Explanation
This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are
presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.
"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.
miRNA-gene regulations
| Num | microRNA | Gene | miRNA log2FC | miRNA pvalue | Gene log2FC | Gene pvalue | Interaction | Correlation beta | Correlation P-value | PMID | Reported in cancer studies |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | hsa-miR-100-5p | ANAPC11 | -0.78 | 0.00022 | 0.58 | 0 | miRNAWalker2 validate | -0.12 | 5.0E-5 | NA | |
| 2 | hsa-miR-542-3p | ANAPC2 | -1.31 | 0 | 0.16 | 0.04274 | miRanda | -0.13 | 0 | NA | |
| 3 | hsa-miR-30a-5p | ANAPC5 | -0.63 | 0.00011 | 0.24 | 4.0E-5 | miRNAWalker2 validate | -0.11 | 0 | NA | |
| 4 | hsa-miR-139-5p | ANAPC7 | -2.11 | 0 | 0.84 | 0 | miRanda | -0.2 | 0 | NA | |
| 5 | hsa-miR-30c-2-3p | ANAPC7 | -1.4 | 0 | 0.84 | 0 | MirTarget | -0.16 | 0 | NA | |
| 6 | hsa-miR-542-3p | ANAPC7 | -1.31 | 0 | 0.84 | 0 | miRanda | -0.19 | 0 | NA | |
| 7 | hsa-miR-30d-3p | ATM | -0.12 | 0.32955 | -0.24 | 0.01738 | mirMAP | -0.14 | 0.00043 | 24345332 | miR-30d has been observed to be significantly down-regulated in human anaplastic thyroid carcinoma ATC and is believed to be an important event in thyroid cell transformation; In this study we found that miR-30d has a critical role in modulating sensitivity of ATC cells to cisplatin a commonly used chemotherapeutic drug for treatment of this neoplasm; Using a mimic of miR-30d we demonstrated that miR-30d could negatively regulate the expression of beclin 1 a key autophagy gene leading to suppression of the cisplatin-activated autophagic response that protects ATC cells from apoptosis; We further showed that inhibition of the beclin 1-mediated autophagy by the miR-30d mimic sensitized ATC cells to cisplatin both in vitro cell culture and in vivo animal xenograft model; These results suggest that dysregulation of miR-30d in ATC cells is responsible for the insensitivity to cisplatin by promoting autophagic survival; Thus miR-30d may be exploited as a potential target for therapeutic intervention in the treatment of ATC |
| 8 | hsa-miR-339-5p | ATM | 0.28 | 0.03557 | -0.24 | 0.01738 | miRanda | -0.1 | 0.00399 | NA | |
| 9 | hsa-miR-455-5p | ATM | -0.27 | 0.05813 | -0.24 | 0.01738 | miRanda | -0.12 | 0.00045 | NA | |
| 10 | hsa-miR-139-5p | BUB1 | -2.11 | 0 | 4.05 | 0 | miRanda | -0.98 | 0 | NA | |
| 11 | hsa-miR-199a-5p | BUB1 | -1.99 | 0 | 4.05 | 0 | miRanda | -0.29 | 0 | NA | |
| 12 | hsa-miR-542-3p | BUB1 | -1.31 | 0 | 4.05 | 0 | miRanda | -0.67 | 0 | NA | |
| 13 | hsa-miR-215-5p | BUB1B | -0.98 | 3.0E-5 | 3.86 | 0 | miRNAWalker2 validate | -0.16 | 0.00993 | NA | |
| 14 | hsa-miR-22-3p | BUB1B | -0.63 | 0 | 3.86 | 0 | miRNAWalker2 validate | -1.6 | 0 | NA | |
| 15 | hsa-miR-486-5p | BUB1B | -1.78 | 0 | 3.86 | 0 | miRanda | -0.42 | 0 | NA | |
| 16 | hsa-miR-139-5p | BUB3 | -2.11 | 0 | 0.48 | 0 | miRanda | -0.12 | 0 | NA | |
| 17 | hsa-let-7a-3p | CCNA2 | -0.57 | 0 | 3.37 | 0 | MirTarget | -0.51 | 4.0E-5 | NA | |
| 18 | hsa-let-7b-3p | CCNA2 | -1.22 | 0 | 3.37 | 0 | MirTarget | -0.73 | 0 | NA | |
| 19 | hsa-let-7b-5p | CCNA2 | -0.96 | 0 | 3.37 | 0 | miRNAWalker2 validate; miRTarBase | -0.52 | 0 | NA | |
| 20 | hsa-let-7f-1-3p | CCNA2 | -0.7 | 0 | 3.37 | 0 | MirTarget | -0.41 | 1.0E-5 | NA | |
| 21 | hsa-miR-130a-3p | CCNA2 | -1.53 | 0 | 3.37 | 0 | miRNATAP | -0.39 | 0 | NA | |
| 22 | hsa-miR-199a-5p | CCNA2 | -1.99 | 0 | 3.37 | 0 | miRanda | -0.27 | 0 | NA | |
| 23 | hsa-miR-22-3p | CCNA2 | -0.63 | 0 | 3.37 | 0 | MirTarget | -1.22 | 0 | 25596928 | The sequence of miR-22 which is conserved in mice rats humans and other mammalians aligns with the sequence of 3'-UTR of CCNA2; Chenodeoxycholic acid treatment and miR-22 mimics reduced CCNA2 protein and increased the number of G0/G1 Huh7 and HCT116 cells; In humans the expression levels of miR-22 and CCNA2 are inversely correlated in liver and colon cancers |
| 24 | hsa-miR-27b-3p | CCNA2 | -0.82 | 0 | 3.37 | 0 | miRNATAP | -0.54 | 0 | NA | |
| 25 | hsa-miR-29a-3p | CCNA2 | -0.86 | 0 | 3.37 | 0 | MirTarget | -0.88 | 0 | NA | |
| 26 | hsa-miR-29b-1-5p | CCNA2 | -0.54 | 0.00103 | 3.37 | 0 | MirTarget | -0.33 | 4.0E-5 | NA | |
| 27 | hsa-miR-29b-3p | CCNA2 | -0.35 | 0.01214 | 3.37 | 0 | MirTarget | -0.59 | 0 | NA | |
| 28 | hsa-miR-29c-3p | CCNA2 | -1.44 | 0 | 3.37 | 0 | MirTarget | -0.92 | 0 | NA | |
| 29 | hsa-miR-486-5p | CCNA2 | -1.78 | 0 | 3.37 | 0 | miRanda | -0.28 | 0 | NA | |
| 30 | hsa-let-7b-5p | CCNB1 | -0.96 | 0 | 3.16 | 0 | miRNAWalker2 validate | -0.54 | 0 | NA | |
| 31 | hsa-miR-139-5p | CCNB1 | -2.11 | 0 | 3.16 | 0 | miRanda | -0.8 | 0 | NA | |
| 32 | hsa-let-7a-5p | CCNB2 | -0.33 | 0.00046 | 4.24 | 0 | miRNAWalker2 validate | -0.45 | 0.00714 | NA | |
| 33 | hsa-let-7b-5p | CCNB2 | -0.96 | 0 | 4.24 | 0 | miRNAWalker2 validate | -0.59 | 0 | NA | |
| 34 | hsa-let-7c-5p | CCNB2 | -1.71 | 0 | 4.24 | 0 | miRNAWalker2 validate | -0.85 | 0 | NA | |
| 35 | hsa-miR-23b-3p | CCNB2 | -0.53 | 0 | 4.24 | 0 | miRNAWalker2 validate | -0.64 | 1.0E-5 | NA | |
| 36 | hsa-miR-339-5p | CCNB3 | 0.28 | 0.03557 | 0.19 | 0.27484 | miRanda | -0.21 | 0.00149 | NA | |
| 37 | hsa-miR-106a-5p | CCND1 | -0.46 | 0.00972 | -0.9 | 1.0E-5 | MirTarget; miRNATAP | -0.26 | 0 | NA | |
| 38 | hsa-miR-106b-5p | CCND1 | 0.65 | 0 | -0.9 | 1.0E-5 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.43 | 0 | NA | |
| 39 | hsa-miR-1266-5p | CCND1 | 1.63 | 0 | -0.9 | 1.0E-5 | MirTarget | -0.23 | 0 | NA | |
| 40 | hsa-miR-15b-5p | CCND1 | 0.23 | 0.08248 | -0.9 | 1.0E-5 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.54 | 0 | NA | |
| 41 | hsa-miR-16-5p | CCND1 | -0.4 | 0.0001 | -0.9 | 1.0E-5 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.31 | 0.00178 | 23991964; 22922827; 18483394 | At the molecular level our results further revealed that cyclin D1 expression was negatively regulated by miR-16;CCND1 has been found to be a target of miR-15a and miR-16-1 through analysis of complementary sequences between microRNAs and CCND1 mRNA; Moreover the transcription of CCND1 is suppressed by miR-15a and miR-16-1 via direct binding to the CCND1 3'-untranslated region 3'-UTR;Truncation in CCND1 mRNA alters miR 16 1 regulation in mantle cell lymphoma; Furthermore we demonstrated that this truncation alters miR-16-1 binding sites and through the use of reporter constructs we were able to show that miR-16-1 regulates CCND1 mRNA expression; This study introduces the role of miR-16-1 in the regulation of CCND1 in MCL |
| 42 | hsa-miR-17-5p | CCND1 | 0.7 | 2.0E-5 | -0.9 | 1.0E-5 | miRNAWalker2 validate; MirTarget; TargetScan; miRNATAP | -0.34 | 0 | 26431674 | Bioinformatics Prediction and In Vitro Analysis Revealed That miR 17 Targets Cyclin D1 mRNA in Triple Negative Breast Cancer Cells; In this study using bioinformatic analyses miR-17 was selected as it targets the 3'UTR of CCND1 gene with the highest score; After lentiviral transduction of miR-17 to the target cells gene expression analysis showed decreased expression of CCND1 gene |
| 43 | hsa-miR-186-5p | CCND1 | -0.06 | 0.53529 | -0.9 | 1.0E-5 | mirMAP | -0.32 | 0.00286 | NA | |
| 44 | hsa-miR-19a-3p | CCND1 | 1.02 | 0 | -0.9 | 1.0E-5 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.28 | 0 | 25985117 | Moreover miR-19a might play inhibitory roles in HCC malignancy via regulating Cyclin D1 expression |
| 45 | hsa-miR-19b-1-5p | CCND1 | -0.28 | 0.07831 | -0.9 | 1.0E-5 | miRNAWalker2 validate; miRTarBase | -0.31 | 0 | NA | |
| 46 | hsa-miR-19b-3p | CCND1 | 0.6 | 0.00017 | -0.9 | 1.0E-5 | miRNATAP | -0.34 | 0 | NA | |
| 47 | hsa-miR-20a-5p | CCND1 | 0.85 | 0 | -0.9 | 1.0E-5 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.33 | 0 | NA | |
| 48 | hsa-miR-20b-5p | CCND1 | 0.46 | 0.02859 | -0.9 | 1.0E-5 | MirTarget; miRNATAP | -0.23 | 0 | NA | |
| 49 | hsa-miR-340-5p | CCND1 | -0 | 0.9685 | -0.9 | 1.0E-5 | mirMAP | -0.32 | 0.00013 | NA | |
| 50 | hsa-miR-425-5p | CCND1 | 0.59 | 2.0E-5 | -0.9 | 1.0E-5 | miRNAWalker2 validate | -0.39 | 0 | NA | |
| 51 | hsa-miR-503-5p | CCND1 | 0.19 | 0.26842 | -0.9 | 1.0E-5 | miRNAWalker2 validate; miRTarBase; MirTarget | -0.16 | 0.00815 | 26047605; 23731275 | MiR 503 inhibited cell proliferation of human breast cancer cells by suppressing CCND1 expression; Overexpression of miR-503 in breast cancer cell lines reduced cell proliferation through inducing G0/G1 cell cycle arrest by targeting CCND1;MicroRNA 503 suppresses proliferation and cell cycle progression of endometrioid endometrial cancer by negatively regulating cyclin D1; CCND1 has a binding sequence of miR-503 within its 3' untranslated region and was confirmed to be a direct target of miR-503 by the fluorescent reporter assays; Increasing the miR-503 level in EEC cells suppressed cell viability colon formation activity and cell-cycle progression and the inhibited oncogenic phenotypes induced by miR-503 were alleviated by ectopic expression of CCND1 without the untranslated region sequence; Collectively this study suggested that miR-503 plays a tumor-suppressor role by targeting CCND1; Abnormal suppression of miR-503 leads to an increase in the CCND1 level which may promote carcinogenesis and progression of EEC |
| 52 | hsa-miR-589-3p | CCND1 | 1.17 | 0 | -0.9 | 1.0E-5 | MirTarget | -0.18 | 0.00124 | NA | |
| 53 | hsa-miR-616-5p | CCND1 | 0.15 | 0.40284 | -0.9 | 1.0E-5 | mirMAP | -0.26 | 1.0E-5 | NA | |
| 54 | hsa-miR-7-1-3p | CCND1 | -0.57 | 2.0E-5 | -0.9 | 1.0E-5 | mirMAP | -0.26 | 0.00057 | NA | |
| 55 | hsa-miR-9-5p | CCND1 | 1.26 | 9.0E-5 | -0.9 | 1.0E-5 | miRNAWalker2 validate | -0.14 | 1.0E-5 | NA | |
| 56 | hsa-miR-92a-3p | CCND1 | 0.21 | 0.13429 | -0.9 | 1.0E-5 | miRNAWalker2 validate | -0.41 | 0 | NA | |
| 57 | hsa-miR-93-5p | CCND1 | 1.4 | 0 | -0.9 | 1.0E-5 | miRNAWalker2 validate; MirTarget; miRNATAP | -0.34 | 0 | NA | |
| 58 | hsa-miR-942-5p | CCND1 | 0.35 | 0.02833 | -0.9 | 1.0E-5 | MirTarget | -0.25 | 0.00012 | NA | |
| 59 | hsa-miR-130b-5p | CCND2 | 0.17 | 0.33761 | 0.36 | 0.03656 | mirMAP | -0.17 | 0.00018 | NA | |
| 60 | hsa-miR-20a-5p | CCND2 | 0.85 | 0 | 0.36 | 0.03656 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.16 | 0.00121 | NA | |
| 61 | hsa-miR-28-5p | CCND2 | -0.43 | 0 | 0.36 | 0.03656 | miRanda | -0.48 | 0 | NA | |
| 62 | hsa-miR-33a-3p | CCND2 | -0.68 | 1.0E-5 | 0.36 | 0.03656 | MirTarget | -0.26 | 0 | NA | |
| 63 | hsa-miR-3607-3p | CCND2 | -2.16 | 0 | 0.36 | 0.03656 | mirMAP | -0.12 | 0.0007 | NA | |
| 64 | hsa-miR-378a-3p | CCND2 | -1.19 | 0 | 0.36 | 0.03656 | miRNAWalker2 validate | -0.18 | 2.0E-5 | NA | |
| 65 | hsa-miR-548v | CCND2 | -0.27 | 0.17626 | 0.36 | 0.03656 | MirTarget | -0.15 | 0.00034 | NA | |
| 66 | hsa-miR-616-5p | CCND2 | 0.15 | 0.40284 | 0.36 | 0.03656 | mirMAP | -0.32 | 0 | NA | |
| 67 | hsa-miR-618 | CCND2 | 0.14 | 0.51715 | 0.36 | 0.03656 | mirMAP | -0.23 | 0 | NA | |
| 68 | hsa-miR-27b-3p | CCND3 | -0.82 | 0 | 0.08 | 0.47843 | miRNAWalker2 validate | -0.24 | 0 | NA | |
| 69 | hsa-miR-320a | CCND3 | 0.33 | 0.02214 | 0.08 | 0.47843 | miRanda | -0.12 | 0.00135 | NA | |
| 70 | hsa-miR-125b-5p | CCNE1 | -1.36 | 0 | 3.05 | 0 | miRNAWalker2 validate | -0.8 | 0 | NA | |
| 71 | hsa-miR-192-5p | CCNE1 | -0.5 | 0.00345 | 3.05 | 0 | miRNAWalker2 validate | -0.35 | 2.0E-5 | NA | |
| 72 | hsa-miR-195-5p | CCNE1 | -1.86 | 0 | 3.05 | 0 | miRNAWalker2 validate; MirTarget; miRNATAP | -0.3 | 4.0E-5 | 24402230 | Furthermore through qPCR and western blot assays we showed that overexpression of miR-195-5p reduced CCNE1 mRNA and protein levels respectively |
| 73 | hsa-miR-26a-5p | CCNE1 | -0.96 | 0 | 3.05 | 0 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.6 | 2.0E-5 | 22094936 | Cell cycle regulation and CCNE1 and CDC2 were the only significant overlapping pathway and genes differentially expressed between tumors with high and low levels of miR-26a and EZH2 respectively; Low mRNA levels of EZH2 CCNE1 and CDC2 and high levels of miR-26a are associated with favorable outcome on tamoxifen |
| 74 | hsa-miR-26b-5p | CCNE1 | -1.11 | 0 | 3.05 | 0 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.89 | 0 | NA | |
| 75 | hsa-miR-424-5p | CCNE1 | -2.63 | 0 | 3.05 | 0 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.37 | 0 | NA | |
| 76 | hsa-miR-497-5p | CCNE1 | -1.41 | 0 | 3.05 | 0 | MirTarget; miRNATAP | -0.27 | 0.00125 | 24112607; 25909221; 24909281 | Western blot assays confirmed that overexpression of miR-497 reduced cyclin E1 protein levels; Inhibited cellular growth suppressed cellular migration and invasion and G1 cell cycle arrest were observed upon overexpression of miR-497 in cells possibly by targeting cyclin E1;The effect of simultaneous overexpression of miR-497 and miR-34a on the inhibition of cell proliferation colony formation and tumor growth and the downregulation of cyclin E1 was stronger than the effect of each miRNA alone; The synergistic actions of miR-497 and miR-34a partly correlated with cyclin E1 levels; These results indicate cyclin E1 is downregulated by both miR-497 and miR-34a which synergistically retard the growth of human lung cancer cells;miR 497 suppresses proliferation of human cervical carcinoma HeLa cells by targeting cyclin E1; Furthermore the target effect of miR-497 on the CCNE1 was identified by dual-luciferase reporter assay system qRT-PCR and Western blotting; Over-expressed miR-497 in HeLa cells could suppress cell proliferation by targeting CCNE1 |
| 77 | hsa-let-7b-3p | CCNE2 | -1.22 | 0 | 2.02 | 0 | mirMAP | -0.27 | 0.00021 | NA | |
| 78 | hsa-miR-126-3p | CCNE2 | -0.65 | 0 | 2.02 | 0 | miRNAWalker2 validate | -0.39 | 5.0E-5 | NA | |
| 79 | hsa-miR-26a-5p | CCNE2 | -0.96 | 0 | 2.02 | 0 | miRNAWalker2 validate; miRTarBase; miRNATAP | -0.49 | 0 | 24116110; 21901171 | The loss of miR 26a mediated post transcriptional regulation of cyclin E2 in pancreatic cancer cell proliferation and decreased patient survival; The in vitro and in vivo assays showed that overexpression of miR-26a resulted in cell cycle arrest inhibited cell proliferation and decreased tumor growth which was associated with cyclin E2 downregulation;We also show that enforced expression of miR-26a in AML cells is able to inhibit cell cycle progression by downregulating cyclin E2 expression |
| 80 | hsa-miR-26b-5p | CCNE2 | -1.11 | 0 | 2.02 | 0 | miRNATAP | -0.58 | 0 | NA | |
| 81 | hsa-miR-30a-5p | CCNE2 | -0.63 | 0.00011 | 2.02 | 0 | miRNATAP | -0.36 | 0 | NA | |
| 82 | hsa-miR-1301-3p | CCNH | 1.12 | 0 | -0.44 | 0 | miRNAWalker2 validate | -0.15 | 0 | NA | |
| 83 | hsa-miR-23a-3p | CCNH | -0.18 | 0.13598 | -0.44 | 0 | MirTarget | -0.13 | 0.00012 | NA | |
| 84 | hsa-miR-103a-2-5p | CDC14B | 1.17 | 0 | -1.19 | 0 | MirTarget | -0.26 | 0 | NA | |
| 85 | hsa-miR-141-3p | CDC14B | -0.35 | 0.257 | -1.19 | 0 | mirMAP | -0.2 | 0 | NA | |
| 86 | hsa-miR-148b-5p | CDC14B | 0.3 | 0.02557 | -1.19 | 0 | mirMAP | -0.47 | 0 | NA | |
| 87 | hsa-miR-15a-5p | CDC14B | 0.35 | 0.00077 | -1.19 | 0 | miRNAWalker2 validate; MirTarget | -0.26 | 0.00256 | NA | |
| 88 | hsa-miR-15b-5p | CDC14B | 0.23 | 0.08248 | -1.19 | 0 | MirTarget | -0.3 | 1.0E-5 | NA | |
| 89 | hsa-miR-17-3p | CDC14B | 0.41 | 0.00422 | -1.19 | 0 | MirTarget | -0.41 | 0 | NA | |
| 90 | hsa-miR-183-5p | CDC14B | 2.33 | 0 | -1.19 | 0 | MirTarget | -0.21 | 0 | NA | |
| 91 | hsa-miR-185-5p | CDC14B | 0.48 | 0 | -1.19 | 0 | MirTarget | -0.44 | 0 | NA | |
| 92 | hsa-miR-19b-1-5p | CDC14B | -0.28 | 0.07831 | -1.19 | 0 | mirMAP | -0.2 | 0.00069 | NA | |
| 93 | hsa-miR-200a-3p | CDC14B | -1.5 | 3.0E-5 | -1.19 | 0 | mirMAP | -0.15 | 0 | NA | |
| 94 | hsa-miR-21-3p | CDC14B | -0.48 | 0.003 | -1.19 | 0 | mirMAP | -0.3 | 0 | NA | |
| 95 | hsa-miR-27a-3p | CDC14B | -0.37 | 0.00876 | -1.19 | 0 | miRNATAP | -0.28 | 1.0E-5 | NA | |
| 96 | hsa-miR-320a | CDC14B | 0.33 | 0.02214 | -1.19 | 0 | mirMAP | -0.2 | 0.00147 | NA | |
| 97 | hsa-miR-320b | CDC14B | 0.09 | 0.60798 | -1.19 | 0 | mirMAP | -0.21 | 5.0E-5 | NA | |
| 98 | hsa-miR-338-5p | CDC14B | -0.22 | 0.25239 | -1.19 | 0 | PITA | -0.27 | 0 | NA | |
| 99 | hsa-miR-429 | CDC14B | -1.4 | 7.0E-5 | -1.19 | 0 | PITA; miRanda; miRNATAP | -0.15 | 0 | NA | |
| 100 | hsa-miR-501-3p | CDC14B | 1 | 0 | -1.19 | 0 | PITA | -0.47 | 0 | NA | |
| 101 | hsa-miR-502-3p | CDC14B | 0.66 | 0 | -1.19 | 0 | PITA | -0.38 | 0 | NA | |
| 102 | hsa-miR-589-3p | CDC14B | 1.17 | 0 | -1.19 | 0 | mirMAP | -0.33 | 0 | NA | |
| 103 | hsa-miR-590-5p | CDC14B | -0.1 | 0.31003 | -1.19 | 0 | miRanda | -0.36 | 5.0E-5 | NA | |
| 104 | hsa-miR-9-5p | CDC14B | 1.26 | 9.0E-5 | -1.19 | 0 | MirTarget | -0.11 | 5.0E-5 | NA | |
| 105 | hsa-miR-192-5p | CDC20 | -0.5 | 0.00345 | 4.44 | 0 | miRNAWalker2 validate | -0.26 | 0.00747 | NA | |
| 106 | hsa-miR-215-5p | CDC20 | -0.98 | 3.0E-5 | 4.44 | 0 | miRNAWalker2 validate | -0.21 | 0.0025 | NA | |
| 107 | hsa-miR-23b-3p | CDC20 | -0.53 | 0 | 4.44 | 0 | miRNAWalker2 validate | -0.73 | 0 | NA | |
| 108 | hsa-miR-30a-5p | CDC20 | -0.63 | 0.00011 | 4.44 | 0 | miRNAWalker2 validate | -0.69 | 0 | NA | |
| 109 | hsa-miR-29c-3p | CDC23 | -1.44 | 0 | 0.46 | 0 | miRNAWalker2 validate | -0.14 | 0 | NA | |
| 110 | hsa-let-7b-5p | CDC25A | -0.96 | 0 | 1.92 | 0 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.37 | 0 | NA | |
| 111 | hsa-let-7c-5p | CDC25A | -1.71 | 0 | 1.92 | 0 | MirTarget | -0.52 | 0 | 25909324 | MicroRNA let 7c Inhibits Cell Proliferation and Induces Cell Cycle Arrest by Targeting CDC25A in Human Hepatocellular Carcinoma; The aim of the present study was to determine whether the cell cycle regulator CDC25A is involved in the antitumor effect of let-7c in HCC; The luciferase reporter assay showed that CDC25A was a direct target of let-7c and that let-7c inhibited the expression of CDC25A protein by directly targeting its 3' UTR; In conclusion this study indicates that let-7c suppresses HCC progression possibly by directly targeting the cell cycle regulator CDC25A and indirectly affecting its downstream target molecules |
| 112 | hsa-let-7g-5p | CDC25A | -0.46 | 2.0E-5 | 1.92 | 0 | MirTarget; miRNATAP | -0.34 | 0.00089 | NA | |
| 113 | hsa-miR-193b-3p | CDC25A | -0.17 | 0.27202 | 1.92 | 0 | miRNAWalker2 validate | -0.24 | 0.00099 | NA | |
| 114 | hsa-miR-195-5p | CDC25A | -1.86 | 0 | 1.92 | 0 | MirTarget; miRNATAP | -0.35 | 0 | NA | |
| 115 | hsa-miR-30b-3p | CDC25A | -0.44 | 0.00095 | 1.92 | 0 | MirTarget | -0.29 | 0.00054 | NA | |
| 116 | hsa-miR-424-5p | CDC25A | -2.63 | 0 | 1.92 | 0 | miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP | -0.29 | 0 | NA | |
| 117 | hsa-miR-497-5p | CDC25A | -1.41 | 0 | 1.92 | 0 | MirTarget; miRNATAP | -0.35 | 0 | NA | |
| 118 | hsa-let-7a-5p | CDC25B | -0.33 | 0.00046 | 0.8 | 0 | miRNAWalker2 validate | -0.21 | 0.00571 | NA | |
| 119 | hsa-miR-148a-3p | CDC25B | -0.75 | 0 | 0.8 | 0 | miRNAWalker2 validate; miRNATAP | -0.29 | 0 | 25341915 | Gene CDC25B might be the target gene of miR-148a according to the results of targetscan; CDC25B may be the target gene of miR-148a that plays a role in tumor suppressor |
| 120 | hsa-miR-204-5p | CDC25B | -0.54 | 0.03309 | 0.8 | 0 | miRNATAP | -0.16 | 0 | NA | |
| 121 | hsa-miR-26b-5p | CDC25B | -1.11 | 0 | 0.8 | 0 | miRNAWalker2 validate | -0.28 | 0 | NA | |
| 122 | hsa-miR-27b-3p | CDC25B | -0.82 | 0 | 0.8 | 0 | miRNATAP | -0.3 | 0 | NA | |
| 123 | hsa-miR-142-3p | CDC25C | -1.42 | 0 | 4.75 | 0 | miRanda | -0.32 | 0.00029 | NA | |
| 124 | hsa-miR-142-3p | CDC6 | -1.42 | 0 | 3.43 | 0 | miRNAWalker2 validate | -0.21 | 0.0024 | NA | |
| 125 | hsa-miR-199a-5p | CDC6 | -1.99 | 0 | 3.43 | 0 | miRanda | -0.27 | 0 | NA | |
| 126 | hsa-miR-26a-5p | CDC6 | -0.96 | 0 | 3.43 | 0 | miRNAWalker2 validate | -0.79 | 0 | 25100863; 27158389 | Here it is demonstrated that miR26a and miR26b inhibit replication licensing and the proliferation migration and invasion of lung cancer cells by targeting CDC6; The current study suggests that miR26a miR26b and CDC6 and factors regulating their expression represent potential cancer diagnostic and prognostic markers as well as anticancer targets;miR 26a inhibits the proliferation of ovarian cancer cells via regulating CDC6 expression; Bioinformatics analysis revealed Cdc6 was a target gene of miR-26a; dual-luciferase assay and validation assay showed miR-26a could act on the 3'UTR of Cdc6 to regulate Cdc6 expression; These findings suggest that miR-26a may act on the 3'UTR of Cdc6 to regulate Cdc6 expression which then inhibit the proliferation of ovarian cancer cells and induce their apoptosis |
| 127 | hsa-miR-3607-3p | CDC6 | -2.16 | 0 | 3.43 | 0 | mirMAP | -0.42 | 0 | NA | |
| 128 | hsa-miR-101-3p | CDC7 | -1.48 | 0 | 2.02 | 0 | miRNAWalker2 validate | -0.62 | 0 | NA | |
| 129 | hsa-miR-126-5p | CDC7 | -0.43 | 7.0E-5 | 2.02 | 0 | mirMAP | -0.39 | 1.0E-5 | NA | |
| 130 | hsa-miR-192-5p | CDC7 | -0.5 | 0.00345 | 2.02 | 0 | miRNAWalker2 validate | -0.2 | 0.00036 | NA | |
| 131 | hsa-miR-199a-5p | CDC7 | -1.99 | 0 | 2.02 | 0 | MirTarget; miRanda | -0.11 | 0.00038 | NA | |
| 132 | hsa-miR-215-5p | CDC7 | -0.98 | 3.0E-5 | 2.02 | 0 | miRNAWalker2 validate | -0.11 | 0.00749 | NA | |
| 133 | hsa-miR-3065-3p | CDC7 | -1.04 | 5.0E-5 | 2.02 | 0 | MirTarget | -0.13 | 0.00068 | NA | |
| 134 | hsa-miR-335-5p | CDC7 | -1.61 | 0 | 2.02 | 0 | MirTarget | -0.18 | 0.00032 | NA | |
| 135 | hsa-miR-3607-3p | CDC7 | -2.16 | 0 | 2.02 | 0 | miRNATAP | -0.28 | 0 | NA | |
| 136 | hsa-miR-122-5p | CDK4 | -1.24 | 0 | 0.67 | 0 | miRNAWalker2 validate | -0.12 | 0 | NA | |
| 137 | hsa-miR-145-5p | CDK4 | -1.48 | 0 | 0.67 | 0 | miRNAWalker2 validate; miRTarBase | -0.15 | 0 | 21092188 | Furthermore we found that CDK4 was regulated by miR-145 in cell cycle control |
| 138 | hsa-miR-193b-3p | CDK4 | -0.17 | 0.27202 | 0.67 | 0 | miRNAWalker2 validate | -0.15 | 0 | NA | |
| 139 | hsa-miR-195-5p | CDK4 | -1.86 | 0 | 0.67 | 0 | miRNAWalker2 validate; miRTarBase | -0.18 | 0 | NA | |
| 140 | hsa-let-7a-3p | CDK6 | -0.57 | 0 | -0.31 | 0.22057 | miRNATAP | -0.34 | 0.00261 | NA | |
| 141 | hsa-let-7b-5p | CDK6 | -0.96 | 0 | -0.31 | 0.22057 | miRNAWalker2 validate; miRTarBase | -0.22 | 0.00756 | NA | |
| 142 | hsa-miR-106a-5p | CDK6 | -0.46 | 0.00972 | -0.31 | 0.22057 | mirMAP | -0.28 | 4.0E-5 | NA | |
| 143 | hsa-miR-106b-5p | CDK6 | 0.65 | 0 | -0.31 | 0.22057 | mirMAP | -0.39 | 0.00029 | NA | |
| 144 | hsa-miR-141-3p | CDK6 | -0.35 | 0.257 | -0.31 | 0.22057 | TargetScan; miRNATAP | -0.14 | 0.00031 | NA | |
| 145 | hsa-miR-148b-3p | CDK6 | 0.27 | 0.00185 | -0.31 | 0.22057 | mirMAP | -0.76 | 0 | NA | |
| 146 | hsa-miR-16-5p | CDK6 | -0.4 | 0.0001 | -0.31 | 0.22057 | miRNAWalker2 validate; miRTarBase | -0.5 | 3.0E-5 | NA | |
| 147 | hsa-miR-17-5p | CDK6 | 0.7 | 2.0E-5 | -0.31 | 0.22057 | TargetScan; mirMAP | -0.33 | 0 | NA | |
| 148 | hsa-miR-182-5p | CDK6 | 1.97 | 0 | -0.31 | 0.22057 | mirMAP | -0.11 | 0.00279 | NA | |
| 149 | hsa-miR-195-5p | CDK6 | -1.86 | 0 | -0.31 | 0.22057 | miRNAWalker2 validate; miRTarBase | -0.26 | 2.0E-5 | 23333942 | Expression of cyclin-dependent kinase 6 and vascular endothelial growth factor was down-regulated by exogenous miR-195 and miR-378 respectively |
| 150 | hsa-miR-200c-3p | CDK6 | -0.1 | 0.71696 | -0.31 | 0.22057 | mirMAP | -0.12 | 0.00446 | NA |
| Num | GO | Overlap | Size | P Value | Adj. P Value |
|---|---|---|---|---|---|
| 1 | CELL CYCLE | 78 | 1316 | 3.9e-78 | 1.815e-74 |
| 2 | MITOTIC CELL CYCLE | 67 | 766 | 6.181e-75 | 1.438e-71 |
| 3 | CELL CYCLE PROCESS | 72 | 1081 | 1.75e-73 | 2.714e-70 |
| 4 | REGULATION OF CELL CYCLE | 69 | 949 | 4.123e-72 | 4.796e-69 |
| 5 | CELL CYCLE PHASE TRANSITION | 42 | 255 | 1.359e-55 | 1.265e-52 |
| 6 | REGULATION OF MITOTIC CELL CYCLE | 47 | 468 | 3.423e-52 | 2.655e-49 |
| 7 | REGULATION OF CELL CYCLE PHASE TRANSITION | 42 | 321 | 3.938e-51 | 2.617e-48 |
| 8 | REGULATION OF CELL CYCLE PROCESS | 48 | 558 | 3.989e-50 | 2.32e-47 |
| 9 | NEGATIVE REGULATION OF CELL CYCLE | 43 | 433 | 4.229e-47 | 2.186e-44 |
| 10 | NEGATIVE REGULATION OF CELL CYCLE PROCESS | 33 | 214 | 4.347e-42 | 1.685e-39 |
| 11 | CELL CYCLE G1 S PHASE TRANSITION | 28 | 111 | 4.215e-42 | 1.685e-39 |
| 12 | G1 S TRANSITION OF MITOTIC CELL CYCLE | 28 | 111 | 4.215e-42 | 1.685e-39 |
| 13 | CELL CYCLE CHECKPOINT | 32 | 194 | 9.119e-42 | 3.264e-39 |
| 14 | CELL DIVISION | 40 | 460 | 3.429e-41 | 1.14e-38 |
| 15 | NEGATIVE REGULATION OF MITOTIC CELL CYCLE | 31 | 199 | 1.345e-39 | 4.173e-37 |
| 16 | MITOTIC CELL CYCLE CHECKPOINT | 28 | 139 | 4.716e-39 | 1.371e-36 |
| 17 | REGULATION OF PROTEIN MODIFICATION PROCESS | 56 | 1710 | 1.483e-36 | 4.06e-34 |
| 18 | REGULATION OF TRANSFERASE ACTIVITY | 46 | 946 | 1.969e-36 | 5.09e-34 |
| 19 | NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION | 26 | 146 | 1.027e-34 | 2.516e-32 |
| 20 | POSITIVE REGULATION OF CELL CYCLE | 32 | 332 | 5.695e-34 | 1.325e-31 |
| 21 | POSITIVE REGULATION OF CELL CYCLE PROCESS | 28 | 247 | 1.245e-31 | 2.758e-29 |
| 22 | DNA INTEGRITY CHECKPOINT | 22 | 146 | 1.145e-27 | 2.422e-25 |
| 23 | MITOTIC NUCLEAR DIVISION | 28 | 361 | 6.005e-27 | 1.215e-24 |
| 24 | REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY | 19 | 97 | 2.849e-26 | 5.523e-24 |
| 25 | NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION | 19 | 98 | 3.522e-26 | 6.555e-24 |
| 26 | REGULATION OF CELL CYCLE G1 S PHASE TRANSITION | 21 | 147 | 6.539e-26 | 1.17e-23 |
| 27 | POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS | 44 | 1492 | 1.531e-25 | 2.638e-23 |
| 28 | REGULATION OF CELL CYCLE ARREST | 19 | 108 | 2.59e-25 | 4.304e-23 |
| 29 | REGULATION OF PHOSPHORUS METABOLIC PROCESS | 45 | 1618 | 3.775e-25 | 6.058e-23 |
| 30 | G1 DNA DAMAGE CHECKPOINT | 17 | 73 | 5.579e-25 | 8.653e-23 |
| 31 | POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS | 39 | 1135 | 1.05e-24 | 1.577e-22 |
| 32 | ORGANELLE FISSION | 29 | 496 | 2.044e-24 | 2.972e-22 |
| 33 | CHROMOSOME ORGANIZATION | 37 | 1009 | 2.642e-24 | 3.725e-22 |
| 34 | MITOTIC DNA INTEGRITY CHECKPOINT | 18 | 100 | 3.321e-24 | 4.545e-22 |
| 35 | POSITIVE REGULATION OF CELL CYCLE ARREST | 17 | 85 | 9.658e-24 | 1.284e-21 |
| 36 | CELLULAR RESPONSE TO DNA DAMAGE STIMULUS | 32 | 720 | 2.384e-23 | 3.082e-21 |
| 37 | NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS | 37 | 1087 | 3.5e-23 | 4.401e-21 |
| 38 | SIGNAL TRANSDUCTION IN RESPONSE TO DNA DAMAGE | 17 | 96 | 9.063e-23 | 1.11e-20 |
| 39 | REGULATION OF PROTEIN CATABOLIC PROCESS | 25 | 393 | 6.663e-22 | 7.95e-20 |
| 40 | NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS | 29 | 616 | 8.872e-22 | 1.032e-19 |
| 41 | REGULATION OF CELL DIVISION | 22 | 272 | 1.456e-21 | 1.652e-19 |
| 42 | CELL CYCLE G2 M PHASE TRANSITION | 18 | 138 | 1.53e-21 | 1.695e-19 |
| 43 | REGULATION OF KINASE ACTIVITY | 31 | 776 | 3.154e-21 | 3.413e-19 |
| 44 | REGULATION OF ORGANELLE ORGANIZATION | 36 | 1178 | 6.063e-21 | 6.412e-19 |
| 45 | POSITIVE REGULATION OF TRANSFERASE ACTIVITY | 28 | 616 | 1.326e-20 | 1.371e-18 |
| 46 | DNA METABOLIC PROCESS | 30 | 758 | 2.099e-20 | 2.123e-18 |
| 47 | REGULATION OF NUCLEAR DIVISION | 18 | 163 | 3.373e-20 | 3.339e-18 |
| 48 | POSITIVE REGULATION OF PROTEOLYSIS | 23 | 363 | 4.04e-20 | 3.916e-18 |
| 49 | REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS | 21 | 274 | 4.128e-20 | 3.919e-18 |
| 50 | REGULATION OF PROTEOLYSIS | 29 | 711 | 4.614e-20 | 4.294e-18 |
| 51 | REGULATION OF SISTER CHROMATID SEGREGATION | 14 | 67 | 5.431e-20 | 4.955e-18 |
| 52 | NEGATIVE REGULATION OF TRANSFERASE ACTIVITY | 22 | 351 | 3.715e-19 | 3.324e-17 |
| 53 | CELL CYCLE ARREST | 17 | 154 | 4.098e-19 | 3.598e-17 |
| 54 | SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR | 16 | 127 | 5.551e-19 | 4.783e-17 |
| 55 | REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY | 24 | 470 | 8.312e-19 | 7.032e-17 |
| 56 | CELLULAR RESPONSE TO STRESS | 38 | 1565 | 9.286e-19 | 7.716e-17 |
| 57 | REGULATION OF CHROMOSOME ORGANIZATION | 20 | 278 | 1.244e-18 | 1.016e-16 |
| 58 | REGULATION OF CELL PROLIFERATION | 37 | 1496 | 1.751e-18 | 1.405e-16 |
| 59 | REGULATION OF CHROMOSOME SEGREGATION | 14 | 85 | 1.974e-18 | 1.557e-16 |
| 60 | POSITIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS | 17 | 192 | 1.833e-17 | 1.421e-15 |
| 61 | ANAPHASE PROMOTING COMPLEX DEPENDENT CATABOLIC PROCESS | 13 | 77 | 2.474e-17 | 1.887e-15 |
| 62 | REGULATION OF LIGASE ACTIVITY | 15 | 130 | 2.929e-17 | 2.198e-15 |
| 63 | REGULATION OF PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS | 14 | 103 | 3.348e-17 | 2.472e-15 |
| 64 | PROTEIN UBIQUITINATION INVOLVED IN UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS | 15 | 134 | 4.668e-17 | 3.393e-15 |
| 65 | DNA REPLICATION INITIATION | 10 | 29 | 4.778e-17 | 3.42e-15 |
| 66 | POSITIVE REGULATION OF LIGASE ACTIVITY | 14 | 110 | 8.711e-17 | 6.142e-15 |
| 67 | REGULATION OF CATABOLIC PROCESS | 26 | 731 | 1.618e-16 | 1.124e-14 |
| 68 | POSITIVE REGULATION OF CATALYTIC ACTIVITY | 35 | 1518 | 1.853e-16 | 1.268e-14 |
| 69 | POSITIVE REGULATION OF PROTEIN CATABOLIC PROCESS | 18 | 263 | 1.9e-16 | 1.281e-14 |
| 70 | POSITIVE REGULATION OF CELL DEATH | 24 | 605 | 2.594e-16 | 1.724e-14 |
| 71 | PROTEASOMAL PROTEIN CATABOLIC PROCESS | 18 | 271 | 3.224e-16 | 2.113e-14 |
| 72 | NEGATIVE REGULATION OF CATALYTIC ACTIVITY | 27 | 829 | 3.325e-16 | 2.146e-14 |
| 73 | NUCLEAR CHROMOSOME SEGREGATION | 17 | 228 | 3.367e-16 | 2.146e-14 |
| 74 | CHROMOSOME SEGREGATION | 18 | 272 | 3.441e-16 | 2.163e-14 |
| 75 | POSITIVE REGULATION OF MITOTIC CELL CYCLE | 14 | 123 | 4.363e-16 | 2.707e-14 |
| 76 | POSITIVE REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL | 16 | 196 | 6.406e-16 | 3.922e-14 |
| 77 | RESPONSE TO ABIOTIC STIMULUS | 29 | 1024 | 8.032e-16 | 4.854e-14 |
| 78 | POSITIVE REGULATION OF GENE EXPRESSION | 36 | 1733 | 1.544e-15 | 9.211e-14 |
| 79 | DNA REPLICATION | 16 | 208 | 1.648e-15 | 9.704e-14 |
| 80 | SISTER CHROMATID SEGREGATION | 15 | 176 | 2.922e-15 | 1.699e-13 |
| 81 | NEGATIVE REGULATION OF MOLECULAR FUNCTION | 29 | 1079 | 3.135e-15 | 1.801e-13 |
| 82 | RESPONSE TO OXYGEN LEVELS | 18 | 311 | 3.596e-15 | 2.041e-13 |
| 83 | NEGATIVE REGULATION OF CHROMOSOME SEGREGATION | 9 | 28 | 3.968e-15 | 2.224e-13 |
| 84 | REGULATION OF CELL DEATH | 33 | 1472 | 4.156e-15 | 2.302e-13 |
| 85 | POSITIVE REGULATION OF MOLECULAR FUNCTION | 36 | 1791 | 4.302e-15 | 2.355e-13 |
| 86 | POSITIVE REGULATION OF BIOSYNTHETIC PROCESS | 36 | 1805 | 5.477e-15 | 2.963e-13 |
| 87 | PROTEIN PHOSPHORYLATION | 27 | 944 | 8.033e-15 | 4.296e-13 |
| 88 | POSITIVE REGULATION OF CELL CYCLE PHASE TRANSITION | 11 | 68 | 1.303e-14 | 6.887e-13 |
| 89 | NEGATIVE REGULATION OF MITOTIC NUCLEAR DIVISION | 9 | 34 | 2.946e-14 | 1.54e-12 |
| 90 | CELL DEATH | 27 | 1001 | 3.315e-14 | 1.714e-12 |
| 91 | POSITIVE REGULATION OF FIBROBLAST PROLIFERATION | 10 | 53 | 4.252e-14 | 2.174e-12 |
| 92 | POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION | 18 | 360 | 4.509e-14 | 2.281e-12 |
| 93 | PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL | 25 | 873 | 9.677e-14 | 4.842e-12 |
| 94 | REGULATION OF FIBROBLAST PROLIFERATION | 11 | 81 | 9.814e-14 | 4.858e-12 |
| 95 | SISTER CHROMATID COHESION | 12 | 111 | 1.163e-13 | 5.698e-12 |
| 96 | PROTEIN CATABOLIC PROCESS | 21 | 579 | 1.458e-13 | 7.065e-12 |
| 97 | REGULATION OF PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS | 13 | 148 | 1.581e-13 | 7.584e-12 |
| 98 | NEGATIVE REGULATION OF CELL DIVISION | 10 | 60 | 1.602e-13 | 7.605e-12 |
| 99 | REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL | 16 | 280 | 1.725e-13 | 8.106e-12 |
| 100 | POSITIVE REGULATION OF CELL PROLIFERATION | 24 | 814 | 1.79e-13 | 8.33e-12 |
| 101 | INTRACELLULAR SIGNAL TRANSDUCTION | 32 | 1572 | 1.809e-13 | 8.332e-12 |
| 102 | POSITIVE REGULATION OF CATABOLIC PROCESS | 18 | 395 | 2.199e-13 | 1.003e-11 |
| 103 | NEGATIVE REGULATION OF NUCLEAR DIVISION | 9 | 46 | 5.917e-13 | 2.673e-11 |
| 104 | REGULATION OF CELLULAR PROTEIN LOCALIZATION | 20 | 552 | 6.165e-13 | 2.758e-11 |
| 105 | DNA DEPENDENT DNA REPLICATION | 11 | 99 | 9.541e-13 | 4.228e-11 |
| 106 | NEGATIVE REGULATION OF CELL PROLIFERATION | 21 | 643 | 1.094e-12 | 4.804e-11 |
| 107 | REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS | 13 | 181 | 2.121e-12 | 9.222e-11 |
| 108 | POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER | 25 | 1004 | 2.149e-12 | 9.26e-11 |
| 109 | REGULATION OF DNA METABOLIC PROCESS | 16 | 340 | 3.353e-12 | 1.431e-10 |
| 110 | POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY | 8 | 36 | 4.001e-12 | 1.692e-10 |
| 111 | PHOSPHORYLATION | 27 | 1228 | 4.173e-12 | 1.749e-10 |
| 112 | POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS | 25 | 1036 | 4.267e-12 | 1.757e-10 |
| 113 | POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS | 25 | 1036 | 4.267e-12 | 1.757e-10 |
| 114 | NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS | 19 | 541 | 4.357e-12 | 1.763e-10 |
| 115 | NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS | 19 | 541 | 4.357e-12 | 1.763e-10 |
| 116 | RESPONSE TO RADIATION | 17 | 413 | 5.568e-12 | 2.233e-10 |
| 117 | DNA REPAIR | 18 | 480 | 5.815e-12 | 2.313e-10 |
| 118 | POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION | 26 | 1152 | 6.458e-12 | 2.525e-10 |
| 119 | REGULATION OF CELL CYCLE G2 M PHASE TRANSITION | 9 | 59 | 6.428e-12 | 2.525e-10 |
| 120 | REPLICATIVE SENESCENCE | 6 | 12 | 7.255e-12 | 2.813e-10 |
| 121 | POSITIVE REGULATION OF ORGANELLE ORGANIZATION | 19 | 573 | 1.18e-11 | 4.538e-10 |
| 122 | RESPONSE TO UV | 11 | 126 | 1.391e-11 | 5.304e-10 |
| 123 | SPINDLE CHECKPOINT | 7 | 25 | 1.552e-11 | 5.872e-10 |
| 124 | CELLULAR RESPONSE TO UV | 9 | 66 | 1.844e-11 | 6.921e-10 |
| 125 | REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY | 8 | 43 | 1.868e-11 | 6.952e-10 |
| 126 | REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER | 31 | 1784 | 3.028e-11 | 1.118e-09 |
| 127 | CELLULAR RESPONSE TO RADIATION | 11 | 137 | 3.478e-11 | 1.274e-09 |
| 128 | NEGATIVE REGULATION OF PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL | 11 | 139 | 4.073e-11 | 1.481e-09 |
| 129 | REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY | 7 | 29 | 4.965e-11 | 1.777e-09 |
| 130 | POSITIVE REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY | 7 | 29 | 4.965e-11 | 1.777e-09 |
| 131 | POSITIVE REGULATION OF STEM CELL DIFFERENTIATION | 8 | 50 | 6.736e-11 | 2.392e-09 |
| 132 | NEGATIVE REGULATION OF PROTEIN CATABOLIC PROCESS | 10 | 109 | 7.541e-11 | 2.658e-09 |
| 133 | NEGATIVE REGULATION OF PHOSPHORYLATION | 16 | 422 | 8.475e-11 | 2.965e-09 |
| 134 | NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS | 28 | 1517 | 9.388e-11 | 3.26e-09 |
| 135 | RESPONSE TO DRUG | 16 | 431 | 1.157e-10 | 3.987e-09 |
| 136 | MACROMOLECULE CATABOLIC PROCESS | 22 | 926 | 1.45e-10 | 4.959e-09 |
| 137 | NEGATIVE REGULATION OF DNA REPLICATION | 8 | 55 | 1.499e-10 | 5.092e-09 |
| 138 | PEPTIDYL AMINO ACID MODIFICATION | 21 | 841 | 1.662e-10 | 5.604e-09 |
| 139 | POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION | 7 | 34 | 1.68e-10 | 5.623e-09 |
| 140 | REGULATION OF DNA REPLICATION | 11 | 161 | 1.999e-10 | 6.645e-09 |
| 141 | NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION | 19 | 684 | 2.415e-10 | 7.97e-09 |
| 142 | POSITIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY | 7 | 36 | 2.587e-10 | 8.478e-09 |
| 143 | CELLULAR RESPONSE TO LIGHT STIMULUS | 9 | 91 | 3.556e-10 | 1.149e-08 |
| 144 | MITOTIC SISTER CHROMATID SEGREGATION | 9 | 91 | 3.556e-10 | 1.149e-08 |
| 145 | RESPONSE TO LIPID | 21 | 888 | 4.474e-10 | 1.436e-08 |
| 146 | PROTEIN UBIQUITINATION | 18 | 629 | 4.78e-10 | 1.524e-08 |
| 147 | NEGATIVE REGULATION OF CELLULAR PROTEIN CATABOLIC PROCESS | 8 | 64 | 5.27e-10 | 1.668e-08 |
| 148 | NEGATIVE REGULATION OF CHROMOSOME ORGANIZATION | 9 | 96 | 5.774e-10 | 1.815e-08 |
| 149 | APOPTOTIC SIGNALING PATHWAY | 13 | 289 | 7.371e-10 | 2.302e-08 |
| 150 | RESPONSE TO ORGANIC CYCLIC COMPOUND | 21 | 917 | 7.994e-10 | 2.48e-08 |
| 151 | MEIOTIC CELL CYCLE | 11 | 186 | 9.347e-10 | 2.88e-08 |
| 152 | REGULATION OF MEMBRANE PERMEABILITY | 8 | 70 | 1.099e-09 | 3.364e-08 |
| 153 | POSITIVE REGULATION OF CHROMOSOME SEGREGATION | 6 | 25 | 1.325e-09 | 4.031e-08 |
| 154 | CELL PROLIFERATION | 18 | 672 | 1.368e-09 | 4.134e-08 |
| 155 | POSITIVE REGULATION OF INTRACELLULAR TRANSPORT | 14 | 370 | 1.47e-09 | 4.414e-08 |
| 156 | POSITIVE REGULATION OF CHROMOSOME ORGANIZATION | 10 | 150 | 1.774e-09 | 5.293e-08 |
| 157 | PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS | 30 | 1977 | 1.879e-09 | 5.569e-08 |
| 158 | INTRINSIC APOPTOTIC SIGNALING PATHWAY | 10 | 152 | 2.019e-09 | 5.946e-08 |
| 159 | REGULATION OF CELLULAR RESPONSE TO STRESS | 18 | 691 | 2.124e-09 | 6.186e-08 |
| 160 | NEGATIVE REGULATION OF DNA METABOLIC PROCESS | 9 | 111 | 2.127e-09 | 6.186e-08 |
| 161 | REGULATION OF TRANSCRIPTION INVOLVED IN G1 S TRANSITION OF MITOTIC CELL CYCLE | 6 | 27 | 2.199e-09 | 6.355e-08 |
| 162 | NEGATIVE REGULATION OF ORGANELLE ORGANIZATION | 14 | 387 | 2.619e-09 | 7.522e-08 |
| 163 | PROTEIN SUMOYLATION | 9 | 115 | 2.916e-09 | 8.325e-08 |
| 164 | CELLULAR RESPONSE TO ABIOTIC STIMULUS | 12 | 263 | 2.971e-09 | 8.431e-08 |
| 165 | CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND | 15 | 465 | 3.188e-09 | 8.991e-08 |
| 166 | NEGATIVE REGULATION OF PROTEOLYSIS | 13 | 329 | 3.545e-09 | 9.937e-08 |
| 167 | POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION | 10 | 162 | 3.748e-09 | 1.044e-07 |
| 168 | PROTEOLYSIS | 23 | 1208 | 3.777e-09 | 1.046e-07 |
| 169 | POSITIVE REGULATION OF RESPONSE TO STIMULUS | 29 | 1929 | 4.787e-09 | 1.318e-07 |
| 170 | NEGATIVE REGULATION OF CELL GROWTH | 10 | 170 | 5.972e-09 | 1.634e-07 |
| 171 | POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY | 10 | 171 | 6.319e-09 | 1.719e-07 |
| 172 | RESPONSE TO STEROID HORMONE | 15 | 497 | 7.808e-09 | 2.112e-07 |
| 173 | REGULATION OF PROTEIN LOCALIZATION | 20 | 950 | 9.076e-09 | 2.441e-07 |
| 174 | POSITIVE REGULATION OF CELL DIVISION | 9 | 132 | 9.873e-09 | 2.64e-07 |
| 175 | MITOCHONDRIAL MEMBRANE ORGANIZATION | 8 | 92 | 9.98e-09 | 2.653e-07 |
| 176 | RHYTHMIC PROCESS | 12 | 298 | 1.204e-08 | 3.183e-07 |
| 177 | POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION | 15 | 514 | 1.224e-08 | 3.216e-07 |
| 178 | NEGATIVE REGULATION OF KINASE ACTIVITY | 11 | 250 | 2.058e-08 | 5.381e-07 |
| 179 | REGULATION OF INTRACELLULAR TRANSPORT | 16 | 621 | 2.177e-08 | 5.659e-07 |
| 180 | REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION | 7 | 67 | 2.401e-08 | 6.208e-07 |
| 181 | DIGESTIVE SYSTEM DEVELOPMENT | 9 | 148 | 2.685e-08 | 6.902e-07 |
| 182 | REGULATION OF CELL GROWTH | 13 | 391 | 2.762e-08 | 7.061e-07 |
| 183 | NEGATIVE REGULATION OF CATABOLIC PROCESS | 10 | 203 | 3.253e-08 | 8.27e-07 |
| 184 | RESPONSE TO GROWTH FACTOR | 14 | 475 | 3.484e-08 | 8.81e-07 |
| 185 | INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE | 7 | 71 | 3.618e-08 | 9.1e-07 |
| 186 | POSITIVE REGULATION OF KINASE ACTIVITY | 14 | 482 | 4.178e-08 | 1.045e-06 |
| 187 | NEGATIVE REGULATION OF GENE EXPRESSION | 24 | 1493 | 4.269e-08 | 1.062e-06 |
| 188 | REGULATION OF STEM CELL DIFFERENTIATION | 8 | 113 | 5.072e-08 | 1.255e-06 |
| 189 | INTERSPECIES INTERACTION BETWEEN ORGANISMS | 16 | 662 | 5.275e-08 | 1.292e-06 |
| 190 | SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM | 16 | 662 | 5.275e-08 | 1.292e-06 |
| 191 | REGULATION OF SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR | 9 | 162 | 5.874e-08 | 1.431e-06 |
| 192 | REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS | 10 | 218 | 6.372e-08 | 1.544e-06 |
| 193 | RESPONSE TO LIGHT STIMULUS | 11 | 280 | 6.558e-08 | 1.581e-06 |
| 194 | POSITIVE REGULATION OF CELL COMMUNICATION | 24 | 1532 | 6.952e-08 | 1.659e-06 |
| 195 | REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT | 10 | 220 | 6.943e-08 | 1.659e-06 |
| 196 | NEGATIVE REGULATION OF CELL DEATH | 18 | 872 | 7.621e-08 | 1.809e-06 |
| 197 | POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT | 8 | 121 | 8.655e-08 | 2.044e-06 |
| 198 | POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY | 11 | 289 | 9.037e-08 | 2.124e-06 |
| 199 | DNA GEOMETRIC CHANGE | 7 | 81 | 9.115e-08 | 2.131e-06 |
| 200 | CELLULAR CATABOLIC PROCESS | 22 | 1322 | 9.811e-08 | 2.282e-06 |
| 201 | RESPONSE TO ALCOHOL | 12 | 362 | 1.019e-07 | 2.36e-06 |
| 202 | RESPONSE TO ENDOGENOUS STIMULUS | 23 | 1450 | 1.118e-07 | 2.575e-06 |
| 203 | NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY | 8 | 126 | 1.186e-07 | 2.718e-06 |
| 204 | CELLULAR RESPONSE TO ENDOGENOUS STIMULUS | 19 | 1008 | 1.298e-07 | 2.961e-06 |
| 205 | REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION | 8 | 128 | 1.34e-07 | 3.026e-06 |
| 206 | NEGATIVE REGULATION OF GROWTH | 10 | 236 | 1.338e-07 | 3.026e-06 |
| 207 | PROTEIN K11 LINKED UBIQUITINATION | 5 | 27 | 1.375e-07 | 3.091e-06 |
| 208 | POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS | 8 | 129 | 1.423e-07 | 3.183e-06 |
| 209 | RESPONSE TO KETONE | 9 | 182 | 1.594e-07 | 3.548e-06 |
| 210 | REGULATION OF MICROTUBULE BASED PROCESS | 10 | 243 | 1.756e-07 | 3.873e-06 |
| 211 | PROTEIN POLYUBIQUITINATION | 10 | 243 | 1.756e-07 | 3.873e-06 |
| 212 | REGULATION OF GROWTH | 15 | 633 | 1.866e-07 | 4.095e-06 |
| 213 | PEPTIDYL LYSINE MODIFICATION | 11 | 312 | 1.953e-07 | 4.266e-06 |
| 214 | SMAD PROTEIN SIGNAL TRANSDUCTION | 6 | 56 | 2.167e-07 | 4.713e-06 |
| 215 | NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER | 16 | 740 | 2.401e-07 | 5.196e-06 |
| 216 | CELLULAR RESPONSE TO OXYGEN LEVELS | 8 | 143 | 3.148e-07 | 6.781e-06 |
| 217 | REPRODUCTION | 21 | 1297 | 3.225e-07 | 6.916e-06 |
| 218 | CHROMATIN ORGANIZATION | 15 | 663 | 3.371e-07 | 7.196e-06 |
| 219 | RESPONSE TO IONIZING RADIATION | 8 | 145 | 3.501e-07 | 7.406e-06 |
| 220 | REGULATION OF RESPONSE TO DNA DAMAGE STIMULUS | 8 | 145 | 3.501e-07 | 7.406e-06 |
| 221 | POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY | 7 | 100 | 3.909e-07 | 8.231e-06 |
| 222 | G2 DNA DAMAGE CHECKPOINT | 5 | 33 | 3.956e-07 | 8.291e-06 |
| 223 | POSITIVE REGULATION OF MITOTIC SISTER CHROMATID SEPARATION | 4 | 14 | 4.051e-07 | 8.378e-06 |
| 224 | POSITIVE REGULATION OF MITOTIC METAPHASE ANAPHASE TRANSITION | 4 | 14 | 4.051e-07 | 8.378e-06 |
| 225 | POSITIVE REGULATION OF METAPHASE ANAPHASE TRANSITION OF CELL CYCLE | 4 | 14 | 4.051e-07 | 8.378e-06 |
| 226 | REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION | 11 | 337 | 4.208e-07 | 8.664e-06 |
| 227 | REGULATION OF CYTOSKELETON ORGANIZATION | 13 | 502 | 4.925e-07 | 1.009e-05 |
| 228 | MEIOTIC CELL CYCLE PROCESS | 8 | 152 | 5.02e-07 | 1.024e-05 |
| 229 | DNA CONFORMATION CHANGE | 10 | 273 | 5.133e-07 | 1.043e-05 |
| 230 | RESPONSE TO HORMONE | 17 | 893 | 5.761e-07 | 1.165e-05 |
| 231 | REGULATION OF RESPONSE TO STRESS | 22 | 1468 | 5.958e-07 | 1.2e-05 |
| 232 | NEGATIVE REGULATION OF CELLULAR CATABOLIC PROCESS | 8 | 156 | 6.117e-07 | 1.227e-05 |
| 233 | CELL AGING | 6 | 67 | 6.397e-07 | 1.277e-05 |
| 234 | REGULATION OF BINDING | 10 | 283 | 7.128e-07 | 1.417e-05 |
| 235 | NEGATIVE REGULATION OF DNA DEPENDENT DNA REPLICATION | 4 | 16 | 7.314e-07 | 1.436e-05 |
| 236 | REGULATION OF MITOCHONDRION ORGANIZATION | 9 | 218 | 7.309e-07 | 1.436e-05 |
| 237 | RESPONSE TO ESTROGEN | 9 | 218 | 7.309e-07 | 1.436e-05 |
| 238 | MESENCHYME MORPHOGENESIS | 5 | 38 | 8.216e-07 | 1.606e-05 |
| 239 | REGULATION OF APOPTOTIC SIGNALING PATHWAY | 11 | 363 | 8.751e-07 | 1.704e-05 |
| 240 | CATABOLIC PROCESS | 24 | 1773 | 1.02e-06 | 1.977e-05 |
| 241 | POSITIVE REGULATION OF MITOCHONDRION ORGANIZATION | 8 | 167 | 1.025e-06 | 1.979e-05 |
| 242 | CHROMATIN MODIFICATION | 13 | 539 | 1.093e-06 | 2.101e-05 |
| 243 | REGULATION OF CELLULAR LOCALIZATION | 20 | 1277 | 1.097e-06 | 2.101e-05 |
| 244 | REGULATION OF DNA DEPENDENT DNA REPLICATION | 5 | 41 | 1.213e-06 | 2.314e-05 |
| 245 | MITOCHONDRIAL TRANSPORT | 8 | 177 | 1.588e-06 | 3.015e-05 |
| 246 | REGULATION OF MICROTUBULE POLYMERIZATION OR DEPOLYMERIZATION | 8 | 178 | 1.656e-06 | 3.133e-05 |
| 247 | NEGATIVE REGULATION OF CELL CYCLE ARREST | 4 | 20 | 1.92e-06 | 3.617e-05 |
| 248 | CELLULAR RESPONSE TO ORGANIC SUBSTANCE | 24 | 1848 | 2.129e-06 | 3.994e-05 |
| 249 | ORGAN REGENERATION | 6 | 83 | 2.281e-06 | 4.262e-05 |
| 250 | POSITIVE REGULATION OF CHROMATIN MODIFICATION | 6 | 85 | 2.624e-06 | 4.883e-05 |
| 251 | POSITIVE REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION | 5 | 48 | 2.703e-06 | 5.011e-05 |
| 252 | MEIOSIS I | 6 | 88 | 3.215e-06 | 5.937e-05 |
| 253 | RESPONSE TO GAMMA RADIATION | 5 | 50 | 3.32e-06 | 6.107e-05 |
| 254 | POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS | 4 | 23 | 3.472e-06 | 6.335e-05 |
| 255 | POSITIVE REGULATION OF COLLAGEN METABOLIC PROCESS | 4 | 23 | 3.472e-06 | 6.335e-05 |
| 256 | CELLULAR RESPONSE TO EXTERNAL STIMULUS | 9 | 264 | 3.549e-06 | 6.426e-05 |
| 257 | AGING | 9 | 264 | 3.549e-06 | 6.426e-05 |
| 258 | RESPONSE TO OXYGEN CONTAINING COMPOUND | 20 | 1381 | 3.648e-06 | 6.579e-05 |
| 259 | POSITIVE REGULATION OF MITOTIC NUCLEAR DIVISION | 5 | 51 | 3.668e-06 | 6.59e-05 |
| 260 | POSITIVE REGULATION OF DEVELOPMENTAL PROCESS | 18 | 1142 | 3.819e-06 | 6.834e-05 |
| 261 | INTRINSIC APOPTOTIC SIGNALING PATHWAY BY P53 CLASS MEDIATOR | 5 | 53 | 4.449e-06 | 7.931e-05 |
| 262 | RESPONSE TO TRANSFORMING GROWTH FACTOR BETA | 7 | 144 | 4.555e-06 | 8.09e-05 |
| 263 | TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY | 6 | 95 | 5.025e-06 | 8.89e-05 |
| 264 | REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY | 8 | 207 | 5.085e-06 | 8.962e-05 |
| 265 | TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER | 14 | 724 | 5.403e-06 | 9.486e-05 |
| 266 | PEPTIDYL SERINE MODIFICATION | 7 | 148 | 5.459e-06 | 9.549e-05 |
| 267 | EPITHELIUM DEVELOPMENT | 16 | 945 | 5.85e-06 | 0.0001019 |
| 268 | POSITIVE REGULATION OF PROTEASOMAL PROTEIN CATABOLIC PROCESS | 6 | 98 | 6.019e-06 | 0.0001045 |
| 269 | REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY | 8 | 213 | 6.273e-06 | 0.0001085 |
| 270 | REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY | 6 | 99 | 6.384e-06 | 0.0001094 |
| 271 | ORGAN MORPHOGENESIS | 15 | 841 | 6.394e-06 | 0.0001094 |
| 272 | REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS | 6 | 99 | 6.384e-06 | 0.0001094 |
| 273 | REGULATION OF CHROMATIN ORGANIZATION | 7 | 152 | 6.507e-06 | 0.0001109 |
| 274 | REGULATION OF EPITHELIAL CELL PROLIFERATION | 9 | 285 | 6.6e-06 | 0.0001121 |
| 275 | CELLULAR RESPONSE TO STEROID HORMONE STIMULUS | 8 | 218 | 7.436e-06 | 0.0001258 |
| 276 | CELLULAR RESPONSE TO LIPID | 11 | 457 | 7.999e-06 | 0.0001348 |
| 277 | REGULATION OF PROTEIN STABILITY | 8 | 221 | 8.217e-06 | 0.000138 |
| 278 | REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION | 5 | 60 | 8.255e-06 | 0.0001382 |
| 279 | REGULATION OF CELL MORPHOGENESIS | 12 | 552 | 8.444e-06 | 0.0001408 |
| 280 | NEGATIVE REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE | 4 | 29 | 9.118e-06 | 0.000151 |
| 281 | REGULATION OF HEART MORPHOGENESIS | 4 | 29 | 9.118e-06 | 0.000151 |
| 282 | REGENERATION | 7 | 161 | 9.489e-06 | 0.0001566 |
| 283 | SOMITOGENESIS | 5 | 62 | 9.71e-06 | 0.0001591 |
| 284 | POSITIVE REGULATION OF NUCLEAR DIVISION | 5 | 62 | 9.71e-06 | 0.0001591 |
| 285 | REGULATION OF INTRACELLULAR PROTEIN TRANSPORT | 10 | 381 | 1.007e-05 | 0.0001643 |
| 286 | REGULATION OF PROTEIN ACETYLATION | 5 | 64 | 1.136e-05 | 0.0001848 |
| 287 | REGULATION OF CELL DIFFERENTIATION | 20 | 1492 | 1.156e-05 | 0.0001875 |
| 288 | NEGATIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY | 4 | 32 | 1.366e-05 | 0.0002201 |
| 289 | NUCLEOTIDE EXCISION REPAIR | 6 | 113 | 1.367e-05 | 0.0002201 |
| 290 | GLAND DEVELOPMENT | 10 | 395 | 1.376e-05 | 0.0002208 |
| 291 | REGULATION OF DNA TEMPLATED TRANSCRIPTION IN RESPONSE TO STRESS | 5 | 67 | 1.423e-05 | 0.0002276 |
| 292 | NOTCH SIGNALING PATHWAY | 6 | 114 | 1.438e-05 | 0.0002291 |
| 293 | TISSUE DEVELOPMENT | 20 | 1518 | 1.49e-05 | 0.0002366 |
| 294 | NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION | 6 | 115 | 1.511e-05 | 0.0002387 |
| 295 | ACTIVATION OF MAPKKK ACTIVITY | 3 | 11 | 1.513e-05 | 0.0002387 |
| 296 | REGULATION OF PROTEIN EXPORT FROM NUCLEUS | 4 | 33 | 1.549e-05 | 0.0002435 |
| 297 | PROTEIN COMPLEX SUBUNIT ORGANIZATION | 20 | 1527 | 1.624e-05 | 0.0002544 |
| 298 | MITOTIC SPINDLE ORGANIZATION | 5 | 69 | 1.644e-05 | 0.0002567 |
| 299 | MACROMOLECULAR COMPLEX ASSEMBLY | 19 | 1398 | 1.65e-05 | 0.0002568 |
| 300 | NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS | 14 | 801 | 1.69e-05 | 0.0002621 |
| 301 | PROTEIN DESTABILIZATION | 4 | 34 | 1.749e-05 | 0.0002704 |
| 302 | RESPONSE TO MINERALOCORTICOID | 4 | 35 | 1.968e-05 | 0.0003022 |
| 303 | RESPONSE TO IRON ION | 4 | 35 | 1.968e-05 | 0.0003022 |
| 304 | REGULATION OF MACROPHAGE CYTOKINE PRODUCTION | 3 | 12 | 2.011e-05 | 0.0003058 |
| 305 | POSITIVE REGULATION OF SMAD PROTEIN IMPORT INTO NUCLEUS | 3 | 12 | 2.011e-05 | 0.0003058 |
| 306 | MITOTIC SISTER CHROMATID COHESION | 3 | 12 | 2.011e-05 | 0.0003058 |
| 307 | TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR | 5 | 73 | 2.166e-05 | 0.0003283 |
| 308 | REGULATION OF PROTEIN IMPORT | 7 | 183 | 2.178e-05 | 0.000329 |
| 309 | NEGATIVE REGULATION OF CELL DIFFERENTIATION | 12 | 609 | 2.243e-05 | 0.0003378 |
| 310 | POSITIVE REGULATION OF TRANSPORT | 15 | 936 | 2.266e-05 | 0.0003402 |
| 311 | POSITIVE REGULATION OF DNA METABOLIC PROCESS | 7 | 185 | 2.336e-05 | 0.0003495 |
| 312 | POSITIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT | 8 | 258 | 2.515e-05 | 0.0003751 |
| 313 | MITOTIC CELL CYCLE ARREST | 3 | 13 | 2.606e-05 | 0.0003873 |
| 314 | REGULATION OF CELLULAR RESPONSE TO HEAT | 5 | 76 | 2.635e-05 | 0.0003905 |
| 315 | REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS | 4 | 38 | 2.746e-05 | 0.0004056 |
| 316 | MESENCHYME DEVELOPMENT | 7 | 190 | 2.772e-05 | 0.0004081 |
| 317 | SOMITE DEVELOPMENT | 5 | 78 | 2.99e-05 | 0.0004388 |
| 318 | MICROTUBULE CYTOSKELETON ORGANIZATION | 9 | 348 | 3.219e-05 | 0.000471 |
| 319 | POSITIVE REGULATION OF P38MAPK CASCADE | 3 | 14 | 3.305e-05 | 0.0004821 |
| 320 | CIRCADIAN RHYTHM | 6 | 137 | 4.072e-05 | 0.0005902 |
| 321 | NEGATIVE REGULATION OF RESPONSE TO STIMULUS | 18 | 1360 | 4.069e-05 | 0.0005902 |
| 322 | ACTIVATION OF ANAPHASE PROMOTING COMPLEX ACTIVITY | 3 | 15 | 4.118e-05 | 0.000595 |
| 323 | BETA CATENIN TCF COMPLEX ASSEMBLY | 4 | 43 | 4.51e-05 | 0.0006497 |
| 324 | TUBE DEVELOPMENT | 11 | 552 | 4.567e-05 | 0.0006559 |
| 325 | POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT | 8 | 282 | 4.729e-05 | 0.000677 |
| 326 | REGULATION OF SMAD PROTEIN IMPORT INTO NUCLEUS | 3 | 16 | 5.051e-05 | 0.0007187 |
| 327 | CELLULAR RESPONSE TO ANTIBIOTIC | 3 | 16 | 5.051e-05 | 0.0007187 |
| 328 | PROTEIN LOCALIZATION TO CHROMOSOME | 4 | 45 | 5.407e-05 | 0.0007671 |
| 329 | HEART DEVELOPMENT | 10 | 466 | 5.604e-05 | 0.0007926 |
| 330 | SEGMENTATION | 5 | 89 | 5.649e-05 | 0.0007965 |
| 331 | RESPONSE TO ESTRADIOL | 6 | 146 | 5.81e-05 | 0.0008168 |
| 332 | MESONEPHROS DEVELOPMENT | 5 | 90 | 5.96e-05 | 0.0008353 |
| 333 | POSITIVE REGULATION OF EXTRACELLULAR MATRIX ORGANIZATION | 3 | 17 | 6.113e-05 | 0.0008516 |
| 334 | REGULATION OF SISTER CHROMATID COHESION | 3 | 17 | 6.113e-05 | 0.0008516 |
| 335 | POSITIVE REGULATION OF CELL DEVELOPMENT | 10 | 472 | 6.235e-05 | 0.000866 |
| 336 | RESPONSE TO ANTIBIOTIC | 4 | 47 | 6.428e-05 | 0.0008874 |
| 337 | REGULATION OF PROTEIN COMPLEX DISASSEMBLY | 7 | 217 | 6.446e-05 | 0.0008874 |
| 338 | POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS | 4 | 47 | 6.428e-05 | 0.0008874 |
| 339 | CHROMATIN REMODELING | 6 | 150 | 6.753e-05 | 0.0009268 |
| 340 | REGULATION OF LIPID KINASE ACTIVITY | 4 | 48 | 6.988e-05 | 0.0009535 |
| 341 | HOMOLOGOUS CHROMOSOME SEGREGATION | 4 | 48 | 6.988e-05 | 0.0009535 |
| 342 | RESPONSE TO INORGANIC SUBSTANCE | 10 | 479 | 7.046e-05 | 0.0009587 |
| 343 | POSITIVE REGULATION OF CELL CYCLE G2 M PHASE TRANSITION | 3 | 18 | 7.311e-05 | 0.000986 |
| 344 | REGULATION OF CYTOPLASMIC TRANSPORT | 10 | 481 | 7.294e-05 | 0.000986 |
| 345 | REGULATION OF UBIQUITIN PROTEIN LIGASE ACTIVITY | 3 | 18 | 7.311e-05 | 0.000986 |
| 346 | REGULATION OF DNA BIOSYNTHETIC PROCESS | 5 | 94 | 7.337e-05 | 0.0009866 |
| 347 | REGULATION OF PEPTIDASE ACTIVITY | 9 | 392 | 8.066e-05 | 0.001082 |
| 348 | RESPONSE TO PROGESTERONE | 4 | 50 | 8.213e-05 | 0.001098 |
| 349 | REGULATION OF PROTEIN TARGETING | 8 | 307 | 8.569e-05 | 0.001142 |
| 350 | POSITIVE REGULATION OF PROTEIN EXPORT FROM NUCLEUS | 3 | 19 | 8.653e-05 | 0.00115 |
| 351 | HEMATOPOIETIC PROGENITOR CELL DIFFERENTIATION | 5 | 98 | 8.947e-05 | 0.001183 |
| 352 | RESPONSE TO VITAMIN | 5 | 98 | 8.947e-05 | 0.001183 |
| 353 | CELLULAR RESPONSE TO IONIZING RADIATION | 4 | 52 | 9.587e-05 | 0.001264 |
| 354 | POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS | 9 | 406 | 0.0001053 | 0.001384 |
| 355 | GROWTH | 9 | 410 | 0.0001134 | 0.001486 |
| 356 | POSITIVE REGULATION OF PROTEIN IMPORT | 5 | 104 | 0.0001186 | 0.001545 |
| 357 | CELLULAR RESPONSE TO REACTIVE OXYGEN SPECIES | 5 | 104 | 0.0001186 | 0.001545 |
| 358 | CRANIAL SKELETAL SYSTEM DEVELOPMENT | 4 | 55 | 0.0001195 | 0.001553 |
| 359 | RESPONSE TO TOXIC SUBSTANCE | 7 | 241 | 0.0001241 | 0.001609 |
| 360 | EPITHELIAL TO MESENCHYMAL TRANSITION | 4 | 56 | 0.0001282 | 0.001658 |
| 361 | NEGATIVE REGULATION OF PROTEIN COMPLEX DISASSEMBLY | 6 | 170 | 0.0001346 | 0.001735 |
| 362 | NEGATIVE REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE | 3 | 22 | 0.0001362 | 0.001745 |
| 363 | ENDOCARDIAL CUSHION MORPHOGENESIS | 3 | 22 | 0.0001362 | 0.001745 |
| 364 | MICROTUBULE BASED PROCESS | 10 | 522 | 0.0001428 | 0.001825 |
| 365 | CELLULAR MACROMOLECULE LOCALIZATION | 16 | 1234 | 0.0001475 | 0.001881 |
| 366 | RESPONSE TO NITROGEN COMPOUND | 13 | 859 | 0.0001494 | 0.001899 |
| 367 | RESPONSE TO METAL ION | 8 | 333 | 0.0001501 | 0.001903 |
| 368 | RESPONSE TO INCREASED OXYGEN LEVELS | 3 | 23 | 0.0001561 | 0.001962 |
| 369 | SCF DEPENDENT PROTEASOMAL UBIQUITIN DEPENDENT PROTEIN CATABOLIC PROCESS | 3 | 23 | 0.0001561 | 0.001962 |
| 370 | RESPONSE TO HYPEROXIA | 3 | 23 | 0.0001561 | 0.001962 |
| 371 | REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION | 19 | 1656 | 0.0001629 | 0.002043 |
| 372 | POSITIVE REGULATION OF G1 S TRANSITION OF MITOTIC CELL CYCLE | 3 | 24 | 0.0001778 | 0.002223 |
| 373 | EMBRYONIC DIGIT MORPHOGENESIS | 4 | 61 | 0.0001791 | 0.002228 |
| 374 | CELLULAR RESPONSE TO HYDROGEN PEROXIDE | 4 | 61 | 0.0001791 | 0.002228 |
| 375 | REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT | 19 | 1672 | 0.0001845 | 0.00229 |
| 376 | POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS | 17 | 1395 | 0.0001879 | 0.002325 |
| 377 | COVALENT CHROMATIN MODIFICATION | 8 | 345 | 0.0001911 | 0.002358 |
| 378 | PROTEIN COMPLEX BIOGENESIS | 15 | 1132 | 0.0001928 | 0.002367 |
| 379 | PROTEIN COMPLEX ASSEMBLY | 15 | 1132 | 0.0001928 | 0.002367 |
| 380 | RESPONSE TO EXTRACELLULAR STIMULUS | 9 | 441 | 0.0001958 | 0.002397 |
| 381 | CELLULAR RESPONSE TO TOXIC SUBSTANCE | 3 | 25 | 0.0002013 | 0.002433 |
| 382 | REGULATION OF TRANSFORMING GROWTH FACTOR BETA PRODUCTION | 3 | 25 | 0.0002013 | 0.002433 |
| 383 | POSITIVE REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION | 3 | 25 | 0.0002013 | 0.002433 |
| 384 | EPITHELIAL CELL APOPTOTIC PROCESS | 3 | 25 | 0.0002013 | 0.002433 |
| 385 | HISTONE PHOSPHORYLATION | 3 | 25 | 0.0002013 | 0.002433 |
| 386 | MULTICELLULAR ORGANISM REPRODUCTION | 12 | 768 | 0.0002045 | 0.002465 |
| 387 | CELLULAR RESPONSE TO OXIDATIVE STRESS | 6 | 184 | 0.0002069 | 0.002488 |
| 388 | POSITIVE REGULATION OF RESPONSE TO DNA DAMAGE STIMULUS | 4 | 64 | 0.0002157 | 0.002587 |
| 389 | EMBRYO DEVELOPMENT | 13 | 894 | 0.000221 | 0.002643 |
| 390 | CELLULAR RESPONSE TO HORMONE STIMULUS | 10 | 552 | 0.0002241 | 0.002674 |
| 391 | REGULATION OF CELLULAR SENESCENCE | 3 | 26 | 0.0002268 | 0.002686 |
| 392 | RESPONSE TO CORTICOSTERONE | 3 | 26 | 0.0002268 | 0.002686 |
| 393 | REGULATION OF P38MAPK CASCADE | 3 | 26 | 0.0002268 | 0.002686 |
| 394 | MEIOTIC CHROMOSOME SEGREGATION | 4 | 65 | 0.0002291 | 0.002705 |
| 395 | CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS | 6 | 188 | 0.0002324 | 0.002731 |
| 396 | REGULATION OF DENDRITE DEVELOPMENT | 5 | 120 | 0.0002319 | 0.002731 |
| 397 | NEGATIVE REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS | 4 | 66 | 0.000243 | 0.002841 |
| 398 | NEGATIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY | 4 | 66 | 0.000243 | 0.002841 |
| 399 | TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY | 6 | 190 | 0.0002461 | 0.002869 |
| 400 | RESPONSE TO NUTRIENT | 6 | 191 | 0.0002531 | 0.002944 |
| 401 | POSITIVE REGULATION OF NEURON DEATH | 4 | 67 | 0.0002575 | 0.002981 |
| 402 | CELLULAR RESPONSE TO DRUG | 4 | 67 | 0.0002575 | 0.002981 |
| 403 | ANTERIOR POSTERIOR PATTERN SPECIFICATION | 6 | 194 | 0.0002752 | 0.003178 |
| 404 | KIDNEY EPITHELIUM DEVELOPMENT | 5 | 125 | 0.0002803 | 0.003228 |
| 405 | POSITIVE REGULATION OF LEUKOCYTE APOPTOTIC PROCESS | 3 | 28 | 0.0002839 | 0.003246 |
| 406 | REGULATION OF DNA DAMAGE RESPONSE SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR | 3 | 28 | 0.0002839 | 0.003246 |
| 407 | NEGATIVE REGULATION OF DENDRITE DEVELOPMENT | 3 | 28 | 0.0002839 | 0.003246 |
| 408 | REGULATION OF CELL CYCLE CHECKPOINT | 3 | 29 | 0.0003156 | 0.003573 |
| 409 | REGULATION OF EXTRACELLULAR MATRIX ORGANIZATION | 3 | 29 | 0.0003156 | 0.003573 |
| 410 | NUCLEOTIDE EXCISION REPAIR PREINCISION COMPLEX ASSEMBLY | 3 | 29 | 0.0003156 | 0.003573 |
| 411 | POSITIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION | 3 | 29 | 0.0003156 | 0.003573 |
| 412 | NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS | 8 | 372 | 0.0003176 | 0.003587 |
| 413 | INTRACELLULAR STEROID HORMONE RECEPTOR SIGNALING PATHWAY | 4 | 71 | 0.0003219 | 0.003618 |
| 414 | ENDODERM DEVELOPMENT | 4 | 71 | 0.0003219 | 0.003618 |
| 415 | NEGATIVE REGULATION OF CELL COMMUNICATION | 15 | 1192 | 0.0003359 | 0.003767 |
| 416 | IMMUNE SYSTEM DEVELOPMENT | 10 | 582 | 0.0003414 | 0.003819 |
| 417 | INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE BY P53 CLASS MEDIATOR | 3 | 30 | 0.0003495 | 0.003881 |
| 418 | PROTEIN STABILIZATION | 5 | 131 | 0.0003481 | 0.003881 |
| 419 | RESPONSE TO X RAY | 3 | 30 | 0.0003495 | 0.003881 |
| 420 | POSITIVE REGULATION OF CELL DIFFERENTIATION | 12 | 823 | 0.0003837 | 0.004251 |
| 421 | HEAD DEVELOPMENT | 11 | 709 | 0.0004066 | 0.004493 |
| 422 | SALIVARY GLAND DEVELOPMENT | 3 | 32 | 0.0004242 | 0.004655 |
| 423 | ENDOCARDIAL CUSHION DEVELOPMENT | 3 | 32 | 0.0004242 | 0.004655 |
| 424 | REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO HYPOXIA | 3 | 32 | 0.0004242 | 0.004655 |
| 425 | REGULATION OF CELL DEVELOPMENT | 12 | 836 | 0.0004416 | 0.004835 |
| 426 | SENSORY ORGAN DEVELOPMENT | 9 | 493 | 0.0004433 | 0.004842 |
| 427 | EPITHELIAL CELL DIFFERENTIATION | 9 | 495 | 0.0004564 | 0.004974 |
| 428 | CELLULAR SENESCENCE | 3 | 33 | 0.000465 | 0.005044 |
| 429 | REGULATION OF CELL AGING | 3 | 33 | 0.000465 | 0.005044 |
| 430 | REGULATION OF PROTEIN DEACETYLATION | 3 | 34 | 0.0005083 | 0.005488 |
| 431 | HEART VALVE DEVELOPMENT | 3 | 34 | 0.0005083 | 0.005488 |
| 432 | RAS PROTEIN SIGNAL TRANSDUCTION | 5 | 143 | 0.0005201 | 0.005602 |
| 433 | CELLULAR RESPONSE TO NITROGEN COMPOUND | 9 | 505 | 0.0005272 | 0.005665 |
| 434 | NEGATIVE REGULATION OF CYTOSKELETON ORGANIZATION | 6 | 221 | 0.0005501 | 0.005898 |
| 435 | POSITIVE REGULATION OF AXON EXTENSION | 3 | 36 | 0.0006025 | 0.006415 |
| 436 | POSITIVE REGULATION OF PROTEIN ACETYLATION | 3 | 36 | 0.0006025 | 0.006415 |
| 437 | HEAD MORPHOGENESIS | 3 | 36 | 0.0006025 | 0.006415 |
| 438 | RESPONSE TO TRANSITION METAL NANOPARTICLE | 5 | 148 | 0.0006081 | 0.00646 |
| 439 | POSITIVE REGULATION OF OSSIFICATION | 4 | 84 | 0.0006108 | 0.006474 |
| 440 | REGULATION OF PEPTIDYL THREONINE PHOSPHORYLATION | 3 | 37 | 0.0006535 | 0.006911 |
| 441 | REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS | 6 | 229 | 0.0006629 | 0.006978 |
| 442 | REGULATION OF GENE EXPRESSION EPIGENETIC | 6 | 229 | 0.0006629 | 0.006978 |
| 443 | POSITIVE REGULATION OF DNA REPLICATION | 4 | 86 | 0.0006676 | 0.006996 |
| 444 | POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS | 4 | 86 | 0.0006676 | 0.006996 |
| 445 | RESPONSE TO ACID CHEMICAL | 7 | 319 | 0.0006763 | 0.007071 |
| 446 | TISSUE REMODELING | 4 | 87 | 0.0006973 | 0.007275 |
| 447 | POSITIVE REGULATION OF BIOMINERAL TISSUE DEVELOPMENT | 3 | 38 | 0.0007072 | 0.007328 |
| 448 | TRANSCRIPTION INITIATION FROM RNA POLYMERASE II PROMOTER | 5 | 153 | 0.0007068 | 0.007328 |
| 449 | OOCYTE DIFFERENTIATION | 3 | 38 | 0.0007072 | 0.007328 |
| 450 | OVULATION CYCLE PROCESS | 4 | 88 | 0.0007279 | 0.00751 |
| 451 | NEGATIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY | 4 | 88 | 0.0007279 | 0.00751 |
| 452 | CELL DEVELOPMENT | 16 | 1426 | 0.0007385 | 0.007602 |
| 453 | CELLULAR RESPONSE TO NUTRIENT | 3 | 39 | 0.0007636 | 0.007843 |
| 454 | POSITIVE REGULATION OF DEVELOPMENTAL GROWTH | 5 | 156 | 0.0007715 | 0.007907 |
| 455 | REGULATION OF CELLULAR COMPONENT BIOGENESIS | 11 | 767 | 0.0007811 | 0.00797 |
| 456 | REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS | 13 | 1021 | 0.0007799 | 0.00797 |
| 457 | REGULATION OF CELL MATRIX ADHESION | 4 | 90 | 0.0007921 | 0.008065 |
| 458 | POSITIVE REGULATION OF GROWTH | 6 | 238 | 0.0008103 | 0.008233 |
| 459 | REGULATION OF DEPHOSPHORYLATION | 5 | 158 | 0.000817 | 0.008282 |
| 460 | POSITIVE REGULATION OF CELL MATRIX ADHESION | 3 | 40 | 0.0008227 | 0.008322 |
| 461 | DEVELOPMENTAL GROWTH | 7 | 333 | 0.0008698 | 0.008779 |
| 462 | NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION | 3 | 41 | 0.0008847 | 0.008891 |
| 463 | ANDROGEN RECEPTOR SIGNALING PATHWAY | 3 | 41 | 0.0008847 | 0.008891 |
| 464 | REGULATION OF DNA BINDING | 4 | 93 | 0.0008957 | 0.008982 |
| 465 | DOUBLE STRAND BREAK REPAIR | 5 | 165 | 0.0009922 | 0.009929 |
| Num | GO | Overlap | Size | P Value | Adj. P Value |
|---|---|---|---|---|---|
| 1 | ENZYME BINDING | 44 | 1737 | 7.227e-23 | 6.714e-20 |
| 2 | CYCLIN DEPENDENT PROTEIN SERINE THREONINE KINASE REGULATOR ACTIVITY | 11 | 28 | 2.118e-19 | 9.836e-17 |
| 3 | KINASE BINDING | 26 | 606 | 1.692e-18 | 5.241e-16 |
| 4 | TRANSCRIPTION FACTOR BINDING | 21 | 524 | 2.086e-14 | 4.845e-12 |
| 5 | PROTEIN KINASE ACTIVITY | 21 | 640 | 1.001e-12 | 1.86e-10 |
| 6 | PROTEIN SERINE THREONINE KINASE ACTIVITY | 18 | 445 | 1.644e-12 | 2.545e-10 |
| 7 | CYCLIN DEPENDENT PROTEIN SERINE THREONINE KINASE INHIBITOR ACTIVITY | 6 | 12 | 7.255e-12 | 9.629e-10 |
| 8 | KINASE ACTIVITY | 22 | 842 | 2.337e-11 | 2.713e-09 |
| 9 | KINASE REGULATOR ACTIVITY | 12 | 186 | 5.563e-11 | 5.742e-09 |
| 10 | UBIQUITIN LIKE PROTEIN LIGASE BINDING | 13 | 264 | 2.429e-10 | 2.257e-08 |
| 11 | MACROMOLECULAR COMPLEX BINDING | 26 | 1399 | 4.616e-10 | 3.898e-08 |
| 12 | TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS | 22 | 992 | 5.325e-10 | 4.123e-08 |
| 13 | PROTEIN COMPLEX BINDING | 21 | 935 | 1.134e-09 | 7.879e-08 |
| 14 | RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING | 9 | 104 | 1.187e-09 | 7.879e-08 |
| 15 | PROTEIN SERINE THREONINE KINASE INHIBITOR ACTIVITY | 6 | 30 | 4.363e-09 | 2.702e-07 |
| 16 | CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY | 6 | 34 | 9.737e-09 | 5.653e-07 |
| 17 | CORE PROMOTER BINDING | 9 | 152 | 3.385e-08 | 1.85e-06 |
| 18 | ADENYL NUCLEOTIDE BINDING | 24 | 1514 | 5.562e-08 | 2.871e-06 |
| 19 | CHROMATIN BINDING | 13 | 435 | 9.577e-08 | 4.683e-06 |
| 20 | DNA HELICASE ACTIVITY | 6 | 53 | 1.55e-07 | 7.198e-06 |
| 21 | ACTIVATING TRANSCRIPTION FACTOR BINDING | 6 | 57 | 2.413e-07 | 1.019e-05 |
| 22 | NF KAPPAB BINDING | 5 | 30 | 2.401e-07 | 1.019e-05 |
| 23 | P53 BINDING | 6 | 67 | 6.397e-07 | 2.584e-05 |
| 24 | STEROID HORMONE RECEPTOR BINDING | 6 | 81 | 1.976e-06 | 7.648e-05 |
| 25 | RIBONUCLEOTIDE BINDING | 24 | 1860 | 2.385e-06 | 8.864e-05 |
| 26 | KINASE INHIBITOR ACTIVITY | 6 | 89 | 3.435e-06 | 0.0001182 |
| 27 | TRANSFORMING GROWTH FACTOR BETA RECEPTOR BINDING | 5 | 50 | 3.32e-06 | 0.0001182 |
| 28 | REGULATORY REGION NUCLEIC ACID BINDING | 15 | 818 | 4.577e-06 | 0.0001519 |
| 29 | ENZYME REGULATOR ACTIVITY | 16 | 959 | 7.042e-06 | 0.0002256 |
| 30 | NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY | 18 | 1199 | 7.496e-06 | 0.0002321 |
| 31 | PROTEIN HETERODIMERIZATION ACTIVITY | 11 | 468 | 9.999e-06 | 0.0002903 |
| 32 | DOUBLE STRANDED DNA BINDING | 14 | 764 | 9.95e-06 | 0.0002903 |
| 33 | SMAD BINDING | 5 | 72 | 2.025e-05 | 0.0005533 |
| 34 | CULLIN FAMILY PROTEIN BINDING | 3 | 12 | 2.011e-05 | 0.0005533 |
| 35 | RNA POLYMERASE II ACTIVATING TRANSCRIPTION FACTOR BINDING | 4 | 36 | 2.206e-05 | 0.0005857 |
| 36 | ANDROGEN RECEPTOR BINDING | 4 | 39 | 3.049e-05 | 0.0007867 |
| 37 | DNA DEPENDENT ATPASE ACTIVITY | 5 | 79 | 3.18e-05 | 0.0007985 |
| 38 | MOLECULAR FUNCTION REGULATOR | 18 | 1353 | 3.803e-05 | 0.0009058 |
| 39 | UBIQUITIN LIKE PROTEIN LIGASE ACTIVITY | 7 | 199 | 3.725e-05 | 0.0009058 |
| 40 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR BINDING | 3 | 15 | 4.118e-05 | 0.0009563 |
| 41 | CORE PROMOTER PROXIMAL REGION DNA BINDING | 9 | 371 | 5.288e-05 | 0.001198 |
| 42 | HELICASE ACTIVITY | 6 | 153 | 7.536e-05 | 0.001667 |
| 43 | TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING | 11 | 588 | 8.044e-05 | 0.001738 |
| 44 | CYCLIN BINDING | 3 | 19 | 8.653e-05 | 0.001827 |
| 45 | TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING | 8 | 315 | 0.0001024 | 0.002087 |
| 46 | PHOSPHATASE BINDING | 6 | 162 | 0.0001033 | 0.002087 |
| 47 | PROTEIN N TERMINUS BINDING | 5 | 103 | 0.0001133 | 0.002239 |
| 48 | HORMONE RECEPTOR BINDING | 6 | 168 | 0.0001261 | 0.002391 |
| 49 | HISTONE DEACETYLASE BINDING | 5 | 105 | 0.000124 | 0.002391 |
| 50 | UBIQUITIN LIKE PROTEIN TRANSFERASE ACTIVITY | 9 | 420 | 0.000136 | 0.002526 |
| 51 | RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING | 11 | 629 | 0.0001457 | 0.002653 |
| 52 | R SMAD BINDING | 3 | 23 | 0.0001561 | 0.002788 |
| 53 | DAMAGED DNA BINDING | 4 | 63 | 0.0002029 | 0.003557 |
| 54 | PROTEIN DIMERIZATION ACTIVITY | 15 | 1149 | 0.0002266 | 0.003899 |
| 55 | BHLH TRANSCRIPTION FACTOR BINDING | 3 | 28 | 0.0002839 | 0.004795 |
| 56 | IDENTICAL PROTEIN BINDING | 15 | 1209 | 0.0003903 | 0.006476 |
| 57 | ATP DEPENDENT DNA HELICASE ACTIVITY | 3 | 34 | 0.0005083 | 0.008142 |
| 58 | CHROMATIN DNA BINDING | 4 | 80 | 0.0005077 | 0.008142 |
| 59 | BETA CATENIN BINDING | 4 | 84 | 0.0006108 | 0.009618 |
| Num | GO | Overlap | Size | P Value | Adj. P Value |
|---|---|---|---|---|---|
| 1 | CHROMOSOME | 36 | 880 | 3.26e-25 | 1.904e-22 |
| 2 | NUCLEAR CHROMOSOME | 26 | 523 | 4.413e-20 | 1.289e-17 |
| 3 | CHROMOSOMAL REGION | 22 | 330 | 9.828e-20 | 1.913e-17 |
| 4 | TRANSFERASE COMPLEX | 27 | 703 | 5.403e-18 | 7.889e-16 |
| 5 | CHROMATIN | 22 | 441 | 4.765e-17 | 5.566e-15 |
| 6 | TRANSCRIPTION FACTOR COMPLEX | 19 | 298 | 9.452e-17 | 9.2e-15 |
| 7 | CATALYTIC COMPLEX | 28 | 1038 | 9.771e-15 | 8.152e-13 |
| 8 | CYCLIN DEPENDENT PROTEIN KINASE HOLOENZYME COMPLEX | 9 | 31 | 1.145e-14 | 8.36e-13 |
| 9 | MCM COMPLEX | 6 | 11 | 3.641e-12 | 2.363e-10 |
| 10 | CULLIN RING UBIQUITIN LIGASE COMPLEX | 12 | 150 | 4.401e-12 | 2.57e-10 |
| 11 | ANAPHASE PROMOTING COMPLEX | 7 | 22 | 5.569e-12 | 2.957e-10 |
| 12 | PROTEIN KINASE COMPLEX | 10 | 90 | 1.086e-11 | 5.287e-10 |
| 13 | NUCLEAR UBIQUITIN LIGASE COMPLEX | 8 | 42 | 1.526e-11 | 6.854e-10 |
| 14 | CHROMOSOME TELOMERIC REGION | 11 | 162 | 2.137e-10 | 8.914e-09 |
| 15 | CHROMOSOME CENTROMERIC REGION | 11 | 174 | 4.595e-10 | 1.789e-08 |
| 16 | TRANSFERASE COMPLEX TRANSFERRING PHOSPHORUS CONTAINING GROUPS | 12 | 237 | 9.124e-10 | 3.33e-08 |
| 17 | MICROTUBULE CYTOSKELETON | 22 | 1068 | 2.106e-09 | 7.235e-08 |
| 18 | UBIQUITIN LIGASE COMPLEX | 12 | 262 | 2.846e-09 | 9.235e-08 |
| 19 | CONDENSED NUCLEAR CHROMOSOME | 8 | 85 | 5.297e-09 | 1.628e-07 |
| 20 | SPINDLE | 12 | 289 | 8.557e-09 | 2.499e-07 |
| 21 | NUCLEAR CHROMOSOME TELOMERIC REGION | 9 | 132 | 9.873e-09 | 2.746e-07 |
| 22 | CONDENSED CHROMOSOME | 10 | 195 | 2.221e-08 | 5.896e-07 |
| 23 | CONDENSED CHROMOSOME OUTER KINETOCHORE | 4 | 12 | 2.018e-07 | 5.123e-06 |
| 24 | RNA POLYMERASE II TRANSCRIPTION FACTOR COMPLEX | 7 | 101 | 4.185e-07 | 1.018e-05 |
| 25 | CONDENSED CHROMOSOME CENTROMERIC REGION | 7 | 102 | 4.477e-07 | 1.046e-05 |
| 26 | CONDENSED NUCLEAR CHROMOSOME CENTROMERIC REGION | 4 | 18 | 1.221e-06 | 2.743e-05 |
| 27 | KINETOCHORE | 7 | 120 | 1.349e-06 | 2.917e-05 |
| 28 | SPINDLE POLE | 7 | 126 | 1.872e-06 | 3.904e-05 |
| 29 | NUCLEAR TRANSCRIPTION FACTOR COMPLEX | 7 | 127 | 1.974e-06 | 3.975e-05 |
| 30 | CENTROSOME | 12 | 487 | 2.356e-06 | 4.587e-05 |
| 31 | MICROTUBULE ORGANIZING CENTER | 13 | 623 | 5.358e-06 | 0.0001009 |
| 32 | CYTOSKELETAL PART | 20 | 1436 | 6.561e-06 | 0.0001197 |
| 33 | NUCLEAR CHROMATIN | 9 | 291 | 7.805e-06 | 0.0001381 |
| 34 | COHESIN COMPLEX | 3 | 11 | 1.513e-05 | 0.0002599 |
| 35 | SCF UBIQUITIN LIGASE COMPLEX | 4 | 34 | 1.749e-05 | 0.0002919 |
| 36 | CYTOSKELETON | 23 | 1967 | 2.071e-05 | 0.000336 |
| 37 | NUCLEOLUS | 14 | 848 | 3.171e-05 | 0.0005005 |
| 38 | CARBOXY TERMINAL DOMAIN PROTEIN KINASE COMPLEX | 3 | 22 | 0.0001362 | 0.002092 |
| 39 | REPLICATION FORK | 4 | 62 | 0.0001907 | 0.002856 |
| 40 | SPINDLE MIDZONE | 3 | 27 | 0.0002543 | 0.003713 |
| 41 | TRANSCRIPTIONAL REPRESSOR COMPLEX | 4 | 74 | 0.0003772 | 0.005373 |
| 42 | NUCLEOPLASM PART | 11 | 708 | 0.0004018 | 0.005586 |
| 43 | PERINUCLEAR REGION OF CYTOPLASM | 10 | 642 | 0.0007325 | 0.009948 |
Over-represented Pathway
| Num | Pathway | Pathview | Overlap | Size | P Value | Adj. P Value |
|---|---|---|---|---|---|---|
| 1 | hsa04110_Cell_cycle | 92 | 128 | 2.582e-222 | 4.647e-220 | |
| 2 | hsa04114_Oocyte_meiosis | 26 | 114 | 8.885e-38 | 7.997e-36 | |
| 3 | hsa04115_p53_signaling_pathway | 20 | 69 | 1.91e-31 | 1.146e-29 | |
| 4 | hsa04350_TGF.beta_signaling_pathway | 17 | 85 | 9.658e-24 | 4.346e-22 | |
| 5 | hsa04914_Progesterone.mediated_oocyte_maturation | 15 | 87 | 5.33e-20 | 1.919e-18 | |
| 6 | hsa04390_Hippo_signaling_pathway | 16 | 154 | 1.316e-17 | 3.949e-16 | |
| 7 | hsa04151_PI3K_AKT_signaling_pathway | 19 | 351 | 1.925e-15 | 4.95e-14 | |
| 8 | hsa04310_Wnt_signaling_pathway | 14 | 151 | 8.056e-15 | 1.813e-13 | |
| 9 | hsa04120_Ubiquitin_mediated_proteolysis | 11 | 139 | 4.073e-11 | 8.147e-10 | |
| 10 | hsa03030_DNA_replication | 7 | 36 | 2.587e-10 | 4.657e-09 | |
| 11 | hsa04722_Neurotrophin_signaling_pathway | 7 | 127 | 1.974e-06 | 3.23e-05 | |
| 12 | hsa04010_MAPK_signaling_pathway | 9 | 268 | 4.011e-06 | 6.017e-05 | |
| 13 | hsa04520_Adherens_junction | 5 | 73 | 2.166e-05 | 0.0002999 | |
| 14 | hsa03420_Nucleotide_excision_repair | 4 | 45 | 5.407e-05 | 0.0006952 | |
| 15 | hsa04330_Notch_signaling_pathway | 4 | 47 | 6.428e-05 | 0.0007713 | |
| 16 | hsa04630_Jak.STAT_signaling_pathway | 6 | 155 | 8.098e-05 | 0.000911 | |
| 17 | hsa04710_Circadian_rhythm_._mammal | 3 | 23 | 0.0001561 | 0.001652 | |
| 18 | hsa04144_Endocytosis | 6 | 203 | 0.0003508 | 0.003508 | |
| 19 | hsa04012_ErbB_signaling_pathway | 4 | 87 | 0.0006973 | 0.006606 | |
| 20 | hsa04916_Melanogenesis | 3 | 101 | 0.01135 | 0.1021 | |
| 21 | hsa04510_Focal_adhesion | 4 | 200 | 0.01369 | 0.1173 | |
| 22 | hsa04720_Long.term_potentiation | 2 | 70 | 0.0413 | 0.3325 | |
| 23 | hsa04141_Protein_processing_in_endoplasmic_reticulum | 3 | 168 | 0.04249 | 0.3325 | |
| 24 | hsa04210_Apoptosis | 2 | 89 | 0.06336 | 0.4562 | |
| 25 | hsa04660_T_cell_receptor_signaling_pathway | 2 | 108 | 0.08847 | 0.6125 | |
| 26 | hsa04380_Osteoclast_differentiation | 2 | 128 | 0.1175 | 0.7552 |
lncRNA-mediated sponge
| Num | lncRNA | miRNAs | miRNAs count | Gene | Sponge regulatory network | lncRNA log2FC | lncRNA pvalue | Gene log2FC | Gene pvalue | lncRNA-gene Pearson correlation |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | FOXD2-AS1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p | 11 | E2F2 | Sponge network | 2.209 | 0 | 2.823 | 0 | 0.686 |
| 2 | SNHG1 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p | 13 | E2F2 | Sponge network | 2.013 | 0 | 2.823 | 0 | 0.684 |
| 3 | SNHG1 |
hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-486-5p | 10 | CCNA2 | Sponge network | 2.013 | 0 | 3.368 | 0 | 0.678 |
| 4 | TMPO-AS1 |
hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-1-5p;hsa-miR-29b-3p;hsa-miR-29c-3p | 11 | CCNA2 | Sponge network | 2.165 | 0 | 3.368 | 0 | 0.67 |
| 5 | MAFG-AS1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 14 | E2F2 | Sponge network | 2.966 | 0 | 2.823 | 0 | 0.66 |
| 6 | MAPKAPK5-AS1 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-3614-5p | 11 | E2F2 | Sponge network | 1.411 | 0 | 2.823 | 0 | 0.659 |
| 7 | RP5-1074L1.4 | hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-1-5p;hsa-miR-29c-3p;hsa-miR-486-5p | 11 | CCNA2 | Sponge network | 2.302 | 0 | 3.368 | 0 | 0.658 |
| 8 | LINC00205 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-378a-3p;hsa-miR-378c | 12 | E2F2 | Sponge network | 1.978 | 0 | 2.823 | 0 | 0.655 |
| 9 | RP11-498C9.15 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-3614-5p;hsa-miR-378a-3p | 13 | E2F2 | Sponge network | 1.487 | 0 | 2.823 | 0 | 0.642 |
| 10 | PTOV1-AS1 | hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 1.252 | 0 | 2.823 | 0 | 0.63 |
| 11 | SNHG12 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 13 | E2F2 | Sponge network | 1.791 | 0 | 2.823 | 0 | 0.626 |
| 12 | AP001469.9 |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-1-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-486-5p | 13 | CCNA2 | Sponge network | 2.428 | 0 | 3.368 | 0 | 0.619 |
| 13 | AP001469.9 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p | 11 | E2F2 | Sponge network | 2.428 | 0 | 2.823 | 0 | 0.618 |
| 14 | DYNLL1-AS1 | hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 11 | E2F2 | Sponge network | 1.231 | 0 | 2.823 | 0 | 0.616 |
| 15 | MYLK-AS1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p | 11 | E2F2 | Sponge network | 2.852 | 0 | 2.823 | 0 | 0.616 |
| 16 | TMPO-AS1 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326 | 13 | E2F2 | Sponge network | 2.165 | 0 | 2.823 | 0 | 0.614 |
| 17 | RP11-196G18.22 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-3614-5p | 11 | E2F2 | Sponge network | 2.705 | 0 | 2.823 | 0 | 0.612 |
| 18 | RP11-1246C19.1 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p | 12 | E2F2 | Sponge network | 2.721 | 0 | 2.823 | 0 | 0.612 |
| 19 | KDM4A-AS1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378c | 13 | E2F2 | Sponge network | 1.493 | 0 | 2.823 | 0 | 0.608 |
| 20 | RP11-600F24.7 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 15 | E2F2 | Sponge network | 2.603 | 0 | 2.823 | 0 | 0.607 |
| 21 | MAPKAPK5-AS1 |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29c-3p;hsa-miR-486-5p | 10 | CCNA2 | Sponge network | 1.411 | 0 | 3.368 | 0 | 0.604 |
| 22 | CTC-459F4.3 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 14 | E2F2 | Sponge network | 1.207 | 0 | 2.823 | 0 | 0.603 |
| 23 | RP4-758J18.13 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p | 10 | E2F2 | Sponge network | 1.374 | 0 | 2.823 | 0 | 0.602 |
| 24 | LINC00152 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p | 13 | E2F2 | Sponge network | 2.553 | 0 | 2.823 | 0 | 0.596 |
| 25 | KB-1572G7.2 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 15 | E2F2 | Sponge network | 2.124 | 0 | 2.823 | 0 | 0.595 |
| 26 | MIR4435-1HG | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 14 | E2F2 | Sponge network | 2.541 | 0 | 2.823 | 0 | 0.595 |
| 27 | PXN-AS1 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326 | 13 | E2F2 | Sponge network | 1.561 | 0 | 2.823 | 0 | 0.595 |
| 28 | PXN-AS1 |
hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-1-5p;hsa-miR-29b-3p;hsa-miR-29c-3p | 11 | CCNA2 | Sponge network | 1.561 | 0 | 3.368 | 0 | 0.591 |
| 29 | AP001258.4 | hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 1.249 | 0 | 2.823 | 0 | 0.591 |
| 30 | AP006222.2 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-378a-3p;hsa-miR-378c | 12 | E2F2 | Sponge network | 1.709 | 0 | 2.823 | 0 | 0.589 |
| 31 | GUSBP11 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 15 | E2F2 | Sponge network | 2.066 | 0 | 2.823 | 0 | 0.582 |
| 32 | RP1-228H13.5 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p | 11 | E2F2 | Sponge network | 1.554 | 0 | 2.823 | 0 | 0.579 |
| 33 | LINC00528 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 13 | E2F2 | Sponge network | 1.854 | 0 | 2.823 | 0 | 0.572 |
| 34 | FLVCR1-AS1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 15 | E2F2 | Sponge network | 2.147 | 0 | 2.823 | 0 | 0.569 |
| 35 | RP11-435O5.2 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-378a-3p;hsa-miR-378c | 14 | E2F2 | Sponge network | 2.087 | 0 | 2.823 | 0 | 0.566 |
| 36 | RP11-398C13.6 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p | 10 | E2F2 | Sponge network | 1.768 | 0 | 2.823 | 0 | 0.564 |
| 37 | BAIAP2-AS1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 14 | E2F2 | Sponge network | 1.249 | 0 | 2.823 | 0 | 0.56 |
| 38 | TMCC1-AS1 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-326;hsa-miR-3614-5p | 10 | E2F2 | Sponge network | 2.298 | 0 | 2.823 | 0 | 0.558 |
| 39 | RP11-1246C19.1 |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29c-3p | 10 | CCNA2 | Sponge network | 2.721 | 0 | 3.368 | 0 | 0.556 |
| 40 | PRKAR2A-AS1 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 15 | E2F2 | Sponge network | 2.366 | 0 | 2.823 | 0 | 0.556 |
| 41 | RP11-216L13.19 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 13 | E2F2 | Sponge network | 2.404 | 0 | 2.823 | 0 | 0.555 |
| 42 | KB-1572G7.3 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p | 10 | E2F2 | Sponge network | 2.031 | 0 | 2.823 | 0 | 0.549 |
| 43 | RP11-412D9.4 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p | 10 | E2F2 | Sponge network | 1.247 | 0 | 2.823 | 0 | 0.546 |
| 44 | GAS5 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-3614-5p | 11 | E2F2 | Sponge network | 1.966 | 0 | 2.823 | 0 | 0.546 |
| 45 | RP5-882C2.2 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 12 | E2F2 | Sponge network | 1.879 | 0 | 2.823 | 0 | 0.544 |
| 46 | RP4-717I23.3 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-3614-5p | 11 | E2F2 | Sponge network | 1.867 | 0 | 2.823 | 0 | 0.544 |
| 47 | GUSBP11 |
hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-1-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-486-5p | 11 | CCNA2 | Sponge network | 2.066 | 0 | 3.368 | 0 | 0.54 |
| 48 | CTB-31O20.2 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 1.649 | 0 | 2.823 | 0 | 0.538 |
| 49 | AC074117.10 |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29c-3p | 10 | CCNA2 | Sponge network | 1.254 | 0 | 3.368 | 0 | 0.537 |
| 50 | AC006538.1 | hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 13 | E2F2 | Sponge network | 3.027 | 0 | 2.823 | 0 | 0.536 |
| 51 | RP5-1120P11.1 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26b-5p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 12 | E2F2 | Sponge network | 3.942 | 0 | 2.823 | 0 | 0.533 |
| 52 | TMCC1-AS1 |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29c-3p | 10 | CCNA2 | Sponge network | 2.298 | 0 | 3.368 | 0 | 0.533 |
| 53 | AC016747.3 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 12 | E2F2 | Sponge network | 1.235 | 0 | 2.823 | 0 | 0.533 |
| 54 | AC025171.1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 13 | E2F2 | Sponge network | 2.476 | 0 | 2.823 | 0 | 0.532 |
| 55 | SNHG7 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326 | 11 | E2F2 | Sponge network | 2.077 | 0 | 2.823 | 0 | 0.529 |
| 56 | AC009005.2 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p | 10 | E2F2 | Sponge network | 2.488 | 0 | 2.823 | 0 | 0.522 |
| 57 | AC005154.6 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 13 | E2F2 | Sponge network | 1.75 | 0 | 2.823 | 0 | 0.521 |
| 58 | RP11-495P10.5 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-3614-5p | 13 | E2F2 | Sponge network | 7.839 | 0 | 2.823 | 0 | 0.52 |
| 59 | PRKAR2A-AS1 |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29c-3p | 10 | CCNA2 | Sponge network | 2.366 | 0 | 3.368 | 0 | 0.52 |
| 60 | RP11-37B2.1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 13 | E2F2 | Sponge network | 1.504 | 0 | 2.823 | 0 | 0.517 |
| 61 | PVT1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 12 | E2F2 | Sponge network | 2.645 | 0 | 2.823 | 0 | 0.515 |
| 62 | NPSR1-AS1 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p | 14 | E2F2 | Sponge network | 5.28 | 0 | 2.823 | 0 | 0.512 |
| 63 | RHPN1-AS1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-378a-3p;hsa-miR-378c | 12 | E2F2 | Sponge network | 1.895 | 0 | 2.823 | 0 | 0.511 |
| 64 | HOTTIP |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 14 | E2F2 | Sponge network | 7.501 | 0 | 2.823 | 0 | 0.508 |
| 65 | NPSR1-AS1 |
hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-486-5p | 10 | CCNA2 | Sponge network | 5.28 | 0 | 3.368 | 0 | 0.505 |
| 66 | CTC-338M12.4 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 14 | E2F2 | Sponge network | 1.926 | 0 | 2.823 | 0 | 0.504 |
| 67 | CTA-228A9.3 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-3614-5p | 11 | E2F2 | Sponge network | 2.412 | 0 | 2.823 | 0 | 0.502 |
| 68 | CTD-2561J22.5 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26b-5p;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 2.129 | 0 | 2.823 | 0 | 0.501 |
| 69 | RP11-521B24.3 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 13 | E2F2 | Sponge network | 1.62 | 0 | 2.823 | 0 | 0.499 |
| 70 | RP11-727A23.5 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 14 | E2F2 | Sponge network | 1.435 | 0 | 2.823 | 0 | 0.496 |
| 71 | LINC01011 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326 | 10 | E2F2 | Sponge network | 1.861 | 0 | 2.823 | 0 | 0.496 |
| 72 | RP11-295G20.2 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p | 11 | E2F2 | Sponge network | 2.208 | 0 | 2.823 | 0 | 0.495 |
| 73 | SNHG7 |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29c-3p;hsa-miR-486-5p | 10 | CCNA2 | Sponge network | 2.077 | 0 | 3.368 | 0 | 0.494 |
| 74 | HOXA11-AS | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-326 | 10 | E2F2 | Sponge network | 6.056 | 0 | 2.823 | 0 | 0.491 |
| 75 | CTC-338M12.4 |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29c-3p | 10 | CCNA2 | Sponge network | 1.926 | 0 | 3.368 | 0 | 0.491 |
| 76 | RP11-611E13.2 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326 | 11 | E2F2 | Sponge network | 1.148 | 0 | 2.823 | 0 | 0.486 |
| 77 | HCG18 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 12 | E2F2 | Sponge network | 1.42 | 0 | 2.823 | 0 | 0.485 |
| 78 | BX322557.10 | hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 11 | E2F2 | Sponge network | 1.565 | 0 | 2.823 | 0 | 0.482 |
| 79 | ZFAS1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-378a-3p;hsa-miR-378c | 11 | E2F2 | Sponge network | 1.155 | 0 | 2.823 | 0 | 0.48 |
| 80 | RP11-328N19.1 |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29c-3p | 10 | CCNA2 | Sponge network | 7.657 | 0 | 3.368 | 0 | 0.48 |
| 81 | TFAP2A-AS1 | hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 5.572 | 0 | 2.823 | 0 | 0.478 |
| 82 | CITF22-92A6.1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p | 10 | E2F2 | Sponge network | 1.409 | 0 | 2.823 | 0 | 0.478 |
| 83 | RP11-328N19.1 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-2-3p | 11 | E2F2 | Sponge network | 7.657 | 0 | 2.823 | 0 | 0.476 |
| 84 | AC098820.3 | hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-29a-3p;hsa-miR-29b-1-5p;hsa-miR-29b-3p;hsa-miR-29c-3p | 10 | CCNA2 | Sponge network | 1.898 | 0 | 3.368 | 0 | 0.475 |
| 85 | RAB30-AS1 |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-486-5p | 10 | CCNA2 | Sponge network | 1.001 | 0 | 3.368 | 0 | 0.475 |
| 86 | CTC-429P9.3 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-130a-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p | 10 | E2F2 | Sponge network | 1.449 | 0 | 2.823 | 0 | 0.473 |
| 87 | RP11-1055B8.4 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326 | 10 | E2F2 | Sponge network | 2.726 | 0 | 2.823 | 0 | 0.472 |
| 88 | RAB30-AS1 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-2-3p;hsa-miR-3614-5p | 10 | E2F2 | Sponge network | 1.001 | 0 | 2.823 | 0 | 0.472 |
| 89 | AC159540.1 | hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p | 10 | E2F2 | Sponge network | 2.112 | 0 | 2.823 | 0 | 0.47 |
| 90 | RP11-284F21.7 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-204-5p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p | 10 | E2F2 | Sponge network | 7.525 | 0 | 2.823 | 0 | 0.47 |
| 91 | RP11-727A23.5 |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-1-5p;hsa-miR-29c-3p;hsa-miR-486-5p | 12 | CCNA2 | Sponge network | 1.435 | 0 | 3.368 | 0 | 0.468 |
| 92 | AC074117.10 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-2-3p;hsa-miR-326 | 11 | E2F2 | Sponge network | 1.254 | 0 | 2.823 | 0 | 0.466 |
| 93 | KB-1460A1.5 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-378a-3p;hsa-miR-378c | 12 | E2F2 | Sponge network | 1.949 | 0 | 2.823 | 0 | 0.466 |
| 94 | RP5-1120P11.1 |
hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-1-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-486-5p | 12 | CCNA2 | Sponge network | 3.942 | 0 | 3.368 | 0 | 0.465 |
| 95 | RP11-465N4.4 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 14 | E2F2 | Sponge network | 1.938 | 0 | 2.823 | 0 | 0.463 |
| 96 | RP11-324I22.4 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p | 10 | E2F2 | Sponge network | 1.448 | 0 | 2.823 | 0 | 0.461 |
| 97 | GS1-124K5.11 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 13 | E2F2 | Sponge network | 1.5 | 0 | 2.823 | 0 | 0.461 |
| 98 | TEX41 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-30c-2-3p;hsa-miR-3614-5p;hsa-miR-378c | 10 | E2F2 | Sponge network | 3.293 | 0 | 2.823 | 0 | 0.46 |
| 99 | HCG18 |
hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-486-5p | 10 | CCNA2 | Sponge network | 1.42 | 0 | 3.368 | 0 | 0.457 |
| 100 | LINC00680 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 1.404 | 0 | 2.823 | 0 | 0.457 |
| 101 | MIR210HG | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-30c-2-3p;hsa-miR-378a-3p;hsa-miR-378c | 11 | E2F2 | Sponge network | 0.936 | 0.00012 | 2.823 | 0 | 0.456 |
| 102 | CTD-3220F14.1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p | 11 | E2F2 | Sponge network | 3.223 | 0 | 2.823 | 0 | 0.454 |
| 103 | MALAT1 | hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-22-3p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 1.297 | 0 | 2.823 | 0 | 0.453 |
| 104 | TEX41 |
hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p | 10 | CCNA2 | Sponge network | 3.293 | 0 | 3.368 | 0 | 0.452 |
| 105 | HOTTIP |
hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p | 10 | CCNA2 | Sponge network | 7.501 | 0 | 3.368 | 0 | 0.452 |
| 106 | HLA-F-AS1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-378a-3p;hsa-miR-378c | 11 | E2F2 | Sponge network | 1.71 | 0 | 2.823 | 0 | 0.448 |
| 107 | RP11-284F21.9 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 12 | E2F2 | Sponge network | 4.745 | 0 | 2.823 | 0 | 0.446 |
| 108 | SNHG17 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 1.214 | 0 | 2.823 | 0 | 0.442 |
| 109 | RP11-458D21.1 |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p | 11 | CCNA2 | Sponge network | 1.399 | 0 | 3.368 | 0 | 0.439 |
| 110 | RP11-383J24.1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p | 10 | E2F2 | Sponge network | 5.821 | 0 | 2.823 | 0 | 0.438 |
| 111 | PSMD5-AS1 | hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p | 10 | E2F2 | Sponge network | 1.538 | 0 | 2.823 | 0 | 0.437 |
| 112 | CDIPT-AS1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326 | 13 | E2F2 | Sponge network | 3.447 | 0 | 2.823 | 0 | 0.436 |
| 113 | AC062029.1 | hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29c-3p | 10 | CCNA2 | Sponge network | 1.067 | 0 | 3.368 | 0 | 0.435 |
| 114 | RP11-20I23.13 | hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 12 | E2F2 | Sponge network | 1.015 | 0 | 2.823 | 0 | 0.435 |
| 115 | LINC00638 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326 | 12 | E2F2 | Sponge network | 1.756 | 0 | 2.823 | 0 | 0.433 |
| 116 | SNHG11 | hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326 | 10 | E2F2 | Sponge network | 1.239 | 0 | 2.823 | 0 | 0.429 |
| 117 | RP11-540A21.2 |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-486-5p | 12 | CCNA2 | Sponge network | 1.758 | 0 | 3.368 | 0 | 0.425 |
| 118 | AC006547.13 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 11 | E2F2 | Sponge network | 1.39 | 0 | 2.823 | 0 | 0.423 |
| 119 | RP11-133K1.6 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 13 | E2F2 | Sponge network | 1.056 | 0 | 2.823 | 0 | 0.42 |
| 120 | RP13-582O9.5 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-3614-5p | 11 | E2F2 | Sponge network | 2.071 | 0 | 2.823 | 0 | 0.42 |
| 121 | CTD-2228K2.7 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 13 | E2F2 | Sponge network | 2.28 | 0 | 2.823 | 0 | 0.419 |
| 122 | RP5-1165K10.2 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 11 | E2F2 | Sponge network | 1.401 | 0 | 2.823 | 0 | 0.419 |
| 123 | RP11-296I10.3 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 11 | E2F2 | Sponge network | 1.287 | 0 | 2.823 | 0 | 0.419 |
| 124 | CTD-3138B18.5 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-3614-5p | 11 | E2F2 | Sponge network | 1.228 | 0 | 2.823 | 0 | 0.418 |
| 125 | CTD-3162L10.1 | hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378c | 11 | E2F2 | Sponge network | 3.111 | 0 | 2.823 | 0 | 0.418 |
| 126 | RP11-523H20.3 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 2.494 | 0 | 2.823 | 0 | 0.414 |
| 127 | RP11-440L14.1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 1.681 | 0 | 2.823 | 0 | 0.414 |
| 128 | AC012146.7 | hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29c-3p | 10 | CCNA2 | Sponge network | 1.709 | 0 | 3.368 | 0 | 0.413 |
| 129 | TMEM161B-AS1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-326 | 10 | E2F2 | Sponge network | 1.593 | 0 | 2.823 | 0 | 0.413 |
| 130 | LRP4-AS1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 13 | E2F2 | Sponge network | 5.408 | 0 | 2.823 | 0 | 0.412 |
| 131 | ERVK3-1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 1.328 | 0 | 2.823 | 0 | 0.411 |
| 132 | LINC00355 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p | 10 | E2F2 | Sponge network | 6.198 | 0 | 2.823 | 0 | 0.408 |
| 133 | RP11-20J15.2 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-204-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 4.744 | 0 | 2.823 | 0 | 0.408 |
| 134 | FEZF1-AS1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-214-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-2-3p;hsa-miR-378c | 12 | E2F2 | Sponge network | 5.616 | 0 | 2.823 | 0 | 0.408 |
| 135 | CTBP1-AS2 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 13 | E2F2 | Sponge network | 1.419 | 0 | 2.823 | 0 | 0.407 |
| 136 | POLR2J4 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 13 | E2F2 | Sponge network | 1.386 | 0 | 2.823 | 0 | 0.406 |
| 137 | CTBP1-AS2 |
hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-486-5p | 10 | CCNA2 | Sponge network | 1.419 | 0 | 3.368 | 0 | 0.406 |
| 138 | RP5-1092A3.4 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-26a-5p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p | 10 | E2F2 | Sponge network | 1.141 | 0 | 2.823 | 0 | 0.406 |
| 139 | RP11-212P7.2 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-3614-5p | 10 | E2F2 | Sponge network | 1.561 | 0 | 2.823 | 0 | 0.406 |
| 140 | LINC00511 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 12 | E2F2 | Sponge network | 2.468 | 0 | 2.823 | 0 | 0.405 |
| 141 | RP11-175O19.4 | hsa-miR-193b-3p;hsa-miR-195-3p;hsa-miR-22-3p;hsa-miR-28-5p;hsa-miR-30c-5p;hsa-miR-30e-5p;hsa-miR-328-3p;hsa-miR-378a-3p;hsa-miR-455-3p;hsa-miR-505-5p | 10 | YWHAZ | Sponge network | 0.743 | 0 | 0.521 | 0 | 0.405 |
| 142 | LINC00665 | hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 11 | E2F2 | Sponge network | 2.394 | 0 | 2.823 | 0 | 0.401 |
| 143 | RP11-110G21.1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 12 | E2F2 | Sponge network | 1.338 | 0 | 2.823 | 0 | 0.398 |
| 144 | RP11-159D12.2 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 13 | E2F2 | Sponge network | 1.574 | 0 | 2.823 | 0 | 0.394 |
| 145 | RP11-89K21.1 | hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p | 11 | E2F2 | Sponge network | 4.915 | 0 | 2.823 | 0 | 0.391 |
| 146 | HNRNPU-AS1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-3614-5p | 10 | E2F2 | Sponge network | 1.246 | 0 | 2.823 | 0 | 0.385 |
| 147 | CTC-273B12.5 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 1.769 | 0 | 2.823 | 0 | 0.381 |
| 148 | RP11-774D14.1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-30c-2-3p;hsa-miR-326 | 11 | E2F2 | Sponge network | 6.64 | 0 | 2.823 | 0 | 0.376 |
| 149 | RP11-440G9.1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-3614-5p | 10 | E2F2 | Sponge network | 4.78 | 0 | 2.823 | 0 | 0.374 |
| 150 | RP11-3P17.4 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 11 | E2F2 | Sponge network | 1.24 | 0 | 2.823 | 0 | 0.373 |
| 151 | NOP14-AS1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-326;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 12 | E2F2 | Sponge network | 1.279 | 0 | 2.823 | 0 | 0.372 |
| 152 | LINC00482 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-204-5p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326 | 11 | E2F2 | Sponge network | 1.884 | 0 | 2.823 | 0 | 0.369 |
| 153 | KB-431C1.4 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 12 | E2F2 | Sponge network | 1.573 | 0 | 2.823 | 0 | 0.361 |
| 154 | DNM1P35 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378c | 11 | E2F2 | Sponge network | 1.581 | 0 | 2.823 | 0 | 0.36 |
| 155 | MAGI2-AS3 | hsa-miR-106b-5p;hsa-miR-1266-5p;hsa-miR-15b-5p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-589-3p;hsa-miR-616-5p;hsa-miR-9-5p;hsa-miR-92a-3p;hsa-miR-93-5p | 13 | CCND1 | Sponge network | -1.801 | 0 | -0.902 | 1.0E-5 | 0.359 |
| 156 | NUTM2A-AS1 | hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-1-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-486-5p | 10 | CCNA2 | Sponge network | 0.788 | 0 | 3.368 | 0 | 0.358 |
| 157 | LINC00176 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326 | 11 | E2F2 | Sponge network | 3.423 | 0 | 2.823 | 0 | 0.354 |
| 158 | RP11-540A21.2 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-378a-3p;hsa-miR-378c | 13 | E2F2 | Sponge network | 1.758 | 0 | 2.823 | 0 | 0.352 |
| 159 | ZNRD1-AS1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 11 | E2F2 | Sponge network | 1.284 | 0 | 2.823 | 0 | 0.352 |
| 160 | DNM1P35 |
hsa-let-7a-3p;hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-29a-3p;hsa-miR-29b-1-5p;hsa-miR-29b-3p;hsa-miR-29c-3p | 11 | CCNA2 | Sponge network | 1.581 | 0 | 3.368 | 0 | 0.351 |
| 161 | FAM83H-AS1 | hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 1.49 | 0 | 2.823 | 0 | 0.351 |
| 162 | AC084219.4 | hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-2-3p;hsa-miR-3614-5p;hsa-miR-378c | 10 | E2F2 | Sponge network | 3.914 | 0 | 2.823 | 0 | 0.348 |
| 163 | RP11-704M14.1 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p | 10 | E2F2 | Sponge network | 2.871 | 0 | 2.823 | 0 | 0.346 |
| 164 | RP11-263K19.4 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 11 | E2F2 | Sponge network | 2.267 | 0 | 2.823 | 0 | 0.339 |
| 165 | ZNF503-AS2 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 1.201 | 0 | 2.823 | 0 | 0.334 |
| 166 | CTD-2587H24.10 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326 | 10 | E2F2 | Sponge network | 1.662 | 0 | 2.823 | 0 | 0.33 |
| 167 | LINC00624 | hsa-let-7b-3p;hsa-miR-130a-3p;hsa-miR-199a-5p;hsa-miR-22-3p;hsa-miR-27b-3p;hsa-miR-29a-3p;hsa-miR-29b-1-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-486-5p | 10 | CCNA2 | Sponge network | 3.71 | 0 | 3.368 | 0 | 0.324 |
| 168 | SSTR5-AS1 | hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-204-5p;hsa-miR-22-3p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-3614-5p;hsa-miR-378a-3p;hsa-miR-378c | 11 | E2F2 | Sponge network | 3.192 | 0.00084 | 2.823 | 0 | 0.324 |
| 169 | RP11-458D21.1 |
hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-326;hsa-miR-3614-5p | 10 | E2F2 | Sponge network | 1.399 | 0 | 2.823 | 0 | 0.323 |
| 170 | AP000487.5 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p | 11 | E2F2 | Sponge network | 1.775 | 0 | 2.823 | 0 | 0.314 |
| 171 | RP5-1061H20.4 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125a-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-326 | 10 | E2F2 | Sponge network | 1.313 | 0 | 2.823 | 0 | 0.297 |
| 172 | PSMG3-AS1 | hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 1.372 | 0 | 2.823 | 0 | 0.285 |
| 173 | AC073283.4 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-let-7g-5p;hsa-miR-125b-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-30c-1-3p;hsa-miR-30c-2-3p;hsa-miR-326;hsa-miR-3614-5p | 11 | E2F2 | Sponge network | 1.514 | 0 | 2.823 | 0 | 0.278 |
| 174 | RP11-983P16.4 | hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7f-1-3p;hsa-miR-130a-3p;hsa-miR-22-3p;hsa-miR-29a-3p;hsa-miR-29b-1-5p;hsa-miR-29b-3p;hsa-miR-29c-3p;hsa-miR-486-5p | 10 | CCNA2 | Sponge network | 0.673 | 0 | 3.368 | 0 | 0.266 |
| 175 | HOXD-AS2 | hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-214-5p;hsa-miR-22-3p;hsa-miR-26a-5p;hsa-miR-26b-5p;hsa-miR-378a-3p;hsa-miR-378c | 10 | E2F2 | Sponge network | 5.013 | 0 | 2.823 | 0 | 0.266 |
| 176 | RP11-166D19.1 | hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1266-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-425-5p;hsa-miR-589-3p;hsa-miR-616-5p;hsa-miR-92a-3p;hsa-miR-942-5p | 16 | CCND1 | Sponge network | -0.244 | 0.28835 | -0.902 | 1.0E-5 | 0.253 |