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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-30c-5p ABCD2 -0.43 0.00403 -1.62 0 MirTarget -0.19 0.04591 NA
2 hsa-miR-30c-5p ABCE1 -0.43 0.00403 0.66 0 miRNAWalker2 validate -0.15 0 NA
3 hsa-miR-30c-5p ABL1 -0.43 0.00403 -0.12 0.14608 MirTarget; miRNATAP -0.1 0.00032 NA
4 hsa-miR-30c-5p ABL2 -0.43 0.00403 -0.01 0.94193 mirMAP; miRNATAP -0.14 7.0E-5 NA
5 hsa-miR-30c-5p ACAP2 -0.43 0.00403 0.87 0 MirTarget; miRNATAP -0.14 0.00513 NA
6 hsa-miR-30d-5p ACAP2 -2.07 0 0.87 0 MirTarget; miRNATAP -0.18 4.0E-5 NA
7 hsa-miR-30c-5p ACTN1 -0.43 0.00403 0.44 0.00456 miRNATAP -0.29 0 NA
8 hsa-miR-30d-5p ACTN1 -2.07 0 0.44 0.00456 miRNATAP -0.28 0 NA
9 hsa-miR-30c-5p ACVR1 -0.43 0.00403 0.36 0.00091 MirTarget; miRNATAP -0.2 0 NA
10 hsa-miR-30d-5p ACVR1 -2.07 0 0.36 0.00091 MirTarget; miRNATAP -0.17 0 NA
11 hsa-miR-30d-5p ADAM11 -2.07 0 1.92 0 miRNATAP -0.18 0.04426 NA
12 hsa-miR-30c-5p ADAM19 -0.43 0.00403 0.34 0.11219 MirTarget; miRNATAP -0.34 0 25799050 Furthermore bioinformatics algorithm and luciferase reporter assay indicated ADAM19 as a direct target of miR-30c; Of interest further experiments demonstrated that inhibition of ADAM19 by miR-30c partially mediated the anti-tumor effect of miR-30c; Overall our study provides the new insight that miR-30c inhibited colon cancer cells via targeting ADAM19
13 hsa-miR-30d-5p ADAM19 -2.07 0 0.34 0.11219 MirTarget; miRNATAP -0.32 0 NA
14 hsa-miR-30c-5p ADRA2A -0.43 0.00403 -1.31 1.0E-5 MirTarget; miRNATAP -0.21 0.03795 NA
15 hsa-miR-30d-5p AFAP1L2 -2.07 0 0.42 0.09414 MirTarget; miRNATAP -0.39 0 NA
16 hsa-miR-30c-5p AKR1C1 -0.43 0.00403 2.49 0 mirMAP -0.54 0.00274 NA
17 hsa-miR-30d-5p AKR1C1 -2.07 0 2.49 0 mirMAP -0.56 0.00058 NA
18 hsa-miR-30c-5p ALG10 -0.43 0.00403 1.21 0 MirTarget -0.16 0.0003 NA
19 hsa-miR-30d-5p ALG10 -2.07 0 1.21 0 MirTarget -0.3 0 NA
20 hsa-miR-30d-5p ALG6 -2.07 0 0.84 0 MirTarget -0.18 0 NA
21 hsa-miR-30d-5p AMMECR1 -2.07 0 1.35 0 miRNATAP -0.29 0 NA
22 hsa-miR-30d-5p ANKRD52 -2.07 0 0.72 0 miRNATAP -0.12 9.0E-5 NA
23 hsa-miR-30c-5p ANTXR1 -0.43 0.00403 -0.56 0.00196 mirMAP -0.41 0 NA
24 hsa-miR-30c-5p ANTXR2 -0.43 0.00403 -1.4 0 mirMAP -0.15 0.01982 NA
25 hsa-miR-30d-5p AP2A1 -2.07 0 0.52 0 miRNATAP -0.18 0 NA
26 hsa-miR-30d-5p ARHGAP32 -2.07 0 0.78 0 MirTarget; mirMAP -0.17 3.0E-5 NA
27 hsa-miR-30c-5p ARID3A -0.43 0.00403 0.86 0 mirMAP -0.19 6.0E-5 NA
28 hsa-miR-30d-5p ARID3A -2.07 0 0.86 0 mirMAP -0.12 0.00621 NA
29 hsa-miR-30d-5p ARL4C -2.07 0 1.08 0 miRNATAP -0.24 0 NA
30 hsa-miR-30c-5p ARL5B -0.43 0.00403 0.2 0.10264 mirMAP -0.17 4.0E-5 NA
31 hsa-miR-30d-5p ARL6IP6 -2.07 0 0.85 0 miRNATAP -0.22 0 NA
32 hsa-miR-30c-5p ASAP2 -0.43 0.00403 0.55 0 mirMAP -0.15 0.00047 NA
33 hsa-miR-30d-5p ASAP2 -2.07 0 0.55 0 mirMAP -0.15 0.0001 NA
34 hsa-miR-30c-5p ASCC3 -0.43 0.00403 0.57 0 MirTarget -0.11 0.00119 NA
35 hsa-miR-30d-5p ASCC3 -2.07 0 0.57 0 MirTarget -0.19 0 NA
36 hsa-miR-30d-5p ATAD2B -2.07 0 0.78 0 MirTarget; miRNATAP -0.1 0.0004 NA
37 hsa-miR-30c-5p ATF2 -0.43 0.00403 0.03 0.68356 mirMAP -0.1 0.00026 NA
38 hsa-miR-30d-5p ATG5 -2.07 0 0.32 0.00015 MirTarget; miRNATAP -0.11 2.0E-5 NA
39 hsa-miR-30d-5p ATL2 -2.07 0 0.79 0 miRNATAP -0.21 0 NA
40 hsa-miR-30c-5p ATL3 -0.43 0.00403 -0 0.98093 mirMAP -0.17 0.00264 NA
41 hsa-miR-30d-5p ATL3 -2.07 0 -0 0.98093 mirMAP -0.11 0.0335 NA
42 hsa-miR-30c-5p ATP2A2 -0.43 0.00403 1.05 0 mirMAP -0.19 0 NA
43 hsa-miR-30d-5p ATP2A2 -2.07 0 1.05 0 mirMAP -0.27 0 NA
44 hsa-miR-30c-5p ATP2B1 -0.43 0.00403 0.37 0.04291 MirTarget; mirMAP; miRNATAP -0.17 0.00764 NA
45 hsa-miR-30c-5p ATP8B1 -0.43 0.00403 0.69 0 miRNATAP -0.13 0.00835 NA
46 hsa-miR-30d-5p ATP8B1 -2.07 0 0.69 0 miRNATAP -0.1 0.02713 NA
47 hsa-miR-30c-5p ATP8B2 -0.43 0.00403 -0.6 0.00035 miRNATAP -0.13 0.02867 NA
48 hsa-miR-30d-5p ATR -2.07 0 0.96 0 mirMAP -0.22 0 NA
49 hsa-miR-30c-5p AVL9 -0.43 0.00403 0.9 0 MirTarget; mirMAP; miRNATAP -0.18 0 NA
50 hsa-miR-30d-5p AVL9 -2.07 0 0.9 0 MirTarget; mirMAP; miRNATAP -0.27 0 NA
51 hsa-miR-30c-5p AZIN1 -0.43 0.00403 0.54 0 mirMAP; miRNATAP -0.13 3.0E-5 NA
52 hsa-miR-30d-5p AZIN1 -2.07 0 0.54 0 miRNATAP -0.15 0 NA
53 hsa-miR-30c-5p B3GNT5 -0.43 0.00403 1.19 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.28 1.0E-5 NA
54 hsa-miR-30d-5p B3GNT5 -2.07 0 1.19 0 MirTarget; miRNATAP -0.3 0 NA
55 hsa-miR-30c-5p B4GALT1 -0.43 0.00403 0.12 0.31404 mirMAP -0.12 0.00514 NA
56 hsa-miR-30d-5p B4GALT6 -2.07 0 0.87 1.0E-5 MirTarget -0.16 0.0082 NA
57 hsa-miR-30c-5p BACH1 -0.43 0.00403 -0.34 0.00185 miRNATAP -0.12 0.00118 NA
58 hsa-miR-30c-5p BAG4 -0.43 0.00403 0.72 2.0E-5 mirMAP -0.17 0.00325 NA
59 hsa-miR-30d-5p BAG4 -2.07 0 0.72 2.0E-5 mirMAP -0.16 0.00236 NA
60 hsa-miR-30c-5p BCL11B -0.43 0.00403 1.57 0 miRNATAP -0.2 0.01879 NA
61 hsa-miR-30d-5p BCL11B -2.07 0 1.57 0 miRNATAP -0.36 0 NA
62 hsa-miR-30d-5p BCL2L11 -2.07 0 0.77 0 miRNATAP -0.19 0 NA
63 hsa-miR-30d-5p BCL9 -2.07 0 0.8 0 miRNATAP -0.18 0 NA
64 hsa-miR-30d-5p BEND3 -2.07 0 1.04 0 mirMAP; miRNATAP -0.21 0 NA
65 hsa-miR-30c-5p BICD1 -0.43 0.00403 0.8 0 mirMAP -0.22 3.0E-5 NA
66 hsa-miR-30d-5p BICD1 -2.07 0 0.8 0 mirMAP -0.27 0 NA
67 hsa-miR-30c-5p BIRC5 -0.43 0.00403 5.23 0 miRNAWalker2 validate -0.4 0.00025 NA
68 hsa-miR-30c-5p BLMH -0.43 0.00403 0.93 0 miRNAWalker2 validate -0.14 0.01515 NA
69 hsa-miR-30c-5p BMP7 -0.43 0.00403 3.61 0 mirMAP; miRNATAP -0.28 0.04166 NA
70 hsa-miR-30d-5p BMP7 -2.07 0 3.61 0 mirMAP; miRNATAP -0.84 0 NA
71 hsa-miR-30c-5p BNC1 -0.43 0.00403 5.3 0 MirTarget; miRNATAP -0.48 0.00638 NA
72 hsa-miR-30d-5p BNC1 -2.07 0 5.3 0 MirTarget; miRNATAP -1.42 0 NA
73 hsa-miR-30c-5p BNC2 -0.43 0.00403 -1.29 0 mirMAP; miRNATAP -0.32 0.00022 NA
74 hsa-miR-30c-5p BRD4 -0.43 0.00403 0.62 0 mirMAP -0.16 1.0E-5 NA
75 hsa-miR-30d-5p BRD4 -2.07 0 0.62 0 mirMAP -0.13 9.0E-5 NA
76 hsa-miR-30d-5p BRWD3 -2.07 0 0.69 0 MirTarget; miRNATAP -0.11 0.01992 NA
77 hsa-miR-30c-5p BTBD10 -0.43 0.00403 0.7 0 MirTarget; miRNATAP -0.1 0.00693 NA
78 hsa-miR-30d-5p BTBD10 -2.07 0 0.7 0 MirTarget; miRNATAP -0.22 0 NA
79 hsa-miR-30d-5p C16orf87 -2.07 0 0.78 0 miRNATAP -0.21 0 NA
80 hsa-miR-30c-5p C1QBP -0.43 0.00403 0.97 0 miRNAWalker2 validate -0.16 0.00036 NA
81 hsa-miR-30c-5p C21orf91 -0.43 0.00403 0.57 0.0004 mirMAP -0.12 0.03733 NA
82 hsa-miR-30d-5p C21orf91 -2.07 0 0.57 0.0004 mirMAP -0.15 0.00428 NA
83 hsa-miR-30c-5p C4orf46 -0.43 0.00403 0.91 0 mirMAP -0.13 0.00135 NA
84 hsa-miR-30d-5p C4orf46 -2.07 0 0.91 0 mirMAP -0.23 0 NA
85 hsa-miR-30c-5p C6orf132 -0.43 0.00403 0.58 0.00071 mirMAP -0.17 0.00417 NA
86 hsa-miR-30d-5p C6orf132 -2.07 0 0.58 0.00071 mirMAP -0.16 0.00221 NA
87 hsa-miR-30d-5p C7orf43 -2.07 0 0.79 0 miRNATAP -0.16 0 NA
88 hsa-miR-30c-5p CALU -0.43 0.00403 0.75 0 MirTarget -0.25 0 NA
89 hsa-miR-30d-5p CALU -2.07 0 0.75 0 MirTarget -0.25 0 NA
90 hsa-miR-30c-5p CAND1 -0.43 0.00403 0.85 0 mirMAP -0.13 0.00015 NA
91 hsa-miR-30d-5p CAND1 -2.07 0 0.85 0 mirMAP -0.21 0 NA
92 hsa-miR-30d-5p CAPZA1 -2.07 0 0.28 0.00102 MirTarget; miRNATAP -0.12 1.0E-5 NA
93 hsa-miR-30d-5p CARS -2.07 0 0.58 0 MirTarget; miRNATAP -0.19 0 NA
94 hsa-miR-30c-5p CASP3 -0.43 0.00403 0.86 0 miRNATAP -0.14 5.0E-5 NA
95 hsa-miR-30d-5p CASP3 -2.07 0 0.86 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.24 0 NA
96 hsa-miR-30c-5p CBFB -0.43 0.00403 0.45 0 MirTarget; mirMAP; miRNATAP -0.14 0 NA
97 hsa-miR-30d-5p CBFB -2.07 0 0.45 0 MirTarget; mirMAP; miRNATAP -0.21 0 NA
98 hsa-miR-30d-5p CBLB -2.07 0 0.65 0 MirTarget; mirMAP -0.17 1.0E-5 NA
99 hsa-miR-30c-5p CBX2 -0.43 0.00403 3.27 0 miRNATAP -0.38 0.00011 NA
100 hsa-miR-30d-5p CBX2 -2.07 0 3.27 0 miRNATAP -0.8 0 NA
101 hsa-miR-30d-5p CBX3 -2.07 0 1.09 0 MirTarget -0.29 0 NA
102 hsa-miR-30c-5p CCDC117 -0.43 0.00403 0.53 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.13 0.00014 NA
103 hsa-miR-30d-5p CCDC117 -2.07 0 0.53 0 MirTarget; miRNATAP -0.12 0.00016 NA
104 hsa-miR-30d-5p CCDC43 -2.07 0 0.56 0 MirTarget -0.15 0 NA
105 hsa-miR-30d-5p CCNA1 -2.07 0 0.88 0.09811 MirTarget -0.37 0.02913 NA
106 hsa-miR-30c-5p CCNE2 -0.43 0.00403 2.53 0 miRNATAP -0.21 0.00294 NA
107 hsa-miR-30d-5p CCNE2 -2.07 0 2.53 0 miRNATAP -0.54 0 25843294 MicroRNA 30d 5p inhibits tumour cell proliferation and motility by directly targeting CCNE2 in non small cell lung cancer; In addition the re-introduction of CCNE2 expression antagonised the inhibitory effects of miR-30d-5p on the capacity of NSCLC cells for proliferation and motility
108 hsa-let-7a-5p CCNF -0.64 0 2.78 0 MirTarget; TargetScan -0.68 0 NA
109 hsa-let-7b-5p CCNF -0.76 0 2.78 0 miRNAWalker2 validate; MirTarget -0.4 0 NA
110 hsa-let-7c-5p CCNF -1.1 0 2.78 0 miRNAWalker2 validate; MirTarget -0.19 7.0E-5 NA
111 hsa-miR-139-5p CCNF -2.26 0 2.78 0 miRanda -0.43 0 NA
112 hsa-miR-140-5p CCNF -0.62 0 2.78 0 miRanda -0.44 0 NA
113 hsa-miR-34c-3p CCNF -1.49 4.0E-5 2.78 0 mirMAP -0.11 1.0E-5 NA
114 hsa-miR-30c-5p CCPG1 -0.43 0.00403 -1.19 0 miRNATAP -0.1 0.02981 NA
115 hsa-miR-30d-5p CDCA7 -2.07 0 3.7 0 MirTarget -0.86 0 NA
116 hsa-miR-30c-5p CDH1 -0.43 0.00403 1.16 0 miRNAWalker2 validate -0.16 0.00213 24112779 Repression of miR-30c through its inhibitor resulted in reduction of E-cadherin production and promotion of epithelial-mesenchymal transition EMT while overexpression of miR-30c inhibited EMT in RCC cells; Our findings propose a model that hypoxia induces EMT in RCC cells through downregulation of miR-30c which leads to subsequent increase of Slug expression and repression of E-cadherin production and suggest a potential application of miR-30c in RCC treatment
117 hsa-miR-30c-5p CDH13 -0.43 0.00403 -1.14 0.00013 miRNATAP -0.38 0.00022 NA
118 hsa-miR-30d-5p CDH8 -2.07 0 2.35 0 mirMAP -0.59 1.0E-5 NA
119 hsa-miR-30c-5p CDK12 -0.43 0.00403 0.51 0 MirTarget; miRNATAP -0.12 7.0E-5 NA
120 hsa-miR-30d-5p CDK12 -2.07 0 0.51 0 MirTarget; miRNATAP -0.11 5.0E-5 NA
121 hsa-miR-30c-5p CDK6 -0.43 0.00403 1.06 0 mirMAP -0.15 0.01225 NA
122 hsa-miR-30d-5p CDK6 -2.07 0 1.06 0 mirMAP -0.3 0 NA
123 hsa-miR-30d-5p CELSR3 -2.07 0 2.2 0 MirTarget; miRNATAP -0.4 0 NA
124 hsa-miR-30c-5p CEP76 -0.43 0.00403 1.09 0 MirTarget -0.19 1.0E-5 NA
125 hsa-miR-30d-5p CEP76 -2.07 0 1.09 0 MirTarget -0.21 0 NA
126 hsa-miR-30c-5p CHRM3 -0.43 0.00403 1.64 0 mirMAP -0.26 0.01782 NA
127 hsa-miR-30d-5p CHST1 -2.07 0 0.3 0.25431 MirTarget -0.17 0.04171 NA
128 hsa-miR-30d-5p CHST2 -2.07 0 1.23 1.0E-5 MirTarget; miRNATAP -0.33 0.00018 NA
129 hsa-miR-30c-5p CIT -0.43 0.00403 0.96 0 miRNATAP -0.1 0.0373 NA
130 hsa-miR-30d-5p CIT -2.07 0 0.96 0 miRNATAP -0.16 0.0003 NA
131 hsa-miR-30c-5p CKAP4 -0.43 0.00403 1.53 0 miRNAWalker2 validate -0.21 1.0E-5 NA
132 hsa-miR-30d-5p CLDN12 -2.07 0 0.43 7.0E-5 mirMAP -0.15 1.0E-5 NA
133 hsa-miR-30d-5p CLDND1 -2.07 0 0.87 0 MirTarget; miRNATAP -0.19 0 NA
134 hsa-miR-30c-5p CLOCK -0.43 0.00403 -0.07 0.61101 MirTarget -0.2 2.0E-5 NA
135 hsa-miR-30c-5p CLTC -0.43 0.00403 0.2 0.0074 mirMAP -0.17 0 NA
136 hsa-miR-30d-5p CLTC -2.07 0 0.2 0.0074 mirMAP -0.1 1.0E-5 NA
137 hsa-miR-30d-5p COG2 -2.07 0 0.32 3.0E-5 miRNATAP -0.1 1.0E-5 NA
138 hsa-miR-30c-5p COL12A1 -0.43 0.00403 0.1 0.74262 mirMAP -0.65 0 NA
139 hsa-miR-30d-5p COL12A1 -2.07 0 0.1 0.74262 mirMAP -0.44 0 NA
140 hsa-miR-30c-5p COL8A1 -0.43 0.00403 -1.62 0 MirTarget -0.49 0 NA
141 hsa-miR-30d-5p COL9A3 -2.07 0 2.72 0 MirTarget -0.58 1.0E-5 NA
142 hsa-miR-30d-5p COPS2 -2.07 0 0.35 1.0E-5 mirMAP -0.12 0 NA
143 hsa-miR-30d-5p COPS7A -2.07 0 0.56 0 miRNAWalker2 validate -0.19 0 NA
144 hsa-miR-30d-5p COPS7B -2.07 0 0.7 0 mirMAP -0.14 0 NA
145 hsa-miR-30c-5p CPD -0.43 0.00403 0.23 0.05807 mirMAP -0.16 0.00011 NA
146 hsa-miR-30c-5p CPSF2 -0.43 0.00403 0.47 0 mirMAP -0.13 2.0E-5 NA
147 hsa-miR-30d-5p CPSF6 -2.07 0 0.87 0 MirTarget; miRNATAP -0.15 0 NA
148 hsa-miR-30c-5p CRK -0.43 0.00403 -0.63 0 miRNATAP -0.17 0 NA
149 hsa-miR-30c-5p CRKL -0.43 0.00403 0.92 0 MirTarget; mirMAP; miRNATAP -0.11 0.0086 NA
150 hsa-miR-30d-5p CRKL -2.07 0 0.92 0 MirTarget; mirMAP; miRNATAP -0.23 0 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 128 1784 1.085e-17 5.048e-14
2 CELL DEVELOPMENT 108 1426 1.573e-16 3.66e-13
3 TISSUE DEVELOPMENT 110 1518 1.748e-15 2.712e-12
4 POSITIVE REGULATION OF GENE EXPRESSION 118 1733 1.225e-14 1.425e-11
5 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 81 1004 5.629e-14 5.238e-11
6 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 119 1805 9.031e-14 7.003e-11
7 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 64 724 5.77e-13 3.835e-10
8 EPITHELIUM DEVELOPMENT 73 945 8.987e-12 5.042e-09
9 NEUROGENESIS 95 1402 9.752e-12 5.042e-09
10 NEURON DIFFERENTIATION 68 874 3.611e-11 1.68e-08
11 EMBRYO DEVELOPMENT 68 894 9.708e-11 4.107e-08
12 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 71 957 1.105e-10 4.284e-08
13 EMBRYONIC MORPHOGENESIS 49 539 1.314e-10 4.702e-08
14 HEAD DEVELOPMENT 58 709 1.633e-10 5.426e-08
15 TISSUE MORPHOGENESIS 48 533 2.813e-10 8.726e-08
16 MORPHOGENESIS OF AN EPITHELIUM 40 400 4.326e-10 1.258e-07
17 CENTRAL NERVOUS SYSTEM DEVELOPMENT 65 872 5.97e-10 1.634e-07
18 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 94 1517 1.502e-09 3.882e-07
19 TUBE DEVELOPMENT 47 552 2.7e-09 6.613e-07
20 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 56 740 5.85e-09 1.361e-06
21 NEGATIVE REGULATION OF GENE EXPRESSION 91 1493 6.403e-09 1.419e-06
22 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 46 554 8.756e-09 1.852e-06
23 ORGAN MORPHOGENESIS 60 841 1.448e-08 2.93e-06
24 NEURON DEVELOPMENT 52 687 2.085e-08 3.824e-06
25 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 43 513 2.062e-08 3.824e-06
26 EPITHELIAL CELL DIFFERENTIATION 42 495 2.137e-08 3.824e-06
27 MORPHOGENESIS OF A BRANCHING STRUCTURE 22 167 3.116e-08 5e-06
28 TUBE MORPHOGENESIS 32 323 3.079e-08 5e-06
29 CELLULAR RESPONSE TO STRESS 92 1565 2.975e-08 5e-06
30 MITOTIC CELL CYCLE 55 766 4.835e-08 7.5e-06
31 CELL PROLIFERATION 50 672 6.749e-08 1.013e-05
32 REGULATION OF CELLULAR RESPONSE TO STRESS 50 691 1.595e-07 2.319e-05
33 APPENDAGE DEVELOPMENT 21 169 1.764e-07 2.414e-05
34 LIMB DEVELOPMENT 21 169 1.764e-07 2.414e-05
35 REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 9 29 2.343e-07 3.029e-05
36 POSITIVE REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 9 29 2.343e-07 3.029e-05
37 CELL CYCLE 78 1316 2.757e-07 3.467e-05
38 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 18 134 4.132e-07 5.06e-05
39 CELL CYCLE PROCESS 67 1081 4.294e-07 5.123e-05
40 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 64 1021 5.376e-07 6.254e-05
41 FORMATION OF PRIMARY GERM LAYER 16 110 6.082e-07 6.738e-05
42 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 92 1672 5.976e-07 6.738e-05
43 PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 57 873 6.47e-07 7.001e-05
44 UROGENITAL SYSTEM DEVELOPMENT 28 299 7.084e-07 7.491e-05
45 REGULATION OF CELL DIFFERENTIATION 84 1492 7.852e-07 8.119e-05
46 REGULATION OF CELL DEATH 83 1472 8.662e-07 8.762e-05
47 PROTEASOMAL PROTEIN CATABOLIC PROCESS 26 271 1.116e-06 0.0001105
48 STEM CELL DIFFERENTIATION 21 190 1.257e-06 0.0001219
49 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 17 131 1.411e-06 0.000134
50 REGULATION OF ORGAN MORPHOGENESIS 24 242 1.6e-06 0.0001489
51 MITOCHONDRIAL MEMBRANE ORGANIZATION 14 92 1.757e-06 0.0001574
52 REGULATION OF CELLULAR COMPONENT MOVEMENT 51 771 1.769e-06 0.0001574
53 POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 9 36 1.793e-06 0.0001574
54 EMBRYONIC ORGAN DEVELOPMENT 33 406 1.828e-06 0.0001575
55 NEURON PROJECTION DEVELOPMENT 40 545 2.005e-06 0.0001696
56 GROWTH 33 410 2.263e-06 0.0001847
57 MORPHOGENESIS OF A POLARIZED EPITHELIUM 8 28 2.256e-06 0.0001847
58 PROTEIN LOCALIZATION 95 1805 2.653e-06 0.0002096
59 REGULATION OF MEMBRANE PERMEABILITY 12 70 2.658e-06 0.0002096
60 SENSORY ORGAN DEVELOPMENT 37 493 2.907e-06 0.0002254
61 SYMPATHETIC NERVOUS SYSTEM DEVELOPMENT 7 21 3.11e-06 0.0002334
62 REGULATION OF CELL PROLIFERATION 82 1496 3.07e-06 0.0002334
63 CARDIOVASCULAR SYSTEM DEVELOPMENT 51 788 3.302e-06 0.00024
64 CIRCULATORY SYSTEM DEVELOPMENT 51 788 3.302e-06 0.00024
65 EPITHELIAL CELL DEVELOPMENT 20 186 3.435e-06 0.0002422
66 INTRACELLULAR SIGNAL TRANSDUCTION 85 1572 3.393e-06 0.0002422
67 REGULATION OF CELL DEVELOPMENT 53 836 3.851e-06 0.0002675
68 MESENCHYME DEVELOPMENT 20 190 4.76e-06 0.0003257
69 TUBE FORMATION 16 129 5.211e-06 0.0003514
70 HEART DEVELOPMENT 35 466 5.296e-06 0.000352
71 DEVELOPMENTAL GROWTH 28 333 5.809e-06 0.0003807
72 CELL FATE COMMITMENT 22 227 6.276e-06 0.0004056
73 MEMBRANE ORGANIZATION 55 899 7.176e-06 0.0004574
74 CELLULAR COMPONENT MORPHOGENESIS 55 900 7.411e-06 0.000466
75 REGULATION OF CELL CYCLE 57 949 8.402e-06 0.0005213
76 MESENCHYMAL CELL DIFFERENTIATION 16 134 8.544e-06 0.0005231
77 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 71 1275 8.842e-06 0.0005275
78 REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 9 43 8.745e-06 0.0005275
79 MESODERM MORPHOGENESIS 11 66 9.181e-06 0.0005407
80 PEPTIDYL AMINO ACID MODIFICATION 52 841 9.597e-06 0.0005582
81 CELLULAR MACROMOLECULE LOCALIZATION 69 1234 1.043e-05 0.0005993
82 REGULATION OF APOPTOTIC SIGNALING PATHWAY 29 363 1.066e-05 0.0006048
83 NEURON PROJECTION MORPHOGENESIS 31 402 1.082e-05 0.0006066
84 ESTABLISHMENT OF TISSUE POLARITY 6 17 1.115e-05 0.0006177
85 PROTEIN UBIQUITINATION 42 629 1.174e-05 0.0006428
86 NEGATIVE REGULATION OF CELL DEATH 53 872 1.269e-05 0.0006867
87 LUNG MORPHOGENESIS 9 45 1.296e-05 0.0006931
88 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 29 368 1.381e-05 0.00073
89 GASTRULATION 17 155 1.413e-05 0.0007387
90 MESODERMAL CELL DIFFERENTIATION 7 26 1.525e-05 0.0007883
91 WNT SIGNALING PATHWAY 28 351 1.549e-05 0.0007921
92 CELL CYCLE G1 S PHASE TRANSITION 14 111 1.652e-05 0.0008093
93 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 28 352 1.632e-05 0.0008093
94 G1 S TRANSITION OF MITOTIC CELL CYCLE 14 111 1.652e-05 0.0008093
95 CELL PROJECTION ORGANIZATION 54 902 1.602e-05 0.0008093
96 REGULATION OF NEURON DIFFERENTIATION 38 554 1.694e-05 0.000821
97 PROTEIN POLYUBIQUITINATION 22 243 1.847e-05 0.0008726
98 EMBRYONIC ORGAN MORPHOGENESIS 24 279 1.833e-05 0.0008726
99 GOLGI ORGANIZATION 12 84 1.857e-05 0.0008726
100 PROTEIN CATABOLIC PROCESS 39 579 1.981e-05 0.0009052
101 SKELETAL SYSTEM DEVELOPMENT 33 455 2.004e-05 0.0009052
102 GLAND DEVELOPMENT 30 395 2.001e-05 0.0009052
103 REGULATION OF CELL CYCLE PROCESS 38 558 1.986e-05 0.0009052
104 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 98 1977 2.205e-05 0.0009864
105 CONNECTIVE TISSUE DEVELOPMENT 19 194 2.29e-05 0.001015
106 POSITIVE REGULATION OF CELL COMMUNICATION 80 1532 2.372e-05 0.001041
107 BIOLOGICAL ADHESION 59 1032 2.506e-05 0.00109
108 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 64 1152 2.705e-05 0.001165
109 CARTILAGE DEVELOPMENT 16 147 2.761e-05 0.001179
110 ENDOMEMBRANE SYSTEM ORGANIZATION 33 465 3.095e-05 0.001309
111 NEURAL TUBE DEVELOPMENT 16 149 3.264e-05 0.001356
112 ASTROCYTE DIFFERENTIATION 8 39 3.245e-05 0.001356
113 EPITHELIAL CELL PROLIFERATION 12 89 3.36e-05 0.001383
114 REPRODUCTIVE SYSTEM DEVELOPMENT 30 408 3.674e-05 0.001487
115 VASCULATURE DEVELOPMENT 33 469 3.667e-05 0.001487
116 IN UTERO EMBRYONIC DEVELOPMENT 25 311 3.856e-05 0.001547
117 ODONTOGENESIS 13 105 4.012e-05 0.001596
118 CELL JUNCTION ORGANIZATION 18 185 4.074e-05 0.001606
119 MUSCLE TISSUE DEVELOPMENT 23 275 4.233e-05 0.001655
120 POSITIVE REGULATION OF CELL DIFFERENTIATION 49 823 4.575e-05 0.001774
121 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 39 602 4.677e-05 0.001799
122 NEURON PROJECTION GUIDANCE 19 205 4.912e-05 0.001873
123 POSITIVE REGULATION OF CELL DEATH 39 605 5.208e-05 0.00197
124 REGULATION OF ORGANELLE ORGANIZATION 64 1178 5.26e-05 0.001974
125 PROTEIN PHOSPHORYLATION 54 944 5.492e-05 0.002045
126 AUTONOMIC NERVOUS SYSTEM DEVELOPMENT 8 42 5.708e-05 0.002108
127 NEURAL TUBE FORMATION 12 94 5.822e-05 0.002133
128 POSITIVE REGULATION OF NEURON DEATH 10 67 6.257e-05 0.002275
129 LOCOMOTION 61 1114 6.357e-05 0.002293
130 REGULATION OF CELL AGING 7 33 8.107e-05 0.002902
131 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION 14 128 8.195e-05 0.002911
132 EYE DEVELOPMENT 25 326 8.276e-05 0.002917
133 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 16 162 9.001e-05 0.003149
134 NEGATIVE REGULATION OF CELL PROLIFERATION 40 643 9.075e-05 0.003151
135 RESPIRATORY SYSTEM DEVELOPMENT 18 197 9.251e-05 0.003189
136 REGULATION OF NEURON DEATH 21 252 9.483e-05 0.003245
137 POSITIVE REGULATION OF CELL DEVELOPMENT 32 472 9.653e-05 0.003279
138 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 18 199 0.0001053 0.00355
139 CELL CYCLE PHASE TRANSITION 21 255 0.0001121 0.003736
140 PEPTIDYL THREONINE MODIFICATION 8 46 0.0001124 0.003736
141 REGULATION OF PROTEIN MODIFICATION PROCESS 84 1710 0.000124 0.004093
142 DNA TEMPLATED TRANSCRIPTION INITIATION 18 202 0.0001274 0.004174
143 THYMUS DEVELOPMENT 8 47 0.0001316 0.004282
144 POSITIVE REGULATION OF CELL PROLIFERATION 47 814 0.0001349 0.004347
145 MESODERM DEVELOPMENT 13 118 0.0001355 0.004347
146 FOREBRAIN DEVELOPMENT 26 357 0.0001393 0.004414
147 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 9 60 0.0001394 0.004414
148 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 44 750 0.0001551 0.004853
149 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 12 104 0.0001565 0.004853
150 REPRODUCTION 67 1297 0.0001559 0.004853
151 REGULATION OF CELLULAR SENESCENCE 6 26 0.0001612 0.004901
152 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 15 153 0.0001607 0.004901
153 TRANSCRIPTION INITIATION FROM RNA POLYMERASE II PROMOTER 15 153 0.0001607 0.004901
154 POSITIVE REGULATION OF RESPONSE TO STIMULUS 92 1929 0.0001639 0.004952
155 ODONTOGENESIS OF DENTIN CONTAINING TOOTH 10 75 0.0001653 0.004962
156 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 16 171 0.0001698 0.005065
157 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 18 207 0.0001733 0.005071
158 PHOSPHORYLATION 64 1228 0.0001723 0.005071
159 REGULATION OF CELL MORPHOGENESIS 35 552 0.0001719 0.005071
160 TELENCEPHALON DEVELOPMENT 19 228 0.0002011 0.005849
161 REGULATION OF CARTILAGE DEVELOPMENT 9 63 0.0002046 0.005912
162 ENDOCRINE SYSTEM DEVELOPMENT 13 123 0.000206 0.005916
163 MACROMOLECULE CATABOLIC PROCESS 51 926 0.0002229 0.006364
164 POST ANAL TAIL MORPHOGENESIS 5 18 0.0002261 0.006415
165 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 11 93 0.000234 0.006598
166 HOMOTYPIC CELL CELL ADHESION 8 51 0.0002375 0.006616
167 CELL CYCLE CHECKPOINT 17 194 0.0002373 0.006616
168 REGULATION OF RESPONSE TO STRESS 73 1468 0.0002482 0.006796
169 COCHLEA DEVELOPMENT 7 39 0.000246 0.006796
170 NEGATIVE REGULATION OF CELL CYCLE 29 433 0.0002483 0.006796
171 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 70 1395 0.0002586 0.007037
172 OSTEOBLAST DIFFERENTIATION 13 126 0.0002618 0.007063
173 NEGATIVE REGULATION OF CELL DIFFERENTIATION 37 609 0.0002626 0.007063
174 REGULATION OF ESTABLISHMENT OF PLANAR POLARITY 12 110 0.0002664 0.007123
175 EPIDERMIS DEVELOPMENT 20 253 0.0002786 0.007408
176 PROTEIN COMPLEX SUBUNIT ORGANIZATION 75 1527 0.0002947 0.00779
177 METANEPHROS DEVELOPMENT 10 81 0.0003141 0.008229
178 PATTERN SPECIFICATION PROCESS 28 418 0.0003148 0.008229
179 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 14 146 0.000331 0.008508
180 CELL AGING 9 67 0.0003289 0.008508
181 CELL JUNCTION ASSEMBLY 13 129 0.0003301 0.008508
182 PROSTATE GLAND DEVELOPMENT 7 41 0.0003397 0.008686
183 CARBOHYDRATE DERIVATIVE BIOSYNTHETIC PROCESS 36 595 0.0003424 0.008706
184 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 24 337 0.0003449 0.008721
185 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 14 147 0.000355 0.008929
186 SENSORY ORGAN MORPHOGENESIS 19 239 0.0003656 0.009145
187 EMBRYONIC PLACENTA DEVELOPMENT 10 83 0.0003835 0.009478
188 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 15 166 0.0003911 0.009478
189 TRACHEA DEVELOPMENT 5 20 0.0003875 0.009478
190 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 59 1142 0.0003875 0.009478
191 REGULATION OF INTRACELLULAR TRANSPORT 37 621 0.0003815 0.009478
192 REGULATION OF PHOSPHORUS METABOLIC PROCESS 78 1618 0.0003907 0.009478
193 REGULATION OF KIDNEY DEVELOPMENT 8 55 0.0004047 0.009756
NumGOOverlapSizeP ValueAdj. P Value
1 MACROMOLECULAR COMPLEX BINDING 99 1399 2.478e-13 2.302e-10
2 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 58 629 1.336e-12 6.204e-10
3 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 38 315 4.714e-12 1.46e-09
4 REGULATORY REGION NUCLEIC ACID BINDING 64 818 1.131e-10 2.101e-08
5 SEQUENCE SPECIFIC DNA BINDING 75 1037 1.026e-10 2.101e-08
6 DOUBLE STRANDED DNA BINDING 60 764 3.883e-10 6.012e-08
7 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 79 1199 2.449e-09 3.251e-07
8 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 32 328 4.422e-08 5.135e-06
9 PROTEIN COMPLEX BINDING 62 935 1.18e-07 1.137e-05
10 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 25 226 1.223e-07 1.137e-05
11 ENZYME BINDING 96 1737 2.67e-07 2.255e-05
12 CHROMATIN BINDING 36 435 4.044e-07 3.131e-05
13 CORE PROMOTER BINDING 19 152 6.163e-07 4.404e-05
14 PROTEIN DOMAIN SPECIFIC BINDING 44 624 1.79e-06 0.0001188
15 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 41 588 5.312e-06 0.000329
16 RIBONUCLEOTIDE BINDING 95 1860 9.197e-06 0.000534
17 KINASE BINDING 40 606 2.463e-05 0.001346
18 ADENYL NUCLEOTIDE BINDING 79 1514 2.751e-05 0.00142
19 CORE PROMOTER PROXIMAL REGION DNA BINDING 28 371 4.198e-05 0.002053
20 CYTOSKELETAL PROTEIN BINDING 48 819 8.02e-05 0.003725
21 IDENTICAL PROTEIN BINDING 64 1209 0.0001113 0.004924
22 ACTIN MONOMER BINDING 6 25 0.0001275 0.005231
23 TRANSCRIPTION COACTIVATOR ACTIVITY 23 296 0.0001295 0.005231
24 POLY A RNA BINDING 62 1170 0.0001389 0.005375
25 KINASE ACTIVITY 48 842 0.0001547 0.005748
26 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 54 992 0.0001954 0.006982
27 PROTEIN KINASE C BINDING 8 50 0.0002061 0.00709
NumGOOverlapSizeP ValueAdj. P Value
1 ANCHORING JUNCTION 43 489 5.032e-09 2.939e-06
2 CELL JUNCTION 73 1151 5.007e-08 9.746e-06
3 CELL SUBSTRATE JUNCTION 36 398 4.485e-08 9.746e-06
4 TRANSCRIPTION FACTOR COMPLEX 27 298 2.108e-06 0.0003077
5 CATALYTIC COMPLEX 62 1038 3.963e-06 0.0004628
6 TRANSFERASE COMPLEX 44 703 3.524e-05 0.00343
7 GOLGI APPARATUS 75 1445 5.31e-05 0.00443

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Cellular_senescence_hsa04218 20 160 3.133e-07 1.629e-05
2 ErbB_signaling_pathway_hsa04012 11 85 0.0001038 0.00265
3 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 14 139 0.0001984 0.00265
4 Cell_cycle_hsa04110 13 124 0.0002233 0.00265
5 PI3K_Akt_signaling_pathway_hsa04151 25 352 0.0002727 0.00265
6 Autophagy_animal_hsa04140 13 128 0.0003058 0.00265
7 mTOR_signaling_pathway_hsa04150 14 151 0.0004667 0.002959
8 Sphingolipid_signaling_pathway_hsa04071 12 118 0.0005095 0.002959
9 Regulation_of_actin_cytoskeleton_hsa04810 17 208 0.0005342 0.002959
10 Hippo_signaling_pathway_hsa04390 14 154 0.000569 0.002959
11 MAPK_signaling_pathway_hsa04010 21 295 0.0007947 0.003757
12 cGMP_PKG_signaling_pathway_hsa04022 14 163 0.000997 0.004289
13 Wnt_signaling_pathway_hsa04310 13 146 0.001072 0.004289
14 FoxO_signaling_pathway_hsa04068 12 132 0.001377 0.005115
15 p53_signaling_pathway_hsa04115 8 68 0.001692 0.005866
16 Adherens_junction_hsa04520 8 72 0.002444 0.007943
17 Endocytosis_hsa04144 17 244 0.003017 0.009228
18 Focal_adhesion_hsa04510 14 199 0.006213 0.01795
19 AMPK_signaling_pathway_hsa04152 10 121 0.006596 0.01805
20 Rap1_signaling_pathway_hsa04015 14 206 0.008329 0.02166
21 VEGF_signaling_pathway_hsa04370 6 59 0.01266 0.03135
22 Apoptosis_hsa04210 10 138 0.01579 0.03732
23 TGF_beta_signaling_pathway_hsa04350 7 84 0.02048 0.04594
24 Oocyte_meiosis_hsa04114 9 124 0.0212 0.04594
25 Apoptosis_multiple_species_hsa04215 4 33 0.02219 0.04616
26 Ferroptosis_hsa04216 4 40 0.04147 0.08295
27 HIF_1_signaling_pathway_hsa04066 7 100 0.0466 0.08974
28 Tight_junction_hsa04530 10 170 0.0544 0.101
29 Mitophagy_animal_hsa04137 5 65 0.06217 0.1115
30 TNF_signaling_pathway_hsa04668 7 108 0.06525 0.1131
31 Ras_signaling_pathway_hsa04014 12 232 0.08184 0.1373
32 cAMP_signaling_pathway_hsa04024 10 198 0.1183 0.1923
33 Hedgehog_signaling_pathway_hsa04340 3 47 0.2001 0.3138
34 Phospholipase_D_signaling_pathway_hsa04072 7 146 0.2052 0.3138
35 Phosphatidylinositol_signaling_system_hsa04070 5 99 0.2261 0.3359
36 Hippo_signaling_pathway_multiple_species_hsa04392 2 29 0.2465 0.356
37 ECM_receptor_interaction_hsa04512 4 82 0.2832 0.398
38 Apelin_signaling_pathway_hsa04371 6 137 0.2954 0.4042
39 Gap_junction_hsa04540 4 88 0.3278 0.4371
40 Notch_signaling_pathway_hsa04330 2 48 0.4709 0.6122
41 Calcium_signaling_pathway_hsa04020 6 182 0.5542 0.6957
42 Phagosome_hsa04145 5 152 0.5619 0.6957
43 Necroptosis_hsa04217 5 164 0.6293 0.761
44 Peroxisome_hsa04146 2 83 0.7619 0.8794
45 NF_kappa_B_signaling_pathway_hsa04064 2 95 0.8237 0.9113
46 Neuroactive_ligand_receptor_interaction_hsa04080 6 278 0.8976 0.9725
47 Cell_adhesion_molecules_.CAMs._hsa04514 2 145 0.9538 0.9956
48 Cytokine_cytokine_receptor_interaction_hsa04060 4 270 0.9789 0.9956

Quest ID: c59ea163dc6303695a76cd6fd2995e6c