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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-106b-3p ERGIC1 -1.02 0.00426 0.69 0.70545 miRNAWalker2 validate -0.12 0.01045
2 hsa-miR-106b-3p KIAA0232 -1.02 0.00426 0.91 0.62378 miRNAWalker2 validate -0.11 0.02715
3 hsa-miR-106b-3p MTMR3 -1.02 0.00426 0.19 0.92739 miRNAWalker2 validate -0.1 0.03283
4 hsa-miR-106b-3p PRDM2 -1.02 0.00426 0.14 0.93526 miRNAWalker2 validate -0.09 0.04098
5 hsa-miR-106b-3p SH3BP4 -1.02 0.00426 1.12 0.53932 miRNAWalker2 validate -0.27 0.00402
6 hsa-miR-106b-3p UQCR11 -1.02 0.00426 0.4 0.86485 miRNAWalker2 validate -0.09 0.009
7 hsa-miR-149-5p AGO1 3.12 0.01101 -0.27 0.874 miRNAWalker2 validate -0.06 0.0004
8 hsa-miR-149-5p ALYREF 3.12 0.01101 -0.85 0.697 miRNAWalker2 validate -0.09 0.03688
9 hsa-miR-149-5p ARPC2 3.12 0.01101 -0.46 0.87458 miRNAWalker2 validate -0.07 0.00504
10 hsa-miR-149-5p ARRB2 3.12 0.01101 -0.52 0.80444 miRNAWalker2 validate -0.08 0.01559
11 hsa-miR-149-5p ATAD3A 3.12 0.01101 -1.1 0.5997 miRNAWalker2 validate -0.19 0
12 hsa-miR-149-5p BID 3.12 0.01101 -0.72 0.72083 miRNAWalker2 validate -0.14 1.0E-5
13 hsa-miR-149-5p BIRC5 3.12 0.01101 -1.75 0.47362 miRNAWalker2 validate -0.17 0.02877
14 hsa-miR-149-5p CALD1 3.12 0.01101 -0.32 0.86115 miRNAWalker2 validate -0.07 0.00744
15 hsa-miR-149-5p CALR 3.12 0.01101 -0.64 0.76691 miRNAWalker2 validate -0.12 0
16 hsa-miR-149-5p CBS 3.12 0.01101 -2.31 0.24372 miRNAWalker2 validate -0.34 0.00023
17 hsa-miR-149-5p CCT4 3.12 0.01101 -0.42 0.84686 miRNAWalker2 validate -0.07 0.00011
18 hsa-miR-149-5p CCT6A 3.12 0.01101 -0.51 0.83643 miRNAWalker2 validate -0.08 0.00684
19 hsa-miR-149-5p CDK5RAP2 3.12 0.01101 -0.11 0.9552 miRNAWalker2 validate -0.06 0.04039
20 hsa-miR-149-5p CSTF2 3.12 0.01101 -0.21 0.917 miRNAWalker2 validate -0.07 0.00593
21 hsa-miR-149-5p DCUN1D5 3.12 0.01101 -0.48 0.84297 miRNAWalker2 validate -0.14 7.0E-5
22 hsa-miR-149-5p DDT 3.12 0.01101 -0.31 0.90377 miRNAWalker2 validate -0.1 0.00223
23 hsa-miR-149-5p DESI1 3.12 0.01101 -0.26 0.86664 miRNAWalker2 validate -0.05 0.01396
24 hsa-miR-149-5p DGCR14 3.12 0.01101 -0.2 0.91191 miRNAWalker2 validate -0.06 0.00259
25 hsa-miR-149-5p E2F3 3.12 0.01101 -1.39 0.53069 miRNAWalker2 validate -0.26 0
26 hsa-miR-149-5p ETS2 3.12 0.01101 -0.53 0.76747 miRNAWalker2 validate -0.13 0
27 hsa-miR-149-5p FOXM1 3.12 0.01101 -2.01 0.25686 miRNAWalker2 validate; MirTarget -0.19 0.0054 25613903; 25613903; 25613903; 25613903 MicroRNA-149 suppresses colorectal cancer cell migration and invasion by directly targeting forkhead box transcription factor FOXM1;The study further explored whether miR-149 inhibits migration and invasion of CRC cells by targeting the mammalian Forkhead Box M1 FOXM1 miR-149 was significantly downregulated in CRC tissues and low miR-149 expression was observed to be significantly correlated with lymph node or distant metastasis and advanced TNM stage of CRC patients;Gain- and loss - of - function assays indicated that miR-149 significantly inhibited growth migration and invasion of CRC cells by targeting FOXM1;Furthermore FOXM1 was significantly uiregulated in CRC tissues and inversely correlated with miR-149 expression
28 hsa-miR-149-5p FZD5 3.12 0.01101 -0.39 0.8106 miRNAWalker2 validate; miRNATAP -0.08 0.00898
29 hsa-miR-149-5p GAPDH 3.12 0.01101 -1.02 0.72664 miRNAWalker2 validate -0.12 0.00533
30 hsa-miR-149-5p GFPT2 3.12 0.01101 -0.57 0.76823 miRNAWalker2 validate -0.1 0.04492
31 hsa-miR-149-5p GPI 3.12 0.01101 -0.76 0.78548 miRNAWalker2 validate -0.14 0.0003
32 hsa-miR-149-5p HDAC2 3.12 0.01101 -0.85 0.7371 miRNAWalker2 validate -0.15 0.00021
33 hsa-miR-149-5p HUWE1 3.12 0.01101 -0.15 0.92966 miRNAWalker2 validate -0.05 0.0384
34 hsa-miR-149-5p IFI30 3.12 0.01101 -1.05 0.7115 miRNAWalker2 validate -0.15 0.00327
35 hsa-miR-149-5p ILF2 3.12 0.01101 -0.79 0.77486 miRNAWalker2 validate -0.12 0.00071
36 hsa-miR-149-5p ILF3 3.12 0.01101 -0.35 0.87155 miRNAWalker2 validate -0.06 0.00979
37 hsa-miR-149-5p KHSRP 3.12 0.01101 -0.48 0.80954 miRNAWalker2 validate -0.11 0
38 hsa-miR-149-5p KIF1A 3.12 0.01101 -0.72 0.61239 miRNAWalker2 validate -0.08 0.00804
39 hsa-miR-149-5p KIF1C 3.12 0.01101 -0.2 0.93859 miRNAWalker2 validate -0.06 0.04994
40 hsa-miR-149-5p KLHDC3 3.12 0.01101 -0.82 0.65391 miRNAWalker2 validate -0.1 0.00063
41 hsa-miR-149-5p LGI2 3.12 0.01101 -0.36 0.8085 miRNAWalker2 validate -0.07 0.03394
42 hsa-miR-149-5p LRRC42 3.12 0.01101 -0.5 0.80034 miRNAWalker2 validate -0.07 0.02077
43 hsa-miR-149-5p LRRC8A 3.12 0.01101 -0.19 0.92453 miRNAWalker2 validate -0.06 0.0213
44 hsa-miR-149-5p MID1 3.12 0.01101 -1.02 0.50335 miRNAWalker2 validate -0.18 0
45 hsa-miR-149-5p MRPS25 3.12 0.01101 -0.76 0.76197 miRNAWalker2 validate -0.15 9.0E-5
46 hsa-miR-149-5p MYH9 3.12 0.01101 -0.36 0.876 miRNAWalker2 validate; miRNATAP -0.09 0.03062
47 hsa-miR-149-5p NAT10 3.12 0.01101 -0.55 0.79117 miRNAWalker2 validate -0.07 0.0371
48 hsa-miR-149-5p NECAP2 3.12 0.01101 -0.55 0.78305 miRNAWalker2 validate -0.06 0.01401
49 hsa-miR-149-5p NOC2L 3.12 0.01101 -0.28 0.87992 miRNAWalker2 validate -0.06 0.01517
50 hsa-miR-149-5p NONO 3.12 0.01101 -0.17 0.94156 miRNAWalker2 validate; miRNATAP -0.08 0.00149
51 hsa-miR-149-5p PABPC1 3.12 0.01101 -0.57 0.84703 miRNAWalker2 validate -0.08 0.01905
52 hsa-miR-149-5p PLEKHO1 3.12 0.01101 -0.72 0.78249 miRNAWalker2 validate -0.11 0.00364
53 hsa-miR-149-5p PLOD1 3.12 0.01101 -1.31 0.54879 miRNAWalker2 validate -0.22 0
54 hsa-miR-149-5p PLSCR3 3.12 0.01101 -0.24 0.92576 miRNAWalker2 validate -0.06 0.03718
55 hsa-miR-149-5p POLR3D 3.12 0.01101 -0.76 0.68386 miRNAWalker2 validate -0.12 0.00017
56 hsa-miR-149-5p PSMD8 3.12 0.01101 -0.37 0.85839 miRNAWalker2 validate -0.06 0.00436
57 hsa-miR-149-5p PTPRK 3.12 0.01101 -1 0.68703 miRNAWalker2 validate; miRNATAP -0.19 0.00123
58 hsa-miR-149-5p RFC2 3.12 0.01101 -0.64 0.7343 miRNAWalker2 validate -0.06 0.04158
59 hsa-miR-149-5p RPL18A 3.12 0.01101 -0.55 0.85221 miRNAWalker2 validate -0.1 0.00213
60 hsa-miR-149-5p RRP1 3.12 0.01101 -1 0.62052 miRNAWalker2 validate -0.13 4.0E-5
61 hsa-miR-149-5p SBF1 3.12 0.01101 -0.53 0.77898 miRNAWalker2 validate -0.09 0.00351
62 hsa-miR-149-5p SDC1 3.12 0.01101 -0.58 0.79473 miRNAWalker2 validate -0.13 0.01316 25462564; 25462564; 25462564; 25462564 In this study we examined the expression of miRNA-126 miR-126 and miR-149 in prostate cancer and investigated the molecular mechanisms by which they affect syndecan-1 in prostate cancer;After silencing syndecan-1 miR-126 and/or miR-149 in the PC3 cells cell proliferation senescence and p21 induction were assessed using the MTS assay senescence-associated β-galactosidase SA-β-Gal assay and immunocytochemistry respectively;When syndecan-1 was silenced the PC3 cells showed reduced expression of miR-126 and miR-149 most effectively;Our results suggest that miR-126 and miR-149 are associated with the expression of syndecan-1 in prostate cancer cells
63 hsa-miR-149-5p SKI 3.12 0.01101 -0.21 0.89675 miRNAWalker2 validate -0.06 0.0178
64 hsa-miR-149-5p SLC2A1 3.12 0.01101 -1.17 0.59376 miRNAWalker2 validate -0.14 0.01618
65 hsa-miR-149-5p SMCHD1 3.12 0.01101 -0.44 0.79105 miRNAWalker2 validate -0.06 0.00089
66 hsa-miR-149-5p STAG1 3.12 0.01101 -0.38 0.8033 miRNAWalker2 validate -0.07 0.0045
67 hsa-miR-149-5p SUPT5H 3.12 0.01101 -0.51 0.81165 miRNAWalker2 validate -0.09 0.00033
68 hsa-miR-149-5p TCF20 3.12 0.01101 -0.46 0.81731 miRNAWalker2 validate -0.11 0.00173
69 hsa-miR-149-5p TKT 3.12 0.01101 -0.77 0.76912 miRNAWalker2 validate -0.18 0
70 hsa-miR-149-5p TRIP6 3.12 0.01101 -1.13 0.63776 miRNAWalker2 validate -0.18 0.00149
71 hsa-miR-149-5p TTL 3.12 0.01101 -0.34 0.81147 miRNAWalker2 validate -0.05 5.0E-5
72 hsa-miR-149-5p YARS2 3.12 0.01101 -0.36 0.85396 miRNAWalker2 validate -0.07 0.00071
73 hsa-miR-149-5p YBX1 3.12 0.01101 -1.79 0.45477 miRNAWalker2 validate -0.28 0
74 hsa-miR-149-5p YTHDF1 3.12 0.01101 -0.13 0.9531 miRNAWalker2 validate -0.06 0.02397
75 hsa-miR-149-5p ZNF276 3.12 0.01101 -0.36 0.84885 miRNAWalker2 validate -0.08 0.00115
76 hsa-miR-26b-5p LY6D 1.08 0.63865 -3.07 0.04745 miRNAWalker2 validate -0.6 0.00053
77 hsa-miR-26b-5p PSAT1 1.08 0.63865 -3.67 0.0491 miRNAWalker2 validate -0.76 8.0E-5
78 hsa-miR-29b-2-5p ZC3H18 1.52 4.0E-5 -0.77 0.66808 miRNAWalker2 validate -0.12 0.04288
79 hsa-miR-335-5p ART3 1.07 0.43467 -3.13 0.02758 miRNAWalker2 validate -0.29 0.01873
80 hsa-miR-33b-5p ABCA1 0.86 0.01091 -0.19 0.90294 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.07 0.00466
81 hsa-miR-342-3p PSAT1 1.94 0.35273 -3.67 0.0491 miRNAWalker2 validate -0.91 0
82 hsa-miR-375 FOLR1 3.32 0.05354 -3.7 0.04664 miRNAWalker2 validate -0.31 0.00039
83 hsa-miR-449a CDK6 3.28 0.00386 -1.38 0.41289 miRNAWalker2 validate; miRTarBase; miRNATAP -0.08 0.00114
84 hsa-miR-449a HDAC1 3.28 0.00386 -0.15 0.95136 miRNAWalker2 validate; miRTarBase; miRanda; miRNATAP -0.05 0.00607
85 hsa-miR-449a MET 3.28 0.00386 -0.96 0.53603 miRNAWalker2 validate; miRTarBase; PITA; miRanda -0.06 0.00126
86 hsa-miR-519a-3p DICER1 -2.74 0 0.4 0.81404 miRNAWalker2 validate; miRTarBase; mirMAP -0.07 0.01605
87 hsa-miR-9-5p ACADSB -3.36 1.0E-5 2.24 0.20859 miRNAWalker2 validate -0.32 0
88 hsa-miR-9-5p APBB2 -3.36 1.0E-5 1.71 0.40498 miRNAWalker2 validate -0.26 0
89 hsa-miR-9-5p AUH -3.36 1.0E-5 0.44 0.82384 miRNAWalker2 validate; miRNATAP -0.08 0.0051
90 hsa-miR-9-5p BIK -3.36 1.0E-5 1.65 0.43724 miRNAWalker2 validate -0.19 0.00125
91 hsa-miR-9-5p BOD1L1 -3.36 1.0E-5 0.46 0.77608 miRNAWalker2 validate -0.05 0.01144
92 hsa-miR-9-5p CCND1 -3.36 1.0E-5 1.75 0.38407 miRNAWalker2 validate -0.26 0.00015
93 hsa-miR-9-5p CCNDBP1 -3.36 1.0E-5 0.59 0.80812 miRNAWalker2 validate; MirTarget -0.15 0.00024
94 hsa-miR-9-5p CCNG1 -3.36 1.0E-5 0.32 0.86825 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.1 0.00257
95 hsa-miR-9-5p CERS2 -3.36 1.0E-5 0.99 0.69052 miRNAWalker2 validate -0.13 0.00229
96 hsa-miR-9-5p CERS4 -3.36 1.0E-5 1.7 0.40661 miRNAWalker2 validate -0.26 0
97 hsa-miR-9-5p COL12A1 -3.36 1.0E-5 1.31 0.54066 miRNAWalker2 validate; miRNATAP -0.19 0.0031
98 hsa-miR-9-5p COLEC12 -3.36 1.0E-5 0.97 0.60644 miRNAWalker2 validate -0.21 0.00032
99 hsa-miR-9-5p CXXC5 -3.36 1.0E-5 1.93 0.41517 miRNAWalker2 validate -0.31 0
100 hsa-miR-9-5p DMXL1 -3.36 1.0E-5 0.33 0.83576 miRNAWalker2 validate -0.06 3.0E-5
101 hsa-miR-9-5p FLNB -3.36 1.0E-5 0.93 0.61409 miRNAWalker2 validate -0.1 0.03825
102 hsa-miR-9-5p FSTL3 -3.36 1.0E-5 0.87 0.61901 miRNAWalker2 validate -0.13 0.00036
103 hsa-miR-9-5p HN1L -3.36 1.0E-5 0.82 0.67924 miRNAWalker2 validate; MirTarget -0.07 0.02072
104 hsa-miR-9-5p MCC -3.36 1.0E-5 0.59 0.70325 miRNAWalker2 validate; MirTarget -0.12 0.00066
105 hsa-miR-9-5p NBEA -3.36 1.0E-5 1.36 0.44369 miRNAWalker2 validate -0.23 0
106 hsa-miR-9-5p NRIP3 -3.36 1.0E-5 0.91 0.5323 miRNAWalker2 validate -0.16 0.00374
107 hsa-miR-9-5p PDZK1 -3.36 1.0E-5 2 0.23291 miRNAWalker2 validate -0.27 0.01588
108 hsa-miR-9-5p PIGB -3.36 1.0E-5 0.47 0.79037 miRNAWalker2 validate -0.12 0
109 hsa-miR-9-5p PQLC3 -3.36 1.0E-5 0.35 0.86246 miRNAWalker2 validate -0.11 0.00192
110 hsa-miR-9-5p RASSF8 -3.36 1.0E-5 0.26 0.85724 miRNAWalker2 validate -0.05 0.02943
111 hsa-miR-9-5p SLC22A5 -3.36 1.0E-5 1.7 0.41158 miRNAWalker2 validate -0.21 0.00019
112 hsa-miR-9-5p SLC35E2 -3.36 1.0E-5 0.57 0.72641 miRNAWalker2 validate -0.09 0.0001
113 hsa-miR-9-5p SYPL1 -3.36 1.0E-5 0.06 0.97603 miRNAWalker2 validate -0.08 0.0233
114 hsa-miR-9-5p TBC1D9 -3.36 1.0E-5 3.79 0.09601 miRNAWalker2 validate -0.55 0
115 hsa-miR-9-5p TESK2 -3.36 1.0E-5 0.43 0.79616 miRNAWalker2 validate; MirTarget -0.11 0.00192
116 hsa-miR-9-5p UGDH -3.36 1.0E-5 1.28 0.50259 miRNAWalker2 validate -0.21 1.0E-5
117 hsa-miR-9-5p AP3B1 -3.36 1.0E-5 0.32 0.88621 miRTarBase -0.07 0.00384
118 hsa-miR-10a-3p APCDD1L 1.42 0.03159 -1.1 0.44769 MirTarget; miRNATAP -0.1 0.0358
119 hsa-miR-135a-5p MMP11 1.16 0.04954 1.45 0.57829 MirTarget -0.19 0.04628
120 hsa-miR-135a-5p MXRA5 1.16 0.04954 0.49 0.81283 MirTarget -0.14 0.01756
121 hsa-miR-135a-5p SPSB1 1.16 0.04954 -0.61 0.7487 MirTarget -0.1 0.00586
122 hsa-miR-135a-5p ACTR3B 1.16 0.04954 -1.01 0.575 MirTarget -0.09 0.01113
123 hsa-miR-135a-5p NET1 1.16 0.04954 0.13 0.95885 MirTarget; miRNATAP -0.12 0.01563
124 hsa-miR-135a-5p ANGPTL2 1.16 0.04954 0.27 0.89589 MirTarget; miRNATAP -0.1 0.0187
125 hsa-miR-135a-5p NAP1L2 1.16 0.04954 0.06 0.9685 MirTarget -0.07 0.04451
126 hsa-miR-135a-5p PRKD3 1.16 0.04954 -0.85 0.59962 MirTarget; miRNATAP -0.07 0.00131
127 hsa-miR-135a-5p ANKRD33B 1.16 0.04954 -0.23 0.87543 MirTarget -0.06 0.04951
128 hsa-miR-135a-5p VASH2 1.16 0.04954 -0.78 0.64495 MirTarget -0.15 0.0035
129 hsa-miR-135a-5p PDP1 1.16 0.04954 0.2 0.90854 MirTarget -0.1 0.02374
130 hsa-miR-135a-5p CDR2L 1.16 0.04954 -0.26 0.90304 MirTarget -0.09 0.02769
131 hsa-miR-135a-5p TMEM97 1.16 0.04954 0.08 0.96335 MirTarget; miRNATAP -0.11 0.02473
132 hsa-miR-135a-5p STMN1 1.16 0.04954 -0.8 0.69766 MirTarget -0.06 0.03766
133 hsa-miR-135a-5p PATL1 1.16 0.04954 -0.53 0.75764 MirTarget; miRNATAP -0.06 0.01169
134 hsa-miR-135a-5p TCF19 1.16 0.04954 -0.76 0.60532 MirTarget -0.05 0.04908
135 hsa-miR-135a-5p FOXN2 1.16 0.04954 -0.74 0.6739 MirTarget; miRNATAP -0.14 0.00152
136 hsa-miR-135a-5p CREG1 1.16 0.04954 -0.86 0.71445 MirTarget; miRNATAP -0.08 0.04172
137 hsa-miR-135a-5p RASAL2 1.16 0.04954 -0.58 0.73449 MirTarget -0.09 0.00053
138 hsa-miR-135a-5p KIAA1549L 1.16 0.04954 -1.39 0.4114 MirTarget -0.17 0.00546
139 hsa-miR-135a-5p SSR2 1.16 0.04954 -0.1 0.96778 MirTarget -0.07 0.0008
140 hsa-miR-135a-5p MEGF6 1.16 0.04954 0.28 0.88433 MirTarget -0.08 0.04783
141 hsa-miR-135a-5p TLDC1 1.16 0.04954 -1.29 0.50131 MirTarget -0.13 0.00251
142 hsa-miR-135a-5p FOXN3 1.16 0.04954 -0.35 0.87262 MirTarget; miRNATAP -0.07 0.02285
143 hsa-miR-135b-5p MMP11 -4.4 0.00013 1.45 0.57829 MirTarget -0.16 0.02244
144 hsa-miR-135b-5p NBEA -4.4 0.00013 1.36 0.44369 MirTarget -0.12 0.00066
145 hsa-miR-135b-5p TMEM9 -4.4 0.00013 0.59 0.79731 MirTarget -0.06 0.04842
146 hsa-miR-135b-5p SLC24A2 -4.4 0.00013 0.65 0.65684 MirTarget -0.06 0.00408
147 hsa-miR-135b-5p SC5D -4.4 0.00013 0.43 0.8288 MirTarget -0.08 0.03405
148 hsa-miR-135b-5p SETD7 -4.4 0.00013 0.25 0.87589 MirTarget; mirMAP -0.05 8.0E-5
149 hsa-miR-135b-5p MYO6 -4.4 0.00013 1.23 0.60133 MirTarget -0.11 0.00129
150 hsa-miR-135b-5p PSD3 -4.4 0.00013 1.86 0.28381 MirTarget; mirMAP -0.19 0.00132
NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF CELL DIFFERENTIATION 224 1492 4.525e-19 2.105e-15
2 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 197 1275 3.694e-18 8.595e-15
3 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 237 1672 4.781e-17 7.415e-14
4 REGULATION OF CELL DEVELOPMENT 138 836 3.208e-15 3.732e-12
5 LOCOMOTION 169 1114 6.496e-15 6.045e-12
6 POSITIVE REGULATION OF GENE EXPRESSION 232 1733 7.116e-14 4.426e-11
7 CELL MOTILITY 134 835 7.609e-14 4.426e-11
8 LOCALIZATION OF CELL 134 835 7.609e-14 4.426e-11
9 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 239 1805 9.39e-14 4.855e-11
10 REGULATION OF CELLULAR COMPONENT MOVEMENT 126 771 1.167e-13 5.428e-11
11 INTRACELLULAR SIGNAL TRANSDUCTION 213 1572 2.677e-13 1.132e-10
12 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 167 1152 5.34e-13 2.07e-10
13 REGULATION OF NEURON DIFFERENTIATION 98 554 6.183e-13 2.213e-10
14 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 165 1142 9.898e-13 3.29e-10
15 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 120 750 2.021e-12 6.27e-10
16 CELL DEVELOPMENT 194 1426 2.498e-12 7.264e-10
17 POSITIVE REGULATION OF CELL DIFFERENTIATION 128 823 2.762e-12 7.56e-10
18 RESPONSE TO ENDOGENOUS STIMULUS 193 1450 2.048e-11 5.295e-09
19 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 214 1656 2.391e-11 5.855e-09
20 REGULATION OF CELL PROLIFERATION 196 1496 5.685e-11 1.323e-08
21 TISSUE DEVELOPMENT 198 1518 6.621e-11 1.467e-08
22 REGULATION OF NEURON PROJECTION DEVELOPMENT 74 408 1.347e-10 2.849e-08
23 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 113 740 1.741e-10 3.523e-08
24 NEUROGENESIS 184 1402 2.065e-10 4.003e-08
25 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 182 1395 4.231e-10 7.875e-08
26 CARDIOVASCULAR SYSTEM DEVELOPMENT 117 788 4.713e-10 8.122e-08
27 CIRCULATORY SYSTEM DEVELOPMENT 117 788 4.713e-10 8.122e-08
28 IMMUNE SYSTEM PROCESS 241 1984 5.329e-10 8.265e-08
29 PROTEIN PHOSPHORYLATION 134 944 5.213e-10 8.265e-08
30 VASCULATURE DEVELOPMENT 80 469 5.191e-10 8.265e-08
31 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 221 1784 5.585e-10 8.383e-08
32 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 140 1004 7.08e-10 9.983e-08
33 POSITIVE REGULATION OF CELL DEVELOPMENT 80 472 7.076e-10 9.983e-08
34 POSITIVE REGULATION OF MOLECULAR FUNCTION 221 1791 7.937e-10 1.086e-07
35 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 193 1517 9.606e-10 1.277e-07
36 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 39 162 1.043e-09 1.349e-07
37 CELLULAR COMPONENT MORPHOGENESIS 128 900 1.151e-09 1.447e-07
38 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 141 1021 1.182e-09 1.447e-07
39 NEGATIVE REGULATION OF GENE EXPRESSION 190 1493 1.29e-09 1.539e-07
40 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 139 1008 1.722e-09 2.003e-07
41 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 78 465 1.883e-09 2.137e-07
42 REGULATION OF CELL ADHESION 97 629 2.107e-09 2.334e-07
43 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 62 337 2.385e-09 2.581e-07
44 REGULATION OF TRANSPORT 220 1804 2.456e-09 2.597e-07
45 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 175 1360 2.735e-09 2.828e-07
46 POSITIVE REGULATION OF RESPONSE TO STIMULUS 232 1929 2.929e-09 2.939e-07
47 RESPONSE TO OXYGEN CONTAINING COMPOUND 177 1381 2.969e-09 2.939e-07
48 ORGAN MORPHOGENESIS 120 841 3.213e-09 3.115e-07
49 BLOOD VESSEL MORPHOGENESIS 65 364 3.418e-09 3.246e-07
50 REGULATION OF CELL PROJECTION ORGANIZATION 88 558 3.992e-09 3.649e-07
51 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 81 498 4e-09 3.649e-07
52 REGULATION OF CELL MORPHOGENESIS 87 552 5.047e-09 4.517e-07
53 REGULATION OF ACTIN FILAMENT BASED PROCESS 58 312 5.244e-09 4.604e-07
54 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 187 1492 5.833e-09 5.026e-07
55 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 235 1977 6.488e-09 5.489e-07
56 RESPONSE TO ORGANIC CYCLIC COMPOUND 127 917 6.952e-09 5.777e-07
57 PHOSPHORYLATION 159 1228 1.018e-08 8.311e-07
58 VESICLE MEDIATED TRANSPORT 160 1239 1.095e-08 8.781e-07
59 POSITIVE REGULATION OF CATALYTIC ACTIVITY 188 1518 1.32e-08 1.041e-06
60 REGULATION OF PROTEIN MODIFICATION PROCESS 207 1710 1.425e-08 1.105e-06
61 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 101 689 1.481e-08 1.13e-06
62 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 113 799 1.546e-08 1.161e-06
63 REGULATION OF CELL SUBSTRATE ADHESION 38 173 2.517e-08 1.859e-06
64 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 219 1848 2.978e-08 2.143e-06
65 CELL PROJECTION ORGANIZATION 123 902 2.994e-08 2.143e-06
66 REGULATION OF HYDROLASE ACTIVITY 167 1327 3.13e-08 2.207e-06
67 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 128 957 4.844e-08 3.364e-06
68 RESPONSE TO EXTERNAL STIMULUS 215 1821 5.463e-08 3.738e-06
69 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 111 801 6.226e-08 4.198e-06
70 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 79 513 7.094e-08 4.715e-06
71 POSITIVE REGULATION OF LOCOMOTION 68 420 8.47e-08 5.551e-06
72 NEGATIVE REGULATION OF CELL DEATH 118 872 8.803e-08 5.689e-06
73 SKELETAL SYSTEM DEVELOPMENT 72 455 9.065e-08 5.778e-06
74 REGULATION OF CELL DEATH 179 1472 1.115e-07 7.01e-06
75 POSITIVE REGULATION OF HYDROLASE ACTIVITY 121 905 1.168e-07 7.247e-06
76 UROGENITAL SYSTEM DEVELOPMENT 53 299 1.209e-07 7.403e-06
77 REGULATION OF GTPASE ACTIVITY 96 673 1.276e-07 7.708e-06
78 GROWTH 66 410 1.629e-07 9.717e-06
79 CELL GROWTH 31 135 1.659e-07 9.772e-06
80 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 69 437 1.825e-07 1.062e-05
81 POSITIVE REGULATION OF NEURON DIFFERENTIATION 53 306 2.602e-07 1.495e-05
82 ACTIN FILAMENT BASED PROCESS 70 450 2.665e-07 1.512e-05
83 TUBE MORPHOGENESIS 55 323 2.761e-07 1.548e-05
84 CENTRAL NERVOUS SYSTEM DEVELOPMENT 116 872 2.804e-07 1.553e-05
85 TELENCEPHALON DEVELOPMENT 43 228 3.226e-07 1.766e-05
86 REGULATION OF PHOSPHORUS METABOLIC PROCESS 191 1618 3.376e-07 1.826e-05
87 NEURON PROJECTION MORPHOGENESIS 64 402 3.745e-07 2.003e-05
88 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 38 191 3.827e-07 2.024e-05
89 TAXIS 71 464 4.153e-07 2.171e-05
90 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 49 278 4.264e-07 2.205e-05
91 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 47 262 4.313e-07 2.205e-05
92 NEGATIVE REGULATION OF CELL DEVELOPMENT 52 303 4.516e-07 2.284e-05
93 REGULATION OF CYTOSKELETON ORGANIZATION 75 502 5.134e-07 2.569e-05
94 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 43 232 5.296e-07 2.621e-05
95 PROTEIN LOCALIZATION 208 1805 5.653e-07 2.769e-05
96 RESPONSE TO ESTROGEN 41 218 6.49e-07 3.113e-05
97 CELLULAR RESPONSE TO NITROGEN COMPOUND 75 505 6.49e-07 3.113e-05
98 RESPONSE TO LIPID 116 888 7.135e-07 3.388e-05
99 NEGATIVE REGULATION OF CELL COMMUNICATION 147 1192 7.43e-07 3.492e-05
100 LEUKOCYTE DIFFERENTIATION 50 292 7.998e-07 3.721e-05
101 REGULATION OF KINASE ACTIVITY 104 776 8.273e-07 3.776e-05
102 POSITIVE REGULATION OF CELL PROLIFERATION 108 814 8.277e-07 3.776e-05
103 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 141 1135 8.395e-07 3.792e-05
104 NEGATIVE REGULATION OF CELL DIFFERENTIATION 86 609 8.87e-07 3.968e-05
105 IMMUNE SYSTEM DEVELOPMENT 83 582 9.185e-07 4.07e-05
106 REGULATION OF CATABOLIC PROCESS 99 731 9.482e-07 4.162e-05
107 CHEMICAL HOMEOSTASIS 114 874 9.606e-07 4.177e-05
108 CELLULAR RESPONSE TO LIPID 69 457 9.902e-07 4.189e-05
109 PALLIUM DEVELOPMENT 32 153 9.903e-07 4.189e-05
110 REGULATION OF ORGANELLE ORGANIZATION 145 1178 9.889e-07 4.189e-05
111 POSITIVE REGULATION OF CELL COMMUNICATION 180 1532 1.038e-06 4.235e-05
112 RESPONSE TO GROWTH FACTOR 71 475 1.01e-06 4.235e-05
113 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 25 104 1.03e-06 4.235e-05
114 REGULATION OF AXONOGENESIS 34 168 1.024e-06 4.235e-05
115 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 51 303 1.059e-06 4.287e-05
116 BIOLOGICAL ADHESION 130 1032 1.102e-06 4.42e-05
117 CELL PART MORPHOGENESIS 88 633 1.291e-06 5.091e-05
118 RESPONSE TO AMINO ACID 26 112 1.289e-06 5.091e-05
119 ESTABLISHMENT OF LOCALIZATION IN CELL 193 1676 1.595e-06 6.236e-05
120 NEURON PROJECTION DEVELOPMENT 78 545 1.698e-06 6.583e-05
121 EPITHELIUM DEVELOPMENT 120 945 1.942e-06 7.469e-05
122 ANGIOGENESIS 49 293 2.068e-06 7.889e-05
123 RESPONSE TO NITROGEN COMPOUND 111 859 2.096e-06 7.928e-05
124 POSITIVE REGULATION OF AXONOGENESIS 19 69 2.303e-06 8.64e-05
125 REGULATION OF CELLULAR LOCALIZATION 153 1277 2.383e-06 8.87e-05
126 HEAD DEVELOPMENT 95 709 2.503e-06 9.243e-05
127 SECOND MESSENGER MEDIATED SIGNALING 32 160 2.75e-06 0.0001007
128 TUBE DEVELOPMENT 78 552 2.777e-06 0.0001009
129 REGULATION OF POTASSIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 14 41 3.045e-06 0.0001098
130 RESPONSE TO WOUNDING 79 563 3.142e-06 0.0001116
131 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 112 876 3.122e-06 0.0001116
132 REGULATION OF CELL MATRIX ADHESION 22 90 3.348e-06 0.000118
133 REGULATION OF TRANSFERASE ACTIVITY 119 946 3.407e-06 0.0001192
134 POSITIVE REGULATION OF CELL ADHESION 58 376 3.617e-06 0.0001256
135 DEVELOPMENTAL GROWTH 53 333 3.71e-06 0.0001279
136 DENDRITE MORPHOGENESIS 14 42 4.218e-06 0.0001443
137 RESPONSE TO DRUG 64 431 4.255e-06 0.0001445
138 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 55 352 4.332e-06 0.0001461
139 ESTABLISHMENT OR MAINTENANCE OF CELL POLARITY 29 141 4.454e-06 0.0001491
140 REGULATION OF CELLULAR COMPONENT BIOGENESIS 100 767 4.584e-06 0.0001513
141 RESPONSE TO HORMONE 113 893 4.586e-06 0.0001513
142 ORGANELLE LOCALIZATION 62 415 4.906e-06 0.0001608
143 REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 55 354 5.149e-06 0.0001675
144 DENDRITE DEVELOPMENT 20 79 5.202e-06 0.0001681
145 RESPONSE TO ABIOTIC STIMULUS 126 1024 5.315e-06 0.0001706
146 MORPHOGENESIS OF AN EPITHELIUM 60 400 6.106e-06 0.0001946
147 AMINOGLYCAN METABOLIC PROCESS 32 166 6.211e-06 0.0001966
148 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 15 49 6.375e-06 0.0002001
149 ENDOCYTOSIS 72 509 6.408e-06 0.0002001
150 NEURON DEVELOPMENT 91 687 6.512e-06 0.0002009
151 REGULATION OF CELL CYCLE 118 949 6.521e-06 0.0002009
152 FOREBRAIN DEVELOPMENT 55 357 6.646e-06 0.0002035
153 REGULATION OF TRANSPORTER ACTIVITY 36 198 6.81e-06 0.0002071
154 NEURON DIFFERENTIATION 110 874 7.844e-06 0.000237
155 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 56 368 8.002e-06 0.0002402
156 REGULATION OF STEM CELL PROLIFERATION 21 88 8.328e-06 0.0002484
157 REGULATION OF AUTOPHAGY 42 249 8.697e-06 0.0002577
158 REGULATION OF MEMBRANE POTENTIAL 53 343 8.908e-06 0.0002623
159 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 126 1036 9.396e-06 0.0002699
160 CYTOSKELETON ORGANIZATION 106 838 9.224e-06 0.0002699
161 TISSUE MORPHOGENESIS 74 533 9.347e-06 0.0002699
162 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 126 1036 9.396e-06 0.0002699
163 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 60 406 9.762e-06 0.0002787
164 RESPONSE TO ALCOHOL 55 362 1.007e-05 0.0002857
165 LEUKOCYTE MIGRATION 43 259 1.028e-05 0.0002898
166 REGULATION OF VESICLE MEDIATED TRANSPORT 66 462 1.114e-05 0.0003124
167 REGULATION OF NEURON DEATH 42 252 1.176e-05 0.0003278
168 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 120 983 1.295e-05 0.0003588
169 DEVELOPMENTAL CELL GROWTH 19 77 1.326e-05 0.000365
170 POSITIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 11 30 1.616e-05 0.0004397
171 CELLULAR RESPONSE TO VASCULAR ENDOTHELIAL GROWTH FACTOR STIMULUS 11 30 1.616e-05 0.0004397
172 ANION HOMEOSTASIS 13 41 1.719e-05 0.0004624
173 MESENCHYME DEVELOPMENT 34 190 1.719e-05 0.0004624
174 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 15 53 1.839e-05 0.0004917
175 POSITIVE REGULATION OF ENDOCYTOSIS 24 114 1.922e-05 0.0005092
176 RESPONSE TO NUTRIENT 34 191 1.926e-05 0.0005092
177 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 28 144 1.952e-05 0.0005132
178 AMINOGLYCAN BIOSYNTHETIC PROCESS 23 107 1.997e-05 0.0005221
179 POSITIVE REGULATION OF AXON EXTENSION 12 36 2.048e-05 0.0005293
180 LAMELLIPODIUM ORGANIZATION 12 36 2.048e-05 0.0005293
181 CELLULAR RESPONSE TO OXIDATIVE STRESS 33 184 2.166e-05 0.0005568
182 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 16 60 2.223e-05 0.0005684
183 POSITIVE REGULATION OF TRANSPORT 114 936 2.363e-05 0.0006008
184 REGULATION OF EPITHELIAL CELL PROLIFERATION 45 285 2.392e-05 0.0006016
185 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORT 14 48 2.39e-05 0.0006016
186 RESPONSE TO ESTRADIOL 28 146 2.543e-05 0.0006361
187 CELL ACTIVATION 76 568 2.624e-05 0.000653
188 CELL CHEMOTAXIS 30 162 2.685e-05 0.0006646
189 HEART DEVELOPMENT 65 466 2.773e-05 0.0006814
190 POSITIVE REGULATION OF STEM CELL PROLIFERATION 16 61 2.783e-05 0.0006814
191 ESTABLISHMENT OF CELL POLARITY 20 88 2.916e-05 0.0007105
192 MUSCLE CELL DIFFERENTIATION 39 237 3.193e-05 0.0007738
193 PEPTIDYL SERINE MODIFICATION 28 148 3.291e-05 0.0007893
194 POSITIVE REGULATION OF CELL GROWTH 28 148 3.291e-05 0.0007893
195 BONE DEVELOPMENT 29 156 3.372e-05 0.0008005
196 MUSCLE STRUCTURE DEVELOPMENT 61 432 3.362e-05 0.0008005
197 RESPONSE TO STEROID HORMONE 68 497 3.406e-05 0.0008005
198 REGULATION OF DEVELOPMENTAL GROWTH 45 289 3.398e-05 0.0008005
199 LYMPHOCYTE ACTIVATION 51 342 3.466e-05 0.0008105
200 RHYTHMIC PROCESS 46 298 3.485e-05 0.0008109
201 CELL CYCLE PHASE TRANSITION 41 255 3.53e-05 0.0008157
202 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 76 573 3.541e-05 0.0008157
203 CENTRAL NERVOUS SYSTEM NEURON AXONOGENESIS 10 27 3.56e-05 0.0008161
204 CELLULAR RESPONSE TO EXTERNAL STIMULUS 42 264 3.678e-05 0.0008348
205 REGULATION OF METAL ION TRANSPORT 49 325 3.677e-05 0.0008348
206 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 12 38 3.786e-05 0.0008533
207 MYELOID CELL DIFFERENTIATION 33 189 3.796e-05 0.0008533
208 CALCIUM MEDIATED SIGNALING 20 90 4.116e-05 0.0009183
209 REGULATION OF ANATOMICAL STRUCTURE SIZE 65 472 4.125e-05 0.0009183
210 REGULATION OF MUSCLE ADAPTATION 16 63 4.285e-05 0.0009495
211 REGULATION OF EPITHELIAL CELL MIGRATION 30 166 4.333e-05 0.0009556
212 EMBRYONIC MORPHOGENESIS 72 539 4.478e-05 0.0009829
213 CEREBRAL CORTEX DEVELOPMENT 22 105 4.544e-05 0.0009926
214 REGULATION OF CELLULAR COMPONENT SIZE 50 337 4.706e-05 0.001023
215 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 87 684 4.744e-05 0.001027
216 RESPONSE TO OXYGEN LEVELS 47 311 4.948e-05 0.001066
217 REGULATION OF HOMEOSTATIC PROCESS 62 447 4.976e-05 0.001067
218 REGULATION OF NEURON APOPTOTIC PROCESS 33 192 5.246e-05 0.001115
219 PROTEIN AUTOPHOSPHORYLATION 33 192 5.246e-05 0.001115
220 POSTTRANSCRIPTIONAL REGULATION OF GENE EXPRESSION 62 448 5.316e-05 0.001119
221 REGULATION OF CARDIAC MUSCLE CONTRACTION BY CALCIUM ION SIGNALING 9 23 5.307e-05 0.001119
222 OSSIFICATION 40 251 5.359e-05 0.001123
223 EPHRIN RECEPTOR SIGNALING PATHWAY 19 85 5.836e-05 0.001212
224 HEART PROCESS 19 85 5.836e-05 0.001212
225 NEGATIVE REGULATION OF PHOSPHORYLATION 59 422 5.976e-05 0.001236
226 PLATELET DERIVED GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 11 34 6.194e-05 0.001273
227 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 105 867 6.209e-05 0.001273
228 CELL CYCLE 149 1316 6.27e-05 0.00128
229 CELLULAR MACROMOLECULE LOCALIZATION 141 1234 6.462e-05 0.001313
230 LEUKOCYTE ACTIVATION 58 414 6.491e-05 0.001313
231 EPITHELIAL CELL DEVELOPMENT 32 186 6.633e-05 0.00133
232 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 64 470 6.61e-05 0.00133
233 AMEBOIDAL TYPE CELL MIGRATION 28 154 6.878e-05 0.001374
234 MUCOPOLYSACCHARIDE METABOLIC PROCESS 22 108 7.112e-05 0.001408
235 NEGATIVE REGULATION OF CELL PROLIFERATION 82 643 7.098e-05 0.001408
236 REGULATION OF IMMUNE SYSTEM PROCESS 157 1403 7.179e-05 0.001415
237 NEGATIVE REGULATION OF LOCOMOTION 41 263 7.237e-05 0.001421
238 ION HOMEOSTASIS 75 576 7.32e-05 0.001431
239 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 37 229 7.48e-05 0.001456
240 REGULATION OF RESPONSE TO STRESS 163 1468 7.757e-05 0.001504
241 BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 9 24 7.864e-05 0.001506
242 POSITIVE REGULATION OF GROWTH 38 238 7.812e-05 0.001506
243 NEGATIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 9 24 7.864e-05 0.001506
244 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 79 616 7.935e-05 0.001513
245 CELLULAR RESPONSE TO AMINO ACID STIMULUS 14 53 8.017e-05 0.001523
246 REGULATION OF CELL SIZE 30 172 8.545e-05 0.001616
247 REGULATION OF RECEPTOR ACTIVITY 23 117 8.766e-05 0.001651
248 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 110 926 9.192e-05 0.001725
249 REGULATION OF WNT SIGNALING PATHWAY 46 310 9.256e-05 0.00173
250 RESPONSE TO ACID CHEMICAL 47 319 9.3e-05 0.001731
251 ESTABLISHMENT OF PROTEIN LOCALIZATION 158 1423 0.0001004 0.001859
252 STEM CELL DIFFERENTIATION 32 190 0.0001007 0.001859
253 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 21 103 0.0001016 0.001868
254 SINGLE ORGANISM BEHAVIOR 54 384 0.0001034 0.001894
255 ACTIN FILAMENT ORGANIZATION 30 174 0.0001061 0.001936
256 MESENCHYMAL CELL DIFFERENTIATION 25 134 0.0001075 0.001954
257 REGULATION OF POTASSIUM ION TRANSMEMBRANE TRANSPORT 15 61 0.0001099 0.001989
258 RESPONSE TO EXTRACELLULAR STIMULUS 60 441 0.0001129 0.002028
259 REGULATION OF GENERATION OF PRECURSOR METABOLITES AND ENERGY 19 89 0.0001127 0.002028
260 REGULATION OF GROWTH 80 633 0.0001169 0.00209
261 NEURAL CREST CELL DIFFERENTIATION 17 75 0.0001172 0.00209
262 CELLULAR RESPONSE TO ACID CHEMICAL 30 175 0.000118 0.002096
263 POSITIVE REGULATION OF CELL DEATH 77 605 0.0001245 0.002202
264 LYMPHOCYTE DIFFERENTIATION 34 209 0.0001253 0.002209
265 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 31 184 0.0001274 0.002238
266 FOREBRAIN CELL MIGRATION 15 62 0.0001339 0.002342
267 REGULATION OF POTASSIUM ION TRANSPORT 18 83 0.0001369 0.002385
268 CELLULAR RESPONSE TO GLUCOSE STARVATION 10 31 0.0001374 0.002385
269 POSITIVE REGULATION OF KINASE ACTIVITY 64 482 0.0001382 0.002391
270 REGULATION OF MUSCLE HYPERTROPHY 11 37 0.0001466 0.002516
271 CARDIAC MUSCLE CELL ACTION POTENTIAL 11 37 0.0001466 0.002516
272 CELL CYCLE PROCESS 124 1081 0.000152 0.0026
273 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 59 437 0.0001583 0.002697
274 POSITIVE REGULATION OF POTASSIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 7 16 0.0001615 0.002742
275 REGULATION OF SODIUM ION TRANSPORT 17 77 0.0001652 0.002785
276 AGING 40 264 0.0001647 0.002785
277 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 16 70 0.0001661 0.00279
278 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 20 99 0.0001678 0.002809
279 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 13 50 0.0001704 0.002842
280 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 25 138 0.0001746 0.002898
281 REGULATION OF ION TRANSPORT 75 592 0.000175 0.002898
282 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 71 554 0.0001828 0.003017
283 NEGATIVE REGULATION OF NEURON DEATH 29 171 0.0001843 0.00303
284 CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS 31 188 0.0001903 0.003116
285 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 124 1087 0.0001914 0.003116
286 NEURON PROJECTION GUIDANCE 33 205 0.0001915 0.003116
287 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 20 100 0.0001936 0.003138
288 WOUND HEALING 62 470 0.0002092 0.00338
289 FEMALE SEX DIFFERENTIATION 22 116 0.0002128 0.003426
290 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 27 156 0.0002151 0.00345
291 REGULATION OF EXTENT OF CELL GROWTH 20 101 0.0002227 0.003561
292 REGULATION OF CARDIAC MUSCLE CELL CONTRACTION 9 27 0.0002241 0.00357
293 REGULATION OF ENDOCYTOSIS 32 199 0.0002424 0.003849
294 REGULATION OF ANDROGEN RECEPTOR SIGNALING PATHWAY 8 22 0.0002538 0.003976
295 POSITIVE REGULATION OF MUSCLE HYPERTROPHY 8 22 0.0002538 0.003976
296 CENTRAL NERVOUS SYSTEM PROJECTION NEURON AXONOGENESIS 8 22 0.0002538 0.003976
297 POSITIVE REGULATION OF CARDIAC MUSCLE HYPERTROPHY 8 22 0.0002538 0.003976
298 HIPPOCAMPUS DEVELOPMENT 16 73 0.0002782 0.004344
299 REGULATION OF INTRACELLULAR TRANSPORT 77 621 0.0002827 0.0044
300 PEPTIDYL THREONINE MODIFICATION 12 46 0.0002909 0.004512
301 RESPONSE TO MECHANICAL STIMULUS 33 210 0.000302 0.004669
302 EMBRYO DEVELOPMENT 104 894 0.0003092 0.004764
303 POSITIVE REGULATION OF PROTEIN KINASE B SIGNALING 17 81 0.0003145 0.00483
304 NEURON PROJECTION EXTENSION 13 53 0.0003192 0.004854
305 MYELOID LEUKOCYTE DIFFERENTIATION 19 96 0.0003188 0.004854
306 CELLULAR MONOVALENT INORGANIC CATION HOMEOSTASIS 19 96 0.0003188 0.004854
307 RESPONSE TO FLUID SHEAR STRESS 10 34 0.0003223 0.004885
308 CARBOHYDRATE DERIVATIVE BIOSYNTHETIC PROCESS 74 595 0.0003367 0.005081
309 POSITIVE REGULATION OF WNT SIGNALING PATHWAY 26 152 0.0003374 0.005081
310 DIVALENT INORGANIC ANION HOMEOSTASIS 6 13 0.0003422 0.00512
311 REGULATION OF CYTOPLASMIC TRANSLATION 6 13 0.0003422 0.00512
312 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 25 144 0.0003449 0.005143
313 PEPTIDYL TYROSINE MODIFICATION 30 186 0.0003539 0.00526
314 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 76 616 0.0003589 0.005318
315 POSITIVE REGULATION OF MAPK CASCADE 61 470 0.0003623 0.005334
316 POSITIVE REGULATION OF RECEPTOR MEDIATED ENDOCYTOSIS 12 47 0.0003613 0.005334
317 CELL DEATH 114 1001 0.0003672 0.00539
318 ARTERY DEVELOPMENT 16 75 0.0003849 0.005632
319 ARP2 3 COMPLEX MEDIATED ACTIN NUCLEATION 7 18 0.000387 0.005645
320 OVULATION CYCLE 21 113 0.000391 0.005686
321 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 33 213 0.0003928 0.005693
322 REGULATION OF PROTEIN KINASE B SIGNALING 22 121 0.0003954 0.005713
323 REGULATION OF CELL JUNCTION ASSEMBLY 15 68 0.0003969 0.005718
324 PEPTIDYL AMINO ACID MODIFICATION 98 841 0.0004311 0.006192
325 CELL CYCLE G2 M PHASE TRANSITION 24 138 0.000437 0.006256
326 POSITIVE REGULATION OF HEMOPOIESIS 27 163 0.0004445 0.006333
327 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 22 122 0.0004451 0.006333
328 CELLULAR RESPONSE TO HORMONE STIMULUS 69 552 0.0004571 0.006485
329 WNT SIGNALING PATHWAY 48 351 0.0004653 0.00658
330 CELL PROLIFERATION 81 672 0.0004832 0.006813
331 REGULATION OF CELL CELL ADHESION 51 380 0.0004913 0.006906
332 POSITIVE REGULATION OF OSSIFICATION 17 84 0.0004927 0.006906
333 NEGATIVE REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 23 131 0.0004957 0.006906
334 PROTEIN STABILIZATION 23 131 0.0004957 0.006906
335 CELLULAR RESPONSE TO ALCOHOL 21 115 0.0004994 0.006936
336 ACTIN NUCLEATION 8 24 0.0005019 0.006951
337 STRIATED MUSCLE CELL DIFFERENTIATION 28 173 0.0005169 0.007137
338 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 86 724 0.0005236 0.007207
339 REGULATION OF NUCLEOTIDE CATABOLIC PROCESS 10 36 0.0005357 0.007353
340 RESPONSE TO EPIDERMAL GROWTH FACTOR 9 30 0.0005441 0.007379
341 NEGATIVE REGULATION OF CELL MATRIX ADHESION 9 30 0.0005441 0.007379
342 LIMBIC SYSTEM DEVELOPMENT 19 100 0.0005456 0.007379
343 SINGLE ORGANISM CELLULAR LOCALIZATION 103 898 0.0005441 0.007379
344 LAMELLIPODIUM ASSEMBLY 9 30 0.0005441 0.007379
345 MITOTIC CELL CYCLE 90 766 0.0005598 0.007501
346 MEMBRANE DEPOLARIZATION DURING CARDIAC MUSCLE CELL ACTION POTENTIAL 6 14 0.0005567 0.007501
347 INOSITOL LIPID MEDIATED SIGNALING 22 124 0.000561 0.007501
348 RESPONSE TO REACTIVE OXYGEN SPECIES 30 191 0.0005592 0.007501
349 REGULATION OF CARDIAC MUSCLE CELL ACTION POTENTIAL 7 19 0.0005688 0.00754
350 CELLULAR SODIUM ION HOMEOSTASIS 7 19 0.0005688 0.00754
351 MONOVALENT INORGANIC ANION HOMEOSTASIS 7 19 0.0005688 0.00754
352 ACTIN FILAMENT BASED MOVEMENT 18 93 0.0006002 0.007911
353 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 33 218 0.0005985 0.007911
354 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 35 236 0.0006108 0.007984
355 POSITIVE REGULATION OF ION TRANSPORT 35 236 0.0006108 0.007984
356 REGULATION OF RECEPTOR MEDIATED ENDOCYTOSIS 16 78 0.0006104 0.007984
357 CEREBRAL CORTEX CELL MIGRATION 11 43 0.0006191 0.008047
358 CHONDROITIN SULFATE PROTEOGLYCAN METABOLIC PROCESS 11 43 0.0006191 0.008047
359 GLIOGENESIS 28 175 0.0006235 0.008059
360 RESPONSE TO PURINE CONTAINING COMPOUND 26 158 0.0006223 0.008059
361 KIDNEY EPITHELIUM DEVELOPMENT 22 125 0.0006282 0.008097
362 MORPHOGENESIS OF A BRANCHING STRUCTURE 27 167 0.0006553 0.008424
363 REGULATION OF CYTOPLASMIC TRANSPORT 61 481 0.0006603 0.008464
364 AXON EXTENSION 10 37 0.0006798 0.00869
365 CELLULAR RESPONSE TO EPIDERMAL GROWTH FACTOR STIMULUS 8 25 0.0006846 0.008703
366 REGULATION OF ACTIVIN RECEPTOR SIGNALING PATHWAY 8 25 0.0006846 0.008703
367 REGULATION OF MAPK CASCADE 79 660 0.0006938 0.008796
368 RAS PROTEIN SIGNAL TRANSDUCTION 24 143 0.0007421 0.009383
369 MUSCLE TISSUE DEVELOPMENT 39 275 0.0007554 0.009525
370 HOMEOSTATIC PROCESS 144 1337 0.0007626 0.009572
371 REGULATION OF PROTEIN STABILITY 33 221 0.0007632 0.009572
372 REGULATION OF MUSCLE SYSTEM PROCESS 30 195 0.0007925 0.009913
NumGOOverlapSizeP ValueAdj. P Value
1 CYTOSKELETAL PROTEIN BINDING 134 819 1.679e-14 1.56e-11
2 ENZYME BINDING 230 1737 2.997e-13 1.392e-10
3 MACROMOLECULAR COMPLEX BINDING 192 1399 1.476e-12 4.571e-10
4 PROTEIN COMPLEX BINDING 139 935 9.012e-12 2.093e-09
5 RIBONUCLEOTIDE BINDING 233 1860 5.939e-11 1.103e-08
6 PROTEIN KINASE ACTIVITY 101 640 2.667e-10 4.13e-08
7 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 62 328 7.876e-10 1.045e-07
8 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 97 629 2.107e-09 2.447e-07
9 KINASE ACTIVITY 119 842 6.582e-09 6.794e-07
10 ADENYL NUCLEOTIDE BINDING 188 1514 1.08e-08 1.003e-06
11 ACTIN BINDING 67 393 1.355e-08 1.144e-06
12 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 57 315 1.929e-08 1.493e-06
13 KINASE BINDING 91 606 2.466e-08 1.762e-06
14 REGULATORY REGION NUCLEIC ACID BINDING 114 818 3.012e-08 1.999e-06
15 PROTEIN SERINE THREONINE KINASE ACTIVITY 72 445 3.642e-08 2.255e-06
16 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 44 226 9.176e-08 5.328e-06
17 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 129 992 2.147e-07 1.173e-05
18 RECEPTOR BINDING 177 1476 3.398e-07 1.753e-05
19 MICROTUBULE BINDING 39 201 5.307e-07 2.595e-05
20 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 84 588 7.354e-07 3.416e-05
21 MOLECULAR FUNCTION REGULATOR 162 1353 1.226e-06 5.324e-05
22 DOUBLE STRANDED DNA BINDING 102 764 1.261e-06 5.324e-05
23 TRANSCRIPTION FACTOR BINDING 76 524 1.383e-06 5.586e-05
24 TUBULIN BINDING 47 273 1.449e-06 5.61e-05
25 SEQUENCE SPECIFIC DNA BINDING 129 1037 2.342e-06 8.419e-05
26 CORE PROMOTER PROXIMAL REGION DNA BINDING 58 371 2.356e-06 8.419e-05
27 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 33 168 2.925e-06 0.0001006
28 PROTEIN DIMERIZATION ACTIVITY 138 1149 6.726e-06 0.0002232
29 PROTEIN DOMAIN SPECIFIC BINDING 84 624 7.958e-06 0.0002549
30 ENHANCER BINDING 21 93 2.064e-05 0.0006244
31 ENZYME ACTIVATOR ACTIVITY 66 471 2.084e-05 0.0006244
32 NUCLEOSIDE TRIPHOSPHATASE REGULATOR ACTIVITY 50 329 2.484e-05 0.0006993
33 GLYCOPROTEIN BINDING 22 101 2.414e-05 0.0006993
34 CALMODULIN BINDING 32 179 3.062e-05 0.0008367
35 IDENTICAL PROTEIN BINDING 140 1209 3.631e-05 0.0009638
36 PROTEIN HOMODIMERIZATION ACTIVITY 91 722 4.504e-05 0.001162
37 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 138 1199 5.514e-05 0.00138
38 GROWTH FACTOR RECEPTOR BINDING 25 129 5.644e-05 0.00138
39 TRANSCRIPTION COACTIVATOR ACTIVITY 45 296 6.133e-05 0.001461
40 NITRIC OXIDE SYNTHASE BINDING 8 19 7.528e-05 0.001748
41 STEROID HORMONE RECEPTOR BINDING 18 81 9.817e-05 0.002224
42 MRNA 3 UTR BINDING 13 48 0.0001084 0.002398
43 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 21 105 0.0001354 0.002925
44 ENZYME REGULATOR ACTIVITY 112 959 0.0001573 0.003321
45 SODIUM CHANNEL REGULATOR ACTIVITY 10 32 0.000185 0.003819
46 ANDROGEN RECEPTOR BINDING 11 39 0.000246 0.004967
47 ION CHANNEL BINDING 21 111 0.0003038 0.005921
48 CALMODULIN DEPENDENT PROTEIN KINASE ACTIVITY 9 28 0.0003059 0.005921
49 LIGAND DEPENDENT NUCLEAR RECEPTOR TRANSCRIPTION COACTIVATOR ACTIVITY 13 53 0.0003192 0.006052
50 CORE PROMOTER BINDING 26 152 0.0003374 0.006269
51 SNARE BINDING 23 128 0.000352 0.006413
52 SYNTAXIN 1 BINDING 7 18 0.000387 0.006914
53 ACTIN FILAMENT BINDING 22 121 0.0003954 0.006919
54 PHOSPHATASE BINDING 27 162 0.0004022 0.006919
55 ATPASE BINDING 16 76 0.0004504 0.007608
56 GUANYL NUCLEOTIDE BINDING 52 390 0.0005082 0.008284
57 EPHRIN RECEPTOR BINDING 8 24 0.0005019 0.008284
58 PHOSPHATIDYLINOSITOL 3 KINASE BINDING 9 30 0.0005441 0.008714
59 SYNTAXIN BINDING 18 93 0.0006002 0.00945
NumGOOverlapSizeP ValueAdj. P Value
1 CELL JUNCTION 177 1151 3.668e-16 2.142e-13
2 ANCHORING JUNCTION 92 489 8.099e-14 2.365e-11
3 CELL SUBSTRATE JUNCTION 79 398 2.682e-13 5.22e-11
4 CELL PROJECTION 232 1786 1.734e-12 2.532e-10
5 MEMBRANE REGION 157 1134 1.032e-10 1.206e-08
6 NEURON PROJECTION 134 942 4.526e-10 3.837e-08
7 GOLGI APPARATUS 187 1445 4.599e-10 3.837e-08
8 NEURON PART 166 1265 1.76e-09 1.285e-07
9 GOLGI APPARATUS PART 124 893 9.046e-09 5.87e-07
10 CELL CELL JUNCTION 66 383 1.126e-08 6.576e-07
11 SYNAPSE 108 754 1.645e-08 8.736e-07
12 CELL LEADING EDGE 61 350 2.624e-08 1.277e-06
13 CYTOSKELETON 227 1967 1.408e-07 6.117e-06
14 GOLGI MEMBRANE 99 703 1.513e-07 6.117e-06
15 PLASMA MEMBRANE REGION 123 929 1.571e-07 6.117e-06
16 INTRACELLULAR VESICLE 155 1259 4.034e-07 1.472e-05
17 ACTIN CYTOSKELETON 68 444 7.029e-07 2.415e-05
18 MICROTUBULE 63 405 1.044e-06 3.388e-05
19 MEMBRANE MICRODOMAIN 49 288 1.244e-06 3.823e-05
20 COATED PIT 19 67 1.413e-06 4.126e-05
21 SOMATODENDRITIC COMPARTMENT 89 650 2.134e-06 5.935e-05
22 CELL CELL CONTACT ZONE 18 64 3.033e-06 8.039e-05
23 COATED VESICLE MEMBRANE 29 139 3.304e-06 8.039e-05
24 SYNAPSE PART 84 610 3.283e-06 8.039e-05
25 COATED VESICLE 41 234 4.241e-06 9.906e-05
26 DENDRITE 66 451 4.986e-06 0.000112
27 VACUOLE 141 1180 6.962e-06 0.0001506
28 POSTSYNAPSE 57 378 8.805e-06 0.0001837
29 CELL PROJECTION PART 117 946 9.158e-06 0.0001844
30 TRANS GOLGI NETWORK 35 193 9.637e-06 0.0001876
31 ENDOSOME 101 793 1.123e-05 0.0002055
32 ORGANELLE SUBCOMPARTMENT 49 311 1.126e-05 0.0002055
33 INTRINSIC COMPONENT OF PLASMA MEMBRANE 183 1649 2.833e-05 0.0005014
34 CYTOSKELETAL PART 162 1436 3.59e-05 0.0006167
35 EXCITATORY SYNAPSE 34 197 3.73e-05 0.0006224
36 ENDOCYTIC VESICLE 41 256 3.871e-05 0.000628
37 INTERCALATED DISC 14 51 5.05e-05 0.0007563
38 APICAL JUNCTION COMPLEX 25 128 4.935e-05 0.0007563
39 BASAL PART OF CELL 14 51 5.05e-05 0.0007563
40 CYTOPLASMIC REGION 44 287 6.022e-05 0.0008792
41 MEMBRANE PROTEIN COMPLEX 120 1020 6.744e-05 0.0009605
42 LAMELLIPODIUM 30 172 8.545e-05 0.001181
43 RUFFLE 28 156 8.693e-05 0.001181
44 CLATHRIN COATED VESICLE 28 157 9.752e-05 0.001274
45 CLATHRIN COATED VESICLE MEMBRANE 18 81 9.817e-05 0.001274
46 ARP2 3 PROTEIN COMPLEX 6 11 0.0001067 0.001354
47 KINESIN COMPLEX 14 55 0.000124 0.00154
48 BASOLATERAL PLASMA MEMBRANE 34 211 0.0001514 0.001804
49 NEURON SPINE 23 121 0.0001492 0.001804
50 CELL CORTEX 37 238 0.0001684 0.001967
51 CLATHRIN COATED ENDOCYTIC VESICLE 15 65 0.0002352 0.002694
52 VESICLE MEMBRANE 66 512 0.0002578 0.002895
53 CYTOPLASMIC VESICLE PART 75 601 0.000278 0.003063
54 CELL PROJECTION MEMBRANE 43 298 0.0002873 0.003107
55 VACUOLAR PART 84 694 0.0003356 0.003563
56 EARLY ENDOSOME 43 301 0.0003572 0.003725
57 MICROTUBULE ASSOCIATED COMPLEX 25 145 0.0003843 0.003938
58 COSTAMERE 7 19 0.0005688 0.005727
59 ER TO GOLGI TRANSPORT VESICLE 15 71 0.0006457 0.005985
60 MICROTUBULE CYTOSKELETON 119 1068 0.0006366 0.005985
61 NUCLEAR CHROMATIN 41 291 0.0006417 0.005985
62 EXTRACELLULAR MATRIX COMPONENT 22 125 0.0006282 0.005985
63 SARCOLEMMA 22 125 0.0006282 0.005985
64 SUPRAMOLECULAR FIBER 80 670 0.0006925 0.006319
65 BRUSH BORDER 19 102 0.0007038 0.006324
66 CELL DIVISION SITE 12 52 0.0009668 0.008555
67 PLASMA MEMBRANE PROTEIN COMPLEX 63 510 0.001067 0.009304
68 GLYCOPROTEIN COMPLEX 7 21 0.001132 0.009719
69 BASAL PLASMA MEMBRANE 9 33 0.001167 0.00988

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04510_Focal_adhesion 41 387 0.06702 1
2 hsa04010_MAPK_signaling_pathway 38 387 0.1655 1
3 hsa04810_Regulation_of_actin_cytoskeleton 35 387 0.3324 1
4 hsa04144_Endocytosis 34 387 0.401 1
5 hsa04020_Calcium_signaling_pathway 29 387 0.7544 1
6 hsa04062_Chemokine_signaling_pathway 28 387 0.8111 1
7 hsa04360_Axon_guidance 27 387 0.8593 1
8 hsa04114_Oocyte_meiosis 23 387 0.9701 1
9 hsa04310_Wnt_signaling_pathway 23 387 0.9701 1
10 hsa04530_Tight_junction 23 387 0.9701 1
11 hsa04630_Jak.STAT_signaling_pathway 22 387 0.9817 1
12 hsa04972_Pancreatic_secretion 22 387 0.9817 1
13 hsa04514_Cell_adhesion_molecules_.CAMs. 21 387 0.9893 1
14 hsa04670_Leukocyte_transendothelial_migration 21 387 0.9893 1
15 hsa00230_Purine_metabolism 20 387 0.994 1
16 hsa04540_Gap_junction 19 387 0.9968 1
17 hsa04666_Fc_gamma_R.mediated_phagocytosis 19 387 0.9968 1
18 hsa04912_GnRH_signaling_pathway 19 387 0.9968 1
19 hsa04916_Melanogenesis 19 387 0.9968 1
20 hsa04971_Gastric_acid_secretion 19 387 0.9968 1
21 hsa04120_Ubiquitin_mediated_proteolysis 18 387 0.9984 1
22 hsa04270_Vascular_smooth_muscle_contraction 18 387 0.9984 1
23 hsa04012_ErbB_signaling_pathway 17 387 0.9993 1
24 hsa04722_Neurotrophin_signaling_pathway 17 387 0.9993 1
25 hsa04970_Salivary_secretion 17 387 0.9993 1
26 hsa04974_Protein_digestion_and_absorption 16 387 0.9997 1
27 hsa04110_Cell_cycle 14 387 0.9999 1
28 hsa04141_Protein_processing_in_endoplasmic_reticulum 14 387 0.9999 1
29 hsa04520_Adherens_junction 14 387 0.9999 1
30 hsa04660_T_cell_receptor_signaling_pathway 15 387 0.9999 1
31 hsa04720_Long.term_potentiation 14 387 0.9999 1
32 hsa04910_Insulin_signaling_pathway 14 387 0.9999 1
33 hsa04914_Progesterone.mediated_oocyte_maturation 15 387 0.9999 1
34 hsa04960_Aldosterone.regulated_sodium_reabsorption 14 387 0.9999 1
35 hsa00010_Glycolysis_._Gluconeogenesis 5 387 1 1
36 hsa00020_Citrate_cycle_.TCA_cycle. 5 387 1 1
37 hsa00030_Pentose_phosphate_pathway 4 387 1 1
38 hsa00040_Pentose_and_glucuronate_interconversions 2 387 1 1
39 hsa00051_Fructose_and_mannose_metabolism 2 387 1 1
40 hsa00053_Ascorbate_and_aldarate_metabolism 2 387 1 1
41 hsa00071_Fatty_acid_metabolism 4 387 1 1
42 hsa00140_Steroid_hormone_biosynthesis 6 387 1 1
43 hsa00190_Oxidative_phosphorylation 5 387 1 1
44 hsa00240_Pyrimidine_metabolism 8 387 1 1
45 hsa00250_Alanine._aspartate_and_glutamate_metabolism 2 387 1 1
46 hsa00260_Glycine._serine_and_threonine_metabolism 3 387 1 1
47 hsa00280_Valine._leucine_and_isoleucine_degradation 5 387 1 1
48 hsa00290_Valine._leucine_and_isoleucine_biosynthesis 2 387 1 1
49 hsa00310_Lysine_degradation 3 387 1 1
50 hsa00340_Histidine_metabolism 3 387 1 1
51 hsa00350_Tyrosine_metabolism 4 387 1 1
52 hsa00380_Tryptophan_metabolism 2 387 1 1
53 hsa00410_beta.Alanine_metabolism 2 387 1 1
54 hsa00450_Selenocompound_metabolism 2 387 1 1
55 hsa00480_Glutathione_metabolism 2 387 1 1
56 hsa00500_Starch_and_sucrose_metabolism 4 387 1 1
57 hsa00510_N.Glycan_biosynthesis 6 387 1 1
58 hsa00511_Other_glycan_degradation 2 387 1 1
59 hsa00512_Mucin_type_O.Glycan_biosynthesis 5 387 1 1
60 hsa00514_Other_types_of_O.glycan_biosynthesis 4 387 1 1
61 hsa00520_Amino_sugar_and_nucleotide_sugar_metabolism 6 387 1 1
62 hsa00531_Glycosaminoglycan_degradation 2 387 1 1
63 hsa00532_Glycosaminoglycan_biosynthesis_._chondroitin_sulfate 5 387 1 1
64 hsa00534_Glycosaminoglycan_biosynthesis_._heparan_sulfate 5 387 1 1
65 hsa00561_Glycerolipid_metabolism 3 387 1 1
66 hsa00562_Inositol_phosphate_metabolism 5 387 1 1
67 hsa00563_Glycosylphosphatidylinositol.GPI..anchor_biosynthesis 2 387 1 1
68 hsa00564_Glycerophospholipid_metabolism 7 387 1 1
69 hsa00565_Ether_lipid_metabolism 3 387 1 1
70 hsa00590_Arachidonic_acid_metabolism 2 387 1 1
71 hsa00600_Sphingolipid_metabolism 2 387 1 1
72 hsa00601_Glycosphingolipid_biosynthesis_._lacto_and_neolacto_series 2 387 1 1
73 hsa00603_Glycosphingolipid_biosynthesis_._globo_series 2 387 1 1
74 hsa00630_Glyoxylate_and_dicarboxylate_metabolism 2 387 1 1
75 hsa00640_Propanoate_metabolism 3 387 1 1
76 hsa00670_One_carbon_pool_by_folate 2 387 1 1
77 hsa00750_Vitamin_B6_metabolism 2 387 1 1
78 hsa00760_Nicotinate_and_nicotinamide_metabolism 3 387 1 1
79 hsa00770_Pantothenate_and_CoA_biosynthesis 5 387 1 1
80 hsa00830_Retinol_metabolism 4 387 1 1
81 hsa00860_Porphyrin_and_chlorophyll_metabolism 3 387 1 1
82 hsa00900_Terpenoid_backbone_biosynthesis 2 387 1 1
83 hsa00910_Nitrogen_metabolism 2 387 1 1
84 hsa00920_Sulfur_metabolism 2 387 1 1
85 hsa00970_Aminoacyl.tRNA_biosynthesis 3 387 1 1
86 hsa00980_Metabolism_of_xenobiotics_by_cytochrome_P450 3 387 1 1
87 hsa00982_Drug_metabolism_._cytochrome_P450 3 387 1 1
88 hsa00983_Drug_metabolism_._other_enzymes 5 387 1 1
89 hsa01040_Biosynthesis_of_unsaturated_fatty_acids 2 387 1 1
90 hsa02010_ABC_transporters 7 387 1 1
91 hsa03008_Ribosome_biogenesis_in_eukaryotes 8 387 1 1
92 hsa03013_RNA_transport 6 387 1 1
93 hsa03015_mRNA_surveillance_pathway 10 387 1 1
94 hsa03018_RNA_degradation 3 387 1 1
95 hsa03020_RNA_polymerase 2 387 1 1
96 hsa03022_Basal_transcription_factors 2 387 1 1
97 hsa03040_Spliceosome 4 387 1 1
98 hsa03050_Proteasome 2 387 1 1
99 hsa03320_PPAR_signaling_pathway 7 387 1 1
100 hsa03420_Nucleotide_excision_repair 2 387 1 1
101 hsa03430_Mismatch_repair 2 387 1 1
102 hsa04070_Phosphatidylinositol_signaling_system 10 387 1 1
103 hsa04115_p53_signaling_pathway 13 387 1 1
104 hsa04130_SNARE_interactions_in_vesicular_transport 7 387 1 1
105 hsa04140_Regulation_of_autophagy 4 387 1 1
106 hsa04142_Lysosome 12 387 1 1
107 hsa04145_Phagosome 13 387 1 1
108 hsa04146_Peroxisome 9 387 1 1
109 hsa04150_mTOR_signaling_pathway 10 387 1 1
110 hsa04210_Apoptosis 13 387 1 1
111 hsa04260_Cardiac_muscle_contraction 10 387 1 1
112 hsa04320_Dorso.ventral_axis_formation 5 387 1 1
113 hsa04330_Notch_signaling_pathway 2 387 1 1
114 hsa04340_Hedgehog_signaling_pathway 7 387 1 1
115 hsa04350_TGF.beta_signaling_pathway 10 387 1 1
116 hsa04370_VEGF_signaling_pathway 11 387 1 1
117 hsa04380_Osteoclast_differentiation 12 387 1 1
118 hsa04512_ECM.receptor_interaction 13 387 1 1
119 hsa04610_Complement_and_coagulation_cascades 2 387 1 1
120 hsa04612_Antigen_processing_and_presentation 8 387 1 1
121 hsa04614_Renin.angiotensin_system 2 387 1 1
122 hsa04620_Toll.like_receptor_signaling_pathway 11 387 1 1
123 hsa04621_NOD.like_receptor_signaling_pathway 6 387 1 1
124 hsa04622_RIG.I.like_receptor_signaling_pathway 2 387 1 1
125 hsa04623_Cytosolic_DNA.sensing_pathway 3 387 1 1
126 hsa04640_Hematopoietic_cell_lineage 13 387 1 1
127 hsa04650_Natural_killer_cell_mediated_cytotoxicity 12 387 1 1
128 hsa04662_B_cell_receptor_signaling_pathway 11 387 1 1
129 hsa04664_Fc_epsilon_RI_signaling_pathway 9 387 1 1
130 hsa04672_Intestinal_immune_network_for_IgA_production 2 387 1 1
131 hsa04710_Circadian_rhythm_._mammal 6 387 1 1
132 hsa04730_Long.term_depression 12 387 1 1
133 hsa04740_Olfactory_transduction 7 388 1 1
134 hsa04742_Taste_transduction 2 387 1 1
135 hsa04920_Adipocytokine_signaling_pathway 8 387 1 1
136 hsa04962_Vasopressin.regulated_water_reabsorption 9 387 1 1
137 hsa04964_Proximal_tubule_bicarbonate_reclamation 4 387 1 1
138 hsa04966_Collecting_duct_acid_secretion 3 387 1 1
139 hsa04973_Carbohydrate_digestion_and_absorption 9 387 1 1
140 hsa04976_Bile_secretion 13 387 1 1

Quest ID: c69f8c410fba81a12304b6ab2d8c277d