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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-27a-3p A1CF -0.37 0.00876 -0.98 1.0E-5 MirTarget -0.55 0 NA
2 hsa-miR-27a-3p ABAT -0.37 0.00876 -2.16 0 MirTarget -0.5 0 NA
3 hsa-miR-27a-3p ABCA1 -0.37 0.00876 -1.1 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.15 0.00176 NA
4 hsa-miR-27a-3p ABHD6 -0.37 0.00876 -1.31 0 miRNATAP -0.41 0 NA
5 hsa-miR-27a-3p AGGF1 -0.37 0.00876 0.14 0.03026 miRNATAP -0.12 0 24462738 Role of microRNA 27a in down regulation of angiogenic factor AGGF1 under hypoxia associated with high grade bladder urothelial carcinoma; Hypoxia-induced down-regulation of AGGF1 was mediated by miR-27a; Overexpression of miR-27a suppressed AGGF1 expression through translational inhibition but not by RNA degradation; Moreover the hypoxia-induced decrease of AGGF1 expression disappeared after miR-27a expression was inhibited
6 hsa-miR-27a-3p AGPAT3 -0.37 0.00876 -0.18 0.05507 miRNATAP -0.14 1.0E-5 NA
7 hsa-miR-27a-3p AKIRIN2 -0.37 0.00876 -0.26 0.00807 miRNATAP -0.12 0.00021 NA
8 hsa-miR-27a-3p ALCAM -0.37 0.00876 0.24 0.05364 MirTarget -0.16 0.00029 NA
9 hsa-miR-27a-3p ALDH9A1 -0.37 0.00876 -1.02 0 miRNAWalker2 validate -0.22 0 NA
10 hsa-miR-27a-3p ALG9 -0.37 0.00876 0.16 0.03963 MirTarget -0.12 0 NA
11 hsa-miR-27a-3p APOOL -0.37 0.00876 -0.42 0.00899 MirTarget -0.11 0.04681 NA
12 hsa-miR-27a-3p AQP11 -0.37 0.00876 -0.63 0.00064 MirTarget; miRNATAP -0.58 0 NA
13 hsa-miR-27a-3p ARHGAP32 -0.37 0.00876 -0.2 0.09921 mirMAP -0.11 0.00903 NA
14 hsa-miR-27a-3p ARID4A -0.37 0.00876 -0.9 0 miRNATAP -0.11 0.00891 NA
15 hsa-miR-27a-3p ARIH2 -0.37 0.00876 0.34 0 miRNATAP -0.11 0 NA
16 hsa-miR-27a-3p ARL4D -0.37 0.00876 -0.85 2.0E-5 miRNATAP -0.45 0 NA
17 hsa-miR-27a-3p ARL6IP1 -0.37 0.00876 -0.85 0 miRNAWalker2 validate -0.11 0.00302 NA
18 hsa-miR-27a-3p ARNTL -0.37 0.00876 -0.35 0.02331 miRNATAP -0.2 0.00018 NA
19 hsa-miR-27a-3p ATP7B -0.37 0.00876 -0.73 2.0E-5 miRNAWalker2 validate -0.41 0 NA
20 hsa-miR-27a-3p BMI1 -0.37 0.00876 0.21 0.02579 miRNAWalker2 validate -0.18 0 NA
21 hsa-miR-27a-3p BRPF3 -0.37 0.00876 0.35 0.00299 MirTarget; miRNATAP -0.22 0 NA
22 hsa-miR-27a-3p BRWD3 -0.37 0.00876 0.1 0.5367 MirTarget; miRNATAP -0.13 0.01423 NA
23 hsa-miR-27a-3p BSN -0.37 0.00876 0.94 2.0E-5 mirMAP -0.49 0 NA
24 hsa-miR-27a-3p C16orf52 -0.37 0.00876 -0.5 0 miRNATAP -0.15 2.0E-5 NA
25 hsa-miR-27a-3p CABLES2 -0.37 0.00876 0.82 0 miRNATAP -0.18 4.0E-5 NA
26 hsa-miR-27a-3p CACNB2 -0.37 0.00876 -0.29 0.15115 MirTarget; miRNATAP -0.17 0.01799 NA
27 hsa-miR-27a-3p CADM1 -0.37 0.00876 -0.03 0.88629 MirTarget; miRNATAP -0.39 0 NA
28 hsa-miR-27a-3p CALM3 -0.37 0.00876 0.21 0.01527 miRNATAP -0.1 0.00043 NA
29 hsa-miR-27a-3p CCDC71 -0.37 0.00876 0.07 0.37322 MirTarget; miRNATAP -0.1 9.0E-5 NA
30 hsa-miR-27a-3p CCNC -0.37 0.00876 -0.3 0.00149 MirTarget -0.1 0.0015 NA
31 hsa-miR-27a-3p CCNG1 -0.37 0.00876 -0.05 0.64033 MirTarget; miRNATAP -0.28 0 NA
32 hsa-miR-27a-3p CCNY -0.37 0.00876 -0.02 0.71307 MirTarget; miRNATAP -0.14 0 NA
33 hsa-miR-27a-3p CDC14B -0.37 0.00876 -1.19 0 miRNATAP -0.28 1.0E-5 NA
34 hsa-miR-27a-3p CHKA -0.37 0.00876 1.03 0 miRNATAP -0.24 0 NA
35 hsa-miR-27a-3p CLCN5 -0.37 0.00876 -0.78 0 miRNATAP -0.24 0 NA
36 hsa-miR-27a-3p CLK2 -0.37 0.00876 0.92 0 miRNATAP -0.1 0.00183 NA
37 hsa-miR-27a-3p CPPED1 -0.37 0.00876 0.16 0.18491 MirTarget -0.32 0 NA
38 hsa-miR-27a-3p CTH -0.37 0.00876 -2.13 0 MirTarget; miRNATAP -0.53 0 NA
39 hsa-miR-27a-3p CUL1 -0.37 0.00876 -0.12 0.10228 miRNAWalker2 validate -0.1 4.0E-5 NA
40 hsa-miR-27a-3p CYTH1 -0.37 0.00876 0.1 0.17383 miRNATAP -0.22 0 NA
41 hsa-miR-27a-3p DCP2 -0.37 0.00876 0.26 0.00123 miRNATAP -0.11 6.0E-5 NA
42 hsa-miR-27a-3p DCUN1D4 -0.37 0.00876 -0.24 0.00352 MirTarget; miRNATAP -0.16 0 NA
43 hsa-miR-27a-3p DNAJB9 -0.37 0.00876 -0.63 0 miRNATAP -0.19 2.0E-5 NA
44 hsa-miR-27a-3p DVL2 -0.37 0.00876 0.93 0 miRNATAP -0.1 0.00527 NA
45 hsa-miR-27a-3p DYNLL2 -0.37 0.00876 -0.63 0 MirTarget -0.11 0.00507 NA
46 hsa-miR-27a-3p EBF3 -0.37 0.00876 1.74 0 MirTarget; miRNATAP -0.19 0.02249 NA
47 hsa-miR-27a-3p EDEM3 -0.37 0.00876 0.01 0.89915 MirTarget; miRNATAP -0.11 0.00394 NA
48 hsa-miR-27a-3p EI24 -0.37 0.00876 -0.75 0 miRNATAP -0.12 0.00041 NA
49 hsa-miR-27a-3p EIF5 -0.37 0.00876 -0.72 0 MirTarget -0.11 0.00044 NA
50 hsa-miR-27a-3p ELL2 -0.37 0.00876 -0.77 0 MirTarget; miRNATAP -0.37 0 NA
51 hsa-miR-27a-3p ELOVL6 -0.37 0.00876 -1.01 0 mirMAP -0.15 0.03932 NA
52 hsa-miR-27a-3p ERP44 -0.37 0.00876 -0.19 0.01254 mirMAP -0.1 4.0E-5 NA
53 hsa-miR-27a-3p EXOC8 -0.37 0.00876 0.11 0.17333 MirTarget -0.11 9.0E-5 NA
54 hsa-miR-27a-3p FAM120C -0.37 0.00876 -0.13 0.23093 mirMAP; miRNATAP -0.11 0.00529 NA
55 hsa-miR-27a-3p FAM134C -0.37 0.00876 0.11 0.21873 MirTarget -0.17 0 NA
56 hsa-miR-27a-3p FAM172A -0.37 0.00876 0.23 0.00597 MirTarget -0.1 0.00026 NA
57 hsa-miR-27a-3p FAM184A -0.37 0.00876 -0.01 0.95662 MirTarget -0.62 0 NA
58 hsa-miR-27a-3p FAM200B -0.37 0.00876 -0.06 0.51148 MirTarget -0.19 0 NA
59 hsa-miR-27a-3p FASN -0.37 0.00876 0.95 0 miRNATAP -0.37 0 NA
60 hsa-miR-27a-3p FOXN3 -0.37 0.00876 -0.43 6.0E-5 miRNATAP -0.25 0 NA
61 hsa-miR-27a-3p FOXO1 -0.37 0.00876 -1.85 0 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.12 0.03605 25897249; 25652374 Adipose tissue secreted miR 27a promotes liver cancer by targeting FOXO1 in obese individuals;The expression of miR-27a and FOXO1 in AsPC-1 cells was determined by real-time RT-PCR and Western blot respectively; Both GSPE and miR-27a inhibitor alone could up-regulate FOXO1 expression
62 hsa-miR-27a-3p FOXP4 -0.37 0.00876 0.4 7.0E-5 miRNAWalker2 validate; MirTarget; miRNATAP -0.12 0.0009 NA
63 hsa-miR-27a-3p FUBP3 -0.37 0.00876 -0.38 0 miRNATAP -0.11 0.00023 NA
64 hsa-miR-27a-3p GFOD1 -0.37 0.00876 -0.74 0 MirTarget -0.14 0.01018 NA
65 hsa-miR-27a-3p GLYATL1 -0.37 0.00876 -3.18 0 MirTarget -0.54 6.0E-5 NA
66 hsa-miR-27a-3p GPAM -0.37 0.00876 -0.47 0.0638 miRNAWalker2 validate; MirTarget; miRNATAP -0.67 0 NA
67 hsa-miR-27a-3p GPT2 -0.37 0.00876 -1.48 0 miRNAWalker2 validate; mirMAP -0.38 1.0E-5 NA
68 hsa-miR-27a-3p HIPK2 -0.37 0.00876 -0.24 0.08389 miRNAWalker2 validate; miRNATAP -0.2 2.0E-5 20646448; 20624637 2 A2780/Taxol cells transfection with inhibitors of miR-27a showed that the levels of MDR1 mRNA was decreased by 39% P-gp protein level 26+/-5% decreased than that in the NC group 43+/-7% HIPK2 protein level 30+/-6% increased than that in the NC group 19+/-4% the 50% inhibition concentration 0.5 micromol/L was less than that in the NC group 6.8 micromol/L apoptosis rate 32.5+/-3.6% was higher than that in the NC group 5.6+/-2.1% and there were significant differences between two groups all P<0.05; The expression of miR-27a is upregulated in A2780/Taxol cells which may regulate MDR1 and P-gp expression by targeting HIPK2;MiR 27a modulates MDR1/P glycoprotein expression by targeting HIPK2 in human ovarian cancer cells; Transfection of A2780/Taxol cells with the inhibitors of miR-27a decreased the expression of MDR1 mRNA and P-gp protein increased HIPK2 protein expression enhanced the sensitivity of A2780/taxol cells to paclitaxel increased paclitaxel-induced apoptosis and the fluorescence intensity of intracellular Rh-123; The deregulation of miR-27a may be involved in the development of drug resistance regulating the expression of MDR1/P-gp at least in part by targeting HIPK2 in ovarian cancer cells
69 hsa-miR-27a-3p HMGCR -0.37 0.00876 -0.03 0.86086 miRNATAP -0.37 0 NA
70 hsa-miR-27a-3p HORMAD2 -0.37 0.00876 -2.21 0 MirTarget; miRNATAP -0.33 0.02252 NA
71 hsa-miR-27a-3p HSPD1 -0.37 0.00876 0.07 0.42182 MirTarget -0.14 0 NA
72 hsa-miR-27a-3p IMPA1 -0.37 0.00876 0.15 0.15162 miRNAWalker2 validate -0.14 6.0E-5 NA
73 hsa-miR-27a-3p ING5 -0.37 0.00876 0.67 0 MirTarget; miRNATAP -0.19 0 NA
74 hsa-miR-27a-3p INSR -0.37 0.00876 -0.28 0.00786 miRNATAP -0.13 0.00032 NA
75 hsa-miR-27a-3p IPO9 -0.37 0.00876 0.7 0 mirMAP -0.13 1.0E-5 NA
76 hsa-miR-27a-3p IQGAP2 -0.37 0.00876 -1.1 0 MirTarget -0.4 0 NA
77 hsa-miR-27a-3p IRS1 -0.37 0.00876 -0.22 0.13754 MirTarget; miRNATAP -0.49 0 NA
78 hsa-miR-27a-3p KCTD21 -0.37 0.00876 -0.19 0.06162 miRNATAP -0.19 0 NA
79 hsa-miR-27a-3p KHSRP -0.37 0.00876 0.31 2.0E-5 miRNATAP -0.11 2.0E-5 NA
80 hsa-miR-27a-3p KLF12 -0.37 0.00876 -0.86 0 mirMAP -0.4 0 NA
81 hsa-miR-27a-3p KLF3 -0.37 0.00876 -0.61 0 miRNATAP -0.1 0.00033 NA
82 hsa-miR-27a-3p KLHDC3 -0.37 0.00876 0.39 0.0001 miRNATAP -0.23 0 NA
83 hsa-miR-27a-3p KLHL31 -0.37 0.00876 1.27 0 MirTarget -0.2 0.00255 NA
84 hsa-miR-27a-3p LARP4 -0.37 0.00876 -0.61 0 MirTarget; miRNATAP -0.19 0 NA
85 hsa-miR-27a-3p LIPT2 -0.37 0.00876 -0.01 0.92161 MirTarget -0.11 0.00972 NA
86 hsa-miR-27a-3p LPIN1 -0.37 0.00876 -0.14 0.37055 miRNATAP -0.22 2.0E-5 NA
87 hsa-miR-27a-3p LRRC58 -0.37 0.00876 -0.04 0.75979 mirMAP -0.14 0.0003 NA
88 hsa-miR-27a-3p LSM11 -0.37 0.00876 0.76 0 mirMAP -0.24 0 NA
89 hsa-miR-27a-3p LYSMD3 -0.37 0.00876 -0.5 0 miRNAWalker2 validate -0.11 0.00336 NA
90 hsa-miR-27a-3p MAD2L1BP -0.37 0.00876 0.17 0.04111 MirTarget -0.13 0 NA
91 hsa-miR-27a-3p MAGI3 -0.37 0.00876 -0.59 0 MirTarget; miRNATAP -0.17 0.00012 NA
92 hsa-miR-27a-3p MANEAL -0.37 0.00876 0.6 0.00094 miRNATAP -0.32 0 NA
93 hsa-miR-27a-3p MAP3K13 -0.37 0.00876 -0.45 0.05753 MirTarget -0.18 0.0253 NA
94 hsa-miR-27a-3p MAPK14 -0.37 0.00876 -0.14 0.04955 MirTarget; miRNATAP -0.14 0 NA
95 hsa-miR-27a-3p MBTD1 -0.37 0.00876 -0.15 0.10862 miRNAWalker2 validate -0.18 0 NA
96 hsa-miR-27a-3p MED13 -0.37 0.00876 -0.26 0.00586 MirTarget; miRNATAP -0.17 0 NA
97 hsa-miR-27a-3p MEPCE -0.37 0.00876 0.26 0.00176 miRNATAP -0.16 0 NA
98 hsa-miR-27a-3p MIER3 -0.37 0.00876 -0.29 0.00044 miRNAWalker2 validate; MirTarget; miRNATAP -0.14 0 NA
99 hsa-miR-27a-3p MOCS1 -0.37 0.00876 -0.56 3.0E-5 mirMAP -0.34 0 NA
100 hsa-miR-27a-3p MOCS3 -0.37 0.00876 0.06 0.43529 MirTarget -0.19 0 NA
101 hsa-miR-27a-3p MOSPD3 -0.37 0.00876 0.26 0.01944 miRNATAP -0.18 0 NA
102 hsa-miR-27a-3p MREG -0.37 0.00876 0.47 0.00032 MirTarget -0.17 0.00014 NA
103 hsa-miR-27a-3p MRPS14 -0.37 0.00876 0.43 0 miRNATAP -0.15 0 NA
104 hsa-miR-27a-3p MRPS25 -0.37 0.00876 0.02 0.84026 MirTarget -0.14 1.0E-5 NA
105 hsa-miR-27a-3p MTMR4 -0.37 0.00876 -0.2 0.11072 miRNATAP -0.37 0 NA
106 hsa-miR-27a-3p NDUFS4 -0.37 0.00876 0.14 0.21443 MirTarget -0.17 1.0E-5 NA
107 hsa-miR-27a-3p NEDD4 -0.37 0.00876 -0.21 0.20967 MirTarget; miRNATAP -0.38 0 NA
108 hsa-miR-27a-3p NFIA -0.37 0.00876 -0.92 0 mirMAP; miRNATAP -0.19 2.0E-5 NA
109 hsa-miR-27a-3p NLK -0.37 0.00876 0.22 0.00116 miRNATAP -0.15 0 NA
110 hsa-miR-27a-3p NR1D2 -0.37 0.00876 -0.43 4.0E-5 miRNATAP -0.14 0.00011 NA
111 hsa-miR-27a-3p NR5A2 -0.37 0.00876 -0.7 0.00021 miRNATAP -0.16 0.01488 NA
112 hsa-miR-27a-3p NRIP1 -0.37 0.00876 -0.83 0 MirTarget; miRNATAP -0.13 0.00088 NA
113 hsa-miR-27a-3p NSA2 -0.37 0.00876 0.15 0.0763 MirTarget -0.17 0 NA
114 hsa-miR-27a-3p NXT2 -0.37 0.00876 0.28 0.01042 MirTarget; miRNATAP -0.14 0.00031 NA
115 hsa-miR-27a-3p OAF -0.37 0.00876 -1.07 0 MirTarget -0.23 0 NA
116 hsa-miR-27a-3p ONECUT2 -0.37 0.00876 0.12 0.55138 miRNATAP -0.49 0 NA
117 hsa-miR-27a-3p PAIP2 -0.37 0.00876 0.06 0.39477 MirTarget -0.14 0 NA
118 hsa-miR-27a-3p PALM2 -0.37 0.00876 -2.08 0 MirTarget -0.18 0.03311 NA
119 hsa-miR-27a-3p PANK1 -0.37 0.00876 -1.79 0 miRNATAP -0.37 0 NA
120 hsa-miR-27a-3p PAQR9 -0.37 0.00876 0.14 0.51216 MirTarget -0.54 0 NA
121 hsa-miR-27a-3p PATZ1 -0.37 0.00876 0.09 0.32877 miRNATAP -0.15 0 NA
122 hsa-miR-27a-3p PDE3B -0.37 0.00876 -0.99 0 MirTarget -0.33 0 NA
123 hsa-miR-27a-3p PDHX -0.37 0.00876 -0.36 0 MirTarget; miRNATAP -0.16 0 NA
124 hsa-miR-27a-3p PDIA5 -0.37 0.00876 -0.87 0 MirTarget; miRNATAP -0.11 0.00814 NA
125 hsa-miR-27a-3p PDK4 -0.37 0.00876 -2.11 0 MirTarget -0.4 6.0E-5 NA
126 hsa-miR-27a-3p PDPK1 -0.37 0.00876 0.31 0.01459 miRNATAP -0.13 0.00358 NA
127 hsa-miR-27a-3p PEG10 -0.37 0.00876 1.32 0.03061 MirTarget -0.84 6.0E-5 NA
128 hsa-miR-27a-3p PGAP1 -0.37 0.00876 0.01 0.92638 miRNATAP -0.11 0.01339 NA
129 hsa-miR-27a-3p PHB -0.37 0.00876 0.23 0.01203 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.13 6.0E-5 22505583 Androgen regulated processing of the oncomir miR 27a which targets Prohibitin in prostate cancer; Increasing miR-27a expression results in reduced PHB mRNA and protein levels and increased expression of AR target genes and prostate cancer cell growth
130 hsa-miR-27a-3p PIP4K2B -0.37 0.00876 0.58 0 mirMAP -0.11 6.0E-5 NA
131 hsa-miR-27a-3p PITPNM2 -0.37 0.00876 0.25 0.07997 miRNATAP -0.17 0.00051 NA
132 hsa-miR-27a-3p PJA2 -0.37 0.00876 -0.55 0 miRNAWalker2 validate -0.11 0.00103 NA
133 hsa-miR-27a-3p PPARA -0.37 0.00876 -0.61 3.0E-5 MirTarget; miRNATAP -0.4 0 NA
134 hsa-miR-27a-3p PPARG -0.37 0.00876 0.33 0.04066 MirTarget; miRNATAP -0.28 0 NA
135 hsa-miR-27a-3p PPP3R1 -0.37 0.00876 -0.35 0 miRNATAP -0.12 0 NA
136 hsa-miR-27a-3p PTAR1 -0.37 0.00876 -0.3 0.00286 MirTarget -0.13 0.00027 NA
137 hsa-miR-27a-3p RAP2C -0.37 0.00876 -0.41 9.0E-5 miRNATAP -0.16 1.0E-5 NA
138 hsa-miR-27a-3p RGPD5 -0.37 0.00876 -0.38 0.20276 MirTarget -0.27 0.00996 NA
139 hsa-miR-27a-3p RMND5A -0.37 0.00876 -0.49 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.27 0 NA
140 hsa-miR-27a-3p RORA -0.37 0.00876 -1.19 0 mirMAP; miRNATAP -0.3 0 NA
141 hsa-miR-27a-3p RPL19 -0.37 0.00876 0.34 0.00137 miRNAWalker2 validate -0.1 0.00514 NA
142 hsa-miR-27a-3p RPS18 -0.37 0.00876 0.5 5.0E-5 miRNAWalker2 validate -0.15 0.00049 NA
143 hsa-miR-27a-3p RPS24 -0.37 0.00876 0.27 0.0468 miRNAWalker2 validate -0.1 0.02967 NA
144 hsa-miR-27a-3p RPS6KB1 -0.37 0.00876 0.04 0.57907 MirTarget; miRNATAP -0.14 0 NA
145 hsa-miR-27a-3p RPTOR -0.37 0.00876 0.68 0 miRNAWalker2 validate -0.13 1.0E-5 NA
146 hsa-miR-27a-3p RREB1 -0.37 0.00876 -0.27 0.09406 miRNATAP -0.17 0.00186 NA
147 hsa-miR-27a-3p RYBP -0.37 0.00876 -0.69 0 MirTarget -0.15 0 NA
148 hsa-miR-27a-3p SAP30BP -0.37 0.00876 0.37 0 miRNATAP -0.1 0.00027 NA
149 hsa-miR-27a-3p SATB2 -0.37 0.00876 0.52 0.00119 MirTarget; miRNATAP -0.14 0.00952 NA
150 hsa-miR-27a-3p SBF2 -0.37 0.00876 -0.14 0.24837 MirTarget -0.12 0.00761 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 47 1805 6.326e-09 2.943e-05
2 STEROID HORMONE MEDIATED SIGNALING PATHWAY 11 125 9.909e-08 0.0002305
3 POSITIVE REGULATION OF GENE EXPRESSION 42 1733 3.491e-07 0.0005412
4 RESPONSE TO ENDOGENOUS STIMULUS 37 1450 5.816e-07 0.0005412
5 CELLULAR RESPONSE TO HORMONE STIMULUS 21 552 5.032e-07 0.0005412
6 HORMONE MEDIATED SIGNALING PATHWAY 11 158 1.058e-06 0.0008202
7 RESPONSE TO INSULIN 12 205 2.139e-06 0.001244
8 INTRACELLULAR RECEPTOR SIGNALING PATHWAY 11 168 1.935e-06 0.001244
9 CELLULAR RESPONSE TO INSULIN STIMULUS 10 146 3.818e-06 0.001882
10 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 12 218 4.044e-06 0.001882
11 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 22 724 1.036e-05 0.004383
12 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 22 740 1.454e-05 0.005636
13 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 26 1008 2.794e-05 0.009286
14 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 38 1784 2.772e-05 0.009286
15 RESPONSE TO HORMONE 24 893 3.033e-05 0.009409
NumGOOverlapSizeP ValueAdj. P Value
1 STEROID HORMONE RECEPTOR ACTIVITY 7 59 3.003e-06 0.00279
2 ENZYME BINDING 39 1737 6.323e-06 0.002937
3 TRANSCRIPTION FACTOR ACTIVITY DIRECT LIGAND REGULATED SEQUENCE SPECIFIC DNA BINDING 6 48 1.149e-05 0.003559
NumGOOverlapSizeP ValueAdj. P Value
1 NUCLEAR OUTER MEMBRANE ENDOPLASMIC RETICULUM MEMBRANE NETWORK 27 1005 9.371e-06 0.005473

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 AMPK_signaling_pathway_hsa04152 9 121 5.999e-06 0.0003119
2 FoxO_signaling_pathway_hsa04068 8 132 8.631e-05 0.002244
3 mTOR_signaling_pathway_hsa04150 8 151 0.0002191 0.003797
4 Autophagy_animal_hsa04140 5 128 0.01203 0.1564
5 Phosphatidylinositol_signaling_system_hsa04070 4 99 0.02147 0.2233
6 Cellular_senescence_hsa04218 5 160 0.02851 0.2269
7 cGMP_PKG_signaling_pathway_hsa04022 5 163 0.03054 0.2269
8 MAPK_signaling_pathway_hsa04010 7 295 0.03908 0.254
9 Rap1_signaling_pathway_hsa04015 5 206 0.06979 0.3356
10 Phospholipase_D_signaling_pathway_hsa04072 4 146 0.07099 0.3356
11 Wnt_signaling_pathway_hsa04310 4 146 0.07099 0.3356
12 VEGF_signaling_pathway_hsa04370 2 59 0.1305 0.4374
13 Sphingolipid_signaling_pathway_hsa04071 3 118 0.1316 0.4374
14 Cell_cycle_hsa04110 3 124 0.1463 0.4374
15 Oocyte_meiosis_hsa04114 3 124 0.1463 0.4374
16 cAMP_signaling_pathway_hsa04024 4 198 0.1612 0.4374
17 p53_signaling_pathway_hsa04115 2 68 0.1636 0.4374
18 PI3K_Akt_signaling_pathway_hsa04151 6 352 0.1743 0.4374
19 Adherens_junction_hsa04520 2 72 0.1787 0.4374
20 Apelin_signaling_pathway_hsa04371 3 137 0.1798 0.4374
21 Regulation_of_actin_cytoskeleton_hsa04810 4 208 0.182 0.4374
22 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 3 139 0.1851 0.4374
23 Cell_adhesion_molecules_.CAMs._hsa04514 3 145 0.2013 0.4551
24 TGF_beta_signaling_pathway_hsa04350 2 84 0.2252 0.4767
25 ErbB_signaling_pathway_hsa04012 2 85 0.2292 0.4767
26 Endocytosis_hsa04144 4 244 0.2627 0.5253
27 HIF_1_signaling_pathway_hsa04066 2 100 0.2883 0.5391
28 TNF_signaling_pathway_hsa04668 2 108 0.3197 0.5733
29 Focal_adhesion_hsa04510 3 199 0.3559 0.6169
30 Ras_signaling_pathway_hsa04014 3 232 0.45 0.6883
31 Tight_junction_hsa04530 2 170 0.5426 0.8061
32 Calcium_signaling_pathway_hsa04020 2 182 0.5796 0.8372

Quest ID: c84b78bb53320a82b3b2c58017d52215