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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-let-7a-3p ABCA1 1.42 0 -0.71 0.00276 mirMAP; miRNATAP -0.28 0 NA
2 hsa-miR-183-5p ABCA1 4.2 0 -0.71 0.00276 MirTarget; miRNATAP -0.15 0 26935154 MiR 183 functions as an oncogene by targeting ABCA1 in colon cancer; We found that miR-183 targets the 3'UTR of ABCA1 mRNA; Subsequent experiments confirmed that miR-183 degraded ABCA1 mRNA in the colon cancer cells; Thus we conclude that miR-183 promotes proliferation and inhibits apoptosis by degrading ABCA1 in colon cancer
3 hsa-let-7f-1-3p ABCA5 1.55 0 -0.2 0.46525 mirMAP -0.15 0.0069 NA
4 hsa-miR-183-5p ABCA8 4.2 0 -5.33 0 MirTarget -0.45 0 NA
5 hsa-let-7a-3p ABCC4 1.42 0 -1.54 1.0E-5 mirMAP -0.19 0.01906 NA
6 hsa-let-7a-3p ABCC9 1.42 0 -2.76 0 mirMAP -0.65 0 NA
7 hsa-let-7f-1-3p ABCC9 1.55 0 -2.76 0 mirMAP -0.35 4.0E-5 NA
8 hsa-let-7a-3p ABCD2 1.42 0 -3.08 0 mirMAP -0.67 0 NA
9 hsa-let-7a-3p ABCD3 1.42 0 0.14 0.52609 MirTarget -0.12 0.02959 NA
10 hsa-let-7a-3p ABI3BP 1.42 0 -4.28 0 miRNATAP -0.98 0 NA
11 hsa-miR-181b-5p ABI3BP 2.49 0 -4.28 0 miRNATAP -0.74 0 NA
12 hsa-miR-15a-5p ABL2 2.35 0 -0.32 0.04554 MirTarget; miRNATAP -0.16 0 NA
13 hsa-let-7a-3p ABLIM1 1.42 0 -1.72 0 mirMAP -0.15 0.02468 NA
14 hsa-let-7f-1-3p ABLIM1 1.55 0 -1.72 0 mirMAP -0.12 0.03467 NA
15 hsa-miR-181b-5p ACSL1 2.49 0 -0 0.993 MirTarget -0.12 0.00517 NA
16 hsa-miR-181b-5p ACSS3 2.49 0 -2.48 1.0E-5 MirTarget -0.25 0.01051 NA
17 hsa-miR-181d-5p ACSS3 1.52 0 -2.48 1.0E-5 MirTarget -0.2 0.03508 NA
18 hsa-miR-194-5p ACTR3 1.9 0 -0.05 0.71644 mirMAP -0.11 0 NA
19 hsa-miR-224-5p ADAM22 2.94 0 -1.12 0.02589 MirTarget -0.15 0.00075 NA
20 hsa-miR-181b-5p ADAMTS1 2.49 0 -3.81 0 miRNATAP -0.53 0 NA
21 hsa-miR-15a-5p ADAMTS18 2.35 0 -0.74 0.14599 miRNATAP -0.48 0 NA
22 hsa-miR-181b-5p ADAMTS18 2.49 0 -0.74 0.14599 miRNATAP -0.17 0.04646 NA
23 hsa-miR-224-5p ADAMTS2 2.94 0 -0.77 0.15763 mirMAP -0.21 1.0E-5 NA
24 hsa-miR-15a-5p ADAMTS3 2.35 0 -1.18 0.00448 miRNATAP -0.53 0 NA
25 hsa-let-7a-3p ADAMTS5 1.42 0 -2.16 0 mirMAP -0.34 1.0E-5 NA
26 hsa-let-7f-1-3p ADAMTS5 1.55 0 -2.16 0 mirMAP -0.27 9.0E-5 NA
27 hsa-miR-15a-5p ADAMTS5 2.35 0 -2.16 0 miRNATAP -0.43 0 NA
28 hsa-miR-181b-5p ADAMTS5 2.49 0 -2.16 0 mirMAP; miRNATAP -0.25 1.0E-5 NA
29 hsa-miR-194-5p ADAMTS5 1.9 0 -2.16 0 mirMAP -0.26 0 NA
30 hsa-miR-181b-5p ADAMTS6 2.49 0 -0.88 0.01914 miRNATAP -0.13 0.03705 NA
31 hsa-let-7f-1-3p ADAMTS9 1.55 0 -1.79 0 mirMAP -0.32 0 NA
32 hsa-miR-181b-5p ADAMTSL1 2.49 0 -2.52 0 miRNATAP -0.35 1.0E-5 NA
33 hsa-let-7a-3p ADAMTSL3 1.42 0 -5.11 0 MirTarget -1.04 0 NA
34 hsa-let-7f-1-3p ADAMTSL3 1.55 0 -5.11 0 MirTarget -0.47 9.0E-5 NA
35 hsa-miR-15a-5p ADAMTSL3 2.35 0 -5.11 0 MirTarget -1.2 0 NA
36 hsa-miR-181b-5p ADARB1 2.49 0 -1.93 0 MirTarget; miRNATAP -0.36 0 NA
37 hsa-miR-181d-5p ADARB1 1.52 0 -1.93 0 MirTarget -0.26 0 NA
38 hsa-miR-224-5p ADARB1 2.94 0 -1.93 0 mirMAP -0.2 0 NA
39 hsa-miR-15a-5p ADCY5 2.35 0 -5.17 0 MirTarget; miRNATAP -1.03 0 NA
40 hsa-miR-181b-5p ADCY9 2.49 0 -1.5 0 miRNATAP -0.24 0 24269684 miR 181b promotes cell proliferation and reduces apoptosis by repressing the expression of adenylyl cyclase 9 AC9 in cervical cancer cells; Phenotypic experiments indicated that miR-181b and AC9 exerted opposite effects on cell proliferation and apoptosis
41 hsa-let-7a-3p ADCYAP1 1.42 0 -3.51 0 miRNATAP -0.66 0 NA
42 hsa-miR-224-5p ADCYAP1 2.94 0 -3.51 0 mirMAP -0.27 0 NA
43 hsa-let-7a-3p ADD3 1.42 0 -0.66 0.00185 mirMAP; miRNATAP -0.14 0.00449 NA
44 hsa-let-7f-1-3p ADH4 1.55 0 -0.4 0.49752 MirTarget -0.3 0.01359 NA
45 hsa-let-7f-1-3p ADH5 1.55 0 -0.62 0.00021 MirTarget -0.11 0.00177 NA
46 hsa-miR-181d-5p ADM 1.52 0 -0.13 0.70322 MirTarget -0.25 2.0E-5 NA
47 hsa-miR-15a-5p ADRB2 2.35 0 -1.96 1.0E-5 MirTarget -0.26 0.00282 NA
48 hsa-miR-181b-5p AFF1 2.49 0 -0.53 0.00163 mirMAP; miRNATAP -0.11 0.00021 NA
49 hsa-let-7a-3p AFF2 1.42 0 -1.73 0.00201 mirMAP -0.29 0.02983 NA
50 hsa-let-7a-3p AFF3 1.42 0 -5 0 MirTarget -1.07 0 NA
51 hsa-let-7f-1-3p AFF3 1.55 0 -5 0 MirTarget -0.84 0 NA
52 hsa-miR-224-5p AFF3 2.94 0 -5 0 MirTarget -0.33 0 NA
53 hsa-miR-15a-5p AFF4 2.35 0 -0.82 0 MirTarget; miRNATAP -0.13 2.0E-5 NA
54 hsa-miR-181b-5p AFF4 2.49 0 -0.82 0 mirMAP; miRNATAP -0.12 0 NA
55 hsa-miR-181d-5p AGFG1 1.52 0 -0.17 0.30925 MirTarget -0.16 0 NA
56 hsa-miR-181b-5p AGFG2 2.49 0 -0.51 0.00539 mirMAP -0.11 0.00068 NA
57 hsa-miR-15a-5p AGPAT4 2.35 0 -0.79 0.01174 mirMAP -0.18 0.0035 NA
58 hsa-miR-224-5p AIF1L 2.94 0 -1.46 0.00033 mirMAP -0.13 0.00032 NA
59 hsa-miR-183-5p AJAP1 4.2 0 -1.65 0.0004 MirTarget -0.11 0.04924 NA
60 hsa-let-7a-3p AKAP11 1.42 0 -0.8 0 mirMAP -0.16 4.0E-5 NA
61 hsa-let-7f-1-3p AKAP11 1.55 0 -0.8 0 mirMAP -0.1 0.00245 NA
62 hsa-miR-15a-5p AKAP11 2.35 0 -0.8 0 MirTarget; miRNATAP -0.13 4.0E-5 NA
63 hsa-let-7a-3p AKAP12 1.42 0 -2.95 0 miRNATAP -0.59 0 NA
64 hsa-miR-183-5p AKAP12 4.2 0 -2.95 0 miRNAWalker2 validate; miRTarBase -0.33 0 NA
65 hsa-miR-15a-5p AKIRIN1 2.35 0 -0.65 1.0E-5 miRNATAP -0.11 0.00016 NA
66 hsa-miR-15a-5p AKT3 2.35 0 -1.94 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.65 0 NA
67 hsa-miR-181b-5p AKT3 2.49 0 -1.94 0 miRNATAP -0.27 1.0E-5 NA
68 hsa-let-7a-3p AKTIP 1.42 0 -0.35 0.01135 MirTarget -0.14 3.0E-5 NA
69 hsa-let-7f-1-3p AKTIP 1.55 0 -0.35 0.01135 MirTarget -0.12 2.0E-5 NA
70 hsa-let-7a-3p ALDH1L2 1.42 0 -1.12 0.02448 MirTarget -0.24 0.04301 NA
71 hsa-miR-194-5p ALDH1L2 1.9 0 -1.12 0.02448 mirMAP -0.62 0 NA
72 hsa-miR-224-5p ALDH1L2 2.94 0 -1.12 0.02448 mirMAP -0.15 0.00057 NA
73 hsa-let-7f-1-3p AMIGO2 1.55 0 0.86 0.01664 MirTarget; mirMAP -0.16 0.03642 NA
74 hsa-let-7a-3p AMN1 1.42 0 -0.48 0.00493 mirMAP -0.12 0.00228 NA
75 hsa-let-7f-1-3p AMN1 1.55 0 -0.48 0.00493 mirMAP -0.19 0 NA
76 hsa-let-7a-3p AMOT 1.42 0 -1.51 0.00385 mirMAP -0.61 0 NA
77 hsa-let-7f-1-3p AMOT 1.55 0 -1.51 0.00385 mirMAP -0.22 0.03893 NA
78 hsa-let-7a-3p AMOTL1 1.42 0 -1.62 0 mirMAP -0.29 3.0E-5 NA
79 hsa-miR-15a-5p AMOTL1 2.35 0 -1.62 0 MirTarget; miRNATAP -0.52 0 NA
80 hsa-let-7a-3p AMOTL2 1.42 0 -1.01 0.00015 miRNATAP -0.19 0.00261 NA
81 hsa-miR-194-5p ANGPTL1 1.9 0 -4.51 0 MirTarget -0.72 0 NA
82 hsa-miR-15a-5p ANK2 2.35 0 -4.32 0 MirTarget; miRNATAP -1.15 0 NA
83 hsa-miR-181b-5p ANKRD12 2.49 0 -0.64 0.00012 mirMAP -0.12 1.0E-5 NA
84 hsa-miR-15a-5p ANKRD29 2.35 0 -3.47 0 MirTarget -1.03 0 NA
85 hsa-let-7f-1-3p ANKRD50 1.55 0 -0.88 0.00174 MirTarget; mirMAP -0.21 0.0002 NA
86 hsa-miR-15a-5p ANKS1A 2.35 0 -0.38 0.09203 MirTarget -0.1 0.02061 NA
87 hsa-let-7a-3p ANKS1B 1.42 0 -3.65 0 miRNATAP -0.78 0 NA
88 hsa-let-7a-3p ANO5 1.42 0 -3.19 0 mirMAP -0.88 0 NA
89 hsa-let-7f-1-3p ANO5 1.55 0 -3.19 0 mirMAP -0.96 0 NA
90 hsa-let-7a-3p ANTXR1 1.42 0 -0.71 0.0159 mirMAP; miRNATAP -0.29 5.0E-5 NA
91 hsa-miR-181b-5p ANTXR2 2.49 0 -2.31 0 mirMAP -0.41 0 NA
92 hsa-miR-181b-5p ANXA11 2.49 0 -0.43 0.01849 MirTarget; mirMAP -0.13 1.0E-5 NA
93 hsa-miR-224-5p APBA2 2.94 0 0.53 0.28746 MirTarget -0.13 0.00322 NA
94 hsa-miR-15a-5p APLNR 2.35 0 -0.23 0.52454 MirTarget -0.27 0.00014 NA
95 hsa-miR-15a-5p APP 2.35 0 -0.4 0.04288 miRNAWalker2 validate; miRNATAP -0.22 0 NA
96 hsa-miR-15a-5p AR 2.35 0 -3.3 0 mirMAP; miRNATAP -0.52 8.0E-5 NA
97 hsa-miR-181b-5p AR 2.49 0 -3.3 0 miRNATAP -0.48 3.0E-5 NA
98 hsa-let-7a-3p ARHGAP20 1.42 0 -3.52 0 MirTarget; miRNATAP -0.72 0 NA
99 hsa-let-7f-1-3p ARHGAP20 1.55 0 -3.52 0 MirTarget -0.41 1.0E-5 NA
100 hsa-miR-15a-5p ARHGAP20 2.35 0 -3.52 0 MirTarget; miRNATAP -0.92 0 NA
101 hsa-miR-194-5p ARHGAP21 1.9 0 -0.23 0.20424 MirTarget; miRNATAP -0.13 0 NA
102 hsa-miR-194-5p ARHGAP24 1.9 0 -2.02 0 miRNATAP -0.46 0 NA
103 hsa-let-7a-3p ARHGAP28 1.42 0 -1.54 0.00053 mirMAP -0.4 0.00021 NA
104 hsa-let-7a-3p ARHGAP29 1.42 0 -0.34 0.31665 mirMAP -0.24 0.00278 NA
105 hsa-miR-15a-5p ARHGAP5 2.35 0 -0.63 0.00047 MirTarget; miRNATAP -0.14 0.00012 NA
106 hsa-miR-181b-5p ARHGAP5 2.49 0 -0.63 0.00047 mirMAP -0.13 3.0E-5 NA
107 hsa-miR-183-5p ARHGAP6 4.2 0 -3.25 0 MirTarget; miRNATAP -0.25 0 NA
108 hsa-miR-15a-5p ARHGEF12 2.35 0 -0.64 4.0E-5 MirTarget -0.12 8.0E-5 NA
109 hsa-let-7a-3p ARHGEF3 1.42 0 -0.76 0 MirTarget -0.16 4.0E-5 NA
110 hsa-miR-181b-5p ARHGEF3 2.49 0 -0.76 0 MirTarget -0.12 3.0E-5 NA
111 hsa-miR-15a-5p ARHGEF9 2.35 0 -1.21 0 miRNATAP -0.19 0 NA
112 hsa-let-7a-3p ARID4A 1.42 0 -0.76 0 MirTarget; miRNATAP -0.12 0.00103 NA
113 hsa-let-7f-1-3p ARID4A 1.55 0 -0.76 0 MirTarget -0.16 0 NA
114 hsa-let-7a-3p ARID5B 1.42 0 -1.57 0 miRNATAP -0.33 0 NA
115 hsa-miR-15a-5p ARL2 2.35 0 -0.16 0.28726 MirTarget; miRNATAP -0.13 2.0E-5 NA
116 hsa-miR-181d-5p ARL5A 1.52 0 -0.5 0.00021 MirTarget -0.11 0 NA
117 hsa-miR-15a-5p ARNT2 2.35 0 -1.45 0.00019 mirMAP -0.35 0 NA
118 hsa-miR-181b-5p ARNT2 2.49 0 -1.45 0.00019 miRNATAP -0.23 0.00069 NA
119 hsa-miR-181b-5p ARRDC3 2.49 0 -0.71 0.00062 MirTarget; mirMAP; miRNATAP -0.13 0.00027 NA
120 hsa-miR-181d-5p ARRDC3 1.52 0 -0.71 0.00062 MirTarget -0.12 0.00063 NA
121 hsa-miR-181b-5p ARRDC4 2.49 0 -1.43 0 miRNATAP -0.24 0 NA
122 hsa-let-7a-3p ARSB 1.42 0 -0.58 0.00052 mirMAP -0.14 0.00029 NA
123 hsa-miR-181b-5p ARSJ 2.49 0 -1.58 0.00066 MirTarget; miRNATAP -0.21 0.0097 NA
124 hsa-miR-181d-5p ARSJ 1.52 0 -1.58 0.00066 MirTarget -0.52 0 NA
125 hsa-let-7a-3p ART4 1.42 0 -1.65 0.00419 mirMAP -0.63 1.0E-5 NA
126 hsa-let-7f-1-3p ART4 1.55 0 -1.65 0.00419 mirMAP -0.24 0.04427 NA
127 hsa-let-7a-3p ASAH1 1.42 0 -0.59 0.00556 MirTarget -0.19 0.00013 NA
128 hsa-let-7f-1-3p ASAH1 1.55 0 -0.59 0.00556 MirTarget -0.16 0.00037 NA
129 hsa-miR-194-5p ASAP1 1.9 0 0.06 0.77944 MirTarget; miRNATAP -0.11 0.00108 NA
130 hsa-miR-15a-5p ASB1 2.35 0 -0.87 0 MirTarget; miRNATAP -0.12 6.0E-5 NA
131 hsa-miR-183-5p ASB1 4.2 0 -0.87 0 mirMAP -0.14 0 NA
132 hsa-miR-15a-5p ASH1L 2.35 0 -0.67 0.00016 MirTarget; miRNATAP -0.19 0 NA
133 hsa-miR-181b-5p ASPA 2.49 0 -4.76 0 mirMAP -0.33 0.00104 NA
134 hsa-miR-15a-5p ASTN1 2.35 0 -2.34 2.0E-5 MirTarget -0.29 0.00731 NA
135 hsa-let-7a-3p ASTN2 1.42 0 -0.88 0.05369 mirMAP -0.38 0.00047 NA
136 hsa-let-7f-1-3p ASTN2 1.55 0 -0.88 0.05369 mirMAP -0.22 0.02244 NA
137 hsa-miR-15a-5p ASXL2 2.35 0 -0.51 0.09339 miRNAWalker2 validate -0.26 1.0E-5 NA
138 hsa-miR-181b-5p ASXL2 2.49 0 -0.51 0.09339 mirMAP -0.17 0.00114 NA
139 hsa-let-7a-3p ATE1 1.42 0 -1.09 3.0E-5 mirMAP -0.16 0.01164 NA
140 hsa-miR-181b-5p ATE1 2.49 0 -1.09 3.0E-5 mirMAP -0.24 0 NA
141 hsa-miR-194-5p ATE1 1.9 0 -1.09 3.0E-5 MirTarget -0.1 0.0104 NA
142 hsa-miR-15a-5p ATF2 2.35 0 -0.36 0.09137 miRNAWalker2 validate -0.17 4.0E-5 NA
143 hsa-miR-181b-5p ATF2 2.49 0 -0.36 0.09137 mirMAP; miRNATAP -0.1 0.00428 NA
144 hsa-miR-194-5p ATF2 1.9 0 -0.36 0.09137 miRNATAP -0.11 0.00127 NA
145 hsa-miR-15a-5p ATF6 2.35 0 0.09 0.54553 MirTarget -0.11 0.0004 NA
146 hsa-miR-194-5p ATL3 1.9 0 -0.19 0.4343 MirTarget -0.21 0 NA
147 hsa-miR-181b-5p ATM 2.49 0 -0.69 1.0E-5 MirTarget -0.11 8.0E-5 21102523; 23656790 Ataxia telangiectasia mutated ATM a target gene of miR-181 exhibited reduced expression in mammospheres and upon TGF-β treatment;We report that miR-181a and miR-181b were overexpressed in more aggressive breast cancers and their expression correlates inversely with ATM levels
148 hsa-miR-183-5p ATP2B4 4.2 0 -1.72 0 MirTarget; miRNATAP -0.26 0 NA
149 hsa-miR-181b-5p ATP8A1 2.49 0 -1.48 8.0E-5 MirTarget; miRNATAP -0.33 0 NA
150 hsa-miR-181d-5p ATP8A1 1.52 0 -1.48 8.0E-5 MirTarget -0.16 0.01392 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 243 1672 5.781e-33 2.69e-29
2 NEUROGENESIS 213 1402 1.92e-31 4.466e-28
3 CARDIOVASCULAR SYSTEM DEVELOPMENT 144 788 2.11e-29 2.455e-26
4 CIRCULATORY SYSTEM DEVELOPMENT 144 788 2.11e-29 2.455e-26
5 TISSUE DEVELOPMENT 217 1518 2.947e-28 2.743e-25
6 REGULATION OF CELL DIFFERENTIATION 212 1492 3.172e-27 2.46e-24
7 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 174 1142 1.031e-25 6.854e-23
8 CELL DEVELOPMENT 201 1426 2.518e-25 1.464e-22
9 REGULATION OF CELL DEVELOPMENT 141 836 3.566e-25 1.843e-22
10 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 158 1021 4.585e-24 2.133e-21
11 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 129 750 7.345e-24 3.107e-21
12 VASCULATURE DEVELOPMENT 96 469 1.727e-23 6.697e-21
13 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 193 1395 2.567e-23 9.188e-21
14 ORGAN MORPHOGENESIS 137 841 5.238e-23 1.741e-20
15 HEART DEVELOPMENT 93 466 5.7e-22 1.768e-19
16 REGULATION OF NEURON DIFFERENTIATION 102 554 2.998e-21 8.72e-19
17 BLOOD VESSEL MORPHOGENESIS 79 364 3.786e-21 9.901e-19
18 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 176 1275 3.83e-21 9.901e-19
19 INTRACELLULAR SIGNAL TRANSDUCTION 203 1572 7.101e-21 1.739e-18
20 REGULATION OF PHOSPHORUS METABOLIC PROCESS 207 1618 8.337e-21 1.94e-18
21 BIOLOGICAL ADHESION 151 1032 1.395e-20 3.091e-18
22 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 142 957 6.101e-20 1.234e-17
23 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 208 1656 5.921e-20 1.234e-17
24 RESPONSE TO ENDOGENOUS STIMULUS 189 1450 7.174e-20 1.391e-17
25 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 146 1008 1.678e-19 3.07e-17
26 REGULATION OF CELLULAR COMPONENT MOVEMENT 122 771 1.715e-19 3.07e-17
27 NEURON DIFFERENTIATION 131 874 8.115e-19 1.398e-16
28 LOCOMOTION 154 1114 1.366e-18 2.269e-16
29 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 214 1784 3.633e-18 5.829e-16
30 POSITIVE REGULATION OF CELL DIFFERENTIATION 124 823 4.925e-18 7.639e-16
31 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 110 689 6.02e-18 9.036e-16
32 REGULATION OF CELL PROLIFERATION 187 1496 1.041e-17 1.514e-15
33 REGULATION OF PROTEIN MODIFICATION PROCESS 206 1710 1.096e-17 1.545e-15
34 PROTEIN PHOSPHORYLATION 134 944 3.314e-17 4.535e-15
35 EPITHELIUM DEVELOPMENT 134 945 3.621e-17 4.814e-15
36 MUSCLE STRUCTURE DEVELOPMENT 79 432 1.594e-16 2.061e-14
37 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 141 1036 1.735e-16 2.125e-14
38 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 141 1036 1.735e-16 2.125e-14
39 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 214 1848 1.968e-16 2.347e-14
40 TISSUE MORPHOGENESIS 90 533 2.145e-16 2.435e-14
41 REGULATION OF NEURON PROJECTION DEVELOPMENT 76 408 2.125e-16 2.435e-14
42 POSITIVE REGULATION OF CELL COMMUNICATION 186 1532 2.572e-16 2.85e-14
43 CENTRAL NERVOUS SYSTEM DEVELOPMENT 124 872 4.865e-16 5.264e-14
44 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 87 513 5.297e-16 5.601e-14
45 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 208 1805 9.633e-16 9.961e-14
46 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 78 437 1.012e-15 1.024e-13
47 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 135 1004 2.166e-15 2.145e-13
48 HEAD DEVELOPMENT 106 709 2.585e-15 2.506e-13
49 POSITIVE REGULATION OF CELL DEVELOPMENT 81 472 2.819e-15 2.677e-13
50 CELLULAR COMPONENT MORPHOGENESIS 124 900 5.433e-15 5.056e-13
51 TUBE DEVELOPMENT 89 552 5.589e-15 5.099e-13
52 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 114 799 6.379e-15 5.662e-13
53 POSITIVE REGULATION OF MOLECULAR FUNCTION 204 1791 6.449e-15 5.662e-13
54 CELL MOTILITY 117 835 1.016e-14 8.598e-13
55 LOCALIZATION OF CELL 117 835 1.016e-14 8.598e-13
56 REGULATION OF CELL PROJECTION ORGANIZATION 89 558 1.078e-14 8.961e-13
57 REGULATION OF CELL MORPHOGENESIS 88 552 1.577e-14 1.287e-12
58 SKELETAL SYSTEM DEVELOPMENT 77 455 3.003e-14 2.409e-12
59 TUBE MORPHOGENESIS 62 323 3.158e-14 2.49e-12
60 RESPONSE TO OXYGEN CONTAINING COMPOUND 166 1381 3.236e-14 2.509e-12
61 EMBRYO DEVELOPMENT 121 894 4.352e-14 3.266e-12
62 HEART MORPHOGENESIS 48 212 4.325e-14 3.266e-12
63 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 112 801 4.546e-14 3.358e-12
64 NEURON PROJECTION DEVELOPMENT 86 545 5.757e-14 4.185e-12
65 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 216 1977 7.236e-14 5.18e-12
66 EMBRYONIC MORPHOGENESIS 85 539 8.403e-14 5.924e-12
67 NEURON DEVELOPMENT 100 687 9.225e-14 6.406e-12
68 POSITIVE REGULATION OF NEURON DIFFERENTIATION 59 306 1.086e-13 7.43e-12
69 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 128 983 1.363e-13 9.191e-12
70 MUSCLE TISSUE DEVELOPMENT 55 275 1.558e-13 1.036e-11
71 REGULATION OF SYSTEM PROCESS 81 507 1.613e-13 1.057e-11
72 POSITIVE REGULATION OF GENE EXPRESSION 194 1733 1.804e-13 1.166e-11
73 POSITIVE REGULATION OF CELL PROLIFERATION 111 814 3.211e-13 2.047e-11
74 REGULATION OF GTPASE ACTIVITY 97 673 4.045e-13 2.544e-11
75 BEHAVIOR 81 516 4.227e-13 2.622e-11
76 POSITIVE REGULATION OF RESPONSE TO STIMULUS 209 1929 4.612e-13 2.824e-11
77 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 79 498 4.746e-13 2.868e-11
78 MUSCLE ORGAN DEVELOPMENT 54 277 7.632e-13 4.495e-11
79 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 61 337 7.588e-13 4.495e-11
80 PHOSPHORYLATION 148 1228 7.75e-13 4.508e-11
81 MORPHOGENESIS OF AN EPITHELIUM 68 400 7.949e-13 4.566e-11
82 MESENCHYME DEVELOPMENT 43 190 9.257e-13 5.253e-11
83 REGULATION OF CELL DEATH 169 1472 1.019e-12 5.71e-11
84 SINGLE ORGANISM BEHAVIOR 66 384 1.036e-12 5.737e-11
85 NEGATIVE REGULATION OF PHOSPHORYLATION 70 422 1.221e-12 6.683e-11
86 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 139 1135 1.269e-12 6.868e-11
87 REGULATION OF DEVELOPMENTAL GROWTH 55 289 1.294e-12 6.919e-11
88 DEVELOPMENTAL GROWTH 60 333 1.436e-12 7.595e-11
89 REGULATION OF MAPK CASCADE 94 660 1.91e-12 9.987e-11
90 GROWTH 68 410 2.593e-12 1.34e-10
91 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 47 229 3.5e-12 1.79e-10
92 NEGATIVE REGULATION OF CELL DIFFERENTIATION 88 609 4.522e-12 2.287e-10
93 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 81 541 5.281e-12 2.614e-10
94 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 81 541 5.281e-12 2.614e-10
95 ANGIOGENESIS 54 293 7.681e-12 3.762e-10
96 ACTIN FILAMENT BASED PROCESS 71 450 9.61e-12 4.658e-10
97 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 167 1492 1.153e-11 5.529e-10
98 CARDIAC CHAMBER DEVELOPMENT 35 144 1.413e-11 6.71e-10
99 NEGATIVE REGULATION OF CELL PROLIFERATION 90 643 1.511e-11 7.102e-10
100 RESPONSE TO GROWTH FACTOR 73 475 1.751e-11 8.147e-10
101 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 99 740 2.016e-11 9.29e-10
102 RESPONSE TO HORMONE 113 893 2.543e-11 1.16e-09
103 FOREBRAIN DEVELOPMENT 60 357 2.916e-11 1.317e-09
104 REGULATION OF HYDROLASE ACTIVITY 151 1327 3.773e-11 1.688e-09
105 NEGATIVE REGULATION OF CELL COMMUNICATION 139 1192 4.497e-11 1.993e-09
106 POSITIVE REGULATION OF CATALYTIC ACTIVITY 167 1518 4.602e-11 2.02e-09
107 POSITIVE REGULATION OF LOCOMOTION 66 420 6.245e-11 2.716e-09
108 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 153 1360 6.482e-11 2.793e-09
109 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 110 876 7.588e-11 3.239e-09
110 REGULATION OF TRANSPORT 190 1804 7.698e-11 3.256e-09
111 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 33 138 8.591e-11 3.601e-09
112 CELLULAR RESPONSE TO HORMONE STIMULUS 79 552 9.337e-11 3.879e-09
113 CELL PROJECTION ORGANIZATION 112 902 1.004e-10 4.132e-09
114 SENSORY ORGAN DEVELOPMENT 73 493 1.022e-10 4.17e-09
115 CONNECTIVE TISSUE DEVELOPMENT 40 194 1.222e-10 4.946e-09
116 CELL CELL ADHESION 84 608 1.433e-10 5.747e-09
117 REGULATION OF CELL ADHESION 86 629 1.471e-10 5.848e-09
118 UROGENITAL SYSTEM DEVELOPMENT 52 299 1.72e-10 6.781e-09
119 NEURON PROJECTION MORPHOGENESIS 63 402 1.914e-10 7.483e-09
120 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 44 232 2.568e-10 9.958e-09
121 MORPHOGENESIS OF A BRANCHING STRUCTURE 36 167 2.801e-10 1.077e-08
122 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 52 303 2.823e-10 1.077e-08
123 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 66 437 3.518e-10 1.331e-08
124 MUSCLE CELL DIFFERENTIATION 44 237 5.222e-10 1.96e-08
125 CARDIAC MUSCLE TISSUE DEVELOPMENT 32 140 5.694e-10 2.12e-08
126 CARDIAC CHAMBER MORPHOGENESIS 27 104 6.16e-10 2.275e-08
127 REGULATION OF KINASE ACTIVITY 98 776 6.382e-10 2.32e-08
128 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 83 616 6.381e-10 2.32e-08
129 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 77 554 6.467e-10 2.333e-08
130 REGULATION OF CELLULAR COMPONENT BIOGENESIS 97 767 7.266e-10 2.601e-08
131 MESENCHYMAL CELL DIFFERENTIATION 31 134 7.681e-10 2.728e-08
132 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 58 368 8.097e-10 2.854e-08
133 CARDIAC SEPTUM DEVELOPMENT 24 85 8.589e-10 3.005e-08
134 REGULATION OF EPITHELIAL CELL MIGRATION 35 166 9.298e-10 3.229e-08
135 CYTOSKELETON ORGANIZATION 103 838 1.043e-09 3.595e-08
136 NEGATIVE REGULATION OF CELL DEATH 106 872 1.098e-09 3.757e-08
137 POSITIVE REGULATION OF MAPK CASCADE 68 470 1.223e-09 4.153e-08
138 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 19 56 1.602e-09 5.402e-08
139 REGULATION OF TRANSFERASE ACTIVITY 112 946 1.685e-09 5.601e-08
140 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 130 1152 1.685e-09 5.601e-08
141 REGULATION OF OSSIFICATION 36 178 1.781e-09 5.878e-08
142 RESPONSE TO OXYGEN LEVELS 51 311 2.136e-09 7e-08
143 POSITIVE REGULATION OF HYDROLASE ACTIVITY 108 905 2.153e-09 7.007e-08
144 NEURON MIGRATION 27 110 2.368e-09 7.65e-08
145 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 33 156 2.555e-09 8.2e-08
146 EXTRACELLULAR STRUCTURE ORGANIZATION 50 304 2.769e-09 8.826e-08
147 REGULATION OF BLOOD CIRCULATION 49 295 2.849e-09 9.019e-08
148 REGULATION OF CELL SUBSTRATE ADHESION 35 173 2.958e-09 9.301e-08
149 COGNITION 44 251 3.366e-09 1.051e-07
150 POSITIVE REGULATION OF HEART GROWTH 13 27 4.091e-09 1.269e-07
151 TAXIS 66 464 4.317e-09 1.33e-07
152 VASCULOGENESIS 19 59 4.348e-09 1.331e-07
153 EPITHELIAL CELL DIFFERENTIATION 69 495 4.497e-09 1.368e-07
154 SKELETAL SYSTEM MORPHOGENESIS 38 201 4.631e-09 1.399e-07
155 POSITIVE REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 11 19 5.168e-09 1.551e-07
156 MUSCLE SYSTEM PROCESS 47 282 5.349e-09 1.585e-07
157 TELENCEPHALON DEVELOPMENT 41 228 5.343e-09 1.585e-07
158 NEGATIVE REGULATION OF CELL DEVELOPMENT 49 303 7.051e-09 2.077e-07
159 POSITIVE REGULATION OF ORGAN GROWTH 15 38 7.717e-09 2.258e-07
160 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 158 1517 8.325e-09 2.421e-07
161 INOSITOL LIPID MEDIATED SIGNALING 28 124 8.936e-09 2.583e-07
162 BONE DEVELOPMENT 32 156 9.804e-09 2.799e-07
163 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 46 278 9.793e-09 2.799e-07
164 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 25 103 1.175e-08 3.333e-07
165 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 44 262 1.295e-08 3.651e-07
166 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 25 104 1.45e-08 4.064e-07
167 RESPONSE TO WOUNDING 74 563 1.603e-08 4.466e-07
168 RESPONSE TO ABIOTIC STIMULUS 115 1024 2.056e-08 5.695e-07
169 REGULATION OF HEART CONTRACTION 39 221 2.148e-08 5.9e-07
170 REGULATION OF EPITHELIAL CELL PROLIFERATION 46 285 2.156e-08 5.9e-07
171 REGULATION OF MEMBRANE POTENTIAL 52 343 2.307e-08 6.278e-07
172 CELLULAR RESPONSE TO NITROGEN COMPOUND 68 505 2.372e-08 6.416e-07
173 REGULATION OF GROWTH 80 633 2.427e-08 6.529e-07
174 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 88 724 3.035e-08 8.116e-07
175 RESPONSE TO NITROGEN COMPOUND 100 859 3.095e-08 8.23e-07
176 BONE MORPHOGENESIS 21 79 3.115e-08 8.235e-07
177 CELLULAR RESPONSE TO LIPID 63 457 3.231e-08 8.493e-07
178 RESPONSE TO ORGANIC CYCLIC COMPOUND 105 917 3.264e-08 8.531e-07
179 STEM CELL DIFFERENTIATION 35 190 3.699e-08 9.615e-07
180 REGULATION OF ORGAN GROWTH 20 73 3.795e-08 9.809e-07
181 NEGATIVE REGULATION OF GENE EXPRESSION 153 1493 4.264e-08 1.096e-06
182 KIDNEY EPITHELIUM DEVELOPMENT 27 125 4.439e-08 1.129e-06
183 RESPONSE TO LIPID 102 888 4.42e-08 1.129e-06
184 POSITIVE REGULATION OF KINASE ACTIVITY 65 482 4.57e-08 1.156e-06
185 REGULATION OF MUSCLE TISSUE DEVELOPMENT 24 103 5.346e-08 1.345e-06
186 CARDIOCYTE DIFFERENTIATION 23 96 5.811e-08 1.446e-06
187 CARDIAC SEPTUM MORPHOGENESIS 16 49 5.799e-08 1.446e-06
188 REGULATION OF CELL JUNCTION ASSEMBLY 19 68 5.853e-08 1.449e-06
189 REGULATION OF AXONOGENESIS 32 168 6.25e-08 1.539e-06
190 CARDIAC VENTRICLE MORPHOGENESIS 18 62 6.802e-08 1.657e-06
191 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 18 62 6.802e-08 1.657e-06
192 APPENDAGE DEVELOPMENT 32 169 7.224e-08 1.742e-06
193 LIMB DEVELOPMENT 32 169 7.224e-08 1.742e-06
194 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 29 144 7.295e-08 1.75e-06
195 OUTFLOW TRACT MORPHOGENESIS 17 56 7.583e-08 1.809e-06
196 REGULATION OF CELL MATRIX ADHESION 22 90 7.639e-08 1.813e-06
197 EMBRYONIC ORGAN DEVELOPMENT 57 406 7.76e-08 1.833e-06
198 CIRCULATORY SYSTEM PROCESS 53 366 8.003e-08 1.881e-06
199 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 118 1087 8.692e-08 2.032e-06
200 SINGLE ORGANISM CELL ADHESION 62 459 8.797e-08 2.047e-06
201 REGULATION OF VASCULATURE DEVELOPMENT 39 233 9.383e-08 2.172e-06
202 RESPIRATORY SYSTEM DEVELOPMENT 35 197 9.439e-08 2.174e-06
203 CARDIAC VENTRICLE DEVELOPMENT 24 106 9.594e-08 2.199e-06
204 LIPID PHOSPHORYLATION 23 99 1.068e-07 2.437e-06
205 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 27 131 1.239e-07 2.813e-06
206 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 12 29 1.332e-07 2.993e-06
207 POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 12 29 1.332e-07 2.993e-06
208 IMMUNE SYSTEM DEVELOPMENT 73 582 1.357e-07 3.032e-06
209 CELL FATE COMMITMENT 38 227 1.362e-07 3.032e-06
210 REGULATION OF EXTENT OF CELL GROWTH 23 101 1.579e-07 3.499e-06
211 PATTERN SPECIFICATION PROCESS 57 418 2.109e-07 4.65e-06
212 RHYTHMIC PROCESS 45 298 2.256e-07 4.952e-06
213 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 38 232 2.425e-07 5.297e-06
214 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 18 67 2.502e-07 5.44e-06
215 REGULATION OF ION TRANSPORT 73 592 2.659e-07 5.755e-06
216 REGULATION OF HEART GROWTH 14 42 2.926e-07 6.303e-06
217 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 75 616 3.026e-07 6.488e-06
218 NEURAL CREST CELL DIFFERENTIATION 19 75 3.198e-07 6.826e-06
219 NEGATIVE REGULATION OF MOLECULAR FUNCTION 115 1079 3.321e-07 7.056e-06
220 REGULATION OF POSTSYNAPTIC MEMBRANE POTENTIAL 16 55 3.517e-07 7.372e-06
221 REGULATION OF BINDING 43 283 3.502e-07 7.372e-06
222 MESONEPHROS DEVELOPMENT 21 90 3.502e-07 7.372e-06
223 REGULATION OF ENDOTHELIAL CELL MIGRATION 24 114 4.063e-07 8.478e-06
224 CARTILAGE DEVELOPMENT 28 147 4.101e-07 8.518e-06
225 STRIATED MUSCLE CELL DIFFERENTIATION 31 173 4.14e-07 8.561e-06
226 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 33 191 4.247e-07 8.745e-06
227 CELL PART MORPHOGENESIS 76 633 4.398e-07 9.015e-06
228 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 61 470 4.559e-07 9.305e-06
229 POSITIVE REGULATION OF GROWTH 38 238 4.715e-07 9.579e-06
230 REGULATION OF BMP SIGNALING PATHWAY 19 77 4.98e-07 1.008e-05
231 REGULATION OF ADHERENS JUNCTION ORGANIZATION 15 50 5.242e-07 1.056e-05
232 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 32 184 5.437e-07 1.09e-05
233 PALATE DEVELOPMENT 20 85 5.736e-07 1.145e-05
234 CYCLIC NUCLEOTIDE METABOLIC PROCESS 16 57 6.028e-07 1.199e-05
235 POSITIVE REGULATION OF CELL DEATH 73 605 6.152e-07 1.218e-05
236 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 26 133 6.247e-07 1.232e-05
237 ACTIN FILAMENT BASED MOVEMENT 21 93 6.283e-07 1.234e-05
238 CELL CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 34 204 6.797e-07 1.329e-05
239 EAR DEVELOPMENT 33 195 6.919e-07 1.341e-05
240 REGULATION OF MUSCLE SYSTEM PROCESS 33 195 6.919e-07 1.341e-05
241 PEPTIDYL TYROSINE MODIFICATION 32 186 6.972e-07 1.346e-05
242 VENTRICULAR CARDIAC MUSCLE TISSUE DEVELOPMENT 14 45 7.643e-07 1.464e-05
243 NEURON PROJECTION GUIDANCE 34 205 7.635e-07 1.464e-05
244 REGIONALIZATION 45 311 7.693e-07 1.467e-05
245 NEGATIVE REGULATION OF LOCOMOTION 40 263 8.665e-07 1.646e-05
246 REGULATION OF HOMEOSTATIC PROCESS 58 447 8.783e-07 1.661e-05
247 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 27 144 9.078e-07 1.71e-05
248 REGULATION OF MUSCLE ORGAN DEVELOPMENT 22 103 9.432e-07 1.77e-05
249 PALLIUM DEVELOPMENT 28 153 9.562e-07 1.787e-05
250 CELL ACTIVATION 69 568 9.784e-07 1.821e-05
251 REGULATION OF TRANSPORTER ACTIVITY 33 198 9.868e-07 1.829e-05
252 PLATELET DERIVED GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 12 34 1.029e-06 1.892e-05
253 CAMP METABOLIC PROCESS 12 34 1.029e-06 1.892e-05
254 SYNAPSE ORGANIZATION 27 145 1.046e-06 1.915e-05
255 AMEBOIDAL TYPE CELL MIGRATION 28 154 1.095e-06 1.999e-05
256 PROTEIN DEPHOSPHORYLATION 32 190 1.132e-06 2.057e-05
257 REGULATION OF ANATOMICAL STRUCTURE SIZE 60 472 1.137e-06 2.058e-05
258 EYE DEVELOPMENT 46 326 1.191e-06 2.149e-05
259 REGULATION OF SYNAPSE ORGANIZATION 23 113 1.315e-06 2.362e-05
260 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 59 465 1.482e-06 2.652e-05
261 ENDOTHELIUM DEVELOPMENT 20 90 1.512e-06 2.695e-05
262 ARTERY DEVELOPMENT 18 75 1.532e-06 2.721e-05
263 ORGAN GROWTH 17 68 1.619e-06 2.863e-05
264 CELLULAR RESPONSE TO ACID CHEMICAL 30 175 1.66e-06 2.926e-05
265 ANTERIOR POSTERIOR PATTERN SPECIFICATION 32 194 1.806e-06 3.16e-05
266 POSITIVE REGULATION OF TRANSPORT 100 936 1.805e-06 3.16e-05
267 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 53 404 1.85e-06 3.224e-05
268 REGULATION OF ACTIN FILAMENT BASED PROCESS 44 312 2.051e-06 3.56e-05
269 REGULATION OF NUCLEOTIDE CATABOLIC PROCESS 12 36 2.073e-06 3.572e-05
270 MUSCLE CONTRACTION 36 233 2.07e-06 3.572e-05
271 ACTOMYOSIN STRUCTURE ORGANIZATION 18 77 2.307e-06 3.96e-05
272 SECOND MESSENGER MEDIATED SIGNALING 28 160 2.405e-06 4.098e-05
273 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 14 49 2.403e-06 4.098e-05
274 REGULATION OF METAL ION TRANSPORT 45 325 2.603e-06 4.421e-05
275 CELLULAR RESPONSE TO OXYGEN LEVELS 26 143 2.621e-06 4.435e-05
276 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 33 207 2.715e-06 4.578e-05
277 RETINA VASCULATURE DEVELOPMENT IN CAMERA TYPE EYE 8 16 3.062e-06 5.143e-05
278 RHO PROTEIN SIGNAL TRANSDUCTION 14 50 3.134e-06 5.246e-05
279 HEART TRABECULA MORPHOGENESIS 10 26 3.357e-06 5.598e-05
280 LOCOMOTORY BEHAVIOR 30 181 3.395e-06 5.642e-05
281 MUSCLE CELL DEVELOPMENT 24 128 3.603e-06 5.967e-05
282 REGULATION OF MAP KINASE ACTIVITY 44 319 3.71e-06 6.122e-05
283 ENDOTHELIAL CELL DIFFERENTIATION 17 72 3.785e-06 6.223e-05
284 REGULATION OF DENDRITE DEVELOPMENT 23 120 3.88e-06 6.356e-05
285 REGULATION OF NUCLEOTIDE METABOLIC PROCESS 33 211 4.157e-06 6.787e-05
286 IN UTERO EMBRYONIC DEVELOPMENT 43 311 4.478e-06 7.285e-05
287 MODULATION OF SYNAPTIC TRANSMISSION 42 301 4.563e-06 7.399e-05
288 PHOSPHATIDYLINOSITOL METABOLIC PROCESS 31 193 4.598e-06 7.429e-05
289 CELL CELL SIGNALING 84 767 4.778e-06 7.693e-05
290 CHEMICAL HOMEOSTASIS 93 874 4.939e-06 7.897e-05
291 RESPONSE TO EXTERNAL STIMULUS 169 1821 4.925e-06 7.897e-05
292 METANEPHROS DEVELOPMENT 18 81 4.992e-06 7.955e-05
293 SEGMENTATION 19 89 5.159e-06 8.192e-05
294 REGULATION OF PHOSPHOLIPASE C ACTIVITY 12 39 5.37e-06 8.47e-05
295 POSITIVE REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 12 39 5.37e-06 8.47e-05
296 CARDIAC MUSCLE CELL DIFFERENTIATION 17 74 5.641e-06 8.838e-05
297 ACTIN MEDIATED CELL CONTRACTION 17 74 5.641e-06 8.838e-05
298 POSITIVE REGULATION OF PHOSPHOLIPASE ACTIVITY 14 53 6.651e-06 0.0001038
299 REGULATION OF FATTY ACID OXIDATION 10 28 7.332e-06 0.0001141
300 LEUKOCYTE ACTIVATION 52 414 8.19e-06 0.000127
301 CARDIAC MUSCLE TISSUE MORPHOGENESIS 14 54 8.431e-06 0.0001295
302 VENTRICULAR SEPTUM DEVELOPMENT 14 54 8.431e-06 0.0001295
303 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 20 100 8.379e-06 0.0001295
304 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 22 117 8.632e-06 0.0001321
305 REGULATION OF ERK1 AND ERK2 CASCADE 35 238 8.789e-06 0.0001341
306 PERICARDIUM DEVELOPMENT 8 18 9.225e-06 0.0001403
307 NEGATIVE REGULATION OF OSSIFICATION 16 69 9.303e-06 0.000141
308 HOMOPHILIC CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 26 153 9.429e-06 0.0001424
309 EMBRYONIC ORGAN MORPHOGENESIS 39 279 9.463e-06 0.0001425
310 AORTA DEVELOPMENT 12 41 9.575e-06 0.0001437
311 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 46 352 9.64e-06 0.0001442
312 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 22 118 9.951e-06 0.0001484
313 LIPID MODIFICATION 32 210 1.004e-05 0.0001493
314 REGULATION OF CELL SIZE 28 172 1.009e-05 0.0001496
315 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 13 48 1.051e-05 0.0001549
316 CARDIAC MUSCLE CELL CONTRACTION 10 29 1.052e-05 0.0001549
317 MUSCLE ORGAN MORPHOGENESIS 16 70 1.132e-05 0.0001661
318 REGULATION OF NEURON APOPTOTIC PROCESS 30 192 1.141e-05 0.0001669
319 LEUKOCYTE DIFFERENTIATION 40 292 1.191e-05 0.0001737
320 SOMITE DEVELOPMENT 17 78 1.196e-05 0.0001739
321 RESPONSE TO STEROID HORMONE 59 497 1.2e-05 0.000174
322 REGULATION OF LIPID METABOLIC PROCESS 39 282 1.219e-05 0.0001761
323 REGULATION OF CELLULAR CARBOHYDRATE CATABOLIC PROCESS 12 42 1.259e-05 0.0001798
324 AUTONOMIC NERVOUS SYSTEM DEVELOPMENT 12 42 1.259e-05 0.0001798
325 REGULATION OF MUSCLE ADAPTATION 15 63 1.25e-05 0.0001798
326 REGULATION OF CARBOHYDRATE CATABOLIC PROCESS 12 42 1.259e-05 0.0001798
327 REGULATION OF NEURON DEATH 36 252 1.269e-05 0.0001804
328 REGULATION OF ORGAN MORPHOGENESIS 35 242 1.272e-05 0.0001804
329 MEMBRANE DEPOLARIZATION DURING CARDIAC MUSCLE CELL ACTION POTENTIAL 7 14 1.315e-05 0.0001859
330 REGULATION OF DENDRITIC SPINE DEVELOPMENT 14 56 1.33e-05 0.0001875
331 NEGATIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 9 24 1.338e-05 0.0001881
332 REGULATION OF OSTEOBLAST DIFFERENTIATION 21 112 1.436e-05 0.0002013
333 NEGATIVE REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 10 30 1.484e-05 0.0002062
334 POSITIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 10 30 1.484e-05 0.0002062
335 CELLULAR RESPONSE TO VASCULAR ENDOTHELIAL GROWTH FACTOR STIMULUS 10 30 1.484e-05 0.0002062
336 RESPONSE TO INORGANIC SUBSTANCE 57 479 1.565e-05 0.0002167
337 REGULATION OF RESPONSE TO WOUNDING 51 413 1.596e-05 0.0002204
338 CELLULAR CHEMICAL HOMEOSTASIS 65 570 1.616e-05 0.0002225
339 REGULATION OF CELL CYCLE 97 949 1.635e-05 0.0002244
340 REGULATION OF STEM CELL DIFFERENTIATION 21 113 1.655e-05 0.0002264
341 REGULATION OF COENZYME METABOLIC PROCESS 13 50 1.705e-05 0.000232
342 REGULATION OF COFACTOR METABOLIC PROCESS 13 50 1.705e-05 0.000232
343 RETINA DEVELOPMENT IN CAMERA TYPE EYE 23 131 1.76e-05 0.0002387
344 REGULATION OF CYTOPLASMIC TRANSPORT 57 481 1.768e-05 0.0002391
345 WOUND HEALING 56 470 1.786e-05 0.0002409
346 CEREBRAL CORTEX DEVELOPMENT 20 105 1.792e-05 0.000241
347 SYSTEM PROCESS 163 1785 1.821e-05 0.0002441
348 CELL DEATH 101 1001 1.864e-05 0.0002492
349 CARDIAC MUSCLE CELL ACTION POTENTIAL 11 37 1.909e-05 0.0002546
350 RESPONSE TO ALCOHOL 46 362 1.991e-05 0.0002647
351 EMBRYONIC PATTERN SPECIFICATION 14 58 2.049e-05 0.0002716
352 CARDIAC ATRIUM DEVELOPMENT 10 31 2.06e-05 0.0002724
353 NEURAL CREST CELL MIGRATION 13 51 2.15e-05 0.0002825
354 ARTERY MORPHOGENESIS 13 51 2.15e-05 0.0002825
355 LYMPHOCYTE ACTIVATION 44 342 2.206e-05 0.0002892
356 MEMORY 19 98 2.221e-05 0.0002903
357 SECRETION 66 588 2.305e-05 0.0003005
358 CALCIUM MEDIATED SIGNALING 18 90 2.336e-05 0.0003036
359 NEGATIVE REGULATION OF CELL JUNCTION ASSEMBLY 8 20 2.354e-05 0.0003051
360 REPRODUCTIVE SYSTEM DEVELOPMENT 50 408 2.362e-05 0.0003053
361 NEGATIVE REGULATION OF NEURON DEATH 27 171 2.538e-05 0.0003271
362 CELL PROLIFERATION 73 672 2.618e-05 0.0003366
363 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 26 162 2.664e-05 0.0003414
364 POSITIVE REGULATION OF BMP SIGNALING PATHWAY 10 32 2.818e-05 0.0003593
365 ADIPOSE TISSUE DEVELOPMENT 10 32 2.818e-05 0.0003593
366 CELL GROWTH 23 135 2.9e-05 0.0003683
367 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 22 126 2.905e-05 0.0003683
368 CARDIAC MUSCLE ADAPTATION 6 11 3.018e-05 0.0003775
369 MUSCLE HYPERTROPHY IN RESPONSE TO STRESS 6 11 3.018e-05 0.0003775
370 VENTRICULAR TRABECULA MYOCARDIUM MORPHOGENESIS 6 11 3.018e-05 0.0003775
371 POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 19 100 2.988e-05 0.0003775
372 CARDIAC MUSCLE HYPERTROPHY IN RESPONSE TO STRESS 6 11 3.018e-05 0.0003775
373 PROTEIN AUTOPHOSPHORYLATION 29 192 3.041e-05 0.0003793
374 REGULATION OF GLUCOSE IMPORT 14 60 3.091e-05 0.0003835
375 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 14 60 3.091e-05 0.0003835
376 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 25 154 3.102e-05 0.0003839
377 REGULATION OF CELLULAR LOCALIZATION 122 1277 3.218e-05 0.0003972
378 REGULATION OF CELL GROWTH 48 391 3.265e-05 0.0004019
379 MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL 11 39 3.308e-05 0.000405
380 TRABECULA MORPHOGENESIS 11 39 3.308e-05 0.000405
381 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 17 84 3.329e-05 0.0004066
382 CELLULAR RESPONSE TO PEPTIDE 37 274 3.421e-05 0.0004166
383 MULTI MULTICELLULAR ORGANISM PROCESS 31 213 3.443e-05 0.0004183
384 SYMPATHETIC NERVOUS SYSTEM DEVELOPMENT 8 21 3.58e-05 0.0004338
385 REGULATION OF TRANSMEMBRANE TRANSPORT 51 426 3.677e-05 0.0004444
386 SKELETAL MUSCLE ORGAN DEVELOPMENT 23 137 3.689e-05 0.0004447
387 MEMBRANE DEPOLARIZATION 14 61 3.767e-05 0.000453
388 NEGATIVE REGULATION OF JNK CASCADE 10 33 3.803e-05 0.0004549
389 EMBRYONIC EYE MORPHOGENESIS 10 33 3.803e-05 0.0004549
390 HIPPO SIGNALING 9 27 3.995e-05 0.0004762
391 GLYCEROPHOSPHOLIPID METABOLIC PROCESS 39 297 4.012e-05 0.0004762
392 DEVELOPMENTAL CELL GROWTH 16 77 4.007e-05 0.0004762
393 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 26 166 4.097e-05 0.0004851
394 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 20 111 4.15e-05 0.0004901
395 CELL JUNCTION ASSEMBLY 22 129 4.221e-05 0.0004973
396 GLAND DEVELOPMENT 48 395 4.232e-05 0.0004973
397 RESPONSE TO ACID CHEMICAL 41 319 4.243e-05 0.0004974
398 NEGATIVE REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 11 40 4.289e-05 0.0005014
399 SOMITOGENESIS 14 62 4.57e-05 0.000533
400 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 66 602 4.779e-05 0.0005559
401 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 21 121 4.796e-05 0.0005565
402 HORMONE MEDIATED SIGNALING PATHWAY 25 158 4.812e-05 0.0005569
403 RESPONSE TO FLUID SHEAR STRESS 10 34 5.067e-05 0.0005851
404 POSITIVE REGULATION OF CELL ADHESION 46 376 5.143e-05 0.0005924
405 AORTA MORPHOGENESIS 8 22 5.298e-05 0.0006086
406 LEARNING 22 131 5.373e-05 0.0006158
407 NEGATIVE REGULATION OF STRESS ACTIVATED MAPK CASCADE 11 41 5.51e-05 0.0006284
408 NEGATIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 11 41 5.51e-05 0.0006284
409 VENTRICULAR SEPTUM MORPHOGENESIS 9 28 5.539e-05 0.0006302
410 DENDRITE DEVELOPMENT 16 79 5.572e-05 0.0006308
411 REGULATION OF SYNAPSE ASSEMBLY 16 79 5.572e-05 0.0006308
412 CARTILAGE MORPHOGENESIS 6 12 5.694e-05 0.0006431
413 SENSORY ORGAN MORPHOGENESIS 33 239 5.719e-05 0.0006443
414 ODONTOGENESIS 19 105 6.025e-05 0.0006772
415 NEGATIVE REGULATION OF KINASE ACTIVITY 34 250 6.057e-05 0.0006791
416 REGULATION OF STEM CELL PROLIFERATION 17 88 6.201e-05 0.0006936
417 REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 7 17 6.234e-05 0.0006956
418 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 28 190 6.466e-05 0.0007197
419 NEGATIVE REGULATION OF TRANSPORT 53 458 6.506e-05 0.0007225
420 REGULATION OF PHOSPHOLIPASE ACTIVITY 14 64 6.635e-05 0.0007351
421 PHOSPHATIDYLINOSITOL 3 PHOSPHATE BIOSYNTHETIC PROCESS 12 49 6.799e-05 0.0007479
422 REGULATION OF NUCLEOSIDE METABOLIC PROCESS 12 49 6.799e-05 0.0007479
423 REGULATION OF ATP METABOLIC PROCESS 12 49 6.799e-05 0.0007479
424 NEPHRON DEVELOPMENT 20 115 6.982e-05 0.0007663
425 NEGATIVE REGULATION OF GTPASE ACTIVITY 11 42 7.018e-05 0.0007684
426 REGULATION OF CELLULAR COMPONENT SIZE 42 337 7.037e-05 0.0007686
427 REGULATION OF GENERATION OF PRECURSOR METABOLITES AND ENERGY 17 89 7.195e-05 0.0007841
428 REGULATION OF CARBOHYDRATE METABOLIC PROCESS 26 172 7.565e-05 0.0008205
429 POSITIVE REGULATION OF ERK1 AND ERK2 CASCADE 26 172 7.565e-05 0.0008205
430 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 22 134 7.629e-05 0.0008255
431 STRIATED MUSCLE ADAPTATION 8 23 7.649e-05 0.0008258
432 STEROID HORMONE MEDIATED SIGNALING PATHWAY 21 125 7.829e-05 0.0008433
433 REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 15 73 7.928e-05 0.000852
434 REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 12 50 8.408e-05 0.0008973
435 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 48 406 8.4e-05 0.0008973
436 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 12 50 8.408e-05 0.0008973
437 ADULT BEHAVIOR 22 135 8.549e-05 0.0009103
438 DEPHOSPHORYLATION 37 286 8.573e-05 0.0009107
439 SECRETION BY CELL 55 486 8.705e-05 0.0009206
440 POSITIVE REGULATION OF AXON EXTENSION 10 36 8.69e-05 0.0009206
441 REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 11 43 8.867e-05 0.0009355
442 KIDNEY MORPHOGENESIS 16 82 8.923e-05 0.0009394
443 CELL SUBSTRATE ADHESION 25 164 8.978e-05 0.000943
444 LEUKOCYTE CELL CELL ADHESION 34 255 9.016e-05 0.0009448
445 NEGATIVE REGULATION OF MAPK CASCADE 23 145 9.137e-05 0.0009554
446 REGULATION OF DENDRITE MORPHOGENESIS 15 74 9.338e-05 0.0009742
447 POSITIVE REGULATION OF LIPASE ACTIVITY 14 66 9.469e-05 0.0009857
448 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 7 18 9.614e-05 0.0009897
449 ATRIAL SEPTUM DEVELOPMENT 7 18 9.614e-05 0.0009897
450 ENSHEATHMENT OF NEURONS 17 91 9.612e-05 0.0009897
451 AXON ENSHEATHMENT 17 91 9.612e-05 0.0009897
452 GLIAL CELL DIFFERENTIATION 22 136 9.567e-05 0.0009897
453 RESPONSE TO DRUG 50 431 9.732e-05 0.0009997
454 SEMAPHORIN PLEXIN SIGNALING PATHWAY INVOLVED IN NEURON PROJECTION GUIDANCE 6 13 9.977e-05 0.00102
455 NEGATIVE REGULATION OF CARDIAC MUSCLE CELL APOPTOTIC PROCESS 6 13 9.977e-05 0.00102
456 LIMBIC SYSTEM DEVELOPMENT 18 100 0.0001002 0.001022
457 CELL JUNCTION ORGANIZATION 27 185 0.0001024 0.001043
458 NEGATIVE REGULATION OF GROWTH 32 236 0.0001042 0.001059
459 AXON REGENERATION 8 24 0.000108 0.001091
460 EMBRYONIC CAMERA TYPE EYE MORPHOGENESIS 8 24 0.000108 0.001091
461 CARDIAC EPITHELIAL TO MESENCHYMAL TRANSITION 8 24 0.000108 0.001091
462 BRANCHING INVOLVED IN URETERIC BUD MORPHOGENESIS 11 44 0.0001112 0.001117
463 POSITIVE REGULATION OF LIPID METABOLIC PROCESS 21 128 0.0001112 0.001117
464 AXON EXTENSION 10 37 0.000112 0.001123
465 EPITHELIAL CELL DEVELOPMENT 27 186 0.0001124 0.001124
466 POSITIVE REGULATION OF MUSCLE CELL DIFFERENTIATION 16 84 0.0001204 0.001202
467 TUBE FORMATION 21 129 0.0001246 0.001241
468 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 91 926 0.000125 0.001243
469 DIGESTIVE SYSTEM DEVELOPMENT 23 148 0.0001256 0.001246
470 REGULATION OF DNA BINDING 17 93 0.0001271 0.001259
471 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 30 218 0.0001294 0.001279
472 ION HOMEOSTASIS 62 576 0.0001349 0.00133
473 HETEROPHILIC CELL CELL ADHESION VIA PLASMA MEMBRANE CELL ADHESION MOLECULES 11 45 0.0001383 0.001361
474 NEURAL TUBE DEVELOPMENT 23 149 0.0001393 0.001368
475 VENTRICULAR CARDIAC MUSCLE CELL DIFFERENTIATION 7 19 0.0001435 0.0014
476 REGULATION OF CALCIUM ION TRANSPORT 29 209 0.0001438 0.0014
477 REGULATION OF PEPTIDE SECRETION 29 209 0.0001438 0.0014
478 LYMPHOCYTE DIFFERENTIATION 29 209 0.0001438 0.0014
479 ACTION POTENTIAL 17 94 0.0001457 0.001412
480 NEURAL TUBE FORMATION 17 94 0.0001457 0.001412
481 MYELOID CELL DIFFERENTIATION 27 189 0.0001475 0.001427
482 OSSIFICATION 33 251 0.0001488 0.001436
483 HOMEOSTATIC PROCESS 123 1337 0.0001527 0.001468
484 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 30 220 0.0001526 0.001468
485 POSITIVE REGULATION OF AXONOGENESIS 14 69 0.0001567 0.001504
486 POSITIVE REGULATION OF SYNAPSE ASSEMBLY 13 61 0.0001588 0.001517
487 POSITIVE REGULATION OF STEM CELL PROLIFERATION 13 61 0.0001588 0.001517
488 REGULATION OF HEART RATE 16 86 0.0001606 0.001531
489 NEGATIVE REGULATION OF CELL GROWTH 25 170 0.0001611 0.001533
490 REGULATION OF CHEMOTAXIS 26 180 0.0001619 0.001537
491 CELL MIGRATION INVOLVED IN HEART DEVELOPMENT 6 14 0.0001647 0.001539
492 VASCULAR ENDOTHELIAL GROWTH FACTOR SIGNALING PATHWAY 6 14 0.0001647 0.001539
493 NEGATIVE REGULATION OF JUN KINASE ACTIVITY 6 14 0.0001647 0.001539
494 ATRIAL SEPTUM MORPHOGENESIS 6 14 0.0001647 0.001539
495 INSULIN LIKE GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 6 14 0.0001647 0.001539
496 POSITIVE REGULATION OF FATTY ACID OXIDATION 6 14 0.0001647 0.001539
497 NEGATIVE REGULATION OF NUCLEOTIDE CATABOLIC PROCESS 6 14 0.0001647 0.001539
498 ESTABLISHMENT OR MAINTENANCE OF CELL POLARITY 22 141 0.0001645 0.001539
499 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 17 95 0.0001666 0.001554
500 NEGATIVE REGULATION OF DNA BINDING 11 46 0.0001709 0.001588
501 REGULATION OF CHONDROCYTE DIFFERENTIATION 11 46 0.0001709 0.001588
502 MULTICELLULAR ORGANISMAL SIGNALING 20 123 0.0001817 0.001684
503 REGULATION OF FATTY ACID METABOLIC PROCESS 16 87 0.0001848 0.001709
504 FOREBRAIN CELL MIGRATION 13 62 0.0001888 0.001743
505 REGULATION OF PROTEIN LOCALIZATION 92 950 0.0001919 0.001768
506 POSITIVE REGULATION OF PURINE NUCLEOTIDE METABOLIC PROCESS 21 133 0.0001937 0.001777
507 POSITIVE REGULATION OF NUCLEOTIDE METABOLIC PROCESS 21 133 0.0001937 0.001777
508 RAS PROTEIN SIGNAL TRANSDUCTION 22 143 0.0002025 0.001851
509 REGULATION OF CYTOSKELETON ORGANIZATION 55 502 0.0002022 0.001851
510 PLASMA MEMBRANE ORGANIZATION 28 203 0.0002055 0.001875
511 INTRACELLULAR LIPID TRANSPORT 7 20 0.000208 0.001894
512 REGULATION OF INTRACELLULAR TRANSPORT 65 621 0.0002088 0.001897
513 RESPONSE TO CALCIUM ION 19 115 0.0002109 0.001913
514 ESTABLISHMENT OF CELL POLARITY 16 88 0.0002121 0.00192
515 EXOCYTOSIS 38 310 0.0002143 0.001936
516 REGULATION OF PEPTIDE TRANSPORT 33 256 0.000216 0.00194
517 REGULATION OF GLUCOSE METABOLIC PROCESS 18 106 0.0002156 0.00194
518 FAT CELL DIFFERENTIATION 18 106 0.0002156 0.00194
519 REGULATION OF CARTILAGE DEVELOPMENT 13 63 0.0002235 0.002
520 NEUROEPITHELIAL CELL DIFFERENTIATION 13 63 0.0002235 0.002
521 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 36 289 0.0002267 0.002022
522 NEGATIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 10 40 0.0002269 0.002022
523 NEURON PROJECTION REGENERATION 9 33 0.0002284 0.002032
524 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 70 684 0.0002354 0.00209
525 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 21 135 0.0002394 0.002122
526 REGULATION OF BODY FLUID LEVELS 55 506 0.0002471 0.002186
527 GLIOGENESIS 25 175 0.0002552 0.002253
528 RESPONSE TO AXON INJURY 11 48 0.000256 0.002256
529 CELL MIGRATION INVOLVED IN SPROUTING ANGIOGENESIS 6 15 0.0002591 0.002275
530 NEGATIVE REGULATION OF DENDRITE MORPHOGENESIS 6 15 0.0002591 0.002275
531 SMAD PROTEIN SIGNAL TRANSDUCTION 12 56 0.0002667 0.002332
532 EPITHELIAL TO MESENCHYMAL TRANSITION 12 56 0.0002667 0.002332
533 MOTOR NEURON AXON GUIDANCE 8 27 0.0002725 0.002379
534 CELLULAR RESPONSE TO INSULIN STIMULUS 22 146 0.000274 0.002387
535 RESPONSE TO PEPTIDE 46 404 0.0002782 0.002418
536 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 17 99 0.0002785 0.002418
537 POSITIVE REGULATION OF SODIUM ION TRANSPORT 9 34 0.0002923 0.002524
538 REGULATION OF MESENCHYMAL CELL PROLIFERATION 9 34 0.0002923 0.002524
539 HEART VALVE DEVELOPMENT 9 34 0.0002923 0.002524
540 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 27 197 0.0002936 0.00253
541 CIRCADIAN RHYTHM 21 137 0.0002944 0.002532
542 REGULATION OF GLUCOSE TRANSPORT 17 100 0.0003151 0.002705
543 CIRCADIAN REGULATION OF GENE EXPRESSION 12 57 0.0003175 0.002721
544 PEPTIDYL AMINO ACID MODIFICATION 82 841 0.0003425 0.00293
545 POSITIVE REGULATION OF GLUCOSE TRANSPORT 10 42 0.0003486 0.002971
546 EPITHELIAL CELL MORPHOGENESIS 10 42 0.0003486 0.002971
547 MUSCLE HYPERTROPHY 8 28 0.0003593 0.003056
548 RESPONSE TO MONOAMINE 9 35 0.0003705 0.003145
549 PHOSPHOLIPID METABOLIC PROCESS 42 364 0.0003807 0.003227
550 NEGATIVE REGULATION OF ADHERENS JUNCTION ORGANIZATION 6 16 0.0003912 0.00328
551 CARDIAC MYOFIBRIL ASSEMBLY 6 16 0.0003912 0.00328
552 NEURON CELL CELL ADHESION 6 16 0.0003912 0.00328
553 CELLULAR RESPONSE TO LEPTIN STIMULUS 6 16 0.0003912 0.00328
554 POSITIVE REGULATION OF TYROSINE PHOSPHORYLATION OF STAT5 PROTEIN 6 16 0.0003912 0.00328
555 ATRIOVENTRICULAR VALVE MORPHOGENESIS 6 16 0.0003912 0.00328
556 GLUCOSE HOMEOSTASIS 24 170 0.0004011 0.003351
557 CARBOHYDRATE HOMEOSTASIS 24 170 0.0004011 0.003351
558 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 16 93 0.0004073 0.003391
559 NEPHRON EPITHELIUM DEVELOPMENT 16 93 0.0004073 0.003391
560 DIVALENT INORGANIC CATION HOMEOSTASIS 40 343 0.0004184 0.003475
561 RESPONSE TO REACTIVE OXYGEN SPECIES 26 191 0.000419 0.003475
562 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 13 67 0.0004225 0.003498
563 CEREBRAL CORTEX CELL MIGRATION 10 43 0.0004274 0.003532
564 NEGATIVE REGULATION OF BINDING 20 131 0.0004282 0.003533
565 NEGATIVE REGULATION OF GLYCOLYTIC PROCESS 5 11 0.0004324 0.003542
566 NEGATIVE REGULATION OF COENZYME METABOLIC PROCESS 5 11 0.0004324 0.003542
567 NEGATIVE REGULATION OF COFACTOR METABOLIC PROCESS 5 11 0.0004324 0.003542
568 CARDIAC CHAMBER FORMATION 5 11 0.0004324 0.003542
569 CALCIUM ION TRANSPORT 29 223 0.0004375 0.003571
570 NEGATIVE REGULATION OF CELL ADHESION 29 223 0.0004375 0.003571
571 REGULATION OF CALCIUM MEDIATED SIGNALING 14 76 0.00045 0.003667
572 NEUROMUSCULAR JUNCTION DEVELOPMENT 9 36 0.000465 0.003749
573 GLYCEROLIPID METABOLIC PROCESS 41 356 0.0004614 0.003749
574 REGULATION OF HEART MORPHOGENESIS 8 29 0.0004674 0.003749
575 MUSCLE ADAPTATION 8 29 0.0004674 0.003749
576 HEART PROCESS 15 85 0.0004618 0.003749
577 SEMAPHORIN PLEXIN SIGNALING PATHWAY 9 36 0.000465 0.003749
578 NEUROBLAST PROLIFERATION 8 29 0.0004674 0.003749
579 CELLULAR HOMEOSTASIS 68 676 0.0004644 0.003749
580 POSITIVE REGULATION OF GLUCOSE METABOLIC PROCESS 9 36 0.000465 0.003749
581 REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION 27 203 0.0004757 0.00381
582 OVULATION CYCLE 18 113 0.000484 0.00387
583 POSITIVE REGULATION OF WNT SIGNALING PATHWAY 22 152 0.0004858 0.003877
584 NERVE DEVELOPMENT 13 68 0.0004909 0.003911
585 ACTIVATION OF PROTEIN KINASE ACTIVITY 34 279 0.0004999 0.003976
586 T CELL DIFFERENTIATION 19 123 0.0005079 0.004033
587 REGULATION OF SODIUM ION TRANSPORT 14 77 0.0005168 0.004096
588 MYELOID CELL DEVELOPMENT 10 44 0.0005204 0.004118
589 TRANSCRIPTION INITIATION FROM RNA POLYMERASE II PROMOTER 22 153 0.0005323 0.004205
590 INNERVATION 7 23 0.0005512 0.004347
591 RESPONSE TO INSULIN 27 205 0.0005554 0.004373
592 CYCLIC NUCLEOTIDE CATABOLIC PROCESS 6 17 0.0005706 0.004462
593 ANATOMICAL STRUCTURE ARRANGEMENT 6 17 0.0005706 0.004462
594 NEGATIVE REGULATION OF ANOIKIS 6 17 0.0005706 0.004462
595 NEGATIVE REGULATION OF STRIATED MUSCLE CELL APOPTOTIC PROCESS 6 17 0.0005706 0.004462
596 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 28 216 0.000573 0.004473
597 CORONARY VASCULATURE DEVELOPMENT 9 37 0.0005784 0.004493
598 REGULATION OF MUSCLE HYPERTROPHY 9 37 0.0005784 0.004493
599 REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION 9 37 0.0005784 0.004493
600 CELL CYCLE ARREST 22 154 0.0005827 0.004519
601 RENAL TUBULE DEVELOPMENT 14 78 0.0005918 0.004581
602 NEGATIVE REGULATION OF CELL MATRIX ADHESION 8 30 0.0006004 0.004627
603 CELLULAR RESPONSE TO ALCOHOL 18 115 0.0006006 0.004627
604 REGULATION OF DENDRITIC SPINE MORPHOGENESIS 8 30 0.0006004 0.004627
605 SPROUTING ANGIOGENESIS 10 45 0.0006295 0.004834
606 ENDOCHONDRAL BONE MORPHOGENESIS 10 45 0.0006295 0.004834
607 REGULATION OF FAT CELL DIFFERENTIATION 17 106 0.0006338 0.004846
608 NEURON PROJECTION EXTENSION 11 53 0.0006353 0.004846
609 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 11 53 0.0006353 0.004846
610 MESONEPHRIC TUBULE MORPHOGENESIS 11 53 0.0006353 0.004846
611 NEURAL PRECURSOR CELL PROLIFERATION 13 70 0.0006561 0.004988
612 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 13 70 0.0006561 0.004988
613 GLAND MORPHOGENESIS 16 97 0.0006599 0.005009
614 RESPONSE TO CORTICOSTEROID 24 176 0.0006679 0.005062
615 OVULATION CYCLE PROCESS 15 88 0.0006754 0.00511
616 REGULATION OF HORMONE SECRETION 32 262 0.0006929 0.005234
617 EMBRYONIC CAMERA TYPE EYE FORMATION 5 12 0.0007006 0.005283
618 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 9 38 0.0007136 0.005372
619 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 35 296 0.0007252 0.005451
620 REGULATION OF MYELOID CELL APOPTOTIC PROCESS 7 24 0.0007337 0.005488
621 AMMONIUM TRANSMEMBRANE TRANSPORT 7 24 0.0007337 0.005488
622 BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 7 24 0.0007337 0.005488
623 REGULATION OF RECEPTOR ACTIVITY 18 117 0.0007405 0.005531
624 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 41 365 0.0007619 0.005681
625 HINDBRAIN DEVELOPMENT 20 137 0.0007691 0.005726
626 AGING 32 264 0.0007891 0.005866
627 QUATERNARY AMMONIUM GROUP TRANSPORT 6 18 0.0008078 0.005995
628 INTRACELLULAR RECEPTOR SIGNALING PATHWAY 23 168 0.0008096 0.005998
629 MESODERM DEVELOPMENT 18 118 0.0008204 0.006069
630 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 16 99 0.0008298 0.006119
631 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 16 99 0.0008298 0.006119
632 REGULATION OF PHOSPHATASE ACTIVITY 19 128 0.0008383 0.006172
633 PLACENTA DEVELOPMENT 20 138 0.0008442 0.006205
634 REGULATION OF WNT SIGNALING PATHWAY 36 310 0.000855 0.006275
635 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 79 829 0.0008572 0.006281
636 REGULATION OF AXON GUIDANCE 9 39 0.0008734 0.006379
637 COCHLEA DEVELOPMENT 9 39 0.0008734 0.006379
638 REGULATION OF BLOOD PRESSURE 23 169 0.0008793 0.006413
639 CRANIAL SKELETAL SYSTEM DEVELOPMENT 11 55 0.0008822 0.006424
640 SEX DIFFERENTIATION 32 266 0.0008969 0.006521
641 REGULATION OF JNK CASCADE 22 159 0.0009019 0.006547
642 REGULATION OF ION HOMEOSTASIS 26 201 0.0009133 0.006619
643 PEPTIDYL TYROSINE DEPHOSPHORYLATION 16 100 0.0009279 0.006714
644 SALIVARY GLAND DEVELOPMENT 8 32 0.0009576 0.006887
645 ENDOCARDIAL CUSHION DEVELOPMENT 8 32 0.0009576 0.006887
646 REGULATION OF ORGAN FORMATION 8 32 0.0009576 0.006887
647 EMBRYONIC FORELIMB MORPHOGENESIS 8 32 0.0009576 0.006887
648 LUNG CELL DIFFERENTIATION 7 25 0.0009608 0.006889
649 REGULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 7 25 0.0009608 0.006889
650 REGULATION OF RESPONSE TO STRESS 128 1468 0.0009794 0.007011
651 HIPPOCAMPUS DEVELOPMENT 13 73 0.0009903 0.007071
652 INTEGRIN MEDIATED SIGNALING PATHWAY 14 82 0.0009908 0.007071
653 REGULATION OF SYNAPTIC PLASTICITY 20 140 0.001014 0.007222
654 REGULATED EXOCYTOSIS 28 224 0.001016 0.007231
655 RESPONSE TO EXTRACELLULAR STIMULUS 47 441 0.001028 0.007299
656 FATTY ACID TRANSPORT 11 56 0.001033 0.007325
657 FORELIMB MORPHOGENESIS 9 40 0.001061 0.007515
658 REGENERATION 22 161 0.001067 0.007542
659 REGULATION OF VASCULOGENESIS 5 13 0.001076 0.007552
660 DIGESTIVE TRACT MORPHOGENESIS 10 48 0.001075 0.007552
661 MYOFIBRIL ASSEMBLY 10 48 0.001075 0.007552
662 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO PLASMA MEMBRANE 10 48 0.001075 0.007552
663 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORT 10 48 0.001075 0.007552
664 INNER EAR MORPHOGENESIS 15 92 0.001086 0.007611
665 POSITIVE REGULATION OF ION TRANSPORT 29 236 0.001095 0.00766
666 NEGATIVE REGULATION OF AXONOGENESIS 12 65 0.001104 0.007712
667 ION TRANSPORT 112 1262 0.001108 0.007728
668 NEGATIVE REGULATION OF NUCLEOSIDE METABOLIC PROCESS 6 19 0.001114 0.007728
669 PROTEIN STABILIZATION 19 131 0.001114 0.007728
670 NEGATIVE REGULATION OF ATP METABOLIC PROCESS 6 19 0.001114 0.007728
671 ATRIOVENTRICULAR VALVE DEVELOPMENT 6 19 0.001114 0.007728
672 REGULATION OF LIPASE ACTIVITY 14 83 0.00112 0.007755
673 LIPID METABOLIC PROCESS 104 1158 0.001122 0.007755
674 REGULATION OF SECRETION 68 699 0.001132 0.007817
675 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 16 102 0.001154 0.007953
676 EMBRYONIC AXIS SPECIFICATION 8 33 0.001191 0.008161
677 REGULATION OF MUSCLE CELL DIFFERENTIATION 21 152 0.001189 0.008161
678 INTRINSIC APOPTOTIC SIGNALING PATHWAY 21 152 0.001189 0.008161
679 POSITIVE REGULATION OF FATTY ACID METABOLIC PROCESS 8 33 0.001191 0.008161
680 EAR MORPHOGENESIS 17 112 0.001196 0.008187
681 AMMONIUM TRANSPORT 11 57 0.001204 0.008225
682 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 18 122 0.001218 0.008297
683 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 18 122 0.001218 0.008297
684 CELL SUBSTRATE JUNCTION ASSEMBLY 9 41 0.00128 0.008708
685 REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 13 75 0.001284 0.00871
686 CELLULAR GLUCOSE HOMEOSTASIS 13 75 0.001284 0.00871
687 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 21 153 0.001294 0.008762
688 RESPONSE TO OXIDATIVE STRESS 39 352 0.001307 0.008837
689 REGULATION OF LEUKOCYTE PROLIFERATION 26 206 0.001312 0.008858
690 REPRODUCTION 114 1297 0.001402 0.009454
691 POSITIVE REGULATION OF MAP KINASE ACTIVITY 26 207 0.001407 0.009476
692 POSITIVE REGULATION OF PROTEIN IMPORT 16 104 0.001424 0.009576
693 REGULATION OF CATABOLIC PROCESS 70 731 0.001458 0.009773
694 MULTICELLULAR ORGANISM GROWTH 13 76 0.001456 0.009773
NumGOOverlapSizeP ValueAdj. P Value
1 PROTEIN KINASE ACTIVITY 96 640 4.656e-14 2.163e-11
2 ENZYME BINDING 197 1737 3.16e-14 2.163e-11
3 CYTOSKELETAL PROTEIN BINDING 113 819 8.705e-14 2.427e-11
4 KINASE ACTIVITY 115 842 1.045e-13 2.427e-11
5 ACTIN BINDING 68 393 3.371e-13 6.263e-11
6 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 92 629 7.141e-13 1.106e-10
7 MACROMOLECULAR COMPLEX BINDING 162 1399 1.599e-12 2.122e-10
8 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 139 1199 6.79e-11 7.39e-09
9 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 56 328 7.159e-11 7.39e-09
10 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 44 228 1.43e-10 1.328e-08
11 MOLECULAR FUNCTION REGULATOR 151 1353 1.574e-10 1.33e-08
12 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 119 992 2.234e-10 1.729e-08
13 PROTEIN COMPLEX BINDING 113 935 4.227e-10 2.968e-08
14 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 22 70 4.473e-10 2.968e-08
15 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 52 315 1.171e-09 7.251e-08
16 KINASE BINDING 80 606 3.4e-09 1.974e-07
17 RECEPTOR BINDING 156 1476 3.839e-09 2.098e-07
18 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 40 226 1.304e-08 6.731e-07
19 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 19 64 1.968e-08 9.623e-07
20 PROTEIN DOMAIN SPECIFIC BINDING 79 624 2.757e-08 1.28e-06
21 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 21 81 5.013e-08 2.218e-06
22 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 47 303 5.339e-08 2.255e-06
23 REGULATORY REGION NUCLEIC ACID BINDING 95 818 7.774e-08 3.14e-06
24 PROTEIN TYROSINE KINASE ACTIVITY 32 176 1.919e-07 7.427e-06
25 PROTEIN SERINE THREONINE KINASE ACTIVITY 59 445 3.419e-07 1.27e-05
26 GROWTH FACTOR BINDING 25 123 4.748e-07 1.697e-05
27 PHOSPHORIC ESTER HYDROLASE ACTIVITY 51 368 5.56e-07 1.913e-05
28 ZINC ION BINDING 120 1155 6.892e-07 2.287e-05
29 SEQUENCE SPECIFIC DNA BINDING 110 1037 7.642e-07 2.367e-05
30 ADENYL NUCLEOTIDE BINDING 149 1514 7.566e-07 2.367e-05
31 RIBONUCLEOTIDE BINDING 176 1860 9.023e-07 2.704e-05
32 HEPARIN BINDING 28 157 1.633e-06 4.741e-05
33 PHOSPHATIDYLINOSITOL 3 KINASE BINDING 11 30 1.883e-06 5.301e-05
34 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 25 133 2.169e-06 5.927e-05
35 ACTIVATING TRANSCRIPTION FACTOR BINDING 15 57 3.298e-06 8.754e-05
36 DOUBLE STRANDED DNA BINDING 84 764 4.104e-06 0.0001059
37 PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 29 178 6.948e-06 0.0001744
38 TRANSCRIPTION FACTOR BINDING 62 524 8.053e-06 0.0001969
39 SULFUR COMPOUND BINDING 34 234 1.523e-05 0.000356
40 PROTEIN SERINE THREONINE PHOSPHATASE ACTIVITY 15 64 1.533e-05 0.000356
41 SMAD BINDING 16 72 1.655e-05 0.0003576
42 GLYCOSAMINOGLYCAN BINDING 31 205 1.605e-05 0.0003576
43 X1 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 12 43 1.642e-05 0.0003576
44 INTEGRIN BINDING 20 105 1.792e-05 0.0003783
45 COLLAGEN BINDING 15 65 1.871e-05 0.0003863
46 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 66 588 2.305e-05 0.0004656
47 STEROID HORMONE RECEPTOR ACTIVITY 14 59 2.523e-05 0.0004987
48 INSULIN RECEPTOR BINDING 10 32 2.818e-05 0.0005455
49 TRANSCRIPTION COACTIVATOR BINDING 6 11 3.018e-05 0.0005722
50 TUBULIN BINDING 37 273 3.157e-05 0.0005866
51 GROWTH FACTOR RECEPTOR BINDING 22 129 4.221e-05 0.0007689
52 TRANSITION METAL ION BINDING 131 1400 4.311e-05 0.0007702
53 CELL ADHESION MOLECULE BINDING 28 186 4.398e-05 0.0007709
54 CALCIUM ION BINDING 74 697 4.933e-05 0.0008487
55 TRANSCRIPTION FACTOR ACTIVITY DIRECT LIGAND REGULATED SEQUENCE SPECIFIC DNA BINDING 12 48 5.463e-05 0.0009063
56 CHANNEL REGULATOR ACTIVITY 22 131 5.373e-05 0.0009063
57 SIGNALING ADAPTOR ACTIVITY 15 74 9.338e-05 0.001522
58 PHOSPHATIDYLINOSITOL KINASE ACTIVITY 12 51 0.0001033 0.001655
59 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 25 168 0.0001331 0.002096
60 CORECEPTOR ACTIVITY 10 38 0.000143 0.002214
61 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ACTIVITY 8 25 0.0001496 0.002279
62 MICROTUBULE BINDING 28 201 0.0001736 0.002601
63 KINASE INHIBITOR ACTIVITY 16 89 0.0002428 0.00358
64 X3 5 CYCLIC AMP PHOSPHODIESTERASE ACTIVITY 6 15 0.0002591 0.003761
65 ENZYME REGULATOR ACTIVITY 92 959 0.0002649 0.003786
66 PHOSPHORIC DIESTER HYDROLASE ACTIVITY 16 90 0.0002773 0.003845
67 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC BINDING 16 90 0.0002773 0.003845
68 FIBROBLAST GROWTH FACTOR RECEPTOR BINDING 8 28 0.0003593 0.004909
69 PHOSPHATASE ACTIVITY 34 275 0.0003837 0.005143
70 ION CHANNEL BINDING 18 111 0.0003875 0.005143
71 PROTEIN DIMERIZATION ACTIVITY 106 1149 0.0003957 0.005177
72 SEMAPHORIN RECEPTOR ACTIVITY 5 11 0.0004324 0.005579
73 ACTININ BINDING 8 29 0.0004674 0.005948
74 PHOSPHATASE BINDING 23 162 0.0004836 0.006071
75 IDENTICAL PROTEIN BINDING 110 1209 0.0005123 0.006262
76 RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 17 104 0.0005058 0.006262
77 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 15 86 0.0005254 0.006339
78 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II ACTIVATING TRANSCRIPTION FACTOR BINDING 11 53 0.0006353 0.007566
79 PROTEIN HOMODIMERIZATION ACTIVITY 71 722 0.0006633 0.0078
80 GTPASE BINDING 35 295 0.0006821 0.007921
81 PROTEIN TYROSINE KINASE BINDING 11 54 0.0007504 0.008606
82 CALMODULIN BINDING 24 179 0.0008516 0.009648
83 VOLTAGE GATED ION CHANNEL ACTIVITY 25 190 0.0008861 0.009918
NumGOOverlapSizeP ValueAdj. P Value
1 NEURON PART 166 1265 9.343e-18 2.498e-15
2 SYNAPSE 116 754 1.283e-17 2.498e-15
3 NEURON PROJECTION 135 942 1.11e-17 2.498e-15
4 CELL PROJECTION 207 1786 6.203e-16 9.056e-14
5 POSTSYNAPSE 64 378 4.548e-12 4.818e-10
6 SYNAPSE PART 88 610 4.95e-12 4.818e-10
7 CYTOSKELETON 206 1967 1.742e-11 1.453e-09
8 SOMATODENDRITIC COMPARTMENT 88 650 1.494e-10 1.09e-08
9 EXCITATORY SYNAPSE 40 197 1.993e-10 1.293e-08
10 CELL JUNCTION 133 1151 2.27e-10 1.326e-08
11 AXON 64 418 3.682e-10 1.955e-08
12 CELL LEADING EDGE 55 350 2.473e-09 1.204e-07
13 ACTIN CYTOSKELETON 62 444 2.567e-08 1.098e-06
14 MEMBRANE REGION 124 1134 2.632e-08 1.098e-06
15 CELL PROJECTION PART 107 946 4.548e-08 1.681e-06
16 DENDRITE 62 451 4.606e-08 1.681e-06
17 CELL CELL JUNCTION 55 383 6.086e-08 2.091e-06
18 ACTOMYOSIN 18 62 6.802e-08 2.207e-06
19 SITE OF POLARIZED GROWTH 29 149 1.582e-07 4.864e-06
20 PROTEINACEOUS EXTRACELLULAR MATRIX 51 356 1.975e-07 5.766e-06
21 PLASMA MEMBRANE REGION 103 929 2.191e-07 6.092e-06
22 EXTRACELLULAR MATRIX 57 426 3.983e-07 1.057e-05
23 INTRINSIC COMPONENT OF PLASMA MEMBRANE 159 1649 1.076e-06 2.731e-05
24 AXON PART 35 219 1.29e-06 3.14e-05
25 CYTOSKELETAL PART 140 1436 2.806e-06 6.555e-05
26 RECEPTOR COMPLEX 45 327 3.074e-06 6.904e-05
27 SARCOLEMMA 23 125 7.921e-06 0.0001713
28 MEMBRANE MICRODOMAIN 40 288 8.544e-06 0.0001782
29 CELL SURFACE 82 757 9.354e-06 0.0001884
30 CELL BODY 59 494 9.987e-06 0.0001944
31 ACTIN FILAMENT 16 70 1.132e-05 0.0002132
32 PLASMA MEMBRANE PROTEIN COMPLEX 60 510 1.337e-05 0.000244
33 MICROTUBULE CYTOSKELETON 107 1068 1.421e-05 0.0002515
34 NEURON SPINE 22 121 1.507e-05 0.0002589
35 ACTIN FILAMENT BUNDLE 14 57 1.655e-05 0.0002762
36 EXTRACELLULAR MATRIX COMPONENT 22 125 2.557e-05 0.0004147
37 INTRACELLULAR VESICLE 121 1259 2.661e-05 0.0004201
38 SECRETORY VESICLE 53 461 7.722e-05 0.001156
39 LAMELLIPODIUM 26 172 7.565e-05 0.001156
40 CYTOPLASMIC REGION 37 287 9.224e-05 0.001347
41 ANCHORING JUNCTION 55 489 0.0001025 0.001459
42 APICAL JUNCTION COMPLEX 21 128 0.0001112 0.001546
43 CELL CORTEX 32 238 0.0001223 0.001662
44 BASEMENT MEMBRANE 17 93 0.0001271 0.001688
45 T TUBULE 11 45 0.0001383 0.001795
46 I BAND 20 121 0.0001445 0.001834
47 NEURONAL POSTSYNAPTIC DENSITY 12 53 0.0001534 0.001906
48 PLASMA MEMBRANE RAFT 16 86 0.0001606 0.001954
49 CATION CHANNEL COMPLEX 24 167 0.0003069 0.00361
50 SYNAPTIC MEMBRANE 33 261 0.0003091 0.00361
51 PRESYNAPSE 35 283 0.0003156 0.003613
52 SEMAPHORIN RECEPTOR COMPLEX 5 11 0.0004324 0.004856
53 FILOPODIUM 16 94 0.000461 0.00508
54 MICROTUBULE 45 405 0.0005476 0.005922
55 PROTEIN COMPLEX INVOLVED IN CELL ADHESION 8 30 0.0006004 0.006375
56 CELL SUBSTRATE JUNCTION 44 398 0.0006967 0.007138
57 RUFFLE 22 156 0.0006961 0.007138
58 CONTRACTILE FIBER 27 211 0.0008688 0.008748
59 CUL3 RING UBIQUITIN LIGASE COMPLEX 12 64 0.0009572 0.009475

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04151_PI3K_AKT_signaling_pathway 61 351 4.652e-12 8.374e-10
2 hsa04510_Focal_adhesion 41 200 8.673e-11 7.806e-09
3 hsa04010_MAPK_signaling_pathway 46 268 2.985e-09 1.791e-07
4 hsa04514_Cell_adhesion_molecules_.CAMs. 30 136 4.775e-09 2.149e-07
5 hsa04270_Vascular_smooth_muscle_contraction 27 116 8.19e-09 2.948e-07
6 hsa04014_Ras_signaling_pathway 40 236 4.527e-08 1.358e-06
7 hsa04810_Regulation_of_actin_cytoskeleton 36 214 2.549e-07 6.555e-06
8 hsa04360_Axon_guidance 25 130 1.402e-06 3.155e-05
9 hsa04512_ECM.receptor_interaction 19 85 2.501e-06 5.003e-05
10 hsa04310_Wnt_signaling_pathway 26 151 7.381e-06 0.0001329
11 hsa04020_Calcium_signaling_pathway 28 177 1.748e-05 0.000286
12 hsa04971_Gastric_acid_secretion 15 74 9.338e-05 0.001401
13 hsa04720_Long.term_potentiation 14 70 0.000184 0.002548
14 hsa04910_Insulin_signaling_pathway 21 138 0.0003258 0.004189
15 hsa04916_Melanogenesis 17 101 0.0003557 0.004268
16 hsa04390_Hippo_signaling_pathway 22 154 0.0005827 0.006266
17 hsa04070_Phosphatidylinositol_signaling_system 14 78 0.0005918 0.006266
18 hsa04730_Long.term_depression 13 70 0.0006561 0.006561
19 hsa04970_Salivary_secretion 15 89 0.000763 0.007229
20 hsa04912_GnRH_signaling_pathway 16 101 0.001036 0.008876
21 hsa04972_Pancreatic_secretion 16 101 0.001036 0.008876
22 hsa04144_Endocytosis 25 203 0.002258 0.01847
23 hsa04350_TGF.beta_signaling_pathway 13 85 0.004045 0.03165
24 hsa04370_VEGF_signaling_pathway 12 76 0.00433 0.03247
25 hsa04920_Adipocytokine_signaling_pathway 11 68 0.005117 0.03685
26 hsa04540_Gap_junction 13 90 0.006618 0.04582
27 hsa04530_Tight_junction 17 133 0.007377 0.04918
28 hsa04114_Oocyte_meiosis 15 114 0.008815 0.05667
29 hsa04722_Neurotrophin_signaling_pathway 16 127 0.01047 0.06499
30 hsa04660_T_cell_receptor_signaling_pathway 14 108 0.01264 0.07356
31 hsa04012_ErbB_signaling_pathway 12 87 0.01267 0.07356
32 hsa04710_Circadian_rhythm_._mammal 5 23 0.01611 0.09064
33 hsa04960_Aldosterone.regulated_sodium_reabsorption 7 42 0.02007 0.1095
34 hsa04520_Adherens_junction 10 73 0.02273 0.1203
35 hsa02010_ABC_transporters 7 44 0.02542 0.1271
36 hsa04962_Vasopressin.regulated_water_reabsorption 7 44 0.02542 0.1271
37 hsa04662_B_cell_receptor_signaling_pathway 10 75 0.02693 0.131
38 hsa04062_Chemokine_signaling_pathway 20 189 0.0277 0.1312
39 hsa04630_Jak.STAT_signaling_pathway 17 155 0.02982 0.1377
40 hsa04210_Apoptosis 11 89 0.03445 0.155
41 hsa04664_Fc_epsilon_RI_signaling_pathway 10 79 0.03693 0.1621
42 hsa04115_p53_signaling_pathway 9 69 0.0393 0.1665
43 hsa00564_Glycerophospholipid_metabolism 10 80 0.03978 0.1665
44 hsa04670_Leukocyte_transendothelial_migration 13 117 0.04835 0.1978
45 hsa04666_Fc_gamma_R.mediated_phagocytosis 11 95 0.05156 0.2062
46 hsa04150_mTOR_signaling_pathway 7 52 0.05626 0.2202
47 hsa04914_Progesterone.mediated_oocyte_maturation 10 87 0.06405 0.2453
48 hsa04640_Hematopoietic_cell_lineage 10 88 0.06815 0.2556
49 hsa04340_Hedgehog_signaling_pathway 7 56 0.07784 0.2859
50 hsa04320_Dorso.ventral_axis_formation 4 25 0.08161 0.2938
51 hsa00562_Inositol_phosphate_metabolism 7 57 0.08389 0.2961
52 hsa00565_Ether_lipid_metabolism 5 36 0.08903 0.3082
53 hsa00534_Glycosaminoglycan_biosynthesis_._heparan_sulfate 4 26 0.09159 0.3111
54 hsa00561_Glycerolipid_metabolism 6 50 0.1143 0.3809
55 hsa04650_Natural_killer_cell_mediated_cytotoxicity 13 136 0.1216 0.3981
56 hsa00531_Glycosaminoglycan_degradation 3 19 0.1296 0.4166
57 hsa04260_Cardiac_muscle_contraction 8 77 0.1408 0.4445
58 hsa04380_Osteoclast_differentiation 12 128 0.147 0.4562
59 hsa00740_Riboflavin_metabolism 2 11 0.1643 0.5012
60 hsa00532_Glycosaminoglycan_biosynthesis_._chondroitin_sulfate 3 22 0.1784 0.5353
61 hsa03015_mRNA_surveillance_pathway 8 83 0.1887 0.5568
62 hsa00760_Nicotinate_and_nicotinamide_metabolism 3 24 0.2133 0.6194
63 hsa00052_Galactose_metabolism 3 27 0.268 0.7656
64 hsa00600_Sphingolipid_metabolism 4 40 0.2766 0.7778
65 hsa00230_Purine_metabolism 13 162 0.286 0.792
66 hsa00500_Starch_and_sucrose_metabolism 5 54 0.2916 0.7948
67 hsa04974_Protein_digestion_and_absorption 7 81 0.2959 0.7948
68 hsa00071_Fatty_acid_metabolism 4 43 0.3226 0.8539
69 hsa00670_One_carbon_pool_by_folate 2 18 0.3404 0.8879
70 hsa04330_Notch_signaling_pathway 4 47 0.3845 0.9877
71 hsa00592_alpha.Linolenic_acid_metabolism 2 20 0.3896 0.9877
72 hsa00510_N.Glycan_biosynthesis 4 49 0.4153 1
73 hsa04672_Intestinal_immune_network_for_IgA_production 4 49 0.4153 1
74 hsa04130_SNARE_interactions_in_vesicular_transport 3 36 0.4348 1
75 hsa04145_Phagosome 11 156 0.4704 1
76 hsa04110_Cell_cycle 9 128 0.4857 1
77 hsa04976_Bile_secretion 5 71 0.5176 1
78 hsa00590_Arachidonic_acid_metabolism 4 59 0.5611 1
79 hsa04973_Carbohydrate_digestion_and_absorption 3 44 0.5702 1
80 hsa04975_Fat_digestion_and_absorption 3 46 0.6008 1
81 hsa04612_Antigen_processing_and_presentation 5 78 0.6024 1
82 hsa00591_Linoleic_acid_metabolism 2 30 0.6042 1
83 hsa04146_Peroxisome 5 79 0.6138 1
84 hsa00010_Glycolysis_._Gluconeogenesis 4 65 0.6384 1
85 hsa00250_Alanine._aspartate_and_glutamate_metabolism 2 32 0.6397 1
86 hsa00640_Propanoate_metabolism 2 32 0.6397 1
87 hsa04140_Regulation_of_autophagy 2 34 0.6726 1
88 hsa04610_Complement_and_coagulation_cascades 4 69 0.6847 1
89 hsa03320_PPAR_signaling_pathway 4 70 0.6956 1
90 hsa00350_Tyrosine_metabolism 2 41 0.7688 1
91 hsa00310_Lysine_degradation 2 44 0.8019 1
92 hsa00830_Retinol_metabolism 3 64 0.8095 1
93 hsa04620_Toll.like_receptor_signaling_pathway 5 102 0.819 1
94 hsa04120_Ubiquitin_mediated_proteolysis 7 139 0.8276 1
95 hsa00520_Amino_sugar_and_nucleotide_sugar_metabolism 2 48 0.8394 1
96 hsa00980_Metabolism_of_xenobiotics_by_cytochrome_P450 3 71 0.8612 1
97 hsa03018_RNA_degradation 3 71 0.8612 1
98 hsa04622_RIG.I.like_receptor_signaling_pathway 3 71 0.8612 1
99 hsa04742_Taste_transduction 2 52 0.8704 1
100 hsa04141_Protein_processing_in_endoplasmic_reticulum 8 168 0.8797 1
101 hsa00330_Arginine_and_proline_metabolism 2 54 0.8837 1
102 hsa04142_Lysosome 5 121 0.9129 1
103 hsa00982_Drug_metabolism_._cytochrome_P450 2 73 0.9601 1
104 hsa03013_RNA_transport 5 152 0.9773 1
105 hsa04740_Olfactory_transduction 7 388 1 1

Quest ID: eb61c3e382a1d34542184fa94be90d52