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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-200c-3p DUSP1 -0.1 0.71696 -2.02 0 MirTarget; miRNATAP -0.1 0.00452 NA
2 hsa-miR-324-3p DUSP1 0.26 0.05061 -2.02 0 MirTarget -0.52 0 NA
3 hsa-miR-331-5p DUSP1 0.21 0.12077 -2.02 0 PITA; miRNATAP -0.29 0.00017 NA
4 hsa-miR-425-3p DUSP1 -0.16 0.22372 -2.02 0 MirTarget -0.33 7.0E-5 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 CELL CYCLE 47 1316 6.438e-29 2.996e-25
2 REGULATION OF CELL CYCLE 38 949 1.258e-24 1.951e-21
3 CELL CYCLE PROCESS 40 1081 9.651e-25 1.951e-21
4 CELL DIVISION 27 460 1.495e-21 1.654e-18
5 PROTEIN PHOSPHORYLATION 35 944 1.777e-21 1.654e-18
6 MITOTIC CELL CYCLE 31 766 4.998e-20 3.876e-17
7 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 44 1977 1.174e-18 7.802e-16
8 NEGATIVE REGULATION OF CELL CYCLE 24 433 1.351e-18 7.855e-16
9 PHOSPHORYLATION 35 1228 7.857e-18 4.062e-15
10 REGULATION OF ORGANELLE ORGANIZATION 34 1178 1.834e-17 8.531e-15
11 REGULATION OF CELL CYCLE PROCESS 25 558 3.629e-17 1.535e-14
12 CELL CYCLE CHECKPOINT 17 194 1.15e-16 4.46e-14
13 REGULATION OF TRANSFERASE ACTIVITY 30 946 1.882e-16 6.736e-14
14 INTRACELLULAR SIGNAL TRANSDUCTION 37 1572 3.386e-16 1.126e-13
15 REGULATION OF PROTEIN MODIFICATION PROCESS 37 1710 4.95e-15 1.535e-12
16 CELL CYCLE PHASE TRANSITION 17 255 1.122e-14 3.262e-12
17 NEGATIVE REGULATION OF CELL CYCLE PROCESS 16 214 1.205e-14 3.298e-12
18 REGULATION OF MITOTIC CELL CYCLE 21 468 1.665e-14 4.305e-12
19 MITOTIC NUCLEAR DIVISION 19 361 1.976e-14 4.838e-12
20 REGULATION OF CHROMOSOME ORGANIZATION 17 278 4.649e-14 1.082e-11
21 PEPTIDYL AMINO ACID MODIFICATION 26 841 5.303e-14 1.121e-11
22 ORGANELLE FISSION 21 496 5.192e-14 1.121e-11
23 CELL CYCLE G2 M PHASE TRANSITION 13 138 2.2e-13 4.451e-11
24 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 29 1152 2.519e-13 4.884e-11
25 CHROMOSOME ORGANIZATION 27 1009 4.903e-13 8.45e-11
26 DNA INTEGRITY CHECKPOINT 13 146 4.578e-13 8.45e-11
27 REGULATION OF CELL CYCLE PHASE TRANSITION 17 321 4.827e-13 8.45e-11
28 POSITIVE REGULATION OF CELL CYCLE 17 332 8.31e-13 1.381e-10
29 REGULATION OF DNA METABOLIC PROCESS 17 340 1.218e-12 1.955e-10
30 POSITIVE REGULATION OF CELL CYCLE PROCESS 15 247 1.794e-12 2.782e-10
31 RESPONSE TO ENDOGENOUS STIMULUS 31 1450 2.267e-12 3.402e-10
32 REGULATION OF CELL DIVISION 15 272 7.165e-12 1.01e-09
33 REGULATION OF PHOSPHORUS METABOLIC PROCESS 32 1618 7.135e-12 1.01e-09
34 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 20 573 7.707e-12 1.055e-09
35 PEPTIDYL SERINE MODIFICATION 12 148 1.164e-11 1.505e-09
36 RESPONSE TO HORMONE 24 893 1.151e-11 1.505e-09
37 REGULATION OF BINDING 15 283 1.261e-11 1.586e-09
38 REGULATION OF CELL DEATH 30 1472 1.893e-11 2.317e-09
39 RESPONSE TO OXYGEN CONTAINING COMPOUND 29 1381 2.205e-11 2.631e-09
40 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 20 616 2.83e-11 3.293e-09
41 HISTONE PHOSPHORYLATION 7 25 3.026e-11 3.434e-09
42 REGULATION OF KINASE ACTIVITY 22 776 3.473e-11 3.848e-09
43 REGULATION OF NUCLEAR DIVISION 12 163 3.639e-11 3.938e-09
44 REGULATION OF CYTOSKELETON ORGANIZATION 18 502 6.3e-11 6.663e-09
45 REGULATION OF CATABOLIC PROCESS 21 731 8.184e-11 8.462e-09
46 CELLULAR RESPONSE TO STRESS 30 1565 8.591e-11 8.69e-09
47 SISTER CHROMATID SEGREGATION 12 176 8.936e-11 8.847e-09
48 NEGATIVE REGULATION OF ORGANELLE ORGANIZATION 16 387 1.016e-10 9.844e-09
49 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 25 1087 1.108e-10 1.052e-08
50 MITOTIC CELL CYCLE CHECKPOINT 11 139 1.142e-10 1.063e-08
51 CELL DEATH 24 1001 1.216e-10 1.108e-08
52 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 32 1805 1.238e-10 1.108e-08
53 POSITIVE REGULATION OF DNA METABOLIC PROCESS 12 185 1.597e-10 1.402e-08
54 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 20 684 1.811e-10 1.561e-08
55 RESPONSE TO ABIOTIC STIMULUS 24 1024 1.931e-10 1.634e-08
56 REGULATION OF CELLULAR RESPONSE TO STRESS 20 691 2.166e-10 1.799e-08
57 NEGATIVE REGULATION OF CELL DEATH 22 872 3.209e-10 2.62e-08
58 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 12 199 3.712e-10 2.978e-08
59 REGULATION OF CHROMOSOME SEGREGATION 9 85 4.453e-10 3.512e-08
60 NEGATIVE REGULATION OF MOLECULAR FUNCTION 24 1079 5.557e-10 4.309e-08
61 REGULATION OF CELL PROLIFERATION 28 1496 7.549e-10 5.759e-08
62 REPRODUCTION 26 1297 8.429e-10 6.326e-08
63 CELL PROLIFERATION 19 672 9.627e-10 7.11e-08
64 CHROMOSOME SEGREGATION 13 272 1.15e-09 8.36e-08
65 RESPONSE TO NITROGEN COMPOUND 21 859 1.528e-09 1.094e-07
66 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 18 616 1.68e-09 1.184e-07
67 NUCLEAR CHROMOSOME SEGREGATION 12 228 1.76e-09 1.222e-07
68 CELLULAR RESPONSE TO HORMONE STIMULUS 17 552 2.293e-09 1.569e-07
69 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 27 1492 3.425e-09 2.283e-07
70 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 10 146 3.434e-09 2.283e-07
71 REGULATION OF MICROTUBULE BASED PROCESS 12 243 3.619e-09 2.372e-07
72 POSITIVE REGULATION OF CHROMOSOME ORGANIZATION 10 150 4.464e-09 2.885e-07
73 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 30 1848 4.583e-09 2.921e-07
74 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 22 1008 4.729e-09 2.973e-07
75 RESPONSE TO ORGANIC CYCLIC COMPOUND 21 917 4.864e-09 3.018e-07
76 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 23 1135 8.028e-09 4.915e-07
77 POSITIVE REGULATION OF MOLECULAR FUNCTION 29 1791 9.561e-09 5.777e-07
78 POSITIVE REGULATION OF MITOTIC CELL CYCLE 9 123 1.216e-08 7.252e-07
79 REGULATION OF PROTEIN BINDING 10 168 1.33e-08 7.836e-07
80 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 15 470 1.379e-08 8.02e-07
81 G2 DNA DAMAGE CHECKPOINT 6 33 1.416e-08 8.131e-07
82 REGULATION OF PROTEOLYSIS 18 711 1.566e-08 8.884e-07
83 EMBRYO DEVELOPMENT 20 894 1.775e-08 9.95e-07
84 CELLULAR RESPONSE TO DNA DAMAGE STIMULUS 18 720 1.898e-08 1.052e-06
85 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 13 351 2.441e-08 1.336e-06
86 SIGNAL TRANSDUCTION IN RESPONSE TO DNA DAMAGE 8 96 2.936e-08 1.588e-06
87 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 27 1656 3.126e-08 1.672e-06
88 REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 8 97 3.186e-08 1.685e-06
89 CYTOSKELETON ORGANIZATION 19 838 3.452e-08 1.805e-06
90 MITOTIC DNA INTEGRITY CHECKPOINT 8 100 4.052e-08 2.095e-06
91 REGULATION OF SISTER CHROMATID SEGREGATION 7 67 4.605e-08 2.354e-06
92 PROTEIN AUTOPHOSPHORYLATION 10 192 4.739e-08 2.397e-06
93 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 16 602 5.569e-08 2.786e-06
94 POSTTRANSCRIPTIONAL REGULATION OF GENE EXPRESSION 14 448 5.683e-08 2.813e-06
95 REGULATION OF CELL CYCLE ARREST 8 108 7.416e-08 3.632e-06
96 INTRINSIC APOPTOTIC SIGNALING PATHWAY 9 152 7.678e-08 3.722e-06
97 POSITIVE REGULATION OF GENE EXPRESSION 27 1733 8.005e-08 3.801e-06
98 RESPONSE TO HYDROGEN PEROXIDE 8 109 7.97e-08 3.801e-06
99 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 18 799 9.177e-08 4.274e-06
100 SISTER CHROMATID COHESION 8 111 9.186e-08 4.274e-06
101 POSITIVE REGULATION OF CATABOLIC PROCESS 13 395 9.691e-08 4.464e-06
102 RESPONSE TO PEPTIDE 13 404 1.257e-07 5.734e-06
103 REPRODUCTIVE SYSTEM DEVELOPMENT 13 408 1.408e-07 6.24e-06
104 REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 11 274 1.395e-07 6.24e-06
105 CELLULAR RESPONSE TO PEPTIDE 11 274 1.395e-07 6.24e-06
106 SPINDLE CHECKPOINT 5 25 1.457e-07 6.397e-06
107 NEGATIVE REGULATION OF CYTOSKELETON ORGANIZATION 10 221 1.77e-07 7.699e-06
108 MICROTUBULE CYTOSKELETON ORGANIZATION 12 348 1.897e-07 8.097e-06
109 REGULATION OF TELOMERE MAINTENANCE VIA TELOMERE LENGTHENING 6 50 1.895e-07 8.097e-06
110 REGULATION OF RESPONSE TO STRESS 24 1468 2.108e-07 8.916e-06
111 RESPONSE TO EXTERNAL STIMULUS 27 1821 2.192e-07 9.188e-06
112 APOPTOTIC SIGNALING PATHWAY 11 289 2.382e-07 9.895e-06
113 CELLULAR RESPONSE TO NITROGEN COMPOUND 14 505 2.46e-07 1.013e-05
114 POSITIVE REGULATION OF PROTEOLYSIS 12 363 2.981e-07 1.217e-05
115 REGULATION OF LIGASE ACTIVITY 8 130 3.124e-07 1.264e-05
116 NEGATIVE REGULATION OF BINDING 8 131 3.313e-07 1.329e-05
117 POSITIVE REGULATION OF CELL DEATH 15 605 3.68e-07 1.463e-05
118 REGULATION OF HOMEOSTATIC PROCESS 13 447 3.994e-07 1.575e-05
119 REGULATION OF DNA BIOSYNTHETIC PROCESS 7 94 4.85e-07 1.896e-05
120 PROTEIN DEPHOSPHORYLATION 9 190 5.132e-07 1.99e-05
121 POSITIVE REGULATION OF DNA BIOSYNTHETIC PROCESS 6 59 5.18e-07 1.992e-05
122 RESPONSE TO REACTIVE OXYGEN SPECIES 9 191 5.363e-07 2.045e-05
123 NEGATIVE REGULATION OF CHROMOSOME ORGANIZATION 7 96 5.601e-07 2.119e-05
124 REGULATION OF PROTEIN CATABOLIC PROCESS 12 393 6.924e-07 2.598e-05
125 PEPTIDYL TYROSINE DEPHOSPHORYLATION 7 100 7.399e-07 2.754e-05
126 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 8 147 7.986e-07 2.949e-05
127 REGULATION OF PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 8 148 8.407e-07 3.08e-05
128 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 19 1036 9.083e-07 3.261e-05
129 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 19 1036 9.083e-07 3.261e-05
130 REGULATION OF CYTOPLASMIC TRANSPORT 13 481 9.112e-07 3.261e-05
131 CELLULAR RESPONSE TO UV 6 66 1.015e-06 3.606e-05
132 REGULATION OF EARLY ENDOSOME TO LATE ENDOSOME TRANSPORT 4 16 1.064e-06 3.751e-05
133 DNA REPLICATION 9 208 1.094e-06 3.827e-05
134 REGULATION OF TELOMERE MAINTENANCE 6 67 1.11e-06 3.856e-05
135 RESPONSE TO RADIATION 12 413 1.166e-06 4.018e-05
136 REGULATION OF CELLULAR LOCALIZATION 21 1277 1.293e-06 4.423e-05
137 IMMUNE SYSTEM DEVELOPMENT 14 582 1.337e-06 4.542e-05
138 COVALENT CHROMATIN MODIFICATION 11 345 1.367e-06 4.609e-05
139 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 22 1395 1.38e-06 4.619e-05
140 NEGATIVE REGULATION OF PHOSPHORYLATION 12 422 1.46e-06 4.851e-05
141 POSITIVE REGULATION OF CATALYTIC ACTIVITY 23 1518 1.501e-06 4.883e-05
142 REGULATION OF CENTROSOME CYCLE 5 39 1.493e-06 4.883e-05
143 NEUROGENESIS 22 1402 1.499e-06 4.883e-05
144 REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 10 280 1.543e-06 4.952e-05
145 RESPONSE TO LIGHT STIMULUS 10 280 1.543e-06 4.952e-05
146 REGULATION OF DNA REPLICATION 8 161 1.587e-06 5.059e-05
147 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 10 282 1.645e-06 5.207e-05
148 RESPONSE TO OXIDATIVE STRESS 11 352 1.661e-06 5.223e-05
149 REGULATION OF UBIQUITIN PROTEIN LIGASE ACTIVITY 4 18 1.775e-06 5.544e-05
150 G1 DNA DAMAGE CHECKPOINT 6 73 1.849e-06 5.734e-05
151 REGULATION OF DEVELOPMENTAL GROWTH 10 289 2.05e-06 6.317e-05
152 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 11 360 2.065e-06 6.322e-05
153 REGULATION OF APOPTOTIC SIGNALING PATHWAY 11 363 2.237e-06 6.804e-05
154 MICROTUBULE BASED PROCESS 13 522 2.256e-06 6.816e-05
155 POSITIVE REGULATION OF RESPONSE TO STIMULUS 26 1929 2.396e-06 7.194e-05
156 REGULATION OF TELOMERASE ACTIVITY 5 43 2.457e-06 7.328e-05
157 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 8 171 2.492e-06 7.387e-05
158 ANAPHASE PROMOTING COMPLEX DEPENDENT CATABOLIC PROCESS 6 77 2.533e-06 7.46e-05
159 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 11 370 2.689e-06 7.842e-05
160 RHYTHMIC PROCESS 10 298 2.696e-06 7.842e-05
161 REGULATION OF INTRACELLULAR TRANSPORT 14 621 2.851e-06 8.238e-05
162 POSITIVE REGULATION OF CELL PROLIFERATION 16 814 3.075e-06 8.831e-05
163 CENTROSOME CYCLE 5 45 3.094e-06 8.831e-05
164 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 13 541 3.337e-06 9.409e-05
165 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 13 541 3.337e-06 9.409e-05
166 REGULATION OF FIBROBLAST PROLIFERATION 6 81 3.411e-06 9.562e-05
167 RESPONSE TO UV 7 126 3.507e-06 9.771e-05
168 SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR 7 127 3.696e-06 0.0001024
169 REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS 8 181 3.803e-06 0.0001047
170 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 16 829 3.883e-06 0.0001063
171 NEGATIVE REGULATION OF GENE EXPRESSION 22 1493 4.195e-06 0.0001141
172 MICROTUBULE ORGANIZING CENTER ORGANIZATION 6 84 4.221e-06 0.0001142
173 CELLULAR RESPONSE TO OXIDATIVE STRESS 8 184 4.295e-06 0.0001155
174 POSITIVE REGULATION OF CELL CYCLE ARREST 6 85 4.523e-06 0.000121
175 REGULATION OF CELL PROJECTION ORGANIZATION 13 558 4.67e-06 0.0001235
176 PEPTIDYL TYROSINE MODIFICATION 8 186 4.653e-06 0.0001235
177 POSITIVE REGULATION OF CELL DIVISION 7 132 4.776e-06 0.0001256
178 RESPONSE TO INORGANIC SUBSTANCE 12 479 5.37e-06 0.0001404
179 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 22 1517 5.424e-06 0.000141
180 TUBE MORPHOGENESIS 10 323 5.504e-06 0.0001423
181 POSITIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 8 192 5.879e-06 0.0001511
182 DNA METABOLIC PROCESS 15 758 5.974e-06 0.0001527
183 REGULATION OF RNA STABILITY 7 139 6.718e-06 0.0001692
184 CELLULAR RESPONSE TO LIGHT STIMULUS 6 91 6.727e-06 0.0001692
185 MITOTIC SISTER CHROMATID SEGREGATION 6 91 6.727e-06 0.0001692
186 POSITIVE REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 8 196 6.841e-06 0.0001711
187 POSITIVE REGULATION OF FIBROBLAST PROLIFERATION 5 53 7.038e-06 0.0001751
188 POSITIVE REGULATION OF CHROMOSOME SEGREGATION 4 25 7.143e-06 0.0001768
189 POSITIVE REGULATION OF PROTEIN CATABOLIC PROCESS 9 263 7.463e-06 0.0001837
190 REGULATION OF DNA BINDING 6 93 7.631e-06 0.0001869
191 RESPONSE TO LIPID 16 888 9.24e-06 0.0002251
192 RESPONSE TO INSULIN 8 205 9.5e-06 0.000229
193 PROTEASOMAL PROTEIN CATABOLIC PROCESS 9 271 9.494e-06 0.000229
194 MULTI ORGANISM REPRODUCTIVE PROCESS 16 891 9.637e-06 0.0002311
195 NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 6 98 1.033e-05 0.0002464
196 POSITIVE REGULATION OF TELOMERASE ACTIVITY 4 28 1.143e-05 0.0002699
197 NEGATIVE REGULATION OF CHROMOSOME SEGREGATION 4 28 1.143e-05 0.0002699
198 NEGATIVE REGULATION OF CELL DIVISION 5 60 1.302e-05 0.0003045
199 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 11 437 1.3e-05 0.0003045
200 REGULATION OF VACUOLAR TRANSPORT 4 29 1.32e-05 0.0003072
201 REGULATION OF PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 6 103 1.374e-05 0.0003182
202 NEGATIVE REGULATION OF CELLULAR CATABOLIC PROCESS 7 156 1.429e-05 0.0003292
203 DEPHOSPHORYLATION 9 286 1.459e-05 0.0003328
204 CELLULAR RESPONSE TO REACTIVE OXYGEN SPECIES 6 104 1.453e-05 0.0003328
205 LEUKOCYTE DIFFERENTIATION 9 292 1.72e-05 0.0003904
206 CHROMATIN MODIFICATION 12 539 1.752e-05 0.0003957
207 REGULATION OF PROTEIN ACETYLATION 5 64 1.789e-05 0.0004022
208 REGULATION OF SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR 7 162 1.825e-05 0.0004083
209 REGULATION OF MITOTIC SPINDLE CHECKPOINT 3 11 2.003e-05 0.0004375
210 POSITIVE REGULATION OF LIGASE ACTIVITY 6 110 2.001e-05 0.0004375
211 ORGANELLE INHERITANCE 3 11 2.003e-05 0.0004375
212 REGULATION OF MITOTIC CELL CYCLE SPINDLE ASSEMBLY CHECKPOINT 3 11 2.003e-05 0.0004375
213 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 4 32 1.976e-05 0.0004375
214 CELL CYCLE G1 S PHASE TRANSITION 6 111 2.107e-05 0.000456
215 G1 S TRANSITION OF MITOTIC CELL CYCLE 6 111 2.107e-05 0.000456
216 TUBE DEVELOPMENT 12 552 2.216e-05 0.0004751
217 REGULATION OF CELLULAR PROTEIN LOCALIZATION 12 552 2.216e-05 0.0004751
218 POSITIVE REGULATION OF TELOMERE MAINTENANCE VIA TELOMERE LENGTHENING 4 33 2.24e-05 0.0004781
219 POSITIVE REGULATION OF CELL CYCLE PHASE TRANSITION 5 68 2.408e-05 0.0005116
220 NEGATIVE REGULATION OF MITOTIC NUCLEAR DIVISION 4 34 2.529e-05 0.0005348
221 CELL DEVELOPMENT 20 1426 2.555e-05 0.0005379
222 PROTEIN SUMOYLATION 6 115 2.576e-05 0.0005399
223 ESTABLISHMENT OF LOCALIZATION IN CELL 22 1676 2.599e-05 0.0005422
224 CELL ACTIVATION 12 568 2.931e-05 0.0006089
225 REGULATION OF CELLULAR COMPONENT BIOGENESIS 14 767 3.08e-05 0.0006369
226 POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 4 36 3.187e-05 0.0006562
227 POSITIVE REGULATION OF KINASE ACTIVITY 11 482 3.206e-05 0.0006571
228 REGULATION OF MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION 7 178 3.344e-05 0.0006825
229 MORPHOGENESIS OF AN EPITHELIUM 10 400 3.485e-05 0.000708
230 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 10 404 3.79e-05 0.0007667
231 LOCOMOTION 17 1114 4.003e-05 0.0008063
232 REGULATION OF SPINDLE CHECKPOINT 3 14 4.37e-05 0.0008764
233 MEIOTIC CELL CYCLE 7 186 4.426e-05 0.0008838
234 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 19 1360 4.445e-05 0.0008839
235 NEGATIVE REGULATION OF PROTEIN BINDING 5 79 4.982e-05 0.0009865
236 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 17 1142 5.456e-05 0.001071
237 POSITIVE REGULATION OF NUCLEASE ACTIVITY 3 15 5.442e-05 0.001071
238 CELLULAR COMPONENT DISASSEMBLY 11 515 5.833e-05 0.00114
239 POSITIVE REGULATION OF PHOSPHOLIPID METABOLIC PROCESS 4 42 5.917e-05 0.001152
240 PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS 6 134 6.084e-05 0.001179
241 TISSUE DEVELOPMENT 20 1518 6.18e-05 0.001193
242 RESPONSE TO DRUG 10 431 6.515e-05 0.001242
243 REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 4 43 6.499e-05 0.001242
244 REGULATION OF INSULIN RECEPTOR SIGNALING PATHWAY 4 43 6.499e-05 0.001242
245 POSITIVE REGULATION OF TELOMERE CAPPING 3 16 6.674e-05 0.001255
246 CYTOKINESIS 5 84 6.69e-05 0.001255
247 FEMALE GENITALIA DEVELOPMENT 3 16 6.674e-05 0.001255
248 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 22 1784 6.686e-05 0.001255
249 CELLULAR RESPONSE TO RADIATION 6 137 6.881e-05 0.001286
250 POSITIVE REGULATION OF CHROMATIN MODIFICATION 5 85 7.08e-05 0.001318
251 POSITIVE REGULATION OF DNA REPLICATION 5 86 7.487e-05 0.001388
252 REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 9 354 7.691e-05 0.001415
253 NEGATIVE REGULATION OF CATABOLIC PROCESS 7 203 7.687e-05 0.001415
254 PROTEIN LOCALIZATION TO CHROMOSOME 4 45 7.786e-05 0.001426
255 RESPONSE TO EXTRACELLULAR STIMULUS 10 441 7.88e-05 0.001438
256 RESPONSE TO ANGIOTENSIN 3 17 8.074e-05 0.001467
257 MEIOSIS I 5 88 8.356e-05 0.001513
258 PLATELET ACTIVATION 6 142 8.394e-05 0.001514
259 PEPTIDYL THREONINE MODIFICATION 4 46 8.494e-05 0.00152
260 NEGATIVE REGULATION OF NUCLEAR DIVISION 4 46 8.494e-05 0.00152
261 RAS PROTEIN SIGNAL TRANSDUCTION 6 143 8.727e-05 0.001556
262 MEMBRANE DISASSEMBLY 4 47 9.249e-05 0.001618
263 REGULATION OF LIPID METABOLIC PROCESS 8 282 9.206e-05 0.001618
264 POSITIVE REGULATION OF TELOMERE MAINTENANCE 4 47 9.249e-05 0.001618
265 NUCLEAR ENVELOPE DISASSEMBLY 4 47 9.249e-05 0.001618
266 RESPONSE TO ALCOHOL 9 362 9.119e-05 0.001618
267 CELL DEATH IN RESPONSE TO OXIDATIVE STRESS 3 18 9.653e-05 0.001676
268 LYMPHOCYTE APOPTOTIC PROCESS 3 18 9.653e-05 0.001676
269 CELLULAR RESPONSE TO INSULIN STIMULUS 6 146 9.786e-05 0.001693
270 ANATOMICAL STRUCTURE HOMEOSTASIS 8 285 9.907e-05 0.001707
271 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 11 554 0.0001116 0.001915
272 POSITIVE REGULATION OF HOMEOSTATIC PROCESS 7 216 0.0001133 0.001938
273 LYMPHOCYTE HOMEOSTASIS 4 50 0.000118 0.002004
274 REGULATION OF ADHERENS JUNCTION ORGANIZATION 4 50 0.000118 0.002004
275 FC GAMMA RECEPTOR SIGNALING PATHWAY 5 95 0.0001202 0.002033
276 REGULATION OF CHROMATIN ORGANIZATION 6 152 0.0001221 0.002051
277 MEIOTIC CELL CYCLE PROCESS 6 152 0.0001221 0.002051
278 REGULATION OF MAPK CASCADE 12 660 0.0001231 0.002061
279 CARDIOCYTE DIFFERENTIATION 5 96 0.0001263 0.002106
280 RESPONSE TO WOUNDING 11 563 0.0001285 0.002128
281 CHROMATIN ORGANIZATION 12 663 0.0001284 0.002128
282 MULTICELLULAR ORGANISM REPRODUCTION 13 768 0.0001291 0.00213
283 CELL CYCLE ARREST 6 154 0.0001312 0.002157
284 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 6 156 0.0001408 0.002307
285 RESPONSE TO GROWTH FACTOR 10 475 0.0001449 0.002365
286 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 15 1004 0.0001514 0.002463
287 LIMBIC SYSTEM DEVELOPMENT 5 100 0.0001531 0.002482
288 B CELL HOMEOSTASIS 3 21 0.0001556 0.002514
289 REGULATION OF CIRCADIAN RHYTHM 5 103 0.0001759 0.002832
290 REGULATION OF TELOMERE CAPPING 3 22 0.0001795 0.00288
291 PEPTIDYL LYSINE MODIFICATION 8 312 0.0001844 0.002949
292 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 13 801 0.0001952 0.003111
293 REGULATION OF NUCLEASE ACTIVITY 3 23 0.0002057 0.003233
294 POSITIVE REGULATION OF MITOCHONDRION ORGANIZATION 6 167 0.000204 0.003233
295 LEUKOCYTE APOPTOTIC PROCESS 3 23 0.0002057 0.003233
296 PROTEIN COMPLEX SUBUNIT ORGANIZATION 19 1527 0.0002051 0.003233
297 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 17 1275 0.0002076 0.003253
298 RESPONSE TO STEROID HORMONE 10 497 0.0002088 0.00326
299 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 10 498 0.0002122 0.003302
300 POSITIVE REGULATION OF CELL COMMUNICATION 19 1532 0.0002139 0.003318
301 REGULATION OF NEURON PROJECTION DEVELOPMENT 9 408 0.0002237 0.003458
302 REGULATION OF CELL CYCLE G2 M PHASE TRANSITION 4 59 0.0002253 0.00346
303 REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 4 59 0.0002253 0.00346
304 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 20 1672 0.0002299 0.003519
305 REGULATION OF RESPONSE TO EXTRACELLULAR STIMULUS 6 171 0.0002318 0.003525
306 REGULATION OF RESPONSE TO NUTRIENT LEVELS 6 171 0.0002318 0.003525
307 HEAD DEVELOPMENT 12 709 0.0002388 0.003619
308 LEUKOCYTE HOMEOSTASIS 4 60 0.0002405 0.003633
309 REGULATION OF PHOSPHOLIPID METABOLIC PROCESS 4 61 0.0002563 0.003848
310 CELLULAR RESPONSE TO HYDROGEN PEROXIDE 4 61 0.0002563 0.003848
311 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 10 514 0.0002732 0.004087
312 EPITHELIUM DEVELOPMENT 14 945 0.0002794 0.004167
313 CELL MOTILITY 13 835 0.0002921 0.004329
314 LOCALIZATION OF CELL 13 835 0.0002921 0.004329
315 REGULATION OF PROTEIN LOCALIZATION 14 950 0.0002948 0.004351
316 REGULATION OF CELL DEVELOPMENT 13 836 0.0002955 0.004351
317 DEVELOPMENTAL PROGRAMMED CELL DEATH 3 26 0.0002987 0.00437
318 FEMALE MEIOTIC DIVISION 3 26 0.0002987 0.00437
319 NEGATIVE REGULATION OF CELL COMMUNICATION 16 1192 0.0003027 0.004416
320 NEGATIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS 4 64 0.0003085 0.004486
321 SEXUAL REPRODUCTION 12 730 0.0003114 0.004514
322 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 14 957 0.0003176 0.004589
323 LYMPHOCYTE ACTIVATION 8 342 0.0003424 0.004932
324 REGULATION OF GROWTH 11 633 0.0003524 0.005029
325 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 12 740 0.0003521 0.005029
326 PROTEOLYSIS 16 1208 0.0003511 0.005029
327 TISSUE MORPHOGENESIS 10 533 0.000364 0.00518
328 POSITIVE REGULATION OF RELEASE OF CYTOCHROME C FROM MITOCHONDRIA 3 28 0.0003736 0.0053
329 CELLULAR RESPONSE TO ABIOTIC STIMULUS 7 263 0.0003773 0.005336
330 AGING 7 264 0.000386 0.005443
331 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 12 750 0.0003973 0.005571
332 EMBRYONIC MORPHOGENESIS 10 539 0.0003975 0.005571
333 SEX DIFFERENTIATION 7 266 0.0004039 0.005643
334 PHAGOCYTOSIS 6 190 0.0004076 0.005678
335 MITOTIC SPINDLE ORGANIZATION 4 69 0.0004117 0.005719
336 REGULATION OF CELL CYCLE CHECKPOINT 3 29 0.0004152 0.005749
337 REGULATION OF MEMBRANE PERMEABILITY 4 70 0.000435 0.006006
338 CENTRAL NERVOUS SYSTEM DEVELOPMENT 13 872 0.0004418 0.006082
339 PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 13 873 0.0004466 0.00613
340 REGULATION OF CELL DIFFERENTIATION 18 1492 0.0004483 0.006136
341 FOREBRAIN DEVELOPMENT 8 357 0.0004553 0.006212
342 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE 4 71 0.0004592 0.006235
343 NEGATIVE REGULATION OF TOR SIGNALING 3 30 0.0004596 0.006235
344 REGULATION OF LIPID BIOSYNTHETIC PROCESS 5 128 0.0004813 0.00651
345 REGULATION OF NEURON DIFFERENTIATION 10 554 0.0004926 0.006644
346 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 5 129 0.0004987 0.006707
347 CHROMOSOME CONDENSATION 3 31 0.000507 0.006779
348 NEGATIVE REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 3 31 0.000507 0.006779
349 CELLULAR RESPONSE TO LIPID 9 457 0.0005116 0.006783
350 REGULATION OF ORGAN GROWTH 4 73 0.0005105 0.006783
351 INTERSPECIES INTERACTION BETWEEN ORGANISMS 11 662 0.0005132 0.006783
352 SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM 11 662 0.0005132 0.006783
353 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 8 365 0.0005269 0.006945
354 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 4 74 0.0005376 0.007026
355 CARDIAC MUSCLE CELL DIFFERENTIATION 4 74 0.0005376 0.007026
356 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 5 131 0.000535 0.007026
357 PROTEIN COMPLEX BIOGENESIS 15 1132 0.0005446 0.007078
358 PROTEIN COMPLEX ASSEMBLY 15 1132 0.0005446 0.007078
359 B CELL ACTIVATION 5 132 0.0005538 0.007178
360 POSITIVE REGULATION OF LIPID KINASE ACTIVITY 3 32 0.0005574 0.007185
361 REGULATION OF CENTROSOME DUPLICATION 3 32 0.0005574 0.007185
362 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 9 465 0.0005794 0.007448
363 HEART DEVELOPMENT 9 466 0.0005884 0.007542
364 MACROMOLECULAR COMPLEX ASSEMBLY 17 1398 0.0006028 0.007706
365 CELL PROJECTION ORGANIZATION 13 902 0.000607 0.007739
366 SIGNAL TRANSDUCTION IN ABSENCE OF LIGAND 3 33 0.0006109 0.007745
367 EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 3 33 0.0006109 0.007745
368 CARDIOVASCULAR SYSTEM DEVELOPMENT 12 788 0.0006163 0.007771
369 CIRCULATORY SYSTEM DEVELOPMENT 12 788 0.0006163 0.007771
370 FC RECEPTOR SIGNALING PATHWAY 6 206 0.0006245 0.007853
371 REGULATION OF PROTEIN COMPLEX ASSEMBLY 8 375 0.000629 0.007888
372 PROTEIN DESTABILIZATION 3 34 0.0006676 0.00835
373 LYMPHOCYTE DIFFERENTIATION 6 209 0.0006736 0.008403
374 PLACENTA DEVELOPMENT 5 138 0.0006777 0.008431
375 RESPONSE TO MECHANICAL STIMULUS 6 210 0.0006906 0.008569
376 PROTEIN CATABOLIC PROCESS 10 579 0.0006928 0.008574
377 NEURON DEVELOPMENT 11 687 0.0006974 0.008608
378 NEGATIVE REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 5 139 0.0007002 0.008619
379 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 11 689 0.0007143 0.008769
380 REGULATION OF FATTY ACID BIOSYNTHETIC PROCESS 3 35 0.0007275 0.008908
381 NUCLEAR ENVELOPE ORGANIZATION 4 81 0.0007566 0.00924
382 MACROMOLECULE CATABOLIC PROCESS 13 926 0.0007745 0.009434
383 DNA RECOMBINATION 6 215 0.0007808 0.009485
384 POSITIVE REGULATION OF CYTOKINESIS 3 36 0.0007907 0.009532
385 POSITIVE REGULATION OF PROTEIN ACETYLATION 3 36 0.0007907 0.009532
386 REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 3 36 0.0007907 0.009532
387 IMMUNE SYSTEM PROCESS 21 1984 0.0008072 0.009705
388 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 5 144 0.0008212 0.009823
389 REGULATION OF PROTEIN COMPLEX DISASSEMBLY 6 217 0.0008193 0.009823
390 ORGAN REGENERATION 4 83 0.0008293 0.009894
391 REGULATION OF MITOCHONDRION ORGANIZATION 6 218 0.000839 0.009985
NumGOOverlapSizeP ValueAdj. P Value
1 PROTEIN KINASE ACTIVITY 30 640 3.626e-21 3.368e-18
2 PROTEIN SERINE THREONINE KINASE ACTIVITY 25 445 1.679e-19 7.801e-17
3 KINASE ACTIVITY 31 842 7.594e-19 2.352e-16
4 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 32 992 8.647e-18 2.008e-15
5 RIBONUCLEOTIDE BINDING 41 1860 4.319e-17 8.025e-15
6 ADENYL NUCLEOTIDE BINDING 35 1514 4.923e-15 7.623e-13
7 KINASE BINDING 22 606 2.682e-13 3.403e-11
8 ENZYME BINDING 35 1737 2.93e-13 3.403e-11
9 HISTONE KINASE ACTIVITY 6 19 3.671e-10 3.79e-08
10 PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 9 178 2.959e-07 2.749e-05
11 CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 5 34 7.363e-07 6.218e-05
12 PROTEIN TYROSINE PHOSPHATASE ACTIVITY 7 103 9.046e-07 7.003e-05
13 RNA BINDING 23 1598 3.584e-06 0.0002561
14 POLY A RNA BINDING 19 1170 5.419e-06 0.0003596
15 HEAT SHOCK PROTEIN BINDING 6 89 5.913e-06 0.0003662
16 PHOSPHATASE ACTIVITY 9 275 1.067e-05 0.0006198
17 PROTEIN TYROSINE KINASE ACTIVITY 7 176 3.111e-05 0.0017
18 STEROID HORMONE RECEPTOR BINDING 5 81 5.619e-05 0.0029
19 PROTEIN KINASE C ACTIVITY 3 16 6.674e-05 0.003013
20 TRANSCRIPTION FACTOR BINDING 11 524 6.811e-05 0.003013
21 MACROMOLECULAR COMPLEX BINDING 19 1399 6.507e-05 0.003013
22 PROTEIN DOMAIN SPECIFIC BINDING 12 624 7.253e-05 0.003063
23 NON MEMBRANE SPANNING PROTEIN TYROSINE KINASE ACTIVITY 4 46 8.494e-05 0.003431
24 PHOSPHORIC ESTER HYDROLASE ACTIVITY 9 368 0.0001033 0.003999
25 IDENTICAL PROTEIN BINDING 17 1209 0.0001098 0.004081
26 PROTEIN KINASE C BINDING 4 50 0.000118 0.004218
27 HISTONE DEACETYLASE BINDING 5 105 0.0001925 0.006622
NumGOOverlapSizeP ValueAdj. P Value
1 MICROTUBULE CYTOSKELETON 29 1068 3.708e-14 2.166e-11
2 NUCLEAR CHROMOSOME 20 523 1.464e-12 4.274e-10
3 CHROMOSOME 23 880 5.842e-11 1.137e-08
4 CHROMOSOMAL REGION 15 330 1.102e-10 1.609e-08
5 CYTOSKELETAL PART 28 1436 2.977e-10 2.173e-08
6 CYTOSKELETON 33 1967 2.437e-10 2.173e-08
7 CONDENSED CHROMOSOME 12 195 2.937e-10 2.173e-08
8 MICROTUBULE ORGANIZING CENTER 19 623 2.722e-10 2.173e-08
9 SPINDLE 13 289 2.399e-09 1.557e-07
10 CENTROSOME 16 487 2.855e-09 1.667e-07
11 CONDENSED NUCLEAR CHROMOSOME 8 85 1.115e-08 5.92e-07
12 CONDENSED CHROMOSOME CENTROMERIC REGION 8 102 4.736e-08 2.305e-06
13 CELL SUBSTRATE JUNCTION 13 398 1.058e-07 4.751e-06
14 KINETOCHORE 8 120 1.684e-07 7.026e-06
15 CHROMOSOME CENTROMERIC REGION 9 174 2.44e-07 8.963e-06
16 SPINDLE POLE 8 126 2.456e-07 8.963e-06
17 MIDBODY 8 132 3.512e-07 1.207e-05
18 ANCHORING JUNCTION 13 489 1.095e-06 3.554e-05
19 CONDENSED NUCLEAR CHROMOSOME CENTROMERIC REGION 4 18 1.775e-06 5.457e-05
20 CELL JUNCTION 19 1151 4.279e-06 0.000125
21 NUCLEOLUS 16 848 5.177e-06 0.000144
22 CHROMOSOME TELOMERIC REGION 7 162 1.825e-05 0.0004845
23 PERINUCLEAR REGION OF CYTOPLASM 13 642 2.078e-05 0.0005277
24 CONDENSED CHROMOSOME OUTER KINETOCHORE 3 12 2.661e-05 0.0006474
25 NUCLEAR CHROMOSOME TELOMERIC REGION 6 132 5.594e-05 0.001307
26 CELL DIVISION SITE 4 52 0.0001377 0.003093
27 MITOTIC SPINDLE 4 55 0.0001715 0.003709
28 SPINDLE MICROTUBULE 4 58 0.0002108 0.004397
29 SPINDLE MIDZONE 3 27 0.0003348 0.006742
30 HISTONE METHYLTRANSFERASE COMPLEX 4 71 0.0004592 0.008939

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04110_Cell_cycle 19 128 5.466e-23 9.839e-21
2 hsa04114_Oocyte_meiosis 12 114 5.073e-13 3.811e-11
3 hsa04914_Progesterone.mediated_oocyte_maturation 11 87 6.352e-13 3.811e-11
4 hsa04151_PI3K_AKT_signaling_pathway 13 351 2.441e-08 1.098e-06
5 hsa04810_Regulation_of_actin_cytoskeleton 10 214 1.312e-07 4.723e-06
6 hsa04370_VEGF_signaling_pathway 6 76 2.345e-06 7.036e-05
7 hsa04910_Insulin_signaling_pathway 7 138 6.406e-06 0.0001647
8 hsa04510_Focal_adhesion 8 200 7.932e-06 0.0001737
9 hsa04010_MAPK_signaling_pathway 9 268 8.683e-06 0.0001737
10 hsa04390_Hippo_signaling_pathway 7 154 1.314e-05 0.0002365
11 hsa04115_p53_signaling_pathway 5 69 2.586e-05 0.0004231
12 hsa04722_Neurotrophin_signaling_pathway 6 127 4.507e-05 0.0006761
13 hsa04360_Axon_guidance 6 130 5.137e-05 0.0007113
14 hsa04012_ErbB_signaling_pathway 5 87 7.912e-05 0.001017
15 hsa04540_Gap_junction 5 90 9.299e-05 0.001116
16 hsa04666_Fc_gamma_R.mediated_phagocytosis 5 95 0.0001202 0.001352
17 hsa04912_GnRH_signaling_pathway 5 101 0.0001604 0.001699
18 hsa04660_T_cell_receptor_signaling_pathway 5 108 0.0002196 0.002196
19 hsa04720_Long.term_potentiation 4 70 0.000435 0.004121
20 hsa04530_Tight_junction 5 133 0.0005732 0.005159
21 hsa04664_Fc_epsilon_RI_signaling_pathway 4 79 0.0006886 0.005902
22 hsa04014_Ras_signaling_pathway 6 236 0.001263 0.01033
23 hsa04150_mTOR_signaling_pathway 3 52 0.002309 0.01807
24 hsa04062_Chemokine_signaling_pathway 5 189 0.002722 0.02033
25 hsa04270_Vascular_smooth_muscle_contraction 4 116 0.002847 0.02033
26 hsa04670_Leukocyte_transendothelial_migration 4 117 0.002936 0.02033
27 hsa04620_Toll.like_receptor_signaling_pathway 3 102 0.01496 0.09976
28 hsa04144_Endocytosis 4 203 0.01961 0.126
29 hsa04330_Notch_signaling_pathway 2 47 0.02355 0.1462
30 hsa04621_NOD.like_receptor_signaling_pathway 2 59 0.03586 0.2151
31 hsa04730_Long.term_depression 2 70 0.04885 0.2836
32 hsa04520_Adherens_junction 2 73 0.05264 0.2914
33 hsa04141_Protein_processing_in_endoplasmic_reticulum 3 168 0.05343 0.2914
34 hsa04662_B_cell_receptor_signaling_pathway 2 75 0.05523 0.2924
35 hsa03008_Ribosome_biogenesis_in_eukaryotes 2 81 0.06326 0.3253
36 hsa04916_Melanogenesis 2 101 0.0925 0.45
37 hsa04380_Osteoclast_differentiation 2 128 0.1367 0.631
38 hsa04650_Natural_killer_cell_mediated_cytotoxicity 2 136 0.1506 0.6625
39 hsa04120_Ubiquitin_mediated_proteolysis 2 139 0.1558 0.6625
40 hsa04145_Phagosome 2 156 0.1863 0.7136

Quest ID: d76d8b0a0debfb15c11e78af074c58aa