AKT3 0.24 0.01708 -0.66 0.00047 PITA; miRanda -0.6 0 NA
46 hsa-miR-122-5p AKT3 -1.24 0 -0.66 0.00047 miRNAWalker2 validate; miRTarBase -0.28 0 24244539 miR 122 regulates tumorigenesis in hepatocellular carcinoma by targeting AKT3; Here we identify AKT3 as a novel and direct target of miR-122; Restoration of miR-122 expression in HCC cell lines decreases AKT3 levels inhibits cell migration and proliferation and induces apoptosis; These anti-tumor phenotypes can be rescued by reconstitution of AKT3 expression indicating the essential role of AKT3 in miR-122 mediated HCC transformation; Our data strongly suggest that miR-122 is a tumor suppressor that targets AKT3 to regulate tumorigenesis in HCCs and a potential therapeutic candidate for liver cancer
47 hsa-miR-146b-5p AKT3 0.42 0.04574 -0.66 0.00047 miRNAWalker2 validate -0.16 0.00026 NA
48 hsa-miR-15a-5p AKT3 0.35 0.00077 -0.66 0.00047 miRNAWalker2 validate; miRTarBase; miRNATAP -0.27 0.00291 NA
49 hsa-miR-17-3p AKT3 0.41 0.00422 -0.66 0.00047 miRNATAP -0.35 0 NA
50 hsa-miR-17-5p AKT3 0.7 2.0E-5 -0.66 0.00047 TargetScan; miRNATAP -0.29 0 NA
51 hsa-miR-20a-5p AKT3 0.85 0 -0.66 0.00047 miRNATAP -0.29 0 NA
52 hsa-miR-32-3p AKT3 0.22 0.20722 -0.66 0.00047 mirMAP -0.23 4.0E-5 NA
53 hsa-miR-33a-3p AKT3 -0.68 1.0E-5 -0.66 0.00047 mirMAP -0.23 0.0001 NA
54 hsa-miR-362-3p AKT3 0.81 0 -0.66 0.00047 miRanda -0.22 0.00083 NA
55 hsa-miR-362-5p AKT3 0.72 2.0E-5 -0.66 0.00047 PITA; TargetScan; miRNATAP -0.15 0.00734 NA
56 hsa-miR-374a-5p AKT3 0.02 0.86978 -0.66 0.00047 mirMAP -0.28 0.00294 NA
57 hsa-miR-421 AKT3 0.94 0 -0.66 0.00047 miRanda; mirMAP -0.13 0.01091 NA
58 hsa-miR-501-3p AKT3 1 0 -0.66 0.00047 miRNATAP -0.12 0.04823 NA
59 hsa-miR-502-3p AKT3 0.66 0 -0.66 0.00047 miRNATAP -0.26 0.0008 NA
60 hsa-miR-616-5p AKT3 0.15 0.40284 -0.66 0.00047 mirMAP -0.2 0.0001 NA
61 hsa-miR-93-5p AKT3 1.4 0 -0.66 0.00047 miRNATAP -0.28 1.0E-5 NA
62 hsa-miR-199a-5p ALDH1L1 -1.99 0 -1.8 0 miRanda -0.21 0.00084 NA
63 hsa-miR-199b-5p ALDH1L1 -0.45 0.25461 -1.8 0 miRanda -0.33 0 NA
64 hsa-miR-301a-3p ALDH5A1 0.84 0 -1.1 0 mirMAP -0.41 0 NA
65 hsa-miR-199a-5p ALKBH2 -1.99 0 0.58 2.0E-5 miRanda -0.14 0 NA
66 hsa-miR-199b-5p ALKBH2 -0.45 0.25461 0.58 2.0E-5 miRanda -0.11 0 NA
67 hsa-miR-101-3p AMMECR1 -1.48 0 0.07 0.45093 miRNATAP -0.11 0.00172 NA
68 hsa-miR-301a-3p AMOTL1 0.84 0 -0.53 0.02603 mirMAP -0.16 0.01497 NA
69 hsa-miR-199a-5p ANKAR -1.99 0 0.96 0 miRanda -0.12 0 NA
70 hsa-miR-195-5p ANKRD13D -1.86 0 0.79 0 MirTarget -0.11 0.00036 NA
71 hsa-miR-199a-5p ANKRD26P1 -1.99 0 0.43 0.21485 miRanda -0.16 0.00457 NA
72 hsa-miR-101-3p ANKRD27 -1.48 0 0.9 0 mirMAP -0.33 0 NA
73 hsa-let-7c-5p ANKRD49 -1.71 0 0.4 0 MirTarget -0.1 0 NA
74 hsa-miR-101-3p ANKRD52 -1.48 0 1.46 0 miRNATAP -0.5 0 NA
75 hsa-miR-199a-3p ANKRD52 -2.33 0 1.46 0 PITA; miRNATAP -0.11 0 NA
76 hsa-miR-101-3p ANKZF1 -1.48 0 0.85 0 MirTarget -0.19 0 NA
77 hsa-miR-301a-3p AP1G1 0.84 0 -0.48 0 miRNATAP -0.19 0 NA
78 hsa-miR-101-3p AP1S3 -1.48 0 0.35 0.01747 miRNAWalker2 validate -0.28 0 NA
79 hsa-miR-199a-3p AP3B1 -2.33 0 0.63 0 PITA -0.1 0 NA
80 hsa-miR-301a-3p AP3S2 0.84 0 -0.33 4.0E-5 mirMAP -0.17 0 NA
81 hsa-miR-301a-3p APBB2 0.84 0 -0.24 0.03085 mirMAP -0.13 1.0E-5 NA
82 hsa-miR-199a-5p APC2 -1.99 0 1.72 0 mirMAP -0.1 0.00178 NA
83 hsa-miR-195-5p APLN -1.86 0 3.69 0 MirTarget; miRNATAP -0.63 0 NA
84 hsa-miR-199b-5p APOC1 -0.45 0.25461 -0.97 6.0E-5 miRanda -0.16 0 NA
85 hsa-miR-199b-5p AQP11 -0.45 0.25461 -0.63 0.00064 miRNATAP -0.13 0 NA
86 hsa-miR-301a-3p AR 0.84 0 -2.66 0 mirMAP; miRNATAP -1.06 0 25940439 Mechanism dissection revealed infiltrating pre-adipocytes might function through down-regulation of the androgen receptor AR via modulation of miR-301a and then increase PCa cell invasion via induction of TGF-β1/Smad/MMP9 signals
87 hsa-miR-195-5p ARFGAP1 -1.86 0 0.64 0 mirMAP -0.15 0 NA
88 hsa-miR-301a-3p ARFIP1 0.84 0 -0.21 0.00812 miRNATAP -0.12 0 NA
89 hsa-miR-301a-3p ARHGEF12 0.84 0 -0.86 0 MirTarget; miRNATAP -0.23 0 NA
90 hsa-miR-101-3p ARHGEF3 -1.48 0 0.51 0.00381 MirTarget -0.41 0 NA
91 hsa-miR-195-5p ARL2 -1.86 0 0.82 0 MirTarget; miRNATAP -0.15 1.0E-5 NA
92 hsa-miR-301a-3p ARL6IP1 0.84 0 -0.85 0 MirTarget -0.14 0 NA
93 hsa-miR-301a-3p ARMC5 0.84 0 -0.65 1.0E-5 mirMAP -0.27 0 NA
94 hsa-miR-101-3p ARNTL2 -1.48 0 0.02 0.94112 MirTarget -0.42 0.0001 NA
95 hsa-miR-301a-3p ARRDC3 0.84 0 -0.7 0 miRNATAP -0.11 0.00797 NA
96 hsa-miR-301a-3p ART4 0.84 0 -1.74 0 mirMAP -0.42 0 NA
97 hsa-miR-101-3p ASAP1 -1.48 0 0.6 1.0E-5 MirTarget; miRNATAP -0.42 0 NA
98 hsa-miR-199a-5p ASB4 -1.99 0 -0.62 0.06683 miRanda -0.17 0.0018 NA
99 hsa-miR-199b-5p ASB4 -0.45 0.25461 -0.62 0.06683 miRanda -0.22 0 NA
100 hsa-miR-301a-3p ASPA 0.84 0 -2.88 0 mirMAP -0.46 0 NA
101 hsa-miR-301a-3p ASXL2 0.84 0 -0.29 0.18051 MirTarget; miRNATAP -0.15 0.01157 NA
102 hsa-miR-301a-3p ASXL3 0.84 0 -2.69 0 mirMAP -0.64 0 NA
103 hsa-miR-301a-3p ATF6 0.84 0 -0.02 0.87055 mirMAP -0.15 0 NA
104 hsa-miR-101-3p ATG4D -1.48 0 0.24 0.03588 miRTarBase -0.13 0.00104 NA
105 hsa-miR-199a-5p ATOX1 -1.99 0 0.43 0.00496 mirMAP -0.11 0 NA
106 hsa-miR-199b-5p ATOX1 -0.45 0.25461 0.43 0.00496 mirMAP -0.11 0 NA
107 hsa-miR-101-3p ATP1B1 -1.48 0 0.44 0.00298 miRNATAP -0.21 7.0E-5 NA
108 hsa-miR-101-3p ATP2B1 -1.48 0 -0.16 0.1608 miRNATAP -0.12 0.00303 NA
109 hsa-miR-101-3p ATP5G2 -1.48 0 0.3 0.00093 miRNATAP -0.15 0 NA
110 hsa-miR-301a-3p ATXN7L1 0.84 0 -0.24 0.06065 miRNATAP -0.27 0 NA
111 hsa-miR-195-5p ATXN7L2 -1.86 0 1.07 0 MirTarget; miRNATAP -0.21 0 NA
112 hsa-miR-195-5p ATXN7L3 -1.86 0 0.7 0 MirTarget; miRNATAP -0.16 0 NA
113 hsa-miR-195-5p AVL9 -1.86 0 0.36 0.00032 MirTarget; miRNATAP -0.13 0 NA
114 hsa-miR-195-5p AXIN2 -1.86 0 0.11 0.75298 MirTarget; miRNATAP -0.25 0.00506 NA
115 hsa-miR-101-3p B3GALNT2 -1.48 0 0.86 0 MirTarget -0.25 0 NA
116 hsa-miR-101-3p B3GNT3 -1.48 0 0.22 0.62814 MirTarget -1.39 0 NA
117 hsa-miR-199a-5p BAAT -1.99 0 -1.22 1.0E-5 PITA; miRanda -0.12 0.00643 NA
118 hsa-miR-199b-5p BAAT -0.45 0.25461 -1.22 1.0E-5 PITA; miRanda -0.19 0 NA
119 hsa-miR-301a-3p BACH2 0.84 0 -1.99 0 mirMAP; miRNATAP -0.29 4.0E-5 NA
120 hsa-miR-101-3p BAZ2A -1.48 0 0.46 0 MirTarget; miRNATAP -0.19 0 NA
121 hsa-miR-101-3p BBC3 -1.48 0 0.8 0 miRNATAP -0.32 0 NA
122 hsa-miR-101-3p BCL9 -1.48 0 1.18 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.42 0 NA
123 hsa-miR-101-3p BEGAIN -1.48 0 -0.42 0.21738 MirTarget -0.25 0.03932 NA
124 hsa-miR-199b-5p BHMT -0.45 0.25461 -3.29 0 miRanda -0.35 0 NA
125 hsa-miR-101-3p BIRC5 -1.48 0 4.5 0 miRNAWalker2 validate -1.33 0 NA
126 hsa-miR-199b-5p BLCAP -0.45 0.25461 -0.41 0.00021 PITA; miRanda; miRNATAP -0.1 0 NA
127 hsa-miR-301a-3p BLCAP 0.84 0 -0.41 0.00021 MirTarget; miRNATAP -0.17 0 NA
128 hsa-miR-301a-3p BMP6 0.84 0 -1.04 0 MirTarget -0.14 0.01206 NA
129 hsa-miR-301a-3p BMPR2 0.84 0 -0.74 0 MirTarget; miRNATAP -0.11 0.00019 NA
130 hsa-miR-199a-5p BRCA1 -1.99 0 0.89 0 miRanda -0.14 0 NA
131 hsa-miR-195-5p BRPF3 -1.86 0 0.35 0.00299 miRNATAP -0.15 0 NA
132 hsa-miR-195-5p BSG -1.86 0 0.9 0 mirMAP -0.14 0 NA
133 hsa-miR-199a-5p BSN -1.99 0 0.94 2.0E-5 miRanda -0.14 9.0E-5 NA
134 hsa-miR-101-3p BTBD3 -1.48 0 0.3 0.00861 miRNATAP -0.16 0.0001 NA
135 hsa-miR-101-3p BTG2 -1.48 0 -0.63 0.00028 miRNAWalker2 validate -0.14 0.0208 NA
136 hsa-miR-199a-5p BTNL9 -1.99 0 0.27 0.25012 miRanda -0.11 0.00436 NA
137 hsa-miR-199b-5p BTNL9 -0.45 0.25461 0.27 0.25012 miRanda -0.19 0 NA
138 hsa-miR-199a-5p BUB1 -1.99 0 4.05 0 miRanda -0.29 0 NA
139 hsa-let-7c-5p BZW2 -1.71 0 0.58 0 MirTarget -0.2 0 NA
140 hsa-miR-301a-3p C16orf70 0.84 0 -0.77 0 miRNATAP -0.24 0 NA
141 hsa-miR-301a-3p C17orf51 0.84 0 -0.67 0.00164 mirMAP -0.24 4.0E-5 NA
142 hsa-miR-301a-3p C1S 0.84 0 -1.68 0 MirTarget -0.58 0 NA
143 hsa-miR-199a-5p C1orf105 -1.99 0 0.82 0.00234 miRNATAP -0.2 0 NA
144 hsa-miR-199b-5p C1orf105 -0.45 0.25461 0.82 0.00234 miRNATAP -0.15 1.0E-5 NA
145 hsa-miR-301a-3p C5 0.84 0 -1.23 0 MirTarget -0.31 0 NA
146 hsa-miR-195-5p C6orf223 -1.86 0 0.67 0.18925 mirMAP -0.36 0.00378 NA
147 hsa-miR-199a-3p C9orf40 -2.33 0 0.6 0 miRNATAP -0.13 0 NA
148 hsa-miR-101-3p CA12 -1.48 0 2.34 0 mirMAP -1.22 0 NA
149 hsa-miR-199a-5p CA4 -1.99 0 1.36 0.00143 miRanda -0.42 0 NA
150 hsa-miR-15a-5p CAB39 0.35 0.00077 -0.15 0.00963 miRNATAP -0.11 8.0E-5 NA
NumGOOverlapSizeP ValueAdj. P Value
1 INTRACELLULAR SIGNAL TRANSDUCTION 138 1572 4.531e-11 2.108e-07
2 CELL CYCLE 120 1316 9.565e-11 2.225e-07
3 REGULATION OF CELL CYCLE 94 949 1.799e-10 2.79e-07
4 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 128 1517 3.081e-09 2.99e-06
5 NEUROGENESIS 120 1402 4.478e-09 2.99e-06
6 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 71 684 5.004e-09 2.99e-06
7 NEGATIVE REGULATION OF CELL CYCLE 52 433 5.14e-09 2.99e-06
8 CELL CYCLE PROCESS 99 1081 3.943e-09 2.99e-06
9 NEGATIVE REGULATION OF CELL CYCLE PROCESS 33 214 8.687e-09 4.491e-06
10 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 142 1805 3.507e-08 1.487e-05
11 REGULATION OF CELL SIZE 28 172 3.514e-08 1.487e-05
12 NEGATIVE REGULATION OF GENE EXPRESSION 122 1493 4.724e-08 1.618e-05
13 MITOTIC CELL CYCLE 74 766 4.868e-08 1.618e-05
14 CELLULAR RESPONSE TO OXYGEN LEVELS 25 143 4.463e-08 1.618e-05
15 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 90 1004 5.728e-08 1.777e-05
16 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 90 1008 6.871e-08 1.998e-05
17 REGULATION OF CELL GROWTH 46 391 7.36e-08 2.014e-05
18 POSITIVE REGULATION OF GENE EXPRESSION 136 1733 8.275e-08 2.017e-05
19 CELLULAR RESPONSE TO HORMONE STIMULUS 58 552 8.669e-08 2.017e-05
20 REGULATION OF CELL DIFFERENTIATION 121 1492 8.182e-08 2.017e-05
21 GLYCEROLIPID METABOLIC PROCESS 43 356 9.289e-08 2.058e-05
22 REGULATION OF NEURON DIFFERENTIATION 58 554 9.82e-08 2.077e-05
23 REGULATION OF MITOTIC CELL CYCLE 51 468 1.702e-07 3.443e-05
24 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 149 1977 2.242e-07 4.346e-05
25 REGULATION OF NEURON PROJECTION DEVELOPMENT 46 408 2.581e-07 4.479e-05
26 CENTRAL NERVOUS SYSTEM DEVELOPMENT 79 872 2.518e-07 4.479e-05
27 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 137 1784 2.599e-07 4.479e-05
28 EMBRYO DEVELOPMENT 80 894 3.488e-07 5.649e-05
29 TOR SIGNALING 8 16 3.521e-07 5.649e-05
30 REGULATION OF CELL PROJECTION ORGANIZATION 56 558 6.489e-07 0.0001006
31 REGULATION OF CELL DEVELOPMENT 75 836 7.462e-07 0.000112
32 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 128 1672 8.026e-07 0.0001132
33 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 28 199 7.924e-07 0.0001132
34 REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 14 59 9.439e-07 0.0001292
35 PHOSPHORYLATION 100 1228 1.009e-06 0.0001341
36 RESPONSE TO OXYGEN LEVELS 37 311 1.05e-06 0.0001358
37 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 52 513 1.21e-06 0.0001521
38 RESPONSE TO INSULIN 28 205 1.451e-06 0.0001714
39 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 86 1021 1.584e-06 0.0001714
40 CONNECTIVE TISSUE DEVELOPMENT 27 194 1.539e-06 0.0001714
41 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 41 368 1.559e-06 0.0001714
42 REGULATION OF CELL CYCLE PROCESS 55 558 1.431e-06 0.0001714
43 CELL CYCLE CHECKPOINT 27 194 1.539e-06 0.0001714
44 REGULATION OF ORGANELLE ORGANIZATION 96 1178 1.632e-06 0.0001726
45 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 68 750 1.72e-06 0.0001749
46 REGULATION OF GROWTH 60 633 1.729e-06 0.0001749
47 RESPONSE TO ABIOTIC STIMULUS 86 1024 1.784e-06 0.0001766
48 CELL DEVELOPMENT 111 1426 2.17e-06 0.0002103
49 NEGATIVE REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 21 131 2.279e-06 0.0002145
50 NEGATIVE REGULATION OF ORGANELLE ORGANIZATION 42 387 2.305e-06 0.0002145
51 LIPID BIOSYNTHETIC PROCESS 53 539 2.385e-06 0.0002176
52 REGULATION OF EXTENT OF CELL GROWTH 18 101 2.532e-06 0.0002265
53 REGULATION OF AXONOGENESIS 24 168 3.645e-06 0.00032
54 CELLULAR RESPONSE TO INSULIN STIMULUS 22 146 3.786e-06 0.0003203
55 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 22 146 3.786e-06 0.0003203
56 LIPID METABOLIC PROCESS 93 1158 4.394e-06 0.0003651
57 NEGATIVE REGULATION OF CELL GROWTH 24 170 4.495e-06 0.0003669
58 PROTEIN PHOSPHORYLATION 79 944 5.443e-06 0.0004367
59 CELL PROLIFERATION 61 672 5.689e-06 0.0004487
60 NEURON PROJECTION MORPHOGENESIS 42 402 6.03e-06 0.0004677
61 ORGAN MORPHOGENESIS 72 841 6.599e-06 0.0005033
62 REGULATION OF GLUCOSE IMPORT 13 60 6.81e-06 0.0005111
63 NEURON PROJECTION DEVELOPMENT 52 545 7.035e-06 0.0005196
64 NEURON DIFFERENTIATION 74 874 7.246e-06 0.0005268
65 NEGATIVE REGULATION OF GROWTH 29 236 8.032e-06 0.000575
66 CELLULAR RESPONSE TO NITROGEN COMPOUND 49 505 8.203e-06 0.0005783
67 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 22 154 9.157e-06 0.0006327
68 PROTEIN LOCALIZATION 131 1805 9.247e-06 0.0006327
69 CELLULAR LIPID METABOLIC PROCESS 76 913 9.945e-06 0.0006706
70 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 25 191 1.116e-05 0.0007419
71 SKELETAL SYSTEM DEVELOPMENT 45 455 1.178e-05 0.000772
72 REGULATION OF CHEMOTAXIS 24 180 1.213e-05 0.0007779
73 POSITIVE REGULATION OF CELL CYCLE 36 332 1.22e-05 0.0007779
74 RESPONSE TO ENDOGENOUS STIMULUS 109 1450 1.282e-05 0.000806
75 REGULATION OF POSITIVE CHEMOTAXIS 8 24 1.404e-05 0.0008614
76 REGULATION OF CELL CYCLE PHASE TRANSITION 35 321 1.426e-05 0.0008614
77 REGULATION OF TRANSPORT 130 1804 1.417e-05 0.0008614
78 CARTILAGE DEVELOPMENT 21 147 1.453e-05 0.0008665
79 RESPONSE TO HORMONE 74 893 1.521e-05 0.000896
80 RESPONSE TO PEPTIDE 41 404 1.558e-05 0.0009061
81 REGULATION OF AXON GUIDANCE 10 39 1.63e-05 0.0009366
82 GLAND DEVELOPMENT 40 395 2.072e-05 0.001176
83 CELL PROJECTION ORGANIZATION 74 902 2.134e-05 0.001196
84 TISSUE DEVELOPMENT 112 1518 2.185e-05 0.001211
85 GLYCEROLIPID BIOSYNTHETIC PROCESS 26 211 2.214e-05 0.001212
86 REGULATION OF DEVELOPMENTAL GROWTH 32 289 2.415e-05 0.001291
87 REGULATION OF DNA TEMPLATED TRANSCRIPTION IN RESPONSE TO STRESS 13 67 2.414e-05 0.001291
88 POSITIVE REGULATION OF MOLECULAR FUNCTION 128 1791 2.452e-05 0.001296
89 PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROCESS 18 120 3.001e-05 0.001569
90 SMALL MOLECULE METABOLIC PROCESS 126 1767 3.167e-05 0.001638
91 NEGATIVE REGULATION OF GLUCOSE IMPORT 6 14 3.343e-05 0.001709
92 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 20 144 3.492e-05 0.001766
93 REGULATION OF LIPID METABOLIC PROCESS 31 282 3.699e-05 0.001851
94 PHOSPHOLIPID METABOLIC PROCESS 37 364 3.856e-05 0.001889
95 REGULATION OF CATABOLIC PROCESS 62 731 3.817e-05 0.001889
96 REGULATION OF CELLULAR COMPONENT SIZE 35 337 3.981e-05 0.001929
97 NEURON DEVELOPMENT 59 687 4.122e-05 0.001966
98 GLYCEROPHOSPHOLIPID METABOLIC PROCESS 32 297 4.14e-05 0.001966
99 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 44 465 4.293e-05 0.002018
100 RESPONSE TO NITROGEN COMPOUND 70 859 4.41e-05 0.002052
101 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 50 554 4.561e-05 0.002076
102 CHROMATIN MODIFICATION 49 539 4.515e-05 0.002076
103 POSITIVE REGULATION OF CATABOLIC PROCESS 39 395 4.596e-05 0.002076
104 GROWTH 40 410 4.822e-05 0.002157
105 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 61 724 5.33e-05 0.00234
106 CELLULAR RESPONSE TO PEPTIDE 30 274 5.288e-05 0.00234
107 REGULATION OF NUCLEOTIDE CATABOLIC PROCESS 9 36 5.385e-05 0.002342
108 POSITIVE REGULATION OF CATALYTIC ACTIVITY 110 1518 5.502e-05 0.00237
109 ENDOCHONDRAL BONE MORPHOGENESIS 10 45 6.22e-05 0.002655
110 ESTABLISHMENT OF PROTEIN LOCALIZATION 104 1423 6.38e-05 0.002699
111 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 95 1275 6.646e-05 0.002786
112 MITOTIC CELL CYCLE CHECKPOINT 19 139 6.776e-05 0.002815
113 POSTTRANSCRIPTIONAL REGULATION OF GENE EXPRESSION 42 448 7.842e-05 0.003229
114 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 80 1036 8.029e-05 0.003249
115 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 80 1036 8.029e-05 0.003249
116 SENSORY ORGAN DEVELOPMENT 45 493 8.306e-05 0.003275
117 NEGATIVE REGULATION OF AXONOGENESIS 12 65 8.217e-05 0.003275
118 REGULATION OF PHOSPHORUS METABOLIC PROCESS 115 1618 8.279e-05 0.003275
119 NEGATIVE REGULATION OF TOR SIGNALING 8 30 8.537e-05 0.003338
120 REGULATION OF OSSIFICATION 22 178 8.828e-05 0.003423
121 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 34 337 9.072e-05 0.003488
122 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 117 1656 9.162e-05 0.003488
123 RESPONSE TO NUTRIENT 23 191 9.221e-05 0.003488
124 REGULATION OF CELL DEATH 106 1472 9.68e-05 0.003632
125 POSITIVE REGULATION OF KINASE ACTIVITY 44 482 9.903e-05 0.003659
126 HEAD DEVELOPMENT 59 709 9.909e-05 0.003659
127 NEURON PROJECTION GUIDANCE 24 205 0.0001024 0.003751
128 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 86 1142 0.0001036 0.003768
129 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 107 1492 0.0001051 0.003792
130 REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 35 354 0.0001077 0.003856
131 REGULATION OF EPITHELIAL CELL PROLIFERATION 30 285 0.0001086 0.003857
132 RESPONSE TO EXTRACELLULAR STIMULUS 41 441 0.000114 0.004018
133 NEGATIVE REGULATION OF GLUCOSE TRANSPORT 6 17 0.000121 0.004232
134 REGULATION OF ANATOMICAL STRUCTURE SIZE 43 472 0.0001238 0.004298
135 POSITIVE REGULATION OF CELL CYCLE PROCESS 27 247 0.0001261 0.004347
136 ENDOCRINE PANCREAS DEVELOPMENT 9 40 0.0001305 0.004432
137 CELL CYCLE G1 S PHASE TRANSITION 16 111 0.0001324 0.004432
138 G1 S TRANSITION OF MITOTIC CELL CYCLE 16 111 0.0001324 0.004432
139 DNA INTEGRITY CHECKPOINT 19 146 0.0001321 0.004432
140 NEGATIVE REGULATION OF CELL DEVELOPMENT 31 303 0.0001415 0.00445
141 CELL DIVISION 42 460 0.0001408 0.00445
142 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 28 262 0.0001405 0.00445
143 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 86 1152 0.0001392 0.00445
144 PHOSPHOLIPID BIOSYNTHETIC PROCESS 26 235 0.0001373 0.00445
145 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO HYPOXIA 8 32 0.0001403 0.00445
146 MITOTIC DNA INTEGRITY CHECKPOINT 15 100 0.0001351 0.00445
147 REGULATION OF GLUCOSE TRANSPORT 15 100 0.0001351 0.00445
148 STEROL METABOLIC PROCESS 17 123 0.0001401 0.00445
149 INOSITOL LIPID MEDIATED SIGNALING 17 124 0.000155 0.004839
150 REGULATION OF CELL MORPHOGENESIS 48 552 0.0001575 0.004884
151 CHROMOSOME ORGANIZATION 77 1009 0.0001585 0.004885
152 DEVELOPMENTAL GROWTH 33 333 0.0001604 0.004911
153 NEGATIVE REGULATION OF LIPID METABOLIC PROCESS 13 80 0.000164 0.004988
154 PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 7 25 0.0001704 0.005149
155 CELL MOTILITY 66 835 0.0001758 0.005211
156 LOCALIZATION OF CELL 66 835 0.0001758 0.005211
157 RESPONSE TO CAFFEINE 6 18 0.0001738 0.005211
158 REGULATION OF CELLULAR LOCALIZATION 93 1277 0.0001787 0.005264
159 CELLULAR COMPONENT MORPHOGENESIS 70 900 0.0001814 0.005308
160 CELL PART MORPHOGENESIS 53 633 0.00019 0.005524
161 LOCOMOTION 83 1114 0.000194 0.005607
162 SKELETAL SYSTEM MORPHOGENESIS 23 201 0.0001991 0.005719
163 CELLULAR RESPONSE TO ALCOHOL 16 115 0.0002016 0.005755
164 REGULATION OF KINASE ACTIVITY 62 776 0.0002058 0.005838
165 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 15 104 0.000211 0.005951
166 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 25 229 0.0002254 0.006206
167 ESTABLISHMENT OF LOCALIZATION IN CELL 116 1676 0.0002244 0.006206
168 PROTEIN KINASE B SIGNALING 8 34 0.0002215 0.006206
169 REGULATION OF LIPID CATABOLIC PROCESS 10 52 0.0002243 0.006206
170 CELLULAR RESPONSE TO LIPID 41 457 0.0002436 0.006667
171 REGULATION OF CYTOSKELETON ORGANIZATION 44 502 0.0002453 0.006676
172 REGULATION OF EPITHELIAL CELL MIGRATION 20 166 0.0002563 0.006933
173 CELLULAR RESPONSE TO KETONE 12 73 0.0002594 0.006977
174 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 63 799 0.0002624 0.006994
175 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 24 218 0.000263 0.006994
176 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 13 84 0.0002707 0.007156
177 FOREBRAIN DEVELOPMENT 34 357 0.0002724 0.00716
178 POSITIVE REGULATION OF CELL COMMUNICATION 107 1532 0.0002859 0.007473
179 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 7 27 0.0002883 0.007495
180 NEGATIVE REGULATION OF CHROMOSOME ORGANIZATION 14 96 0.000302 0.007806
181 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 59 740 0.0003074 0.007902
182 EMBRYONIC MORPHOGENESIS 46 539 0.0003252 0.008314
183 CHROMATIN ORGANIZATION 54 663 0.0003279 0.008337
184 EAR DEVELOPMENT 22 195 0.0003314 0.00838
185 SPROUTING ANGIOGENESIS 9 45 0.0003377 0.008448
186 REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 8 36 0.0003377 0.008448
187 ORGANOPHOSPHATE BIOSYNTHETIC PROCESS 40 450 0.0003481 0.008662
188 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 83 1135 0.0003509 0.008685
189 EPIDERMAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 10 55 0.0003618 0.008908
190 REGULATION OF CHROMOSOME ORGANIZATION 28 278 0.0003761 0.00921
191 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 72 957 0.0003891 0.009332
192 VESICLE MEDIATED TRANSPORT 89 1239 0.000387 0.009332
193 REGULATION OF FATTY ACID METABOLIC PROCESS 13 87 0.0003853 0.009332
194 BLOOD VESSEL MORPHOGENESIS 34 364 0.0003891 0.009332
195 EMBRYONIC ORGAN MORPHOGENESIS 28 279 0.0003985 0.009463
196 ANGIOGENESIS 29 293 0.0003986 0.009463
197 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 96 1360 0.0004153 0.009808
NumGOOverlapSizeP ValueAdj. P Value
1 ENZYME BINDING 142 1737 3.041e-09 2.825e-06
2 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 40 315 6.719e-08 3.121e-05
3 RIBONUCLEOTIDE BINDING 143 1860 1.269e-07 3.929e-05
4 KINASE ACTIVITY 77 842 2.475e-07 4.598e-05
5 PROTEIN SERINE THREONINE KINASE ACTIVITY 49 445 2.17e-07 4.598e-05
6 ADENYL NUCLEOTIDE BINDING 120 1514 3.16e-07 4.893e-05
7 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 30 226 1.138e-06 0.0001511
8 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 38 328 1.453e-06 0.0001687
9 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 84 992 1.708e-06 0.0001763
10 REGULATORY REGION NUCLEIC ACID BINDING 72 818 2.49e-06 0.0002314
11 GTPASE BINDING 33 295 1.467e-05 0.001239
12 DOUBLE STRANDED DNA BINDING 65 764 2.259e-05 0.001749
13 SEQUENCE SPECIFIC DNA BINDING 82 1037 2.879e-05 0.002057
14 TRANSLATION REGULATOR ACTIVITY 9 35 4.226e-05 0.002804
15 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 55 629 4.609e-05 0.002842
16 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 91 1199 4.894e-05 0.002842
17 PROTEIN KINASE ACTIVITY 55 640 7.335e-05 0.004008
18 PHOSPHATIDYLINOSITOL PHOSPHATE KINASE ACTIVITY 6 16 8.175e-05 0.004219
19 IDENTICAL PROTEIN BINDING 89 1209 0.0001719 0.008407
20 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 50 588 0.0001985 0.009221
21 CORE PROMOTER BINDING 19 152 0.000225 0.009952
NumGOOverlapSizeP ValueAdj. P Value
1 PHOSPHATIDYLINOSITOL 3 KINASE COMPLEX 9 20 1.987e-07 0.0001161

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 mTOR_signaling_pathway_hsa04150 39 151 9.981e-18 5.19e-16
2 AMPK_signaling_pathway_hsa04152 29 121 1.226e-12 3.187e-11
3 Cellular_senescence_hsa04218 29 160 1.597e-09 2.768e-08
4 Autophagy_animal_hsa04140 24 128 2.038e-08 2.488e-07
5 PI3K_Akt_signaling_pathway_hsa04151 44 352 2.393e-08 2.488e-07
6 HIF_1_signaling_pathway_hsa04066 20 100 1.002e-07 8.683e-07
7 FoxO_signaling_pathway_hsa04068 23 132 1.631e-07 1.212e-06
8 Phosphatidylinositol_signaling_system_hsa04070 19 99 4.098e-07 2.664e-06
9 Focal_adhesion_hsa04510 27 199 2.531e-06 1.462e-05
10 VEGF_signaling_pathway_hsa04370 13 59 5.589e-06 2.596e-05
11 p53_signaling_pathway_hsa04115 14 68 5.737e-06 2.596e-05
12 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 21 139 5.992e-06 2.596e-05
13 ErbB_signaling_pathway_hsa04012 15 85 1.934e-05 7.738e-05
14 Phospholipase_D_signaling_pathway_hsa04072 20 146 4.269e-05 0.0001586
15 Rap1_signaling_pathway_hsa04015 23 206 0.0002856 0.00099
16 Regulation_of_actin_cytoskeleton_hsa04810 23 208 0.0003285 0.001068
17 cAMP_signaling_pathway_hsa04024 21 198 0.001007 0.003081
18 Cell_cycle_hsa04110 15 124 0.001392 0.003904
19 Apelin_signaling_pathway_hsa04371 16 137 0.001427 0.003904
20 Apoptosis_hsa04210 16 138 0.00154 0.004005
21 Ras_signaling_pathway_hsa04014 22 232 0.003231 0.008001
22 Oocyte_meiosis_hsa04114 14 124 0.003763 0.008894
23 Hippo_signaling_pathway_hsa04390 16 154 0.004674 0.01057
24 ABC_transporters_hsa02010 7 45 0.00672 0.01456
25 TNF_signaling_pathway_hsa04668 11 108 0.01973 0.04104
26 Tight_junction_hsa04530 15 170 0.02437 0.04873
27 Sphingolipid_signaling_pathway_hsa04071 11 118 0.03505 0.06548
28 cGMP_PKG_signaling_pathway_hsa04022 14 163 0.03526 0.06548
29 Hippo_signaling_pathway_multiple_species_hsa04392 4 29 0.05528 0.09913
30 TGF_beta_signaling_pathway_hsa04350 8 84 0.05975 0.1036
31 Endocytosis_hsa04144 17 244 0.1083 0.1817
32 ECM_receptor_interaction_hsa04512 7 82 0.1173 0.1906
33 Peroxisome_hsa04146 7 83 0.1229 0.1937
34 Adherens_junction_hsa04520 6 72 0.1525 0.2332
35 MAPK_signaling_pathway_hsa04010 19 295 0.16 0.2378
36 Lysosome_hsa04142 9 123 0.1655 0.239
37 Jak_STAT_signaling_pathway_hsa04630 10 162 0.2966 0.4168
38 Ferroptosis_hsa04216 3 40 0.3255 0.4454
39 Mitophagy_animal_hsa04137 4 65 0.413 0.5507
40 Cell_adhesion_molecules_.CAMs._hsa04514 8 145 0.444 0.5626
41 Wnt_signaling_pathway_hsa04310 8 146 0.4516 0.5626
42 Gap_junction_hsa04540 5 88 0.4544 0.5626
43 Autophagy_other_hsa04136 2 32 0.4823 0.5833
44 Apoptosis_multiple_species_hsa04215 2 33 0.4987 0.5893
45 Calcium_signaling_pathway_hsa04020 9 182 0.5666 0.6548
46 Notch_signaling_pathway_hsa04330 2 48 0.7018 0.7841
47 NF_kappa_B_signaling_pathway_hsa04064 4 95 0.7087 0.7841
48 Phagosome_hsa04145 4 152 0.9505 0.9865
49 Cytokine_cytokine_receptor_interaction_hsa04060 8 270 0.9642 0.9865
50 Necroptosis_hsa04217 4 164 0.9675 0.9865

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1

HCG11

hsa-miR-106b-5p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-33a-3p;hsa-miR-362-3p;hsa-miR-421;hsa-miR-501-3p;hsa-miR-502-3p;hsa-miR-93-5p 12 AKT3 Sponge network -0.781 0 -0.659 0.00047 0.574
2 DHRS4-AS1 hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-582-5p;hsa-miR-589-3p 10 PIK3R1 Sponge network -0.646 0.01829 -0.892 0 0.557
3 DNM3OS hsa-miR-106b-5p;hsa-miR-107;hsa-miR-122-5p;hsa-miR-15a-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-32-3p;hsa-miR-502-3p;hsa-miR-616-5p;hsa-miR-93-5p 11 AKT3 Sponge network -2.094 1.0E-5 -0.659 0.00047 0.541
4 RP11-434D9.1 hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-409-3p;hsa-miR-629-3p 13 PIK3R1 Sponge network -2.913 0 -0.892 0 0.525
5

RP11-290F5.1

hsa-miR-103a-2-5p;hsa-miR-15b-3p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-181c-5p;hsa-miR-301a-3p;hsa-miR-3913-5p;hsa-miR-421;hsa-miR-485-3p;hsa-miR-940 10 IGF1 Sponge network -1.679 5.0E-5 -3.091 0 0.523
6 LINC00261 hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-15b-5p;hsa-miR-188-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-324-3p;hsa-miR-330-3p;hsa-miR-589-3p;hsa-miR-629-3p 13 PIK3R1 Sponge network -1.194 0 -0.892 0 0.513
7 RP11-513G11.3 hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-93-5p 10 PIK3R1 Sponge network -2.342 5.0E-5 -0.892 0 0.492
8 RP11-12A2.3 hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-188-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-93-5p 14 PIK3R1 Sponge network -4.779 0 -0.892 0 0.489
9 LINC01018 hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-188-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-324-3p;hsa-miR-338-5p;hsa-miR-409-3p;hsa-miR-589-3p;hsa-miR-629-3p;hsa-miR-93-5p 18 PIK3R1 Sponge network -3.231 0 -0.892 0 0.472
10 LDLRAD4-AS1 hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-188-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-589-3p;hsa-miR-93-5p 13 PIK3R1 Sponge network -3.366 0 -0.892 0 0.45
11 RP11-119D9.1 hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-188-5p;hsa-miR-200c-3p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-629-3p;hsa-miR-93-5p 11 PIK3R1 Sponge network -2.765 0 -0.892 0 0.418
12 LINC01057 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-130b-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-26a-5p 10 PRKAA2 Sponge network 1.427 3.0E-5 0.91 0.01333 0.409
13

RP11-290F5.1

hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-188-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-324-3p;hsa-miR-493-5p 13 PIK3R1 Sponge network -1.679 5.0E-5 -0.892 0 0.402
14 RP11-115J16.1 hsa-miR-103a-3p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-185-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-324-3p;hsa-miR-338-5p;hsa-miR-589-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -2.038 7.0E-5 -0.892 0 0.382
15 LINC00238 hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-188-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-629-3p 12 PIK3R1 Sponge network -4.997 0 -0.892 0 0.369
16

MAGI2-AS3

hsa-miR-17-5p;hsa-miR-192-3p;hsa-miR-193a-3p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-30d-5p;hsa-miR-3127-5p;hsa-miR-532-3p;hsa-miR-589-5p;hsa-miR-93-3p 10 RPS6KA2 Sponge network -1.801 0 -0.43 0.0094 0.363
17 AC004862.6 hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-188-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-589-3p;hsa-miR-629-3p;hsa-miR-93-5p 13 PIK3R1 Sponge network -2.202 0.00081 -0.892 0 0.357
18 PART1 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-26a-5p;hsa-miR-30e-3p 10 PRKAA2 Sponge network 3.525 1.0E-5 0.91 0.01333 0.351
19 RP11-250B2.6 hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-188-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -0.98 2.0E-5 -0.892 0 0.342
20 AP000473.5 hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-338-5p 11 PIK3R1 Sponge network -1.157 0.00884 -0.892 0 0.341
21 RP11-963H4.3 hsa-miR-106b-5p;hsa-miR-15b-5p;hsa-miR-17-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-324-3p;hsa-miR-590-5p;hsa-miR-629-3p;hsa-miR-93-5p 10 PIK3R1 Sponge network -1.857 0.00116 -0.892 0 0.328
22 RP11-440G9.1 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-26a-5p 10 PRKAA2 Sponge network 4.78 0 0.91 0.01333 0.324
23 RP11-407B7.1 hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-188-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-324-3p;hsa-miR-338-5p;hsa-miR-582-5p;hsa-miR-629-3p;hsa-miR-93-5p 13 PIK3R1 Sponge network -0.818 0.00584 -0.892 0 0.324
24 RP1-140K8.5 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-26a-5p 10 PRKAA2 Sponge network 1.954 0 0.91 0.01333 0.323
25 LINC00864 hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-15b-5p;hsa-miR-185-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-629-3p 10 PIK3R1 Sponge network -3.954 0 -0.892 0 0.322
26

MAGI2-AS3

hsa-miR-106b-5p;hsa-miR-107;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-362-3p;hsa-miR-362-5p;hsa-miR-421;hsa-miR-616-5p;hsa-miR-93-5p 10 AKT3 Sponge network -1.801 0 -0.659 0.00047 0.322
27 RP11-166D19.1 hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-15b-5p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-188-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-222-3p;hsa-miR-324-3p;hsa-miR-589-3p;hsa-miR-590-5p;hsa-miR-629-3p 14 PIK3R1 Sponge network -0.244 0.28835 -0.892 0 0.32
28 LINC00511 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-26a-5p;hsa-miR-30e-3p;hsa-miR-30e-5p;hsa-miR-628-3p 12 PRKAA2 Sponge network 2.468 0 0.91 0.01333 0.309
29 DLGAP1-AS2 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-26a-5p;hsa-miR-30e-3p 11 PRKAA2 Sponge network 1.357 0 0.91 0.01333 0.306
30 LINC00885 hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-188-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-324-3p 10 PIK3R1 Sponge network -4.686 0 -0.892 0 0.3
31

MAGI2-AS3

hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-15b-5p;hsa-miR-17-5p;hsa-miR-188-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-589-3p;hsa-miR-629-3p;hsa-miR-93-5p 13 PIK3R1 Sponge network -1.801 0 -0.892 0 0.294
32 GAS5 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p;hsa-miR-576-5p 13 PRKAA2 Sponge network 1.966 0 0.91 0.01333 0.294
33 DLGAP1-AS1 hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-5p 10 PRKAA2 Sponge network 0.91 0 0.91 0.01333 0.293
34 AC005562.1 hsa-let-7b-3p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p;hsa-miR-30e-5p;hsa-miR-628-3p 13 PRKAA2 Sponge network 1.127 0 0.91 0.01333 0.29
35 AC016747.3 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-5p;hsa-miR-576-5p 13 PRKAA2 Sponge network 1.235 0 0.91 0.01333 0.29
36 RP4-717I23.3 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p;hsa-miR-628-3p 13 PRKAA2 Sponge network 1.867 0 0.91 0.01333 0.285
37 RP1-228H13.5 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p;hsa-miR-30e-5p;hsa-miR-576-5p 14 PRKAA2 Sponge network 1.554 0 0.91 0.01333 0.285
38

AC005550.3

hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-188-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-629-3p 10 PIK3R1 Sponge network -2.571 0.00132 -0.892 0 0.281
39 AP001469.9 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p;hsa-miR-30e-5p;hsa-miR-576-5p 13 PRKAA2 Sponge network 2.428 0 0.91 0.01333 0.279
40 AC074117.10 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p 12 PRKAA2 Sponge network 1.254 0 0.91 0.01333 0.275
41 RP11-121C2.2 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p;hsa-miR-30e-5p 12 PRKAA2 Sponge network 1.286 0 0.91 0.01333 0.273
42 RP11-7F17.3 hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-188-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-324-3p 11 PIK3R1 Sponge network -0.873 0.00204 -0.892 0 0.271
43 SMIM2-AS1 hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-589-3p;hsa-miR-629-3p 13 PIK3R1 Sponge network -0.66 0.00587 -0.892 0 0.27
44 RP11-133K1.6 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-576-5p 10 PRKAA2 Sponge network 1.056 0 0.91 0.01333 0.269
45 TMCC1-AS1 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p 11 PRKAA2 Sponge network 2.298 0 0.91 0.01333 0.258
46 NUTM2A-AS1 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-139-5p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p;hsa-miR-576-5p 10 PRKAA2 Sponge network 0.788 0 0.91 0.01333 0.256
47 WAC-AS1 hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p 10 PRKAA2 Sponge network 0.869 0 0.91 0.01333 0.255
48 HCG20 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-5p 10 PRKAA2 Sponge network 3.632 0 0.91 0.01333 0.253
49 KB-1460A1.5 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p 11 PRKAA2 Sponge network 1.949 0 0.91 0.01333 0.253
50 LINC00680 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p 11 PRKAA2 Sponge network 1.404 0 0.91 0.01333 0.252
51 AC073283.4 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-126-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p;hsa-miR-30e-5p 13 PRKAA2 Sponge network 1.514 0 0.91 0.01333 0.251

Quest ID: af000066de3dc5b4149e4835afc3efc9