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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-140-5p ABCC9 0.84 4.0E-5 -2.76 0 miRanda -0.19 0.04837 NA
2 hsa-miR-140-5p ABLIM1 0.84 4.0E-5 -1.72 0 PITA; miRanda -0.24 0.00036 NA
3 hsa-miR-140-5p ACACA 0.84 4.0E-5 -0.16 0.29248 miRanda -0.17 0 NA
4 hsa-miR-140-5p ADAM10 0.84 4.0E-5 0.67 0.00766 MirTarget; PITA; miRanda -0.12 0.04176 NA
5 hsa-miR-140-5p ADAM9 0.84 4.0E-5 -0.2 0.40665 PITA; miRanda; miRNATAP -0.21 0.00023 NA
6 hsa-miR-140-5p AGAP1 0.84 4.0E-5 -0.4 0.01021 miRanda -0.12 0.00085 NA
7 hsa-miR-140-5p AKAP11 0.84 4.0E-5 -0.8 0 MirTarget; miRanda -0.18 1.0E-5 NA
8 hsa-miR-140-5p AKAP13 0.84 4.0E-5 -1.15 0 miRanda -0.16 1.0E-5 NA
9 hsa-miR-140-5p AKAP6 0.84 4.0E-5 -3.34 0 miRanda -0.44 3.0E-5 NA
10 hsa-miR-140-5p ANK3 0.84 4.0E-5 -0.29 0.31896 miRanda -0.2 0.00341 NA
11 hsa-miR-140-5p ANKRD12 0.84 4.0E-5 -0.64 0.00012 miRanda -0.13 0.00079 NA
12 hsa-miR-140-5p ANKRD17 0.84 4.0E-5 -0.09 0.56547 miRanda -0.12 0.00072 NA
13 hsa-miR-140-5p ANKRD34A 0.84 4.0E-5 -0.41 0.07282 miRanda -0.15 0.00586 NA
14 hsa-miR-140-5p ANKS1B 0.84 4.0E-5 -3.65 0 miRanda -0.26 0.03078 NA
15 hsa-miR-140-5p ANO6 0.84 4.0E-5 -0.74 3.0E-5 miRanda -0.17 7.0E-5 NA
16 hsa-miR-140-5p ARHGAP32 0.84 4.0E-5 0.68 0.00492 miRanda -0.16 0.00502 NA
17 hsa-miR-140-5p ARHGEF4 0.84 4.0E-5 -1.44 0.0131 miRanda -0.48 0.00046 NA
18 hsa-miR-140-5p ARIH1 0.84 4.0E-5 -0.41 0.00018 MirTarget; miRanda -0.12 1.0E-5 NA
19 hsa-miR-140-5p ARMC9 0.84 4.0E-5 -0.17 0.43502 miRanda -0.13 0.01514 NA
20 hsa-miR-140-5p ARSK 0.84 4.0E-5 -0.17 0.31336 miRanda -0.1 0.01056 NA
21 hsa-miR-140-5p ASB5 0.84 4.0E-5 -6.18 0 miRanda -0.99 0 NA
22 hsa-miR-140-5p ASH1L 0.84 4.0E-5 -0.67 0.00016 miRanda -0.26 0 NA
23 hsa-miR-140-5p ASXL2 0.84 4.0E-5 -0.51 0.09339 mirMAP -0.16 0.02429 NA
24 hsa-miR-140-5p ATP9B 0.84 4.0E-5 -0.61 3.0E-5 miRanda -0.1 0.00301 NA
25 hsa-miR-140-5p BAG4 0.84 4.0E-5 0.14 0.55811 miRanda -0.16 0.00409 NA
26 hsa-miR-140-5p BAZ2B 0.84 4.0E-5 -0.74 3.0E-5 PITA; miRanda; miRNATAP -0.27 0 NA
27 hsa-miR-140-5p BBS4 0.84 4.0E-5 0.02 0.87409 miRanda -0.13 4.0E-5 NA
28 hsa-miR-140-5p BBS9 0.84 4.0E-5 -0.33 0.02266 miRanda -0.14 3.0E-5 NA
29 hsa-miR-140-5p BCHE 0.84 4.0E-5 -4.37 0 miRanda -0.52 0.00051 NA
30 hsa-miR-140-5p BCL2L2 0.84 4.0E-5 -1.27 0 PITA; miRanda; miRNATAP -0.2 0 NA
31 hsa-miR-140-5p BCL9 0.84 4.0E-5 0.12 0.4783 MirTarget; PITA; miRanda; miRNATAP -0.16 8.0E-5 NA
32 hsa-miR-140-5p BMPR1A 0.84 4.0E-5 -0.77 0 miRanda -0.2 0 NA
33 hsa-miR-140-5p BTBD7 0.84 4.0E-5 -0.3 0.03144 PITA -0.17 0 NA
34 hsa-miR-140-5p CACNA1C 0.84 4.0E-5 -2.53 0 PITA; miRNATAP -0.34 0.00027 NA
35 hsa-miR-140-5p CAMK2N1 0.84 4.0E-5 0.6 0.15571 PITA; miRanda -0.35 0.00036 NA
36 hsa-miR-140-5p CASD1 0.84 4.0E-5 -0.65 0.0001 miRNAWalker2 validate -0.11 0.0058 NA
37 hsa-miR-140-5p CAST 0.84 4.0E-5 -0.66 0.00074 miRanda -0.22 0 NA
38 hsa-miR-140-5p CBR4 0.84 4.0E-5 -0.14 0.45863 miRanda -0.11 0.01278 NA
39 hsa-miR-140-5p CCDC146 0.84 4.0E-5 -0.73 0.00616 miRanda -0.19 0.00226 NA
40 hsa-miR-140-5p CDH26 0.84 4.0E-5 0.92 0.14799 miRanda -0.3 0.04839 NA
41 hsa-miR-140-5p CDK8 0.84 4.0E-5 -0.22 0.28192 miRanda -0.15 0.00247 NA
42 hsa-miR-140-5p CDKL5 0.84 4.0E-5 -0.88 0.05367 miRanda -0.25 0.01826 NA
43 hsa-miR-140-5p CEP350 0.84 4.0E-5 -0.04 0.77047 MirTarget; miRanda -0.14 1.0E-5 NA
44 hsa-miR-140-5p CHD6 0.84 4.0E-5 -0.22 0.2394 miRanda -0.14 0.00233 NA
45 hsa-miR-140-5p CHIC1 0.84 4.0E-5 -1.03 0 miRanda -0.2 1.0E-5 NA
46 hsa-miR-140-5p CNTN1 0.84 4.0E-5 -4.98 0 PITA; miRanda -0.87 1.0E-5 NA
47 hsa-miR-140-5p CRYAB 0.84 4.0E-5 -3.8 0 miRanda -0.34 0.00352 NA
48 hsa-miR-140-5p CRYBG3 0.84 4.0E-5 -1.11 5.0E-5 miRanda -0.13 0.0437 NA
49 hsa-miR-140-5p CSDE1 0.84 4.0E-5 -0.72 0 miRanda -0.18 0 NA
50 hsa-miR-140-5p CTNNA1 0.84 4.0E-5 -0.28 0.01517 miRanda -0.12 3.0E-5 NA
51 hsa-miR-140-5p CTNNA3 0.84 4.0E-5 -1.94 0.00013 miRanda -0.25 0.03981 NA
52 hsa-miR-140-5p CTSF 0.84 4.0E-5 -1.38 0 miRanda -0.15 0.02452 NA
53 hsa-miR-140-5p CUEDC1 0.84 4.0E-5 -1.01 2.0E-5 PITA; miRanda -0.2 0.00033 NA
54 hsa-miR-140-5p CYP3A7 0.84 4.0E-5 0.59 0.34318 miRanda -0.31 0.036 NA
55 hsa-miR-140-5p CYP4F12 0.84 4.0E-5 -1.43 0.08453 miRanda -0.61 0.00165 NA
56 hsa-miR-140-5p DAAM1 0.84 4.0E-5 -0.94 0.00028 miRanda -0.3 0 NA
57 hsa-miR-140-5p DACT3 0.84 4.0E-5 -3.55 0 miRanda -0.34 0.00204 NA
58 hsa-miR-140-5p DAG1 0.84 4.0E-5 0.32 0.05698 PITA; miRanda; miRNATAP -0.12 0.00204 NA
59 hsa-miR-140-5p DDHD2 0.84 4.0E-5 -0.57 0.00195 miRanda -0.15 0.00053 NA
60 hsa-miR-140-5p DGKB 0.84 4.0E-5 -4.24 0 miRanda -0.51 0.00032 NA
61 hsa-miR-140-5p DIP2C 0.84 4.0E-5 -1.11 0 miRanda -0.19 0.00046 NA
62 hsa-miR-140-5p DIXDC1 0.84 4.0E-5 -3.01 0 miRanda -0.28 0.00062 NA
63 hsa-miR-140-5p DLG2 0.84 4.0E-5 -3.8 0 PITA; miRanda; miRNATAP -0.46 0.00014 NA
64 hsa-miR-140-5p DNAH7 0.84 4.0E-5 -0.49 0.13861 miRanda -0.22 0.0039 NA
65 hsa-miR-140-5p DNAJA4 0.84 4.0E-5 0.2 0.44006 miRanda -0.19 0.00203 NA
66 hsa-miR-140-5p DNAJC18 0.84 4.0E-5 -1.28 0 miRanda -0.12 0.01025 NA
67 hsa-miR-140-5p DNAJC27 0.84 4.0E-5 -0.9 0 miRanda -0.14 8.0E-5 NA
68 hsa-miR-140-5p DNMBP 0.84 4.0E-5 -0.9 0.00012 miRanda -0.17 0.00273 NA
69 hsa-miR-140-5p DOK6 0.84 4.0E-5 -3.8 0 mirMAP -0.34 0.00148 NA
70 hsa-miR-140-5p DST 0.84 4.0E-5 -1.12 9.0E-5 mirMAP -0.2 0.00276 NA
71 hsa-miR-140-5p DTNA 0.84 4.0E-5 -4.06 0 PITA; miRanda -0.47 0.00082 NA
72 hsa-miR-140-5p DUOX2 0.84 4.0E-5 -0.88 0.1924 miRanda; miRNATAP -0.35 0.02786 NA
73 hsa-miR-140-5p EDA 0.84 4.0E-5 -1.83 3.0E-5 miRanda -0.36 0.00059 NA
74 hsa-miR-140-5p EFCAB2 0.84 4.0E-5 -0.43 0.0619 miRanda -0.13 0.02091 NA
75 hsa-miR-140-5p EFHC2 0.84 4.0E-5 -2.73 0 miRanda -0.33 0.00983 NA
76 hsa-miR-140-5p EGFR 0.84 4.0E-5 -0.23 0.5939 miRanda -0.29 0.00422 NA
77 hsa-miR-140-5p EGLN3 0.84 4.0E-5 -0.29 0.4903 miRanda -0.4 5.0E-5 NA
78 hsa-miR-140-5p ENPP5 0.84 4.0E-5 -1.2 0.02004 miRanda -0.4 0.00117 NA
79 hsa-miR-140-5p EP300 0.84 4.0E-5 -0.26 0.13065 miRNAWalker2 validate -0.12 0.00415 NA
80 hsa-miR-140-5p EPC2 0.84 4.0E-5 -0.52 9.0E-5 miRanda -0.17 0 NA
81 hsa-miR-140-5p EPHA6 0.84 4.0E-5 -3.76 0 miRanda -0.45 0.00049 NA
82 hsa-miR-140-5p EPN2 0.84 4.0E-5 -0.46 0.00302 miRanda -0.18 0 NA
83 hsa-miR-140-5p FAM131A 0.84 4.0E-5 -0.84 0.0002 miRanda -0.12 0.031 NA
84 hsa-miR-140-5p FAM172A 0.84 4.0E-5 -1.03 0 miRanda -0.18 0 NA
85 hsa-miR-140-5p FAM179B 0.84 4.0E-5 -0.42 0.00497 miRanda -0.13 0.00015 NA
86 hsa-miR-140-5p FAM189A1 0.84 4.0E-5 -1.96 0.00881 miRanda -0.42 0.01871 NA
87 hsa-miR-140-5p FAM66D 0.84 4.0E-5 -1.4 0.03156 miRanda -0.24 0.04467 NA
88 hsa-miR-140-5p FAT1 0.84 4.0E-5 0.12 0.67443 miRanda -0.16 0.01789 NA
89 hsa-miR-140-5p FCHO2 0.84 4.0E-5 -0.44 0.00271 PITA; miRanda -0.11 0.00231 NA
90 hsa-miR-140-5p FHIT 0.84 4.0E-5 -0.65 0.11656 miRanda -0.25 0.01234 NA
91 hsa-miR-140-5p FNDC5 0.84 4.0E-5 -1.42 0.00016 PITA; miRanda -0.21 0.02077 NA
92 hsa-miR-140-5p FOXN3 0.84 4.0E-5 -1.44 0 MirTarget; PITA -0.23 0 NA
93 hsa-miR-140-5p FOXP1 0.84 4.0E-5 -0.87 0 miRanda -0.14 0.00187 NA
94 hsa-miR-140-5p FOXP2 0.84 4.0E-5 -3.99 0 MirTarget; PITA; miRanda; miRNATAP -0.54 0.00025 NA
95 hsa-miR-140-5p FRMD6 0.84 4.0E-5 -0.93 0.00183 miRanda -0.34 0 NA
96 hsa-miR-140-5p FYCO1 0.84 4.0E-5 -1.62 0 MirTarget; miRanda -0.38 0 NA
97 hsa-miR-140-5p FZD3 0.84 4.0E-5 -0.31 0.22562 miRanda -0.19 0.00178 NA
98 hsa-miR-140-5p FZD6 0.84 4.0E-5 0.39 0.09232 MirTarget; miRanda -0.14 0.01257 NA
99 hsa-miR-140-5p GBF1 0.84 4.0E-5 -0.13 0.20746 PITA; miRanda -0.1 3.0E-5 NA
100 hsa-miR-140-5p GCOM1 0.84 4.0E-5 -2.66 0 miRanda -0.67 0 NA
101 hsa-miR-140-5p GLI3 0.84 4.0E-5 -0.85 0.02024 PITA; miRanda -0.25 0.00366 NA
102 hsa-miR-140-5p GLS2 0.84 4.0E-5 0.39 0.36787 miRanda -0.27 0.00933 NA
103 hsa-miR-140-5p GLUL 0.84 4.0E-5 -0.78 0.00032 miRanda -0.1 0.04424 NA
104 hsa-miR-140-5p GNG12 0.84 4.0E-5 -1.01 0 PITA; miRanda -0.22 1.0E-5 NA
105 hsa-miR-140-5p GPD1L 0.84 4.0E-5 -1.18 0.00027 miRanda -0.16 0.04198 NA
106 hsa-miR-140-5p GPHN 0.84 4.0E-5 -0.45 0.03619 miRanda -0.21 4.0E-5 NA
107 hsa-miR-140-5p GPR135 0.84 4.0E-5 -1.48 0 miRanda -0.22 0.00144 NA
108 hsa-miR-140-5p GRIA3 0.84 4.0E-5 -2.07 7.0E-5 miRanda -0.32 0.01015 NA
109 hsa-miR-140-5p GTF2A1 0.84 4.0E-5 -0.44 0.17776 MirTarget -0.21 0.00649 NA
110 hsa-miR-140-5p GTF2IRD2 0.84 4.0E-5 -0.91 0 miRanda -0.19 7.0E-5 NA
111 hsa-miR-140-5p GTF2IRD2B 0.84 4.0E-5 -1.34 0 miRanda -0.28 1.0E-5 NA
112 hsa-miR-140-5p GTF2IRD2P1 0.84 4.0E-5 -1.27 0 miRanda -0.22 0.00023 NA
113 hsa-miR-140-5p HAND2 0.84 4.0E-5 -4.39 0 PITA; miRanda; miRNATAP -0.51 0.00025 NA
114 hsa-miR-140-5p HDAC4 0.84 4.0E-5 -1.8 0 miRNAWalker2 validate; miRTarBase; PITA; miRanda; miRNATAP -0.15 0.00404 19734943 Histone deacetylase 4 HDAC4 was confirmed to be one of the important targets of miR-140; Taken together our findings indicate that miR-140 is involved in the chemoresistance by reduced cell proliferation through G1 and G2 phase arrest mediated in part through the suppression of HDAC4 miR-140 may be a candidate target to develop novel therapeutic strategy to overcome drug resistance
115 hsa-miR-140-5p HECTD2 0.84 4.0E-5 -1.26 0 PITA; miRanda -0.16 0.00124 NA
116 hsa-miR-140-5p HMGN5 0.84 4.0E-5 -1.08 0.00139 miRanda -0.27 0.00069 NA
117 hsa-miR-140-5p HSPA4L 0.84 4.0E-5 -1.29 0.00635 PITA; miRanda -0.26 0.0205 NA
118 hsa-miR-140-5p ICK 0.84 4.0E-5 -0.46 0.0046 miRanda -0.15 7.0E-5 NA
119 hsa-miR-140-5p IDS 0.84 4.0E-5 -0.67 3.0E-5 miRanda -0.14 0.00018 NA
120 hsa-miR-140-5p IGF1R 0.84 4.0E-5 -0.49 0.0461 PITA; miRNATAP -0.21 0.00025 24039995 Integrated analysis identified IGF1R as a direct and functional target of miR-140; Knockdown of IGF1R inhibited cell proliferation and invasion resembling that of miR-140 overexpression while overexpression of IGF1R attenuated the function of miR-140 in NSCLC cells; Together our results highlight the significance of miR-140 and IGF1R in the development and progression of NSCLC
121 hsa-miR-140-5p IL20RA 0.84 4.0E-5 0.71 0.09308 miRanda -0.23 0.02137 NA
122 hsa-miR-140-5p INMT 0.84 4.0E-5 -2.76 0 miRanda -0.18 0.04678 NA
123 hsa-miR-140-5p IQCH 0.84 4.0E-5 0.3 0.17806 miRanda -0.15 0.00385 NA
124 hsa-miR-140-5p IRAK1BP1 0.84 4.0E-5 -0.29 0.15249 miRanda -0.12 0.01072 NA
125 hsa-miR-140-5p ITGA1 0.84 4.0E-5 -1.43 0 miRanda -0.17 0.02046 NA
126 hsa-miR-140-5p ITIH5 0.84 4.0E-5 -4.03 0 miRanda -0.34 0.00108 NA
127 hsa-miR-140-5p ITSN1 0.84 4.0E-5 -0.61 9.0E-5 miRanda -0.13 0.00039 NA
128 hsa-miR-140-5p KANK1 0.84 4.0E-5 -1.72 0 miRanda -0.34 0 NA
129 hsa-miR-140-5p KCNK6 0.84 4.0E-5 -0.91 0.00024 miRanda -0.26 1.0E-5 NA
130 hsa-miR-140-5p KCTD11 0.84 4.0E-5 -0.5 0.02756 miRanda -0.21 0.00011 NA
131 hsa-miR-140-5p KCTD16 0.84 4.0E-5 -0.04 0.93512 miRanda -0.32 0.00368 NA
132 hsa-miR-140-5p KCTD18 0.84 4.0E-5 -0.43 0.00118 miRanda -0.16 0 NA
133 hsa-miR-140-5p KCTD3 0.84 4.0E-5 -0.56 0.00067 miRanda -0.14 0.00045 NA
134 hsa-miR-140-5p KIAA0232 0.84 4.0E-5 -1.01 0 miRanda -0.16 1.0E-5 NA
135 hsa-miR-140-5p KIAA0586 0.84 4.0E-5 -0.37 0.02029 miRanda -0.19 0 NA
136 hsa-miR-140-5p KIAA0754 0.84 4.0E-5 -1.11 0.00843 miRanda -0.22 0.02555 NA
137 hsa-miR-140-5p KIAA1109 0.84 4.0E-5 -0.79 1.0E-5 miRanda -0.18 1.0E-5 NA
138 hsa-miR-140-5p KIF13A 0.84 4.0E-5 -1.22 0 miRanda -0.28 0 NA
139 hsa-miR-140-5p KIF1B 0.84 4.0E-5 -0.68 2.0E-5 miRanda -0.14 0.00022 NA
140 hsa-miR-140-5p KLB 0.84 4.0E-5 -0.34 0.2741 miRanda -0.16 0.0267 NA
141 hsa-miR-140-5p KLC1 0.84 4.0E-5 -0.61 0 miRanda -0.11 0.00015 NA
142 hsa-miR-140-5p KLF5 0.84 4.0E-5 0.85 0.02058 miRanda -0.22 0.01375 NA
143 hsa-miR-140-5p KRT77 0.84 4.0E-5 1.09 0.13814 miRanda -0.36 0.03999 NA
144 hsa-miR-140-5p LAMC1 0.84 4.0E-5 -0.82 0.0001 MirTarget; PITA; miRanda; miRNATAP -0.19 0.00016 NA
145 hsa-miR-140-5p LANCL3 0.84 4.0E-5 0.08 0.85028 miRanda -0.2 0.03272 NA
146 hsa-miR-140-5p LCOR 0.84 4.0E-5 -0.36 0.27591 miRNATAP -0.25 0.00147 NA
147 hsa-miR-140-5p LDB3 0.84 4.0E-5 -3.79 0 miRanda -0.35 0.00065 NA
148 hsa-miR-140-5p LEPROT 0.84 4.0E-5 -0.82 0.00547 miRanda -0.16 0.02337 NA
149 hsa-miR-140-5p LGR5 0.84 4.0E-5 0.82 0.25477 miRanda -0.47 0.00601 NA
150 hsa-miR-140-5p LGR6 0.84 4.0E-5 -2.83 0 miRanda -0.49 0.00059 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
NumGOOverlapSizeP ValueAdj. P Value
1 BETA CATENIN BINDING 10 84 1.824e-06 0.001695
2 CYTOSKELETAL PROTEIN BINDING 32 819 1.532e-05 0.004935
3 ENZYME BINDING 54 1737 1.594e-05 0.004935
NumGOOverlapSizeP ValueAdj. P Value
1 CELL JUNCTION 47 1151 3.498e-08 2.043e-05
2 CYTOSKELETON 65 1967 2.129e-07 6.216e-05
3 MEMBRANE REGION 42 1134 2.573e-06 0.0005008
4 NEURON PROJECTION 36 942 7.145e-06 0.0009841
5 CELL PROJECTION 56 1786 8.425e-06 0.0009841
6 APICAL JUNCTION COMPLEX 11 128 1.384e-05 0.001101
7 ANCHORING JUNCTION 23 489 1.509e-05 0.001101
8 PLASMA MEMBRANE REGION 35 929 1.307e-05 0.001101
9 POSTSYNAPSE 19 378 3.433e-05 0.002228
10 NODE OF RANVIER 4 15 0.0001022 0.005968
11 CELL CELL JUNCTION 18 383 0.0001291 0.006853
12 EXCITATORY SYNAPSE 12 197 0.0001681 0.007011
13 NEURON PART 40 1265 0.0001578 0.007011
14 CYTOSKELETAL PART 44 1436 0.0001475 0.007011
15 POSTSYNAPTIC MEMBRANE 12 205 0.0002431 0.009463

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Hippo_signaling_pathway_hsa04390 12 154 1.534e-05 0.0007979
2 Adherens_junction_hsa04520 8 72 3.311e-05 0.0008608
3 Focal_adhesion_hsa04510 8 199 0.0225 0.2563
4 FoxO_signaling_pathway_hsa04068 6 132 0.02706 0.2563
5 Regulation_of_actin_cytoskeleton_hsa04810 8 208 0.02832 0.2563
6 HIF_1_signaling_pathway_hsa04066 5 100 0.02957 0.2563
7 Wnt_signaling_pathway_hsa04310 6 146 0.04119 0.306
8 Endocytosis_hsa04144 8 244 0.06172 0.3687
9 Cell_cycle_hsa04110 5 124 0.06381 0.3687
10 Hippo_signaling_pathway_multiple_species_hsa04392 2 29 0.08883 0.4036
11 Apelin_signaling_pathway_hsa04371 5 137 0.08888 0.4036
12 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 5 139 0.09313 0.4036
13 Cell_adhesion_molecules_.CAMs._hsa04514 5 145 0.1065 0.426
14 mTOR_signaling_pathway_hsa04150 5 151 0.1208 0.446
15 cAMP_signaling_pathway_hsa04024 6 198 0.1286 0.446
16 Rap1_signaling_pathway_hsa04015 6 206 0.1468 0.4533
17 Jak_STAT_signaling_pathway_hsa04630 5 162 0.1491 0.4533
18 AMPK_signaling_pathway_hsa04152 4 121 0.1569 0.4533
19 ECM_receptor_interaction_hsa04512 3 82 0.1685 0.4601
20 TGF_beta_signaling_pathway_hsa04350 3 84 0.177 0.4601
21 Gap_junction_hsa04540 3 88 0.1943 0.4812
22 Calcium_signaling_pathway_hsa04020 5 182 0.2067 0.4885
23 MAPK_signaling_pathway_hsa04010 7 295 0.2487 0.5622
24 PI3K_Akt_signaling_pathway_hsa04151 8 352 0.2637 0.5713
25 cGMP_PKG_signaling_pathway_hsa04022 4 163 0.3101 0.645
26 Tight_junction_hsa04530 4 170 0.3374 0.6749
27 Lysosome_hsa04142 3 123 0.3566 0.6868
28 Ras_signaling_pathway_hsa04014 5 232 0.3715 0.69
29 ErbB_signaling_pathway_hsa04012 2 85 0.4325 0.7497
30 Phospholipase_D_signaling_pathway_hsa04072 3 146 0.4625 0.7759
31 Cellular_senescence_hsa04218 3 160 0.5233 0.8419
32 Oocyte_meiosis_hsa04114 2 124 0.6337 0.9147
33 Autophagy_animal_hsa04140 2 128 0.6509 0.9147
34 Cytokine_cytokine_receptor_interaction_hsa04060 4 270 0.6877 0.941
35 Necroptosis_hsa04217 2 164 0.7777 1
36 Neuroactive_ligand_receptor_interaction_hsa04080 2 278 0.9544 1

Quest ID: b4c9083bb378b13d6b247d3f37b01c91