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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-21-5p AKT2 1.75 0 -0.01 0.9227 miRNAWalker2 validate -0.15 0.00352 NA
2 hsa-miR-29b-3p AKT2 -0.23 0.36746 -0.01 0.9227 MirTarget -0.14 0.00022 26512921; 26564501; 24076586 MicroRNA 29B mir 29b regulates the Warburg effect in ovarian cancer by targeting AKT2 and AKT3;The expression of miR-29b was significantly upregualted by cisplatin treatmentwhile its target gene AKT2 was downregulated;Furthermore a feed-back loop comprising of c-Myc miR-29 family and Akt2 were found in myeloid leukemogenesis
3 hsa-miR-106b-5p AKT3 1.71 0 -0.75 0.06936 miRNATAP -0.37 7.0E-5 NA
4 hsa-miR-107 AKT3 0.9 5.0E-5 -0.75 0.06936 PITA; miRanda -0.6 0 NA
5 hsa-miR-15b-5p AKT3 1.62 0 -0.75 0.06936 miRNATAP -0.36 0.00041 NA
6 hsa-miR-16-5p AKT3 1.01 1.0E-5 -0.75 0.06936 miRNAWalker2 validate; miRTarBase; miRNATAP -0.47 0.00031 NA
7 hsa-miR-17-3p AKT3 1.31 0 -0.75 0.06936 miRNATAP -0.52 0 NA
8 hsa-miR-17-5p AKT3 1.66 0 -0.75 0.06936 TargetScan; miRNATAP -0.28 0.0027 NA
9 hsa-miR-29a-3p AKT3 -0.11 0.61501 -0.75 0.06936 miRNATAP -0.41 0.00212 NA
10 hsa-miR-29b-3p AKT3 -0.23 0.36746 -0.75 0.06936 miRNATAP -0.34 0.00361 26512921 MicroRNA 29B mir 29b regulates the Warburg effect in ovarian cancer by targeting AKT2 and AKT3
11 hsa-miR-32-3p AKT3 0.58 0.11837 -0.75 0.06936 mirMAP -0.32 0.00023 NA
12 hsa-miR-320b AKT3 1.11 0.0005 -0.75 0.06936 PITA; miRanda; miRNATAP -0.26 0.0039 NA
13 hsa-miR-335-3p AKT3 2.52 0 -0.75 0.06936 mirMAP -0.22 0.00074 NA
14 hsa-miR-33a-3p AKT3 0.35 0.32171 -0.75 0.06936 mirMAP -0.38 2.0E-5 NA
15 hsa-miR-362-3p AKT3 -0.03 0.91378 -0.75 0.06936 miRanda -0.38 4.0E-5 NA
16 hsa-miR-362-5p AKT3 -0.35 0.35491 -0.75 0.06936 PITA; TargetScan; miRNATAP -0.23 0.00253 NA
17 hsa-miR-501-3p AKT3 0.73 0.02704 -0.75 0.06936 miRNATAP -0.39 1.0E-5 NA
18 hsa-miR-502-3p AKT3 -0.16 0.55747 -0.75 0.06936 miRNATAP -0.5 0 NA
19 hsa-miR-505-3p AKT3 0.83 0.00112 -0.75 0.06936 mirMAP -0.35 0.00235 22051041 We also find that Akt3 correlate inversely with miR-505 modulates drug sensitivity in MCF7-ADR
20 hsa-miR-548v AKT3 -0.16 0.70867 -0.75 0.06936 miRNATAP -0.27 0.00031 NA
21 hsa-miR-577 AKT3 0.91 0.22561 -0.75 0.06936 mirMAP -0.23 0 NA
22 hsa-miR-616-5p AKT3 0.83 0.03478 -0.75 0.06936 mirMAP -0.27 0.00041 NA
23 hsa-miR-125b-5p ARRB1 -0.51 0.13327 -1.74 0.0001 MirTarget -0.27 0.00426 NA
24 hsa-miR-149-5p ARRB1 0.71 0.29685 -1.74 0.0001 MirTarget -0.46 0 NA
25 hsa-miR-185-3p ARRB1 1.34 3.0E-5 -1.74 0.0001 MirTarget -0.3 0.00212 NA
26 hsa-miR-22-3p ARRB1 0.03 0.84509 -1.74 0.0001 MirTarget -1.09 0 NA
27 hsa-miR-296-5p ARRB1 0.93 0.06024 -1.74 0.0001 MirTarget; miRNATAP -0.42 0 NA
28 hsa-miR-324-3p ARRB1 1.05 0.00039 -1.74 0.0001 MirTarget -0.51 0 NA
29 hsa-miR-331-3p ARRB1 1.05 0.0001 -1.74 0.0001 MirTarget; miRNATAP -0.55 0 NA
30 hsa-miR-455-3p ARRB1 2.3 0 -1.74 0.0001 MirTarget -0.46 0 NA
31 hsa-miR-671-5p ARRB1 0.95 0.00247 -1.74 0.0001 MirTarget -0.37 0.00029 NA
32 hsa-miR-149-5p ARRB2 0.71 0.29685 0.08 0.6689 miRNAWalker2 validate -0.14 0 NA
33 hsa-miR-199a-5p ARRB2 0.37 0.23266 0.08 0.6689 MirTarget; miRanda -0.16 0.00021 NA
34 hsa-miR-199b-5p ARRB2 0.12 0.67816 0.08 0.6689 MirTarget; miRanda; miRNATAP -0.16 0.00037 NA
35 hsa-miR-365a-3p ARRB2 -0.89 0.00255 0.08 0.6689 MirTarget; miRNATAP -0.25 0 NA
36 hsa-miR-10b-5p ATF2 -0.3 0.31239 -0.02 0.89844 MirTarget; miRNATAP -0.13 0.00068 NA
37 hsa-miR-126-5p ATF2 0.42 0.07532 -0.02 0.89844 mirMAP -0.15 0.00299 NA
38 hsa-miR-212-3p ATF2 0.96 0.00133 -0.02 0.89844 miRNATAP -0.14 0.00026 NA
39 hsa-miR-590-3p ATF2 1.12 0.00016 -0.02 0.89844 MirTarget; miRanda; mirMAP; miRNATAP -0.12 0.00263 NA
40 hsa-miR-192-3p BDNF 0.36 0.74117 0.74 0.18381 MirTarget; miRNATAP -0.11 0.00424 NA
41 hsa-miR-29b-2-5p BDNF -1.7 0 0.74 0.18381 mirMAP -0.38 0.00762 NA
42 hsa-miR-338-5p BDNF -1.2 0.01003 0.74 0.18381 miRNATAP -0.3 0.00033 NA
43 hsa-miR-27b-3p CACNA1A 0.08 0.72527 -0.24 0.66624 MirTarget -0.47 0.00464 NA
44 hsa-miR-107 CACNA1B 0.9 5.0E-5 0.22 0.84313 miRanda -1.33 0.00013 NA
45 hsa-miR-140-3p CACNA1B -0.3 0.12754 0.22 0.84313 MirTarget; miRNATAP -2.3 0 NA
46 hsa-miR-200a-3p CACNA1B 0.72 0.19391 0.22 0.84313 mirMAP -0.48 0.0006 NA
47 hsa-miR-335-5p CACNA1B 1.6 6.0E-5 0.22 0.84313 miRNAWalker2 validate -0.71 0.00018 NA
48 hsa-miR-3614-5p CACNA1B 1.1 0.00706 0.22 0.84313 mirMAP; miRNATAP -1.16 0 NA
49 hsa-miR-362-3p CACNA1B -0.03 0.91378 0.22 0.84313 MirTarget; miRNATAP -0.87 0.00033 NA
50 hsa-miR-429 CACNA1B 1.4 0.009 0.22 0.84313 miRNATAP -0.46 0.00145 NA
51 hsa-miR-7-1-3p CACNA1B 0.71 0.04123 0.22 0.84313 MirTarget -1.03 0 NA
52 hsa-let-7a-3p CACNA1C 0.5 0.04111 -1.47 0.0005 MirTarget -0.59 0 NA
53 hsa-let-7b-3p CACNA1C 0.22 0.29604 -1.47 0.0005 MirTarget -0.51 0.00059 NA
54 hsa-let-7f-1-3p CACNA1C 1.29 0 -1.47 0.0005 MirTarget -0.44 7.0E-5 NA
55 hsa-miR-107 CACNA1C 0.9 5.0E-5 -1.47 0.0005 miRNATAP -0.52 0.00014 NA
56 hsa-miR-1254 CACNA1C 0.94 0.06055 -1.47 0.0005 PITA; miRNATAP -0.41 0 NA
57 hsa-miR-1271-5p CACNA1C 1.16 0.00208 -1.47 0.0005 MirTarget -0.27 0.00098 NA
58 hsa-miR-148b-5p CACNA1C 1.04 0.00196 -1.47 0.0005 mirMAP -0.34 0.00011 NA
59 hsa-miR-149-5p CACNA1C 0.71 0.29685 -1.47 0.0005 MirTarget -0.17 8.0E-5 NA
60 hsa-miR-186-5p CACNA1C 0.15 0.43471 -1.47 0.0005 mirMAP -0.63 9.0E-5 NA
61 hsa-miR-1976 CACNA1C 0.92 0.00012 -1.47 0.0005 MirTarget -0.56 1.0E-5 NA
62 hsa-miR-19a-3p CACNA1C 1.27 0.00011 -1.47 0.0005 MirTarget -0.5 0 NA
63 hsa-miR-19b-1-5p CACNA1C 1.39 0 -1.47 0.0005 MirTarget -0.55 0 NA
64 hsa-miR-19b-3p CACNA1C 0.76 0.00653 -1.47 0.0005 MirTarget -0.59 0 NA
65 hsa-miR-200b-3p CACNA1C 0.97 0.0595 -1.47 0.0005 MirTarget; TargetScan -0.22 0.00019 NA
66 hsa-miR-200c-3p CACNA1C 1.28 0.0037 -1.47 0.0005 MirTarget -0.41 0 NA
67 hsa-miR-26b-5p CACNA1C -0.3 0.16008 -1.47 0.0005 MirTarget; miRNATAP -0.5 0.00056 NA
68 hsa-miR-320a CACNA1C 0.59 0.0119 -1.47 0.0005 miRNATAP -0.4 0.00196 NA
69 hsa-miR-320b CACNA1C 1.11 0.0005 -1.47 0.0005 miRNATAP -0.41 1.0E-5 NA
70 hsa-miR-330-5p CACNA1C 0.49 0.05122 -1.47 0.0005 miRanda -0.54 1.0E-5 NA
71 hsa-miR-33a-5p CACNA1C 0.41 0.32143 -1.47 0.0005 MirTarget -0.51 0 NA
72 hsa-miR-33b-5p CACNA1C 0.27 0.61481 -1.47 0.0005 MirTarget -0.38 0 NA
73 hsa-miR-378a-5p CACNA1C -0.56 0.03446 -1.47 0.0005 MirTarget -0.53 0 NA
74 hsa-miR-3922-3p CACNA1C 1.33 0.00067 -1.47 0.0005 mirMAP; miRNATAP -0.33 0.00023 NA
75 hsa-miR-421 CACNA1C 1.81 0 -1.47 0.0005 MirTarget; PITA; miRanda; miRNATAP -0.32 0.00018 NA
76 hsa-miR-429 CACNA1C 1.4 0.009 -1.47 0.0005 MirTarget; PITA; miRanda; miRNATAP -0.25 1.0E-5 NA
77 hsa-miR-484 CACNA1C 0.71 0.00234 -1.47 0.0005 PITA; miRNATAP -0.74 0 NA
78 hsa-miR-542-3p CACNA1C 0.76 0.00211 -1.47 0.0005 miRanda -0.33 0.00762 NA
79 hsa-miR-577 CACNA1C 0.91 0.22561 -1.47 0.0005 PITA -0.15 0.00039 NA
80 hsa-miR-582-5p CACNA1C -0.45 0.13462 -1.47 0.0005 PITA -0.35 0.00052 NA
81 hsa-miR-589-3p CACNA1C 1.02 0.00578 -1.47 0.0005 MirTarget; mirMAP -0.27 0.00102 NA
82 hsa-miR-671-3p CACNA1C 1.16 0.0004 -1.47 0.0005 miRNATAP -0.52 0 NA
83 hsa-miR-7-1-3p CACNA1C 0.71 0.04123 -1.47 0.0005 MirTarget -0.29 0.00107 NA
84 hsa-miR-877-5p CACNA1C 2.18 0 -1.47 0.0005 MirTarget -0.38 0 NA
85 hsa-miR-93-3p CACNA1C 1.89 0 -1.47 0.0005 mirMAP -0.59 0 NA
86 hsa-miR-944 CACNA1C 3.33 0.01778 -1.47 0.0005 mirMAP -0.11 1.0E-5 NA
87 hsa-miR-96-5p CACNA1C 1.14 0.00943 -1.47 0.0005 MirTarget; TargetScan -0.47 0 NA
88 hsa-let-7a-2-3p CACNA1D 0.2 0.64356 -0.15 0.86217 MirTarget -0.48 0.00099 NA
89 hsa-let-7b-5p CACNA1D 0.06 0.7814 -0.15 0.86217 miRNATAP -1.4 0 NA
90 hsa-miR-134-5p CACNA1D 0.57 0.10962 -0.15 0.86217 MirTarget -0.8 0 NA
91 hsa-miR-203a-3p CACNA1E 1.45 0.03941 -0.45 0.53451 MirTarget -0.23 0.00165 NA
92 hsa-miR-205-5p CACNA1E 3.14 0.02932 -0.45 0.53451 mirMAP -0.11 0.00145 NA
93 hsa-miR-151a-3p CACNA1G 1 1.0E-5 -0.55 0.31183 MirTarget -0.49 0.00446 NA
94 hsa-miR-32-5p CACNA1H 0.42 0.10646 -2.22 1.0E-5 miRNATAP -0.72 0 NA
95 hsa-miR-361-3p CACNA1H -0.13 0.56605 -2.22 1.0E-5 MirTarget; mirMAP -0.44 0.0094 NA
96 hsa-miR-92a-3p CACNA1H 1.22 1.0E-5 -2.22 1.0E-5 miRNATAP -0.98 0 NA
97 hsa-let-7f-1-3p CACNA2D1 1.29 0 -1.61 0.02537 mirMAP -0.72 0.00016 NA
98 hsa-miR-107 CACNA2D1 0.9 5.0E-5 -1.61 0.02537 PITA; miRanda; miRNATAP -1.07 0 NA
99 hsa-miR-141-3p CACNA2D1 1.46 0.00116 -1.61 0.02537 TargetScan -0.33 0.00413 NA
100 hsa-miR-16-2-3p CACNA2D1 1.8 0 -1.61 0.02537 mirMAP -0.49 0.00268 NA
101 hsa-miR-16-5p CACNA2D1 1.01 1.0E-5 -1.61 0.02537 miRNAWalker2 validate -1.06 0 NA
102 hsa-miR-181b-5p CACNA2D1 1.64 0 -1.61 0.02537 mirMAP -0.45 0.00934 NA
103 hsa-miR-200b-3p CACNA2D1 0.97 0.0595 -1.61 0.02537 TargetScan -0.32 0.00136 NA
104 hsa-miR-32-3p CACNA2D1 0.58 0.11837 -1.61 0.02537 mirMAP -0.44 0.00468 NA
105 hsa-miR-330-3p CACNA2D1 0.8 0.00747 -1.61 0.02537 mirMAP -0.7 4.0E-5 NA
106 hsa-miR-335-3p CACNA2D1 2.52 0 -1.61 0.02537 mirMAP -0.43 0.00023 NA
107 hsa-miR-33a-3p CACNA2D1 0.35 0.32171 -1.61 0.02537 mirMAP -0.45 0.00349 NA
108 hsa-miR-96-5p CACNA2D1 1.14 0.00943 -1.61 0.02537 TargetScan; miRNATAP -0.39 0.00147 NA
109 hsa-miR-182-5p CACNA2D2 0.89 0.03106 -3 0 miRNATAP -0.26 0.00833 NA
110 hsa-miR-205-5p CACNA2D2 3.14 0.02932 -3 0 miRNATAP -0.12 2.0E-5 NA
111 hsa-miR-22-5p CACNA2D2 0.8 0.0008 -3 0 mirMAP -0.54 0.00168 NA
112 hsa-miR-3614-5p CACNA2D2 1.1 0.00706 -3 0 mirMAP -0.33 0.00109 NA
113 hsa-miR-455-3p CACNA2D2 2.3 0 -3 0 PITA; miRNATAP -0.48 0 NA
114 hsa-miR-18a-3p CACNA2D3 2.35 0 -2.09 0.00344 miRNAWalker2 validate -0.52 1.0E-5 NA
115 hsa-miR-429 CACNA2D3 1.4 0.009 -2.09 0.00344 miRanda -0.25 0.00817 NA
116 hsa-miR-615-3p CACNA2D3 2.83 3.0E-5 -2.09 0.00344 miRanda -0.36 0.00037 NA
117 hsa-miR-299-5p CACNB1 -0.17 0.63894 0.77 0.00894 miRNATAP -0.16 0.00455 NA
118 hsa-let-7a-3p CACNB2 0.5 0.04111 -2.09 1.0E-5 MirTarget; mirMAP -0.65 0 NA
119 hsa-let-7b-3p CACNB2 0.22 0.29604 -2.09 1.0E-5 MirTarget; mirMAP -0.77 0 NA
120 hsa-let-7f-1-3p CACNB2 1.29 0 -2.09 1.0E-5 MirTarget; mirMAP -0.71 0 NA
121 hsa-miR-103a-2-5p CACNB2 0.81 0.01999 -2.09 1.0E-5 MirTarget -0.32 0.00095 NA
122 hsa-miR-144-5p CACNB2 -0.64 0.17347 -2.09 1.0E-5 mirMAP -0.26 0.00021 NA
123 hsa-miR-16-5p CACNB2 1.01 1.0E-5 -2.09 1.0E-5 miRNAWalker2 validate -0.99 0 NA
124 hsa-miR-181a-5p CACNB2 1.39 0 -2.09 1.0E-5 miRNATAP -0.51 0.00031 NA
125 hsa-miR-181b-5p CACNB2 1.64 0 -2.09 1.0E-5 miRNATAP -0.45 6.0E-5 NA
126 hsa-miR-182-5p CACNB2 0.89 0.03106 -2.09 1.0E-5 miRNATAP -0.48 0 NA
127 hsa-miR-200c-5p CACNB2 0.84 0.05746 -2.09 1.0E-5 MirTarget; miRNATAP -0.24 0.00451 NA
128 hsa-miR-23a-3p CACNB2 1.11 0 -2.09 1.0E-5 mirMAP -0.91 0 NA
129 hsa-miR-27a-3p CACNB2 1.3 0 -2.09 1.0E-5 MirTarget; miRNATAP -0.87 0 NA
130 hsa-miR-29a-5p CACNB2 0.59 0.02301 -2.09 1.0E-5 MirTarget -0.38 0.00392 NA
131 hsa-miR-31-5p CACNB2 0.67 0.3818 -2.09 1.0E-5 MirTarget; miRNATAP -0.24 0 NA
132 hsa-miR-32-3p CACNB2 0.58 0.11837 -2.09 1.0E-5 mirMAP; miRNATAP -0.37 0.00029 NA
133 hsa-miR-339-5p CACNB2 0.77 0.00817 -2.09 1.0E-5 miRNATAP -0.51 1.0E-5 NA
134 hsa-miR-3653-3p CACNB2 0.6 0.09439 -2.09 1.0E-5 MirTarget -0.26 0.00537 NA
135 hsa-miR-369-3p CACNB2 0.32 0.35899 -2.09 1.0E-5 PITA -0.26 0.00792 NA
136 hsa-miR-370-3p CACNB2 1.03 0.00666 -2.09 1.0E-5 MirTarget -0.27 0.00202 NA
137 hsa-miR-429 CACNB2 1.4 0.009 -2.09 1.0E-5 PITA; miRanda; miRNATAP -0.28 0 NA
138 hsa-miR-550a-3p CACNB2 2.06 0 -2.09 1.0E-5 MirTarget; miRNATAP -0.45 0 NA
139 hsa-miR-590-3p CACNB2 1.12 0.00016 -2.09 1.0E-5 mirMAP -0.61 0 NA
140 hsa-miR-615-3p CACNB2 2.83 3.0E-5 -2.09 1.0E-5 miRanda -0.31 0 NA
141 hsa-miR-654-5p CACNB2 0.97 0.00586 -2.09 1.0E-5 MirTarget -0.27 0.00721 NA
142 hsa-miR-7-1-3p CACNB2 0.71 0.04123 -2.09 1.0E-5 mirMAP -0.27 0.00506 NA
143 hsa-miR-93-3p CACNB2 1.89 0 -2.09 1.0E-5 MirTarget; miRNATAP -0.51 0 NA
144 hsa-miR-96-5p CACNB2 1.14 0.00943 -2.09 1.0E-5 miRNATAP -0.5 0 NA
145 hsa-miR-140-3p CACNB3 -0.3 0.12754 0.57 0.0123 PITA; miRNATAP -0.25 0.00312 NA
146 hsa-miR-186-5p CACNB3 0.15 0.43471 0.57 0.0123 miRNATAP -0.41 0 NA
147 hsa-miR-339-5p CACNB3 0.77 0.00817 0.57 0.0123 miRanda -0.15 0.00771 NA
148 hsa-miR-361-3p CACNB3 -0.13 0.56605 0.57 0.0123 mirMAP -0.4 0 NA
149 hsa-let-7d-5p CACNB4 0.98 0 -2.12 0.00021 miRNATAP -0.61 0.00337 NA
150 hsa-miR-107 CACNB4 0.9 5.0E-5 -2.12 0.00021 miRanda -0.52 0.00544 NA
NumGOOverlapSizeP ValueAdj. P Value
1 INTRACELLULAR SIGNAL TRANSDUCTION 111 1572 1.403e-82 6.528e-79
2 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 74 404 9.736e-82 2.265e-78
3 PROTEIN PHOSPHORYLATION 93 944 1.839e-79 2.852e-76
4 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 110 1977 2.142e-70 2.491e-67
5 REGULATION OF MAPK CASCADE 77 660 1.467e-69 1.365e-66
6 PHOSPHORYLATION 93 1228 8.052e-69 6.245e-66
7 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 101 1656 7.833e-67 5.207e-64
8 POSITIVE REGULATION OF RESPONSE TO STIMULUS 103 1929 9.221e-63 5.363e-60
9 REGULATION OF PROTEIN MODIFICATION PROCESS 98 1710 9.29e-62 4.803e-59
10 POSITIVE REGULATION OF MOLECULAR FUNCTION 99 1791 4.637e-61 2.158e-58
11 POSITIVE REGULATION OF MAPK CASCADE 63 470 1.208e-59 5.111e-57
12 REGULATION OF PHOSPHORUS METABOLIC PROCESS 94 1618 3.814e-59 1.479e-56
13 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 76 876 1.081e-58 3.869e-56
14 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 80 1036 3.084e-58 9.567e-56
15 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 80 1036 3.084e-58 9.567e-56
16 REGULATION OF MAP KINASE ACTIVITY 55 319 6.908e-58 2.009e-55
17 POSITIVE REGULATION OF KINASE ACTIVITY 62 482 1.763e-57 4.826e-55
18 REGULATION OF KINASE ACTIVITY 72 776 2.653e-57 6.857e-55
19 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 60 470 2.751e-55 6.738e-53
20 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 79 1135 6.455e-54 1.502e-51
21 POSITIVE REGULATION OF CELL COMMUNICATION 86 1532 8.055e-52 1.785e-49
22 REGULATION OF TRANSFERASE ACTIVITY 72 946 3.436e-51 7.267e-49
23 POSITIVE REGULATION OF CATALYTIC ACTIVITY 85 1518 5.246e-51 1.061e-48
24 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 62 616 8.893e-51 1.724e-48
25 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 84 1492 1.78e-50 3.314e-48
26 ACTIVATION OF PROTEIN KINASE ACTIVITY 46 279 4.152e-47 7.431e-45
27 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 40 289 1.158e-37 1.995e-35
28 REGULATION OF CELL DEATH 68 1472 4.321e-34 7.18e-32
29 POSITIVE REGULATION OF MAP KINASE ACTIVITY 32 207 1.093e-31 1.753e-29
30 RESPONSE TO GROWTH FACTOR 41 475 3.327e-30 5.16e-28
31 STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 25 103 4.052e-30 6.082e-28
32 REGULATION OF RESPONSE TO STRESS 61 1468 1.147e-27 1.667e-25
33 ACTIVATION OF MAPKK ACTIVITY 19 52 5.388e-27 7.597e-25
34 JNK CASCADE 21 82 5.663e-26 7.75e-24
35 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 43 689 6.162e-26 8.192e-24
36 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 27 197 2.407e-25 3.111e-23
37 CELL DEATH 49 1001 6.035e-25 7.589e-23
38 IMMUNE RESPONSE REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 31 323 3.2e-24 3.919e-22
39 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 63 1848 5.994e-24 7.151e-22
40 ACTIVATION OF MAPK ACTIVITY 23 137 8.483e-24 9.868e-22
41 REGULATION OF IMMUNE SYSTEM PROCESS 55 1403 1.746e-23 1.982e-21
42 FC EPSILON RECEPTOR SIGNALING PATHWAY 23 142 2.011e-23 2.228e-21
43 REGULATION OF IMMUNE RESPONSE 44 858 4.176e-23 4.519e-21
44 POSITIVE REGULATION OF CELL DEATH 38 605 5.668e-23 5.994e-21
45 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 31 365 1.279e-22 1.323e-20
46 NEGATIVE REGULATION OF CELL DEATH 43 872 6.603e-22 6.679e-20
47 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 34 498 1.04e-21 1.03e-19
48 PEPTIDYL AMINO ACID MODIFICATION 42 841 1.358e-21 1.316e-19
49 REGULATION OF CELL DIFFERENTIATION 54 1492 2.084e-21 1.979e-19
50 REGULATION OF TRANSPORT 59 1804 2.313e-21 2.153e-19
51 REGULATION OF JNK CASCADE 22 159 6.91e-21 6.304e-19
52 NEGATIVE REGULATION OF CELL COMMUNICATION 48 1192 8.323e-21 7.448e-19
53 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 47 1142 9.668e-21 8.487e-19
54 CELL DEVELOPMENT 52 1426 1.052e-20 9.062e-19
55 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 56 1672 1.16e-20 9.811e-19
56 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 58 1805 1.365e-20 1.134e-18
57 CELL CELL SIGNALING 39 767 2.639e-20 2.154e-18
58 PEPTIDYL SERINE MODIFICATION 21 148 3.248e-20 2.606e-18
59 POSITIVE REGULATION OF GENE EXPRESSION 56 1733 6.245e-20 4.925e-18
60 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 20 135 1.103e-19 8.416e-18
61 CELLULAR RESPONSE TO STRESS 53 1565 1.1e-19 8.416e-18
62 FC RECEPTOR SIGNALING PATHWAY 23 206 1.239e-19 9.297e-18
63 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 43 1021 2.685e-19 1.983e-17
64 RESPONSE TO ABIOTIC STIMULUS 43 1024 2.998e-19 2.179e-17
65 REGULATION OF NEURON DEATH 24 252 8.145e-19 5.831e-17
66 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 48 1360 1.885e-18 1.329e-16
67 REGULATION OF CELL PROLIFERATION 49 1496 1.598e-17 1.11e-15
68 RESPONSE TO EXTERNAL STIMULUS 54 1821 1.669e-17 1.142e-15
69 REGULATION OF HYDROLASE ACTIVITY 46 1327 2.373e-17 1.6e-15
70 RESPONSE TO ENDOGENOUS STIMULUS 48 1450 2.476e-17 1.646e-15
71 REGULATION OF CELLULAR RESPONSE TO STRESS 34 691 2.796e-17 1.832e-15
72 POSITIVE REGULATION OF CELL PROLIFERATION 36 814 8.26e-17 5.338e-15
73 REGULATION OF CELLULAR COMPONENT MOVEMENT 35 771 1.071e-16 6.829e-15
74 RESPONSE TO OXYGEN CONTAINING COMPOUND 46 1381 1.096e-16 6.889e-15
75 POSITIVE REGULATION OF CELL DIFFERENTIATION 36 823 1.167e-16 7.242e-15
76 PROTEIN AUTOPHOSPHORYLATION 20 192 1.341e-16 8.211e-15
77 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 46 1395 1.609e-16 9.723e-15
78 VASCULATURE DEVELOPMENT 28 469 1.911e-16 1.14e-14
79 CARDIOVASCULAR SYSTEM DEVELOPMENT 35 788 2.091e-16 1.216e-14
80 CIRCULATORY SYSTEM DEVELOPMENT 35 788 2.091e-16 1.216e-14
81 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 39 1008 3.029e-16 1.74e-14
82 POSITIVE REGULATION OF HYDROLASE ACTIVITY 37 905 3.554e-16 2.017e-14
83 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 36 867 5.942e-16 3.331e-14
84 REGULATION OF ERK1 AND ERK2 CASCADE 21 238 6.684e-16 3.703e-14
85 PEPTIDYL TYROSINE MODIFICATION 19 186 1.16e-15 6.349e-14
86 WOUND HEALING 27 470 1.802e-15 9.751e-14
87 REGULATION OF NEURON APOPTOTIC PROCESS 19 192 2.097e-15 1.121e-13
88 MEMBRANE DEPOLARIZATION 13 61 2.368e-15 1.252e-13
89 RESPONSE TO WOUNDING 29 563 2.518e-15 1.316e-13
90 RAS PROTEIN SIGNAL TRANSDUCTION 17 143 3.07e-15 1.587e-13
91 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 30 616 3.502e-15 1.791e-13
92 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 39 1087 3.643e-15 1.842e-13
93 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 20 228 3.832e-15 1.917e-13
94 NEGATIVE REGULATION OF MAPK CASCADE 17 145 3.888e-15 1.925e-13
95 ORGAN MORPHOGENESIS 34 841 9.598e-15 4.701e-13
96 IMMUNE SYSTEM PROCESS 52 1984 1.356e-14 6.571e-13
97 POSITIVE REGULATION OF NF KAPPAB TRANSCRIPTION FACTOR ACTIVITY 16 132 1.52e-14 7.29e-13
98 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 23 352 1.746e-14 8.291e-13
99 TISSUE DEVELOPMENT 45 1518 1.861e-14 8.747e-13
100 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 39 1152 2.395e-14 1.114e-12
101 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 25 437 2.422e-14 1.116e-12
102 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 27 541 5.491e-14 2.48e-12
103 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 27 541 5.491e-14 2.48e-12
104 REGULATION OF ION TRANSPORT 28 592 6.708e-14 3.001e-12
105 TUBE DEVELOPMENT 27 552 8.89e-14 3.939e-12
106 NEGATIVE REGULATION OF PHOSPHORYLATION 24 422 9.523e-14 4.18e-12
107 REGULATION OF TRANSMEMBRANE TRANSPORT 24 426 1.169e-13 5.085e-12
108 NEUROGENESIS 42 1402 1.234e-13 5.317e-12
109 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 16 153 1.591e-13 6.792e-12
110 POSITIVE REGULATION OF TRANSPORT 34 936 2.084e-13 8.816e-12
111 CALCIUM ION TRANSMEMBRANE TRANSPORT 16 159 2.913e-13 1.221e-11
112 REGULATION OF APOPTOTIC SIGNALING PATHWAY 22 363 3.108e-13 1.291e-11
113 PROTEIN DEPHOSPHORYLATION 17 190 3.557e-13 1.465e-11
114 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 34 957 3.906e-13 1.593e-11
115 INACTIVATION OF MAPK ACTIVITY 9 26 3.937e-13 1.593e-11
116 CALCIUM ION TRANSPORT 18 223 4.115e-13 1.651e-11
117 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 15 138 5.317e-13 2.114e-11
118 REGULATION OF CELLULAR LOCALIZATION 39 1277 6.289e-13 2.48e-11
119 POSITIVE REGULATION OF LOCOMOTION 23 420 7.154e-13 2.797e-11
120 MODULATION OF SYNAPTIC TRANSMISSION 20 301 7.362e-13 2.855e-11
121 NEGATIVE REGULATION OF MAP KINASE ACTIVITY 12 73 7.899e-13 3.038e-11
122 HEART DEVELOPMENT 24 466 8.099e-13 3.089e-11
123 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 34 983 8.304e-13 3.141e-11
124 CELLULAR RESPONSE TO CARBOHYDRATE STIMULUS 12 74 9.362e-13 3.513e-11
125 ACTIVATION OF IMMUNE RESPONSE 23 427 1.007e-12 3.689e-11
126 POSITIVE REGULATION OF ERK1 AND ERK2 CASCADE 16 172 9.932e-13 3.689e-11
127 POSITIVE REGULATION OF IMMUNE RESPONSE 26 563 1.001e-12 3.689e-11
128 REGULATION OF GTPASE ACTIVITY 28 673 1.517e-12 5.515e-11
129 GLAND DEVELOPMENT 22 395 1.684e-12 6.075e-11
130 INOSITOL LIPID MEDIATED SIGNALING 14 124 1.924e-12 6.887e-11
131 MORPHOGENESIS OF AN EPITHELIUM 22 400 2.161e-12 7.677e-11
132 BLOOD VESSEL MORPHOGENESIS 21 364 2.872e-12 1.012e-10
133 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 30 799 2.946e-12 1.031e-10
134 NEURON PROJECTION DEVELOPMENT 25 545 3.315e-12 1.151e-10
135 CARDIAC CONDUCTION 12 82 3.339e-12 1.151e-10
136 RESPONSE TO RADIATION 22 413 4.067e-12 1.391e-10
137 INNATE IMMUNE RESPONSE ACTIVATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 13 106 4.172e-12 1.417e-10
138 FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 12 84 4.49e-12 1.514e-10
139 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 20 337 5.88e-12 1.968e-10
140 REGULATION OF CYTOKINE PRODUCTION 25 563 6.719e-12 2.233e-10
141 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 33 1004 7.572e-12 2.499e-10
142 EPITHELIUM DEVELOPMENT 32 945 7.645e-12 2.505e-10
143 POSITIVE REGULATION OF CELL DEVELOPMENT 23 472 7.828e-12 2.547e-10
144 CELL ACTIVATION 25 568 8.136e-12 2.629e-10
145 REGULATION OF CELL DEVELOPMENT 30 836 9.138e-12 2.932e-10
146 DIVALENT INORGANIC CATION TRANSPORT 18 268 9.256e-12 2.95e-10
147 NEGATIVE REGULATION OF MOLECULAR FUNCTION 34 1079 1.095e-11 3.467e-10
148 PLATELET ACTIVATION 14 142 1.248e-11 3.925e-10
149 ACTIVATION OF INNATE IMMUNE RESPONSE 16 204 1.364e-11 4.259e-10
150 NEURON DEVELOPMENT 27 687 1.476e-11 4.58e-10
151 REGULATION OF INNATE IMMUNE RESPONSE 20 357 1.673e-11 5.156e-10
152 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 19 321 2.155e-11 6.596e-10
153 MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL 9 39 2.437e-11 7.411e-10
154 REGULATION OF DEFENSE RESPONSE 28 759 2.61e-11 7.836e-10
155 LOCOMOTION 34 1114 2.608e-11 7.836e-10
156 NEURON DIFFERENTIATION 30 874 2.742e-11 8.178e-10
157 MULTICELLULAR ORGANISMAL SIGNALING 13 123 2.854e-11 8.458e-10
158 NEGATIVE REGULATION OF KINASE ACTIVITY 17 250 2.966e-11 8.734e-10
159 HEAD DEVELOPMENT 27 709 3.022e-11 8.845e-10
160 APOPTOTIC SIGNALING PATHWAY 18 289 3.241e-11 9.427e-10
161 LIPID PHOSPHORYLATION 12 99 3.303e-11 9.545e-10
162 PEPTIDYL TYROSINE DEPHOSPHORYLATION 12 100 3.727e-11 1.07e-09
163 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 13 126 3.884e-11 1.109e-09
164 REGULATION OF PROTEIN LOCALIZATION 31 950 4.355e-11 1.236e-09
165 EMBRYO DEVELOPMENT 30 894 4.773e-11 1.346e-09
166 CELL PROJECTION ORGANIZATION 30 902 5.931e-11 1.662e-09
167 REGULATION OF JUN KINASE ACTIVITY 11 81 6.346e-11 1.768e-09
168 RESPONSE TO DRUG 21 431 6.857e-11 1.899e-09
169 POSITIVE REGULATION OF CELL DIVISION 13 132 7.023e-11 1.934e-09
170 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 14 162 7.455e-11 2.041e-09
171 REGULATION OF GROWTH 25 633 8.242e-11 2.243e-09
172 IMMUNE SYSTEM DEVELOPMENT 24 582 8.502e-11 2.3e-09
173 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 13 135 9.337e-11 2.511e-09
174 POSITIVE REGULATION OF JUN KINASE ACTIVITY 10 63 9.739e-11 2.604e-09
175 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 16 233 1.006e-10 2.676e-09
176 REGULATION OF EPITHELIAL CELL MIGRATION 14 166 1.034e-10 2.735e-09
177 EMBRYONIC MORPHOGENESIS 23 539 1.115e-10 2.93e-09
178 PEPTIDYL THREONINE MODIFICATION 9 46 1.206e-10 3.135e-09
179 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 9 46 1.206e-10 3.135e-09
180 RESPONSE TO CARBOHYDRATE 14 168 1.214e-10 3.139e-09
181 REGULATION OF SECRETION 26 699 1.223e-10 3.143e-09
182 CENTRAL NERVOUS SYSTEM DEVELOPMENT 29 872 1.301e-10 3.326e-09
183 POSITIVE REGULATION OF GROWTH 16 238 1.38e-10 3.508e-09
184 NEGATIVE REGULATION OF NEURON DEATH 14 171 1.538e-10 3.89e-09
185 RESPONSE TO LIGHT STIMULUS 17 280 1.751e-10 4.404e-09
186 REGULATION OF CELL MORPHOGENESIS 23 552 1.782e-10 4.457e-09
187 POSITIVE REGULATION OF NEURON DEATH 10 67 1.837e-10 4.571e-09
188 POSITIVE REGULATION OF DEFENSE RESPONSE 19 364 1.853e-10 4.585e-09
189 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 28 829 1.995e-10 4.902e-09
190 TUBE MORPHOGENESIS 18 323 2.001e-10 4.902e-09
191 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 13 144 2.107e-10 5.132e-09
192 REGULATION OF CALCIUM ION TRANSPORT 15 209 2.141e-10 5.188e-09
193 RESPONSE TO FIBROBLAST GROWTH FACTOR 12 116 2.178e-10 5.252e-09
194 PHOSPHATIDYLINOSITOL 3 PHOSPHATE BIOSYNTHETIC PROCESS 9 49 2.202e-10 5.281e-09
195 POSITIVE REGULATION OF INNATE IMMUNE RESPONSE 16 246 2.251e-10 5.372e-09
196 RESPONSE TO MECHANICAL STIMULUS 15 210 2.289e-10 5.434e-09
197 REGULATION OF EPITHELIAL CELL PROLIFERATION 17 285 2.304e-10 5.441e-09
198 DEPHOSPHORYLATION 17 286 2.432e-10 5.716e-09
199 POSITIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 14 179 2.827e-10 6.61e-09
200 REGULATION OF INTRACELLULAR TRANSPORT 24 621 3.172e-10 7.379e-09
201 ACTION POTENTIAL 11 94 3.296e-10 7.629e-09
202 ANGIOGENESIS 17 293 3.533e-10 8.139e-09
203 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 12 121 3.578e-10 8.2e-09
204 REGULATION OF PROTEIN IMPORT 14 183 3.788e-10 8.641e-09
205 REGULATION OF ORGAN GROWTH 10 73 4.412e-10 1.001e-08
206 SINGLE ORGANISM BEHAVIOR 19 384 4.561e-10 1.03e-08
207 POSITIVE REGULATION OF PHOSPHOLIPASE ACTIVITY 9 53 4.617e-10 1.038e-08
208 REGULATION OF HEART CONTRACTION 15 221 4.675e-10 1.046e-08
209 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 13 154 4.875e-10 1.085e-08
210 REGULATION OF ORGANELLE ORGANIZATION 33 1178 4.96e-10 1.099e-08
211 REGULATION OF MEMBRANE POTENTIAL 18 343 5.275e-10 1.163e-08
212 TISSUE MORPHOGENESIS 22 533 5.487e-10 1.204e-08
213 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 26 750 5.543e-10 1.211e-08
214 EXTRINSIC APOPTOTIC SIGNALING PATHWAY 11 99 5.808e-10 1.263e-08
215 PHOSPHATIDYLINOSITOL METABOLIC PROCESS 14 193 7.636e-10 1.653e-08
216 REGULATION OF CELLULAR COMPONENT BIOGENESIS 26 767 8.913e-10 1.92e-08
217 REGULATION OF CELL CYCLE 29 949 9.289e-10 1.983e-08
218 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 34 1275 9.287e-10 1.983e-08
219 REGULATION OF VASCULATURE DEVELOPMENT 15 233 9.736e-10 2.069e-08
220 REGULATION OF CELL DIVISION 16 272 9.812e-10 2.075e-08
221 RESPONSE TO CYTOKINE 25 714 1.009e-09 2.124e-08
222 NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR SIGNALING PATHWAY 7 28 2.343e-09 4.91e-08
223 SYNAPTIC SIGNALING 19 424 2.362e-09 4.928e-08
224 REGULATION OF PHOSPHOLIPASE ACTIVITY 9 64 2.656e-09 5.517e-08
225 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 14 213 2.76e-09 5.708e-08
226 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 7 29 3.067e-09 6.314e-08
227 REGULATION OF CYTOPLASMIC TRANSPORT 20 481 3.138e-09 6.433e-08
228 RESPONSE TO HEAT 10 89 3.225e-09 6.581e-08
229 REGULATION OF CHEMOTAXIS 13 180 3.328e-09 6.761e-08
230 POSITIVE REGULATION OF LIPASE ACTIVITY 9 66 3.519e-09 7.12e-08
231 RESPONSE TO TEMPERATURE STIMULUS 12 148 3.681e-09 7.416e-08
232 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 14 218 3.724e-09 7.469e-08
233 REGULATION OF PROTEIN SECRETION 18 389 3.879e-09 7.746e-08
234 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 14 220 4.189e-09 8.33e-08
235 RESPONSE TO LIPID 27 888 4.258e-09 8.43e-08
236 POSITIVE REGULATION OF CHEMOTAXIS 11 120 4.609e-09 9.086e-08
237 POSITIVE REGULATION OF DNA METABOLIC PROCESS 13 185 4.642e-09 9.114e-08
238 SENSORY ORGAN DEVELOPMENT 20 493 4.769e-09 9.323e-08
239 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 8 48 5.159e-09 1.004e-07
240 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 22 602 5.188e-09 1.006e-07
241 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 17 351 5.471e-09 1.056e-07
242 CELLULAR COMPONENT MORPHOGENESIS 27 900 5.661e-09 1.088e-07
243 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 10 95 6.142e-09 1.176e-07
244 ACTIN FILAMENT BASED PROCESS 19 450 6.24e-09 1.19e-07
245 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 21 554 6.308e-09 1.198e-07
246 SALIVARY GLAND DEVELOPMENT 7 32 6.478e-09 1.225e-07
247 HEMOSTASIS 16 311 6.727e-09 1.267e-07
248 FACE DEVELOPMENT 8 50 7.238e-09 1.358e-07
249 REGULATION OF SYSTEM PROCESS 20 507 7.649e-09 1.429e-07
250 CYTOPLASMIC PATTERN RECOGNITION RECEPTOR SIGNALING PATHWAY 7 33 8.165e-09 1.52e-07
251 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 10 98 8.334e-09 1.545e-07
252 ANTIGEN RECEPTOR MEDIATED SIGNALING PATHWAY 13 195 8.769e-09 1.619e-07
253 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 20 514 9.629e-09 1.771e-07
254 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 11 129 9.911e-09 1.816e-07
255 BEHAVIOR 20 516 1.028e-08 1.875e-07
256 REGULATION OF TRANSPORTER ACTIVITY 13 198 1.054e-08 1.915e-07
257 REGULATION OF CELL ADHESION 22 629 1.147e-08 2.076e-07
258 REGULATION OF METAL ION TRANSPORT 16 325 1.254e-08 2.261e-07
259 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 10 103 1.355e-08 2.434e-07
260 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 11 133 1.366e-08 2.443e-07
261 REGULATION OF BINDING 15 283 1.37e-08 2.443e-07
262 MORPHOGENESIS OF A BRANCHING STRUCTURE 12 167 1.446e-08 2.568e-07
263 POSITIVE REGULATION OF PROTEIN IMPORT 10 104 1.489e-08 2.634e-07
264 RESPONSE TO INORGANIC SUBSTANCE 19 479 1.706e-08 3.007e-07
265 REGULATION OF DEVELOPMENTAL GROWTH 15 289 1.813e-08 3.184e-07
266 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 12 171 1.885e-08 3.298e-07
267 MUSCLE STRUCTURE DEVELOPMENT 18 432 1.968e-08 3.429e-07
268 STRIATED MUSCLE CELL DIFFERENTIATION 12 173 2.147e-08 3.728e-07
269 CELL MOTILITY 25 835 2.32e-08 3.998e-07
270 LOCALIZATION OF CELL 25 835 2.32e-08 3.998e-07
271 REGULATION OF SYNAPTIC PLASTICITY 11 140 2.336e-08 4.012e-07
272 REGULATION OF BLOOD CIRCULATION 15 295 2.383e-08 4.077e-07
273 NEUROTROPHIN SIGNALING PATHWAY 6 23 2.587e-08 4.409e-07
274 GLYCEROPHOSPHOLIPID METABOLIC PROCESS 15 297 2.607e-08 4.427e-07
275 RHYTHMIC PROCESS 15 298 2.726e-08 4.612e-07
276 REGULATION OF LIPASE ACTIVITY 9 83 2.773e-08 4.675e-07
277 POSITIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 14 258 3.172e-08 5.328e-07
278 REGULATION OF NEURON DIFFERENTIATION 20 554 3.343e-08 5.595e-07
279 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 15 303 3.397e-08 5.665e-07
280 CELL PROLIFERATION 22 672 3.722e-08 6.185e-07
281 REGULATION OF CELL PROJECTION ORGANIZATION 20 558 3.762e-08 6.23e-07
282 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 38 1784 3.886e-08 6.412e-07
283 RESPONSE TO NITROGEN COMPOUND 25 859 4.027e-08 6.617e-07
284 REGULATION OF PROTEIN TARGETING 15 307 4.038e-08 6.617e-07
285 HOMEOSTATIC PROCESS 32 1337 4.155e-08 6.784e-07
286 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 26 926 4.275e-08 6.93e-07
287 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 10 116 4.275e-08 6.93e-07
288 INTERLEUKIN 1 MEDIATED SIGNALING PATHWAY 5 13 4.388e-08 7.089e-07
289 REGULATION OF VOLTAGE GATED CALCIUM CHANNEL ACTIVITY 6 25 4.477e-08 7.208e-07
290 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 24 801 4.51e-08 7.237e-07
291 NEGATIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 9 88 4.654e-08 7.441e-07
292 REGULATION OF HEART GROWTH 7 42 4.845e-08 7.72e-07
293 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 19 513 5.061e-08 8.037e-07
294 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 16 360 5.215e-08 8.253e-07
295 REGULATION OF VESICLE MEDIATED TRANSPORT 18 462 5.457e-08 8.607e-07
296 CALCIUM MEDIATED SIGNALING 9 90 5.672e-08 8.917e-07
297 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 13 229 5.922e-08 9.278e-07
298 MEMBRANE DEPOLARIZATION DURING CARDIAC MUSCLE CELL ACTION POTENTIAL 5 14 6.78e-08 1.055e-06
299 POSITIVE REGULATION OF P38MAPK CASCADE 5 14 6.78e-08 1.055e-06
300 REPRODUCTION 31 1297 7.258e-08 1.126e-06
301 RESPONSE TO BIOTIC STIMULUS 25 886 7.311e-08 1.13e-06
302 CONNECTIVE TISSUE DEVELOPMENT 12 194 7.638e-08 1.177e-06
303 RESPONSE TO BACTERIUM 19 528 7.948e-08 1.22e-06
304 EXOCRINE SYSTEM DEVELOPMENT 7 45 7.982e-08 1.222e-06
305 NEGATIVE REGULATION OF CELL PROLIFERATION 21 643 8.135e-08 1.241e-06
306 EYE DEVELOPMENT 15 326 8.867e-08 1.344e-06
307 MUSCLE CELL DIFFERENTIATION 13 237 8.848e-08 1.344e-06
308 RESPIRATORY SYSTEM DEVELOPMENT 12 197 9.037e-08 1.365e-06
309 NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 12 200 1.066e-07 1.606e-06
310 REGULATION OF CELL ACTIVATION 18 484 1.096e-07 1.624e-06
311 GLAND MORPHOGENESIS 9 97 1.093e-07 1.624e-06
312 THYMUS DEVELOPMENT 7 47 1.091e-07 1.624e-06
313 POSITIVE REGULATION OF LIPID METABOLIC PROCESS 10 128 1.092e-07 1.624e-06
314 POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS 7 47 1.091e-07 1.624e-06
315 I KAPPAB KINASE NF KAPPAB SIGNALING 8 70 1.107e-07 1.63e-06
316 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 8 70 1.107e-07 1.63e-06
317 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 16 381 1.134e-07 1.665e-06
318 POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 6 29 1.168e-07 1.71e-06
319 SYSTEM PROCESS 37 1785 1.23e-07 1.795e-06
320 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 10 131 1.36e-07 1.977e-06
321 RESPONSE TO ORGANIC CYCLIC COMPOUND 25 917 1.408e-07 2.041e-06
322 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 12 208 1.634e-07 2.362e-06
323 COGNITION 13 251 1.722e-07 2.48e-06
324 LIPID MODIFICATION 12 210 1.813e-07 2.604e-06
325 CELLULAR GLUCOSE HOMEOSTASIS 8 75 1.91e-07 2.734e-06
326 REGULATION OF ENDOTHELIAL CELL CHEMOTAXIS 5 17 2.054e-07 2.932e-06
327 REGULATION OF PEPTIDE TRANSPORT 13 256 2.161e-07 3.075e-06
328 POSITIVE REGULATION OF LIPID KINASE ACTIVITY 6 32 2.184e-07 3.098e-06
329 INFLAMMATORY RESPONSE 17 454 2.293e-07 3.243e-06
330 NEURON PROJECTION MORPHOGENESIS 16 402 2.345e-07 3.307e-06
331 CELLULAR CHEMICAL HOMEOSTASIS 19 570 2.592e-07 3.643e-06
332 EMBRYONIC ORGAN DEVELOPMENT 16 406 2.679e-07 3.755e-06
333 GLYCEROLIPID METABOLIC PROCESS 15 356 2.76e-07 3.857e-06
334 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 19 573 2.808e-07 3.912e-06
335 INOSITOL PHOSPHATE MEDIATED SIGNALING 5 18 2.825e-07 3.924e-06
336 REGULATION OF NEURON PROJECTION DEVELOPMENT 16 408 2.862e-07 3.963e-06
337 ERBB SIGNALING PATHWAY 8 79 2.872e-07 3.966e-06
338 CELLULAR MACROMOLECULE LOCALIZATION 29 1234 2.929e-07 4.032e-06
339 PATTERN RECOGNITION RECEPTOR SIGNALING PATHWAY 9 109 2.996e-07 4.112e-06
340 TAXIS 17 464 3.115e-07 4.262e-06
341 CELLULAR RESPONSE TO MECHANICAL STIMULUS 8 80 3.169e-07 4.324e-06
342 CRANIAL SKELETAL SYSTEM DEVELOPMENT 7 55 3.331e-07 4.532e-06
343 PHOSPHOLIPID METABOLIC PROCESS 15 364 3.664e-07 4.971e-06
344 T CELL RECEPTOR SIGNALING PATHWAY 10 146 3.752e-07 5.075e-06
345 POSITIVE REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 5 19 3.809e-07 5.131e-06
346 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 11 184 3.816e-07 5.131e-06
347 CARTILAGE DEVELOPMENT 10 147 3.998e-07 5.361e-06
348 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 15 368 4.21e-07 5.629e-06
349 REGULATION OF PROTEOLYSIS 21 711 4.296e-07 5.728e-06
350 REGULATION OF ENDOTHELIAL CELL MIGRATION 9 114 4.398e-07 5.847e-06
351 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 15 370 4.509e-07 5.96e-06
352 POSITIVE REGULATION OF CYTOKINE PRODUCTION 15 370 4.509e-07 5.96e-06
353 NEUROMUSCULAR JUNCTION DEVELOPMENT 6 36 4.568e-07 6.021e-06
354 RESPONSE TO INTERLEUKIN 1 9 115 4.738e-07 6.227e-06
355 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 12 232 5.288e-07 6.931e-06
356 CARDIAC MUSCLE CELL ACTION POTENTIAL 6 37 5.415e-07 7.077e-06
357 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 10 152 5.449e-07 7.102e-06
358 POSITIVE REGULATION OF DNA REPLICATION 8 86 5.563e-07 7.19e-06
359 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 13 278 5.535e-07 7.19e-06
360 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 8 86 5.563e-07 7.19e-06
361 TISSUE REMODELING 8 87 6.084e-07 7.841e-06
362 CHONDROCYTE DIFFERENTIATION 7 60 6.124e-07 7.871e-06
363 POSITIVE REGULATION OF ORGAN GROWTH 6 38 6.386e-07 8.186e-06
364 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 13 282 6.505e-07 8.315e-06
365 CELLULAR RESPONSE TO INTERLEUKIN 1 8 88 6.645e-07 8.425e-06
366 POSITIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 8 88 6.645e-07 8.425e-06
367 REGULATION OF CATION CHANNEL ACTIVITY 8 88 6.645e-07 8.425e-06
368 PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROCESS 9 120 6.802e-07 8.6e-06
369 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 10 156 6.924e-07 8.73e-06
370 POSITIVE REGULATION OF CELL CYCLE 14 332 6.945e-07 8.734e-06
371 REGULATION OF PHOSPHOLIPASE C ACTIVITY 6 39 7.496e-07 9.37e-06
372 POSITIVE REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 6 39 7.496e-07 9.37e-06
373 REGULATION OF CELLULAR PROTEIN LOCALIZATION 18 552 7.512e-07 9.37e-06
374 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 6 40 8.759e-07 1.087e-05
375 SECOND MESSENGER MEDIATED SIGNALING 10 160 8.736e-07 1.087e-05
376 SKELETAL SYSTEM MORPHOGENESIS 11 201 9.181e-07 1.136e-05
377 REGULATION OF DNA METABOLIC PROCESS 14 340 9.219e-07 1.138e-05
378 REGULATION OF HOMEOSTATIC PROCESS 16 447 9.6e-07 1.182e-05
379 RESPONSE TO UV 9 126 1.027e-06 1.261e-05
380 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 13 296 1.121e-06 1.372e-05
381 MUSCLE CELL DEVELOPMENT 9 128 1.172e-06 1.432e-05
382 POSITIVE REGULATION OF PHOSPHOLIPID METABOLIC PROCESS 6 42 1.181e-06 1.438e-05
383 REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 8 95 1.197e-06 1.454e-05
384 CELLULAR PROCESS INVOLVED IN REPRODUCTION IN MULTICELLULAR ORGANISM 12 252 1.267e-06 1.535e-05
385 REGULATION OF PEPTIDE SECRETION 11 209 1.347e-06 1.628e-05
386 REGULATION OF PROTEIN BINDING 10 168 1.364e-06 1.644e-05
387 RESPONSE TO OXIDATIVE STRESS 14 352 1.389e-06 1.67e-05
388 POSITIVE REGULATION OF ENDOTHELIAL CELL CHEMOTAXIS 4 11 1.409e-06 1.685e-05
389 ACTIVATION OF MAPKKK ACTIVITY 4 11 1.409e-06 1.685e-05
390 LEARNING 9 131 1.423e-06 1.698e-05
391 GLYCEROLIPID BIOSYNTHETIC PROCESS 11 211 1.479e-06 1.76e-05
392 METAL ION TRANSPORT 18 582 1.598e-06 1.896e-05
393 GROWTH 15 410 1.629e-06 1.928e-05
394 STRIATED MUSCLE CONTRACTION 8 99 1.639e-06 1.936e-05
395 HISTONE PHOSPHORYLATION 5 25 1.672e-06 1.97e-05
396 REGULATION OF HOMOTYPIC CELL CELL ADHESION 13 307 1.682e-06 1.976e-05
397 LUNG MORPHOGENESIS 6 45 1.796e-06 2.105e-05
398 CELL GROWTH 9 135 1.83e-06 2.139e-05
399 IN UTERO EMBRYONIC DEVELOPMENT 13 311 1.941e-06 2.263e-05
400 GLIAL CELL DIFFERENTIATION 9 136 1.946e-06 2.263e-05
401 GLIOGENESIS 10 175 1.974e-06 2.291e-05
402 CELLULAR RESPONSE TO EXTERNAL STIMULUS 12 264 2.059e-06 2.366e-05
403 AGING 12 264 2.059e-06 2.366e-05
404 REGULATION OF P38MAPK CASCADE 5 26 2.056e-06 2.366e-05
405 EMBRYONIC CRANIAL SKELETON MORPHOGENESIS 6 46 2.052e-06 2.366e-05
406 REGULATION OF HEMOPOIESIS 13 314 2.158e-06 2.473e-05
407 REGULATION OF MUSCLE TISSUE DEVELOPMENT 8 103 2.214e-06 2.525e-05
408 REGULATION OF MUSCLE ORGAN DEVELOPMENT 8 103 2.214e-06 2.525e-05
409 REGULATION OF IMMUNE EFFECTOR PROCESS 15 424 2.461e-06 2.8e-05
410 POSITIVE REGULATION OF HEART GROWTH 5 27 2.507e-06 2.838e-05
411 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 5 27 2.507e-06 2.838e-05
412 REGULATION OF LIPID KINASE ACTIVITY 6 48 2.652e-06 2.995e-05
413 MULTICELLULAR ORGANISMAL HOMEOSTASIS 12 272 2.805e-06 3.16e-05
414 PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 4 13 3.014e-06 3.379e-05
415 EYELID DEVELOPMENT IN CAMERA TYPE EYE 4 13 3.014e-06 3.379e-05
416 CELLULAR HOMEOSTASIS 19 676 3.282e-06 3.671e-05
417 REGULATION OF CELL CELL ADHESION 14 380 3.39e-06 3.782e-05
418 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 15 437 3.557e-06 3.959e-05
419 REGULATION OF LEUKOCYTE DIFFERENTIATION 11 232 3.709e-06 4.109e-05
420 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 11 232 3.709e-06 4.109e-05
421 REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 6 51 3.813e-06 4.214e-05
422 PROTEIN LOCALIZATION 34 1805 3.882e-06 4.28e-05
423 POSITIVE REGULATION OF CELL GROWTH 9 148 3.915e-06 4.307e-05
424 BONE MORPHOGENESIS 7 79 4.031e-06 4.423e-05
425 MUSCLE SYSTEM PROCESS 12 282 4.066e-06 4.451e-05
426 RESPONSE TO METAL ION 13 333 4.107e-06 4.486e-05
427 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 10 190 4.128e-06 4.499e-05
428 PHOSPHOLIPID BIOSYNTHETIC PROCESS 11 235 4.196e-06 4.561e-05
429 REGULATION OF HEART RATE BY CARDIAC CONDUCTION 5 30 4.338e-06 4.683e-05
430 MYD88 INDEPENDENT TOLL LIKE RECEPTOR SIGNALING PATHWAY 5 30 4.338e-06 4.683e-05
431 RESPONSE TO REACTIVE OXYGEN SPECIES 10 191 4.326e-06 4.683e-05
432 POSITIVE REGULATION OF ION TRANSPORT 11 236 4.37e-06 4.707e-05
433 OVULATION CYCLE 8 113 4.444e-06 4.776e-05
434 RESPONSE TO HORMONE 22 893 4.464e-06 4.786e-05
435 REGULATION OF BODY FLUID LEVELS 16 506 4.74e-06 5.07e-05
436 POSITIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 6 53 4.795e-06 5.117e-05
437 REGULATION OF PEPTIDASE ACTIVITY 14 392 4.847e-06 5.161e-05
438 SINGLE ORGANISM CELLULAR LOCALIZATION 22 898 4.88e-06 5.184e-05
439 CELL PART MORPHOGENESIS 18 633 5.158e-06 5.467e-05
440 CELL CYCLE ARREST 9 154 5.421e-06 5.733e-05
441 MULTICELLULAR ORGANISM REPRODUCTION 20 768 5.589e-06 5.896e-05
442 CYTOSKELETON ORGANIZATION 21 838 5.787e-06 6.082e-05
443 SKELETAL SYSTEM DEVELOPMENT 15 455 5.79e-06 6.082e-05
444 EPIDERMAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 6 55 5.973e-06 6.245e-05
445 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 6 55 5.973e-06 6.245e-05
446 ESTABLISHMENT OF LOCALIZATION IN CELL 32 1676 6.009e-06 6.269e-05
447 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 5 32 6.048e-06 6.282e-05
448 NEGATIVE REGULATION OF SIGNAL TRANSDUCTION IN ABSENCE OF LIGAND 5 32 6.048e-06 6.282e-05
449 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 8 118 6.135e-06 6.358e-05
450 REGULATION OF ENDOCYTOSIS 10 199 6.223e-06 6.435e-05
451 TOLL LIKE RECEPTOR SIGNALING PATHWAY 7 85 6.585e-06 6.779e-05
452 HEART PROCESS 7 85 6.585e-06 6.779e-05
453 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 6 56 6.644e-06 6.825e-05
454 UROGENITAL SYSTEM DEVELOPMENT 12 299 7.376e-06 7.56e-05
455 POSITIVE REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 4 16 7.524e-06 7.695e-05
456 REPRODUCTIVE SYSTEM DEVELOPMENT 14 408 7.645e-06 7.801e-05
457 REGULATION OF DNA REPLICATION 9 161 7.782e-06 7.923e-05
458 OSSIFICATION 11 251 7.853e-06 7.978e-05
459 FOREBRAIN NEURON DEVELOPMENT 5 34 8.247e-06 8.288e-05
460 RESPONSE TO FLUID SHEAR STRESS 5 34 8.247e-06 8.288e-05
461 NUCLEAR TRANSPORT 13 355 8.192e-06 8.288e-05
462 ORGAN FORMATION 5 34 8.247e-06 8.288e-05
463 REGULATION OF MESENCHYMAL CELL PROLIFERATION 5 34 8.247e-06 8.288e-05
464 OVULATION CYCLE PROCESS 7 88 8.296e-06 8.301e-05
465 REGULATION OF STEM CELL PROLIFERATION 7 88 8.296e-06 8.301e-05
466 EPIDERMIS DEVELOPMENT 11 253 8.464e-06 8.451e-05
467 CELLULAR RESPONSE TO BIOTIC STIMULUS 9 163 8.6e-06 8.568e-05
468 FOREBRAIN DEVELOPMENT 13 357 8.7e-06 8.65e-05
469 POSITIVE REGULATION OF DNA BIOSYNTHETIC PROCESS 6 59 9.034e-06 8.963e-05
470 POSITIVE REGULATION OF NEURON DIFFERENTIATION 12 306 9.314e-06 9.221e-05
471 ACTIVATION OF JUN KINASE ACTIVITY 5 35 9.557e-06 9.422e-05
472 BONE REMODELING 5 35 9.557e-06 9.422e-05
473 REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 4 17 9.777e-06 9.617e-05
474 CELL CYCLE 27 1316 1.013e-05 9.941e-05
475 SKIN DEVELOPMENT 10 211 1.041e-05 0.0001017
476 NEGATIVE REGULATION OF CYTOKINE PRODUCTION 10 211 1.041e-05 0.0001017
477 POSITIVE REGULATION OF BINDING 8 127 1.056e-05 0.000103
478 CHEMICAL HOMEOSTASIS 21 874 1.097e-05 0.0001064
479 REGULATION OF PHOSPHOLIPID METABOLIC PROCESS 6 61 1.098e-05 0.0001064
480 POSITIVE REGULATION OF CELL ACTIVATION 12 311 1.096e-05 0.0001064
481 CELLULAR RESPONSE TO HEAT 5 36 1.103e-05 0.0001064
482 POSITIVE REGULATION OF PROTEIN ACETYLATION 5 36 1.103e-05 0.0001064
483 REGULATION OF HORMONE SECRETION 11 262 1.176e-05 0.0001133
484 REGULATION OF REPRODUCTIVE PROCESS 8 129 1.184e-05 0.0001138
485 CELLULAR RESPONSE TO ABIOTIC STIMULUS 11 263 1.218e-05 0.0001169
486 CELL COMMUNICATION INVOLVED IN CARDIAC CONDUCTION 5 37 1.266e-05 0.0001212
487 POSITIVE REGULATION OF SECRETION 13 370 1.273e-05 0.0001216
488 REGULATION OF CYTOKINE BIOSYNTHETIC PROCESS 7 94 1.283e-05 0.0001221
489 REGULATION OF DNA BIOSYNTHETIC PROCESS 7 94 1.283e-05 0.0001221
490 ESTABLISHMENT OF PROTEIN LOCALIZATION 28 1423 1.468e-05 0.0001394
491 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 18 684 1.476e-05 0.0001399
492 NEGATIVE REGULATION OF CELL CYCLE 14 433 1.491e-05 0.0001411
493 POSITIVE REGULATION OF CELL ADHESION 13 376 1.509e-05 0.0001424
494 HOMEOSTASIS OF NUMBER OF CELLS 9 175 1.522e-05 0.0001434
495 RESPONSE TO MUSCLE STRETCH 4 19 1.572e-05 0.0001475
496 NEGATIVE REGULATION OF MEIOTIC CELL CYCLE 4 19 1.572e-05 0.0001475
497 WNT SIGNALING PATHWAY CALCIUM MODULATING PATHWAY 5 39 1.651e-05 0.0001542
498 ERBB2 SIGNALING PATHWAY 5 39 1.651e-05 0.0001542
499 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 6 67 1.895e-05 0.0001763
500 CELLULAR RESPONSE TO DRUG 6 67 1.895e-05 0.0001763
501 TRACHEA DEVELOPMENT 4 20 1.952e-05 0.0001809
502 PROTEIN REFOLDING 4 20 1.952e-05 0.0001809
503 CELLULAR RESPONSE TO NITROGEN COMPOUND 15 505 1.985e-05 0.0001836
504 RESPONSE TO ORGANOPHOSPHORUS 8 139 2.04e-05 0.000188
505 REGULATION OF CHROMOSOME ORGANIZATION 11 278 2.04e-05 0.000188
506 EMBRYONIC ORGAN MORPHOGENESIS 11 279 2.109e-05 0.000194
507 DEVELOPMENTAL GROWTH 12 333 2.16e-05 0.0001983
508 REGULATION OF MYELOID CELL DIFFERENTIATION 9 183 2.172e-05 0.0001989
509 NEGATIVE REGULATION OF IMMUNE EFFECTOR PROCESS 7 102 2.191e-05 0.0002003
510 POSITIVE REGULATION OF AXONOGENESIS 6 69 2.246e-05 0.0002049
511 REGULATION OF CELL GROWTH 13 391 2.274e-05 0.0002071
512 CELL JUNCTION ORGANIZATION 9 185 2.367e-05 0.0002151
513 NEGATIVE REGULATION OF ORGAN GROWTH 4 21 2.396e-05 0.0002173
514 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 6 70 2.439e-05 0.0002208
515 RESPONSE TO TUMOR NECROSIS FACTOR 10 233 2.454e-05 0.0002217
516 RESPONSE TO CAMP 7 104 2.486e-05 0.0002238
517 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 7 104 2.486e-05 0.0002238
518 CEREBRAL CORTEX DEVELOPMENT 7 105 2.645e-05 0.0002373
519 SKIN EPIDERMIS DEVELOPMENT 6 71 2.647e-05 0.0002373
520 INORGANIC ION TRANSMEMBRANE TRANSPORT 16 583 2.732e-05 0.0002444
521 SYNAPSE ORGANIZATION 8 145 2.767e-05 0.0002471
522 POSITIVE REGULATION OF CALCIUM ION TRANSPORT 7 106 2.813e-05 0.0002508
523 CELL CELL SIGNALING INVOLVED IN CARDIAC CONDUCTION 4 22 2.91e-05 0.0002584
524 SOMATIC STEM CELL DIVISION 4 22 2.91e-05 0.0002584
525 MESENCHYME DEVELOPMENT 9 190 2.921e-05 0.0002589
526 DIGESTIVE SYSTEM DEVELOPMENT 8 148 3.206e-05 0.0002836
527 RESPONSE TO TOXIC SUBSTANCE 10 241 3.272e-05 0.0002889
528 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 13 406 3.361e-05 0.0002962
529 REGULATION OF ORGAN MORPHOGENESIS 10 242 3.389e-05 0.0002981
530 POSITIVE REGULATION OF CHROMOSOME ORGANIZATION 8 150 3.529e-05 0.0003098
531 NEURON MIGRATION 7 110 3.573e-05 0.0003131
532 PALLIUM DEVELOPMENT 8 153 4.065e-05 0.0003555
533 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 18 740 4.16e-05 0.0003631
534 POSITIVE REGULATION OF RECEPTOR INTERNALIZATION 4 24 4.173e-05 0.0003636
535 ORGANOPHOSPHATE METABOLIC PROCESS 20 885 4.299e-05 0.0003739
536 REGULATION OF HORMONE LEVELS 14 478 4.413e-05 0.0003831
537 POSITIVE REGULATION OF ENDOCYTOSIS 7 114 4.495e-05 0.0003888
538 REGULATION OF EMBRYONIC DEVELOPMENT 7 114 4.495e-05 0.0003888
539 BONE DEVELOPMENT 8 156 4.667e-05 0.0004029
540 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 7 115 4.754e-05 0.0004096
541 EPITHELIAL CELL APOPTOTIC PROCESS 4 25 4.936e-05 0.0004229
542 POSITIVE REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 4 25 4.936e-05 0.0004229
543 THYROID GLAND DEVELOPMENT 4 25 4.936e-05 0.0004229
544 RESPONSE TO PURINE CONTAINING COMPOUND 8 158 5.108e-05 0.0004369
545 CELLULAR RESPONSE TO HORMONE STIMULUS 15 552 5.5e-05 0.0004696
546 REGULATION OF FIBROBLAST PROLIFERATION 6 81 5.604e-05 0.0004775
547 LYMPHOCYTE HOMEOSTASIS 5 50 5.645e-05 0.0004785
548 RESPONSE TO PROGESTERONE 5 50 5.645e-05 0.0004785
549 REGULATION OF TUMOR NECROSIS FACTOR MEDIATED SIGNALING PATHWAY 5 50 5.645e-05 0.0004785
550 POSITIVE REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 5 51 6.218e-05 0.000525
551 REGULATION OF NEUROTRANSMITTER SECRETION 5 51 6.218e-05 0.000525
552 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 12 372 6.325e-05 0.0005331
553 POSITIVE REGULATION OF HEMOPOIESIS 8 163 6.366e-05 0.0005356
554 HAIR CYCLE 6 83 6.429e-05 0.0005381
555 EMBRYONIC PLACENTA DEVELOPMENT 6 83 6.429e-05 0.0005381
556 MOLTING CYCLE 6 83 6.429e-05 0.0005381
557 REGULATION OF PROTEIN KINASE B SIGNALING 7 121 6.573e-05 0.0005491
558 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 10 262 6.61e-05 0.0005502
559 POSITIVE REGULATION OF PROTEIN SECRETION 9 211 6.604e-05 0.0005502
560 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 4 27 6.76e-05 0.0005607
561 REGULATION OF FATTY ACID TRANSPORT 4 27 6.76e-05 0.0005607
562 NEGATIVE REGULATION OF ERK1 AND ERK2 CASCADE 5 52 6.833e-05 0.0005648
563 REGULATION OF PROTEIN COMPLEX ASSEMBLY 12 375 6.828e-05 0.0005648
564 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 6 84 6.877e-05 0.0005674
565 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 7 122 6.926e-05 0.0005704
566 RESPONSE TO ACID CHEMICAL 11 319 7.12e-05 0.0005853
567 REGULATION OF ADAPTIVE IMMUNE RESPONSE 7 123 7.293e-05 0.0005964
568 POSITIVE REGULATION OF MITOTIC CELL CYCLE 7 123 7.293e-05 0.0005964
569 ENDOCRINE SYSTEM DEVELOPMENT 7 123 7.293e-05 0.0005964
570 REGULATION OF CYTOSKELETON ORGANIZATION 14 502 7.459e-05 0.0006089
571 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 5 53 7.495e-05 0.0006097
572 POSITIVE REGULATION OF FIBROBLAST PROLIFERATION 5 53 7.495e-05 0.0006097
573 POSITIVE REGULATION OF LEUKOCYTE APOPTOTIC PROCESS 4 28 7.836e-05 0.0006339
574 NECROTIC CELL DEATH 4 28 7.836e-05 0.0006339
575 REGULATION OF FIBROBLAST MIGRATION 4 28 7.836e-05 0.0006339
576 REGULATION OF HEART RATE 6 86 7.847e-05 0.0006339
577 REGULATION OF AXONOGENESIS 8 168 7.871e-05 0.0006347
578 POSITIVE REGULATION OF HOMEOSTATIC PROCESS 9 216 7.906e-05 0.0006364
579 KIDNEY EPITHELIUM DEVELOPMENT 7 125 8.076e-05 0.000649
580 CELL CYCLE PROCESS 22 1081 8.274e-05 0.0006638
581 RESPONSE TO ESTROGEN 9 218 8.483e-05 0.0006794
582 GLUCOSE HOMEOSTASIS 8 170 8.55e-05 0.0006824
583 CARBOHYDRATE HOMEOSTASIS 8 170 8.55e-05 0.0006824
584 NEUROLOGICAL SYSTEM PROCESS 24 1242 8.586e-05 0.0006841
585 POSITIVE REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 3 11 8.666e-05 0.0006881
586 POSITIVE REGULATION OF NFAT PROTEIN IMPORT INTO NUCLEUS 3 11 8.666e-05 0.0006881
587 TISSUE HOMEOSTASIS 8 171 8.908e-05 0.0007061
588 STEM CELL DIVISION 4 29 9.031e-05 0.0007135
589 CARDIAC MUSCLE CELL CONTRACTION 4 29 9.031e-05 0.0007135
590 REGULATION OF PROTEIN STABILITY 9 221 9.416e-05 0.0007426
591 EPITHELIAL CELL PROLIFERATION 6 89 9.504e-05 0.0007482
592 SMAD PROTEIN SIGNAL TRANSDUCTION 5 56 9.78e-05 0.0007674
593 NEURON NEURON SYNAPTIC TRANSMISSION 5 56 9.78e-05 0.0007674
594 NUCLEAR IMPORT 7 129 9.848e-05 0.0007715
595 MUSCLE TISSUE DEVELOPMENT 10 275 9.872e-05 0.000772
596 MESONEPHROS DEVELOPMENT 6 90 0.0001011 0.0007896
597 CATION TRANSPORT 18 796 0.0001054 0.0008217
598 REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 5 57 0.0001065 0.0008286
599 POSITIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 7 131 0.0001085 0.0008425
600 SECRETION 15 588 0.0001112 0.0008621
601 NEGATIVE REGULATION OF TRANSPORT 13 458 0.0001139 0.0008815
602 REGULATION OF MACROPHAGE CYTOKINE PRODUCTION 3 12 0.0001148 0.0008833
603 POSITIVE REGULATION OF SMAD PROTEIN IMPORT INTO NUCLEUS 3 12 0.0001148 0.0008833
604 I KAPPAB PHOSPHORYLATION 3 12 0.0001148 0.0008833
605 TRACHEA MORPHOGENESIS 3 12 0.0001148 0.0008833
606 POSITIVE REGULATION OF CYTOKINE BIOSYNTHETIC PROCESS 5 58 0.0001158 0.0008889
607 ADULT WALKING BEHAVIOR 4 31 0.0001181 0.0008995
608 POSITIVE REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 4 31 0.0001181 0.0008995
609 LIPOPOLYSACCHARIDE MEDIATED SIGNALING PATHWAY 4 31 0.0001181 0.0008995
610 POSITIVE REGULATION OF INTERLEUKIN 2 PRODUCTION 4 31 0.0001181 0.0008995
611 WALKING BEHAVIOR 4 31 0.0001181 0.0008995
612 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 27 1517 0.0001187 0.0009022
613 TELENCEPHALON DEVELOPMENT 9 228 0.0001193 0.0009057
614 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 6 93 0.0001213 0.0009181
615 REGULATION OF LIPID METABOLIC PROCESS 10 282 0.0001213 0.0009181
616 MESENCHYMAL CELL DIFFERENTIATION 7 134 0.000125 0.0009439
617 REGULATION OF GLIAL CELL DIFFERENTIATION 5 59 0.0001257 0.0009476
618 PATTERNING OF BLOOD VESSELS 4 32 0.0001341 0.00101
619 DIVALENT INORGANIC CATION HOMEOSTASIS 11 343 0.0001352 0.001016
620 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 5 60 0.0001362 0.00102
621 LEUKOCYTE HOMEOSTASIS 5 60 0.0001362 0.00102
622 RESPONSE TO KETONE 8 182 0.0001373 0.001027
623 MUSCLE CONTRACTION 9 233 0.0001406 0.00105
624 REGULATION OF MITOTIC CELL CYCLE 13 468 0.000141 0.001051
625 CARDIOCYTE DIFFERENTIATION 6 96 0.0001446 0.001076
626 NEURONAL STEM CELL DIVISION 3 13 0.0001484 0.001091
627 REGULATION OF PROSTAGLANDIN SECRETION 3 13 0.0001484 0.001091
628 REGULATION OF INTERLEUKIN 8 PRODUCTION 5 61 0.0001474 0.001091
629 HEPATOCYTE APOPTOTIC PROCESS 3 13 0.0001484 0.001091
630 REGULATION OF HISTONE PHOSPHORYLATION 3 13 0.0001484 0.001091
631 NEUROBLAST DIVISION 3 13 0.0001484 0.001091
632 POSITIVE REGULATION OF STEM CELL PROLIFERATION 5 61 0.0001474 0.001091
633 CELLULAR RESPONSE TO OXIDATIVE STRESS 8 184 0.000148 0.001091
634 PLACENTA DEVELOPMENT 7 138 0.0001501 0.001101
635 EMBRYONIC DIGESTIVE TRACT DEVELOPMENT 4 33 0.0001517 0.001108
636 SIGNAL TRANSDUCTION IN ABSENCE OF LIGAND 4 33 0.0001517 0.001108
637 EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 4 33 0.0001517 0.001108
638 CELLULAR RESPONSE TO CYTOKINE STIMULUS 15 606 0.0001546 0.001128
639 FOREBRAIN CELL MIGRATION 5 62 0.0001592 0.001158
640 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 5 62 0.0001592 0.001158
641 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 6 98 0.000162 0.001176
642 NON CANONICAL WNT SIGNALING PATHWAY 7 140 0.0001641 0.001189
643 POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 4 34 0.0001708 0.001236
644 REGULATION OF CARTILAGE DEVELOPMENT 5 63 0.0001718 0.001241
645 MYELOID CELL DIFFERENTIATION 8 189 0.0001779 0.001283
646 STEM CELL DIFFERENTIATION 8 190 0.0001845 0.001329
647 REGULATION OF NEUROTRANSMITTER TRANSPORT 5 64 0.0001851 0.001329
648 REGULATION OF PROTEIN ACETYLATION 5 64 0.0001851 0.001329
649 REGULATION OF RESPIRATORY BURST 3 14 0.0001877 0.001338
650 VASCULAR ENDOTHELIAL GROWTH FACTOR SIGNALING PATHWAY 3 14 0.0001877 0.001338
651 POSITIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 3 14 0.0001877 0.001338
652 RESPONSE TO LAMINAR FLUID SHEAR STRESS 3 14 0.0001877 0.001338
653 NEGATIVE REGULATION OF INTRACELLULAR TRANSPORT 7 143 0.0001871 0.001338
654 POSITIVE REGULATION OF CELL CELL ADHESION 9 243 0.0001926 0.00137
655 CALCIUM ION IMPORT 5 65 0.0001992 0.001415
656 SECRETION BY CELL 13 486 0.000204 0.001447
657 NEGATIVE REGULATION OF PEPTIDASE ACTIVITY 9 245 0.0002047 0.00145
658 NEGATIVE REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 5 66 0.0002141 0.001505
659 ACID SECRETION 5 66 0.0002141 0.001505
660 FOREBRAIN GENERATION OF NEURONS 5 66 0.0002141 0.001505
661 NEGATIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 5 66 0.0002141 0.001505
662 HEAD MORPHOGENESIS 4 36 0.0002141 0.001505
663 EAR DEVELOPMENT 8 195 0.0002202 0.001545
664 NEGATIVE REGULATION OF GENE EXPRESSION 26 1493 0.0002275 0.001594
665 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 5 67 0.0002299 0.001608
666 NEGATIVE REGULATION OF DENDRITE MORPHOGENESIS 3 15 0.0002332 0.001627
667 NEUROTROPHIN TRK RECEPTOR SIGNALING PATHWAY 3 15 0.0002332 0.001627
668 REGULATION OF RECEPTOR INTERNALIZATION 4 37 0.0002386 0.001662
669 REGULATION OF CELL JUNCTION ASSEMBLY 5 68 0.0002465 0.001707
670 MULTICELLULAR ORGANISMAL RESPONSE TO STRESS 5 68 0.0002465 0.001707
671 ORGAN GROWTH 5 68 0.0002465 0.001707
672 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 5 68 0.0002465 0.001707
673 RESPONSE TO STEROID HORMONE 13 497 0.0002533 0.001751
674 INTRACELLULAR PROTEIN TRANSPORT 17 781 0.0002587 0.001786
675 PROTEIN LOCALIZATION TO CELL PERIPHERY 7 151 0.0002613 0.001801
676 REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 4 38 0.0002649 0.001824
677 RESPONSE TO OXYGEN LEVELS 10 311 0.0002675 0.001838
678 REGULATION OF MUSCLE CELL DIFFERENTIATION 7 152 0.000272 0.001867
679 REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 6 108 0.0002752 0.001886
680 REGULATION OF SMAD PROTEIN IMPORT INTO NUCLEUS 3 16 0.0002853 0.001941
681 CARDIAC MYOFIBRIL ASSEMBLY 3 16 0.0002853 0.001941
682 POSITIVE REGULATION OF TELOMERE CAPPING 3 16 0.0002853 0.001941
683 REGULATION OF INCLUSION BODY ASSEMBLY 3 16 0.0002853 0.001941
684 BRANCHING INVOLVED IN SALIVARY GLAND MORPHOGENESIS 3 16 0.0002853 0.001941
685 REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION 8 203 0.000289 0.001959
686 REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 6 109 0.0002892 0.001959
687 RESPONSE TO HYDROGEN PEROXIDE 6 109 0.0002892 0.001959
688 ASTROCYTE DIFFERENTIATION 4 39 0.0002933 0.001981
689 EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 4 39 0.0002933 0.001981
690 POSITIVE REGULATION OF PEPTIDASE ACTIVITY 7 154 0.0002946 0.001986
691 PROTEIN LOCALIZATION TO MEMBRANE 11 376 0.0002984 0.00201
692 FORMATION OF PRIMARY GERM LAYER 6 110 0.0003039 0.002043
693 PROTEIN IMPORT 7 155 0.0003064 0.002054
694 GASTRULATION 7 155 0.0003064 0.002054
695 NEURON PROJECTION GUIDANCE 8 205 0.0003087 0.002067
696 CELLULAR RESPONSE TO INORGANIC SUBSTANCE 7 156 0.0003186 0.002124
697 REGULATION OF LEUKOCYTE MEDIATED IMMUNITY 7 156 0.0003186 0.002124
698 PROTEIN LOCALIZATION TO NUCLEUS 7 156 0.0003186 0.002124
699 REGULATION OF MEIOTIC CELL CYCLE 4 40 0.0003238 0.002156
700 POSITIVE REGULATION OF PROTEIN BINDING 5 73 0.0003436 0.002276
701 REGULATION OF NFAT PROTEIN IMPORT INTO NUCLEUS 3 17 0.0003444 0.002276
702 BRANCH ELONGATION OF AN EPITHELIUM 3 17 0.0003444 0.002276
703 PHOSPHATIDYLGLYCEROL ACYL CHAIN REMODELING 3 17 0.0003444 0.002276
704 POSITIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 3 17 0.0003444 0.002276
705 REGULATION OF STEM CELL DIFFERENTIATION 6 113 0.0003513 0.002318
706 NEGATIVE REGULATION OF STRESS ACTIVATED MAPK CASCADE 4 41 0.0003565 0.002347
707 NEGATIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 4 41 0.0003565 0.002347
708 REGULATION OF LYMPHOCYTE MEDIATED IMMUNITY 6 114 0.0003683 0.00242
709 ORGANOPHOSPHATE BIOSYNTHETIC PROCESS 12 450 0.0003691 0.002422
710 NEPHRON DEVELOPMENT 6 115 0.0003859 0.002526
711 RESPONSE TO CALCIUM ION 6 115 0.0003859 0.002526
712 HEART MORPHOGENESIS 8 212 0.0003865 0.002526
713 NEGATIVE REGULATION OF PROTEOLYSIS 10 329 0.0004171 0.002722
714 MAMMARY GLAND DEVELOPMENT 6 117 0.0004232 0.002758
715 CEREBRAL CORTEX CELL MIGRATION 4 43 0.000429 0.002792
716 SINGLE ORGANISM CELL ADHESION 12 459 0.0004405 0.002863
717 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 7 166 0.0004634 0.003007
718 ION TRANSMEMBRANE TRANSPORT 17 822 0.0004654 0.003016
719 REGULATION OF RECEPTOR MEDIATED ENDOCYTOSIS 5 78 0.0004672 0.003024
720 BODY MORPHOGENESIS 4 44 0.0004689 0.00303
721 NEGATIVE REGULATION OF HYDROLASE ACTIVITY 11 397 0.0004717 0.003044
722 REGULATION OF ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLE PROPIONATE SELECTIVE GLUTAMATE RECEPTOR ACTIVITY 3 19 0.0004848 0.00312
723 POSITIVE REGULATION OF PROTEIN EXPORT FROM NUCLEUS 3 19 0.0004848 0.00312
724 DENDRITE DEVELOPMENT 5 79 0.0004955 0.003184
725 INTRACELLULAR RECEPTOR SIGNALING PATHWAY 7 168 0.0004978 0.003195
726 NEGATIVE REGULATION OF IMMUNE RESPONSE 6 121 0.0005062 0.003244
727 ENDOCHONDRAL BONE MORPHOGENESIS 4 45 0.0005113 0.003273
728 ADULT LOCOMOTORY BEHAVIOR 5 80 0.000525 0.003356
729 NEGATIVE REGULATION OF CELL DIFFERENTIATION 14 609 0.0005392 0.003442
730 REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 9 280 0.0005434 0.003463
731 INTRASPECIES INTERACTION BETWEEN ORGANISMS 4 46 0.0005564 0.003527
732 POSITIVE REGULATION OF MYELOID CELL DIFFERENTIATION 5 81 0.0005559 0.003527
733 SOCIAL BEHAVIOR 4 46 0.0005564 0.003527
734 POSITIVE REGULATION OF PROTEIN KINASE B SIGNALING 5 81 0.0005559 0.003527
735 EMBRYONIC HEMOPOIESIS 3 20 0.0005669 0.00357
736 REGULATION OF ICOSANOID SECRETION 3 20 0.0005669 0.00357
737 REGULATION OF SMOOTH MUSCLE CELL DIFFERENTIATION 3 20 0.0005669 0.00357
738 MICROVILLUS ORGANIZATION 3 20 0.0005669 0.00357
739 MYELOID DENDRITIC CELL DIFFERENTIATION 3 20 0.0005669 0.00357
740 KIDNEY MORPHOGENESIS 5 82 0.0005881 0.003698
741 POSITIVE REGULATION OF RECEPTOR MEDIATED ENDOCYTOSIS 4 47 0.0006043 0.00379
742 MUSCLE FIBER DEVELOPMENT 4 47 0.0006043 0.00379
743 ANATOMICAL STRUCTURE HOMEOSTASIS 9 285 0.0006168 0.003863
744 NIK NF KAPPAB SIGNALING 5 83 0.0006217 0.003888
745 NECROPTOTIC PROCESS 3 21 0.0006574 0.004073
746 POSITIVE REGULATION OF MUSCLE CELL DIFFERENTIATION 5 84 0.0006567 0.004073
747 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 4 48 0.0006551 0.004073
748 NEGATIVE REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 3 21 0.0006574 0.004073
749 BONE RESORPTION 3 21 0.0006574 0.004073
750 REGULATION OF INTERLEUKIN 2 PRODUCTION 4 48 0.0006551 0.004073
751 POSITIVE REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 4 48 0.0006551 0.004073
752 LEUKOCYTE ACTIVATION 11 414 0.0006676 0.004131
753 HEPATICOBILIARY SYSTEM DEVELOPMENT 6 128 0.0006814 0.004211
754 PALATE DEVELOPMENT 5 85 0.0006931 0.004272
755 POSITIVE REGULATION OF CHROMATIN MODIFICATION 5 85 0.0006931 0.004272
756 REGULATION OF OSSIFICATION 7 178 0.0007019 0.00432
757 CELLULAR RESPONSE TO CALCIUM ION 4 49 0.0007087 0.004356
758 ION TRANSPORT 22 1262 0.000712 0.00437
759 LEUKOCYTE DIFFERENTIATION 9 292 0.0007331 0.004494
760 NEGATIVE REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE 3 22 0.0007566 0.004614
761 SYNAPTIC TRANSMISSION GLUTAMATERGIC 3 22 0.0007566 0.004614
762 REGULATION OF TELOMERE CAPPING 3 22 0.0007566 0.004614
763 REGULATION OF CELL CYCLE PROCESS 13 558 0.0007537 0.004614
764 REGULATION OF ORGANIC ACID TRANSPORT 4 50 0.0007655 0.004644
765 REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 4 50 0.0007655 0.004644
766 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 4 50 0.0007655 0.004644
767 POSITIVE REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 4 50 0.0007655 0.004644
768 PROTEIN STABILIZATION 6 131 0.0007694 0.004662
769 LOCOMOTORY BEHAVIOR 7 181 0.0007745 0.004686
770 NEGATIVE REGULATION OF GROWTH 8 236 0.0007827 0.00473
771 POSITIVE REGULATION OF MITOTIC NUCLEAR DIVISION 4 51 0.0008253 0.004968
772 ARTERY MORPHOGENESIS 4 51 0.0008253 0.004968
773 REGULATION OF INTERLEUKIN 12 PRODUCTION 4 51 0.0008253 0.004968
774 SENSORY ORGAN MORPHOGENESIS 8 239 0.0008495 0.005107
775 ESTABLISHMENT OF PROTEIN LOCALIZATION TO ORGANELLE 10 361 0.0008538 0.005123
776 EPITHELIAL CELL DIFFERENTIATION 12 495 0.0008544 0.005123
777 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 3 23 0.0008649 0.005166
778 PHOSPHATIDYLETHANOLAMINE ACYL CHAIN REMODELING 3 23 0.0008649 0.005166
779 POSITIVE REGULATION OF COLLAGEN METABOLIC PROCESS 3 23 0.0008649 0.005166
780 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 6 134 0.000866 0.005166
781 RESPONSE TO ALCOHOL 10 362 0.0008719 0.005195
782 REGULATION OF T CELL MEDIATED IMMUNITY 4 52 0.0008884 0.005286
783 REGULATION OF GLIOGENESIS 5 90 0.0008985 0.005339
784 NEGATIVE REGULATION OF CELL DEVELOPMENT 9 303 0.0009515 0.005638
785 MAMMARY GLAND EPITHELIUM DEVELOPMENT 4 53 0.0009548 0.005638
786 REGULATION OF NITRIC OXIDE BIOSYNTHETIC PROCESS 4 53 0.0009548 0.005638
787 CYTOSOLIC CALCIUM ION TRANSPORT 4 53 0.0009548 0.005638
788 NEGATIVE REGULATION OF EPITHELIAL CELL MIGRATION 4 53 0.0009548 0.005638
789 NEGATIVE REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 3 24 0.0009825 0.005787
790 RESPONSE TO STEROL 3 24 0.0009825 0.005787
791 ION HOMEOSTASIS 13 576 0.001007 0.005924
792 NEGATIVE REGULATION OF REPRODUCTIVE PROCESS 4 54 0.001025 0.006012
793 B CELL RECEPTOR SIGNALING PATHWAY 4 54 0.001025 0.006012
794 REGULATION OF NEUROTRANSMITTER LEVELS 7 190 0.001029 0.006028
795 RESPONSE TO VIRUS 8 247 0.00105 0.006146
796 CARDIAC MUSCLE TISSUE DEVELOPMENT 6 140 0.001087 0.006355
797 NEURAL TUBE FORMATION 5 94 0.001093 0.006381
798 REGULATION OF KIDNEY DEVELOPMENT 4 55 0.001098 0.006394
799 REGULATION OF POSTSYNAPTIC MEMBRANE POTENTIAL 4 55 0.001098 0.006394
800 RESPONSE TO EXTRACELLULAR STIMULUS 11 441 0.001115 0.006487
801 DEVELOPMENTAL MATURATION 7 193 0.001127 0.006544
802 REGULATION OF ACTIN FILAMENT BASED PROCESS 9 312 0.001167 0.006771
803 EPITHELIAL TO MESENCHYMAL TRANSITION 4 56 0.001175 0.006799
804 OUTFLOW TRACT MORPHOGENESIS 4 56 0.001175 0.006799
805 MYELOID LEUKOCYTE DIFFERENTIATION 5 96 0.001201 0.006934
806 FEMALE GAMETE GENERATION 5 96 0.001201 0.006934
807 DEVELOPMENTAL PROGRAMMED CELL DEATH 3 26 0.001247 0.007119
808 REPLACEMENT OSSIFICATION 3 26 0.001247 0.007119
809 DEFENSE RESPONSE 21 1231 0.001242 0.007119
810 NEGATIVE REGULATION OF EMBRYONIC DEVELOPMENT 3 26 0.001247 0.007119
811 ENDOCHONDRAL OSSIFICATION 3 26 0.001247 0.007119
812 PHOSPHATIDYLCHOLINE ACYL CHAIN REMODELING 3 26 0.001247 0.007119
813 MYELOID DENDRITIC CELL ACTIVATION 3 26 0.001247 0.007119
814 POSITIVE REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION 3 26 0.001247 0.007119
815 REGULATION OF CELL FATE COMMITMENT 3 26 0.001247 0.007119
816 MEMBRANE ORGANIZATION 17 899 0.001251 0.007134
817 ENDOTHELIAL CELL MIGRATION 4 57 0.001256 0.007141
818 MYOTUBE DIFFERENTIATION 4 57 0.001256 0.007141
819 REGULATION OF RESPONSE TO CYTOKINE STIMULUS 6 144 0.001257 0.007141
820 POSTTRANSCRIPTIONAL REGULATION OF GENE EXPRESSION 11 448 0.001265 0.007179
821 POSITIVE REGULATION OF PROTEIN COMPLEX ASSEMBLY 7 197 0.001268 0.007188
822 MEMORY 5 98 0.001317 0.007446
823 MYELOID LEUKOCYTE ACTIVATION 5 98 0.001317 0.007446
824 CYTOKINE MEDIATED SIGNALING PATHWAY 11 452 0.001358 0.007668
825 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 5 99 0.001378 0.007763
826 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 5 99 0.001378 0.007763
827 EXCITATORY POSTSYNAPTIC POTENTIAL 3 27 0.001394 0.007807
828 POSITIVE REGULATION OF NEUTROPHIL MIGRATION 3 27 0.001394 0.007807
829 POSITIVE REGULATION OF FILOPODIUM ASSEMBLY 3 27 0.001394 0.007807
830 AXIS ELONGATION 3 27 0.001394 0.007807
831 REGULATION OF NEUTROPHIL CHEMOTAXIS 3 27 0.001394 0.007807
832 POSITIVE REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 4 59 0.001428 0.007968
833 VASCULOGENESIS 4 59 0.001428 0.007968
834 REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 4 59 0.001428 0.007968
835 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 5 100 0.001441 0.008011
836 POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 5 100 0.001441 0.008011
837 LIMBIC SYSTEM DEVELOPMENT 5 100 0.001441 0.008011
838 CELLULAR RESPONSE TO LIPID 11 457 0.001482 0.008227
839 NEURAL TUBE DEVELOPMENT 6 149 0.001497 0.008302
840 PLASMA MEMBRANE ORGANIZATION 7 203 0.001507 0.008336
841 REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 5 101 0.001506 0.008336
842 STEM CELL PROLIFERATION 4 60 0.001521 0.008393
843 REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 4 60 0.001521 0.008393
844 POSITIVE REGULATION OF SUBSTRATE ADHESION DEPENDENT CELL SPREADING 3 28 0.001552 0.008527
845 POSITIVE REGULATION OF TELOMERASE ACTIVITY 3 28 0.001552 0.008527
846 NEGATIVE REGULATION OF DENDRITE DEVELOPMENT 3 28 0.001552 0.008527
847 REGULATION OF SPROUTING ANGIOGENESIS 3 28 0.001552 0.008527
848 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 5 102 0.001573 0.008633
849 CELL PROJECTION ASSEMBLY 8 264 0.001602 0.008781
850 POSITIVE REGULATION OF CYCLASE ACTIVITY 4 61 0.001617 0.008851
851 REGULATION OF LEUKOCYTE PROLIFERATION 7 206 0.001638 0.008958
852 REGULATION OF CHROMATIN ORGANIZATION 6 152 0.001657 0.009048
853 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 7 207 0.001684 0.009187
854 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 11 465 0.001699 0.009245
855 ENDOMEMBRANE SYSTEM ORGANIZATION 11 465 0.001699 0.009245
856 EPIDERMIS MORPHOGENESIS 3 29 0.001721 0.009257
857 NEGATIVE REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE 3 29 0.001721 0.009257
858 REGULATION OF EXTRACELLULAR MATRIX ORGANIZATION 3 29 0.001721 0.009257
859 REGULATION OF HEART MORPHOGENESIS 3 29 0.001721 0.009257
860 RESPONSE TO PAIN 3 29 0.001721 0.009257
861 MUSCLE ADAPTATION 3 29 0.001721 0.009257
862 REGULATION OF SMOOTHENED SIGNALING PATHWAY 4 62 0.001717 0.009257
863 POSITIVE REGULATION OF NUCLEAR DIVISION 4 62 0.001717 0.009257
864 NEUROBLAST PROLIFERATION 3 29 0.001721 0.009257
865 CELLULAR RESPONSE TO REACTIVE OXYGEN SPECIES 5 104 0.001714 0.009257
866 LIPID BIOSYNTHETIC PROCESS 12 539 0.00176 0.009455
867 ODONTOGENESIS 5 105 0.001788 0.009598
868 TRANSMEMBRANE TRANSPORT 19 1098 0.001818 0.009745
869 RESPONSE TO OSMOTIC STRESS 4 63 0.001822 0.009757
NumGOOverlapSizeP ValueAdj. P Value
1 PROTEIN KINASE ACTIVITY 66 640 4.647e-55 4.317e-52
2 RECEPTOR SIGNALING PROTEIN SERINE THREONINE KINASE ACTIVITY 36 92 5.407e-52 2.512e-49
3 PROTEIN SERINE THREONINE KINASE ACTIVITY 54 445 3.284e-48 1.017e-45
4 KINASE ACTIVITY 66 842 2.863e-47 6.65e-45
5 RECEPTOR SIGNALING PROTEIN ACTIVITY 38 172 6.023e-44 1.119e-41
6 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 66 992 9.969e-43 1.543e-40
7 RIBONUCLEOTIDE BINDING 75 1860 3.84e-34 5.096e-32
8 ADENYL NUCLEOTIDE BINDING 65 1514 1.579e-30 1.833e-28
9 KINASE BINDING 43 606 3.413e-28 3.523e-26
10 ENZYME BINDING 62 1737 1.386e-24 1.288e-22
11 MAP KINASE KINASE KINASE ACTIVITY 13 22 2.366e-22 1.998e-20
12 SIGNAL TRANSDUCER ACTIVITY 57 1731 1.038e-20 8.033e-19
13 VOLTAGE GATED CALCIUM CHANNEL ACTIVITY 14 42 1.671e-19 1.194e-17
14 HIGH VOLTAGE GATED CALCIUM CHANNEL ACTIVITY 9 11 7.703e-18 5.112e-16
15 MAP KINASE PHOSPHATASE ACTIVITY 9 14 2.745e-16 1.7e-14
16 PROTEIN TYROSINE KINASE ACTIVITY 19 176 4.116e-16 2.39e-14
17 MOLECULAR FUNCTION REGULATOR 44 1353 1.45e-15 7.924e-14
18 PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 18 178 8.124e-15 4.193e-13
19 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 19 228 4.954e-14 2.422e-12
20 CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 15 128 1.732e-13 8.044e-12
21 GROWTH FACTOR ACTIVITY 16 160 3.214e-13 1.422e-11
22 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 12 70 4.669e-13 1.972e-11
23 MAGNESIUM ION BINDING 17 199 7.588e-13 3.065e-11
24 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 20 303 8.324e-13 3.222e-11
25 PROTEIN TYROSINE PHOSPHATASE ACTIVITY 13 103 2.866e-12 1.065e-10
26 VOLTAGE GATED CATION CHANNEL ACTIVITY 14 134 5.631e-12 2.012e-10
27 DIVALENT INORGANIC CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 15 167 8.718e-12 2.999e-10
28 PHOSPHATASE ACTIVITY 18 275 1.423e-11 4.721e-10
29 PROTEIN SERINE THREONINE TYROSINE KINASE ACTIVITY 9 39 2.437e-11 7.806e-10
30 FIBROBLAST GROWTH FACTOR RECEPTOR BINDING 8 28 4.887e-11 1.513e-09
31 GROWTH FACTOR RECEPTOR BINDING 13 129 5.243e-11 1.522e-09
32 RECEPTOR BINDING 39 1476 5.241e-11 1.522e-09
33 VOLTAGE GATED ION CHANNEL ACTIVITY 15 190 5.561e-11 1.566e-09
34 X1 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 9 43 6.304e-11 1.723e-09
35 PROTEIN TYROSINE SERINE THREONINE PHOSPHATASE ACTIVITY 9 45 9.768e-11 2.593e-09
36 PHOSPHATIDYLINOSITOL KINASE ACTIVITY 9 51 3.215e-10 8.296e-09
37 MAP KINASE ACTIVITY 6 14 8.183e-10 2.055e-08
38 PHOSPHORIC ESTER HYDROLASE ACTIVITY 18 368 1.619e-09 3.957e-08
39 MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE BINDING 6 18 4.922e-09 1.173e-07
40 GROWTH FACTOR BINDING 11 123 5.99e-09 1.391e-07
41 PROTEIN DIMERIZATION ACTIVITY 30 1149 1.736e-08 3.933e-07
42 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 9 81 2.232e-08 4.937e-07
43 CALCIUM DEPENDENT PROTEIN KINASE ACTIVITY 5 12 2.718e-08 5.627e-07
44 MAP KINASE KINASE ACTIVITY 5 12 2.718e-08 5.627e-07
45 CATION CHANNEL ACTIVITY 15 298 2.726e-08 5.627e-07
46 GATED CHANNEL ACTIVITY 15 325 8.52e-08 1.721e-06
47 KINASE ACTIVATOR ACTIVITY 7 62 7.691e-07 1.52e-05
48 HYDROLASE ACTIVITY ACTING ON ESTER BONDS 21 739 8.028e-07 1.554e-05
49 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 7 64 9.581e-07 1.817e-05
50 DIACYLGLYCEROL BINDING 4 11 1.409e-06 2.618e-05
51 PROTEIN HETERODIMERIZATION ACTIVITY 16 468 1.746e-06 3.18e-05
52 METAL ION TRANSMEMBRANE TRANSPORTER ACTIVITY 15 417 2.006e-06 3.585e-05
53 UBIQUITIN LIKE PROTEIN LIGASE BINDING 12 264 2.059e-06 3.609e-05
54 IDENTICAL PROTEIN BINDING 27 1209 2.117e-06 3.642e-05
55 HISTONE DEACETYLASE BINDING 8 105 2.56e-06 4.325e-05
56 CYTOKINE RECEPTOR BINDING 12 271 2.7e-06 4.479e-05
57 KINASE REGULATOR ACTIVITY 10 186 3.414e-06 5.565e-05
58 ENZYME REGULATOR ACTIVITY 23 959 4.136e-06 6.624e-05
59 PROTEIN DOMAIN SPECIFIC BINDING 18 624 4.234e-06 6.666e-05
60 HEPARIN BINDING 9 157 6.344e-06 9.822e-05
61 PASSIVE TRANSMEMBRANE TRANSPORTER ACTIVITY 15 464 7.32e-06 0.0001115
62 MITOGEN ACTIVATED PROTEIN KINASE KINASE BINDING 4 16 7.524e-06 0.0001127
63 GLYCOSAMINOGLYCAN BINDING 10 205 8.084e-06 0.0001192
64 ENZYME ACTIVATOR ACTIVITY 15 471 8.749e-06 0.000127
65 MACROMOLECULAR COMPLEX BINDING 28 1399 1.074e-05 0.0001534
66 PROTEIN SERINE THREONINE KINASE ACTIVATOR ACTIVITY 4 19 1.572e-05 0.0002179
67 HISTONE KINASE ACTIVITY 4 19 1.572e-05 0.0002179
68 SMAD BINDING 6 72 2.868e-05 0.0003918
69 PROTEIN HOMODIMERIZATION ACTIVITY 18 722 3.019e-05 0.0004037
70 TRANSCRIPTION FACTOR BINDING 15 524 3.042e-05 0.0004037
71 INORGANIC CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 15 527 3.248e-05 0.0004249
72 SCAFFOLD PROTEIN BINDING 5 45 3.365e-05 0.0004342
73 TRANSFORMING GROWTH FACTOR BETA RECEPTOR BINDING 5 50 5.645e-05 0.0007184
74 PROTEIN COMPLEX BINDING 20 935 9.156e-05 0.001149
75 CHANNEL REGULATOR ACTIVITY 7 131 0.0001085 0.001344
76 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 9 226 0.0001116 0.001364
77 PHOSPHOPROTEIN BINDING 5 60 0.0001362 0.001643
78 SULFUR COMPOUND BINDING 9 234 0.0001452 0.001729
79 PROTEIN SERINE THREONINE PHOSPHATASE ACTIVITY 5 64 0.0001851 0.002177
80 NEUROTROPHIN RECEPTOR BINDING 3 14 0.0001877 0.00218
81 CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 15 622 0.0002049 0.00235
82 GTPASE ACTIVITY 9 246 0.000211 0.00239
83 PLATELET DERIVED GROWTH FACTOR RECEPTOR BINDING 3 15 0.0002332 0.002611
84 TRANSFORMING GROWTH FACTOR BETA BINDING 3 16 0.0002853 0.003118
85 PROTEIN KINASE C ACTIVITY 3 16 0.0002853 0.003118
86 GTP DEPENDENT PROTEIN BINDING 3 17 0.0003444 0.00372
87 CYSTEINE TYPE ENDOPEPTIDASE REGULATOR ACTIVITY INVOLVED IN APOPTOTIC PROCESS 4 42 0.0003916 0.004181
88 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 10 328 0.0004073 0.004252
89 GUANYL NUCLEOTIDE BINDING 11 390 0.0004064 0.004252
90 ADRENERGIC RECEPTOR BINDING 3 19 0.0004848 0.005004
91 CALMODULIN BINDING 7 179 0.0007254 0.007406
92 R SMAD BINDING 3 23 0.0008649 0.008548
93 FIBROBLAST GROWTH FACTOR BINDING 3 23 0.0008649 0.008548
94 CYSTEINE TYPE ENDOPEPTIDASE INHIBITOR ACTIVITY INVOLVED IN APOPTOTIC PROCESS 3 23 0.0008649 0.008548
95 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC BINDING 5 90 0.0008985 0.008787
96 MITOGEN ACTIVATED PROTEIN KINASE BINDING 3 24 0.0009825 0.00941
97 PROTEIN PHOSPHORYLATED AMINO ACID BINDING 3 24 0.0009825 0.00941
NumGOOverlapSizeP ValueAdj. P Value
1 VOLTAGE GATED CALCIUM CHANNEL COMPLEX 16 40 1.16e-23 6.776e-21
2 CALCIUM CHANNEL COMPLEX 17 62 8.788e-22 2.566e-19
3 CATION CHANNEL COMPLEX 17 167 4.199e-14 8.175e-12
4 PLASMA MEMBRANE PROTEIN COMPLEX 26 510 1.035e-13 1.511e-11
5 SARCOLEMMA 12 125 5.234e-10 6.114e-08
6 TRANSPORTER COMPLEX 17 321 1.427e-09 1.389e-07
7 PROTEIN KINASE COMPLEX 10 90 3.602e-09 3.005e-07
8 MEMBRANE PROTEIN COMPLEX 29 1020 4.768e-09 3.481e-07
9 CELL SUBSTRATE JUNCTION 18 398 5.545e-09 3.598e-07
10 IKAPPAB KINASE COMPLEX 5 11 1.596e-08 9.323e-07
11 T TUBULE 7 45 7.982e-08 4.238e-06
12 SOMATODENDRITIC COMPARTMENT 21 650 9.756e-08 4.748e-06
13 ANCHORING JUNCTION 18 489 1.277e-07 5.736e-06
14 NEURON PROJECTION 25 942 2.337e-07 9.747e-06
15 PERINUCLEAR REGION OF CYTOPLASM 20 642 3.598e-07 1.401e-05
16 NEURON PART 29 1265 4.892e-07 1.786e-05
17 CYTOPLASMIC SIDE OF MEMBRANE 10 170 1.519e-06 5.217e-05
18 SIDE OF MEMBRANE 15 428 2.761e-06 8.957e-05
19 SYNAPSE 20 754 4.251e-06 0.0001307
20 EXCITATORY SYNAPSE 10 197 5.692e-06 0.0001662
21 CELL JUNCTION 25 1151 8.585e-06 0.0002279
22 CELL PROJECTION 33 1786 8.343e-06 0.0002279
23 CELL BODY 15 494 1.535e-05 0.0003899
24 DENDRITE 14 451 2.341e-05 0.0005697
25 TRANSFERASE COMPLEX TRANSFERRING PHOSPHORUS CONTAINING GROUPS 10 237 2.838e-05 0.0006629
26 I BAND 7 121 6.573e-05 0.001476
27 CD40 RECEPTOR COMPLEX 3 11 8.666e-05 0.001851
28 RECEPTOR COMPLEX 11 327 8.875e-05 0.001851
29 MEMBRANE MICRODOMAIN 10 288 0.0001441 0.002902
30 SYNAPSE PART 15 610 0.0001661 0.003233
31 INTRACELLULAR VESICLE 23 1259 0.0002767 0.005154
32 ACTIN FILAMENT 5 70 0.0002824 0.005154
33 POSTSYNAPSE 11 378 0.0003122 0.005525
34 PSEUDOPODIUM 3 17 0.0003444 0.005915
35 EXTRACELLULAR SPACE 24 1376 0.0003974 0.00663
36 MEMBRANE REGION 21 1134 0.0004353 0.007061

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04010_MAPK_signaling_pathway 165 268 0 0
2 hsa04014_Ras_signaling_pathway 61 236 2.232e-76 2.009e-74
3 hsa04722_Neurotrophin_signaling_pathway 35 127 3.282e-44 1.969e-42
4 hsa04912_GnRH_signaling_pathway 30 101 5.028e-39 2.262e-37
5 hsa04380_Osteoclast_differentiation 31 128 3.355e-37 1.208e-35
6 hsa04810_Regulation_of_actin_cytoskeleton 34 214 4.391e-34 1.175e-32
7 hsa04662_B_cell_receptor_signaling_pathway 25 75 4.57e-34 1.175e-32
8 hsa04664_Fc_epsilon_RI_signaling_pathway 25 79 2.113e-33 4.754e-32
9 hsa04151_PI3K_AKT_signaling_pathway 39 351 6.277e-33 1.255e-31
10 hsa04660_T_cell_receptor_signaling_pathway 27 108 7.253e-33 1.306e-31
11 hsa04370_VEGF_signaling_pathway 23 76 2.884e-30 4.72e-29
12 hsa04620_Toll.like_receptor_signaling_pathway 24 102 1.389e-28 2.084e-27
13 hsa04012_ErbB_signaling_pathway 22 87 4.935e-27 6.833e-26
14 hsa04720_Long.term_potentiation 20 70 7.424e-26 9.545e-25
15 hsa04510_Focal_adhesion 26 200 8.038e-24 9.646e-23
16 hsa04062_Chemokine_signaling_pathway 25 189 4.004e-23 4.505e-22
17 hsa04210_Apoptosis 19 89 6.175e-22 6.538e-21
18 hsa04914_Progesterone.mediated_oocyte_maturation 18 87 1.433e-20 1.433e-19
19 hsa04540_Gap_junction 18 90 2.763e-20 2.618e-19
20 hsa04310_Wnt_signaling_pathway 21 151 5.002e-20 4.502e-19
21 hsa04650_Natural_killer_cell_mediated_cytotoxicity 20 136 1.285e-19 1.101e-18
22 hsa04910_Insulin_signaling_pathway 19 138 3.949e-18 3.231e-17
23 hsa04020_Calcium_signaling_pathway 19 177 4.578e-16 3.583e-15
24 hsa04730_Long.term_depression 13 70 1.606e-14 1.205e-13
25 hsa04270_Vascular_smooth_muscle_contraction 15 116 3.926e-14 2.827e-13
26 hsa04621_NOD.like_receptor_signaling_pathway 12 59 5.312e-14 3.677e-13
27 hsa04144_Endocytosis 16 203 1.266e-11 8.439e-11
28 hsa04360_Axon_guidance 13 130 5.784e-11 3.718e-10
29 hsa04114_Oocyte_meiosis 12 114 1.774e-10 1.101e-09
30 hsa04622_RIG.I.like_receptor_signaling_pathway 10 71 3.325e-10 1.995e-09
31 hsa04666_Fc_gamma_R.mediated_phagocytosis 11 95 3.701e-10 2.149e-09
32 hsa04520_Adherens_junction 10 73 4.412e-10 2.482e-09
33 hsa04916_Melanogenesis 11 101 7.22e-10 3.938e-09
34 hsa04260_Cardiac_muscle_contraction 10 77 7.572e-10 4.009e-09
35 hsa04920_Adipocytokine_signaling_pathway 9 68 4.62e-09 2.376e-08
36 hsa04320_Dorso.ventral_axis_formation 6 25 4.477e-08 2.238e-07
37 hsa04530_Tight_junction 10 133 1.568e-07 7.629e-07
38 hsa04150_mTOR_signaling_pathway 7 52 2.242e-07 1.062e-06
39 hsa04972_Pancreatic_secretion 8 101 1.908e-06 8.807e-06
40 hsa04350_TGF.beta_signaling_pathway 7 85 6.585e-06 2.963e-05
41 hsa04141_Protein_processing_in_endoplasmic_reticulum 9 168 1.097e-05 4.793e-05
42 hsa04110_Cell_cycle 8 128 1.118e-05 4.793e-05
43 hsa04960_Aldosterone.regulated_sodium_reabsorption 5 42 2.39e-05 0.0001001
44 hsa04971_Gastric_acid_secretion 6 74 3.354e-05 0.0001372
45 hsa04390_Hippo_signaling_pathway 8 154 4.258e-05 0.0001703
46 hsa04670_Leukocyte_transendothelial_migration 7 117 5.307e-05 0.0002077
47 hsa04742_Taste_transduction 5 52 6.833e-05 0.0002617
48 hsa04970_Salivary_secretion 6 89 9.504e-05 0.0003564
49 hsa04623_Cytosolic_DNA.sensing_pathway 5 56 9.78e-05 0.0003593
50 hsa04973_Carbohydrate_digestion_and_absorption 4 44 0.0004689 0.001688
51 hsa00592_alpha.Linolenic_acid_metabolism 3 20 0.0005669 0.002001
52 hsa00591_Linoleic_acid_metabolism 3 30 0.001901 0.006579
53 hsa04115_p53_signaling_pathway 4 69 0.002546 0.008645
54 hsa00565_Ether_lipid_metabolism 3 36 0.003224 0.01075
55 hsa04612_Antigen_processing_and_presentation 4 78 0.003967 0.01298
56 hsa04962_Vasopressin.regulated_water_reabsorption 3 44 0.005699 0.01832
57 hsa04640_Hematopoietic_cell_lineage 4 88 0.006086 0.01922
58 hsa04975_Fat_digestion_and_absorption 3 46 0.006454 0.02003
59 hsa04630_Jak.STAT_signaling_pathway 5 155 0.009324 0.02845
60 hsa04340_Hedgehog_signaling_pathway 3 56 0.0111 0.03331
61 hsa00590_Arachidonic_acid_metabolism 3 59 0.01279 0.03774
62 hsa04976_Bile_secretion 3 71 0.02093 0.06078
63 hsa03040_Spliceosome 4 128 0.02165 0.06185
64 hsa04744_Phototransduction 2 29 0.02374 0.06677
65 hsa04070_Phosphatidylinositol_signaling_system 3 78 0.02673 0.07403
66 hsa00564_Glycerophospholipid_metabolism 3 80 0.02853 0.07781
67 hsa04672_Intestinal_immune_network_for_IgA_production 2 49 0.06183 0.1661
68 hsa04145_Phagosome 2 156 0.3694 0.9778
69 hsa04740_Olfactory_transduction 4 388 0.3983 1

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1

PCA3

hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-16-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-182-5p;hsa-miR-200c-5p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-32-3p;hsa-miR-369-3p;hsa-miR-370-3p;hsa-miR-590-3p;hsa-miR-654-5p;hsa-miR-93-3p;hsa-miR-96-5p 18 CACNB2 Sponge network -2.778 8.0E-5 -2.086 1.0E-5 0.684
2

PCA3

hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-miR-107;hsa-miR-1254;hsa-miR-1271-5p;hsa-miR-148b-5p;hsa-miR-149-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-320b;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-589-3p;hsa-miR-93-3p;hsa-miR-944;hsa-miR-96-5p 21 CACNA1C Sponge network -2.778 8.0E-5 -1.469 0.0005 0.509
3

PCA3

hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-1-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-18a-3p;hsa-miR-20a-5p;hsa-miR-27a-3p;hsa-miR-320b;hsa-miR-33a-3p;hsa-miR-3662;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-616-5p;hsa-miR-944 20 FGF7 Sponge network -2.778 8.0E-5 -1.56 0.00499 0.493
4

MEG3

hsa-miR-107;hsa-miR-1254;hsa-miR-1976;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-320b;hsa-miR-378a-5p;hsa-miR-429;hsa-miR-577;hsa-miR-7-1-3p;hsa-miR-93-3p;hsa-miR-96-5p 15 CACNA1C Sponge network -1.645 0.00049 -1.469 0.0005 0.469
5

RFPL1S

hsa-miR-106b-5p;hsa-miR-107;hsa-miR-17-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-320b;hsa-miR-33a-3p;hsa-miR-362-3p;hsa-miR-501-3p;hsa-miR-502-3p;hsa-miR-505-3p 11 AKT3 Sponge network -0.223 0.70704 -0.749 0.06936 0.466
6

MEG3

hsa-miR-107;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-1-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-18a-3p;hsa-miR-20a-5p;hsa-miR-31-5p;hsa-miR-320b;hsa-miR-33a-3p;hsa-miR-3662;hsa-miR-429;hsa-miR-577;hsa-miR-616-5p;hsa-miR-7-1-3p 16 FGF7 Sponge network -1.645 0.00049 -1.56 0.00499 0.458
7

MEG3

hsa-miR-130b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-335-3p;hsa-miR-33a-3p;hsa-miR-429;hsa-miR-652-3p;hsa-miR-7-1-3p;hsa-miR-96-5p 11 MRAS Sponge network -1.645 0.00049 -0.939 0.01023 0.445
8

CASC2

hsa-miR-183-5p;hsa-miR-193b-3p;hsa-miR-193b-5p;hsa-miR-218-5p;hsa-miR-22-5p;hsa-miR-224-5p;hsa-miR-2355-3p;hsa-miR-24-2-5p;hsa-miR-369-3p;hsa-miR-452-5p;hsa-miR-654-3p;hsa-miR-944 12 PRKCA Sponge network -0.561 0.05962 -0.525 0.15685 0.436
9

PLAC4

hsa-miR-127-5p;hsa-miR-149-5p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-331-3p;hsa-miR-511-5p;hsa-miR-582-3p;hsa-miR-940;hsa-miR-944 12 RAPGEF2 Sponge network -0.563 0.27163 -0.748 0.00078 0.432
10

CASC2

hsa-miR-127-5p;hsa-miR-149-5p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-331-3p;hsa-miR-369-3p;hsa-miR-511-5p;hsa-miR-940;hsa-miR-944 12 RAPGEF2 Sponge network -0.561 0.05962 -0.748 0.00078 0.417
11

PCA3

hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-miR-103a-3p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-15b-3p;hsa-miR-15b-5p;hsa-miR-16-1-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-186-5p;hsa-miR-19b-1-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-330-3p;hsa-miR-335-5p;hsa-miR-3662;hsa-miR-3682-3p;hsa-miR-424-5p;hsa-miR-589-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-93-3p 28 FGF2 Sponge network -2.778 8.0E-5 -1.879 0.00013 0.416
12

MEG3

hsa-miR-103a-3p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-15b-3p;hsa-miR-15b-5p;hsa-miR-16-1-3p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-19b-1-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-330-3p;hsa-miR-335-3p;hsa-miR-335-5p;hsa-miR-3662;hsa-miR-429;hsa-miR-577;hsa-miR-93-3p 19 FGF2 Sponge network -1.645 0.00049 -1.879 0.00013 0.415
13

MEG3

hsa-miR-106b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-330-3p;hsa-miR-335-3p;hsa-miR-577 11 FGFR1 Sponge network -1.645 0.00049 -1.499 0.00051 0.412
14

MEG3

hsa-miR-106b-5p;hsa-miR-107;hsa-miR-1254;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-20a-5p;hsa-miR-330-3p;hsa-miR-331-3p;hsa-miR-429;hsa-miR-7-1-3p;hsa-miR-93-5p;hsa-miR-96-5p 16 MAP3K3 Sponge network -1.645 0.00049 -0.635 0.00017 0.409
15

PCA3

hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-103a-2-5p;hsa-miR-1296-5p;hsa-miR-130b-5p;hsa-miR-135b-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-18a-3p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200c-5p;hsa-miR-224-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-32-3p;hsa-miR-320b;hsa-miR-324-3p;hsa-miR-331-5p;hsa-miR-33a-3p;hsa-miR-33b-5p;hsa-miR-3613-5p;hsa-miR-425-5p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-744-3p;hsa-miR-940;hsa-miR-96-5p 31 MEF2C Sponge network -2.778 8.0E-5 -0.552 0.096 0.403
16

MALAT1

hsa-miR-106b-5p;hsa-miR-149-5p;hsa-miR-15b-5p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-331-3p;hsa-miR-379-5p 10 RAPGEF2 Sponge network -1.099 0.0005 -0.748 0.00078 0.398
17

KCNQ1OT1

hsa-let-7a-2-3p;hsa-let-7b-5p;hsa-miR-152-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-28-5p 11 NLK Sponge network -0.725 0.08874 0.087 0.60941 0.392
18

MEG3

hsa-miR-130b-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-18a-3p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-200c-5p;hsa-miR-320b;hsa-miR-324-3p;hsa-miR-331-5p;hsa-miR-335-3p;hsa-miR-33a-3p;hsa-miR-429;hsa-miR-550a-3p;hsa-miR-744-3p;hsa-miR-96-5p 17 MEF2C Sponge network -1.645 0.00049 -0.552 0.096 0.39
19

PCA3

hsa-miR-141-5p;hsa-miR-16-2-3p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-23a-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-452-3p;hsa-miR-589-3p;hsa-miR-589-5p;hsa-miR-590-5p;hsa-miR-616-5p 12 PRKCB Sponge network -2.778 8.0E-5 -1.403 0.00367 0.387
20

PCA3

hsa-miR-106b-5p;hsa-miR-107;hsa-miR-1254;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-182-5p;hsa-miR-185-3p;hsa-miR-188-5p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-221-5p;hsa-miR-330-3p;hsa-miR-331-3p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-424-5p;hsa-miR-93-5p;hsa-miR-96-5p 23 MAP3K3 Sponge network -2.778 8.0E-5 -0.635 0.00017 0.384
21

DGCR5

hsa-miR-107;hsa-miR-140-3p;hsa-miR-148a-5p;hsa-miR-30d-3p;hsa-miR-30d-5p;hsa-miR-326;hsa-miR-338-3p;hsa-miR-362-5p;hsa-miR-501-5p;hsa-miR-577 10 NTRK2 Sponge network 1.383 0.01835 0.129 0.90432 0.38
22

MEG3

hsa-let-7g-3p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-196a-5p;hsa-miR-196b-5p;hsa-miR-20a-5p;hsa-miR-219a-5p;hsa-miR-335-3p;hsa-miR-93-5p;hsa-miR-96-5p 14 PDGFRA Sponge network -1.645 0.00049 -1.161 0.00469 0.38
23

PLAC4

hsa-miR-127-5p;hsa-miR-1271-5p;hsa-miR-149-5p;hsa-miR-183-5p;hsa-miR-205-5p;hsa-miR-224-3p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-34c-3p;hsa-miR-708-5p;hsa-miR-940;hsa-miR-944 15 MAP3K13 Sponge network -0.563 0.27163 0.158 0.68798 0.377
24 FAM66C hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-miR-135b-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-18a-3p;hsa-miR-18a-5p;hsa-miR-27a-3p;hsa-miR-3613-5p;hsa-miR-429;hsa-miR-590-3p;hsa-miR-590-5p 12 MEF2C Sponge network -0.353 0.40349 -0.552 0.096 0.375
25

KCNQ1OT1

hsa-miR-125b-5p;hsa-miR-127-5p;hsa-miR-1271-5p;hsa-miR-149-5p;hsa-miR-183-5p;hsa-miR-205-5p;hsa-miR-224-3p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-34c-3p;hsa-miR-708-5p;hsa-miR-944 15 MAP3K13 Sponge network -0.725 0.08874 0.158 0.68798 0.366
26

EMX2OS

hsa-miR-107;hsa-miR-15a-5p;hsa-miR-15b-3p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-192-5p;hsa-miR-19b-1-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-21-3p;hsa-miR-215-5p;hsa-miR-222-3p;hsa-miR-29a-5p;hsa-miR-335-3p;hsa-miR-424-5p;hsa-miR-503-5p;hsa-miR-577;hsa-miR-589-3p;hsa-miR-92a-3p;hsa-miR-93-3p 22 FGF2 Sponge network -1.088 0.10042 -1.879 0.00013 0.362
27

MEG3

hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-200c-5p;hsa-miR-31-5p;hsa-miR-339-5p;hsa-miR-429;hsa-miR-550a-3p;hsa-miR-7-1-3p;hsa-miR-93-3p;hsa-miR-96-5p 10 CACNB2 Sponge network -1.645 0.00049 -2.086 1.0E-5 0.357
28

RFPL1S

hsa-miR-148b-5p;hsa-miR-17-3p;hsa-miR-18a-3p;hsa-miR-29a-5p;hsa-miR-320b;hsa-miR-335-5p;hsa-miR-34a-5p;hsa-miR-362-3p;hsa-miR-429;hsa-miR-7-1-3p 10 MAPT Sponge network -0.223 0.70704 -2.812 0 0.357
29

EMX2OS

hsa-miR-107;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-32-3p;hsa-miR-335-3p;hsa-miR-362-3p;hsa-miR-501-3p;hsa-miR-502-3p;hsa-miR-505-3p;hsa-miR-577 12 AKT3 Sponge network -1.088 0.10042 -0.749 0.06936 0.354
30

CASC2

hsa-let-7b-5p;hsa-miR-152-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-342-3p 10 NLK Sponge network -0.561 0.05962 0.087 0.60941 0.352
31

CASC2

hsa-miR-125b-5p;hsa-miR-127-5p;hsa-miR-1271-5p;hsa-miR-149-5p;hsa-miR-183-5p;hsa-miR-205-5p;hsa-miR-224-3p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-369-3p;hsa-miR-708-5p;hsa-miR-940;hsa-miR-944 16 MAP3K13 Sponge network -0.561 0.05962 0.158 0.68798 0.349
32

EMX2OS

hsa-miR-107;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-2-3p;hsa-miR-16-5p;hsa-miR-18a-3p;hsa-miR-20a-5p;hsa-miR-424-5p;hsa-miR-577;hsa-miR-7-1-3p 10 FGF7 Sponge network -1.088 0.10042 -1.56 0.00499 0.338
33

AGAP11

hsa-let-7f-1-3p;hsa-let-7g-3p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-15b-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-421;hsa-miR-424-5p;hsa-miR-590-5p 12 PPM1A Sponge network -1.728 0.00016 -0.485 0.00196 0.335
34

AGAP11

hsa-miR-16-1-3p;hsa-miR-18a-5p;hsa-miR-222-5p;hsa-miR-26b-3p;hsa-miR-29a-5p;hsa-miR-320b;hsa-miR-326;hsa-miR-532-3p;hsa-miR-590-5p;hsa-miR-629-5p 10 FGF1 Sponge network -1.728 0.00016 -0.16 0.73397 0.329
35

RFPL1S

hsa-miR-107;hsa-miR-192-5p;hsa-miR-19b-1-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-20a-3p;hsa-miR-215-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-29a-5p;hsa-miR-335-5p;hsa-miR-429 12 FGF2 Sponge network -0.223 0.70704 -1.879 0.00013 0.314
36

MEG3

hsa-miR-106b-5p;hsa-miR-107;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-33a-3p;hsa-miR-577;hsa-miR-616-5p 11 AKT3 Sponge network -1.645 0.00049 -0.749 0.06936 0.312
37

PCA3

hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-let-7g-3p;hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-149-5p;hsa-miR-16-1-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-196a-5p;hsa-miR-196b-5p;hsa-miR-20a-5p;hsa-miR-219a-5p;hsa-miR-224-5p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-301a-3p;hsa-miR-33a-5p;hsa-miR-33b-5p;hsa-miR-590-5p;hsa-miR-93-5p;hsa-miR-944;hsa-miR-96-5p 26 PDGFRA Sponge network -2.778 8.0E-5 -1.161 0.00469 0.31
38

EMX2OS

hsa-miR-107;hsa-miR-1254;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-200b-3p;hsa-miR-200c-3p;hsa-miR-33b-5p;hsa-miR-378a-5p;hsa-miR-577;hsa-miR-589-3p;hsa-miR-7-1-3p;hsa-miR-877-5p;hsa-miR-93-3p 13 CACNA1C Sponge network -1.088 0.10042 -1.469 0.0005 0.306
39

EMX2OS

hsa-miR-130b-5p;hsa-miR-135b-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-18a-3p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-200c-5p;hsa-miR-32-3p;hsa-miR-335-3p;hsa-miR-33b-5p;hsa-miR-425-5p;hsa-miR-550a-3p;hsa-miR-92a-3p 14 MEF2C Sponge network -1.088 0.10042 -0.552 0.096 0.304
40

PLAC4

hsa-let-7a-2-3p;hsa-let-7b-5p;hsa-miR-152-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-28-5p 11 NLK Sponge network -0.563 0.27163 0.087 0.60941 0.302
41

RFPL1S

hsa-miR-126-5p;hsa-miR-18a-5p;hsa-miR-222-5p;hsa-miR-26b-3p;hsa-miR-29a-5p;hsa-miR-320b;hsa-miR-330-5p;hsa-miR-429;hsa-miR-532-3p;hsa-miR-550a-5p;hsa-miR-625-5p;hsa-miR-7-5p 12 FGF1 Sponge network -0.223 0.70704 -0.16 0.73397 0.3
42

HCG18

hsa-miR-127-5p;hsa-miR-149-5p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-331-3p;hsa-miR-379-5p;hsa-miR-511-5p 10 RAPGEF2 Sponge network -0.24 0.23472 -0.748 0.00078 0.288
43

HCG18

hsa-let-7a-2-3p;hsa-let-7b-5p;hsa-miR-152-3p;hsa-miR-199a-3p;hsa-miR-199b-3p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-28-5p 11 NLK Sponge network -0.24 0.23472 0.087 0.60941 0.285
44

PCA3

hsa-miR-106b-5p;hsa-miR-130a-3p;hsa-miR-130b-3p;hsa-miR-17-5p;hsa-miR-18a-5p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-23a-3p;hsa-miR-301a-3p;hsa-miR-320b;hsa-miR-33a-3p;hsa-miR-590-3p;hsa-miR-590-5p;hsa-miR-93-5p 14 TGFBR2 Sponge network -2.778 8.0E-5 -1.331 0.00013 0.283
45

EMX2OS

hsa-miR-135b-5p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-200a-5p;hsa-miR-200b-5p;hsa-miR-20a-5p;hsa-miR-335-3p;hsa-miR-577 10 FGFR1 Sponge network -1.088 0.10042 -1.499 0.00051 0.281
46

NEAT1

hsa-miR-125b-5p;hsa-miR-127-5p;hsa-miR-1271-5p;hsa-miR-149-5p;hsa-miR-183-5p;hsa-miR-224-3p;hsa-miR-23a-3p;hsa-miR-24-3p;hsa-miR-34c-3p;hsa-miR-708-5p;hsa-miR-940 11 MAP3K13 Sponge network -0.686 0.02293 0.158 0.68798 0.281
47

MALAT1

hsa-miR-1296-5p;hsa-miR-183-5p;hsa-miR-224-3p;hsa-miR-23a-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-324-3p;hsa-miR-331-5p;hsa-miR-33b-5p;hsa-miR-452-5p;hsa-miR-744-3p 11 MEF2C Sponge network -1.099 0.0005 -0.552 0.096 0.28
48

PCA3

hsa-miR-103a-2-5p;hsa-miR-1271-5p;hsa-miR-130b-5p;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-182-5p;hsa-miR-186-5p;hsa-miR-193b-5p;hsa-miR-197-3p;hsa-miR-221-3p;hsa-miR-320b;hsa-miR-424-5p;hsa-miR-590-3p 15 DUSP3 Sponge network -2.778 8.0E-5 -0.882 0 0.279
49

EMX2OS

hsa-miR-107;hsa-miR-1254;hsa-miR-141-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-185-3p;hsa-miR-188-5p;hsa-miR-200a-3p;hsa-miR-20a-5p;hsa-miR-331-3p;hsa-miR-33b-5p;hsa-miR-424-5p;hsa-miR-505-3p;hsa-miR-7-1-3p 17 MAP3K3 Sponge network -1.088 0.10042 -0.635 0.00017 0.279
50

PCA3

hsa-miR-183-5p;hsa-miR-193b-3p;hsa-miR-193b-5p;hsa-miR-200c-3p;hsa-miR-22-5p;hsa-miR-224-5p;hsa-miR-2355-3p;hsa-miR-369-3p;hsa-miR-590-3p;hsa-miR-93-3p;hsa-miR-944 11 PRKCA Sponge network -2.778 8.0E-5 -0.525 0.15685 0.278
51

MALAT1

hsa-miR-1271-5p;hsa-miR-149-5p;hsa-miR-183-5p;hsa-miR-224-3p;hsa-miR-23a-3p;hsa-miR-23b-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-27b-3p;hsa-miR-34c-3p 10 MAP3K13 Sponge network -1.099 0.0005 0.158 0.68798 0.276
52

PCA3

hsa-miR-106b-5p;hsa-miR-127-5p;hsa-miR-149-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-23a-3p;hsa-miR-24-3p;hsa-miR-27a-3p;hsa-miR-331-3p;hsa-miR-369-3p;hsa-miR-940;hsa-miR-944 12 RAPGEF2 Sponge network -2.778 8.0E-5 -0.748 0.00078 0.274
53 HAR1A hsa-miR-103a-2-5p;hsa-miR-130b-5p;hsa-miR-135b-5p;hsa-miR-182-5p;hsa-miR-183-5p;hsa-miR-18a-3p;hsa-miR-18a-5p;hsa-miR-224-3p;hsa-miR-27a-3p;hsa-miR-324-3p;hsa-miR-744-3p;hsa-miR-940 12 MEF2C Sponge network -0.801 0.17598 -0.552 0.096 0.272
54

EMX2OS

hsa-let-7d-5p;hsa-miR-107;hsa-miR-15b-3p;hsa-miR-15b-5p;hsa-miR-183-5p;hsa-miR-196a-5p;hsa-miR-196b-5p;hsa-miR-20a-3p;hsa-miR-335-3p;hsa-miR-550a-3p;hsa-miR-92a-3p 11 CACNB4 Sponge network -1.088 0.10042 -2.124 0.00021 0.266
55

AGAP11

hsa-miR-106b-5p;hsa-miR-107;hsa-miR-128-3p;hsa-miR-1292-5p;hsa-miR-130b-3p;hsa-miR-148b-3p;hsa-miR-17-5p;hsa-miR-18a-5p;hsa-miR-19a-3p;hsa-miR-19b-3p;hsa-miR-20a-3p;hsa-miR-20a-5p;hsa-miR-335-3p;hsa-miR-942-5p 14 RPS6KA5 Sponge network -1.728 0.00016 -1.153 4.0E-5 0.264
56

AGAP11

hsa-let-7d-5p;hsa-miR-107;hsa-miR-15b-3p;hsa-miR-15b-5p;hsa-miR-196a-5p;hsa-miR-196b-5p;hsa-miR-20a-3p;hsa-miR-320b;hsa-miR-335-3p;hsa-miR-421;hsa-miR-550a-3p 11 CACNB4 Sponge network -1.728 0.00016 -2.124 0.00021 0.26
57

EMX2OS

hsa-let-7g-3p;hsa-miR-130b-3p;hsa-miR-141-3p;hsa-miR-17-5p;hsa-miR-182-5p;hsa-miR-196a-5p;hsa-miR-196b-5p;hsa-miR-20a-5p;hsa-miR-335-3p;hsa-miR-33b-5p 10 PDGFRA Sponge network -1.088 0.10042 -1.161 0.00469 0.259
58

PCA3

hsa-let-7f-1-3p;hsa-let-7g-3p;hsa-miR-106b-5p;hsa-miR-107;hsa-miR-15b-5p;hsa-miR-16-1-3p;hsa-miR-16-5p;hsa-miR-186-5p;hsa-miR-32-3p;hsa-miR-320b;hsa-miR-3613-5p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-590-5p 14 PPM1A Sponge network -2.778 8.0E-5 -0.485 0.00196 0.259
59

PCA3

hsa-miR-130b-3p;hsa-miR-15a-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-320b;hsa-miR-330-3p;hsa-miR-335-5p;hsa-miR-424-5p;hsa-miR-590-3p;hsa-miR-590-5p 10 SOS2 Sponge network -2.778 8.0E-5 -0.553 0.00084 0.258
60

PCA3

hsa-let-7f-1-3p;hsa-miR-141-3p;hsa-miR-16-2-3p;hsa-miR-17-5p;hsa-miR-183-5p;hsa-miR-18a-5p;hsa-miR-200c-3p;hsa-miR-330-3p;hsa-miR-590-5p;hsa-miR-93-5p;hsa-miR-96-5p 11 PRKACB Sponge network -2.778 8.0E-5 -2.003 0 0.257

Quest ID: e645a90e1332c441149800d0f4657e3f