Visible node/edge number:
Node colors:
Node labels:

show label of nodes with degree >=

Node sizes:
Edge colors:
Edge widths factor:
Layout:

gravity >=

edgeLength =

GRN in network:

Notice: IE browser need to manually refresh (F5) this page after resetting the network.

This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-361-5p ABCA1 0.97 0 -0.71 0.00276 miRanda; mirMAP -0.32 0 NA
2 hsa-miR-361-5p ABCA8 0.97 0 -5.33 0 miRanda -0.7 0.00034 NA
3 hsa-miR-361-5p ABCD2 0.97 0 -3.08 0 miRanda -1.28 0 NA
4 hsa-miR-361-5p ABL1 0.97 0 -1.32 0 miRanda -0.32 0 NA
5 hsa-miR-361-5p ABL2 0.97 0 -0.32 0.04554 mirMAP -0.15 0.00146 NA
6 hsa-miR-361-5p ACACB 0.97 0 -2.93 0 miRanda -0.48 0 NA
7 hsa-miR-361-5p ACTC1 0.97 0 -7.19 0 miRanda; miRNATAP -3.21 0 NA
8 hsa-miR-361-5p ACTN4 0.97 0 -0.06 0.65476 miRanda -0.18 1.0E-5 NA
9 hsa-miR-361-5p ADAM12 0.97 0 0.88 0.05623 miRanda -0.82 0 NA
10 hsa-miR-361-5p ADAM19 0.97 0 -1.06 0.01895 miRanda -1.17 0 NA
11 hsa-miR-361-5p ADAM28 0.97 0 -0.73 0.15943 mirMAP -0.49 0.00113 NA
12 hsa-miR-361-5p ADAMTS5 0.97 0 -2.16 0 PITA; miRanda -0.64 0 NA
13 hsa-miR-361-5p ADCY2 0.97 0 -3.87 0 MirTarget; PITA; miRanda; miRNATAP -1.04 0 NA
14 hsa-miR-361-5p ADCY9 0.97 0 -1.5 0 miRanda -0.65 0 NA
15 hsa-miR-361-5p ADCYAP1 0.97 0 -3.51 0 miRanda -0.98 0 NA
16 hsa-miR-361-5p ADORA1 0.97 0 0.39 0.31104 miRanda -0.57 0 NA
17 hsa-miR-361-5p ADRA2A 0.97 0 -2.58 0 miRanda -0.88 0 NA
18 hsa-miR-361-5p AFF4 0.97 0 -0.82 0 miRanda -0.1 0.02408 NA
19 hsa-miR-361-5p AGPS 0.97 0 -0.1 0.48101 miRanda; miRNATAP -0.13 0.00105 NA
20 hsa-miR-361-5p AHNAK 0.97 0 -1.66 0 miRanda -0.55 0 NA
21 hsa-miR-361-5p AIDA 0.97 0 -0.31 0.01307 miRanda -0.22 0 NA
22 hsa-miR-361-5p AJAP1 0.97 0 -1.65 0.0004 miRanda -0.38 0.0057 NA
23 hsa-miR-361-5p AKAP11 0.97 0 -0.8 0 mirMAP -0.16 0.00083 NA
24 hsa-miR-361-5p AKAP12 0.97 0 -2.95 0 miRanda -0.63 0 NA
25 hsa-miR-361-5p AKAP5 0.97 0 0.05 0.84509 miRanda -0.19 0.02017 NA
26 hsa-miR-361-5p AKAP6 0.97 0 -3.34 0 miRanda -1.09 0 NA
27 hsa-miR-361-5p AKR1B10 0.97 0 -3.05 0.00095 miRanda -0.69 0.01017 NA
28 hsa-miR-361-5p ALDH1L2 0.97 0 -1.12 0.02448 miRanda; mirMAP; miRNATAP -1.11 0 NA
29 hsa-miR-361-5p ANGPT1 0.97 0 -2 1.0E-5 miRanda -0.48 0.00023 NA
30 hsa-miR-361-5p ANGPTL2 0.97 0 -1.73 0 miRanda -1.12 0 NA
31 hsa-miR-361-5p ANKRD44 0.97 0 -1.93 0 miRanda -0.64 0 NA
32 hsa-miR-361-5p ANO1 0.97 0 1.02 0.02235 miRanda; miRNATAP -0.27 0.0388 NA
33 hsa-miR-361-5p ANO6 0.97 0 -0.74 3.0E-5 MirTarget; miRanda -0.15 0.00429 NA
34 hsa-miR-361-5p AOC3 0.97 0 -3.69 0 MirTarget; miRanda -1.22 0 NA
35 hsa-miR-361-5p AP1S2 0.97 0 -1.31 0 miRanda -0.54 0 NA
36 hsa-miR-361-5p AP3S1 0.97 0 -0.06 0.68914 miRanda -0.15 0.0004 NA
37 hsa-miR-361-5p AP4S1 0.97 0 -0.6 0.00055 miRanda -0.21 3.0E-5 NA
38 hsa-miR-361-5p APBB2 0.97 0 -0.59 0.0014 miRanda -0.34 0 NA
39 hsa-miR-361-5p APOLD1 0.97 0 -2.62 0 miRanda -0.47 0 NA
40 hsa-miR-361-5p AQP9 0.97 0 0.86 0.13122 miRanda -1.04 0 NA
41 hsa-miR-361-5p ARF4 0.97 0 0.06 0.68077 miRNAWalker2 validate; miRanda -0.12 0.00153 NA
42 hsa-miR-361-5p ARFGAP3 0.97 0 -0.25 0.10361 miRanda -0.22 0 NA
43 hsa-miR-361-5p ARHGAP15 0.97 0 -1.33 0.00101 miRanda -0.79 0 NA
44 hsa-miR-361-5p ARHGAP20 0.97 0 -3.52 0 miRanda -1.28 0 NA
45 hsa-miR-361-5p ARHGAP21 0.97 0 -0.23 0.20424 miRanda -0.12 0.0273 NA
46 hsa-miR-361-5p ARHGAP31 0.97 0 -1.16 2.0E-5 mirMAP -0.6 0 NA
47 hsa-miR-361-5p ARHGAP6 0.97 0 -3.25 0 PITA; miRanda -0.36 0.0112 NA
48 hsa-miR-361-5p ARHGAP9 0.97 0 -0.84 0.05605 miRanda -0.92 0 NA
49 hsa-miR-361-5p ARHGEF37 0.97 0 -1.85 0 miRanda; miRNATAP -0.68 0 NA
50 hsa-miR-361-5p ARHGEF6 0.97 0 -1.32 0 miRanda -0.26 0.0017 NA
51 hsa-miR-361-5p ARL10 0.97 0 -1.12 0.00198 mirMAP -0.31 0.00375 NA
52 hsa-miR-361-5p ARL4C 0.97 0 -0.28 0.33535 miRanda -0.52 0 NA
53 hsa-miR-361-5p ARMC4 0.97 0 -3.15 0 miRNATAP -0.92 0 NA
54 hsa-miR-361-5p ARNTL 0.97 0 -0.36 0.08956 miRanda -0.27 1.0E-5 NA
55 hsa-miR-361-5p ARRB1 0.97 0 -1.05 0.00043 MirTarget; miRanda -0.2 0.02241 NA
56 hsa-miR-361-5p ARRDC3 0.97 0 -0.71 0.00062 MirTarget; PITA; miRanda; miRNATAP -0.23 9.0E-5 NA
57 hsa-miR-361-5p ARSB 0.97 0 -0.58 0.00052 miRanda -0.37 0 NA
58 hsa-miR-361-5p ART3 0.97 0 -1.79 0.00034 miRanda -0.72 0 NA
59 hsa-miR-361-5p ASXL3 0.97 0 -3.34 0 mirMAP -0.51 0.00129 NA
60 hsa-miR-361-5p ATAD1 0.97 0 -0.13 0.38155 miRanda -0.12 0.00433 NA
61 hsa-miR-361-5p ATF3 0.97 0 -3.23 0 miRanda -0.69 0 NA
62 hsa-miR-361-5p ATF7 0.97 0 -0.44 0.0002 mirMAP -0.13 0.00017 NA
63 hsa-miR-361-5p ATL3 0.97 0 -0.19 0.4343 mirMAP -0.25 0.0003 NA
64 hsa-miR-361-5p ATP8B4 0.97 0 -1.9 0 miRanda -0.93 0 NA
65 hsa-miR-361-5p AXL 0.97 0 -1.77 0 miRanda -1.02 0 NA
66 hsa-miR-361-5p B2M 0.97 0 -0 0.98848 miRanda -0.42 0 NA
67 hsa-miR-361-5p BACH1 0.97 0 -0.27 0.16316 miRanda; mirMAP -0.2 0.00029 NA
68 hsa-miR-361-5p BASP1 0.97 0 -0.12 0.79725 miRanda -0.26 0.04722 NA
69 hsa-miR-361-5p BBX 0.97 0 -0.51 0.00131 PITA; miRanda; mirMAP -0.12 0.00704 NA
70 hsa-miR-361-5p BCO2 0.97 0 -2.28 0 miRanda -0.31 0.00644 NA
71 hsa-miR-361-5p BDNF 0.97 0 -2.91 0 PITA; miRanda; miRNATAP -0.55 2.0E-5 NA
72 hsa-miR-361-5p BEND4 0.97 0 -1.97 7.0E-5 mirMAP -0.37 0.01166 NA
73 hsa-miR-361-5p BEND6 0.97 0 -0.8 0.03128 miRanda -0.46 2.0E-5 NA
74 hsa-miR-361-5p BIRC7 0.97 0 0.81 0.12357 miRanda -0.76 0 NA
75 hsa-miR-361-5p BMP2K 0.97 0 -0.34 0.13703 miRanda -0.18 0.00655 NA
76 hsa-miR-361-5p BMPR2 0.97 0 -0.59 4.0E-5 MirTarget; miRanda; mirMAP; miRNATAP -0.24 0 NA
77 hsa-miR-361-5p BRMS1L 0.97 0 -0.51 0.00391 miRanda -0.14 0.00562 NA
78 hsa-miR-361-5p BTG1 0.97 0 -0.8 2.0E-5 miRanda -0.23 2.0E-5 NA
79 hsa-miR-361-5p BTLA 0.97 0 -1.31 0.00559 miRanda -0.91 0 NA
80 hsa-miR-361-5p C1orf21 0.97 0 -1.51 0 mirMAP -0.16 0.02113 NA
81 hsa-miR-361-5p C2CD4A 0.97 0 0.55 0.29831 miRanda -0.37 0.01668 NA
82 hsa-miR-361-5p C4BPB 0.97 0 -0.9 0.15563 miRanda -0.38 0.03846 NA
83 hsa-miR-361-5p CACNB2 0.97 0 -2.97 0 miRanda -0.74 0 NA
84 hsa-miR-361-5p CACNB4 0.97 0 -2.87 0 miRanda; mirMAP -0.67 0 NA
85 hsa-miR-361-5p CALCOCO1 0.97 0 -1.07 0 miRanda -0.14 0.00122 NA
86 hsa-miR-361-5p CALCOCO2 0.97 0 -0.5 1.0E-5 miRNAWalker2 validate; miRanda -0.17 0 NA
87 hsa-miR-361-5p CALCRL 0.97 0 -0.67 0.01537 MirTarget; PITA; miRanda; miRNATAP -0.44 0 NA
88 hsa-miR-361-5p CALD1 0.97 0 -2.47 0 miRanda; miRNATAP -1.21 0 NA
89 hsa-miR-361-5p CALHM2 0.97 0 -0.53 0.01372 miRanda -0.24 0.0001 NA
90 hsa-miR-361-5p CAPN6 0.97 0 -3.48 0 PITA; miRanda; miRNATAP -0.55 0.00774 NA
91 hsa-miR-361-5p CASP1 0.97 0 -0.39 0.33513 miRanda -0.55 0 NA
92 hsa-miR-361-5p CASP4 0.97 0 0.1 0.69047 miRanda -0.25 0.00033 NA
93 hsa-miR-361-5p CAV1 0.97 0 -2.02 0 miRanda -1 0 NA
94 hsa-miR-361-5p CAV2 0.97 0 -0.86 0.01061 miRanda -0.63 0 NA
95 hsa-miR-361-5p CBLN1 0.97 0 -3.04 0 miRanda -0.69 2.0E-5 NA
96 hsa-miR-361-5p CBX6 0.97 0 -1.54 0 mirMAP -0.19 0.03211 NA
97 hsa-miR-361-5p CCDC152 0.97 0 -1.86 0 miRanda -0.44 0.00014 NA
98 hsa-miR-361-5p CCDC6 0.97 0 -0.27 0.05122 miRanda -0.24 0 NA
99 hsa-miR-361-5p CCDC88A 0.97 0 -0.76 0.01199 miRanda -0.35 6.0E-5 NA
100 hsa-miR-361-5p CCDC88B 0.97 0 0.26 0.37339 miRanda -0.19 0.0307 NA
101 hsa-miR-361-5p CCDC91 0.97 0 -0.41 0.01203 miRanda -0.16 0.00078 NA
102 hsa-miR-361-5p CCNYL1 0.97 0 -0.16 0.40711 MirTarget; miRanda; miRNATAP -0.16 0.00312 NA
103 hsa-miR-361-5p CCR6 0.97 0 -1.12 0.00057 miRanda -0.48 0 NA
104 hsa-miR-361-5p CD109 0.97 0 -0.51 0.31559 miRanda -0.95 0 NA
105 hsa-miR-361-5p CD177 0.97 0 -0.07 0.91649 miRanda; miRNATAP -0.73 6.0E-5 NA
106 hsa-miR-361-5p CD36 0.97 0 -1.94 0.00141 miRanda -0.56 0.00146 NA
107 hsa-miR-361-5p CD40 0.97 0 -0.38 0.28617 miRanda -0.33 0.00151 NA
108 hsa-miR-361-5p CD48 0.97 0 -1.58 0.00055 miRanda -0.98 0 NA
109 hsa-miR-361-5p CD84 0.97 0 -0.53 0.27947 mirMAP -1.08 0 NA
110 hsa-miR-361-5p CDADC1 0.97 0 -0.5 0.00184 miRanda -0.15 0.00124 NA
111 hsa-miR-361-5p CDC42BPA 0.97 0 -1.41 0 miRanda -0.36 0 NA
112 hsa-miR-361-5p CDH2 0.97 0 -0.37 0.51007 miRanda -0.9 0 NA
113 hsa-miR-361-5p CDK17 0.97 0 -0.52 0.00027 miRanda -0.15 0.00039 NA
114 hsa-miR-361-5p CEACAM21 0.97 0 -0.15 0.72613 miRanda -0.84 0 NA
115 hsa-miR-361-5p CELF2 0.97 0 -3.05 0 miRNATAP -1.27 0 NA
116 hsa-miR-361-5p CFL2 0.97 0 -2.62 0 miRanda -0.81 0 NA
117 hsa-miR-361-5p CGRRF1 0.97 0 -0.82 0 miRanda -0.1 0.005 NA
118 hsa-miR-361-5p CH25H 0.97 0 -3 0 miRanda -1.01 0 NA
119 hsa-miR-361-5p CHD9 0.97 0 -0.8 1.0E-5 PITA; miRanda -0.13 0.01508 NA
120 hsa-miR-361-5p CHST11 0.97 0 0.54 0.2311 miRanda -0.85 0 NA
121 hsa-miR-361-5p CISD1 0.97 0 -0.39 0.01804 miRNATAP -0.36 0 NA
122 hsa-miR-361-5p CISH 0.97 0 0.07 0.77166 miRanda -0.19 0.00414 NA
123 hsa-miR-361-5p CLDN11 0.97 0 -2.16 0 miRanda -0.33 0.01695 NA
124 hsa-miR-361-5p CLEC1A 0.97 0 -1.37 0 miRanda -0.53 0 NA
125 hsa-miR-361-5p CLEC3A 0.97 0 -5.97 0 miRanda -1.71 0 NA
126 hsa-miR-361-5p CLEC4E 0.97 0 -1.11 0.05437 miRanda -1.33 0 NA
127 hsa-miR-361-5p CLEC4GP1 0.97 0 -1.23 0.02196 miRanda -0.64 4.0E-5 NA
128 hsa-miR-361-5p CLEC7A 0.97 0 0.76 0.08786 miRanda -0.62 0 NA
129 hsa-miR-361-5p CLIC2 0.97 0 -1.44 0 PITA; miRanda; miRNATAP -0.53 0 NA
130 hsa-miR-361-5p CLIC4 0.97 0 -1.72 0 miRanda -0.82 0 NA
131 hsa-miR-361-5p CLIP4 0.97 0 -1.61 0 miRanda -0.63 0 NA
132 hsa-miR-361-5p CLN5 0.97 0 -0.32 0.02528 miRanda -0.15 0.00042 NA
133 hsa-miR-361-5p CLU 0.97 0 -2.85 0 miRanda -0.95 0 NA
134 hsa-miR-361-5p CMPK2 0.97 0 1.23 0.00022 miRanda -0.19 0.04534 NA
135 hsa-miR-361-5p CNRIP1 0.97 0 -2.41 0 miRanda -0.83 0 NA
136 hsa-miR-361-5p CNTLN 0.97 0 -1.17 0.00322 miRanda -0.42 0.00031 NA
137 hsa-miR-361-5p COBL 0.97 0 -2.83 2.0E-5 miRanda -0.44 0.02337 NA
138 hsa-miR-361-5p COL11A1 0.97 0 4.69 0 miRanda; miRNATAP -0.97 7.0E-5 NA
139 hsa-miR-361-5p COL14A1 0.97 0 -3.66 0 miRanda -1.07 0 NA
140 hsa-miR-361-5p COL15A1 0.97 0 -0.94 0.00988 miRanda -0.9 0 NA
141 hsa-miR-361-5p COL4A4 0.97 0 -2.67 0 MirTarget; miRanda -0.6 1.0E-5 NA
142 hsa-miR-361-5p CORIN 0.97 0 -0.97 0.01159 miRanda -0.41 0.00027 NA
143 hsa-miR-361-5p CORO1C 0.97 0 -1.12 0 miRanda -0.49 0 NA
144 hsa-miR-361-5p CPT1A 0.97 0 -0.83 0.00093 miRanda -0.25 0.00051 NA
145 hsa-miR-361-5p CR1 0.97 0 -1.99 0.00029 MirTarget; miRanda -1.22 0 NA
146 hsa-miR-361-5p CREB3L2 0.97 0 -0.29 0.1662 miRanda -0.16 0.01127 NA
147 hsa-miR-361-5p CREB5 0.97 0 -2.28 0 PITA; miRNATAP -0.75 0 NA
148 hsa-miR-361-5p CREG1 0.97 0 -0.22 0.23382 MirTarget; miRanda -0.15 0.00691 NA
149 hsa-miR-361-5p CSF2RA 0.97 0 -0.46 0.33646 miRanda -0.99 0 NA
150 hsa-miR-361-5p CSF3R 0.97 0 -0.24 0.56343 miRanda -0.59 0 NA
NumGOOverlapSizeP ValueAdj. P Value
1 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 153 1848 9.425e-21 4.386e-17
2 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 125 1395 1.193e-19 2.775e-16
3 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 136 1656 4.415e-18 5.135e-15
4 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 137 1672 3.934e-18 5.135e-15
5 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 85 799 7.279e-18 6.358e-15
6 RESPONSE TO OXYGEN CONTAINING COMPOUND 120 1381 8.198e-18 6.358e-15
7 REGULATION OF CELL DIFFERENTIATION 125 1492 2.745e-17 1.825e-14
8 POSITIVE REGULATION OF CELL COMMUNICATION 123 1532 1.333e-15 7.756e-13
9 RESPONSE TO ENDOGENOUS STIMULUS 118 1450 2.126e-15 1.099e-12
10 POSITIVE REGULATION OF RESPONSE TO STIMULUS 142 1929 7.476e-15 3.479e-12
11 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 99 1142 1.082e-14 4.577e-12
12 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 111 1360 1.364e-14 4.882e-12
13 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 91 1008 1.353e-14 4.882e-12
14 REGULATION OF CELLULAR COMPONENT MOVEMENT 76 771 2.811e-14 9.342e-12
15 NEUROGENESIS 112 1402 4.382e-14 1.359e-11
16 REGULATION OF CELL DEVELOPMENT 79 836 8.102e-14 2.356e-11
17 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 87 983 1.688e-13 4.619e-11
18 RESPONSE TO WOUNDING 61 563 1.953e-13 5.021e-11
19 CELL MOTILITY 78 835 2.158e-13 5.021e-11
20 LOCALIZATION OF CELL 78 835 2.158e-13 5.021e-11
21 BLOOD VESSEL MORPHOGENESIS 47 364 2.442e-13 5.412e-11
22 LOCOMOTION 94 1114 2.751e-13 5.819e-11
23 VASCULATURE DEVELOPMENT 54 469 4.464e-13 9.03e-11
24 CARDIOVASCULAR SYSTEM DEVELOPMENT 74 788 7.219e-13 1.344e-10
25 CIRCULATORY SYSTEM DEVELOPMENT 74 788 7.219e-13 1.344e-10
26 INTRACELLULAR SIGNAL TRANSDUCTION 117 1572 1.372e-12 2.455e-10
27 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 101 1275 1.556e-12 2.681e-10
28 WOUND HEALING 53 470 1.685e-12 2.799e-10
29 POSITIVE REGULATION OF MOLECULAR FUNCTION 128 1791 1.767e-12 2.835e-10
30 REGULATION OF PHOSPHORUS METABOLIC PROCESS 119 1618 1.89e-12 2.931e-10
31 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 67 689 1.963e-12 2.946e-10
32 NEGATIVE REGULATION OF CELL COMMUNICATION 96 1192 2.316e-12 3.368e-10
33 REGULATION OF CELL PROLIFERATION 112 1496 3.102e-12 4.373e-10
34 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 77 876 6.656e-12 9.109e-10
35 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 86 1036 7.591e-12 9.811e-10
36 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 86 1036 7.591e-12 9.811e-10
37 CELL DEVELOPMENT 107 1426 8.955e-12 1.126e-09
38 ANGIOGENESIS 39 293 1.074e-11 1.315e-09
39 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 41 321 1.203e-11 1.435e-09
40 REGULATION OF PROTEIN MODIFICATION PROCESS 121 1710 1.561e-11 1.815e-09
41 REGULATION OF MAPK CASCADE 63 660 2.06e-11 2.338e-09
42 RESPONSE TO LIPID 76 888 3.329e-11 3.688e-09
43 TISSUE DEVELOPMENT 110 1518 3.728e-11 4.034e-09
44 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 83 1021 5.258e-11 5.56e-09
45 POSITIVE REGULATION OF MAPK CASCADE 50 470 6.117e-11 6.325e-09
46 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 89 1135 6.61e-11 6.686e-09
47 CELLULAR RESPONSE TO LIPID 49 457 7.252e-11 7.18e-09
48 POSITIVE REGULATION OF CELL DIFFERENTIATION 71 823 1.088e-10 1.055e-08
49 RESPONSE TO NITROGEN COMPOUND 73 859 1.158e-10 1.1e-08
50 REGULATION OF ION TRANSPORT 57 592 1.398e-10 1.301e-08
51 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 51 498 1.55e-10 1.414e-08
52 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 69 801 2.164e-10 1.936e-08
53 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 66 750 2.249e-10 1.974e-08
54 REGULATION OF TRANSPORT 122 1804 2.33e-10 2.007e-08
55 REGULATION OF METAL ION TRANSPORT 39 325 2.522e-10 2.133e-08
56 HOMEOSTATIC PROCESS 98 1337 2.752e-10 2.287e-08
57 CELLULAR RESPONSE TO BIOTIC STIMULUS 26 163 6.081e-10 4.964e-08
58 CIRCULATORY SYSTEM PROCESS 41 366 7.199e-10 5.775e-08
59 CELLULAR RESPONSE TO NITROGEN COMPOUND 50 505 7.607e-10 5.999e-08
60 REGULATION OF NEURON DIFFERENTIATION 53 554 7.988e-10 6.195e-08
61 RESPONSE TO GROWTH FACTOR 48 475 8.519e-10 6.498e-08
62 REGULATION OF NEURON PROJECTION DEVELOPMENT 43 408 1.838e-09 1.38e-07
63 BIOLOGICAL ADHESION 79 1032 2.597e-09 1.918e-07
64 REGULATION OF CELL PROJECTION ORGANIZATION 52 558 2.881e-09 2.095e-07
65 POSITIVE REGULATION OF CATALYTIC ACTIVITY 104 1518 3.099e-09 2.218e-07
66 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 85 1152 3.532e-09 2.476e-07
67 NEURON DIFFERENTIATION 70 874 3.566e-09 2.476e-07
68 REGULATION OF EPITHELIAL CELL PROLIFERATION 34 285 4.171e-09 2.854e-07
69 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 102 1492 5.032e-09 3.345e-07
70 POSITIVE REGULATION OF TRANSPORT 73 936 5.013e-09 3.345e-07
71 REGULATION OF KINASE ACTIVITY 64 776 5.652e-09 3.704e-07
72 POSITIVE REGULATION OF CELL DEVELOPMENT 46 472 6.065e-09 3.919e-07
73 POSITIVE REGULATION OF CELL PROLIFERATION 66 814 6.338e-09 4.04e-07
74 NEGATIVE REGULATION OF CELL DIFFERENTIATION 54 609 8.104e-09 5.095e-07
75 CHEMICAL HOMEOSTASIS 69 874 8.336e-09 5.172e-07
76 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 37 337 8.462e-09 5.181e-07
77 RESPONSE TO BACTERIUM 49 528 9.548e-09 5.77e-07
78 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 43 437 1.443e-08 8.608e-07
79 PROTEIN PHOSPHORYLATION 72 944 1.617e-08 9.523e-07
80 REGULATION OF RESPONSE TO STRESS 99 1468 1.739e-08 1.011e-06
81 REGULATION OF CELL DEATH 99 1472 1.992e-08 1.144e-06
82 RESPONSE TO EXTERNAL STIMULUS 116 1821 2.165e-08 1.228e-06
83 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 123 1977 2.912e-08 1.613e-06
84 REGULATION OF IMMUNE SYSTEM PROCESS 95 1403 2.892e-08 1.613e-06
85 POSITIVE REGULATION OF KINASE ACTIVITY 45 482 3.249e-08 1.779e-06
86 IMMUNE SYSTEM PROCESS 123 1984 3.559e-08 1.925e-06
87 POSITIVE REGULATION OF LOCOMOTION 41 420 3.92e-08 2.097e-06
88 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 42 437 4.162e-08 2.201e-06
89 REGULATION OF TRANSMEMBRANE TRANSPORT 41 426 5.811e-08 3.038e-06
90 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 71 957 6.154e-08 3.181e-06
91 REGULATION OF RESPONSE TO WOUNDING 40 413 7.119e-08 3.64e-06
92 POSITIVE REGULATION OF NEURON DIFFERENTIATION 33 306 8.31e-08 4.203e-06
93 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 112 1784 8.515e-08 4.26e-06
94 CONNECTIVE TISSUE DEVELOPMENT 25 194 1.054e-07 5.216e-06
95 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 26 208 1.092e-07 5.349e-06
96 SKELETAL SYSTEM DEVELOPMENT 42 455 1.284e-07 6.224e-06
97 CYCLIC NUCLEOTIDE METABOLIC PROCESS 13 57 1.698e-07 8.144e-06
98 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 68 926 1.745e-07 8.286e-06
99 NEURON DEVELOPMENT 55 687 1.854e-07 8.638e-06
100 REGULATION OF ORGAN MORPHOGENESIS 28 242 1.856e-07 8.638e-06
101 CARTILAGE DEVELOPMENT 21 147 1.901e-07 8.759e-06
102 CELL CELL SIGNALING 59 767 2.566e-07 1.159e-05
103 REGULATION OF CELL MORPHOGENESIS 47 552 2.558e-07 1.159e-05
104 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 27 232 2.724e-07 1.219e-05
105 RESPONSE TO CYTOKINE 56 714 2.799e-07 1.24e-05
106 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 20 138 2.921e-07 1.282e-05
107 NEGATIVE REGULATION OF IMMUNE EFFECTOR PROCESS 17 102 2.964e-07 1.289e-05
108 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 42 470 3.107e-07 1.338e-05
109 RESPONSE TO PEPTIDE 38 404 3.188e-07 1.361e-05
110 CHONDROCYTE DIFFERENTIATION 13 60 3.224e-07 1.364e-05
111 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 36 372 3.276e-07 1.373e-05
112 POSITIVE REGULATION OF HYDROLASE ACTIVITY 66 905 3.429e-07 1.412e-05
113 RESPONSE TO BIOTIC STIMULUS 65 886 3.425e-07 1.412e-05
114 REGULATION OF SYSTEM PROCESS 44 507 3.672e-07 1.499e-05
115 HEMOSTASIS 32 311 3.801e-07 1.538e-05
116 POSITIVE REGULATION OF ION TRANSPORT 27 236 3.846e-07 1.543e-05
117 POSITIVE REGULATION OF GENE EXPRESSION 107 1733 3.929e-07 1.562e-05
118 REGULATION OF CYTOKINE PRODUCTION 47 563 4.522e-07 1.783e-05
119 CELL PROLIFERATION 53 672 4.959e-07 1.939e-05
120 REGULATION OF TRANSPORTER ACTIVITY 24 198 5.92e-07 2.278e-05
121 DEVELOPMENTAL GROWTH 33 333 5.924e-07 2.278e-05
122 TUBE DEVELOPMENT 46 552 6.307e-07 2.406e-05
123 MUSCLE STRUCTURE DEVELOPMENT 39 432 6.362e-07 2.407e-05
124 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 31 303 6.528e-07 2.449e-05
125 REGULATION OF MAP KINASE ACTIVITY 32 319 6.697e-07 2.493e-05
126 EXTRACELLULAR STRUCTURE ORGANIZATION 31 304 7.011e-07 2.589e-05
127 REGULATION OF SECRETION 54 699 7.353e-07 2.694e-05
128 LEUKOCYTE MIGRATION 28 259 7.514e-07 2.732e-05
129 POSITIVE REGULATION OF CYTOKINE PRODUCTION 35 370 8.147e-07 2.939e-05
130 NEGATIVE REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 9 29 8.228e-07 2.945e-05
131 REGULATION OF BODY FLUID LEVELS 43 506 8.758e-07 3.064e-05
132 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 45 541 8.793e-07 3.064e-05
133 NEGATIVE REGULATION OF CELL DEATH 63 872 8.825e-07 3.064e-05
134 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 45 541 8.793e-07 3.064e-05
135 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 26 232 9.372e-07 3.23e-05
136 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 37 406 9.824e-07 3.361e-05
137 ACTIVATION OF PROTEIN KINASE ACTIVITY 29 279 1.08e-06 3.666e-05
138 LIPID LOCALIZATION 28 264 1.104e-06 3.723e-05
139 RESPONSE TO ORGANIC CYCLIC COMPOUND 65 917 1.135e-06 3.8e-05
140 GROWTH 37 410 1.243e-06 4.13e-05
141 POSITIVE REGULATION OF ENDOCYTOSIS 17 114 1.498e-06 4.943e-05
142 REGULATION OF TRANSFERASE ACTIVITY 66 946 1.617e-06 5.297e-05
143 PHOSPHORYLATION 80 1228 1.83e-06 5.926e-05
144 CENTRAL NERVOUS SYSTEM DEVELOPMENT 62 872 1.834e-06 5.926e-05
145 POSITIVE REGULATION OF PROTEIN SECRETION 24 211 1.873e-06 6.011e-05
146 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 17 116 1.918e-06 6.071e-05
147 REGULATION OF CELL ADHESION 49 629 1.913e-06 6.071e-05
148 NEGATIVE REGULATION OF CELL DEVELOPMENT 30 303 1.951e-06 6.135e-05
149 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 20 156 2.12e-06 6.621e-05
150 POSITIVE REGULATION OF SECRETION 34 370 2.239e-06 6.947e-05
151 REGULATION OF GROWTH 49 633 2.286e-06 7.044e-05
152 CELLULAR RESPONSE TO PEPTIDE 28 274 2.306e-06 7.044e-05
153 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 36 404 2.316e-06 7.044e-05
154 REGULATION OF LIPID STORAGE 10 41 2.358e-06 7.126e-05
155 REGULATION OF PROTEIN SECRETION 35 389 2.571e-06 7.718e-05
156 PEPTIDYL TYROSINE MODIFICATION 22 186 2.612e-06 7.791e-05
157 REGULATION OF CELLULAR COMPONENT BIOGENESIS 56 767 2.652e-06 7.861e-05
158 REGULATION OF ION HOMEOSTASIS 23 201 2.757e-06 8.118e-05
159 CELLULAR HOMEOSTASIS 51 676 2.977e-06 8.711e-05
160 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 42 513 3.046e-06 8.857e-05
161 REGULATION OF HYDROLASE ACTIVITY 84 1327 3.089e-06 8.929e-05
162 REGULATION OF BLOOD CIRCULATION 29 295 3.323e-06 9.545e-05
163 POSITIVE REGULATION OF CYTOKINE SECRETION 15 96 3.392e-06 9.682e-05
164 NEGATIVE REGULATION OF IMMUNE RESPONSE 17 121 3.471e-06 9.847e-05
165 BEHAVIOR 42 516 3.526e-06 9.944e-05
166 CELLULAR RESPONSE TO HORMONE STIMULUS 44 552 3.566e-06 9.995e-05
167 CAMP METABOLIC PROCESS 9 34 3.63e-06 0.0001012
168 DEFENSE RESPONSE 79 1231 3.75e-06 0.0001033
169 REGULATION OF HOMEOSTATIC PROCESS 38 447 3.751e-06 0.0001033
170 MUSCLE SYSTEM PROCESS 28 282 4.034e-06 0.0001104
171 REGULATION OF IMMUNE RESPONSE 60 858 4.555e-06 0.0001239
172 REGULATION OF PHOSPHOLIPASE ACTIVITY 12 64 4.621e-06 0.000125
173 SENSORY PERCEPTION OF PAIN 13 75 4.662e-06 0.000125
174 ION HOMEOSTASIS 45 576 4.676e-06 0.000125
175 REGULATION OF ERK1 AND ERK2 CASCADE 25 238 4.884e-06 0.0001299
176 POSITIVE REGULATION OF HEART GROWTH 8 27 5.038e-06 0.0001332
177 REGULATION OF CALCIUM ION TRANSPORT 23 209 5.347e-06 0.0001406
178 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 47 616 5.42e-06 0.0001417
179 NEURON PROJECTION DEVELOPMENT 43 545 5.948e-06 0.0001546
180 REGULATION OF SYNAPSE ORGANIZATION 16 113 6.038e-06 0.0001555
181 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 67 1004 6.051e-06 0.0001555
182 REGULATION OF DEVELOPMENTAL GROWTH 28 289 6.449e-06 0.0001635
183 REGULATION OF CARDIAC MUSCLE CONTRACTION 12 66 6.459e-06 0.0001635
184 REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 15 101 6.465e-06 0.0001635
185 NEGATIVE REGULATION OF TRANSPORT 38 458 6.605e-06 0.0001661
186 CYCLIC NUCLEOTIDE MEDIATED SIGNALING 10 46 7.216e-06 0.0001805
187 POSITIVE REGULATION OF CELL DEATH 46 605 7.467e-06 0.0001858
188 TISSUE MORPHOGENESIS 42 533 7.865e-06 0.0001947
189 REGULATION OF ENDOCYTOSIS 22 199 7.91e-06 0.0001947
190 BONE DEVELOPMENT 19 156 8.098e-06 0.0001973
191 REGULATION OF LEUKOCYTE MEDIATED IMMUNITY 19 156 8.098e-06 0.0001973
192 REGULATION OF MEMBRANE POTENTIAL 31 343 8.707e-06 0.000211
193 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 38 465 9.35e-06 0.0002231
194 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 15 104 9.324e-06 0.0002231
195 REGULATION OF INTERLEUKIN 6 PRODUCTION 15 104 9.324e-06 0.0002231
196 POSITIVE REGULATION OF ERK1 AND ERK2 CASCADE 20 172 9.54e-06 0.0002265
197 REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 14 92 9.804e-06 0.0002312
198 POSITIVE REGULATION OF ORGAN GROWTH 9 38 9.839e-06 0.0002312
199 CELL DEATH 66 1001 1.05e-05 0.0002443
200 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 24 233 1.049e-05 0.0002443
201 SYNAPSE ORGANIZATION 18 145 1.068e-05 0.0002462
202 REGULATION OF JNK CASCADE 19 159 1.069e-05 0.0002462
203 HEAD DEVELOPMENT 51 709 1.123e-05 0.0002574
204 RESPONSE TO ABIOTIC STIMULUS 67 1024 1.151e-05 0.0002625
205 SECOND MESSENGER MEDIATED SIGNALING 19 160 1.17e-05 0.0002656
206 NEGATIVE REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 7 22 1.181e-05 0.0002668
207 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 12 70 1.214e-05 0.0002729
208 MESENCHYME DEVELOPMENT 21 190 1.269e-05 0.0002838
209 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 104 1805 1.281e-05 0.0002853
210 REGULATION OF ANATOMICAL STRUCTURE SIZE 38 472 1.311e-05 0.0002893
211 GLOMERULUS DEVELOPMENT 10 49 1.312e-05 0.0002893
212 SYSTEM PROCESS 103 1785 1.333e-05 0.0002926
213 CELL CHEMOTAXIS 19 162 1.4e-05 0.0003043
214 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 19 162 1.4e-05 0.0003043
215 REGULATION OF CELLULAR LOCALIZATION 79 1277 1.42e-05 0.0003072
216 REGULATION OF LIPASE ACTIVITY 13 83 1.471e-05 0.000317
217 POSITIVE REGULATION OF GROWTH 24 238 1.499e-05 0.0003214
218 VASCULAR PROCESS IN CIRCULATORY SYSTEM 19 163 1.529e-05 0.0003263
219 RESPONSE TO HORMONE 60 893 1.537e-05 0.0003266
220 REGULATION OF OSSIFICATION 20 178 1.592e-05 0.0003366
221 MEMBRANE DEPOLARIZATION 11 61 1.697e-05 0.0003557
222 CELLULAR RESPONSE TO CYTOKINE STIMULUS 45 606 1.695e-05 0.0003557
223 RETINA VASCULATURE DEVELOPMENT IN CAMERA TYPE EYE 6 16 1.743e-05 0.0003638
224 IMMUNE RESPONSE 70 1100 1.823e-05 0.0003786
225 NEURON MIGRATION 15 110 1.859e-05 0.0003845
226 REGULATION OF EPITHELIAL CELL MIGRATION 19 166 1.983e-05 0.0004083
227 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 14 98 2.056e-05 0.0004214
228 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 21 197 2.203e-05 0.0004496
229 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 18 154 2.451e-05 0.0004958
230 AMEBOIDAL TYPE CELL MIGRATION 18 154 2.451e-05 0.0004958
231 REGULATION OF INFLAMMATORY RESPONSE 27 294 2.462e-05 0.0004958
232 REGULATION OF GTPASE ACTIVITY 48 673 2.529e-05 0.0005072
233 REGULATION OF CATABOLIC PROCESS 51 731 2.546e-05 0.0005084
234 CYCLIC NUCLEOTIDE CATABOLIC PROCESS 6 17 2.608e-05 0.0005163
235 NEGATIVE REGULATION OF LIPID STORAGE 6 17 2.608e-05 0.0005163
236 REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY 15 114 2.862e-05 0.0005643
237 MORPHOGENESIS OF AN EPITHELIUM 33 400 2.961e-05 0.0005813
238 MEMBRANE ASSEMBLY 7 25 3.013e-05 0.0005865
239 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL BY SARCOPLASMIC RETICULUM 7 25 3.013e-05 0.0005865
240 RHYTHMIC PROCESS 27 298 3.123e-05 0.0006055
241 SINGLE ORGANISM BEHAVIOR 32 384 3.203e-05 0.0006183
242 DEVELOPMENTAL CELL GROWTH 12 77 3.285e-05 0.0006317
243 PROTEIN LOCALIZATION 102 1805 3.454e-05 0.0006615
244 CELL ACTIVATION 42 568 3.557e-05 0.0006784
245 NEGATIVE REGULATION OF PHOSPHORYLATION 34 422 3.647e-05 0.0006927
246 CELLULAR COMPONENT MORPHOGENESIS 59 900 3.684e-05 0.0006968
247 POSITIVE REGULATION OF TRANSMEMBRANE TRANSPORT 16 131 3.987e-05 0.0007511
248 REGULATION OF HEART CONTRACTION 22 221 4.092e-05 0.0007666
249 STEM CELL DIFFERENTIATION 20 190 4.113e-05 0.0007666
250 MUSCLE CELL DIFFERENTIATION 23 237 4.119e-05 0.0007666
251 REGULATION OF STRIATED MUSCLE CONTRACTION 12 79 4.27e-05 0.0007916
252 RESPONSE TO REACTIVE OXYGEN SPECIES 20 191 4.433e-05 0.0008185
253 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 57 867 4.617e-05 0.0008458
254 POSITIVE REGULATION OF MAP KINASE ACTIVITY 21 207 4.608e-05 0.0008458
255 REGULATION OF MUSCLE CONTRACTION 17 147 4.688e-05 0.0008554
256 POSITIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 18 162 4.841e-05 0.0008798
257 DEVELOPMENTAL MATURATION 20 193 5.14e-05 0.0009307
258 REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 10 57 5.234e-05 0.000944
259 MESENCHYMAL CELL DIFFERENTIATION 16 134 5.268e-05 0.0009464
260 GLOMERULAR EPITHELIUM DEVELOPMENT 6 19 5.355e-05 0.0009582
261 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 25 274 5.413e-05 0.0009651
262 REGULATION OF SEQUESTERING OF CALCIUM ION 14 107 5.586e-05 0.0009883
263 REGULATION OF CYTOKINE SECRETION 17 149 5.569e-05 0.0009883
264 ACTIN FILAMENT BASED PROCESS 35 450 5.784e-05 0.001016
265 CELL GROWTH 16 135 5.769e-05 0.001016
266 REGULATION OF MUSCLE SYSTEM PROCESS 20 195 5.947e-05 0.00104
267 IMMUNE SYSTEM DEVELOPMENT 42 582 6.193e-05 0.001079
268 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 11 70 6.431e-05 0.001116
269 RESPONSE TO OXYGEN LEVELS 27 311 6.532e-05 0.00113
270 REGULATION OF DEFENSE RESPONSE 51 759 6.716e-05 0.001153
271 REGULATION OF MACROPHAGE DERIVED FOAM CELL DIFFERENTIATION 7 28 6.715e-05 0.001153
272 REGULATION OF ADAPTIVE IMMUNE RESPONSE 15 123 7.013e-05 0.001191
273 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 21 213 6.989e-05 0.001191
274 MULTI MULTICELLULAR ORGANISM PROCESS 21 213 6.989e-05 0.001191
275 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 24 262 7.124e-05 0.001205
276 RELAXATION OF MUSCLE 6 20 7.403e-05 0.001248
277 SUBSTRATE ADHESION DEPENDENT CELL SPREADING 8 38 7.652e-05 0.001285
278 SECRETION 42 588 7.791e-05 0.001302
279 REGULATION OF AXONOGENESIS 18 168 7.807e-05 0.001302
280 TISSUE MIGRATION 12 84 7.918e-05 0.001311
281 POSITIVE REGULATION OF CATION TRANSMEMBRANE TRANSPORT 13 97 7.945e-05 0.001311
282 POSITIVE REGULATION OF OSSIFICATION 12 84 7.918e-05 0.001311
283 AGING 24 264 8.027e-05 0.00132
284 REGULATION OF BLOOD PRESSURE 18 169 8.433e-05 0.001382
285 POSITIVE REGULATION OF CHEMOKINE PRODUCTION 9 49 8.52e-05 0.001391
286 UROGENITAL SYSTEM DEVELOPMENT 26 299 8.632e-05 0.001404
287 REGULATION OF PROTEIN LOCALIZATION 60 950 9.044e-05 0.001466
288 SYNAPTIC SIGNALING 33 424 9.22e-05 0.001484
289 REGULATION OF IMMUNE EFFECTOR PROCESS 33 424 9.22e-05 0.001484
290 REGULATION OF PHOSPHOLIPASE C ACTIVITY 8 39 9.307e-05 0.001493
291 REGULATION OF ORGAN GROWTH 11 73 9.533e-05 0.001524
292 COGNITION 23 251 9.955e-05 0.001586
293 NEGATIVE REGULATION OF ION TRANSPORT 15 127 0.0001014 0.00161
294 REGULATION OF NEURON DEATH 23 252 0.0001057 0.001673
295 MEMBRANE BIOGENESIS 7 30 0.000108 0.001704
296 FOREBRAIN CELL MIGRATION 10 62 0.0001098 0.001725
297 FOREBRAIN DEVELOPMENT 29 357 0.000116 0.001807
298 HEART DEVELOPMENT 35 466 0.0001157 0.001807
299 RESPONSE TO PURINE CONTAINING COMPOUND 17 158 0.0001161 0.001807
300 POSITIVE REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 5 14 0.0001198 0.001852
301 CAMP CATABOLIC PROCESS 5 14 0.0001198 0.001852
302 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL 11 75 0.0001225 0.001887
303 TUBE MORPHOGENESIS 27 323 0.0001233 0.001894
304 REGULATION OF CELL KILLING 10 63 0.0001261 0.00193
305 POSITIVE REGULATION OF CATABOLIC PROCESS 31 395 0.0001283 0.001957
306 HOMEOSTASIS OF NUMBER OF CELLS 18 175 0.0001321 0.002008
307 NEGATIVE REGULATION OF MUSCLE CONTRACTION 6 22 0.0001335 0.002016
308 CELL PROJECTION ORGANIZATION 57 902 0.0001336 0.002016
309 RENAL SYSTEM PROCESS 13 102 0.0001339 0.002016
310 RESPONSE TO FIBROBLAST GROWTH FACTOR 14 116 0.0001356 0.002035
311 POSITIVE REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 9 52 0.0001378 0.002055
312 REGULATION OF LIPID CATABOLIC PROCESS 9 52 0.0001378 0.002055
313 DIVALENT INORGANIC CATION HOMEOSTASIS 28 343 0.0001392 0.00207
314 LEARNING 15 131 0.0001441 0.002135
315 ION TRANSPORT 74 1262 0.0001481 0.002181
316 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 13 103 0.000148 0.002181
317 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 14 117 0.0001487 0.002183
318 LEUKOCYTE DIFFERENTIATION 25 292 0.0001497 0.00219
319 POSITIVE REGULATION OF PHOSPHOLIPASE ACTIVITY 9 53 0.0001604 0.00234
320 REGULATION OF HEART GROWTH 8 42 0.0001614 0.002347
321 CELLULAR RESPONSE TO REACTIVE OXYGEN SPECIES 13 104 0.0001633 0.002367
322 REGULATION OF CHEMOKINE PRODUCTION 10 65 0.0001649 0.002382
323 RESPONSE TO MECHANICAL STIMULUS 20 210 0.0001653 0.002382
324 POSITIVE REGULATION OF MACROPHAGE DERIVED FOAM CELL DIFFERENTIATION 5 15 0.0001741 0.002492
325 NEGATIVE REGULATION OF SMOOTH MUSCLE CONTRACTION 5 15 0.0001741 0.002492
326 CELL SUBSTRATE ADHESION 17 164 0.0001831 0.002613
327 POSITIVE REGULATION OF LIPASE ACTIVITY 10 66 0.0001878 0.002672
328 CEREBRAL CORTEX CELL MIGRATION 8 43 0.0001917 0.00272
329 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 21 229 0.0001946 0.002749
330 REGULATION OF DENDRITE DEVELOPMENT 14 120 0.0001949 0.002749
331 REGULATION OF SYNAPSE ASSEMBLY 11 79 0.0001968 0.002767
332 NEGATIVE REGULATION OF LOCOMOTION 23 263 0.0001993 0.002793
333 POSITIVE REGULATION OF RESPONSE TO CYTOKINE STIMULUS 7 33 0.0002052 0.002867
334 REGULATION OF VESICLE MEDIATED TRANSPORT 34 462 0.0002114 0.002943
335 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 17 166 0.0002119 0.002943
336 RESPONSE TO OXIDATIVE STRESS 28 352 0.0002144 0.002969
337 EPITHELIAL CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 6 24 0.0002256 0.003115
338 MORPHOGENESIS OF A BRANCHING STRUCTURE 17 167 0.0002277 0.003134
339 TAXIS 34 464 0.0002291 0.003144
340 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 16 152 0.0002352 0.003219
341 POSITIVE REGULATION OF HOMEOSTATIC PROCESS 20 216 0.000241 0.003288
342 POSITIVE REGULATION OF INTERLEUKIN 6 PRODUCTION 10 68 0.0002416 0.003288
343 ORGAN MORPHOGENESIS 53 841 0.0002446 0.003317
344 REGULATION OF FATTY ACID BETA OXIDATION 5 16 0.0002453 0.003317
345 CELLULAR RESPONSE TO OXIDATIVE STRESS 18 184 0.0002479 0.003343
346 EPITHELIUM DEVELOPMENT 58 945 0.00025 0.003362
347 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 16 153 0.0002536 0.0034
348 POSITIVE REGULATION OF AXONOGENESIS 10 69 0.0002731 0.003649
349 NEGATIVE REGULATION OF CELL PROLIFERATION 43 643 0.0002737 0.003649
350 ENDOTHELIAL CELL MIGRATION 9 57 0.0002842 0.003779
351 REGULATION OF VOLTAGE GATED CALCIUM CHANNEL ACTIVITY 6 25 0.0002874 0.003809
352 REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION 19 203 0.0002979 0.003938
353 CYTOKINE MEDIATED SIGNALING PATHWAY 33 452 0.0003007 0.003964
354 REGULATION OF POTASSIUM ION TRANSPORT 11 83 0.0003063 0.004026
355 NEURAL PRECURSOR CELL PROLIFERATION 10 70 0.0003079 0.004035
356 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 24 289 0.0003168 0.004141
357 CELLULAR CHEMICAL HOMEOSTASIS 39 570 0.0003323 0.004331
358 REGULATION OF IMMUNOGLOBULIN SECRETION 5 17 0.0003366 0.00435
359 REGULATION OF PROTEIN KINASE A SIGNALING 5 17 0.0003366 0.00435
360 ACTIVATION OF PROTEIN KINASE A ACTIVITY 5 17 0.0003366 0.00435
361 FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 11 84 0.0003405 0.004388
362 POSITIVE REGULATION OF BINDING 14 127 0.0003531 0.004538
363 REGULATION OF CELLULAR RESPONSE TO STRESS 45 691 0.0003546 0.004546
364 NEGATIVE REGULATION OF LEUKOCYTE MEDIATED IMMUNITY 8 47 0.0003635 0.004559
365 NEGATIVE REGULATION OF BLOOD CIRCULATION 7 36 0.000363 0.004559
366 CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 7 36 0.000363 0.004559
367 VASODILATION 6 26 0.0003616 0.004559
368 REGULATION OF SENSORY PERCEPTION 7 36 0.000363 0.004559
369 NEGATIVE REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY 7 36 0.000363 0.004559
370 REGULATION OF AMINO ACID TRANSPORT 6 26 0.0003616 0.004559
371 REGULATION OF SENSORY PERCEPTION OF PAIN 7 36 0.000363 0.004559
372 NEGATIVE REGULATION OF CELL ADHESION 20 223 0.0003663 0.004582
373 VASCULOGENESIS 9 59 0.000371 0.004628
374 REGULATION OF STEM CELL DIFFERENTIATION 13 113 0.0003746 0.004661
375 HEART PROCESS 11 85 0.0003779 0.004688
376 NEURON PROJECTION MORPHOGENESIS 30 402 0.0003871 0.00479
377 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 18 191 0.0003915 0.004832
378 CELLULAR RESPONSE TO ACID CHEMICAL 17 175 0.0003958 0.004872
379 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 15 144 0.000408 0.004983
380 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 15 144 0.000408 0.004983
381 REGULATION OF RESPONSE TO CYTOKINE STIMULUS 15 144 0.000408 0.004983
382 MUSCLE ORGAN DEVELOPMENT 23 277 0.0004196 0.005098
383 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 11 86 0.0004186 0.005098
384 REGULATION OF GLUCOSE IMPORT 9 60 0.0004219 0.005099
385 LEUKOCYTE HOMEOSTASIS 9 60 0.0004219 0.005099
386 NEGATIVE REGULATION OF ADAPTIVE IMMUNE RESPONSE 7 37 0.0004331 0.005208
387 CARDIAC MUSCLE CELL ACTION POTENTIAL 7 37 0.0004331 0.005208
388 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 23 278 0.0004414 0.005294
389 NEPHRON DEVELOPMENT 13 115 0.0004447 0.005319
390 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 5 18 0.0004515 0.005373
391 ORGAN MATURATION 5 18 0.0004515 0.005373
392 TISSUE REMODELING 11 87 0.000463 0.005496
393 POSITIVE REGULATION OF SYNAPSE ASSEMBLY 9 61 0.0004784 0.005664
394 REGULATION OF NUCLEOTIDE METABOLIC PROCESS 19 211 0.0004838 0.005714
395 PHOSPHATIDYLINOSITOL 3 PHOSPHATE BIOSYNTHETIC PROCESS 8 49 0.0004875 0.005732
396 REGULATION OF INTRACELLULAR TRANSPORT 41 621 0.0004878 0.005732
397 REGULATION OF CATION CHANNEL ACTIVITY 11 88 0.0005112 0.005992
398 COLLAGEN FIBRIL ORGANIZATION 7 38 0.0005137 0.005996
399 POSITIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 17 179 0.0005142 0.005996
400 REGULATION OF RECEPTOR ACTIVITY 13 117 0.0005256 0.006099
401 LEUKOCYTE CHEMOTAXIS 13 117 0.0005256 0.006099
402 SECRETION BY CELL 34 486 0.0005304 0.00614
403 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 9 62 0.000541 0.006247
404 RIBONUCLEOTIDE CATABOLIC PROCESS 6 28 0.0005545 0.006351
405 REGULATION OF ORGANIC ACID TRANSPORT 8 50 0.0005612 0.006351
406 REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 8 50 0.0005612 0.006351
407 ANION TRANSPORT 35 507 0.0005623 0.006351
408 REGULATION OF CYTOKINE SECRETION INVOLVED IN IMMUNE RESPONSE 4 11 0.0005595 0.006351
409 REGULATION OF CHRONIC INFLAMMATORY RESPONSE 4 11 0.0005595 0.006351
410 MUSCLE HYPERTROPHY 6 28 0.0005545 0.006351
411 REGULATION OF FATTY ACID OXIDATION 6 28 0.0005545 0.006351
412 POSITIVE REGULATION OF NFAT PROTEIN IMPORT INTO NUCLEUS 4 11 0.0005595 0.006351
413 RESPONSE TO MUSCLE STRETCH 5 19 0.0005936 0.006655
414 REGULATION OF CARDIAC MUSCLE CONTRACTION BY REGULATION OF THE RELEASE OF SEQUESTERED CALCIUM ION 5 19 0.0005936 0.006655
415 MUSCLE CELL CELLULAR HOMEOSTASIS 5 19 0.0005936 0.006655
416 POSITIVE REGULATION OF TRANSPORTER ACTIVITY 10 76 0.0006035 0.00675
417 LONG TERM SYNAPTIC POTENTIATION 7 39 0.0006057 0.006758
418 LEUKOCYTE ACTIVATION 30 414 0.0006283 0.006993
419 NEURAL CREST CELL MIGRATION 8 51 0.0006437 0.007149
420 CEREBRAL CORTEX DEVELOPMENT 12 105 0.0006604 0.007316
421 INFLAMMATORY RESPONSE 32 454 0.0006741 0.007451
422 NEGATIVE REGULATION OF SECRETION 18 200 0.0006779 0.007475
423 ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE ANTIGEN VIA MHC CLASS I 11 91 0.0006819 0.007501
424 LYMPHOCYTE ACTIVATION 26 342 0.0007029 0.007714
425 HINDBRAIN MORPHOGENESIS 7 40 0.0007103 0.007777
426 POSITIVE REGULATION OF CALCIUM ION TRANSPORT 12 106 0.0007194 0.007821
427 TRANSITION METAL ION HOMEOSTASIS 12 106 0.0007194 0.007821
428 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 35 514 0.0007181 0.007821
429 RESPONSE TO ALCOHOL 27 362 0.0007483 0.008116
430 SKELETAL MUSCLE ORGAN DEVELOPMENT 14 137 0.0007612 0.008237
431 CELLULAR RESPONSE TO RETINOIC ACID 9 65 0.0007702 0.008315
432 PALLIUM DEVELOPMENT 15 153 0.0007738 0.008335
433 RESPONSE TO STEROID HORMONE 34 497 0.0007848 0.008433
434 NEGATIVE REGULATION OF CATABOLIC PROCESS 18 203 0.0008069 0.008651
435 SINGLE ORGANISM CELL ADHESION 32 459 0.0008097 0.008661
436 CELLULAR RESPONSE TO EPINEPHRINE STIMULUS 4 12 0.000814 0.008687
437 DENDRITE DEVELOPMENT 10 79 0.0008222 0.008755
438 RESPONSE TO INORGANIC SUBSTANCE 33 479 0.0008272 0.008788
439 REGULATION OF LEUKOCYTE MEDIATED CYTOTOXICITY 8 53 0.000838 0.008882
440 RESPONSE TO ORGANOPHOSPHORUS 14 139 0.0008786 0.009292
441 REGULATION OF CYTOPLASMIC TRANSPORT 33 481 0.0008875 0.009364
442 ACTION POTENTIAL 11 94 0.0008974 0.009447
443 RESPONSE TO INSULIN 18 205 0.000904 0.009495
444 MUSCLE TISSUE DEVELOPMENT 22 275 0.0009099 0.009509
445 INSULIN RECEPTOR SIGNALING PATHWAY 10 80 0.0009082 0.009509
446 MONOCARBOXYLIC ACID TRANSPORT 13 124 0.0009135 0.009509
447 INOSITOL LIPID MEDIATED SIGNALING 13 124 0.0009135 0.009509
448 RESPONSE TO HYDROGEN PEROXIDE 12 109 0.0009235 0.009592
449 REGULATION OF ACTIN FILAMENT BASED PROCESS 24 312 0.0009432 0.009753
450 REGULATION OF SYNAPTIC PLASTICITY 14 140 0.0009428 0.009753
451 NEGATIVE REGULATION OF RESPONSE TO WOUNDING 15 156 0.0009456 0.009756
452 NEGATIVE REGULATION OF REPRODUCTIVE PROCESS 8 54 0.0009514 0.009794
453 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 9 67 0.0009629 0.00989
454 REGULATION OF RUFFLE ASSEMBLY 5 21 0.0009751 0.009949
455 CHONDROCYTE DEVELOPMENT 5 21 0.0009751 0.009949
456 NEGATIVE REGULATION OF LIPID CATABOLIC PROCESS 5 21 0.0009751 0.009949
NumGOOverlapSizeP ValueAdj. P Value
1 RECEPTOR BINDING 102 1476 2.848e-09 2.646e-06
2 PROTEIN DOMAIN SPECIFIC BINDING 54 624 1.862e-08 8.648e-06
3 KINASE BINDING 48 606 1.535e-06 0.0003564
4 LIPID BINDING 51 657 1.307e-06 0.0003564
5 GROWTH FACTOR RECEPTOR BINDING 18 129 1.994e-06 0.0003706
6 ENZYME BINDING 102 1737 7.073e-06 0.001095
7 ACTIN BINDING 34 393 8.328e-06 0.001105
8 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 30 328 9.599e-06 0.001115
9 CYTOSKELETAL PROTEIN BINDING 56 819 1.817e-05 0.001875
10 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ACTIVITY 7 25 3.013e-05 0.002216
11 SIGNAL TRANSDUCER ACTIVITY 99 1731 2.853e-05 0.002216
12 PROTEIN KINASE ACTIVITY 46 640 3.083e-05 0.002216
13 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 28 315 3.165e-05 0.002216
14 PHOSPHORIC DIESTER HYDROLASE ACTIVITY 13 90 3.578e-05 0.002216
15 BINDING BRIDGING 19 173 3.544e-05 0.002216
16 PROTEIN TYROSINE KINASE ACTIVITY 19 176 4.496e-05 0.002611
17 PROTEIN COMPLEX BINDING 60 935 5.809e-05 0.002998
18 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 22 226 5.739e-05 0.002998
19 KINASE ACTIVITY 55 842 7.444e-05 0.00364
20 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 44 629 8.563e-05 0.003977
21 MOLECULAR FUNCTION REGULATOR 79 1353 0.0001008 0.004458
22 GATED CHANNEL ACTIVITY 27 325 0.0001366 0.005085
23 SH3 DOMAIN BINDING 14 116 0.0001356 0.005085
24 RECEPTOR ACTIVITY 92 1649 0.0001368 0.005085
25 PHOSPHOLIPID BINDING 29 360 0.0001341 0.005085
26 X3 5 CYCLIC AMP PHOSPHODIESTERASE ACTIVITY 5 15 0.0001741 0.005335
27 PROTEIN KINASE A BINDING 8 42 0.0001614 0.005335
28 X1 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 8 43 0.0001917 0.005335
29 PHOSPHORIC ESTER HYDROLASE ACTIVITY 29 368 0.0001952 0.005335
30 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 21 228 0.0001832 0.005335
31 CALMODULIN BINDING 18 179 0.0001758 0.005335
32 IDENTICAL PROTEIN BINDING 71 1209 0.0001936 0.005335
33 PROTEIN KINASE A CATALYTIC SUBUNIT BINDING 5 15 0.0001741 0.005335
34 MACROMOLECULAR COMPLEX BINDING 80 1399 0.0001781 0.005335
35 ACTIN FILAMENT BINDING 14 121 0.0002129 0.00565
36 PASSIVE TRANSMEMBRANE TRANSPORTER ACTIVITY 34 464 0.0002291 0.005911
37 PROTEIN KINASE A REGULATORY SUBUNIT BINDING 5 16 0.0002453 0.006025
38 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 11 81 0.0002464 0.006025
39 GROWTH FACTOR BINDING 14 123 0.000253 0.006027
40 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 10 70 0.0003079 0.007151
41 HEPARIN BINDING 16 157 0.0003401 0.007705
42 CYCLIC NUCLEOTIDE BINDING 7 36 0.000363 0.00803
43 REGULATORY REGION NUCLEIC ACID BINDING 51 818 0.0004094 0.008845
NumGOOverlapSizeP ValueAdj. P Value
1 CELL JUNCTION 97 1151 1.177e-13 6.873e-11
2 INTRINSIC COMPONENT OF PLASMA MEMBRANE 123 1649 2.784e-13 8.131e-11
3 SYNAPSE 71 754 1.92e-12 3.138e-10
4 NEURON PROJECTION 82 942 2.149e-12 3.138e-10
5 NEURON PART 97 1265 2.904e-11 3.391e-09
6 POSTSYNAPSE 43 378 1.688e-10 1.643e-08
7 CELL SUBSTRATE JUNCTION 43 398 8.554e-10 6.244e-08
8 CELL SURFACE 65 757 8.505e-10 6.244e-08
9 SYNAPSE PART 56 610 1.206e-09 7.825e-08
10 SOMATODENDRITIC COMPARTMENT 58 650 1.755e-09 9.318e-08
11 MEMBRANE REGION 85 1134 1.675e-09 9.318e-08
12 CELL PROJECTION 117 1786 3.807e-09 1.853e-07
13 MEMBRANE MICRODOMAIN 34 288 5.462e-09 2.454e-07
14 PLASMA MEMBRANE PROTEIN COMPLEX 48 510 8.678e-09 3.62e-07
15 DENDRITE 43 451 3.613e-08 1.407e-06
16 ANCHORING JUNCTION 44 489 1.335e-07 4.873e-06
17 ACTIN CYTOSKELETON 41 444 1.796e-07 6e-06
18 SIDE OF MEMBRANE 40 428 1.849e-07 6e-06
19 RECEPTOR COMPLEX 33 327 3.915e-07 1.203e-05
20 CELL CORTEX 27 238 4.555e-07 1.33e-05
21 CYTOPLASMIC REGION 30 287 6.268e-07 1.689e-05
22 CELL LEADING EDGE 34 350 6.361e-07 1.689e-05
23 I BAND 18 121 7.685e-07 1.951e-05
24 PLASMA MEMBRANE RECEPTOR COMPLEX 22 175 9.312e-07 2.266e-05
25 NEURON SPINE 17 121 3.471e-06 7.969e-05
26 PLASMA MEMBRANE REGION 64 929 3.548e-06 7.969e-05
27 POSTSYNAPTIC MEMBRANE 23 205 3.858e-06 8.345e-05
28 CONTRACTILE FIBER 23 211 6.273e-06 0.0001308
29 EXCITATORY SYNAPSE 22 197 6.718e-06 0.0001325
30 CELL BODY 40 494 6.806e-06 0.0001325
31 PERINUCLEAR REGION OF CYTOPLASM 48 642 7.423e-06 0.0001398
32 EXTRACELLULAR MATRIX 36 426 7.68e-06 0.0001402
33 SYNAPTIC MEMBRANE 26 261 8.338e-06 0.0001476
34 MEMBRANE PROTEIN COMPLEX 67 1020 1.014e-05 0.0001742
35 SITE OF POLARIZED GROWTH 18 149 1.559e-05 0.0002529
36 INTRACELLULAR VESICLE 78 1259 1.534e-05 0.0002529
37 GOLGI APPARATUS 86 1445 2.455e-05 0.0003874
38 T TUBULE 9 45 4.212e-05 0.0006472
39 PROTEINACEOUS EXTRACELLULAR MATRIX 30 356 4.563e-05 0.0006833
40 FILOPODIUM 13 94 5.702e-05 0.0008325
41 DENDRITIC SHAFT 8 37 6.248e-05 0.0008688
42 EXTRACELLULAR SPACE 81 1376 6.24e-05 0.0008688
43 CYTOPLASMIC SIDE OF MEMBRANE 18 170 9.103e-05 0.001232
44 ENDOPLASMIC RETICULUM 92 1631 9.281e-05 0.001232
45 CELL PROJECTION PART 59 946 0.0001451 0.001883
46 AXON 32 418 0.0001586 0.002014
47 CILIARY BASE 6 23 0.0001748 0.002172
48 VACUOLE 69 1180 0.0002694 0.003211
49 TRANSPORTER COMPLEX 26 321 0.0002688 0.003211
50 EXTRACELLULAR MATRIX COMPONENT 14 125 0.0002995 0.003429
51 SARCOLEMMA 14 125 0.0002995 0.003429
52 LAMELLIPODIUM 17 172 0.0003232 0.00363
53 PLASMA MEMBRANE RAFT 11 86 0.0004186 0.004613
54 PLATELET ALPHA GRANULE 10 75 0.0005423 0.005865
55 CYTOSKELETON 102 1967 0.0008149 0.008562
56 CELL CELL JUNCTION 28 383 0.000821 0.008562
57 ENDOCYTIC VESICLE 21 256 0.0008574 0.008784

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 MAPK_signaling_pathway_hsa04010 34 295 1.009e-08 5.244e-07
2 cGMP_PKG_signaling_pathway_hsa04022 23 163 6.327e-08 1.317e-06
3 Ras_signaling_pathway_hsa04014 28 232 7.596e-08 1.317e-06
4 PI3K_Akt_signaling_pathway_hsa04151 33 352 2.038e-06 2.65e-05
5 cAMP_signaling_pathway_hsa04024 22 198 7.292e-06 7.584e-05
6 Cytokine_cytokine_receptor_interaction_hsa04060 25 270 4.252e-05 0.0003685
7 Calcium_signaling_pathway_hsa04020 17 182 0.0006219 0.00462
8 Apelin_signaling_pathway_hsa04371 14 137 0.0007612 0.004948
9 Rap1_signaling_pathway_hsa04015 18 206 0.0009563 0.005525
10 Regulation_of_actin_cytoskeleton_hsa04810 18 208 0.001068 0.005556
11 Wnt_signaling_pathway_hsa04310 14 146 0.001417 0.006697
12 FoxO_signaling_pathway_hsa04068 13 132 0.001626 0.007044
13 Gap_junction_hsa04540 10 88 0.001896 0.007585
14 Phagosome_hsa04145 14 152 0.002075 0.007705
15 Phospholipase_D_signaling_pathway_hsa04072 13 146 0.003947 0.01258
16 ECM_receptor_interaction_hsa04512 9 82 0.003983 0.01258
17 Focal_adhesion_hsa04510 16 199 0.004113 0.01258
18 Sphingolipid_signaling_pathway_hsa04071 11 118 0.005477 0.01582
19 Adherens_junction_hsa04520 8 72 0.006014 0.01646
20 Necroptosis_hsa04217 13 164 0.01025 0.02621
21 Neuroactive_ligand_receptor_interaction_hsa04080 19 278 0.01058 0.02621
22 Mitophagy_animal_hsa04137 7 65 0.0117 0.02765
23 Hippo_signaling_pathway_hsa04390 12 154 0.01509 0.03412
24 AMPK_signaling_pathway_hsa04152 10 121 0.01747 0.03785
25 Lysosome_hsa04142 10 123 0.01937 0.04029
26 Jak_STAT_signaling_pathway_hsa04630 12 162 0.0216 0.04306
27 TNF_signaling_pathway_hsa04668 9 108 0.02236 0.04306
28 Cell_adhesion_molecules_.CAMs._hsa04514 11 145 0.02323 0.04314
29 Apoptosis_hsa04210 10 138 0.03874 0.06947
30 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 10 139 0.04039 0.07
31 ErbB_signaling_pathway_hsa04012 7 85 0.04355 0.07305
32 Oocyte_meiosis_hsa04114 9 124 0.04791 0.07786
33 Autophagy_animal_hsa04140 9 128 0.05648 0.08899
34 NF_kappa_B_signaling_pathway_hsa04064 7 95 0.07094 0.1085
35 VEGF_signaling_pathway_hsa04370 5 59 0.07397 0.1099
36 HIF_1_signaling_pathway_hsa04066 7 100 0.08776 0.1268
37 ABC_transporters_hsa02010 4 45 0.09166 0.1288
38 TGF_beta_signaling_pathway_hsa04350 6 84 0.1015 0.1389
39 Autophagy_other_hsa04136 3 32 0.1215 0.162
40 Cellular_senescence_hsa04218 9 160 0.1589 0.2065
41 Tight_junction_hsa04530 9 170 0.2024 0.2567
42 mTOR_signaling_pathway_hsa04150 8 151 0.2199 0.2723
43 Hedgehog_signaling_pathway_hsa04340 3 47 0.2663 0.3221
44 Hippo_signaling_pathway_multiple_species_hsa04392 2 29 0.304 0.3593
45 Phosphatidylinositol_signaling_system_hsa04070 5 99 0.3267 0.3718
46 Endocytosis_hsa04144 11 244 0.3289 0.3718
47 Apoptosis_multiple_species_hsa04215 2 33 0.3604 0.3988
48 Ferroptosis_hsa04216 2 40 0.4544 0.4923
49 p53_signaling_pathway_hsa04115 3 68 0.4833 0.5128
50 Peroxisome_hsa04146 3 83 0.6184 0.6431
51 Cell_cycle_hsa04110 4 124 0.7012 0.7149

Quest ID: d1572bfb3c3a56677d4bcb9c6929645b