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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-126-5p ABCA12 0.22 0.0501 -1.3 1.0E-5 mirMAP -0.27 0.01666 NA
2 hsa-miR-126-5p ABCB5 0.22 0.0501 0.03 0.9111 mirMAP -0.19 0.0485 NA
3 hsa-miR-126-5p ABCC9 0.22 0.0501 -1.23 0 mirMAP -0.14 0.04239 NA
4 hsa-miR-126-5p ABLIM1 0.22 0.0501 -0.73 0 mirMAP -0.14 0.00596 NA
5 hsa-miR-126-5p ACOT11 0.22 0.0501 -1.43 0 mirMAP -0.26 0.00012 NA
6 hsa-miR-126-5p AFF2 0.22 0.0501 -1.9 0 mirMAP; miRNATAP -0.19 0.02483 NA
7 hsa-miR-126-5p AGPAT4 0.22 0.0501 -0.67 0 mirMAP -0.15 0.00525 NA
8 hsa-miR-126-5p AGPS 0.22 0.0501 -0.88 0 mirMAP -0.12 0.00851 NA
9 hsa-miR-126-5p AJAP1 0.22 0.0501 -1.01 0 mirMAP -0.19 0.02137 NA
10 hsa-miR-126-5p ANGPTL1 0.22 0.0501 -1.94 0 mirMAP -0.19 0.04016 NA
11 hsa-miR-126-5p ANKDD1A 0.22 0.0501 -0.62 0 mirMAP -0.13 0.00215 NA
12 hsa-miR-126-5p ANKRD45 0.22 0.0501 -1.55 0 mirMAP -0.18 0.02109 NA
13 hsa-miR-126-5p ANP32E 0.22 0.0501 -1.17 0 mirMAP -0.12 0.00914 NA
14 hsa-miR-126-5p ANTXR2 0.22 0.0501 -0.69 0 MirTarget -0.13 0.0064 NA
15 hsa-miR-126-5p APLF 0.22 0.0501 -0.91 0 mirMAP -0.17 0.00035 NA
16 hsa-miR-126-5p ARHGAP20 0.22 0.0501 -1.96 0 mirMAP -0.2 0.00836 NA
17 hsa-miR-126-5p ARL4C 0.22 0.0501 -0.78 0 MirTarget; mirMAP; miRNATAP -0.15 0.00141 NA
18 hsa-miR-126-5p ARL6IP6 0.22 0.0501 -0.24 0.00097 mirMAP -0.11 5.0E-5 NA
19 hsa-miR-126-5p ARRDC3 0.22 0.0501 -0.49 2.0E-5 mirMAP -0.16 0.00013 NA
20 hsa-miR-126-5p ARSJ 0.22 0.0501 -1.03 0 mirMAP -0.3 0 NA
21 hsa-miR-126-5p ATCAY 0.22 0.0501 -1.63 0 mirMAP -0.39 4.0E-5 NA
22 hsa-miR-126-5p ATP1B1 0.22 0.0501 -1.17 0 mirMAP -0.19 0.00037 NA
23 hsa-miR-126-5p B4GALT6 0.22 0.0501 -0.82 0 mirMAP -0.16 0.00016 NA
24 hsa-miR-126-5p BCL11A 0.22 0.0501 -1.44 0 mirMAP -0.38 2.0E-5 NA
25 hsa-miR-126-5p BCL2 0.22 0.0501 -1.2 0 mirMAP -0.2 0.00033 NA
26 hsa-miR-126-5p BDH2 0.22 0.0501 -1.01 0 MirTarget -0.13 0.01144 NA
27 hsa-miR-126-5p BEND6 0.22 0.0501 -0.83 0 mirMAP -0.16 0.0018 NA
28 hsa-miR-126-5p BHLHE41 0.22 0.0501 -0.25 0.10102 mirMAP -0.14 0.01183 NA
29 hsa-miR-126-5p BNC2 0.22 0.0501 -1.29 0 mirMAP -0.16 0.01014 NA
30 hsa-miR-126-5p BVES 0.22 0.0501 -1.18 0 mirMAP -0.24 0.00055 NA
31 hsa-miR-126-5p C11orf45 0.22 0.0501 -1.74 0 miRNATAP -0.21 0.00181 NA
32 hsa-miR-126-5p C1D 0.22 0.0501 -0.11 0.12 mirMAP -0.16 0 NA
33 hsa-miR-126-5p C1RL 0.22 0.0501 -0.17 0.13006 MirTarget -0.17 4.0E-5 NA
34 hsa-miR-126-5p C2orf88 0.22 0.0501 -2.69 0 mirMAP -0.33 0.00015 NA
35 hsa-miR-126-5p C3orf58 0.22 0.0501 -0.39 6.0E-5 mirMAP -0.11 0.00392 NA
36 hsa-miR-126-5p C3orf70 0.22 0.0501 -1.44 0 mirMAP -0.25 9.0E-5 NA
37 hsa-miR-126-5p C9orf47 0.22 0.0501 -0.53 0.00074 mirMAP -0.19 0.0012 NA
38 hsa-miR-126-5p CACNB4 0.22 0.0501 -0.97 0 mirMAP -0.26 4.0E-5 NA
39 hsa-miR-126-5p CALD1 0.22 0.0501 -1.23 0 mirMAP -0.18 0.00025 NA
40 hsa-miR-126-5p CDCA7 0.22 0.0501 -0.62 0.00061 MirTarget; miRNATAP -0.32 0 NA
41 hsa-miR-126-5p CELF2 0.22 0.0501 -1.12 0 mirMAP; miRNATAP -0.13 0.0247 NA
42 hsa-miR-126-5p CFL2 0.22 0.0501 -1.33 0 MirTarget; mirMAP -0.14 0.00243 NA
43 hsa-miR-126-5p CHL1 0.22 0.0501 -0.41 0.12478 mirMAP -0.22 0.03355 NA
44 hsa-miR-126-5p CHODL 0.22 0.0501 -0.6 0.01606 mirMAP -0.36 0.00013 NA
45 hsa-miR-126-5p CHRDL1 0.22 0.0501 -2.13 0 mirMAP -0.31 0.00049 NA
46 hsa-miR-126-5p CLIP4 0.22 0.0501 -1.23 0 mirMAP -0.22 2.0E-5 NA
47 hsa-miR-126-5p CNTN1 0.22 0.0501 -1.78 0 MirTarget -0.22 0.04692 NA
48 hsa-miR-126-5p CNTNAP3 0.22 0.0501 -0.45 0.01716 mirMAP -0.16 0.02394 NA
49 hsa-miR-126-5p CRYZ 0.22 0.0501 -0.84 0 mirMAP -0.13 0.00014 NA
50 hsa-miR-126-5p CYP24A1 0.22 0.0501 -1.49 0.00015 mirMAP -0.46 0.00209 NA
51 hsa-miR-126-5p DAB1 0.22 0.0501 -2.75 0 mirMAP -0.43 0.0004 NA
52 hsa-miR-126-5p DACH2 0.22 0.0501 -1.01 0.0039 mirMAP -0.31 0.01929 NA
53 hsa-miR-126-5p DCBLD2 0.22 0.0501 -0.76 0 mirMAP -0.13 0.00027 NA
54 hsa-miR-126-5p DCDC2 0.22 0.0501 -0.24 0.3307 MirTarget; mirMAP; miRNATAP -0.19 0.04947 NA
55 hsa-miR-126-5p DMD 0.22 0.0501 -1.67 0 MirTarget; mirMAP -0.16 0.02432 NA
56 hsa-miR-126-5p DNAJB4 0.22 0.0501 -1.41 0 mirMAP -0.16 0.00576 NA
57 hsa-miR-126-5p DSG3 0.22 0.0501 -1.91 0 mirMAP -0.4 0.00329 NA
58 hsa-miR-126-5p DUSP19 0.22 0.0501 -1.15 0 mirMAP -0.16 7.0E-5 NA
59 hsa-miR-126-5p EDA2R 0.22 0.0501 -1.15 0 MirTarget -0.17 0.00739 NA
60 hsa-miR-126-5p EDAR 0.22 0.0501 -2.05 0 mirMAP -0.56 0 NA
61 hsa-miR-126-5p EDNRA 0.22 0.0501 -1.35 0 mirMAP -0.24 0.00011 NA
62 hsa-miR-126-5p EPHA3 0.22 0.0501 -0.73 8.0E-5 mirMAP -0.15 0.03152 NA
63 hsa-miR-126-5p EPHA5 0.22 0.0501 -1.46 1.0E-5 mirMAP -0.32 0.00776 NA
64 hsa-miR-126-5p EPHA7 0.22 0.0501 -0.61 0.00129 mirMAP; miRNATAP -0.3 2.0E-5 NA
65 hsa-miR-126-5p EPHB1 0.22 0.0501 -2.38 0 MirTarget -0.2 0.03078 NA
66 hsa-miR-126-5p ERAP1 0.22 0.0501 -0.61 0 mirMAP -0.11 0.00385 NA
67 hsa-miR-126-5p ESRRG 0.22 0.0501 0.13 0.45469 MirTarget; miRNATAP -0.22 0.0011 NA
68 hsa-miR-126-5p ETV1 0.22 0.0501 -0.29 0.28668 MirTarget; mirMAP -0.22 0.03104 NA
69 hsa-miR-126-5p EXPH5 0.22 0.0501 -0.02 0.82932 mirMAP -0.17 6.0E-5 NA
70 hsa-miR-126-5p EYA1 0.22 0.0501 -1.09 0 mirMAP; miRNATAP -0.25 0.00203 NA
71 hsa-miR-126-5p EYA4 0.22 0.0501 -1.86 0 MirTarget; mirMAP -0.3 0.00018 NA
72 hsa-miR-126-5p FABP3 0.22 0.0501 -1.17 0 MirTarget -0.2 0.00477 NA
73 hsa-miR-126-5p FAM172A 0.22 0.0501 -0.31 4.0E-5 mirMAP -0.1 0.00021 NA
74 hsa-miR-126-5p FAM19A2 0.22 0.0501 -1.32 0 MirTarget; mirMAP -0.25 0.00021 NA
75 hsa-miR-126-5p FAM81A 0.22 0.0501 0.3 0.11208 mirMAP -0.14 0.04949 NA
76 hsa-miR-126-5p FAT3 0.22 0.0501 -2.27 0 mirMAP; miRNATAP -0.34 0.00037 NA
77 hsa-miR-126-5p FBN2 0.22 0.0501 -1.04 0 mirMAP -0.28 0.00106 NA
78 hsa-miR-126-5p FGF1 0.22 0.0501 -0.64 0.00026 mirMAP -0.2 0.00253 NA
79 hsa-miR-126-5p FGF2 0.22 0.0501 -1.33 0 mirMAP -0.2 0.0019 NA
80 hsa-miR-126-5p FGF7 0.22 0.0501 -1.48 0 miRNATAP -0.32 0 NA
81 hsa-miR-126-5p FGFR2 0.22 0.0501 -1.97 0 mirMAP; miRNATAP -0.32 0.00017 NA
82 hsa-miR-126-5p FMO2 0.22 0.0501 -1.23 0 mirMAP -0.23 0.00716 NA
83 hsa-miR-126-5p FOXF1 0.22 0.0501 -1.02 0 mirMAP -0.18 0.00444 NA
84 hsa-miR-126-5p FOXP2 0.22 0.0501 -1.86 0 miRNATAP -0.21 0.03037 NA
85 hsa-miR-126-5p FRMPD4 0.22 0.0501 -1.15 0.00023 mirMAP -0.34 0.00356 NA
86 hsa-miR-126-5p GATA3 0.22 0.0501 -2.36 0 MirTarget -0.39 4.0E-5 NA
87 hsa-miR-126-5p GATM 0.22 0.0501 -1.64 0 mirMAP -0.27 1.0E-5 NA
88 hsa-miR-126-5p GCG 0.22 0.0501 0.71 0.03988 mirMAP -0.43 0.00085 NA
89 hsa-miR-126-5p GDA 0.22 0.0501 0.33 0.49241 mirMAP -0.36 0.04811 NA
90 hsa-miR-126-5p GNAL 0.22 0.0501 -1.99 0 mirMAP -0.22 0.00422 NA
91 hsa-miR-126-5p GRAMD1C 0.22 0.0501 -0.07 0.59828 mirMAP -0.13 0.0077 NA
92 hsa-miR-126-5p GRIA2 0.22 0.0501 -1.33 0 mirMAP; miRNATAP -0.22 0.02514 NA
93 hsa-miR-126-5p GRIN2A 0.22 0.0501 -1.72 0 mirMAP -0.22 0.02072 NA
94 hsa-miR-126-5p HECTD2 0.22 0.0501 -0.96 0 mirMAP -0.12 0.00436 NA
95 hsa-miR-126-5p HFE 0.22 0.0501 -1.82 0 mirMAP -0.2 0.00869 NA
96 hsa-miR-126-5p HHIP 0.22 0.0501 -0.77 0.00198 mirMAP -0.38 6.0E-5 NA
97 hsa-miR-126-5p HLF 0.22 0.0501 -1.26 0 mirMAP -0.24 5.0E-5 NA
98 hsa-miR-126-5p HMGCLL1 0.22 0.0501 -2.16 0 mirMAP -0.22 0.0323 NA
99 hsa-miR-126-5p HOXB2 0.22 0.0501 -1.41 0 miRNATAP -0.17 0.0057 NA
100 hsa-miR-126-5p HOXD13 0.22 0.0501 -2.21 0 mirMAP -0.48 0 NA
101 hsa-miR-126-5p HSPA4L 0.22 0.0501 -1.92 0 mirMAP -0.17 0.02671 NA
102 hsa-miR-126-5p HSPB8 0.22 0.0501 -2.17 0 MirTarget; miRNATAP -0.34 5.0E-5 NA
103 hsa-miR-126-5p IGSF1 0.22 0.0501 -3.07 0 mirMAP -0.37 0.00278 NA
104 hsa-miR-126-5p IKZF2 0.22 0.0501 -0.39 0.00051 MirTarget; mirMAP; miRNATAP -0.18 1.0E-5 NA
105 hsa-miR-126-5p ITGA2 0.22 0.0501 -1.46 0 mirMAP -0.19 0.00316 NA
106 hsa-miR-126-5p ITGB6 0.22 0.0501 -1.85 0 MirTarget -0.37 0.00012 NA
107 hsa-miR-126-5p ITM2B 0.22 0.0501 -0.6 0 mirMAP -0.11 0.00014 NA
108 hsa-miR-126-5p JAZF1 0.22 0.0501 -1.34 0 mirMAP -0.19 0.00034 NA
109 hsa-miR-126-5p KATNAL1 0.22 0.0501 -1.06 0 mirMAP -0.12 0.0044 NA
110 hsa-miR-126-5p KCNJ3 0.22 0.0501 -2.97 0 mirMAP -0.25 0.04607 NA
111 hsa-miR-126-5p KCNQ5 0.22 0.0501 -1.81 0 mirMAP -0.25 0.00161 NA
112 hsa-miR-126-5p KDELC2 0.22 0.0501 -0.73 0 MirTarget; mirMAP -0.18 0 NA
113 hsa-miR-126-5p KIAA1644 0.22 0.0501 -1.65 0 MirTarget -0.36 2.0E-5 NA
114 hsa-miR-126-5p KITLG 0.22 0.0501 -1.39 0 mirMAP -0.13 0.01371 NA
115 hsa-miR-126-5p KLF8 0.22 0.0501 -1.17 0 mirMAP -0.1 0.04743 NA
116 hsa-miR-126-5p L3MBTL4 0.22 0.0501 -2.01 0 mirMAP -0.31 2.0E-5 NA
117 hsa-miR-126-5p LMO3 0.22 0.0501 -2 0 mirMAP -0.19 0.01938 NA
118 hsa-miR-126-5p LONRF3 0.22 0.0501 -1.79 0 MirTarget -0.17 0.03121 NA
119 hsa-miR-126-5p LRAT 0.22 0.0501 -1.39 1.0E-5 mirMAP -0.36 0.00282 NA
120 hsa-miR-126-5p LRCH2 0.22 0.0501 -1.55 0 MirTarget; mirMAP; miRNATAP -0.33 1.0E-5 NA
121 hsa-miR-126-5p LRP1B 0.22 0.0501 -2.22 0 mirMAP -0.27 0.00652 NA
122 hsa-miR-126-5p LSM11 0.22 0.0501 -0.71 0 mirMAP -0.11 0.00061 NA
123 hsa-miR-126-5p MACC1 0.22 0.0501 -1.42 0 MirTarget; mirMAP; miRNATAP -0.33 4.0E-5 NA
124 hsa-miR-126-5p MAT2B 0.22 0.0501 -0.68 0 MirTarget; miRNATAP -0.11 0 NA
125 hsa-miR-126-5p MBNL2 0.22 0.0501 -1.17 0 mirMAP -0.17 0.00034 NA
126 hsa-miR-126-5p MCC 0.22 0.0501 -1.58 0 mirMAP -0.19 0.00208 NA
127 hsa-miR-126-5p MDFIC 0.22 0.0501 -1.01 0 mirMAP -0.15 0.0017 NA
128 hsa-miR-126-5p METTL7A 0.22 0.0501 -1.14 0 mirMAP -0.13 0.00617 NA
129 hsa-miR-126-5p MITF 0.22 0.0501 -0.77 0 MirTarget; mirMAP -0.1 0.01497 NA
130 hsa-miR-126-5p MMP7 0.22 0.0501 -0.03 0.93155 miRNAWalker2 validate -0.42 0.0002 NA
131 hsa-miR-126-5p MPPED2 0.22 0.0501 -0.6 0.00023 mirMAP -0.16 0.01011 NA
132 hsa-miR-126-5p MR1 0.22 0.0501 -1.24 0 MirTarget -0.21 9.0E-5 NA
133 hsa-miR-126-5p MYLK 0.22 0.0501 -2.13 0 mirMAP -0.34 2.0E-5 NA
134 hsa-miR-126-5p N4BP2L1 0.22 0.0501 -0.5 3.0E-5 mirMAP -0.16 0.00048 NA
135 hsa-miR-126-5p NAV3 0.22 0.0501 -0.97 0 mirMAP -0.2 0.00248 NA
136 hsa-miR-126-5p NEBL 0.22 0.0501 -0.52 0 mirMAP -0.2 0 NA
137 hsa-miR-126-5p NECAB1 0.22 0.0501 -1.96 0 MirTarget; mirMAP -0.38 0 NA
138 hsa-miR-126-5p NEGR1 0.22 0.0501 -1.09 0 mirMAP -0.19 0.00513 NA
139 hsa-miR-126-5p NHS 0.22 0.0501 -1.46 0 mirMAP -0.2 0.00048 NA
140 hsa-miR-126-5p NNT 0.22 0.0501 -0.91 0 mirMAP -0.13 0.0018 NA
141 hsa-miR-126-5p NOG 0.22 0.0501 -1.25 0 mirMAP; miRNATAP -0.23 0.00208 NA
142 hsa-miR-126-5p NR1D2 0.22 0.0501 -0.35 8.0E-5 mirMAP -0.11 0.00075 NA
143 hsa-miR-126-5p NRK 0.22 0.0501 -1.83 0 mirMAP -0.29 0.00232 NA
144 hsa-miR-126-5p NRXN1 0.22 0.0501 -1.77 0 mirMAP -0.27 0.00423 NA
145 hsa-miR-126-5p NRXN3 0.22 0.0501 -1.56 0 mirMAP -0.22 0.00152 NA
146 hsa-miR-126-5p NT5E 0.22 0.0501 -1.44 0 mirMAP -0.18 0.00525 NA
147 hsa-miR-126-5p OGN 0.22 0.0501 -1.28 0 mirMAP -0.28 0.00052 NA
148 hsa-miR-126-5p OSBPL10 0.22 0.0501 -0.28 0.01145 mirMAP -0.13 0.0021 NA
149 hsa-miR-126-5p PABPC4L 0.22 0.0501 -1.11 0 mirMAP -0.25 1.0E-5 NA
150 hsa-miR-126-5p PAQR8 0.22 0.0501 -1.73 0 mirMAP -0.21 0.00117 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 MORPHOGENESIS OF A BRANCHING STRUCTURE 19 167 1.567e-13 7.289e-10
2 TISSUE DEVELOPMENT 51 1518 1.289e-11 2.998e-08
3 GLAND MORPHOGENESIS 13 97 1.477e-10 2.29e-07
4 TISSUE MORPHOGENESIS 27 533 3.08e-10 3.583e-07
5 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 51 1672 4.118e-10 3.832e-07
6 MORPHOGENESIS OF AN EPITHELIUM 23 400 6.116e-10 4.065e-07
7 ORGAN MORPHOGENESIS 34 841 5.379e-10 4.065e-07
8 TUBE DEVELOPMENT 26 552 3.102e-09 1.804e-06
9 MESENCHYME DEVELOPMENT 15 190 1.018e-08 5.265e-06
10 GLAND DEVELOPMENT 21 395 1.398e-08 6.503e-06
11 EPITHELIUM DEVELOPMENT 33 945 3.561e-08 1.506e-05
12 NEURON PROJECTION DEVELOPMENT 24 545 4.664e-08 1.808e-05
13 REGULATION OF EPITHELIAL CELL PROLIFERATION 17 285 6.793e-08 2.282e-05
14 MESENCHYMAL CELL DIFFERENTIATION 12 134 7.847e-08 2.282e-05
15 TUBE MORPHOGENESIS 18 323 7.76e-08 2.282e-05
16 STEM CELL DIFFERENTIATION 14 190 7.604e-08 2.282e-05
17 SALIVARY GLAND DEVELOPMENT 7 32 8.558e-08 2.342e-05
18 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 28 750 1.096e-07 2.683e-05
19 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 36 1142 1.046e-07 2.683e-05
20 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 32 957 1.573e-07 3.66e-05
21 NEURON PROJECTION GUIDANCE 14 205 1.95e-07 4.32e-05
22 NEUROGENESIS 40 1402 2.646e-07 5.596e-05
23 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 18 368 5.345e-07 0.0001036
24 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 11 131 5.29e-07 0.0001036
25 LUNG MORPHOGENESIS 7 45 1.01e-06 0.0001786
26 EXOCRINE SYSTEM DEVELOPMENT 7 45 1.01e-06 0.0001786
27 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 21 513 1.097e-06 0.0001786
28 REGULATION OF STEM CELL PROLIFERATION 9 88 1.113e-06 0.0001786
29 CELL DEVELOPMENT 39 1426 1.101e-06 0.0001786
30 BRANCH ELONGATION OF AN EPITHELIUM 5 17 1.313e-06 0.0001971
31 REGULATION OF CELL DIFFERENTIATION 40 1492 1.293e-06 0.0001971
32 REGULATION OF ORGAN MORPHOGENESIS 14 242 1.443e-06 0.0002099
33 ORGAN GROWTH 8 68 1.521e-06 0.0002145
34 NEURON PROJECTION MORPHOGENESIS 18 402 1.895e-06 0.0002594
35 BLOOD VESSEL MORPHOGENESIS 17 364 2.092e-06 0.0002782
36 BIOLOGICAL ADHESION 31 1032 2.429e-06 0.000314
37 NEURON DEVELOPMENT 24 687 2.988e-06 0.0003733
38 MESONEPHRIC TUBULE MORPHOGENESIS 7 53 3.163e-06 0.0003733
39 CARDIOVASCULAR SYSTEM DEVELOPMENT 26 788 3.209e-06 0.0003733
40 CIRCULATORY SYSTEM DEVELOPMENT 26 788 3.209e-06 0.0003733
41 REGULATION OF NEURON DIFFERENTIATION 21 554 3.68e-06 0.0004177
42 VASCULATURE DEVELOPMENT 19 469 4.22e-06 0.0004566
43 CELL PROJECTION ORGANIZATION 28 902 4.209e-06 0.0004566
44 RESPIRATORY SYSTEM DEVELOPMENT 12 197 4.858e-06 0.0005137
45 MUSCLE TISSUE DEVELOPMENT 14 275 6.386e-06 0.0006603
46 PROSTATE GLAND MORPHOGENESIS 5 23 6.731e-06 0.0006809
47 NEURON DIFFERENTIATION 27 874 6.91e-06 0.0006841
48 POSITIVE REGULATION OF STEM CELL PROLIFERATION 7 61 8.252e-06 0.0007999
49 PROSTATE GLAND DEVELOPMENT 6 41 8.874e-06 0.0008427
50 REGULATION OF CELL DEVELOPMENT 26 836 9.196e-06 0.0008557
51 SKIN DEVELOPMENT 12 211 9.778e-06 0.0008921
52 EPITHELIAL TUBE BRANCHING INVOLVED IN LUNG MORPHOGENESIS 5 25 1.042e-05 0.0008981
53 REGULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 5 25 1.042e-05 0.0008981
54 GROWTH 17 410 1.014e-05 0.0008981
55 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 36 1395 1.101e-05 0.0009313
56 DIGESTIVE SYSTEM DEVELOPMENT 10 148 1.231e-05 0.00102
57 NEGATIVE REGULATION OF AXONOGENESIS 7 65 1.264e-05 0.00102
58 MESONEPHROS DEVELOPMENT 8 90 1.272e-05 0.00102
59 DEVELOPMENTAL GROWTH 15 333 1.295e-05 0.001021
60 POSITIVE REGULATION OF LOCOMOTION 17 420 1.384e-05 0.001073
61 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 29 1021 1.524e-05 0.001147
62 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 5 27 1.553e-05 0.001147
63 AXIS ELONGATION 5 27 1.553e-05 0.001147
64 UROGENITAL SYSTEM DEVELOPMENT 14 299 1.643e-05 0.001194
65 KIDNEY EPITHELIUM DEVELOPMENT 9 125 2.029e-05 0.001453
66 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 12 229 2.217e-05 0.001545
67 EPIDERMIS MORPHOGENESIS 5 29 2.24e-05 0.001545
68 DIGESTIVE TRACT MORPHOGENESIS 6 48 2.258e-05 0.001545
69 MORPHOGENESIS OF AN EPITHELIAL FOLD 4 15 2.488e-05 0.001678
70 CELLULAR COMPONENT MORPHOGENESIS 26 900 3.264e-05 0.002154
71 BRANCHING INVOLVED IN SALIVARY GLAND MORPHOGENESIS 4 16 3.286e-05 0.002154
72 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 34 1360 3.793e-05 0.002451
73 RENAL TUBULE DEVELOPMENT 7 78 4.204e-05 0.00268
74 POSITIVE REGULATION OF CELL PROLIFERATION 24 814 4.847e-05 0.003022
75 TAXIS 17 464 4.871e-05 0.003022
76 REGULATION OF MESENCHYMAL CELL PROLIFERATION 5 34 4.998e-05 0.00306
77 EPIDERMIS DEVELOPMENT 12 253 5.858e-05 0.003495
78 KIDNEY MORPHOGENESIS 7 82 5.809e-05 0.003495
79 MUSCLE CELL PROLIFERATION 4 19 6.803e-05 0.003957
80 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 7 84 6.782e-05 0.003957
81 LOCOMOTION 29 1114 7.369e-05 0.004233
82 EMBRYO DEVELOPMENT 25 894 7.852e-05 0.004456
83 NEGATIVE REGULATION OF CELL DEVELOPMENT 13 303 8.061e-05 0.004465
84 RESPONSE TO FIBROBLAST GROWTH FACTOR 8 116 7.979e-05 0.004465
85 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 16 437 8.198e-05 0.004488
86 CELL PART MORPHOGENESIS 20 633 8.372e-05 0.004529
87 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 8 117 8.478e-05 0.004534
88 EMBRYONIC MORPHOGENESIS 18 539 9.579e-05 0.005065
89 REGULATION OF SMOOTHENED SIGNALING PATHWAY 6 62 9.834e-05 0.005141
90 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 9 154 0.000104 0.005376
91 REGULATION OF CELL PROLIFERATION 35 1496 0.0001094 0.005594
92 EMBRYONIC ORGAN DEVELOPMENT 15 406 0.0001239 0.006223
93 LUNG ALVEOLUS DEVELOPMENT 5 41 0.0001257 0.006223
94 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 12 274 0.0001249 0.006223
95 SKELETAL SYSTEM DEVELOPMENT 16 455 0.0001307 0.006271
96 NEPHRON EPITHELIUM DEVELOPMENT 7 93 0.0001295 0.006271
97 REGULATION OF NEURON PROJECTION DEVELOPMENT 15 408 0.0001307 0.006271
98 AUTONOMIC NERVOUS SYSTEM DEVELOPMENT 5 42 0.0001413 0.00671
99 REGULATION OF CELL PROJECTION ORGANIZATION 18 558 0.0001475 0.00688
100 EMBRYONIC ORGAN MORPHOGENESIS 12 279 0.0001479 0.00688
101 POSITIVE REGULATION OF CELL DIFFERENTIATION 23 823 0.0001548 0.00713
102 REGULATION OF CELLULAR COMPONENT MOVEMENT 22 771 0.0001613 0.007358
103 BRANCHING INVOLVED IN URETERIC BUD MORPHOGENESIS 5 44 0.0001769 0.007957
104 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 39 1784 0.0001779 0.007957
105 REGULATION OF EPITHELIAL CELL MIGRATION 9 166 0.0001837 0.008139
106 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 26 1004 0.0001928 0.008465
107 REGULATION OF DEVELOPMENTAL GROWTH 12 289 0.0002049 0.008827
108 POSITIVE REGULATION OF GENE EXPRESSION 38 1733 0.0002049 0.008827
109 SKIN EPIDERMIS DEVELOPMENT 6 71 0.0002094 0.008941
110 NEGATIVE REGULATION OF CELL GROWTH 9 170 0.0002195 0.009285
111 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 39 1805 0.000226 0.009474
112 ANGIOGENESIS 12 293 0.0002324 0.009656
113 MUSCLE STRUCTURE DEVELOPMENT 15 432 0.0002426 0.009989
NumGOOverlapSizeP ValueAdj. P Value
1 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 24 629 6.407e-07 0.0005952
2 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 15 328 1.082e-05 0.005028
3 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 32 1199 1.859e-05 0.005758
4 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 10 168 3.684e-05 0.006085
5 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 14 315 2.924e-05 0.006085
6 GLYCOSAMINOGLYCAN BINDING 11 205 3.93e-05 0.006085
7 SEQUENCE SPECIFIC DNA BINDING 28 1037 5.285e-05 0.007014
8 EPHRIN RECEPTOR ACTIVITY 4 19 6.803e-05 0.0079
NumGOOverlapSizeP ValueAdj. P Value

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Regulation_of_actin_cytoskeleton_hsa04810 8 208 0.003727 0.1288
2 cAMP_signaling_pathway_hsa04024 7 198 0.01012 0.1288
3 PI3K_Akt_signaling_pathway_hsa04151 10 352 0.01035 0.1288
4 Hippo_signaling_pathway_hsa04390 6 154 0.01082 0.1288
5 Rap1_signaling_pathway_hsa04015 7 206 0.01239 0.1288
6 ABC_transporters_hsa02010 3 45 0.01672 0.1316
7 Hedgehog_signaling_pathway_hsa04340 3 47 0.01878 0.1316
8 Ras_signaling_pathway_hsa04014 7 232 0.02226 0.1316
9 Calcium_signaling_pathway_hsa04020 6 182 0.02278 0.1316
10 MAPK_signaling_pathway_hsa04010 8 295 0.02647 0.1377
11 ECM_receptor_interaction_hsa04512 3 82 0.07589 0.3383
12 Peroxisome_hsa04146 3 83 0.07807 0.3383
13 Focal_adhesion_hsa04510 5 199 0.09215 0.3617
14 Cell_adhesion_molecules_.CAMs._hsa04514 4 145 0.09738 0.3617
15 Tight_junction_hsa04530 4 170 0.1483 0.5142
16 Sphingolipid_signaling_pathway_hsa04071 3 118 0.1691 0.5443
17 AMPK_signaling_pathway_hsa04152 3 121 0.178 0.5443
18 FoxO_signaling_pathway_hsa04068 3 132 0.2115 0.6002
19 Apelin_signaling_pathway_hsa04371 3 137 0.2272 0.6002
20 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 3 139 0.2335 0.6002
21 Neuroactive_ligand_receptor_interaction_hsa04080 5 278 0.2424 0.6002
22 TGF_beta_signaling_pathway_hsa04350 2 84 0.2672 0.6315
23 Gap_junction_hsa04540 2 88 0.285 0.6404
24 cGMP_PKG_signaling_pathway_hsa04022 3 163 0.3113 0.6475
25 Cytokine_cytokine_receptor_interaction_hsa04060 4 270 0.407 0.7559
26 Oocyte_meiosis_hsa04114 2 124 0.4396 0.7883
27 Autophagy_animal_hsa04140 2 128 0.4558 0.79
28 Phospholipase_D_signaling_pathway_hsa04072 2 146 0.5249 0.8133
29 Wnt_signaling_pathway_hsa04310 2 146 0.5249 0.8133
30 Phagosome_hsa04145 2 152 0.5466 0.8133
31 Endocytosis_hsa04144 3 244 0.5631 0.8133

Quest ID: d98aca336f394825b998ecb5dfea9465