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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-106a-5p AADAC -0.46 0.00972 -1.53 0 MirTarget -0.23 0.00808 NA
2 hsa-miR-106b-5p AADAC 0.65 0 -1.53 0 MirTarget -0.77 0 NA
3 hsa-miR-93-5p AADAC 1.4 0 -1.53 0 MirTarget -0.44 6.0E-5 NA
4 hsa-miR-106b-5p ABCA1 0.65 0 -1.1 0 MirTarget; miRNATAP -0.19 0.00194 NA
5 hsa-miR-93-5p ABCA1 1.4 0 -1.1 0 MirTarget; miRNATAP -0.2 5.0E-5 NA
6 hsa-miR-106a-5p ABHD2 -0.46 0.00972 -1.2 0 miRNATAP -0.11 0.00947 NA
7 hsa-miR-106b-5p ABHD2 0.65 0 -1.2 0 miRNATAP -0.46 0 NA
8 hsa-miR-93-5p ABHD2 1.4 0 -1.2 0 miRNATAP -0.47 0 NA
9 hsa-miR-106b-5p ABHD5 0.65 0 -0.6 0 MirTarget -0.19 1.0E-5 NA
10 hsa-miR-93-5p ABHD5 1.4 0 -0.6 0 MirTarget -0.21 0 NA
11 hsa-miR-20a-3p ABLIM1 -0.32 0.04679 0.05 0.66786 mirMAP -0.15 0 NA
12 hsa-miR-106b-5p ABTB2 0.65 0 -0.43 0.0031 miRNAWalker2 validate -0.25 5.0E-5 NA
13 hsa-miR-106a-5p ACOX1 -0.46 0.00972 -1.16 0 mirMAP -0.12 0.00203 NA
14 hsa-miR-106b-5p ACOX1 0.65 0 -1.16 0 mirMAP -0.51 0 NA
15 hsa-miR-93-5p ACOX1 1.4 0 -1.16 0 mirMAP -0.41 0 NA
16 hsa-miR-106a-5p ACSL6 -0.46 0.00972 0.39 0.26458 mirMAP -0.57 0 NA
17 hsa-miR-106b-5p ACSL6 0.65 0 0.39 0.26458 mirMAP -0.64 2.0E-5 NA
18 hsa-miR-106a-5p ACTR3C -0.46 0.00972 -0.99 0 mirMAP -0.15 0.00144 NA
19 hsa-miR-106b-5p ACTR3C 0.65 0 -0.99 0 mirMAP -0.5 0 NA
20 hsa-miR-93-5p ACTR3C 1.4 0 -0.99 0 mirMAP -0.34 0 NA
21 hsa-miR-106b-5p ADARB1 0.65 0 -0.13 0.22208 MirTarget -0.22 0 NA
22 hsa-miR-20a-3p ADARB1 -0.32 0.04679 -0.13 0.22208 mirMAP -0.15 0 NA
23 hsa-miR-93-5p ADARB1 1.4 0 -0.13 0.22208 miRNAWalker2 validate; MirTarget -0.21 0 NA
24 hsa-miR-106b-5p ADCY1 0.65 0 -2.7 0 mirMAP -0.54 0.00112 NA
25 hsa-miR-93-5p ADCY1 1.4 0 -2.7 0 mirMAP -0.65 0 NA
26 hsa-miR-106b-5p ADCY9 0.65 0 -0.11 0.30518 mirMAP -0.23 0 NA
27 hsa-miR-93-5p ADCY9 1.4 0 -0.11 0.30518 mirMAP -0.14 0.0003 NA
28 hsa-miR-106b-5p ADH5 0.65 0 -0.53 0 miRNAWalker2 validate -0.27 0 NA
29 hsa-miR-106b-5p ADRA2A 0.65 0 -0.76 0.02558 miRNATAP -0.6 3.0E-5 NA
30 hsa-miR-106a-5p AEN -0.46 0.00972 0.28 0.01239 MirTarget -0.13 1.0E-5 NA
31 hsa-miR-106b-5p AFF4 0.65 0 -0.64 0 miRNATAP -0.27 0 NA
32 hsa-miR-93-5p AFF4 1.4 0 -0.64 0 miRNATAP -0.27 0 NA
33 hsa-miR-106b-5p AGA 0.65 0 0.02 0.86356 MirTarget -0.17 0.00102 NA
34 hsa-miR-106a-5p AGFG2 -0.46 0.00972 -0.02 0.87061 miRNATAP -0.16 0 NA
35 hsa-miR-20a-3p AGFG2 -0.32 0.04679 -0.02 0.87061 mirMAP -0.12 0.00068 NA
36 hsa-miR-20a-3p AIFM1 -0.32 0.04679 -0.39 0.00049 miRNATAP -0.11 0.00067 NA
37 hsa-miR-106b-5p AKAP11 0.65 0 -0.7 0 miRNAWalker2 validate -0.25 0 NA
38 hsa-miR-93-5p AKAP11 1.4 0 -0.7 0 miRNAWalker2 validate -0.25 0 NA
39 hsa-miR-106b-5p AKAP13 0.65 0 -0.32 0.00142 MirTarget; mirMAP; miRNATAP -0.23 0 NA
40 hsa-miR-93-5p AKAP13 1.4 0 -0.32 0.00142 MirTarget; miRNATAP -0.26 0 NA
41 hsa-miR-20a-3p AKAP6 -0.32 0.04679 -0.97 0 MirTarget -0.3 0 NA
42 hsa-miR-93-5p AKIRIN1 1.4 0 -0.73 0 mirMAP -0.14 2.0E-5 NA
43 hsa-miR-106b-5p AKT3 0.65 0 -0.66 0.00047 miRNATAP -0.26 0.00148 NA
44 hsa-miR-93-5p AKT3 1.4 0 -0.66 0.00047 miRNATAP -0.28 1.0E-5 NA
45 hsa-miR-106a-5p AKTIP -0.46 0.00972 -0.37 0.00054 MirTarget; miRNATAP -0.12 3.0E-5 NA
46 hsa-miR-106b-5p AKTIP 0.65 0 -0.37 0.00054 MirTarget; miRNATAP -0.36 0 NA
47 hsa-miR-93-5p AKTIP 1.4 0 -0.37 0.00054 MirTarget; miRNATAP -0.29 0 NA
48 hsa-miR-93-5p ALDH1A3 1.4 0 -2.13 0 mirMAP -0.81 0 NA
49 hsa-miR-106b-5p ALDH3A2 0.65 0 -0.55 0.00022 mirMAP -0.45 0 NA
50 hsa-miR-20a-3p ALDH3A2 -0.32 0.04679 -0.55 0.00022 mirMAP -0.14 0.00285 NA
51 hsa-miR-20a-3p ANGPTL1 -0.32 0.04679 -2.91 0 MirTarget -0.36 0.00116 NA
52 hsa-miR-93-5p ANK2 1.4 0 -0.94 8.0E-5 MirTarget; miRNATAP -0.24 0.00324 NA
53 hsa-miR-106b-5p ANKFY1 0.65 0 -0.58 0 miRNAWalker2 validate; MirTarget -0.24 0 NA
54 hsa-miR-20a-3p ANKFY1 -0.32 0.04679 -0.58 0 MirTarget -0.1 0.00012 NA
55 hsa-miR-93-5p ANKFY1 1.4 0 -0.58 0 miRNAWalker2 validate -0.22 0 NA
56 hsa-miR-93-5p ANKH 1.4 0 -0.35 0.00159 MirTarget -0.1 0.00683 NA
57 hsa-miR-93-5p ANKRD12 1.4 0 -0.35 0.00044 MirTarget -0.12 0.00046 NA
58 hsa-miR-106a-5p ANKRD29 -0.46 0.00972 1.13 4.0E-5 MirTarget -0.48 0 NA
59 hsa-miR-106b-5p ANKRD29 0.65 0 1.13 4.0E-5 MirTarget -0.64 0 NA
60 hsa-miR-93-5p ANKRD29 1.4 0 1.13 4.0E-5 miRNAWalker2 validate; MirTarget -0.37 0.0001 NA
61 hsa-miR-20a-3p ANKRD50 -0.32 0.04679 -0.25 0.04433 MirTarget; miRNATAP -0.14 0.00021 NA
62 hsa-miR-93-5p ANKRD50 1.4 0 -0.25 0.04433 MirTarget; miRNATAP -0.16 0.00022 NA
63 hsa-miR-106b-5p ANO6 0.65 0 -0.29 0.00464 MirTarget -0.14 0.00107 NA
64 hsa-miR-93-5p ANO6 1.4 0 -0.29 0.00464 MirTarget; miRNATAP -0.11 0.0016 NA
65 hsa-miR-93-5p AP1AR 1.4 0 -0.61 0 miRNAWalker2 validate -0.26 0 NA
66 hsa-miR-106b-5p AP1G1 0.65 0 -0.48 0 miRNAWalker2 validate -0.28 0 NA
67 hsa-miR-93-5p AP1G1 1.4 0 -0.48 0 miRNAWalker2 validate -0.25 0 NA
68 hsa-miR-106b-5p AP3S2 0.65 0 -0.33 4.0E-5 mirMAP -0.2 0 NA
69 hsa-miR-93-5p AP3S2 1.4 0 -0.33 4.0E-5 mirMAP -0.17 0 NA
70 hsa-miR-106a-5p APBB2 -0.46 0.00972 -0.24 0.03085 MirTarget; miRNATAP -0.14 0 NA
71 hsa-miR-106b-5p APBB2 0.65 0 -0.24 0.03085 MirTarget; miRNATAP -0.21 1.0E-5 NA
72 hsa-miR-93-5p APBB2 1.4 0 -0.24 0.03085 miRNAWalker2 validate; MirTarget; miRNATAP -0.17 0 NA
73 hsa-miR-106b-5p APC 0.65 0 -0.18 0.06792 miRNAWalker2 validate; miRTarBase -0.15 0.00024 23087084 miR 106b downregulates adenomatous polyposis coli and promotes cell proliferation in human hepatocellular carcinoma; Moreover we demonstrated that miR-106b downregulates APC expression by directly targeting the 3'-untranslated region of APC messenger RNA; Taken together our results suggest that miR-106b plays an important role in promoting the proliferation of human hepatoma cells and presents a novel mechanism of micro RNA-mediated direct suppression of APC expression in cancer cells
74 hsa-miR-20a-3p APC2 -0.32 0.04679 1.72 0 mirMAP -0.25 7.0E-5 NA
75 hsa-miR-106a-5p AR -0.46 0.00972 -2.66 0 mirMAP -0.48 2.0E-5 NA
76 hsa-miR-106b-5p AR 0.65 0 -2.66 0 mirMAP -1.42 0 NA
77 hsa-miR-93-5p AR 1.4 0 -2.66 0 mirMAP -1.11 0 NA
78 hsa-miR-93-5p ARAP2 1.4 0 -1.13 0 MirTarget -0.33 0 NA
79 hsa-miR-106b-5p ARHGAP23 0.65 0 -0.14 0.32985 mirMAP -0.31 0 NA
80 hsa-miR-93-5p ARHGAP23 1.4 0 -0.14 0.32985 mirMAP -0.27 0 NA
81 hsa-miR-106b-5p ARHGAP24 0.65 0 -0.99 0 MirTarget -0.32 3.0E-5 NA
82 hsa-miR-93-5p ARHGAP24 1.4 0 -0.99 0 MirTarget -0.4 0 NA
83 hsa-miR-106b-5p ARID4A 0.65 0 -0.9 0 MirTarget; miRNATAP -0.14 0.00925 NA
84 hsa-miR-93-5p ARID4A 1.4 0 -0.9 0 MirTarget; miRNATAP -0.21 0 NA
85 hsa-miR-93-5p ARL10 1.4 0 -0.42 0.01556 mirMAP -0.2 0.00063 NA
86 hsa-miR-106b-5p ARSB 0.65 0 0 0.99867 mirMAP -0.15 0.00457 NA
87 hsa-miR-106a-5p ARSD -0.46 0.00972 -1.16 0 mirMAP -0.2 0 NA
88 hsa-miR-106b-5p ARSD 0.65 0 -1.16 0 mirMAP -0.48 0 NA
89 hsa-miR-93-5p ARSJ 1.4 0 -1.41 0 miRNAWalker2 validate -0.44 0 NA
90 hsa-miR-20a-3p ASAP2 -0.32 0.04679 0.69 2.0E-5 MirTarget -0.32 0 NA
91 hsa-miR-106b-5p ASPA 0.65 0 -2.88 0 mirMAP -0.58 0 NA
92 hsa-miR-93-5p ASPA 1.4 0 -2.88 0 mirMAP -0.79 0 NA
93 hsa-miR-106b-5p ATE1 0.65 0 -0.6 0.0009 MirTarget -0.21 0.00742 NA
94 hsa-miR-93-5p ATE1 1.4 0 -0.6 0.0009 MirTarget -0.25 5.0E-5 NA
95 hsa-miR-106b-5p ATF6 0.65 0 -0.02 0.87055 mirMAP -0.25 0 NA
96 hsa-miR-93-5p ATF6 1.4 0 -0.02 0.87055 mirMAP -0.16 1.0E-5 NA
97 hsa-miR-106b-5p ATG2A 0.65 0 -0.78 0 miRNATAP -0.15 0.00025 NA
98 hsa-miR-93-5p ATG2A 1.4 0 -0.78 0 miRNATAP -0.2 0 NA
99 hsa-miR-106a-5p ATP1A2 -0.46 0.00972 0.51 0.11121 MirTarget -0.24 0.00583 NA
100 hsa-miR-106b-5p ATP1A2 0.65 0 0.51 0.11121 MirTarget; miRNATAP -0.67 0 NA
101 hsa-miR-93-5p ATP1A2 1.4 0 0.51 0.11121 MirTarget -0.29 0.00874 NA
102 hsa-miR-93-5p ATP5B 1.4 0 -0.12 0.15018 miRNAWalker2 validate -0.12 3.0E-5 NA
103 hsa-miR-106a-5p ATXN1L -0.46 0.00972 0.09 0.38956 miRNATAP -0.11 0.00013 NA
104 hsa-miR-93-5p B2M 1.4 0 -0.47 0.00029 miRNAWalker2 validate -0.39 0 NA
105 hsa-miR-93-5p BACH1 1.4 0 -0.63 0 mirMAP -0.14 0.00086 NA
106 hsa-miR-20a-3p BCL2 -0.32 0.04679 -0.35 0.02497 mirMAP -0.24 0 NA
107 hsa-miR-93-5p BHLHE41 1.4 0 -0.4 0.15906 miRNATAP -0.3 0.00244 NA
108 hsa-miR-106b-5p BMPR2 0.65 0 -0.74 0 MirTarget; miRNATAP -0.22 0 NA
109 hsa-miR-93-5p BMPR2 1.4 0 -0.74 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.27 0 NA
110 hsa-miR-106b-5p BNC2 0.65 0 -0.39 0.08973 miRNATAP -0.35 0.00032 NA
111 hsa-miR-93-5p BNC2 1.4 0 -0.39 0.08973 miRNATAP -0.4 0 NA
112 hsa-miR-106b-5p BNIP2 0.65 0 -0.74 0 MirTarget; miRNATAP -0.17 0 NA
113 hsa-miR-93-5p BNIP2 1.4 0 -0.74 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.21 0 NA
114 hsa-miR-106b-5p BNIP3L 0.65 0 -0.67 0 MirTarget -0.15 0.0011 NA
115 hsa-miR-93-5p BNIP3L 1.4 0 -0.67 0 MirTarget -0.12 0.00081 NA
116 hsa-miR-93-5p BRMS1L 1.4 0 -0.38 0 MirTarget; miRNATAP -0.12 2.0E-5 NA
117 hsa-miR-106b-5p BTN3A3 0.65 0 -0.38 0.00816 miRNAWalker2 validate -0.42 0 NA
118 hsa-miR-106b-5p C14orf28 0.65 0 -0.34 0.00119 miRNATAP -0.21 0 NA
119 hsa-miR-93-5p C14orf28 1.4 0 -0.34 0.00119 miRNATAP -0.12 0.00058 NA
120 hsa-miR-106a-5p C16orf52 -0.46 0.00972 -0.5 0 miRNATAP -0.12 2.0E-5 NA
121 hsa-miR-106b-5p C16orf52 0.65 0 -0.5 0 miRNATAP -0.28 0 NA
122 hsa-miR-93-5p C16orf52 1.4 0 -0.5 0 miRNATAP -0.2 0 NA
123 hsa-miR-106b-5p C16orf70 0.65 0 -0.77 0 miRNATAP -0.36 0 NA
124 hsa-miR-93-5p C16orf87 1.4 0 -0.85 0 mirMAP -0.26 0 NA
125 hsa-miR-20a-3p C17orf51 -0.32 0.04679 -0.67 0.00164 mirMAP -0.22 0.00089 NA
126 hsa-miR-20a-3p C1orf21 -0.32 0.04679 -0.75 0.00045 mirMAP -0.26 9.0E-5 NA
127 hsa-miR-106b-5p C3orf70 0.65 0 0.49 0.00136 miRNATAP -0.19 0.00352 NA
128 hsa-miR-106b-5p C4orf3 0.65 0 -0.76 0 mirMAP -0.31 0 NA
129 hsa-miR-20a-3p CACNB4 -0.32 0.04679 1.93 0 miRNATAP -0.38 3.0E-5 NA
130 hsa-miR-20a-3p CADPS2 -0.32 0.04679 0.02 0.88551 MirTarget -0.15 0.00104 NA
131 hsa-miR-93-5p CALCOCO2 1.4 0 -0.31 1.0E-5 miRNAWalker2 validate -0.15 0 NA
132 hsa-miR-106b-5p CALD1 0.65 0 -0.53 0 miRNATAP -0.31 0 NA
133 hsa-miR-93-5p CALD1 1.4 0 -0.53 0 miRNATAP -0.23 0 NA
134 hsa-miR-106a-5p CALML4 -0.46 0.00972 0.01 0.91319 mirMAP -0.11 0.0004 NA
135 hsa-miR-20a-3p CAMK1D -0.32 0.04679 -0.4 0.12354 mirMAP -0.5 0 NA
136 hsa-miR-106b-5p CAMTA2 0.65 0 -0.35 8.0E-5 MirTarget -0.15 8.0E-5 NA
137 hsa-miR-93-5p CAMTA2 1.4 0 -0.35 8.0E-5 MirTarget -0.14 1.0E-5 NA
138 hsa-miR-20a-3p CAPN2 -0.32 0.04679 0.66 0 MirTarget -0.13 0.00067 NA
139 hsa-miR-106b-5p CASC4 0.65 0 -0.46 0 MirTarget -0.23 0 NA
140 hsa-miR-93-5p CASC4 1.4 0 -0.46 0 MirTarget -0.25 0 NA
141 hsa-miR-106a-5p CASK -0.46 0.00972 0.43 0.00011 mirMAP -0.1 0.00062 NA
142 hsa-miR-20a-3p CASK -0.32 0.04679 0.43 0.00011 mirMAP -0.22 0 NA
143 hsa-miR-93-5p CAV2 1.4 0 -0.67 0.00155 miRNAWalker2 validate -0.26 0.00029 NA
144 hsa-miR-106b-5p CBLN4 0.65 0 -1.67 0.00015 miRNATAP -1.04 0 NA
145 hsa-miR-106a-5p CBX7 -0.46 0.00972 -0.08 0.52937 mirMAP -0.2 0 NA
146 hsa-miR-106b-5p CBX7 0.65 0 -0.08 0.52937 mirMAP -0.33 0 NA
147 hsa-miR-93-5p CBX7 1.4 0 -0.08 0.52937 mirMAP -0.19 0 NA
148 hsa-miR-106a-5p CC2D1A -0.46 0.00972 0.26 0.00869 MirTarget; miRNATAP -0.16 0 NA
149 hsa-miR-106b-5p CCBE1 0.65 0 -5.46 0 mirMAP -1.06 0 NA
150 hsa-miR-93-5p CCBE1 1.4 0 -5.46 0 mirMAP -1.25 0 NA
NumGOOverlapSizeP ValueAdj. P Value
1 INTRACELLULAR SIGNAL TRANSDUCTION 111 1572 7.002e-12 3.258e-08
2 RESPONSE TO ENDOGENOUS STIMULUS 103 1450 3.22e-11 7.492e-08
3 REGULATION OF CELL DIFFERENTIATION 104 1492 7.632e-11 1.184e-07
4 CARDIOVASCULAR SYSTEM DEVELOPMENT 66 788 2.35e-10 2.187e-07
5 CIRCULATORY SYSTEM DEVELOPMENT 66 788 2.35e-10 2.187e-07
6 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 110 1672 6.08e-10 4.042e-07
7 REGULATION OF PROTEIN MODIFICATION PROCESS 112 1710 5.347e-10 4.042e-07
8 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 100 1492 1.569e-09 8.603e-07
9 REGULATION OF PHOSPHORUS METABOLIC PROCESS 106 1618 1.664e-09 8.603e-07
10 POSITIVE REGULATION OF MOLECULAR FUNCTION 113 1791 3.816e-09 1.646e-06
11 TISSUE DEVELOPMENT 100 1518 3.892e-09 1.646e-06
12 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 74 1008 6.471e-09 2.509e-06
13 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 105 1656 1.158e-08 3.931e-06
14 CELL DEVELOPMENT 94 1426 1.183e-08 3.931e-06
15 POSITIVE REGULATION OF CATABOLIC PROCESS 39 395 1.717e-08 5.326e-06
16 TELENCEPHALON DEVELOPMENT 28 228 1.885e-08 5.481e-06
17 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 79 1135 2.01e-08 5.501e-06
18 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 110 1784 2.215e-08 5.725e-06
19 POSITIVE REGULATION OF RESPONSE TO STIMULUS 116 1929 3.398e-08 8.321e-06
20 NEGATIVE REGULATION OF CELL COMMUNICATION 81 1192 3.731e-08 8.681e-06
21 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 112 1848 4.06e-08 8.988e-06
22 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 89 1360 4.25e-08 8.988e-06
23 HEART DEVELOPMENT 42 466 6.615e-08 1.338e-05
24 REGULATION OF KINASE ACTIVITY 59 776 7.325e-08 1.42e-05
25 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 54 689 1.009e-07 1.878e-05
26 REGULATION OF TRANSFERASE ACTIVITY 67 946 1.37e-07 2.451e-05
27 HOMEOSTATIC PROCESS 86 1337 1.566e-07 2.682e-05
28 MUSCLE CELL DIFFERENTIATION 27 237 1.614e-07 2.682e-05
29 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 14 70 1.818e-07 2.917e-05
30 POSITIVE REGULATION OF GENE EXPRESSION 104 1733 2.178e-07 3.269e-05
31 VASCULATURE DEVELOPMENT 41 469 2.165e-07 3.269e-05
32 POSITIVE REGULATION OF CATALYTIC ACTIVITY 94 1518 2.249e-07 3.27e-05
33 REGULATION OF CATABOLIC PROCESS 55 731 2.892e-07 3.958e-05
34 NEGATIVE REGULATION OF PHOSPHORYLATION 38 422 2.873e-07 3.958e-05
35 REGULATION OF CELLULAR COMPONENT MOVEMENT 57 771 3.111e-07 4.136e-05
36 NEUROGENESIS 88 1402 3.219e-07 4.16e-05
37 FOREBRAIN DEVELOPMENT 34 357 3.338e-07 4.198e-05
38 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 26 232 3.768e-07 4.614e-05
39 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 114 1977 4.054e-07 4.836e-05
40 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 106 1805 4.685e-07 5.45e-05
41 EPITHELIUM DEVELOPMENT 65 945 5.997e-07 6.806e-05
42 RESPONSE TO OXYGEN CONTAINING COMPOUND 86 1381 6.19e-07 6.857e-05
43 POSITIVE REGULATION OF CELL COMMUNICATION 93 1532 6.34e-07 6.86e-05
44 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 21 166 6.822e-07 7.214e-05
45 PALLIUM DEVELOPMENT 20 153 7.401e-07 7.653e-05
46 CHEMICAL HOMEOSTASIS 61 874 8.376e-07 8.297e-05
47 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 69 1036 8.559e-07 8.297e-05
48 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 69 1036 8.559e-07 8.297e-05
49 POSITIVE REGULATION OF NEURON DIFFERENTIATION 30 306 8.928e-07 8.478e-05
50 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 67 1004 1.163e-06 0.0001083
51 MUSCLE STRUCTURE DEVELOPMENT 37 432 1.383e-06 0.0001238
52 TRANSITION METAL ION HOMEOSTASIS 16 106 1.378e-06 0.0001238
53 PROTEIN CATABOLIC PROCESS 45 579 1.505e-06 0.0001297
54 BLOOD VESSEL MORPHOGENESIS 33 364 1.496e-06 0.0001297
55 RESPONSE TO HORMONE 61 893 1.696e-06 0.0001435
56 NEURON DIFFERENTIATION 60 874 1.766e-06 0.0001467
57 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 37 437 1.816e-06 0.0001483
58 REGULATION OF CELL DEVELOPMENT 58 836 1.902e-06 0.0001526
59 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 56 799 2.111e-06 0.0001615
60 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 67 1021 2.077e-06 0.0001615
61 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 53 740 2.118e-06 0.0001615
62 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 41 513 2.206e-06 0.0001629
63 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 29 303 2.2e-06 0.0001629
64 REGULATION OF NEURON DIFFERENTIATION 43 554 2.665e-06 0.0001938
65 REGULATION OF CELL PROJECTION ORGANIZATION 43 558 3.204e-06 0.0002293
66 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 24 229 3.46e-06 0.0002303
67 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 42 541 3.464e-06 0.0002303
68 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 42 541 3.464e-06 0.0002303
69 CENTRAL NERVOUS SYSTEM DEVELOPMENT 59 872 3.403e-06 0.0002303
70 REGULATION OF GTPASE ACTIVITY 49 673 3.29e-06 0.0002303
71 CELLULAR HOMEOSTASIS 49 676 3.72e-06 0.0002438
72 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 63 957 3.838e-06 0.000248
73 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 38 470 3.957e-06 0.0002522
74 RESPONSE TO NITROGEN COMPOUND 58 859 4.399e-06 0.0002693
75 POSITIVE REGULATION OF CELL DEVELOPMENT 38 472 4.37e-06 0.0002693
76 MESONEPHROS DEVELOPMENT 14 90 4.345e-06 0.0002693
77 CELLULAR CATABOLIC PROCESS 80 1322 4.697e-06 0.0002838
78 ORGAN MORPHOGENESIS 57 841 4.76e-06 0.0002839
79 POSITIVE REGULATION OF LOCOMOTION 35 420 4.9e-06 0.0002886
80 NEGATIVE REGULATION OF KINASE ACTIVITY 25 250 5.055e-06 0.0002938
81 STRIATED MUSCLE CELL DIFFERENTIATION 20 173 5.114e-06 0.0002938
82 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 31 352 5.613e-06 0.0003185
83 CELLULAR RESPONSE TO HORMONE STIMULUS 42 552 5.714e-06 0.0003203
84 HEAD DEVELOPMENT 50 709 6.34e-06 0.0003502
85 IRON ION HOMEOSTASIS 12 69 6.398e-06 0.0003502
86 REGULATION OF NEURON PROJECTION DEVELOPMENT 34 408 6.679e-06 0.0003613
87 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 71 1142 6.763e-06 0.0003617
88 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 58 876 7.944e-06 0.0004153
89 REGULATION OF OSSIFICATION 20 178 7.887e-06 0.0004153
90 REGULATION OF HYDROLASE ACTIVITY 79 1327 9.801e-06 0.0005067
91 INTRINSIC APOPTOTIC SIGNALING PATHWAY 18 152 1.074e-05 0.0005493
92 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 26 278 1.103e-05 0.000558
93 SKELETAL SYSTEM DEVELOPMENT 36 455 1.141e-05 0.0005707
94 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 35 437 1.161e-05 0.0005748
95 KIDNEY EPITHELIUM DEVELOPMENT 16 125 1.227e-05 0.000601
96 TUBE DEVELOPMENT 41 552 1.31e-05 0.0006219
97 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 20 184 1.296e-05 0.0006219
98 REGULATION OF CELLULAR PROTEIN LOCALIZATION 41 552 1.31e-05 0.0006219
99 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 51 750 1.391e-05 0.0006539
100 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 38 498 1.489e-05 0.0006908
101 RESPONSE TO OXIDATIVE STRESS 30 352 1.499e-05 0.0006908
102 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 70 1152 1.681e-05 0.0007669
103 REGULATION OF MAPK CASCADE 46 660 2.002e-05 0.0008882
104 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 53 801 2.004e-05 0.0008882
105 REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 6 17 1.984e-05 0.0008882
106 MACROMOLECULE CATABOLIC PROCESS 59 926 2.073e-05 0.00091
107 PROTEIN LOCALIZATION 99 1805 2.144e-05 0.0009322
108 NEGATIVE REGULATION OF CELL PROLIFERATION 45 643 2.227e-05 0.0009594
109 NEGATIVE REGULATION OF CELL ADHESION 22 223 2.273e-05 0.0009684
110 PHOSPHORYLATION 73 1228 2.289e-05 0.0009684
111 NEURON DEVELOPMENT 47 687 2.602e-05 0.001088
112 MUSCLE TISSUE DEVELOPMENT 25 275 2.619e-05 0.001088
113 CEREBRAL CORTEX DEVELOPMENT 14 105 2.669e-05 0.001099
114 NEGATIVE REGULATION OF CELL DIFFERENTIATION 43 609 2.746e-05 0.001121
115 ENTRAINMENT OF CIRCADIAN CLOCK 7 26 2.927e-05 0.001184
116 CELL DEATH 62 1001 2.973e-05 0.001193
117 REGULATION OF DENDRITE DEVELOPMENT 15 120 3.03e-05 0.001205
118 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 80 1395 3.223e-05 0.001271
119 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 26 296 3.287e-05 0.001285
120 ION HOMEOSTASIS 41 576 3.505e-05 0.001359
121 PROTEIN PHOSPHORYLATION 59 944 3.605e-05 0.001386
122 REGULATION OF CYTOPLASMIC TRANSPORT 36 481 3.735e-05 0.001424
123 CENTRAL NERVOUS SYSTEM NEURON AXONOGENESIS 7 27 3.829e-05 0.001448
124 POSITIVE REGULATION OF HYDROLASE ACTIVITY 57 905 3.959e-05 0.001486
125 REGULATION OF BINDING 25 283 4.218e-05 0.00157
126 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 74 1275 4.415e-05 0.00163
127 CATABOLIC PROCESS 96 1773 4.756e-05 0.001743
128 EPITHELIAL CELL DEVELOPMENT 19 186 5.029e-05 0.001828
129 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 15 126 5.39e-05 0.001944
130 ENDOPLASMIC RETICULUM CALCIUM ION HOMEOSTASIS 6 20 5.658e-05 0.00201
131 REGULATION OF TRANSPORT 97 1804 5.64e-05 0.00201
132 REGULATION OF CELL SIZE 18 172 5.737e-05 0.002015
133 RESPONSE TO ABIOTIC STIMULUS 62 1024 5.759e-05 0.002015
134 REGULATION OF CELL ADHESION 43 629 5.818e-05 0.00202
135 TISSUE MORPHOGENESIS 38 533 6.509e-05 0.002227
136 MUSCLE CELL DEVELOPMENT 15 128 6.474e-05 0.002227
137 CELLULAR RESPONSE TO OXYGEN LEVELS 16 143 6.572e-05 0.002232
138 EPITHELIAL CELL DIFFERENTIATION 36 495 6.744e-05 0.002274
139 CELL PROJECTION ORGANIZATION 56 902 6.823e-05 0.002284
140 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 84 1517 6.935e-05 0.002305
141 REGULATION OF DENDRITE MORPHOGENESIS 11 74 7.041e-05 0.002307
142 REGULATION OF JNK CASCADE 17 159 6.992e-05 0.002307
143 ANGIOGENESIS 25 293 7.424e-05 0.002416
144 REGULATION OF CELLULAR LOCALIZATION 73 1277 8.048e-05 0.002547
145 REGULATION OF PROTEIN LOCALIZATION 58 950 8.004e-05 0.002547
146 POSITIVE REGULATION OF CELL DIFFERENTIATION 52 823 7.982e-05 0.002547
147 POSITIVE REGULATION OF AUTOPHAGY 11 75 7.984e-05 0.002547
148 DEVELOPMENTAL MATURATION 19 193 8.299e-05 0.002609
149 ORGANIC HYDROXY COMPOUND METABOLIC PROCESS 35 482 8.745e-05 0.002731
150 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 28 351 9.149e-05 0.002838
151 RHYTHMIC PROCESS 25 298 9.732e-05 0.002999
152 REGULATION OF CELL MATRIX ADHESION 12 90 9.911e-05 0.003034
153 CELLULAR RESPONSE TO NITROGEN COMPOUND 36 505 0.0001009 0.003069
154 UROGENITAL SYSTEM DEVELOPMENT 25 299 0.0001026 0.003101
155 NEURON PROJECTION DEVELOPMENT 38 545 0.0001036 0.003104
156 POSITIVE REGULATION OF CELL DEATH 41 605 0.0001041 0.003104
157 REGULATION OF RESPONSE TO STRESS 81 1468 0.0001059 0.003139
158 NEGATIVE REGULATION OF GENE EXPRESSION 82 1493 0.0001116 0.003285
159 REGULATION OF CELLULAR COMPONENT SIZE 27 337 0.000113 0.003285
160 LOCOMOTION 65 1114 0.0001124 0.003285
161 REGULATION OF PROTEIN CATABOLIC PROCESS 30 393 0.000115 0.003323
162 REGULATION OF CELL PROLIFERATION 82 1496 0.0001192 0.003424
163 NEGATIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 7 32 0.0001239 0.003514
164 POSITIVE REGULATION OF DENDRITE MORPHOGENESIS 7 32 0.0001239 0.003514
165 REGULATION OF ANATOMICAL STRUCTURE SIZE 34 472 0.0001281 0.00359
166 RESPONSE TO EXTERNAL STIMULUS 96 1821 0.0001279 0.00359
167 PROTEOLYSIS 69 1208 0.0001301 0.003625
168 REGULATION OF CELL MORPHOGENESIS 38 552 0.0001345 0.003726
169 CELLULAR MACROMOLECULE LOCALIZATION 70 1234 0.0001426 0.003926
170 RESPONSE TO GROWTH FACTOR 34 475 0.0001445 0.003954
171 SPHINGOLIPID METABOLIC PROCESS 15 138 0.0001527 0.004118
172 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 41 616 0.0001531 0.004118
173 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 41 616 0.0001531 0.004118
174 REGULATION OF DEVELOPMENTAL GROWTH 24 289 0.0001555 0.004135
175 APOPTOTIC SIGNALING PATHWAY 24 289 0.0001555 0.004135
176 CARDIAC MUSCLE TISSUE DEVELOPMENT 15 140 0.0001793 0.00474
177 CELLULAR RESPONSE TO PEPTIDE 23 274 0.0001809 0.004755
178 PLATELET DERIVED GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 7 34 0.0001859 0.004778
179 RESPONSE TO FLUID SHEAR STRESS 7 34 0.0001859 0.004778
180 ER NUCLEUS SIGNALING PATHWAY 7 34 0.0001859 0.004778
181 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 16 156 0.0001843 0.004778
182 RESPONSE TO OXYGEN LEVELS 25 311 0.00019 0.004858
183 REGULATION OF CELL SUBSTRATE ADHESION 17 173 0.0001974 0.004991
184 CELLULAR RESPONSE TO STRESS 84 1565 0.0001963 0.004991
185 POST GOLGI VESICLE MEDIATED TRANSPORT 11 83 0.0002023 0.005073
186 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 28 368 0.0002028 0.005073
187 CELLULAR COMPONENT MORPHOGENESIS 54 900 0.0002177 0.005416
188 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE 10 71 0.0002357 0.005832
189 PROTEIN UBIQUITINATION 41 629 0.0002373 0.005842
190 RESPONSE TO MECHANICAL STIMULUS 19 210 0.0002509 0.006143
191 POSITIVE REGULATION OF MAPK CASCADE 33 470 0.0002559 0.006171
192 CELL JUNCTION ASSEMBLY 14 129 0.0002549 0.006171
193 CELLULAR CHEMICAL HOMEOSTASIS 38 570 0.000256 0.006171
194 POSITIVE REGULATION OF PROTEIN CATABOLIC PROCESS 22 263 0.0002603 0.006242
195 REGULATION OF GROWTH 41 633 0.0002705 0.006428
196 POSITIVE REGULATION OF AXON EXTENSION 7 36 0.0002708 0.006428
197 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 26 337 0.0002725 0.006435
198 REGULATION OF LIPID METABOLIC PROCESS 23 282 0.0002747 0.006456
199 NEGATIVE REGULATION OF CELL CYCLE 31 433 0.0002788 0.006518
200 ESTABLISHMENT OF LOCALIZATION IN CELL 88 1676 0.0002857 0.006581
201 CELLULAR RESPONSE TO INSULIN STIMULUS 15 146 0.0002846 0.006581
202 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 16 162 0.0002842 0.006581
203 PROTEIN STABILIZATION 14 131 0.0002993 0.006859
204 COLUMNAR CUBOIDAL EPITHELIAL CELL DEVELOPMENT 8 48 0.0003052 0.006895
205 POSITIVE REGULATION OF RESPONSE TO EXTRACELLULAR STIMULUS 8 48 0.0003052 0.006895
206 POSITIVE REGULATION OF RESPONSE TO NUTRIENT LEVELS 8 48 0.0003052 0.006895
207 REGULATION OF CELL DEATH 79 1472 0.0003081 0.006925
208 GOLGI TO VACUOLE TRANSPORT 6 27 0.0003477 0.007778
209 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 14 133 0.0003501 0.007794
210 REGULATION OF INTRACELLULAR TRANSPORT 40 621 0.0003578 0.007928
211 REGULATION OF CIRCADIAN RHYTHM 12 103 0.0003603 0.007945
212 NEURON PROJECTION MORPHOGENESIS 29 402 0.0003829 0.008404
213 POSITIVE REGULATION OF KINASE ACTIVITY 33 482 0.0004015 0.00873
214 REGULATION OF VESICLE MEDIATED TRANSPORT 32 462 0.0004001 0.00873
215 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 14 135 0.0004081 0.008812
216 CELLULAR RESPONSE TO OXIDATIVE STRESS 17 184 0.0004091 0.008812
217 RESPONSE TO PEPTIDE 29 404 0.0004152 0.008902
218 VACUOLE ORGANIZATION 16 168 0.000428 0.009106
219 MUSCLE HYPERTROPHY 6 28 0.000429 0.009106
220 POSITIVE REGULATION OF JUN KINASE ACTIVITY 9 63 0.0004306 0.009106
221 VESICLE CYTOSKELETAL TRAFFICKING 7 39 0.0004539 0.009556
222 POSITIVE REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 4 11 0.0004658 0.009722
223 LYTIC VACUOLE ORGANIZATION 8 51 0.000468 0.009722
224 LYSOSOME ORGANIZATION 8 51 0.000468 0.009722
225 CIRCADIAN RHYTHM 14 137 0.0004741 0.009805
226 REGULATION OF PROTEIN STABILITY 19 221 0.0004768 0.009816
227 REGULATION OF HOMEOSTATIC PROCESS 31 447 0.0004798 0.009834
228 POSITIVE REGULATION OF DENDRITE DEVELOPMENT 9 64 0.0004851 0.0099
NumGOOverlapSizeP ValueAdj. P Value
1 ENZYME BINDING 121 1737 1.633e-12 1.517e-09
2 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 31 328 1.293e-06 0.0006006
3 MACROMOLECULAR COMPLEX BINDING 85 1399 1.964e-06 0.0006081
4 CYTOSKELETAL PROTEIN BINDING 56 819 4.45e-06 0.001034
5 UBIQUITIN LIKE PROTEIN TRANSFERASE ACTIVITY 33 420 3.017e-05 0.004004
6 PROTEIN HOMODIMERIZATION ACTIVITY 49 722 2.159e-05 0.004004
7 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 44 629 2.775e-05 0.004004
8 UBIQUITIN LIKE PROTEIN LIGASE BINDING 24 264 3.775e-05 0.004384
9 IDENTICAL PROTEIN BINDING 71 1209 4.393e-05 0.004535
10 PROTEIN DIMERIZATION ACTIVITY 68 1149 5.068e-05 0.004708
11 CALCIUM ION BINDING 46 697 7.517e-05 0.006349
12 PROTEIN KINASE ACTIVITY 43 640 8.618e-05 0.006672
13 RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 13 104 0.0001012 0.007231
14 RECEPTOR BINDING 81 1476 0.0001265 0.008395
15 KINASE ACTIVITY 52 842 0.0001412 0.008747
16 PROTEIN COMPLEX BINDING 56 935 0.0001745 0.009533
17 MOLECULAR FUNCTION REGULATOR 75 1353 0.0001679 0.009533
NumGOOverlapSizeP ValueAdj. P Value
1 MEMBRANE REGION 80 1134 8.963e-09 5.235e-06
2 MEMBRANE MICRODOMAIN 30 288 2.443e-07 7.134e-05
3 NEURON PART 81 1265 4.484e-07 8.729e-05
4 CELL LEADING EDGE 33 350 6.236e-07 9.104e-05
5 ACTIN CYTOSKELETON 38 444 1.015e-06 0.0001185
6 PERINUCLEAR REGION OF CYTOPLASM 47 642 4.518e-06 0.0004397
7 NEURON PROJECTION 61 942 9.152e-06 0.0007636
8 VACUOLE 72 1180 1.1e-05 0.0008033
9 ENDOPLASMIC RETICULUM 92 1631 1.495e-05 0.0009698
10 LAMELLIPODIUM 19 172 1.686e-05 0.0009844
11 PLASMA MEMBRANE REGION 59 929 2.277e-05 0.001108
12 GOLGI APPARATUS 83 1445 2.14e-05 0.001108
13 ENDOSOME 52 793 3.051e-05 0.001371
14 CYTOSKELETON 105 1967 3.6e-05 0.001502
15 CELL PROJECTION 96 1786 6.264e-05 0.002439
16 SYNAPSE 48 754 0.0001254 0.004487
17 CELL PROJECTION PART 57 946 0.0001306 0.004487
18 UBIQUITIN LIGASE COMPLEX 22 262 0.0002467 0.007105
19 CELL JUNCTION 65 1151 0.0002798 0.007105
20 CORTICAL ACTIN CYTOSKELETON 9 58 0.0002277 0.007105
21 MICROTUBULE PLUS END 5 17 0.0002691 0.007105
22 CATALYTIC COMPLEX 60 1038 0.0002644 0.007105
23 PLASMA MEMBRANE RAFT 11 86 0.0002779 0.007105
24 TRANSFERASE COMPLEX 44 703 0.0003428 0.008341

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04010_MAPK_signaling_pathway 25 268 1.694e-05 0.001724
2 hsa04210_Apoptosis 13 89 1.915e-05 0.001724
3 hsa04710_Circadian_rhythm_._mammal 6 23 0.0001342 0.008054
4 hsa04151_PI3K_AKT_signaling_pathway 26 351 0.0005075 0.02284
5 hsa04115_p53_signaling_pathway 9 69 0.0008498 0.03059
6 hsa04510_Focal_adhesion 17 200 0.001052 0.03155
7 hsa04360_Axon_guidance 12 130 0.002799 0.07198
8 hsa04380_Osteoclast_differentiation 11 128 0.007041 0.1493
9 hsa04144_Endocytosis 15 203 0.007464 0.1493
10 hsa04141_Protein_processing_in_endoplasmic_reticulum 13 168 0.008506 0.1531
11 hsa04390_Hippo_signaling_pathway 12 154 0.01064 0.1603
12 hsa04912_GnRH_signaling_pathway 9 101 0.01127 0.1603
13 hsa04920_Adipocytokine_signaling_pathway 7 68 0.01158 0.1603
14 hsa04014_Ras_signaling_pathway 16 236 0.01277 0.1642
15 hsa04914_Progesterone.mediated_oocyte_maturation 8 87 0.01377 0.1652
16 hsa00604_Glycosphingolipid_biosynthesis_._ganglio_series 3 15 0.0157 0.1766
17 hsa00071_Fatty_acid_metabolism 5 43 0.01926 0.1997
18 hsa00340_Histidine_metabolism 4 29 0.01997 0.1997
19 hsa04114_Oocyte_meiosis 9 114 0.02321 0.2199
20 hsa04270_Vascular_smooth_muscle_contraction 9 116 0.02564 0.2307
21 hsa04910_Insulin_signaling_pathway 10 138 0.02927 0.2509
22 hsa04350_TGF.beta_signaling_pathway 7 85 0.03498 0.2822
23 hsa04150_mTOR_signaling_pathway 5 52 0.03995 0.2822
24 hsa03320_PPAR_signaling_pathway 6 70 0.04161 0.2822
25 hsa04722_Neurotrophin_signaling_pathway 9 127 0.04223 0.2822
26 hsa04970_Salivary_secretion 7 89 0.04323 0.2822
27 hsa00410_beta.Alanine_metabolism 3 22 0.04406 0.2822
28 hsa04976_Bile_secretion 6 71 0.04412 0.2822
29 hsa04540_Gap_junction 7 90 0.04547 0.2822
30 hsa04662_B_cell_receptor_signaling_pathway 6 75 0.05507 0.3304
31 hsa04260_Cardiac_muscle_contraction 6 77 0.0611 0.3548
32 hsa04960_Aldosterone.regulated_sodium_reabsorption 4 42 0.0653 0.3673
33 hsa04142_Lysosome 8 121 0.0741 0.3753
34 hsa04962_Vasopressin.regulated_water_reabsorption 4 44 0.07491 0.3753
35 hsa04973_Carbohydrate_digestion_and_absorption 4 44 0.07491 0.3753
36 hsa04972_Pancreatic_secretion 7 101 0.07506 0.3753
37 hsa04062_Chemokine_signaling_pathway 11 189 0.08469 0.412
38 hsa00512_Mucin_type_O.Glycan_biosynthesis 3 30 0.09412 0.4284
39 hsa00520_Amino_sugar_and_nucleotide_sugar_metabolism 4 48 0.09613 0.4284
40 hsa04012_ErbB_signaling_pathway 6 87 0.0969 0.4284
41 hsa04660_T_cell_receptor_signaling_pathway 7 108 0.09865 0.4284
42 hsa04310_Wnt_signaling_pathway 9 151 0.09995 0.4284
43 hsa04720_Long.term_potentiation 5 70 0.1108 0.443
44 hsa04020_Calcium_signaling_pathway 10 177 0.1121 0.443
45 hsa04630_Jak.STAT_signaling_pathway 9 155 0.1126 0.443
46 hsa00770_Pantothenate_and_CoA_biosynthesis 2 16 0.1132 0.443
47 hsa04971_Gastric_acid_secretion 5 74 0.1316 0.4869
48 hsa04666_Fc_gamma_R.mediated_phagocytosis 6 95 0.132 0.4869
49 hsa00500_Starch_and_sucrose_metabolism 4 54 0.1325 0.4869
50 hsa00565_Ether_lipid_metabolism 3 36 0.1417 0.5034
51 hsa04370_VEGF_signaling_pathway 5 76 0.1426 0.5034
52 hsa04810_Regulation_of_actin_cytoskeleton 11 214 0.1578 0.543
53 hsa04146_Peroxisome 5 79 0.1599 0.543
54 hsa00592_alpha.Linolenic_acid_metabolism 2 20 0.1633 0.5445
55 hsa00350_Tyrosine_metabolism 3 41 0.1862 0.6093
56 hsa00532_Glycosaminoglycan_biosynthesis_._chondroitin_sulfate 2 22 0.1897 0.6096
57 hsa04964_Proximal_tubule_bicarbonate_reclamation 2 23 0.203 0.6301
58 hsa00010_Glycolysis_._Gluconeogenesis 4 65 0.2108 0.6388
59 hsa00280_Valine._leucine_and_isoleucine_degradation 3 44 0.2144 0.6388
60 hsa00760_Nicotinate_and_nicotinamide_metabolism 2 24 0.2165 0.6388
61 hsa00534_Glycosaminoglycan_biosynthesis_._heparan_sulfate 2 26 0.2436 0.696
62 hsa04730_Long.term_depression 4 70 0.2499 0.7029
63 hsa00052_Galactose_metabolism 2 27 0.2572 0.7123
64 hsa00561_Glycerolipid_metabolism 3 50 0.273 0.7447
65 hsa04916_Melanogenesis 5 101 0.3059 0.8096
66 hsa04620_Toll.like_receptor_signaling_pathway 5 102 0.313 0.8129
67 hsa04664_Fc_epsilon_RI_signaling_pathway 4 79 0.3234 0.8129
68 hsa00040_Pentose_and_glucuronate_interconversions 2 32 0.3251 0.8129
69 hsa00640_Propanoate_metabolism 2 32 0.3251 0.8129
70 hsa04514_Cell_adhesion_molecules_.CAMs. 6 136 0.3739 0.873
71 hsa04650_Natural_killer_cell_mediated_cytotoxicity 6 136 0.3739 0.873
72 hsa00230_Purine_metabolism 7 162 0.3754 0.873
73 hsa00051_Fructose_and_mannose_metabolism 2 36 0.3783 0.873
74 hsa04130_SNARE_interactions_in_vesicular_transport 2 36 0.3783 0.873
75 hsa00310_Lysine_degradation 2 44 0.4787 0.9676
76 hsa00240_Pyrimidine_metabolism 4 99 0.4872 0.9676
77 hsa04520_Adherens_junction 3 73 0.4982 0.9676
78 hsa04110_Cell_cycle 5 128 0.4993 0.9676
79 hsa04975_Fat_digestion_and_absorption 2 46 0.5022 0.9676
80 hsa00190_Oxidative_phosphorylation 5 132 0.5266 0.9972
81 hsa04530_Tight_junction 5 133 0.5333 0.9972
82 hsa04070_Phosphatidylinositol_signaling_system 3 78 0.5429 0.9972
83 hsa00564_Glycerophospholipid_metabolism 3 80 0.5602 1
84 hsa00983_Drug_metabolism_._other_enzymes 2 52 0.5685 1
85 hsa04120_Ubiquitin_mediated_proteolysis 5 139 0.5727 1
86 hsa04340_Hedgehog_signaling_pathway 2 56 0.609 1
87 hsa00590_Arachidonic_acid_metabolism 2 59 0.6375 1
88 hsa04145_Phagosome 5 156 0.674 1
89 hsa00980_Metabolism_of_xenobiotics_by_cytochrome_P450 2 71 0.7351 1
90 hsa03018_RNA_degradation 2 71 0.7351 1
91 hsa00982_Drug_metabolism_._cytochrome_P450 2 73 0.749 1
92 hsa04612_Antigen_processing_and_presentation 2 78 0.7811 1
93 hsa03008_Ribosome_biogenesis_in_eukaryotes 2 81 0.7985 1
94 hsa04974_Protein_digestion_and_absorption 2 81 0.7985 1
95 hsa04670_Leukocyte_transendothelial_migration 3 117 0.8028 1
96 hsa03015_mRNA_surveillance_pathway 2 83 0.8095 1
97 hsa04512_ECM.receptor_interaction 2 85 0.8199 1

Quest ID: af0b95c2bc31e80ebe63743b7991a6a4