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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-590-3p AASS 2.59 0 -1.35 5.0E-5 MirTarget; miRanda -0.3 0 NA
2 hsa-miR-27a-5p ABAT 0.05 0.86909 -0.34 0.43051 miRNATAP -0.15 0.01744 NA
3 hsa-miR-590-3p ABAT 2.59 0 -0.34 0.43051 PITA; miRanda -0.27 0.00042 NA
4 hsa-miR-361-5p ABCA1 0.97 0 -0.71 0.00276 miRanda; mirMAP -0.32 0 NA
5 hsa-miR-454-3p ABCA1 2.47 0 -0.71 0.00276 miRNATAP -0.17 0.00013 NA
6 hsa-miR-342-3p ABCA6 1.49 0 -2.84 1.0E-5 miRanda -0.27 0.01159 NA
7 hsa-miR-590-3p ABCA6 2.59 0 -2.84 1.0E-5 MirTarget; miRanda -0.47 2.0E-5 NA
8 hsa-miR-361-5p ABCA8 0.97 0 -5.33 0 miRanda -0.7 0.00034 NA
9 hsa-miR-590-3p ABCA8 2.59 0 -5.33 0 miRanda -0.89 0 NA
10 hsa-miR-590-3p ABCA9 2.59 0 -3.14 0 miRanda -0.71 0 NA
11 hsa-miR-590-3p ABCB1 2.59 0 -2.33 0 miRanda -0.29 1.0E-5 NA
12 hsa-miR-590-3p ABCB4 2.59 0 -1.92 0 miRanda -0.4 0 NA
13 hsa-miR-590-3p ABCC4 2.59 0 -1.54 1.0E-5 mirMAP -0.25 2.0E-5 NA
14 hsa-miR-193a-5p ABCC5 0.56 0.02393 0.08 0.78106 PITA -0.35 0 NA
15 hsa-miR-342-3p ABCC9 1.49 0 -2.76 0 miRanda -0.21 0.00234 NA
16 hsa-miR-590-3p ABCC9 2.59 0 -2.76 0 miRanda; mirMAP -0.64 0 NA
17 hsa-miR-361-5p ABCD2 0.97 0 -3.08 0 miRanda -1.28 0 NA
18 hsa-miR-590-3p ABCD2 2.59 0 -3.08 0 MirTarget; miRanda; mirMAP -0.35 3.0E-5 NA
19 hsa-miR-454-3p ABHD2 2.47 0 -0.37 0.12248 mirMAP -0.13 0.00468 NA
20 hsa-miR-590-3p ABHD2 2.59 0 -0.37 0.12248 miRanda; mirMAP -0.15 0.00026 NA
21 hsa-miR-342-3p ABI2 1.49 0 -0.65 0 miRanda -0.1 0 NA
22 hsa-miR-590-3p ABI2 2.59 0 -0.65 0 miRanda; mirMAP -0.11 0 NA
23 hsa-miR-590-3p ABI3BP 2.59 0 -4.28 0 miRanda -0.81 0 NA
24 hsa-miR-664a-3p ABI3BP 0.63 0.0052 -4.28 0 mirMAP -0.28 0.01097 NA
25 hsa-miR-26a-2-3p ABL1 0.82 0.00017 -1.32 0 mirMAP -0.15 1.0E-5 NA
26 hsa-miR-361-5p ABL1 0.97 0 -1.32 0 miRanda -0.32 0 NA
27 hsa-miR-361-5p ABL2 0.97 0 -0.32 0.04554 mirMAP -0.15 0.00146 NA
28 hsa-miR-590-3p ABLIM1 2.59 0 -1.72 0 miRanda; mirMAP -0.17 0.0006 NA
29 hsa-miR-362-5p ABR 1.59 0 -0.82 1.0E-5 TargetScan -0.1 0.00053 NA
30 hsa-miR-361-5p ACACB 0.97 0 -2.93 0 miRanda -0.48 0 NA
31 hsa-miR-24-2-5p ACADSB 2.07 0 -1 0.00017 MirTarget -0.34 0 NA
32 hsa-miR-590-3p ACADSB 2.59 0 -1 0.00017 MirTarget; miRanda; mirMAP -0.19 5.0E-5 NA
33 hsa-miR-664a-3p ACAN 0.63 0.0052 0.96 0.02146 mirMAP -0.47 0 NA
34 hsa-miR-590-3p ACAT1 2.59 0 -1.05 0 mirMAP -0.13 0.00058 NA
35 hsa-miR-193a-5p ACBD4 0.56 0.02393 -0.26 0.28006 MirTarget -0.25 0 NA
36 hsa-miR-664a-3p ACER3 0.63 0.0052 -0.12 0.46232 mirMAP -0.14 8.0E-5 NA
37 hsa-miR-590-3p ACOT1 2.59 0 -0.69 0.00048 miRanda -0.21 0 NA
38 hsa-miR-590-3p ACOT2 2.59 0 -0.56 0.00263 miRanda -0.17 0 NA
39 hsa-miR-590-3p ACOX2 2.59 0 -3.75 0 miRanda -0.71 0 NA
40 hsa-miR-26a-2-3p ACSBG1 0.82 0.00017 -0.87 0.10903 MirTarget -0.27 0.02296 NA
41 hsa-miR-454-3p ACSL1 2.47 0 -0 0.993 MirTarget -0.11 0.01806 NA
42 hsa-miR-181d-5p ACSS3 1.52 0 -2.48 1.0E-5 MirTarget -0.2 0.03508 NA
43 hsa-miR-590-3p ACSS3 2.59 0 -2.48 1.0E-5 miRanda -0.58 0 NA
44 hsa-miR-1307-3p ACTB 2.76 0 -0.54 0.00046 miRNAWalker2 validate -0.17 0 NA
45 hsa-miR-590-3p ACTB 2.59 0 -0.54 0.00046 miRanda -0.1 0.00016 NA
46 hsa-miR-361-5p ACTC1 0.97 0 -7.19 0 miRanda; miRNATAP -3.21 0 NA
47 hsa-miR-590-3p ACTC1 2.59 0 -7.19 0 miRanda -1.76 0 NA
48 hsa-miR-590-3p ACTG2 2.59 0 -5.39 0 miRanda -1.27 0 NA
49 hsa-miR-532-3p ACTN1 1.97 0 -1.05 0.00011 miRNATAP -0.42 0 NA
50 hsa-miR-590-3p ACTN1 2.59 0 -1.05 0.00011 miRanda; miRNATAP -0.33 0 NA
51 hsa-miR-361-5p ACTN4 0.97 0 -0.06 0.65476 miRanda -0.18 1.0E-5 NA
52 hsa-miR-362-5p ACTR3 1.59 0 -0.05 0.71644 TargetScan -0.1 0 NA
53 hsa-miR-454-3p ACVR1 2.47 0 -0.44 0.01143 MirTarget; miRNATAP -0.25 0 NA
54 hsa-miR-590-3p ACVR1 2.59 0 -0.44 0.01143 miRanda -0.2 0 NA
55 hsa-miR-214-3p ACVR1B -0.18 0.64249 0.35 0.04863 MirTarget -0.13 0 NA
56 hsa-miR-342-3p ACVR1B 1.49 0 0.35 0.04863 MirTarget; PITA; mirMAP -0.12 7.0E-5 NA
57 hsa-miR-361-5p ADAM12 0.97 0 0.88 0.05623 miRanda -0.82 0 NA
58 hsa-miR-454-3p ADAM12 2.47 0 0.88 0.05623 miRNATAP -0.41 0 NA
59 hsa-miR-590-3p ADAM12 2.59 0 0.88 0.05623 mirMAP -0.23 0.00464 NA
60 hsa-miR-361-5p ADAM19 0.97 0 -1.06 0.01895 miRanda -1.17 0 NA
61 hsa-miR-590-3p ADAM19 2.59 0 -1.06 0.01895 miRanda -0.23 0.00353 NA
62 hsa-miR-664a-3p ADAM19 0.63 0.0052 -1.06 0.01895 MirTarget -0.88 0 NA
63 hsa-miR-361-5p ADAM28 0.97 0 -0.73 0.15943 mirMAP -0.49 0.00113 NA
64 hsa-miR-590-3p ADAM32 2.59 0 -0.49 0.23688 miRanda -0.16 0.0295 NA
65 hsa-miR-590-3p ADAM33 2.59 0 -4.48 0 miRanda -0.8 0 NA
66 hsa-miR-342-3p ADAM9 1.49 0 -0.2 0.40665 miRanda -0.14 0.00088 NA
67 hsa-miR-590-3p ADAM9 2.59 0 -0.2 0.40665 miRanda; mirMAP -0.17 4.0E-5 NA
68 hsa-miR-342-3p ADAMTS1 1.49 0 -3.81 0 miRanda -0.33 0 NA
69 hsa-miR-590-3p ADAMTS1 2.59 0 -3.81 0 miRanda -0.59 0 NA
70 hsa-miR-362-5p ADAMTS12 1.59 0 0.14 0.80728 mirMAP -0.21 0.02341 NA
71 hsa-miR-214-3p ADAMTS13 -0.18 0.64249 -0.18 0.57737 mirMAP -0.14 0.00096 NA
72 hsa-miR-590-3p ADAMTS14 2.59 0 0.61 0.12479 miRanda -0.14 0.03948 NA
73 hsa-miR-342-3p ADAMTS15 1.49 0 -2.81 0 mirMAP -0.26 0.01284 NA
74 hsa-miR-590-3p ADAMTS16 2.59 0 -1.54 0.01905 miRanda; mirMAP -0.77 0 NA
75 hsa-miR-590-3p ADAMTS17 2.59 0 -1.24 0.00463 miRanda -0.2 0.01117 NA
76 hsa-miR-454-3p ADAMTS18 2.47 0 -0.74 0.14599 miRNATAP -0.48 0 NA
77 hsa-miR-590-3p ADAMTS18 2.59 0 -0.74 0.14599 PITA; miRanda; miRNATAP -0.43 0 NA
78 hsa-miR-342-3p ADAMTS19 1.49 0 -2.99 0 miRanda -0.35 0.00095 NA
79 hsa-miR-532-3p ADAMTS2 1.97 0 -0.77 0.15763 mirMAP -0.54 0 NA
80 hsa-miR-590-3p ADAMTS3 2.59 0 -1.18 0.00448 miRanda; mirMAP -0.21 0.00422 NA
81 hsa-miR-361-5p ADAMTS5 0.97 0 -2.16 0 PITA; miRanda -0.64 0 NA
82 hsa-miR-590-3p ADAMTS5 2.59 0 -2.16 0 PITA; miRanda; miRNATAP -0.4 0 NA
83 hsa-miR-664a-3p ADAMTS5 0.63 0.0052 -2.16 0 mirMAP -0.28 7.0E-5 NA
84 hsa-miR-590-3p ADAMTS6 2.59 0 -0.88 0.01914 miRanda -0.27 6.0E-5 NA
85 hsa-miR-664a-3p ADAMTS6 0.63 0.0052 -0.88 0.01914 mirMAP -0.63 0 NA
86 hsa-miR-342-3p ADAMTS8 1.49 0 -4.33 0 miRanda -0.44 0 NA
87 hsa-miR-590-3p ADAMTS8 2.59 0 -4.33 0 miRanda -0.94 0 NA
88 hsa-miR-590-3p ADAMTS9 2.59 0 -1.79 0 miRanda -0.36 0 NA
89 hsa-miR-590-3p ADAMTSL1 2.59 0 -2.52 0 miRanda; mirMAP -0.49 0 NA
90 hsa-miR-664a-3p ADAMTSL1 0.63 0.0052 -2.52 0 mirMAP -0.43 1.0E-5 NA
91 hsa-miR-590-3p ADAMTSL3 2.59 0 -5.11 0 miRanda -0.92 0 NA
92 hsa-miR-590-3p ADAMTSL5 2.59 0 -0.41 0.32739 miRanda -0.15 0.03422 NA
93 hsa-miR-664a-3p ADAP2 0.63 0.0052 0.02 0.93649 mirMAP -0.33 0 NA
94 hsa-miR-181d-5p ADARB1 1.52 0 -1.93 0 MirTarget -0.26 0 NA
95 hsa-miR-590-3p ADARB1 2.59 0 -1.93 0 miRanda; mirMAP -0.44 0 NA
96 hsa-miR-27a-5p ADCY1 0.05 0.86909 -0.16 0.70518 MirTarget -0.24 0.00012 NA
97 hsa-miR-342-3p ADCY2 1.49 0 -3.87 0 miRanda -0.2 0.04424 NA
98 hsa-miR-361-5p ADCY2 0.97 0 -3.87 0 MirTarget; PITA; miRanda; miRNATAP -1.04 0 NA
99 hsa-miR-454-3p ADCY2 2.47 0 -3.87 0 miRNATAP -0.72 0 NA
100 hsa-miR-590-3p ADCY2 2.59 0 -3.87 0 mirMAP -0.75 0 NA
101 hsa-miR-361-5p ADCY9 0.97 0 -1.5 0 miRanda -0.65 0 NA
102 hsa-miR-590-3p ADCY9 2.59 0 -1.5 0 miRanda -0.26 0 NA
103 hsa-miR-361-5p ADCYAP1 0.97 0 -3.51 0 miRanda -0.98 0 NA
104 hsa-miR-590-3p ADCYAP1 2.59 0 -3.51 0 MirTarget; PITA; miRanda; miRNATAP -0.71 0 NA
105 hsa-miR-590-3p ADD1 2.59 0 -0.81 0 MirTarget; PITA; miRanda; miRNATAP -0.14 0 NA
106 hsa-miR-365a-3p ADD3 -0.04 0.85911 -0.66 0.00185 MirTarget; miRNATAP -0.15 0.00173 NA
107 hsa-miR-590-3p ADH1A 2.59 0 -4.53 0 miRanda -0.6 0 NA
108 hsa-miR-590-3p ADH1B 2.59 0 -7.89 0 miRanda; mirMAP -1.26 0 NA
109 hsa-miR-590-3p ADH1C 2.59 0 -3.38 7.0E-5 miRanda -0.46 0.00247 NA
110 hsa-let-7i-3p ADHFE1 0.87 0.0008 -2.28 0 MirTarget -0.54 0 NA
111 hsa-miR-342-3p ADHFE1 1.49 0 -2.28 0 miRanda -0.26 0.00091 NA
112 hsa-miR-362-5p ADHFE1 1.59 0 -2.28 0 TargetScan; miRNATAP -0.26 0.00047 NA
113 hsa-miR-590-3p ADIPOQ 2.59 0 -5.02 0 PITA; miRanda; mirMAP -1.12 0 NA
114 hsa-miR-181d-5p ADM 1.52 0 -0.13 0.70322 MirTarget -0.25 2.0E-5 NA
115 hsa-miR-361-5p ADORA1 0.97 0 0.39 0.31104 miRanda -0.57 0 NA
116 hsa-miR-361-5p ADRA2A 0.97 0 -2.58 0 miRanda -0.88 0 NA
117 hsa-miR-362-5p AFAP1 1.59 0 -0.98 0.00012 mirMAP -0.16 7.0E-5 NA
118 hsa-miR-590-3p AFAP1 2.59 0 -0.98 0.00012 PITA; miRanda; miRNATAP -0.22 0 NA
119 hsa-miR-664a-3p AFAP1 0.63 0.0052 -0.98 0.00012 mirMAP -0.47 0 NA
120 hsa-miR-214-5p AFF1 0.96 0.00691 -0.53 0.00163 miRNATAP -0.14 0 NA
121 hsa-miR-26a-2-3p AFF1 0.82 0.00017 -0.53 0.00163 mirMAP -0.14 0.00016 NA
122 hsa-miR-369-3p AFF1 0.95 0.00135 -0.53 0.00163 PITA -0.11 6.0E-5 NA
123 hsa-miR-342-3p AFF2 1.49 0 -1.73 0.00201 mirMAP -0.24 0.01228 NA
124 hsa-miR-532-3p AFF2 1.97 0 -1.73 0.00201 miRNATAP -0.3 0.00205 NA
125 hsa-miR-590-3p AFF2 2.59 0 -1.73 0.00201 PITA; miRanda; mirMAP; miRNATAP -0.25 0.01122 NA
126 hsa-miR-193a-5p AFF3 0.56 0.02393 -5 0 miRNATAP -0.28 0.00783 NA
127 hsa-miR-590-3p AFF3 2.59 0 -5 0 PITA; miRanda; mirMAP; miRNATAP -0.79 0 NA
128 hsa-miR-361-5p AFF4 0.97 0 -0.82 0 miRanda -0.1 0.02408 NA
129 hsa-miR-590-3p AFF4 2.59 0 -0.82 0 MirTarget; PITA; miRanda; mirMAP; miRNATAP -0.11 2.0E-5 NA
130 hsa-miR-342-3p AGAP1 1.49 0 -0.4 0.01021 miRanda -0.17 0 NA
131 hsa-miR-342-3p AGAP11 1.49 0 -0.01 0.97979 miRanda -0.28 0.00389 NA
132 hsa-miR-193a-5p AGAP3 0.56 0.02393 0.42 0.01212 miRNATAP -0.18 0 NA
133 hsa-miR-181d-5p AGFG1 1.52 0 -0.17 0.30925 MirTarget -0.16 0 NA
134 hsa-miR-454-3p AGFG1 2.47 0 -0.17 0.30925 MirTarget; miRNATAP -0.1 0.00083 NA
135 hsa-miR-664a-3p AGFG1 0.63 0.0052 -0.17 0.30925 MirTarget; mirMAP -0.21 0 NA
136 hsa-miR-590-3p AGL 2.59 0 -0.67 6.0E-5 PITA; miRanda; mirMAP; miRNATAP -0.12 6.0E-5 NA
137 hsa-miR-362-5p AGPAT4 1.59 0 -0.79 0.01174 mirMAP -0.21 4.0E-5 NA
138 hsa-miR-454-3p AGPAT4 2.47 0 -0.79 0.01174 mirMAP -0.27 0 NA
139 hsa-miR-361-5p AGPS 0.97 0 -0.1 0.48101 miRanda; miRNATAP -0.13 0.00105 NA
140 hsa-miR-664a-3p AGPS 0.63 0.0052 -0.1 0.48101 mirMAP -0.2 0 NA
141 hsa-miR-590-3p AGT 2.59 0 -1.62 0.00168 miRanda -0.31 0.0007 NA
142 hsa-miR-664a-3p AGTPBP1 0.63 0.0052 -0.1 0.57308 mirMAP -0.2 0 NA
143 hsa-miR-590-3p AGTR1 2.59 0 -4.49 0 miRanda -1.09 0 NA
144 hsa-miR-361-5p AHNAK 0.97 0 -1.66 0 miRanda -0.55 0 NA
145 hsa-miR-590-3p AHNAK 2.59 0 -1.66 0 miRanda -0.32 0 NA
146 hsa-miR-361-5p AIDA 0.97 0 -0.31 0.01307 miRanda -0.22 0 NA
147 hsa-miR-361-5p AJAP1 0.97 0 -1.65 0.0004 miRanda -0.38 0.0057 NA
148 hsa-miR-590-3p AK5 2.59 0 -1.18 0.03248 miRanda; mirMAP -0.21 0.02614 NA
149 hsa-miR-664a-3p AK7 0.63 0.0052 -0.6 0.15285 mirMAP -0.24 0.00648 NA
150 hsa-miR-342-3p AKAP11 1.49 0 -0.8 0 miRanda -0.19 0 NA
NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF CELL DIFFERENTIATION 465 1492 2.2e-49 1.024e-45
2 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 501 1672 8.095e-48 1.883e-44
3 NEUROGENESIS 439 1402 4.409e-47 6.838e-44
4 CARDIOVASCULAR SYSTEM DEVELOPMENT 283 788 4.169e-42 3.88e-39
5 CIRCULATORY SYSTEM DEVELOPMENT 283 788 4.169e-42 3.88e-39
6 TISSUE DEVELOPMENT 451 1518 9.899e-42 7.677e-39
7 CELL DEVELOPMENT 429 1426 4.426e-41 2.942e-38
8 REGULATION OF CELLULAR COMPONENT MOVEMENT 272 771 7.322e-39 4.259e-36
9 BIOLOGICAL ADHESION 329 1032 1.043e-36 5.395e-34
10 REGULATION OF CELL DEVELOPMENT 280 836 2.238e-35 1.041e-32
11 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 322 1021 6.622e-35 2.801e-32
12 VASCULATURE DEVELOPMENT 187 469 8.574e-35 3.325e-32
13 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 349 1142 9.623e-35 3.444e-32
14 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 404 1395 1.845e-34 6.132e-32
15 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 458 1656 7.273e-34 2.256e-31
16 RESPONSE TO ENDOGENOUS STIMULUS 412 1450 3.937e-33 1.145e-30
17 NEURON DIFFERENTIATION 279 874 3.201e-31 8.762e-29
18 POSITIVE REGULATION OF MOLECULAR FUNCTION 474 1791 4.179e-30 1.08e-27
19 BLOOD VESSEL MORPHOGENESIS 150 364 6.194e-30 1.517e-27
20 INTRACELLULAR SIGNAL TRANSDUCTION 427 1572 1.282e-29 2.984e-27
21 POSITIVE REGULATION OF RESPONSE TO STIMULUS 500 1929 1.821e-29 3.7e-27
22 ORGAN MORPHOGENESIS 267 841 1.829e-29 3.7e-27
23 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 305 1008 1.702e-29 3.7e-27
24 POSITIVE REGULATION OF CELL DIFFERENTIATION 261 823 9.969e-29 1.933e-26
25 POSITIVE REGULATION OF CELL COMMUNICATION 415 1532 1.713e-28 3.189e-26
26 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 359 1275 5.764e-28 1.032e-25
27 LOCOMOTION 324 1114 6.617e-28 1.14e-25
28 CENTRAL NERVOUS SYSTEM DEVELOPMENT 270 872 7.302e-28 1.213e-25
29 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 241 750 1.734e-27 2.783e-25
30 REGULATION OF NEURON DIFFERENTIATION 194 554 2.147e-27 3.33e-25
31 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 287 957 4.54e-27 6.814e-25
32 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 374 1360 5.621e-27 8.174e-25
33 REGULATION OF PHOSPHORUS METABOLIC PROCESS 427 1618 9.675e-27 1.364e-24
34 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 249 801 5.204e-26 7.122e-24
35 REGULATION OF CELL PROLIFERATION 399 1496 6.423e-26 8.539e-24
36 NEGATIVE REGULATION OF CELL COMMUNICATION 333 1192 2.77e-25 3.58e-23
37 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 179 513 3.838e-25 4.827e-23
38 REGULATION OF TRANSPORT 459 1804 4.397e-25 5.384e-23
39 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 245 799 1.151e-24 1.373e-22
40 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 466 1848 1.38e-24 1.605e-22
41 TUBE DEVELOPMENT 187 552 1.752e-24 1.988e-22
42 RESPONSE TO OXYGEN CONTAINING COMPOUND 370 1381 2.11e-24 2.337e-22
43 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 219 689 2.394e-24 2.574e-22
44 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 285 983 2.434e-24 2.574e-22
45 MUSCLE STRUCTURE DEVELOPMENT 157 432 2.868e-24 2.966e-22
46 EPITHELIUM DEVELOPMENT 276 945 4.136e-24 4.135e-22
47 HEAD DEVELOPMENT 223 709 4.177e-24 4.135e-22
48 HEART DEVELOPMENT 165 466 4.91e-24 4.76e-22
49 POSITIVE REGULATION OF CATALYTIC ACTIVITY 397 1518 5.129e-24 4.87e-22
50 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 295 1036 7.952e-24 7.255e-22
51 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 295 1036 7.952e-24 7.255e-22
52 CELL MOTILITY 250 835 1.57e-23 1.379e-21
53 LOCALIZATION OF CELL 250 835 1.57e-23 1.379e-21
54 CELLULAR COMPONENT MORPHOGENESIS 263 900 4.897e-23 4.219e-21
55 REGULATION OF CELL PROJECTION ORGANIZATION 185 558 5.194e-23 4.394e-21
56 SKELETAL SYSTEM DEVELOPMENT 160 455 5.524e-23 4.59e-21
57 NEURON DEVELOPMENT 215 687 5.786e-23 4.723e-21
58 REGULATION OF NEURON PROJECTION DEVELOPMENT 148 408 7.515e-23 6.029e-21
59 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 257 876 8.65e-23 6.822e-21
60 REGULATION OF SYSTEM PROCESS 172 507 1.123e-22 8.707e-21
61 REGULATION OF PROTEIN MODIFICATION PROCESS 430 1710 2.178e-22 1.661e-20
62 NEURON PROJECTION DEVELOPMENT 180 545 3.292e-22 2.471e-20
63 POSITIVE REGULATION OF TRANSPORT 268 936 4.607e-22 3.402e-20
64 REGULATION OF CELL MORPHOGENESIS 181 552 6.184e-22 4.496e-20
65 REGULATION OF MAPK CASCADE 205 660 1.672e-21 1.197e-19
66 PROTEIN PHOSPHORYLATION 268 944 1.722e-21 1.214e-19
67 REGULATION OF ION TRANSPORT 189 592 2.233e-21 1.551e-19
68 ANGIOGENESIS 115 293 3.622e-21 2.461e-19
69 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 440 1784 3.649e-21 2.461e-19
70 POSITIVE REGULATION OF CELL DEVELOPMENT 160 472 3.929e-21 2.611e-19
71 NEGATIVE REGULATION OF CELL DIFFERENTIATION 192 609 5.218e-21 3.42e-19
72 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 126 337 6.37e-21 4.117e-19
73 TISSUE MORPHOGENESIS 174 533 6.711e-21 4.278e-19
74 RESPONSE TO WOUNDING 181 563 6.977e-21 4.387e-19
75 RESPONSE TO HORMONE 254 893 1.599e-20 9.918e-19
76 POSITIVE REGULATION OF GENE EXPRESSION 427 1733 1.909e-20 1.169e-18
77 CELL PROJECTION ORGANIZATION 255 902 3.254e-20 1.966e-18
78 REGULATION OF HYDROLASE ACTIVITY 344 1327 3.834e-20 2.287e-18
79 POSITIVE REGULATION OF LOCOMOTION 145 420 4.337e-20 2.554e-18
80 POSITIVE REGULATION OF HYDROLASE ACTIVITY 255 905 5.266e-20 3.063e-18
81 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 377 1492 5.388e-20 3.095e-18
82 POSITIVE REGULATION OF MAPK CASCADE 156 470 1.251e-19 7.1e-18
83 EMBRYO DEVELOPMENT 251 894 1.754e-19 9.834e-18
84 REGULATION OF GTPASE ACTIVITY 201 673 5.933e-19 3.286e-17
85 REGULATION OF MEMBRANE POTENTIAL 123 343 9.816e-19 5.373e-17
86 REGULATION OF KINASE ACTIVITY 223 776 1.075e-18 5.819e-17
87 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 299 1135 1.262e-18 6.748e-17
88 NEURON PROJECTION MORPHOGENESIS 137 402 1.705e-18 9.017e-17
89 REGULATION OF CELL DEATH 367 1472 1.867e-18 9.762e-17
90 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 271 1004 1.948e-18 1.007e-16
91 REGULATION OF BLOOD CIRCULATION 110 295 2.484e-18 1.27e-16
92 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 145 437 2.571e-18 1.273e-16
93 RESPONSE TO GROWTH FACTOR 154 475 2.568e-18 1.273e-16
94 UROGENITAL SYSTEM DEVELOPMENT 111 299 2.557e-18 1.273e-16
95 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 432 1805 3.106e-18 1.521e-16
96 REGULATION OF METAL ION TRANSPORT 117 325 4.918e-18 2.384e-16
97 RESPONSE TO LIPID 245 888 5.288e-18 2.537e-16
98 RESPONSE TO ORGANIC CYCLIC COMPOUND 251 917 5.957e-18 2.828e-16
99 POSITIVE REGULATION OF NEURON DIFFERENTIATION 112 306 6.163e-18 2.897e-16
100 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 300 1152 6.353e-18 2.956e-16
101 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 168 541 8.371e-18 3.819e-16
102 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 168 541 8.371e-18 3.819e-16
103 REGULATION OF HEART CONTRACTION 89 221 1.602e-17 7.238e-16
104 BEHAVIOR 160 516 6.022e-17 2.694e-15
105 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 125 368 7.347e-17 3.256e-15
106 CONNECTIVE TISSUE DEVELOPMENT 80 194 1.346e-16 5.909e-15
107 RESPONSE TO NITROGEN COMPOUND 234 859 1.56e-16 6.729e-15
108 MUSCLE SYSTEM PROCESS 103 282 1.562e-16 6.729e-15
109 EMBRYONIC MORPHOGENESIS 164 539 1.729e-16 7.38e-15
110 RESPONSE TO ABIOTIC STIMULUS 268 1024 2.215e-16 9.371e-15
111 EXTRACELLULAR STRUCTURE ORGANIZATION 108 304 2.769e-16 1.161e-14
112 TAXIS 146 464 3.586e-16 1.49e-14
113 CELLULAR RESPONSE TO HORMONE STIMULUS 166 552 3.755e-16 1.546e-14
114 POSITIVE REGULATION OF KINASE ACTIVITY 150 482 4.079e-16 1.665e-14
115 SINGLE ORGANISM BEHAVIOR 127 384 4.453e-16 1.802e-14
116 WOUND HEALING 147 470 5.033e-16 2.019e-14
117 CELL CELL ADHESION 178 608 5.571e-16 2.216e-14
118 TUBE MORPHOGENESIS 112 323 5.74e-16 2.263e-14
119 MUSCLE TISSUE DEVELOPMENT 100 275 6.055e-16 2.348e-14
120 POSITIVE REGULATION OF ION TRANSPORT 90 236 6.021e-16 2.348e-14
121 CIRCULATORY SYSTEM PROCESS 122 366 8.736e-16 3.36e-14
122 MORPHOGENESIS OF AN EPITHELIUM 130 400 9.415e-16 3.591e-14
123 NEGATIVE REGULATION OF PHOSPHORYLATION 135 422 1.093e-15 4.103e-14
124 PHOSPHORYLATION 307 1228 1.09e-15 4.103e-14
125 SENSORY ORGAN DEVELOPMENT 151 493 1.496e-15 5.57e-14
126 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 452 1977 2.394e-15 8.841e-14
127 MUSCLE CELL DIFFERENTIATION 89 237 2.601e-15 9.529e-14
128 POSITIVE REGULATION OF CELL PROLIFERATION 220 814 3.342e-15 1.215e-13
129 REGULATION OF CELL ADHESION 180 629 4.168e-15 1.503e-13
130 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 105 303 4.916e-15 1.76e-13
131 CELLULAR RESPONSE TO NITROGEN COMPOUND 152 505 6.264e-15 2.225e-13
132 EMBRYONIC ORGAN DEVELOPMENT 129 406 8.503e-15 2.997e-13
133 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 150 498 8.872e-15 3.104e-13
134 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 86 232 1.834e-14 6.37e-13
135 GROWTH 129 410 1.944e-14 6.699e-13
136 ACTIN FILAMENT BASED PROCESS 138 450 2.273e-14 7.778e-13
137 REGULATION OF EPITHELIAL CELL PROLIFERATION 99 285 2.49e-14 8.455e-13
138 REGULATION OF MUSCLE SYSTEM PROCESS 76 195 2.862e-14 9.65e-13
139 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 97 278 3.313e-14 1.109e-12
140 CELLULAR RESPONSE TO LIPID 139 457 3.737e-14 1.242e-12
141 RESPONSE TO EXTERNAL STIMULUS 416 1821 4.368e-14 1.441e-12
142 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 60 138 4.971e-14 1.629e-12
143 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 84 229 7.313e-14 2.38e-12
144 REGULATION OF TRANSMEMBRANE TRANSPORT 131 426 8.315e-14 2.687e-12
145 RESPONSE TO OXYGEN LEVELS 104 311 9.277e-14 2.977e-12
146 DEVELOPMENTAL GROWTH 109 333 1.177e-13 3.75e-12
147 NEGATIVE REGULATION OF LOCOMOTION 92 263 1.275e-13 4.035e-12
148 CELL ACTIVATION 162 568 1.392e-13 4.377e-12
149 MORPHOGENESIS OF A BRANCHING STRUCTURE 67 167 1.887e-13 5.893e-12
150 BONE DEVELOPMENT 64 156 1.927e-13 5.978e-12
151 SECOND MESSENGER MEDIATED SIGNALING 65 160 2.162e-13 6.661e-12
152 RESPONSE TO MECHANICAL STIMULUS 78 210 2.651e-13 8.115e-12
153 CELL PART MORPHOGENESIS 175 633 2.986e-13 9.082e-12
154 NEGATIVE REGULATION OF CELL PROLIFERATION 177 643 3.295e-13 9.954e-12
155 SENSORY ORGAN MORPHOGENESIS 85 239 3.816e-13 1.146e-11
156 CARTILAGE DEVELOPMENT 61 147 3.852e-13 1.149e-11
157 REGULATION OF CELLULAR LOCALIZATION 306 1277 4.029e-13 1.194e-11
158 FOREBRAIN DEVELOPMENT 113 357 5.238e-13 1.543e-11
159 MULTICELLULAR ORGANISMAL SIGNALING 54 123 5.59e-13 1.627e-11
160 RESPIRATORY SYSTEM DEVELOPMENT 74 197 5.595e-13 1.627e-11
161 POSITIVE REGULATION OF CELL DEATH 168 605 6.015e-13 1.738e-11
162 REGULATION OF TRANSFERASE ACTIVITY 239 946 6.352e-13 1.824e-11
163 SYNAPSE ORGANIZATION 60 145 6.942e-13 1.982e-11
164 REGULATION OF ACTIN FILAMENT BASED PROCESS 102 312 7.861e-13 2.23e-11
165 RESPONSE TO STEROID HORMONE 144 497 8.747e-13 2.467e-11
166 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 138 470 8.926e-13 2.502e-11
167 STRIATED MUSCLE CELL DIFFERENTIATION 67 173 1.338e-12 3.719e-11
168 REGULATION OF CELLULAR COMPONENT BIOGENESIS 201 767 1.343e-12 3.719e-11
169 REGULATION OF CATION TRANSMEMBRANE TRANSPORT 76 208 1.403e-12 3.862e-11
170 REGULATION OF MAP KINASE ACTIVITY 103 319 1.441e-12 3.943e-11
171 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 195 740 1.711e-12 4.655e-11
172 REGULATION OF BODY FLUID LEVELS 145 506 1.836e-12 4.967e-11
173 REGULATION OF VASCULATURE DEVELOPMENT 82 233 1.874e-12 5.041e-11
174 REGULATION OF GROWTH 172 633 2.377e-12 6.356e-11
175 NEGATIVE REGULATION OF TRANSPORT 134 458 2.539e-12 6.751e-11
176 REGULATION OF HEART RATE 42 86 2.776e-12 7.34e-11
177 EPITHELIAL CELL DIFFERENTIATION 142 495 2.861e-12 7.521e-11
178 COGNITION 86 251 2.902e-12 7.586e-11
179 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 129 437 3.294e-12 8.561e-11
180 MUSCLE ORGAN DEVELOPMENT 92 277 3.821e-12 9.878e-11
181 REGULATION OF HOMEOSTATIC PROCESS 131 447 3.93e-12 1.01e-10
182 NEGATIVE REGULATION OF CELL DEVELOPMENT 98 303 4.488e-12 1.147e-10
183 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 72 197 5.332e-12 1.356e-10
184 REGULATION OF ION HOMEOSTASIS 73 201 5.411e-12 1.368e-10
185 EMBRYONIC ORGAN MORPHOGENESIS 92 279 6.029e-12 1.516e-10
186 REGULATION OF OSSIFICATION 67 178 6.195e-12 1.55e-10
187 STEM CELL DIFFERENTIATION 70 190 6.799e-12 1.692e-10
188 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 134 465 8.329e-12 2.061e-10
189 MEMBRANE DEPOLARIZATION DURING CARDIAC MUSCLE CELL ACTION POTENTIAL 14 14 9.905e-12 2.439e-10
190 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 80 232 1.145e-11 2.803e-10
191 REGULATION OF EPITHELIAL CELL MIGRATION 63 166 1.735e-11 4.226e-10
192 NEGATIVE REGULATION OF CELL DEATH 218 872 2.02e-11 4.895e-10
193 IMMUNE SYSTEM DEVELOPMENT 158 582 2.043e-11 4.925e-10
194 MESENCHYME DEVELOPMENT 69 190 2.056e-11 4.932e-10
195 REGULATION OF TRANSPORTER ACTIVITY 71 198 2.09e-11 4.987e-10
196 HEMOSTASIS 98 311 2.424e-11 5.755e-10
197 CELLULAR RESPONSE TO ACID CHEMICAL 65 175 2.515e-11 5.939e-10
198 SINGLE ORGANISM CELL ADHESION 131 459 2.951e-11 6.936e-10
199 VASCULOGENESIS 32 59 3.107e-11 7.265e-10
200 MUSCLE CONTRACTION 79 233 3.987e-11 9.276e-10
201 REGULATION OF CELL SUBSTRATE ADHESION 64 173 4.359e-11 1.009e-09
202 CHEMICAL HOMEOSTASIS 217 874 4.461e-11 1.028e-09
203 NEURON PROJECTION GUIDANCE 72 205 4.603e-11 1.055e-09
204 REGULATION OF PROTEIN LOCALIZATION 232 950 5.11e-11 1.166e-09
205 REGULATION OF DEVELOPMENTAL GROWTH 92 289 5.322e-11 1.208e-09
206 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 62 166 5.491e-11 1.24e-09
207 REGULATION OF RESPONSE TO WOUNDING 120 413 5.782e-11 1.3e-09
208 REGULATION OF MUSCLE CONTRACTION 57 147 5.848e-11 1.308e-09
209 POSITIVE REGULATION OF ENDOCYTOSIS 48 114 6.502e-11 1.448e-09
210 CYTOSKELETON ORGANIZATION 209 838 6.733e-11 1.492e-09
211 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 56 144 7.516e-11 1.658e-09
212 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 72 207 7.68e-11 1.686e-09
213 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 150 554 8.19e-11 1.789e-09
214 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 163 616 8.512e-11 1.851e-09
215 CELL CELL SIGNALING 194 767 9.431e-11 2.041e-09
216 REGULATION OF HEART RATE BY CARDIAC CONDUCTION 21 30 9.569e-11 2.061e-09
217 ACTIVATION OF PROTEIN KINASE ACTIVITY 89 279 9.679e-11 2.075e-09
218 MESENCHYMAL CELL DIFFERENTIATION 53 134 1.146e-10 2.446e-09
219 REGULATION OF RESPONSE TO STRESS 331 1468 1.262e-10 2.682e-09
220 REGULATION OF CALCIUM ION TRANSPORT 72 209 1.268e-10 2.683e-09
221 IMMUNE SYSTEM PROCESS 428 1984 1.285e-10 2.704e-09
222 RHYTHMIC PROCESS 93 298 1.391e-10 2.915e-09
223 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 162 616 1.61e-10 3.36e-09
224 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 225 926 1.669e-10 3.466e-09
225 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 32 62 1.734e-10 3.586e-09
226 TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 67 190 1.758e-10 3.62e-09
227 EYE DEVELOPMENT 99 326 1.96e-10 4.018e-09
228 CARDIAC CONDUCTION 38 82 2.144e-10 4.376e-09
229 REGULATION OF CYTOPLASMIC TRANSPORT 133 481 2.175e-10 4.419e-09
230 TELENCEPHALON DEVELOPMENT 76 228 2.306e-10 4.664e-09
231 CARDIAC MUSCLE TISSUE DEVELOPMENT 54 140 2.336e-10 4.706e-09
232 LEUKOCYTE DIFFERENTIATION 91 292 2.376e-10 4.765e-09
233 HEART MORPHOGENESIS 72 212 2.643e-10 5.278e-09
234 GLAND DEVELOPMENT 114 395 2.722e-10 5.413e-09
235 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 65 184 3.003e-10 5.946e-09
236 REGULATION OF SECRETION 178 699 3.247e-10 6.402e-09
237 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 104 352 3.908e-10 7.672e-09
238 ACTION POTENTIAL 41 94 4.295e-10 8.397e-09
239 HOMEOSTATIC PROCESS 303 1337 4.689e-10 9.129e-09
240 EPITHELIAL CELL DEVELOPMENT 65 186 5.04e-10 9.731e-09
241 PEPTIDYL TYROSINE MODIFICATION 65 186 5.04e-10 9.731e-09
242 CARDIAC MUSCLE CELL DIFFERENTIATION 35 74 5.486e-10 1.055e-08
243 MEMBRANE DEPOLARIZATION 31 61 5.53e-10 1.059e-08
244 REGULATION OF INTRACELLULAR TRANSPORT 161 621 5.739e-10 1.094e-08
245 REGULATION OF ENDOCYTOSIS 68 199 6.106e-10 1.16e-08
246 REGULATION OF JNK CASCADE 58 159 6.557e-10 1.24e-08
247 REGULATION OF VESICLE MEDIATED TRANSPORT 127 462 8.307e-10 1.565e-08
248 REGULATION OF CHEMOTAXIS 63 180 8.623e-10 1.618e-08
249 CARDIOCYTE DIFFERENTIATION 41 96 9.359e-10 1.749e-08
250 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 42 100 1.093e-09 2.034e-08
251 LUNG ALVEOLUS DEVELOPMENT 24 41 1.122e-09 2.081e-08
252 NEPHRON DEVELOPMENT 46 115 1.231e-09 2.273e-08
253 MODULATION OF SYNAPTIC TRANSMISSION 91 301 1.35e-09 2.482e-08
254 GLAND MORPHOGENESIS 41 97 1.366e-09 2.492e-08
255 REGULATION OF CARDIAC MUSCLE CONTRACTION 32 66 1.361e-09 2.492e-08
256 PLATELET ACTIVATION 53 142 1.372e-09 2.494e-08
257 CALCIUM MEDIATED SIGNALING 39 90 1.434e-09 2.585e-08
258 ENDOTHELIUM DEVELOPMENT 39 90 1.434e-09 2.585e-08
259 NEGATIVE REGULATION OF GENE EXPRESSION 330 1493 1.458e-09 2.62e-08
260 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 58 162 1.493e-09 2.673e-08
261 REGULATION OF OSTEOBLAST DIFFERENTIATION 45 112 1.568e-09 2.795e-08
262 LEUKOCYTE MIGRATION 81 259 1.892e-09 3.36e-08
263 MEMBRANE DEPOLARIZATION DURING ACTION POTENTIAL 23 39 2.039e-09 3.608e-08
264 POSITIVE REGULATION OF OSSIFICATION 37 84 2.162e-09 3.811e-08
265 CARDIAC CHAMBER DEVELOPMENT 53 144 2.446e-09 4.294e-08
266 CELL SUBSTRATE ADHESION 58 164 2.541e-09 4.429e-08
267 REGULATION OF PHOSPHOLIPASE ACTIVITY 31 64 2.532e-09 4.429e-08
268 SKELETAL SYSTEM MORPHOGENESIS 67 201 2.629e-09 4.564e-08
269 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 42 103 3.21e-09 5.552e-08
270 REGULATION OF ANATOMICAL STRUCTURE SIZE 127 472 3.508e-09 6.045e-08
271 CARDIAC MUSCLE CELL ACTION POTENTIAL 22 37 3.697e-09 6.347e-08
272 GLOMERULUS DEVELOPMENT 26 49 4.104e-09 6.994e-08
273 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 26 49 4.104e-09 6.994e-08
274 CARDIAC MUSCLE CELL CONTRACTION 19 29 4.289e-09 7.283e-08
275 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 55 154 4.346e-09 7.326e-08
276 AMEBOIDAL TYPE CELL MIGRATION 55 154 4.346e-09 7.326e-08
277 CELL PROLIFERATION 168 672 4.367e-09 7.335e-08
278 RESPONSE TO PEPTIDE 112 404 4.911e-09 8.19e-08
279 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 112 404 4.911e-09 8.19e-08
280 PATTERN SPECIFICATION PROCESS 115 418 4.934e-09 8.199e-08
281 REGULATION OF ERK1 AND ERK2 CASCADE 75 238 5.137e-09 8.506e-08
282 POSITIVE REGULATION OF TRANSMEMBRANE TRANSPORT 49 131 5.208e-09 8.563e-08
283 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 49 131 5.208e-09 8.563e-08
284 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 50 135 5.37e-09 8.798e-08
285 SYNAPSE ASSEMBLY 32 69 5.504e-09 8.985e-08
286 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 170 684 5.557e-09 9.041e-08
287 REGULATION OF CELL MATRIX ADHESION 38 90 5.612e-09 9.099e-08
288 RESPONSE TO ACID CHEMICAL 93 319 6.822e-09 1.095e-07
289 REGULATION OF WNT SIGNALING PATHWAY 91 310 6.828e-09 1.095e-07
290 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 249 1087 6.794e-09 1.095e-07
291 REGULATION OF STEM CELL DIFFERENTIATION 44 113 7.476e-09 1.195e-07
292 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 45 117 7.958e-09 1.268e-07
293 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 80 262 8.009e-09 1.272e-07
294 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 32 70 8.549e-09 1.353e-07
295 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 86 289 8.71e-09 1.374e-07
296 KIDNEY EPITHELIUM DEVELOPMENT 47 125 8.751e-09 1.376e-07
297 FAT CELL DIFFERENTIATION 42 106 8.886e-09 1.392e-07
298 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 49 133 9.3e-09 1.452e-07
299 RESPONSE TO ALCOHOL 102 362 9.446e-09 1.47e-07
300 NEURON MIGRATION 43 110 9.603e-09 1.489e-07
301 HOMOPHILIC CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 54 153 9.64e-09 1.49e-07
302 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 70 220 1.057e-08 1.629e-07
303 PLASMA MEMBRANE ORGANIZATION 66 203 1.064e-08 1.632e-07
304 NEGATIVE REGULATION OF IMMUNE SYSTEM PROCESS 104 372 1.066e-08 1.632e-07
305 REGULATION OF IMMUNE SYSTEM PROCESS 308 1403 1.13e-08 1.723e-07
306 REGULATION OF ORGAN MORPHOGENESIS 75 242 1.148e-08 1.746e-07
307 EAR DEVELOPMENT 64 195 1.172e-08 1.777e-07
308 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 63 191 1.226e-08 1.852e-07
309 CELL CELL ADHESION VIA PLASMA MEMBRANE ADHESION MOLECULES 66 204 1.324e-08 1.994e-07
310 REGULATION OF PROTEIN IMPORT 61 183 1.332e-08 1.999e-07
311 REGULATION OF PHOSPHOLIPASE C ACTIVITY 22 39 1.438e-08 2.151e-07
312 LEARNING 48 131 1.607e-08 2.397e-07
313 ACTIN FILAMENT BASED MOVEMENT 38 93 1.662e-08 2.47e-07
314 REPRODUCTIVE SYSTEM DEVELOPMENT 111 408 1.767e-08 2.618e-07
315 RESPONSE TO CORTICOSTEROID 59 176 1.812e-08 2.676e-07
316 REGULATION OF POSTSYNAPTIC MEMBRANE POTENTIAL 27 55 1.864e-08 2.745e-07
317 REGULATION OF AXONOGENESIS 57 168 1.934e-08 2.839e-07
318 REGULATION OF DENDRITE DEVELOPMENT 45 120 1.978e-08 2.894e-07
319 REGULATION OF MUSCLE CELL DIFFERENTIATION 53 152 2.114e-08 3.083e-07
320 NEGATIVE REGULATION OF KINASE ACTIVITY 76 250 2.312e-08 3.351e-07
321 REGULATION OF LIPASE ACTIVITY 35 83 2.31e-08 3.351e-07
322 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 110 406 2.602e-08 3.76e-07
323 CELL COMMUNICATION INVOLVED IN CARDIAC CONDUCTION 21 37 2.65e-08 3.817e-07
324 OSSIFICATION 76 251 2.79e-08 4.007e-07
325 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 327 1517 2.835e-08 4.059e-07
326 WNT SIGNALING PATHWAY 98 351 3.015e-08 4.304e-07
327 REGULATION OF PROTEIN SECRETION 106 389 3.366e-08 4.789e-07
328 POSITIVE REGULATION OF PHOSPHOLIPASE ACTIVITY 26 53 3.477e-08 4.932e-07
329 PROTEIN AUTOPHOSPHORYLATION 62 192 3.896e-08 5.511e-07
330 POSITIVE REGULATION OF CELL ADHESION 103 376 3.921e-08 5.529e-07
331 LEUKOCYTE ACTIVATION 111 414 4.128e-08 5.802e-07
332 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 28 60 4.147e-08 5.812e-07
333 CELL FATE COMMITMENT 70 227 4.355e-08 6.085e-07
334 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 72 236 4.565e-08 6.34e-07
335 NEGATIVE REGULATION OF GROWTH 72 236 4.565e-08 6.34e-07
336 HEART PROCESS 35 85 4.785e-08 6.627e-07
337 COLLAGEN FIBRIL ORGANIZATION 21 38 5.006e-08 6.912e-07
338 CELL JUNCTION ORGANIZATION 60 185 5.379e-08 7.405e-07
339 DIGESTIVE SYSTEM DEVELOPMENT 51 148 5.998e-08 8.209e-07
340 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 43 116 5.985e-08 8.209e-07
341 POSITIVE REGULATION OF MAP KINASE ACTIVITY 65 207 6.12e-08 8.35e-07
342 MUSCLE CELL DEVELOPMENT 46 128 6.271e-08 8.507e-07
343 EYE MORPHOGENESIS 48 136 6.258e-08 8.507e-07
344 APPENDAGE DEVELOPMENT 56 169 6.487e-08 8.749e-07
345 LIMB DEVELOPMENT 56 169 6.487e-08 8.749e-07
346 REGULATION OF CARDIAC MUSCLE CELL CONTRACTION 17 27 6.854e-08 9.217e-07
347 CELLULAR RESPONSE TO PEPTIDE 80 274 7.042e-08 9.443e-07
348 NEGATIVE REGULATION OF MOLECULAR FUNCTION 242 1079 7.504e-08 1.003e-06
349 REGULATION OF STRIATED MUSCLE CONTRACTION 33 79 7.596e-08 1.013e-06
350 REGULATION OF SYNAPSE ORGANIZATION 42 113 7.778e-08 1.034e-06
351 SECRETION BY CELL 125 486 7.864e-08 1.042e-06
352 ENDOTHELIAL CELL DIFFERENTIATION 31 72 8.124e-08 1.071e-06
353 NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 44 121 8.108e-08 1.071e-06
354 REGULATION OF CELL GROWTH 105 391 8.728e-08 1.147e-06
355 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 90 321 8.842e-08 1.159e-06
356 ION TRANSPORT 276 1262 9.899e-08 1.294e-06
357 REGULATION OF ENDOTHELIAL CELL MIGRATION 42 114 1.038e-07 1.353e-06
358 RESPONSE TO INORGANIC SUBSTANCE 123 479 1.098e-07 1.427e-06
359 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 148 602 1.118e-07 1.449e-06
360 MEMBRANE ASSEMBLY 16 25 1.208e-07 1.561e-06
361 SECRETION 145 588 1.234e-07 1.589e-06
362 POSITIVE REGULATION OF LIPASE ACTIVITY 29 66 1.236e-07 1.589e-06
363 REGULATION OF CHONDROCYTE DIFFERENTIATION 23 46 1.367e-07 1.752e-06
364 REGULATION OF SODIUM ION TRANSPORT 32 77 1.375e-07 1.756e-06
365 RESPONSE TO CALCIUM ION 42 115 1.378e-07 1.756e-06
366 SYSTEM PROCESS 372 1785 1.412e-07 1.795e-06
367 LOCOMOTORY BEHAVIOR 58 181 1.421e-07 1.802e-06
368 REGULATION OF MUSCLE ADAPTATION 28 63 1.513e-07 1.91e-06
369 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 79 274 1.514e-07 1.91e-06
370 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 52 156 1.522e-07 1.914e-06
371 REGULATION OF CELLULAR RESPONSE TO STRESS 165 691 1.656e-07 2.076e-06
372 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 39 104 1.703e-07 2.13e-06
373 FEMALE SEX DIFFERENTIATION 42 116 1.82e-07 2.27e-06
374 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 29 67 1.84e-07 2.277e-06
375 CHONDROCYTE DIFFERENTIATION 27 60 1.839e-07 2.277e-06
376 INOSITOL LIPID MEDIATED SIGNALING 44 124 1.831e-07 2.277e-06
377 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 65 213 1.996e-07 2.464e-06
378 REGULATION OF INFLAMMATORY RESPONSE 83 294 2.008e-07 2.471e-06
379 POSITIVE REGULATION OF CATION TRANSMEMBRANE TRANSPORT 37 97 2.115e-07 2.596e-06
380 CAMERA TYPE EYE MORPHOGENESIS 38 101 2.209e-07 2.705e-06
381 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 66 218 2.236e-07 2.73e-06
382 ODONTOGENESIS 39 105 2.283e-07 2.781e-06
383 CELL CHEMOTAXIS 53 162 2.297e-07 2.79e-06
384 REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 40 109 2.338e-07 2.833e-06
385 ARTERY DEVELOPMENT 31 75 2.487e-07 3.006e-06
386 REGULATION OF CELL JUNCTION ASSEMBLY 29 68 2.707e-07 3.255e-06
387 ORGAN GROWTH 29 68 2.707e-07 3.255e-06
388 PHOSPHATIDYLINOSITOL METABOLIC PROCESS 60 193 2.856e-07 3.425e-06
389 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 37 98 2.864e-07 3.426e-06
390 NEGATIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 38 102 2.968e-07 3.541e-06
391 REGULATED EXOCYTOSIS 67 224 2.99e-07 3.558e-06
392 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 20 38 3.051e-07 3.621e-06
393 POSITIVE REGULATION OF ERK1 AND ERK2 CASCADE 55 172 3.192e-07 3.764e-06
394 REGULATION OF ACTIN FILAMENT BASED MOVEMENT 18 32 3.189e-07 3.764e-06
395 REGULATION OF CELLULAR PROTEIN LOCALIZATION 136 552 3.195e-07 3.764e-06
396 ENSHEATHMENT OF NEURONS 35 91 3.531e-07 4.139e-06
397 AXON ENSHEATHMENT 35 91 3.531e-07 4.139e-06
398 POSITIVE REGULATION OF TRANSPORTER ACTIVITY 31 76 3.544e-07 4.144e-06
399 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORT 23 48 3.669e-07 4.279e-06
400 CELL GROWTH 46 135 3.794e-07 4.414e-06
401 REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 37 99 3.856e-07 4.463e-06
402 REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 37 99 3.856e-07 4.463e-06
403 CELL MATRIX ADHESION 42 119 4.077e-07 4.707e-06
404 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 50 152 4.136e-07 4.764e-06
405 FOREBRAIN CELL MIGRATION 27 62 4.166e-07 4.786e-06
406 SPROUTING ANGIOGENESIS 22 45 4.227e-07 4.845e-06
407 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 48 144 4.501e-07 5.146e-06
408 MULTI MULTICELLULAR ORGANISM PROCESS 64 213 4.564e-07 5.205e-06
409 REGULATION OF HEART GROWTH 21 42 4.784e-07 5.442e-06
410 REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 35 92 4.807e-07 5.455e-06
411 ION HOMEOSTASIS 140 576 4.947e-07 5.601e-06
412 DEVELOPMENTAL CELL GROWTH 31 77 5.006e-07 5.654e-06
413 PALLIUM DEVELOPMENT 50 153 5.175e-07 5.831e-06
414 CARDIAC CHAMBER MORPHOGENESIS 38 104 5.267e-07 5.92e-06
415 POSITIVE REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 20 39 5.297e-07 5.939e-06
416 EAR MORPHOGENESIS 40 112 5.351e-07 5.986e-06
417 POSITIVE REGULATION OF HEART GROWTH 16 27 5.532e-07 6.173e-06
418 MEMBRANE BIOGENESIS 17 30 5.908e-07 6.529e-06
419 SMOOTH MUSCLE CELL DIFFERENTIATION 17 30 5.908e-07 6.529e-06
420 POSITIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 17 30 5.908e-07 6.529e-06
421 CELLULAR RESPONSE TO VASCULAR ENDOTHELIAL GROWTH FACTOR STIMULUS 17 30 5.908e-07 6.529e-06
422 REGULATION OF CARTILAGE DEVELOPMENT 27 63 6.155e-07 6.787e-06
423 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 25 56 6.267e-07 6.894e-06
424 REGULATION OF DENDRITE MORPHOGENESIS 30 74 6.377e-07 6.998e-06
425 CELL JUNCTION ASSEMBLY 44 129 6.525e-07 7.144e-06
426 REGULATION OF RECEPTOR ACTIVITY 41 117 6.923e-07 7.562e-06
427 REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 28 67 7.158e-07 7.8e-06
428 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 26 60 7.64e-07 8.306e-06
429 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 64 216 7.861e-07 8.526e-06
430 SEX DIFFERENTIATION 75 266 8.029e-07 8.688e-06
431 PROTEIN LOCALIZATION TO CELL PERIPHERY 49 151 8.463e-07 9.118e-06
432 CELL CELL SIGNALING INVOLVED IN CARDIAC CONDUCTION 14 22 8.466e-07 9.118e-06
433 POSITIVE REGULATION OF SECRETION 97 370 8.763e-07 9.416e-06
434 PROTEIN LOCALIZATION 370 1805 8.874e-07 9.514e-06
435 REGULATION OF ADHERENS JUNCTION ORGANIZATION 23 50 9.147e-07 9.785e-06
436 CELL DEATH 221 1001 9.654e-07 1.03e-05
437 BONE MORPHOGENESIS 31 79 9.736e-07 1.037e-05
438 REGULATION OF BLOOD PRESSURE 53 169 1.02e-06 1.083e-05
439 NEGATIVE REGULATION OF ION TRANSPORT 43 127 1.09e-06 1.156e-05
440 MUSCLE HYPERTROPHY 16 28 1.094e-06 1.157e-05
441 LYMPHOCYTE DIFFERENTIATION 62 209 1.11e-06 1.171e-05
442 AGING 74 264 1.208e-06 1.272e-05
443 NEGATIVE REGULATION OF VASCULATURE DEVELOPMENT 31 80 1.341e-06 1.409e-05
444 NEURAL CREST CELL MIGRATION 23 51 1.408e-06 1.476e-05
445 NEGATIVE REGULATION OF DEVELOPMENTAL GROWTH 32 84 1.417e-06 1.481e-05
446 GLIOGENESIS 54 175 1.42e-06 1.481e-05
447 NEGATIVE REGULATION OF MAPK CASCADE 47 145 1.455e-06 1.515e-05
448 OVULATION CYCLE PROCESS 33 88 1.476e-06 1.533e-05
449 RESPONSE TO PURINE CONTAINING COMPOUND 50 158 1.516e-06 1.571e-05
450 INNER EAR MORPHOGENESIS 34 92 1.52e-06 1.571e-05
451 REGULATION OF CYTOSKELETON ORGANIZATION 123 502 1.563e-06 1.613e-05
452 CELL MIGRATION INVOLVED IN SPROUTING ANGIOGENESIS 11 15 1.619e-06 1.667e-05
453 REGULATION OF ACTION POTENTIAL 19 38 1.68e-06 1.726e-05
454 REGULATION OF KIDNEY DEVELOPMENT 24 55 1.734e-06 1.778e-05
455 REGULATION OF CELLULAR COMPONENT SIZE 89 337 1.752e-06 1.792e-05
456 CELLULAR RESPONSE TO INSULIN STIMULUS 47 146 1.808e-06 1.841e-05
457 LYMPHOCYTE ACTIVATION 90 342 1.806e-06 1.841e-05
458 METANEPHROS DEVELOPMENT 31 81 1.834e-06 1.857e-05
459 REGULATION OF CARDIAC MUSCLE CONTRACTION BY CALCIUM ION SIGNALING 14 23 1.836e-06 1.857e-05
460 REGULATION OF METANEPHROS DEVELOPMENT 14 23 1.836e-06 1.857e-05
461 REGULATION OF CARDIAC CONDUCTION 27 66 1.856e-06 1.873e-05
462 OVULATION CYCLE 39 113 1.978e-06 1.992e-05
463 NEPHRON EPITHELIUM DEVELOPMENT 34 93 2.021e-06 2.031e-05
464 CEREBRAL CORTEX DEVELOPMENT 37 105 2.038e-06 2.044e-05
465 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 80 296 2.202e-06 2.203e-05
466 ACTIN MEDIATED CELL CONTRACTION 29 74 2.227e-06 2.22e-05
467 DIVALENT INORGANIC CATION TRANSPORT 74 268 2.228e-06 2.22e-05
468 RESPONSE TO KETONE 55 182 2.341e-06 2.327e-05
469 CELLULAR RESPONSE TO OXYGEN LEVELS 46 143 2.371e-06 2.352e-05
470 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 63 218 2.423e-06 2.399e-05
471 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 61 209 2.438e-06 2.409e-05
472 VESICLE MEDIATED TRANSPORT 263 1239 2.572e-06 2.536e-05
473 CALCIUM ION TRANSPORT 64 223 2.616e-06 2.573e-05
474 POSITIVE REGULATION OF CALCIUM ION TRANSPORT 37 106 2.641e-06 2.576e-05
475 REGULATION OF FAT CELL DIFFERENTIATION 37 106 2.641e-06 2.576e-05
476 CARDIAC VENTRICLE DEVELOPMENT 37 106 2.641e-06 2.576e-05
477 CELLULAR MACROMOLECULE LOCALIZATION 262 1234 2.639e-06 2.576e-05
478 RESPONSE TO INSULIN 60 205 2.659e-06 2.589e-05
479 RENAL SYSTEM PROCESS 36 102 2.671e-06 2.594e-05
480 MEMORY 35 98 2.681e-06 2.599e-05
481 NEGATIVE CHEMOTAXIS 19 39 2.774e-06 2.683e-05
482 NEGATIVE REGULATION OF CELL GROWTH 52 170 2.94e-06 2.838e-05
483 REGULATION OF SMOOTH MUSCLE CONTRACTION 25 60 2.974e-06 2.865e-05
484 REGULATION OF SYNAPTIC PLASTICITY 45 140 3.108e-06 2.988e-05
485 DENDRITE DEVELOPMENT 30 79 3.229e-06 3.098e-05
486 REGULATION OF POTASSIUM ION TRANSPORT 31 83 3.353e-06 3.21e-05
487 LIPID PHOSPHORYLATION 35 99 3.499e-06 3.343e-05
488 RESPONSE TO OXIDATIVE STRESS 91 352 3.532e-06 3.367e-05
489 REGULATION OF HORMONE SECRETION 72 262 3.654e-06 3.476e-05
490 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 27 68 3.678e-06 3.493e-05
491 CYCLIC NUCLEOTIDE METABOLIC PROCESS 24 57 3.745e-06 3.534e-05
492 ENDOTHELIAL CELL MIGRATION 24 57 3.745e-06 3.534e-05
493 BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 14 24 3.739e-06 3.534e-05
494 REGULATION OF MEMBRANE REPOLARIZATION 16 30 3.756e-06 3.538e-05
495 DIVALENT INORGANIC CATION HOMEOSTASIS 89 343 3.832e-06 3.602e-05
496 RESPONSE TO DRUG 107 431 3.903e-06 3.661e-05
497 POSITIVE REGULATION OF STEM CELL PROLIFERATION 25 61 4.258e-06 3.987e-05
498 RETINA VASCULATURE DEVELOPMENT IN CAMERA TYPE EYE 11 16 4.409e-06 4.12e-05
499 REGULATION OF NEUROTRANSMITTER LEVELS 56 190 4.462e-06 4.16e-05
500 POSITIVE REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 35 100 4.541e-06 4.226e-05
501 REGULATION OF STEM CELL PROLIFERATION 32 88 4.561e-06 4.236e-05
502 REPRODUCTION 272 1297 4.671e-06 4.33e-05
503 IN UTERO EMBRYONIC DEVELOPMENT 82 311 4.701e-06 4.349e-05
504 POSITIVE REGULATION OF RECEPTOR MEDIATED ENDOCYTOSIS 21 47 4.829e-06 4.458e-05
505 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 40 121 4.986e-06 4.594e-05
506 REGULATION OF PROTEIN AUTOPHOSPHORYLATION 18 37 5.202e-06 4.784e-05
507 NEGATIVE REGULATION OF SECRETION 58 200 5.302e-06 4.866e-05
508 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 93 365 5.312e-06 4.866e-05
509 REGULATION OF ORGAN GROWTH 28 73 5.423e-06 4.958e-05
510 PLATELET DERIVED GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 17 34 5.929e-06 5.388e-05
511 POSITIVE REGULATION OF SODIUM ION TRANSPORT 17 34 5.929e-06 5.388e-05
512 CAMP METABOLIC PROCESS 17 34 5.929e-06 5.388e-05
513 NEGATIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 41 126 5.955e-06 5.401e-05
514 APOPTOTIC SIGNALING PATHWAY 77 289 5.994e-06 5.426e-05
515 RESPONSE TO ORGANOPHOSPHORUS 44 139 6.221e-06 5.61e-05
516 ACTIN FILAMENT ORGANIZATION 52 174 6.22e-06 5.61e-05
517 EMBRYONIC SKELETAL SYSTEM DEVELOPMENT 40 122 6.255e-06 5.619e-05
518 REGULATION OF EPITHELIAL CELL DIFFERENTIATION 40 122 6.255e-06 5.619e-05
519 REGULATION OF CATABOLIC PROCESS 165 731 6.29e-06 5.639e-05
520 REGENERATION 49 161 6.537e-06 5.849e-05
521 ADULT BEHAVIOR 43 135 6.613e-06 5.906e-05
522 METAL ION TRANSPORT 136 582 6.632e-06 5.911e-05
523 REGULATION OF EMBRYONIC DEVELOPMENT 38 114 6.828e-06 6.075e-05
524 NEGATIVE REGULATION OF WNT SIGNALING PATHWAY 57 197 6.865e-06 6.096e-05
525 REGULATION OF HEMOPOIESIS 82 314 6.973e-06 6.18e-05
526 REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 27 70 7.019e-06 6.209e-05
527 REGULATION OF MEMBRANE DEPOLARIZATION 19 41 7.056e-06 6.23e-05
528 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL BY SARCOPLASMIC RETICULUM 14 25 7.213e-06 6.356e-05
529 DIGESTIVE TRACT MORPHOGENESIS 21 48 7.262e-06 6.388e-05
530 NEGATIVE REGULATION OF CANONICAL WNT SIGNALING PATHWAY 49 162 7.897e-06 6.907e-05
531 POSITIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 49 162 7.897e-06 6.907e-05
532 MESONEPHROS DEVELOPMENT 32 90 7.873e-06 6.907e-05
533 REGULATION OF LEUKOCYTE MIGRATION 46 149 8.154e-06 7.119e-05
534 REGULATION OF HORMONE LEVELS 115 478 8.382e-06 7.249e-05
535 POSITIVE REGULATION OF POTASSIUM ION TRANSPORT 18 38 8.372e-06 7.249e-05
536 REGULATION OF RENAL SYSTEM PROCESS 18 38 8.372e-06 7.249e-05
537 POSITIVE REGULATION OF ORGAN GROWTH 18 38 8.372e-06 7.249e-05
538 REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 18 38 8.372e-06 7.249e-05
539 REGULATION OF LIPID METABOLIC PROCESS 75 282 8.429e-06 7.277e-05
540 REGIONALIZATION 81 311 8.803e-06 7.585e-05
541 ENDOTHELIAL CELL DEVELOPMENT 20 45 8.94e-06 7.675e-05
542 SMOOTH MUSCLE CONTRACTION 20 45 8.94e-06 7.675e-05
543 REGULATION OF SEQUESTERING OF CALCIUM ION 36 107 9.314e-06 7.952e-05
544 SYNAPTIC SIGNALING 104 424 9.288e-06 7.952e-05
545 PLATELET DEGRANULATION 36 107 9.314e-06 7.952e-05
546 REGULATION OF MUSCLE TISSUE DEVELOPMENT 35 103 9.625e-06 8.202e-05
547 REGULATION OF BINDING 75 283 9.655e-06 8.213e-05
548 REGULATION OF CELL SIZE 51 172 9.697e-06 8.234e-05
549 RESPONSE TO MONOAMINE 17 35 9.769e-06 8.265e-05
550 REGULATION OF PROTEIN TARGETING 80 307 9.766e-06 8.265e-05
551 OUTFLOW TRACT MORPHOGENESIS 23 56 9.791e-06 8.268e-05
552 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 34 99 9.891e-06 8.338e-05
553 REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 28 75 9.932e-06 8.341e-05
554 NEURAL CREST CELL DIFFERENTIATION 28 75 9.932e-06 8.341e-05
555 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 33 95 1.01e-05 8.471e-05
556 REGULATION OF SYNAPSE ASSEMBLY 29 79 1.017e-05 8.512e-05
557 POSITIVE REGULATION OF CHEMOTAXIS 39 120 1.026e-05 8.574e-05
558 CELLULAR RESPONSE TO CALCIUM ION 21 49 1.075e-05 8.951e-05
559 CARDIAC CELL DEVELOPMENT 21 49 1.075e-05 8.951e-05
560 CATION TRANSPORT 176 796 1.134e-05 9.421e-05
561 MECHANOSENSORY BEHAVIOR 9 12 1.158e-05 9.605e-05
562 RESPONSE TO METAL ION 85 333 1.229e-05 0.0001018
563 REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 15 29 1.24e-05 0.0001023
564 POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 15 29 1.24e-05 0.0001023
565 CELLULAR RESPONSE TO AMINO ACID STIMULUS 22 53 1.242e-05 0.0001023
566 REGULATION OF AMINE TRANSPORT 27 72 1.293e-05 0.0001063
567 REGULATION OF NEURON DEATH 68 252 1.3e-05 0.0001067
568 MESODERMAL CELL DIFFERENTIATION 14 26 1.327e-05 0.0001087
569 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 189 867 1.345e-05 0.0001098
570 CELLULAR RESPONSE TO INORGANIC SUBSTANCE 47 156 1.343e-05 0.0001098
571 TISSUE MIGRATION 30 84 1.352e-05 0.0001102
572 RAS PROTEIN SIGNAL TRANSDUCTION 44 143 1.394e-05 0.0001134
573 REGULATION OF CELL ACTIVATION 115 484 1.528e-05 0.0001241
574 REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 21 50 1.569e-05 0.0001267
575 CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 17 36 1.569e-05 0.0001267
576 CELLULAR RESPONSE TO CAMP 21 50 1.569e-05 0.0001267
577 REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 25 65 1.61e-05 0.0001298
578 CELLULAR RESPONSE TO OXIDATIVE STRESS 53 184 1.628e-05 0.0001311
579 NEGATIVE REGULATION OF STEM CELL DIFFERENTIATION 19 43 1.655e-05 0.000133
580 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 38 118 1.677e-05 0.0001345
581 EMBRYONIC SKELETAL SYSTEM MORPHOGENESIS 32 93 1.708e-05 0.0001365
582 MULTICELLULAR ORGANISM METABOLIC PROCESS 32 93 1.708e-05 0.0001365
583 MYELOID CELL DIFFERENTIATION 54 189 1.754e-05 0.00014
584 CARDIAC SEPTUM DEVELOPMENT 30 85 1.765e-05 0.0001404
585 PALATE DEVELOPMENT 30 85 1.765e-05 0.0001404
586 REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION 57 203 1.825e-05 0.0001449
587 EMBRYONIC DIGESTIVE TRACT DEVELOPMENT 16 33 1.837e-05 0.0001454
588 EMBRYONIC EYE MORPHOGENESIS 16 33 1.837e-05 0.0001454
589 CELLULAR RESPONSE TO EXTERNAL STIMULUS 70 264 1.846e-05 0.0001459
590 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION 36 110 1.863e-05 0.0001469
591 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 94 381 1.915e-05 0.0001508
592 T CELL DIFFERENTIATION 39 123 1.956e-05 0.0001537
593 GLIAL CELL DIFFERENTIATION 42 136 1.96e-05 0.0001538
594 RESPONSE TO CYTOKINE 159 714 2.001e-05 0.0001567
595 NEGATIVE REGULATION OF SYNAPTIC TRANSMISSION 24 62 2.085e-05 0.000163
596 REGULATION OF DENDRITIC SPINE MORPHOGENESIS 15 30 2.104e-05 0.0001643
597 VASCULAR PROCESS IN CIRCULATORY SYSTEM 48 163 2.131e-05 0.0001661
598 RESPONSE TO ESTROGEN 60 218 2.16e-05 0.0001681
599 NEGATIVE REGULATION OF CELLULAR RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULUS 25 66 2.19e-05 0.0001696
600 REGULATION OF VASOCONSTRICTION 25 66 2.19e-05 0.0001696
601 NEGATIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 25 66 2.19e-05 0.0001696
602 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 37 115 2.202e-05 0.0001702
603 ESTABLISHMENT OF PROTEIN LOCALIZATION TO PLASMA MEMBRANE 31 90 2.244e-05 0.0001732
604 ARTERY MORPHOGENESIS 21 51 2.257e-05 0.0001735
605 NEGATIVE REGULATION OF CHEMOTAXIS 21 51 2.257e-05 0.0001735
606 REGULATION OF PEPTIDE SECRETION 58 209 2.259e-05 0.0001735
607 REGULATION OF PEPTIDE TRANSPORT 68 256 2.267e-05 0.0001737
608 NEGATIVE REGULATION OF CELL ADHESION 61 223 2.269e-05 0.0001737
609 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 30 86 2.289e-05 0.0001749
610 SMOOTH MUSCLE TISSUE DEVELOPMENT 11 18 2.327e-05 0.0001775
611 HIPPO SIGNALING 14 27 2.34e-05 0.0001782
612 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 120 514 2.368e-05 0.00018
613 CIRCADIAN RHYTHM 42 137 2.383e-05 0.0001806
614 SKELETAL MUSCLE ORGAN DEVELOPMENT 42 137 2.383e-05 0.0001806
615 ENDOCYTOSIS 119 509 2.391e-05 0.0001809
616 REGULATION OF MUSCLE HYPERTROPHY 17 37 2.46e-05 0.0001858
617 EMBRYONIC CAMERA TYPE EYE MORPHOGENESIS 13 24 2.499e-05 0.0001884
618 REGULATION OF CARDIAC MUSCLE CELL MEMBRANE REPOLARIZATION 12 21 2.519e-05 0.0001896
619 REGULATION OF CALCIUM ION IMPORT 34 103 2.566e-05 0.0001926
620 REGULATION OF MUSCLE ORGAN DEVELOPMENT 34 103 2.566e-05 0.0001926
621 POSITIVE REGULATION OF GROWTH 64 238 2.585e-05 0.0001937
622 LIPID MODIFICATION 58 210 2.629e-05 0.0001967
623 POSITIVE REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORT 23 59 2.697e-05 0.0002014
624 TUBE FORMATION 40 129 2.754e-05 0.0002053
625 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 20 48 2.863e-05 0.0002132
626 REGULATION OF MYELOID CELL DIFFERENTIATION 52 183 2.926e-05 0.0002175
627 RESPONSE TO FLUID SHEAR STRESS 16 34 2.943e-05 0.000218
628 REGULATION OF MESENCHYMAL CELL PROLIFERATION 16 34 2.943e-05 0.000218
629 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 73 282 2.971e-05 0.0002198
630 NEGATIVE REGULATION OF RESPONSE TO WOUNDING 46 156 3.016e-05 0.0002228
631 MULTICELLULAR ORGANISMAL MACROMOLECULE METABOLIC PROCESS 28 79 3.041e-05 0.0002239
632 REGULATION OF RELEASE OF SEQUESTERED CALCIUM ION INTO CYTOSOL 27 75 3.047e-05 0.0002239
633 MULTI ORGANISM BEHAVIOR 27 75 3.047e-05 0.0002239
634 POSITIVE REGULATION OF KIDNEY DEVELOPMENT 18 41 3.064e-05 0.0002249
635 GLYCEROPHOSPHOLIPID METABOLIC PROCESS 76 297 3.157e-05 0.0002314
636 REGULATION OF VASCULOGENESIS 9 13 3.213e-05 0.0002339
637 VASCULAR SMOOTH MUSCLE CELL DIFFERENTIATION 9 13 3.213e-05 0.0002339
638 EYELID DEVELOPMENT IN CAMERA TYPE EYE 9 13 3.213e-05 0.0002339
639 ACTIVATION OF MAPKK ACTIVITY 21 52 3.204e-05 0.0002339
640 POSITIVE REGULATION OF PROTEIN IMPORT 34 104 3.218e-05 0.000234
641 DEVELOPMENTAL MATURATION 54 193 3.327e-05 0.0002415
642 LIPID LOCALIZATION 69 264 3.484e-05 0.0002525
643 REGULATION OF CELL SHAPE 42 139 3.491e-05 0.0002526
644 HOMEOSTASIS OF NUMBER OF CELLS 50 175 3.524e-05 0.0002546
645 CELLULAR CHEMICAL HOMEOSTASIS 130 570 3.568e-05 0.0002574
646 REGULATION OF WOUND HEALING 39 126 3.606e-05 0.0002597
647 REGULATION OF GLUCOSE IMPORT 23 60 3.699e-05 0.0002648
648 STEM CELL PROLIFERATION 23 60 3.699e-05 0.0002648
649 REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 23 60 3.699e-05 0.0002648
650 OLIGODENDROCYTE DIFFERENTIATION 23 60 3.699e-05 0.0002648
651 SUBSTRATE ADHESION DEPENDENT CELL SPREADING 17 38 3.774e-05 0.0002697
652 REGULATION OF SYSTEMIC ARTERIAL BLOOD PRESSURE 29 84 3.881e-05 0.0002769
653 PHOSPHATIDYLINOSITOL 3 PHOSPHATE BIOSYNTHETIC PROCESS 20 49 4.097e-05 0.0002919
654 CELLULAR HOMEOSTASIS 150 676 4.115e-05 0.0002928
655 REGULATION OF MONONUCLEAR CELL MIGRATION 10 16 4.245e-05 0.0002993
656 REGULATION OF MACROPHAGE CHEMOTAXIS 10 16 4.245e-05 0.0002993
657 NEURON CELL CELL ADHESION 10 16 4.245e-05 0.0002993
658 RESPONSE TO EPINEPHRINE 10 16 4.245e-05 0.0002993
659 STRIATUM DEVELOPMENT 10 16 4.245e-05 0.0002993
660 REGULATION OF EXTENT OF CELL GROWTH 33 101 4.233e-05 0.0002993
661 NEGATIVE REGULATION OF CELL ACTIVATION 46 158 4.278e-05 0.0003011
662 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 159 724 4.31e-05 0.000303
663 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 21 53 4.492e-05 0.0003153
664 DENDRITE MORPHOGENESIS 18 42 4.544e-05 0.0003185
665 CELLULAR RESPONSE TO BIOTIC STIMULUS 47 163 4.637e-05 0.0003245
666 EXOCYTOSIS 78 310 4.663e-05 0.0003258
667 REGULATION OF CARDIAC MUSCLE CONTRACTION BY REGULATION OF THE RELEASE OF SEQUESTERED CALCIUM ION 11 19 4.707e-05 0.0003259
668 POSITIVE REGULATION OF MUSCLE HYPERTROPHY 12 22 4.713e-05 0.0003259
669 REGULATION OF CARDIAC MUSCLE CELL ACTION POTENTIAL 11 19 4.707e-05 0.0003259
670 CENTRAL NERVOUS SYSTEM PROJECTION NEURON AXONOGENESIS 12 22 4.713e-05 0.0003259
671 POSITIVE REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 11 19 4.707e-05 0.0003259
672 GLOMERULAR EPITHELIUM DEVELOPMENT 11 19 4.707e-05 0.0003259
673 POSITIVE REGULATION OF CARDIAC MUSCLE HYPERTROPHY 12 22 4.713e-05 0.0003259
674 POST EMBRYONIC DEVELOPMENT 30 89 4.818e-05 0.0003326
675 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 90 370 5.008e-05 0.0003452
676 POSITIVE REGULATION OF SYNAPSE ASSEMBLY 23 61 5.023e-05 0.0003458
677 CYCLIC NUCLEOTIDE MEDIATED SIGNALING 19 46 5.22e-05 0.0003588
678 POSITIVE REGULATION OF AXONOGENESIS 25 69 5.237e-05 0.0003589
679 RESPONSE TO ACTIVITY 25 69 5.237e-05 0.0003589
680 HINDBRAIN DEVELOPMENT 41 137 5.486e-05 0.0003754
681 SALIVARY GLAND DEVELOPMENT 15 32 5.527e-05 0.0003771
682 NEGATIVE REGULATION OF LEUKOCYTE MIGRATION 15 32 5.527e-05 0.0003771
683 GLYCEROLIPID METABOLIC PROCESS 87 356 5.545e-05 0.0003777
684 RESPONSE TO ESTRADIOL 43 146 5.557e-05 0.000378
685 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 178 829 5.754e-05 0.0003909
686 REGULATION OF ORGANIC ACID TRANSPORT 20 50 5.782e-05 0.0003922
687 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 35 111 5.799e-05 0.0003928
688 REGULATION OF NEURON APOPTOTIC PROCESS 53 192 5.812e-05 0.000393
689 REGULATION OF ANION TRANSPORT 41 138 6.584e-05 0.0004446
690 REGULATION OF RECEPTOR MEDIATED ENDOCYTOSIS 27 78 6.719e-05 0.0004524
691 RENAL TUBULE DEVELOPMENT 27 78 6.719e-05 0.0004524
692 FOREBRAIN GENERATION OF NEURONS 24 66 6.867e-05 0.0004611
693 LENS DEVELOPMENT IN CAMERA TYPE EYE 24 66 6.867e-05 0.0004611
694 GLUCOSE HOMEOSTASIS 48 170 6.912e-05 0.0004628
695 CARBOHYDRATE HOMEOSTASIS 48 170 6.912e-05 0.0004628
696 EXTRINSIC APOPTOTIC SIGNALING PATHWAY 32 99 6.948e-05 0.0004645
697 STEROID HORMONE MEDIATED SIGNALING PATHWAY 38 125 6.965e-05 0.0004649
698 NEUROMUSCULAR JUNCTION DEVELOPMENT 16 36 7.022e-05 0.0004668
699 REGULATION OF ERYTHROCYTE DIFFERENTIATION 16 36 7.022e-05 0.0004668
700 LEUKOCYTE CELL CELL ADHESION 66 255 7.011e-05 0.0004668
701 RESPONSE TO AMINO ACID 35 112 7.12e-05 0.0004726
702 INTERACTION WITH HOST 40 134 7.154e-05 0.0004742
703 ENDOMEMBRANE SYSTEM ORGANIZATION 108 465 7.386e-05 0.0004889
704 ION TRANSMEMBRANE TRANSPORT 176 822 7.403e-05 0.0004893
705 LIPID METABOLIC PROCESS 238 1158 7.427e-05 0.0004901
706 GOLGI TO PLASMA MEMBRANE PROTEIN TRANSPORT 13 26 7.521e-05 0.000495
707 REGULATION OF AMINO ACID TRANSPORT 13 26 7.521e-05 0.000495
708 POSITIVE REGULATION OF METANEPHROS DEVELOPMENT 9 14 7.68e-05 0.0005019
709 VASCULAR ENDOTHELIAL GROWTH FACTOR SIGNALING PATHWAY 9 14 7.68e-05 0.0005019
710 INSULIN LIKE GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 9 14 7.68e-05 0.0005019
711 VOCALIZATION BEHAVIOR 9 14 7.68e-05 0.0005019
712 CRANIOFACIAL SUTURE MORPHOGENESIS 9 14 7.68e-05 0.0005019
713 ANTERIOR POSTERIOR PATTERN SPECIFICATION 53 194 7.83e-05 0.000511
714 REGULATION OF LEUKOCYTE DIFFERENTIATION 61 232 7.993e-05 0.0005209
715 TISSUE REMODELING 29 87 8.04e-05 0.0005232
716 LEUKOCYTE CHEMOTAXIS 36 117 8.099e-05 0.0005258
717 NEGATIVE REGULATION OF NEURON DEATH 48 171 8.102e-05 0.0005258
718 RESPONSE TO CAMP 33 104 8.118e-05 0.0005261
719 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 87 360 8.463e-05 0.0005477
720 NEURON RECOGNITION 15 33 8.602e-05 0.0005559
721 REGULATION OF SMOOTH MUSCLE CELL DIFFERENTIATION 11 20 8.908e-05 0.0005733
722 RELAXATION OF MUSCLE 11 20 8.908e-05 0.0005733
723 MELANOCYTE DIFFERENTIATION 11 20 8.908e-05 0.0005733
724 RESPONSE TO REACTIVE OXYGEN SPECIES 52 191 0.0001002 0.0006441
725 REGULATION OF COAGULATION 29 88 0.0001013 0.0006494
726 REGULATION OF CATION CHANNEL ACTIVITY 29 88 0.0001013 0.0006494
727 CELLULAR LIPID METABOLIC PROCESS 192 913 0.0001021 0.0006536
728 CORONARY VASCULATURE DEVELOPMENT 16 37 0.000105 0.0006691
729 IMPORT INTO CELL 16 37 0.000105 0.0006691
730 AXON EXTENSION 16 37 0.000105 0.0006691
731 NEGATIVE REGULATION OF ERK1 AND ERK2 CASCADE 20 52 0.0001109 0.0007058
732 FORMATION OF PRIMARY GERM LAYER 34 110 0.0001142 0.0007257
733 SMAD PROTEIN SIGNAL TRANSDUCTION 21 56 0.0001155 0.000733
734 POSITIVE REGULATION OF PROTEIN SECRETION 56 211 0.0001172 0.0007429
735 REGULATION OF PHAGOCYTOSIS 24 68 0.0001183 0.0007491
736 POSITIVE REGULATION OF DENDRITE DEVELOPMENT 23 64 0.0001189 0.0007519
737 NEGATIVE REGULATION OF FAT CELL DIFFERENTIATION 17 41 0.0001212 0.0007652
738 ACTIVATION OF PHOSPHOLIPASE C ACTIVITY 13 27 0.0001233 0.0007755
739 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 13 27 0.0001233 0.0007755
740 CENTRAL NERVOUS SYSTEM NEURON AXONOGENESIS 13 27 0.0001233 0.0007755
741 REGULATION OF CELL CYCLE 198 949 0.0001268 0.0007963
742 FOREBRAIN NEURON DEVELOPMENT 15 34 0.0001307 0.0008196
743 NEGATIVE REGULATION OF IMMUNE EFFECTOR PROCESS 32 102 0.0001313 0.0008222
744 THYMOCYTE AGGREGATION 18 45 0.0001343 0.0008375
745 EXOCRINE SYSTEM DEVELOPMENT 18 45 0.0001343 0.0008375
746 T CELL DIFFERENTIATION IN THYMUS 18 45 0.0001343 0.0008375
747 CELLULAR RESPONSE TO EPINEPHRINE STIMULUS 8 12 0.0001371 0.0008519
748 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 8 12 0.0001371 0.0008519
749 REGULATION OF WNT SIGNALING PATHWAY PLANAR CELL POLARITY PATHWAY 8 12 0.0001371 0.0008519
750 POSITIVE REGULATION OF PROTEIN KINASE B SIGNALING 27 81 0.0001396 0.0008651
751 REGULATION OF JUN KINASE ACTIVITY 27 81 0.0001396 0.0008651
752 POSITIVE REGULATION OF RECEPTOR INTERNALIZATION 12 24 0.0001427 0.0008807
753 EPITHELIAL CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 12 24 0.0001427 0.0008807
754 NEGATIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 12 24 0.0001427 0.0008807
755 ACTIN FILAMENT BUNDLE ORGANIZATION 19 49 0.0001441 0.0008881
756 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 38 129 0.0001455 0.0008957
757 RESPONSE TO BMP 30 94 0.0001493 0.0009165
758 CELLULAR RESPONSE TO BMP STIMULUS 30 94 0.0001493 0.0009165
759 CELLULAR RESPONSE TO KETONE 25 73 0.0001499 0.0009188
760 REGULATION OF NITRIC OXIDE BIOSYNTHETIC PROCESS 20 53 0.0001509 0.0009212
761 CYTOSOLIC CALCIUM ION TRANSPORT 20 53 0.0001509 0.0009212
762 MESONEPHRIC TUBULE MORPHOGENESIS 20 53 0.0001509 0.0009212
763 POSITIVE REGULATION OF WNT SIGNALING PATHWAY 43 152 0.0001532 0.0009342
764 POSITIVE REGULATION OF BIOMINERAL TISSUE DEVELOPMENT 16 38 0.0001539 0.0009372
765 CELLULAR RESPONSE TO RETINOIC ACID 23 65 0.0001558 0.0009475
766 REGULATION OF POTASSIUM ION TRANSMEMBRANE TRANSPORT 22 61 0.0001563 0.0009496
767 NEGATIVE REGULATION OF INTRACELLULAR TRANSPORT 41 143 0.0001569 0.0009516
768 LIPID TRANSLOCATION 11 21 0.0001594 0.0009643
769 POSITIVE REGULATION OF EXCITATORY POSTSYNAPTIC POTENTIAL 11 21 0.0001594 0.0009643
770 REGULATION OF CIRCADIAN RHYTHM 32 103 0.0001609 0.0009707
771 POSITIVE REGULATION OF CALCIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 14 31 0.0001611 0.0009707
772 REGULATION OF SYNAPTIC VESICLE TRANSPORT 14 31 0.0001611 0.0009707
773 REGULATION OF EPITHELIAL CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 9 15 0.000164 0.0009871
774 RESPONSE TO PLATELET DERIVED GROWTH FACTOR 10 18 0.0001687 0.001014
775 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 60 233 0.0001694 0.001017
776 POSITIVE REGULATION OF GLUCOSE TRANSPORT 17 42 0.0001727 0.001034
777 NEGATIVE REGULATION OF IMMUNE RESPONSE 36 121 0.0001726 0.001034
778 POSITIVE REGULATION OF RESPONSE TO WOUNDING 45 162 0.000173 0.001035
779 KIDNEY MORPHOGENESIS 27 82 0.000176 0.001051
780 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 43 153 0.0001797 0.001072
781 NEGATIVE REGULATION OF PROTEIN SECRETION 33 108 0.0001821 0.001085
782 PEPTIDYL THREONINE MODIFICATION 18 46 0.000187 0.001111
783 POSITIVE REGULATION OF PHAGOCYTOSIS 18 46 0.000187 0.001111
784 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 39 135 0.0001885 0.001119
785 HORMONE MEDIATED SIGNALING PATHWAY 44 158 0.0001908 0.001131
786 REGULATION OF ACUTE INFLAMMATORY RESPONSE 25 74 0.0001915 0.001133
787 POSITIVE REGULATION OF HEART CONTRACTION 15 35 0.0001942 0.001147
788 RESPONSE TO MINERALOCORTICOID 15 35 0.0001942 0.001147
789 GLUTAMATE SECRETION 13 28 0.0001958 0.001152
790 REGULATION OF MACROPHAGE DERIVED FOAM CELL DIFFERENTIATION 13 28 0.0001958 0.001152
791 REGULATION OF FATTY ACID OXIDATION 13 28 0.0001958 0.001152
792 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 19 50 0.000197 0.001156
793 RHO PROTEIN SIGNAL TRANSDUCTION 19 50 0.000197 0.001156
794 NEURAL PRECURSOR CELL PROLIFERATION 24 70 0.0001977 0.001158
795 TRANSMISSION OF NERVE IMPULSE 20 54 0.000203 0.001187
796 VENTRICULAR SEPTUM DEVELOPMENT 20 54 0.000203 0.001187
797 CARDIAC VENTRICLE MORPHOGENESIS 22 62 0.0002052 0.001198
798 ORGANIC HYDROXY COMPOUND METABOLIC PROCESS 109 482 0.000208 0.001213
799 REGULATION OF FATTY ACID METABOLIC PROCESS 28 87 0.0002086 0.001215
800 PHOSPHOLIPID METABOLIC PROCESS 86 364 0.0002099 0.001221
801 LIMBIC SYSTEM DEVELOPMENT 31 100 0.0002112 0.001227
802 POSITIVE REGULATION OF CATABOLIC PROCESS 92 395 0.0002192 0.001272
803 REGULATION OF AXON GUIDANCE 16 39 0.0002215 0.001282
804 LONG TERM SYNAPTIC POTENTIATION 16 39 0.0002215 0.001282
805 CALCIUM ION TRANSMEMBRANE TRANSPORT 44 159 0.0002226 0.001286
806 POSITIVE REGULATION OF BINDING 37 127 0.0002257 0.001302
807 REGULATION OF CELL CELL ADHESION 89 380 0.0002256 0.001302
808 POSITIVE REGULATION OF HOMEOSTATIC PROCESS 56 216 0.0002272 0.001308
809 REGULATION OF LEUKOCYTE APOPTOTIC PROCESS 26 79 0.0002321 0.001335
810 CELLULAR EXTRAVASATION 12 25 0.0002336 0.00134
811 POSTSYNAPTIC MEMBRANE ORGANIZATION 12 25 0.0002336 0.00134
812 CEREBRAL CORTEX CELL MIGRATION 17 43 0.0002423 0.001389
813 REGULATION OF ORGAN FORMATION 14 32 0.0002433 0.001391
814 ADIPOSE TISSUE DEVELOPMENT 14 32 0.0002433 0.001391
815 NEGATIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 24 71 0.0002527 0.001441
816 ADHERENS JUNCTION ORGANIZATION 24 71 0.0002527 0.001441
817 CELLULAR RESPONSE TO DRUG 23 67 0.0002609 0.001486
818 HOMOTYPIC CELL CELL ADHESION 19 51 0.0002661 0.001514
819 NEGATIVE REGULATION OF MUSCLE CONTRACTION 11 22 0.0002716 0.001534
820 BONE CELL DEVELOPMENT 11 22 0.0002716 0.001534
821 POSITIVE REGULATION OF HEART RATE 11 22 0.0002716 0.001534
822 POSITIVE REGULATION OF PROTEIN AUTOPHOSPHORYLATION 11 22 0.0002716 0.001534
823 CRANIAL SKELETAL SYSTEM DEVELOPMENT 20 55 0.0002703 0.001534
824 SUBPALLIUM DEVELOPMENT 11 22 0.0002716 0.001534
825 NEGATIVE REGULATION OF BLOOD CIRCULATION 15 36 0.0002828 0.001591
826 OLFACTORY LOBE DEVELOPMENT 15 36 0.0002828 0.001591
827 SEMAPHORIN PLEXIN SIGNALING PATHWAY 15 36 0.0002828 0.001591
828 REGULATION OF GLUCOSE METABOLIC PROCESS 32 106 0.0002887 0.001622
829 CELLULAR RESPONSE TO MECHANICAL STIMULUS 26 80 0.0002909 0.001633
830 REGULATION OF DNA BINDING 29 93 0.0002979 0.00167
831 NEGATIVE REGULATION OF RECEPTOR ACTIVITY 13 29 0.0003018 0.00169
832 REGULATION OF NON CANONICAL WNT SIGNALING PATHWAY 10 19 0.0003039 0.001692
833 FIBRIL ORGANIZATION 10 19 0.0003039 0.001692
834 RELAXATION OF CARDIAC MUSCLE 8 13 0.0003051 0.001692
835 KIDNEY VASCULATURE DEVELOPMENT 10 19 0.0003039 0.001692
836 RENAL SYSTEM VASCULATURE DEVELOPMENT 10 19 0.0003039 0.001692
837 MESENCHYMAL CELL PROLIFERATION 8 13 0.0003051 0.001692
838 NEGATIVE REGULATION OF LEUKOCYTE CHEMOTAXIS 8 13 0.0003051 0.001692
839 EXTRACELLULAR FIBRIL ORGANIZATION 8 13 0.0003051 0.001692
840 REGULATION OF CALCIUM MEDIATED SIGNALING 25 76 0.0003063 0.001697
841 MAMMARY GLAND MORPHOGENESIS 16 40 0.0003133 0.001729
842 FORELIMB MORPHOGENESIS 16 40 0.0003133 0.001729
843 POSITIVE REGULATION OF CELL MATRIX ADHESION 16 40 0.0003133 0.001729
844 REGULATION OF SMAD PROTEIN IMPORT INTO NUCLEUS 9 16 0.0003203 0.001761
845 BRANCHING INVOLVED IN SALIVARY GLAND MORPHOGENESIS 9 16 0.0003203 0.001761
846 REGULATION OF FATTY ACID BETA OXIDATION 9 16 0.0003203 0.001761
847 NERVE DEVELOPMENT 23 68 0.0003337 0.001833
848 BRANCHING INVOLVED IN URETERIC BUD MORPHOGENESIS 17 44 0.0003351 0.001839
849 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 38 134 0.0003407 0.001867
850 REGULATION OF NEUROTRANSMITTER TRANSPORT 22 64 0.0003444 0.001886
851 POSITIVE REGULATION OF CALCIUM ION TRANSPORT INTO CYTOSOL 19 52 0.0003555 0.001944
852 REGULATION OF DENDRITIC SPINE DEVELOPMENT 20 56 0.0003563 0.001946
853 POSITIVE REGULATION OF FATTY ACID METABOLIC PROCESS 14 33 0.0003592 0.00196
854 NEGATIVE REGULATION OF CARTILAGE DEVELOPMENT 12 26 0.0003694 0.00201
855 RESPONSE TO CORTICOSTERONE 12 26 0.0003694 0.00201
856 REGULATION OF CYTOKINE PRODUCTION 123 563 0.0003777 0.002053
857 REGULATION OF PROTEIN KINASE B SIGNALING 35 121 0.0003816 0.002072
858 ACTOMYOSIN STRUCTURE ORGANIZATION 25 77 0.0003838 0.002079
859 REGULATION OF BMP SIGNALING PATHWAY 25 77 0.0003838 0.002079
860 NEGATIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 38 135 0.0004003 0.002166
861 NEGATIVE REGULATION OF MAP KINASE ACTIVITY 24 73 0.0004045 0.002183
862 POSITIVE REGULATION OF CATION CHANNEL ACTIVITY 15 37 0.0004041 0.002183
863 STRIATED MUSCLE CONTRACTION 30 99 0.0004097 0.002209
864 NEGATIVE REGULATION OF CYTOPLASMIC TRANSPORT 34 117 0.000418 0.002248
865 MAMMARY GLAND DEVELOPMENT 34 117 0.000418 0.002248
866 AORTA DEVELOPMENT 16 41 0.0004363 0.002344
867 CALCIUM ION IMPORT 22 65 0.000441 0.002358
868 CELL MATURATION 37 131 0.0004408 0.002358
869 REGULATION OF RESPONSE TO OXIDATIVE STRESS 22 65 0.000441 0.002358
870 NEGATIVE REGULATION OF AXONOGENESIS 22 65 0.000441 0.002358
871 NEGATIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 11 23 0.0004437 0.002362
872 REGULATION OF OSTEOBLAST PROLIFERATION 11 23 0.0004437 0.002362
873 STRIATED MUSCLE ADAPTATION 11 23 0.0004437 0.002362
874 INNERVATION 11 23 0.0004437 0.002362
875 RECEPTOR METABOLIC PROCESS 26 82 0.0004489 0.002387
876 NEURON MATURATION 13 30 0.0004531 0.002396
877 NEGATIVE REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 13 30 0.0004531 0.002396
878 NEGATIVE REGULATION OF CELL MATRIX ADHESION 13 30 0.0004531 0.002396
879 MODULATION OF EXCITATORY POSTSYNAPTIC POTENTIAL 13 30 0.0004531 0.002396
880 ESTABLISHMENT OF ENDOTHELIAL BARRIER 13 30 0.0004531 0.002396
881 CELLULAR RESPONSE TO REACTIVE OXYGEN SPECIES 31 104 0.000455 0.002403
882 POSITIVE REGULATION OF RECEPTOR ACTIVITY 17 45 0.000457 0.002411
883 CIRCADIAN REGULATION OF GENE EXPRESSION 20 57 0.0004652 0.002448
884 AMMONIUM TRANSPORT 20 57 0.0004652 0.002448
885 CARDIAC SEPTUM MORPHOGENESIS 18 49 0.0004676 0.002459
886 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 19 53 0.0004698 0.002462
887 NEURON PROJECTION EXTENSION 19 53 0.0004698 0.002462
888 NEGATIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 38 136 0.000469 0.002462
889 METENCEPHALON DEVELOPMENT 30 100 0.0004947 0.002589
890 MESODERM DEVELOPMENT 34 118 0.000496 0.002593
891 REGULATION OF HOMOTYPIC CELL CELL ADHESION 73 307 0.000498 0.002601
892 RESPONSE TO HYDROGEN PEROXIDE 32 109 0.0004999 0.002608
893 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 24 74 0.0005067 0.002634
894 NEGATIVE REGULATION OF HORMONE SECRETION 24 74 0.0005067 0.002634
895 CELL CELL JUNCTION ASSEMBLY 24 74 0.0005067 0.002634
896 POSITIVE REGULATION OF EPITHELIAL TO MESENCHYMAL TRANSITION 14 34 0.0005192 0.002687
897 NEGATIVE REGULATION OF CELL JUNCTION ASSEMBLY 10 20 0.0005186 0.002687
898 OLIGODENDROCYTE DEVELOPMENT 14 34 0.0005192 0.002687
899 MICROVILLUS ORGANIZATION 10 20 0.0005186 0.002687
900 MYELOID LEUKOCYTE DIFFERENTIATION 29 96 0.000537 0.002773
901 REGULATION OF LEUKOCYTE CHEMOTAXIS 29 96 0.000537 0.002773
902 ACTIVATION OF MAPK ACTIVITY 38 137 0.000548 0.002827
903 ORGAN REGENERATION 26 83 0.0005531 0.002847
904 RESPONSE TO FATTY ACID 26 83 0.0005531 0.002847
905 CARDIAC MUSCLE ADAPTATION 7 11 0.0005647 0.002892
906 EXCITATORY POSTSYNAPTIC POTENTIAL 12 27 0.0005662 0.002892
907 REGULATION OF VENTRICULAR CARDIAC MUSCLE CELL ACTION POTENTIAL 7 11 0.0005647 0.002892
908 MUSCLE HYPERTROPHY IN RESPONSE TO STRESS 7 11 0.0005647 0.002892
909 REGULATION OF CATENIN IMPORT INTO NUCLEUS 12 27 0.0005662 0.002892
910 POSITIVE REGULATION OF POTASSIUM ION TRANSMEMBRANE TRANSPORT 12 27 0.0005662 0.002892
911 CARDIAC MUSCLE HYPERTROPHY IN RESPONSE TO STRESS 7 11 0.0005647 0.002892
912 REGULATION OF PHOSPHATASE ACTIVITY 36 128 0.0005701 0.002907
913 REGULATION OF LEUKOCYTE MEDIATED IMMUNITY 42 156 0.0005703 0.002907
914 CYCLIC NUCLEOTIDE CATABOLIC PROCESS 9 17 0.0005817 0.002951
915 EMBRYONIC DIGESTIVE TRACT MORPHOGENESIS 9 17 0.0005817 0.002951
916 NEGATIVE REGULATION OF LIPID STORAGE 9 17 0.0005817 0.002951
917 DEFINITIVE HEMOPOIESIS 9 17 0.0005817 0.002951
918 AUTONOMIC NERVOUS SYSTEM DEVELOPMENT 16 42 0.0005985 0.003034
919 POSITIVE REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 8 14 0.0006095 0.003063
920 EPITHELIAL CELL CELL ADHESION 8 14 0.0006095 0.003063
921 REGULATION OF GLOMERULUS DEVELOPMENT 8 14 0.0006095 0.003063
922 METANEPHRIC MESENCHYME DEVELOPMENT 8 14 0.0006095 0.003063
923 POSITIVE REGULATION OF CELL SIZE 8 14 0.0006095 0.003063
924 POSITIVE REGULATION OF FATTY ACID OXIDATION 8 14 0.0006095 0.003063
925 CAMP CATABOLIC PROCESS 8 14 0.0006095 0.003063
926 REGULATION OF CAMP DEPENDENT PROTEIN KINASE ACTIVITY 8 14 0.0006095 0.003063
927 PROTEIN DEPHOSPHORYLATION 49 190 0.0006139 0.003081
928 POSITIVE REGULATION OF CALCIUM ION IMPORT 19 54 0.0006147 0.003082
929 VISUAL BEHAVIOR 18 50 0.0006199 0.003105
930 ODONTOGENESIS OF DENTIN CONTAINING TOOTH 24 75 0.0006309 0.003153
931 NEGATIVE REGULATION OF CELL CYCLE 97 433 0.0006304 0.003153
932 POSITIVE REGULATION OF MUSCLE CELL DIFFERENTIATION 26 84 0.0006778 0.003384
933 MULTI ORGANISM REPRODUCTIVE PROCESS 182 891 0.0006958 0.00347
934 CARDIAC EPITHELIAL TO MESENCHYMAL TRANSITION 11 24 0.0006984 0.003479
935 INSULIN RECEPTOR SIGNALING PATHWAY 25 80 0.0007286 0.003626
936 EMBRYONIC CAMERA TYPE EYE DEVELOPMENT 14 35 0.0007359 0.003654
937 REGULATION OF RESPONSE TO REACTIVE OXYGEN SPECIES 14 35 0.0007359 0.003654
938 EPITHELIAL CELL PROLIFERATION 27 89 0.0007635 0.003788
939 REGULATION OF EPITHELIAL CELL APOPTOTIC PROCESS 20 59 0.0007718 0.003825
940 AMINOGLYCAN BIOSYNTHETIC PROCESS 31 107 0.0007759 0.003841
941 MYELOID LEUKOCYTE ACTIVATION 29 98 0.000778 0.003847
942 POSITIVE REGULATION OF HEMOPOIESIS 43 163 0.0007804 0.003852
943 GLIAL CELL DEVELOPMENT 24 76 0.0007806 0.003852
944 TRABECULA MORPHOGENESIS 15 39 0.0007833 0.003853
945 REGULATION OF MAST CELL ACTIVATION 15 39 0.0007833 0.003853
946 PEPTIDYL TYROSINE AUTOPHOSPHORYLATION 15 39 0.0007833 0.003853
947 RESPONSE TO EXTRACELLULAR STIMULUS 98 441 0.0007869 0.003866
948 NEGATIVE REGULATION OF MUSCLE CELL DIFFERENTIATION 19 55 0.0007965 0.003909
949 NEURAL TUBE DEVELOPMENT 40 149 0.0008086 0.003965
950 REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 16 43 0.0008096 0.003965
951 POSITIVE REGULATION OF DEPHOSPHORYLATION 17 47 0.0008183 0.004004
952 REGULATION OF STRIATED MUSCLE CELL DIFFERENTIATION 26 85 0.0008264 0.004039
953 NEURONAL ACTION POTENTIAL 12 28 0.0008441 0.004113
954 PURINERGIC RECEPTOR SIGNALING PATHWAY 12 28 0.0008441 0.004113
955 POSITIVE REGULATION OF PHOSPHATASE ACTIVITY 12 28 0.0008441 0.004113
956 REGULATION OF MEMBRANE PROTEIN ECTODOMAIN PROTEOLYSIS 10 21 0.0008453 0.004114
957 NEURAL TUBE FORMATION 28 94 0.000848 0.004123
958 OSTEOBLAST DIFFERENTIATION 35 126 0.0008621 0.004187
959 IMMUNE RESPONSE 219 1100 0.0008844 0.004291
960 PHENOL CONTAINING COMPOUND METABOLIC PROCESS 25 81 0.0008921 0.004324
961 REGULATION OF PROTEIN COMPLEX ASSEMBLY 85 375 0.0009091 0.004397
962 RETINA DEVELOPMENT IN CAMERA TYPE EYE 36 131 0.0009089 0.004397
963 NEGATIVE REGULATION OF CATABOLIC PROCESS 51 203 0.0009159 0.004426
964 REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 31 108 0.0009201 0.004441
965 SINGLE ORGANISM CATABOLIC PROCESS 193 957 0.0009335 0.004501
966 EMBRYONIC FORELIMB MORPHOGENESIS 13 32 0.000952 0.004576
967 METANEPHRIC NEPHRON DEVELOPMENT 13 32 0.000952 0.004576
968 CELLULAR RESPONSE TO ABIOTIC STIMULUS 63 263 0.0009517 0.004576
969 NEUROTRANSMITTER TRANSPORT 41 155 0.0009628 0.004623
970 LEUKOCYTE HOMEOSTASIS 20 60 0.0009816 0.004709
971 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 9 18 0.0009946 0.004756
972 KIDNEY MESENCHYME DEVELOPMENT 9 18 0.0009946 0.004756
973 INOSITOL PHOSPHATE MEDIATED SIGNALING 9 18 0.0009946 0.004756
974 NEGATIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 14 36 0.001024 0.004868
975 INOSITOL PHOSPHATE METABOLIC PROCESS 19 56 0.001022 0.004868
976 POSITIVE REGULATION OF AXON EXTENSION 14 36 0.001024 0.004868
977 REGULATION OF TRANSCRIPTION REGULATORY REGION DNA BINDING 14 36 0.001024 0.004868
978 CORTICAL CYTOSKELETON ORGANIZATION 14 36 0.001024 0.004868
979 HEAD MORPHOGENESIS 14 36 0.001024 0.004868
980 REGULATION OF NEURAL PRECURSOR CELL PROLIFERATION 23 73 0.00103 0.004892
981 TRANSMEMBRANE TRANSPORT 218 1098 0.001051 0.004987
982 CELL PROJECTION ASSEMBLY 63 264 0.001054 0.004992
983 REGULATION OF LIPID CATABOLIC PROCESS 18 52 0.001055 0.004994
984 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 15 40 0.001065 0.005017
985 NEGATIVE REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 15 40 0.001065 0.005017
986 DOPAMINE METABOLIC PROCESS 11 25 0.001064 0.005017
987 NEGATIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 15 40 0.001065 0.005017
988 POSITIVE REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 11 25 0.001064 0.005017
989 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 80 351 0.001068 0.005026
990 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 17 48 0.001076 0.005046
991 REGULATION OF LIPID KINASE ACTIVITY 17 48 0.001076 0.005046
992 POSITIVE REGULATION OF PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 17 48 0.001076 0.005046
993 POSITIVE REGULATION OF MUSCLE CONTRACTION 16 44 0.001081 0.005064
994 INTEGRIN MEDIATED SIGNALING PATHWAY 25 82 0.001087 0.005086
995 PEPTIDYL TYROSINE DEPHOSPHORYLATION 29 100 0.001109 0.005184
996 NEUROTRANSMITTER UPTAKE 8 15 0.001119 0.0052
997 REGULATION OF HEAT GENERATION 8 15 0.001119 0.0052
998 NEGATIVE REGULATION OF DENDRITE MORPHOGENESIS 8 15 0.001119 0.0052
999 POSITIVE REGULATION OF MACROPHAGE DERIVED FOAM CELL DIFFERENTIATION 8 15 0.001119 0.0052
1000 NEGATIVE REGULATION OF SMOOTH MUSCLE CONTRACTION 8 15 0.001119 0.0052
1001 VENTRICULAR CARDIAC MUSCLE CELL ACTION POTENTIAL 8 15 0.001119 0.0052
1002 REGULATION OF ORGANELLE ORGANIZATION 232 1178 0.001149 0.005335
1003 NEURON PROJECTION EXTENSION INVOLVED IN NEURON PROJECTION GUIDANCE 7 12 0.001163 0.005354
1004 ROUNDABOUT SIGNALING PATHWAY 7 12 0.001163 0.005354
1005 REGULATION OF BROWN FAT CELL DIFFERENTIATION 7 12 0.001163 0.005354
1006 AXON EXTENSION INVOLVED IN AXON GUIDANCE 7 12 0.001163 0.005354
1007 CENTRAL NERVOUS SYSTEM MYELINATION 7 12 0.001163 0.005354
1008 AXON ENSHEATHMENT IN CENTRAL NERVOUS SYSTEM 7 12 0.001163 0.005354
1009 VASCULAR SMOOTH MUSCLE CONTRACTION 7 12 0.001163 0.005354
1010 REGULATION OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR SIGNALING PATHWAY 7 12 0.001163 0.005354
1011 EMBRYONIC CAMERA TYPE EYE FORMATION 7 12 0.001163 0.005354
1012 POSITIVE REGULATION OF LIPID METABOLIC PROCESS 35 128 0.001169 0.005377
1013 REGULATION OF CHEMOKINE PRODUCTION 21 65 0.001171 0.005378
1014 CYTOSOLIC TRANSPORT 53 215 0.001172 0.005378
1015 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 39 147 0.001188 0.005446
1016 MOVEMENT IN ENVIRONMENT OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 26 87 0.00121 0.005504
1017 ENTRY INTO CELL OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 26 87 0.00121 0.005504
1018 VIRAL ENTRY INTO HOST CELL 26 87 0.00121 0.005504
1019 ENTRY INTO OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 26 87 0.00121 0.005504
1020 REGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS 26 87 0.00121 0.005504
1021 MOVEMENT IN HOST ENVIRONMENT 26 87 0.00121 0.005504
1022 ENTRY INTO HOST 26 87 0.00121 0.005504
1023 ENTRY INTO HOST CELL 26 87 0.00121 0.005504
1024 STEM CELL DIVISION 12 29 0.001227 0.005564
1025 MUSCLE ADAPTATION 12 29 0.001227 0.005564
1026 EMBRYONIC HINDLIMB MORPHOGENESIS 12 29 0.001227 0.005564
1027 PEPTIDYL AMINO ACID MODIFICATION 171 841 0.00123 0.005573
1028 MYOTUBE DIFFERENTIATION 19 57 0.001301 0.005889
1029 POST GOLGI VESICLE MEDIATED TRANSPORT 25 83 0.001316 0.005953
1030 PURINERGIC NUCLEOTIDE RECEPTOR SIGNALING PATHWAY 10 22 0.001323 0.005966
1031 SOMATIC STEM CELL DIVISION 10 22 0.001323 0.005966
1032 ACTIVATION OF PROTEIN KINASE B ACTIVITY 10 22 0.001323 0.005966
1033 NEGATIVE REGULATION OF ANION TRANSPORT 13 33 0.001337 0.006018
1034 NEGATIVE REGULATION OF JNK CASCADE 13 33 0.001337 0.006018
1035 MAMMARY GLAND EPITHELIUM DEVELOPMENT 18 53 0.001356 0.00609
1036 NEGATIVE REGULATION OF EPITHELIAL CELL MIGRATION 18 53 0.001356 0.00609
1037 MUSCLE ORGAN MORPHOGENESIS 22 70 0.001361 0.006105
1038 PEPTIDYL SERINE MODIFICATION 39 148 0.001362 0.006107
1039 HINDLIMB MORPHOGENESIS 14 37 0.001402 0.006229
1040 MATING 14 37 0.001402 0.006229
1041 ACTIN POLYMERIZATION OR DEPOLYMERIZATION 14 37 0.001402 0.006229
1042 REGULATION OF MEMBRANE LIPID DISTRIBUTION 14 37 0.001402 0.006229
1043 REGULATION OF RECEPTOR INTERNALIZATION 14 37 0.001402 0.006229
1044 POSITIVE REGULATION OF CHEMOKINE PRODUCTION 17 49 0.001399 0.006229
1045 TRANSCRIPTION INITIATION FROM RNA POLYMERASE II PROMOTER 40 153 0.001401 0.006229
1046 GLIAL CELL MIGRATION 14 37 0.001402 0.006229
1047 CAMP MEDIATED SIGNALING 14 37 0.001402 0.006229
1048 MULTICELLULAR ORGANISMAL HOMEOSTASIS 64 272 0.001409 0.006257
1049 SPINAL CORD DEVELOPMENT 30 106 0.001411 0.006259
1050 REGULATION OF LIPID STORAGE 15 41 0.001428 0.006293
1051 LUNG MORPHOGENESIS 16 45 0.001425 0.006293
1052 GOLGI TO PLASMA MEMBRANE TRANSPORT 15 41 0.001428 0.006293
1053 CELL SUBSTRATE JUNCTION ASSEMBLY 15 41 0.001428 0.006293
1054 HETEROPHILIC CELL CELL ADHESION VIA PLASMA MEMBRANE CELL ADHESION MOLECULES 16 45 0.001425 0.006293
1055 ENDOCHONDRAL BONE MORPHOGENESIS 16 45 0.001425 0.006293
1056 PROSTATE GLAND DEVELOPMENT 15 41 0.001428 0.006293
1057 PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROCESS 33 120 0.001434 0.006305
1058 CYTOKINE PRODUCTION 33 120 0.001434 0.006305
1059 REGULATION OF DEPHOSPHORYLATION 41 158 0.001437 0.006314
1060 NEUROMUSCULAR PROCESS 28 97 0.001445 0.006344
1061 ACID SECRETION 21 66 0.001456 0.006373
1062 MESODERM MORPHOGENESIS 21 66 0.001456 0.006373
1063 POSITIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 26 88 0.001454 0.006373
1064 INORGANIC ION TRANSMEMBRANE TRANSPORT 123 583 0.001499 0.006557
1065 SIGNAL RELEASE 44 173 0.001523 0.006656
1066 NEGATIVE REGULATION OF HYDROLASE ACTIVITY 88 397 0.001528 0.006668
1067 SENSORY PERCEPTION OF PAIN 23 75 0.001547 0.006748
1068 VASODILATION 11 26 0.001573 0.006832
1069 REGULATION OF REGULATED SECRETORY PATHWAY 35 130 0.001568 0.006832
1070 ENTRAINMENT OF CIRCADIAN CLOCK 11 26 0.001573 0.006832
1071 NEGATIVE REGULATION OF EMBRYONIC DEVELOPMENT 11 26 0.001573 0.006832
1072 CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS 47 188 0.001582 0.006867
1073 POSITIVE REGULATION OF BLOOD CIRCULATION 27 93 0.001586 0.006876
1074 CYTOKINESIS 25 84 0.001587 0.006876
1075 PROTEIN HOMOOLIGOMERIZATION 59 248 0.001607 0.006956
1076 ENTRAINMENT OF CIRCADIAN CLOCK BY PHOTOPERIOD 9 19 0.001616 0.006976
1077 REGULATION OF LONG TERM SYNAPTIC POTENTIATION 9 19 0.001616 0.006976
1078 POSITIVE REGULATION OF CHONDROCYTE DIFFERENTIATION 9 19 0.001616 0.006976
1079 RESPONSE TO RETINOIC ACID 30 107 0.001659 0.007152
1080 SKIN EPIDERMIS DEVELOPMENT 22 71 0.001671 0.007199
1081 REGULATION OF DEFENSE RESPONSE 155 759 0.001693 0.007279
1082 REGULATION OF IMMUNE RESPONSE 173 858 0.001692 0.007279
1083 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 28 98 0.001712 0.007355
1084 ADULT LOCOMOTORY BEHAVIOR 24 80 0.001729 0.007423
1085 CEREBELLAR CORTEX MORPHOGENESIS 12 30 0.001743 0.007453
1086 NEGATIVE REGULATION OF INTRACELLULAR STEROID HORMONE RECEPTOR SIGNALING PATHWAY 12 30 0.001743 0.007453
1087 OSTEOCLAST DIFFERENTIATION 12 30 0.001743 0.007453
1088 REGULATION OF VASCULAR PERMEABILITY 12 30 0.001743 0.007453
1089 SINGLE ORGANISM CELLULAR LOCALIZATION 180 898 0.001809 0.007731
1090 STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 29 103 0.001831 0.007816
1091 ADHERENS JUNCTION ASSEMBLY 13 34 0.001844 0.007863
1092 INTRASPECIES INTERACTION BETWEEN ORGANISMS 16 46 0.001857 0.007897
1093 SOCIAL BEHAVIOR 16 46 0.001857 0.007897
1094 EMBRYONIC CRANIAL SKELETON MORPHOGENESIS 16 46 0.001857 0.007897
1095 CALCIUM ION TRANSMEMBRANE IMPORT INTO CYTOSOL 15 42 0.001889 0.007998
1096 CATECHOLAMINE METABOLIC PROCESS 15 42 0.001889 0.007998
1097 EPITHELIAL CELL MORPHOGENESIS 15 42 0.001889 0.007998
1098 CATECHOL CONTAINING COMPOUND METABOLIC PROCESS 15 42 0.001889 0.007998
1099 CALCIUM ION IMPORT INTO CYTOSOL 15 42 0.001889 0.007998
1100 MEMBRANE ORGANIZATION 180 899 0.001903 0.008051
1101 REGULATION OF RESPIRATORY SYSTEM PROCESS 8 16 0.001917 0.008073
1102 NEGATIVE REGULATION OF ADHERENS JUNCTION ORGANIZATION 8 16 0.001917 0.008073
1103 NEGATIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 8 16 0.001917 0.008073
1104 POSITIVE REGULATION OF PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 8 16 0.001917 0.008073
1105 MEGAKARYOCYTE DEVELOPMENT 8 16 0.001917 0.008073
1106 POSITIVE REGULATION OF JUN KINASE ACTIVITY 20 63 0.001927 0.008107
1107 MUCOPOLYSACCHARIDE METABOLIC PROCESS 30 108 0.001943 0.008165
1108 PROSTATE GLAND MORPHOGENESIS 10 23 0.002 0.008361
1109 RESPONSE TO AUDITORY STIMULUS 10 23 0.002 0.008361
1110 MATING BEHAVIOR 10 23 0.002 0.008361
1111 REGULATION OF RESPIRATORY GASEOUS EXCHANGE 10 23 0.002 0.008361
1112 RENAL SYSTEM PROCESS INVOLVED IN REGULATION OF SYSTEMIC ARTERIAL BLOOD PRESSURE 10 23 0.002 0.008361
1113 MULTI ORGANISM REPRODUCTIVE BEHAVIOR 10 23 0.002 0.008361
1114 NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 49 200 0.002011 0.008401
1115 SMOOTHENED SIGNALING PATHWAY 22 72 0.002039 0.008511
1116 POSITIVE REGULATION OF INFLAMMATORY RESPONSE 31 113 0.002047 0.008533
1117 SYNAPTIC VESICLE CYCLE 26 90 0.00207 0.008625
1118 AMINOGLYCAN METABOLIC PROCESS 42 166 0.002135 0.008887
1119 REGULATION OF INTERLEUKIN 6 PRODUCTION 29 104 0.002148 0.008933
1120 REGULATION OF ANTIGEN PROCESSING AND PRESENTATION OF PEPTIDE ANTIGEN 7 13 0.002165 0.008953
1121 REGULATION OF RESPIRATORY GASEOUS EXCHANGE BY NEUROLOGICAL SYSTEM PROCESS 7 13 0.002165 0.008953
1122 PATHWAY RESTRICTED SMAD PROTEIN PHOSPHORYLATION 7 13 0.002165 0.008953
1123 LEUKOCYTE TETHERING OR ROLLING 7 13 0.002165 0.008953
1124 LEUKOCYTE ADHESION TO VASCULAR ENDOTHELIAL CELL 7 13 0.002165 0.008953
1125 REGULATION OF CELL COMMUNICATION BY ELECTRICAL COUPLING 7 13 0.002165 0.008953
1126 POSITIVE REGULATION OF CYTOKINE PRODUCTION 82 370 0.002172 0.008975
1127 EPIDERMAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 18 55 0.002179 0.008988
1128 ACTIN CYTOSKELETON REORGANIZATION 18 55 0.002179 0.008988
1129 REGULATION OF TYROSINE PHOSPHORYLATION OF STAT PROTEIN 21 68 0.002206 0.009091
1130 REGULATION OF EXOCYTOSIS 46 186 0.00222 0.00914
1131 NEGATIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 27 95 0.002228 0.009156
1132 CANONICAL WNT SIGNALING PATHWAY 27 95 0.002228 0.009156
1133 REGULATION OF NUCLEOTIDE METABOLIC PROCESS 51 211 0.002246 0.009215
1134 SKIN DEVELOPMENT 51 211 0.002246 0.009215
1135 REGULATION OF ENDOTHELIAL CELL DIFFERENTIATION 11 27 0.002264 0.009242
1136 DEVELOPMENTAL INDUCTION 11 27 0.002264 0.009242
1137 CALCIUM DEPENDENT CELL CELL ADHESION VIA PLASMA MEMBRANE CELL ADHESION MOLECULES 11 27 0.002264 0.009242
1138 NEGATIVE REGULATION OF AXON GUIDANCE 11 27 0.002264 0.009242
1139 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 11 27 0.002264 0.009242
1140 SUBSTRATE DEPENDENT CELL MIGRATION 11 27 0.002264 0.009242
1141 POSITIVE REGULATION OF DNA REPLICATION 25 86 0.002274 0.009263
1142 REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 23 77 0.002272 0.009263
1143 NEGATIVE REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 17 51 0.002294 0.009329
1144 CELLULAR RESPONSE TO FATTY ACID 17 51 0.002294 0.009329
1145 RESPONSE TO RADIATION 90 413 0.002315 0.009409
1146 NEGATIVE REGULATION OF TRANSPORTER ACTIVITY 20 64 0.002378 0.009654
1147 REGULATION OF IMMUNE EFFECTOR PROCESS 92 424 0.002384 0.009672
1148 ORGANIC ANION TRANSPORT 85 387 0.002388 0.009678
1149 REGULATION OF CARBOHYDRATE METABOLIC PROCESS 43 172 0.002435 0.00986
1150 SPHINGOLIPID METABOLIC PROCESS 36 138 0.002453 0.009924
1151 CELL FATE DETERMINATION 15 43 0.002467 0.009975
1152 HIPPOCAMPUS DEVELOPMENT 22 73 0.002475 0.009987
1153 REGULATION OF PLASMA MEMBRANE ORGANIZATION 22 73 0.002475 0.009987
NumGOOverlapSizeP ValueAdj. P Value
1 CYTOSKELETAL PROTEIN BINDING 238 819 1.431e-20 1.329e-17
2 ENZYME BINDING 427 1737 3.008e-20 1.397e-17
3 RECEPTOR BINDING 372 1476 1.564e-19 4.843e-17
4 ACTIN BINDING 135 393 1.41e-18 3.276e-16
5 KINASE ACTIVITY 233 842 2.49e-17 4.626e-15
6 MACROMOLECULAR COMPLEX BINDING 344 1399 2.286e-16 3.54e-14
7 PROTEIN COMPLEX BINDING 249 935 3.049e-16 4.047e-14
8 MOLECULAR FUNCTION REGULATOR 334 1353 3.628e-16 4.213e-14
9 PROTEIN KINASE ACTIVITY 185 640 5.813e-16 6e-14
10 PROTEIN DOMAIN SPECIFIC BINDING 180 624 1.817e-15 1.688e-13
11 KINASE BINDING 174 606 8.671e-15 7.323e-13
12 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 101 303 2.643e-13 2.046e-11
13 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 82 228 4.967e-13 3.549e-11
14 GROWTH FACTOR BINDING 54 123 5.59e-13 3.709e-11
15 CELL ADHESION MOLECULE BINDING 71 186 6.623e-13 4.102e-11
16 CALCIUM ION BINDING 187 697 8.87e-13 5.15e-11
17 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 246 992 2.376e-12 1.299e-10
18 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 104 328 3.922e-12 2.024e-10
19 GLYCOSAMINOGLYCAN BINDING 74 205 5.468e-12 2.673e-10
20 CALMODULIN BINDING 67 179 8.331e-12 3.87e-10
21 REGULATORY REGION NUCLEIC ACID BINDING 206 818 3.686e-11 1.631e-09
22 SULFUR COMPOUND BINDING 78 234 1.342e-10 5.668e-09
23 NUCLEOSIDE TRIPHOSPHATASE REGULATOR ACTIVITY 100 329 1.504e-10 6.074e-09
24 IDENTICAL PROTEIN BINDING 280 1209 2.206e-10 8.539e-09
25 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 164 629 2.505e-10 9.31e-09
26 HEPARIN BINDING 58 157 3.721e-10 1.33e-08
27 LIPID BINDING 169 657 4.062e-10 1.398e-08
28 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 37 81 6.149e-10 2.04e-08
29 PROTEIN DIMERIZATION ACTIVITY 263 1149 2.687e-09 8.607e-08
30 PHOSPHOLIPID BINDING 103 360 3.284e-09 1.017e-07
31 ION CHANNEL BINDING 44 111 3.906e-09 1.171e-07
32 SH3 DOMAIN BINDING 45 116 5.814e-09 1.688e-07
33 PROTEIN TYROSINE KINASE ACTIVITY 60 176 6.752e-09 1.901e-07
34 ENZYME ACTIVATOR ACTIVITY 125 471 1.128e-08 3.082e-07
35 PROTEIN HOMODIMERIZATION ACTIVITY 176 722 1.357e-08 3.597e-07
36 PHOSPHATIDYLINOSITOL BINDING 65 200 1.394e-08 3.597e-07
37 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 91 315 1.603e-08 4.025e-07
38 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 267 1199 3.037e-08 7.234e-07
39 ENZYME REGULATOR ACTIVITY 221 959 3e-08 7.234e-07
40 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 70 226 3.579e-08 8.313e-07
41 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 29 64 5.391e-08 1.221e-06
42 INTEGRIN BINDING 40 105 7.202e-08 1.556e-06
43 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 146 588 7.121e-08 1.556e-06
44 RIBONUCLEOTIDE BINDING 387 1860 9.187e-08 1.94e-06
45 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 30 70 1.484e-07 3.063e-06
46 BINDING BRIDGING 56 173 1.585e-07 3.201e-06
47 TRANSCRIPTION FACTOR BINDING 131 524 2.213e-07 4.374e-06
48 ACTIN FILAMENT BINDING 43 121 2.394e-07 4.633e-06
49 TRANSITION METAL ION BINDING 299 1400 2.861e-07 5.424e-06
50 TRANSFORMING GROWTH FACTOR BETA BINDING 12 16 3.513e-07 6.527e-06
51 ZINC ION BINDING 252 1155 4.503e-07 8.202e-06
52 GROWTH FACTOR RECEPTOR BINDING 44 129 6.525e-07 1.144e-05
53 PROTEIN SERINE THREONINE KINASE ACTIVITY 113 445 6.51e-07 1.144e-05
54 RECEPTOR SIGNALING PROTEIN ACTIVITY 54 172 7.795e-07 1.341e-05
55 SMAD BINDING 29 72 1.146e-06 1.935e-05
56 BETA CATENIN BINDING 32 84 1.417e-06 2.35e-05
57 CYTOKINE BINDING 34 92 1.52e-06 2.477e-05
58 PROTEIN KINASE A BINDING 20 42 2.391e-06 3.83e-05
59 CATION CHANNEL ACTIVITY 80 298 2.918e-06 4.595e-05
60 DOUBLE STRANDED DNA BINDING 173 764 3.073e-06 4.758e-05
61 ADENYL NUCLEOTIDE BINDING 313 1514 3.159e-06 4.811e-05
62 PHOSPHORIC ESTER HYDROLASE ACTIVITY 94 368 4.237e-06 6.348e-05
63 COLLAGEN BINDING 26 65 4.714e-06 6.952e-05
64 METALLOENDOPEPTIDASE ACTIVITY 38 113 5.397e-06 7.834e-05
65 RHO GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 29 77 5.671e-06 8.105e-05
66 METAL ION TRANSMEMBRANE TRANSPORTER ACTIVITY 103 417 7.43e-06 0.0001046
67 GATED CHANNEL ACTIVITY 84 325 8.312e-06 0.0001152
68 INSULIN RECEPTOR BINDING 16 32 1.116e-05 0.0001525
69 SEQUENCE SPECIFIC DNA BINDING 221 1037 1.263e-05 0.00017
70 EXTRACELLULAR MATRIX STRUCTURAL CONSTITUENT 28 76 1.328e-05 0.0001763
71 ACTIVATING TRANSCRIPTION FACTOR BINDING 23 57 1.388e-05 0.0001816
72 PASSIVE TRANSMEMBRANE TRANSPORTER ACTIVITY 111 464 1.558e-05 0.000201
73 CORE PROMOTER PROXIMAL REGION DNA BINDING 92 371 1.892e-05 0.0002375
74 PLATELET DERIVED GROWTH FACTOR RECEPTOR BINDING 10 15 1.868e-05 0.0002375
75 VOLTAGE GATED ION CHANNEL ACTIVITY 54 190 2.065e-05 0.0002558
76 PROTEIN COMPLEX SCAFFOLD 25 68 3.95e-05 0.0004733
77 PHOSPHATASE BINDING 47 162 3.914e-05 0.0004733
78 FIBRONECTIN BINDING 14 28 3.974e-05 0.0004733
79 CORE PROMOTER SEQUENCE SPECIFIC DNA BINDING 33 101 4.233e-05 0.0004977
80 HORMONE BINDING 24 65 5.166e-05 0.0005999
81 PLATELET DERIVED GROWTH FACTOR BINDING 8 11 5.343e-05 0.0006128
82 SODIUM CHANNEL REGULATOR ACTIVITY 15 32 5.527e-05 0.0006262
83 PHOSPHORIC DIESTER HYDROLASE ACTIVITY 30 90 6.105e-05 0.0006595
84 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II DISTAL ENHANCER SEQUENCE SPECIFIC BINDING 30 90 6.105e-05 0.0006595
85 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 40 133 5.949e-05 0.0006595
86 PDZ DOMAIN BINDING 30 90 6.105e-05 0.0006595
87 METALLOPEPTIDASE ACTIVITY 52 188 6.412e-05 0.0006847
88 ACTININ BINDING 14 29 6.525e-05 0.0006889
89 GLUCOCORTICOID RECEPTOR BINDING 9 14 7.68e-05 0.0008017
90 VOLTAGE GATED SODIUM CHANNEL ACTIVITY 11 20 8.908e-05 0.0009195
91 SCAFFOLD PROTEIN BINDING 18 45 0.0001343 0.001371
92 CORE PROMOTER BINDING 43 152 0.0001532 0.001547
93 WNT PROTEIN BINDING 14 31 0.0001611 0.001592
94 ALPHA ACTININ BINDING 11 21 0.0001594 0.001592
95 X3 5 CYCLIC AMP PHOSPHODIESTERASE ACTIVITY 9 15 0.000164 0.001604
96 SIGNALING ADAPTOR ACTIVITY 25 74 0.0001915 0.001853
97 CHANNEL REGULATOR ACTIVITY 38 131 0.0002064 0.001976
98 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 32 105 0.0002386 0.002261
99 X1 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 17 43 0.0002423 0.002274
100 EXTRACELLULAR MATRIX BINDING 19 51 0.0002661 0.002472
101 STEROID HORMONE RECEPTOR ACTIVITY 21 59 0.0002703 0.002486
102 NITRIC OXIDE SYNTHASE BINDING 10 19 0.0003039 0.002741
103 PROLINE RICH REGION BINDING 10 19 0.0003039 0.002741
104 PROTEIN KINASE A REGULATORY SUBUNIT BINDING 9 16 0.0003203 0.002815
105 PROTEIN PHOSPHATASE BINDING 35 120 0.0003212 0.002815
106 PHOSPHOLIPID TRANSLOCATING ATPASE ACTIVITY 9 16 0.0003203 0.002815
107 PHOSPHOLIPID TRANSPORTER ACTIVITY 18 48 0.0003488 0.003028
108 PROTEIN HETERODIMERIZATION ACTIVITY 105 468 0.0003649 0.003139
109 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 45 168 0.0004186 0.003568
110 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II ACTIVATING TRANSCRIPTION FACTOR BINDING 19 53 0.0004698 0.003932
111 RNA POLYMERASE II CORE PROMOTER SEQUENCE SPECIFIC DNA BINDING 19 53 0.0004698 0.003932
112 CHROMATIN BINDING 98 435 0.0004846 0.004019
113 GROWTH FACTOR ACTIVITY 43 160 0.0005145 0.00423
114 SULFURIC ESTER HYDROLASE ACTIVITY 9 17 0.0005817 0.00474
115 NEUREXIN FAMILY PROTEIN BINDING 8 14 0.0006095 0.004924
116 TRANSCRIPTION COREPRESSOR ACTIVITY 55 221 0.0007544 0.00599
117 TRANSCRIPTION COACTIVATOR ACTIVITY 70 296 0.0007523 0.00599
118 PHOSPHATIDYLINOSITOL PHOSPHATE BINDING 33 116 0.0007612 0.005993
119 PHOSPHATIDYLINOSITOL KINASE ACTIVITY 18 51 0.0008128 0.006346
120 HISTONE ACETYLTRANSFERASE BINDING 12 28 0.0008441 0.006535
121 GUANYL NUCLEOTIDE BINDING 88 390 0.0008664 0.006652
122 SIGNAL TRANSDUCER ACTIVITY 331 1731 0.0009058 0.006897
123 SYNTAXIN 1 BINDING 9 18 0.0009946 0.007512
124 RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 30 104 0.00101 0.00757
125 PEPTIDE HORMONE BINDING 14 36 0.001024 0.007612
126 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE ACTIVITY 11 25 0.001064 0.007779
127 INSULIN LIKE GROWTH FACTOR BINDING 11 25 0.001064 0.007779
128 RECEPTOR SERINE THREONINE KINASE BINDING 8 15 0.001119 0.007934
129 NEUROPILIN BINDING 8 15 0.001119 0.007934
130 INSULIN LIKE GROWTH FACTOR RECEPTOR BINDING 8 15 0.001119 0.007934
131 GTPASE BINDING 69 295 0.001115 0.007934
132 ARYLSULFATASE ACTIVITY 7 12 0.001163 0.008188
133 RHO GTPASE BINDING 24 78 0.001175 0.008205
134 PROTEIN C TERMINUS BINDING 47 186 0.001247 0.008647
135 DIVALENT INORGANIC CATION TRANSMEMBRANE TRANSPORTER ACTIVITY 43 167 0.00132 0.009084
136 RECEPTOR SIGNALING PROTEIN SERINE THREONINE KINASE ACTIVITY 27 92 0.00133 0.009085
137 VIRUS RECEPTOR ACTIVITY 22 70 0.001361 0.009226
NumGOOverlapSizeP ValueAdj. P Value
1 SYNAPSE 246 754 3.736e-29 2.182e-26
2 CELL JUNCTION 332 1151 6.969e-28 2.035e-25
3 CELL PROJECTION 462 1786 6.362e-27 1.238e-24
4 NEURON PROJECTION 282 942 1.813e-26 2.349e-24
5 MEMBRANE REGION 324 1134 2.011e-26 2.349e-24
6 NEURON PART 347 1265 8.298e-25 8.077e-23
7 EXTRACELLULAR MATRIX 152 426 1.308e-22 1.091e-20
8 PROTEINACEOUS EXTRACELLULAR MATRIX 134 356 1.763e-22 1.287e-20
9 INTRINSIC COMPONENT OF PLASMA MEMBRANE 412 1649 6.88e-21 4.464e-19
10 MEMBRANE MICRODOMAIN 111 288 9.286e-20 5.423e-18
11 POSTSYNAPSE 133 378 2.475e-19 1.314e-17
12 SYNAPSE PART 187 610 5.046e-19 2.456e-17
13 ANCHORING JUNCTION 157 489 3.334e-18 1.498e-16
14 DENDRITE 147 451 9.04e-18 3.771e-16
15 SOMATODENDRITIC COMPARTMENT 192 650 1.359e-17 5.292e-16
16 PLASMA MEMBRANE REGION 251 929 3.43e-17 1.252e-15
17 CELL LEADING EDGE 121 350 4.989e-17 1.714e-15
18 CELL SURFACE 213 757 8.749e-17 2.839e-15
19 PLASMA MEMBRANE PROTEIN COMPLEX 154 510 3.05e-15 9.374e-14
20 CELL SUBSTRATE JUNCTION 128 398 3.869e-15 1.13e-13
21 EXCITATORY SYNAPSE 78 197 4.761e-15 1.324e-13
22 EXTRACELLULAR MATRIX COMPONENT 57 125 1.699e-14 4.511e-13
23 ACTIN CYTOSKELETON 135 444 9.003e-14 2.286e-12
24 CELL CELL JUNCTION 119 383 5.269e-13 1.282e-11
25 AXON 125 418 2.693e-12 6.29e-11
26 I BAND 52 121 4.096e-12 9.2e-11
27 GOLGI APPARATUS 331 1445 1.738e-11 3.758e-10
28 FILOPODIUM 43 94 2.41e-11 5.027e-10
29 CONTRACTILE FIBER 74 211 2.691e-11 5.42e-10
30 INTERCALATED DISC 29 51 5.532e-11 1.077e-09
31 SARCOLEMMA 51 125 6.714e-11 1.265e-09
32 SYNAPTIC MEMBRANE 85 261 7.831e-11 1.429e-09
33 CELL CELL CONTACT ZONE 33 64 9.323e-11 1.601e-09
34 CELL BODY 137 494 9.323e-11 1.601e-09
35 CELL PROJECTION PART 230 946 9.726e-11 1.623e-09
36 CYTOSKELETON 424 1967 1.78e-10 2.888e-09
37 BASEMENT MEMBRANE 40 93 1.16e-09 1.797e-08
38 INTRACELLULAR VESICLE 286 1259 1.169e-09 1.797e-08
39 T TUBULE 25 45 2.289e-09 3.427e-08
40 LAMELLIPODIUM 60 172 2.493e-09 3.64e-08
41 RECEPTOR COMPLEX 95 327 5.722e-09 8.15e-08
42 ACTIN BASED CELL PROJECTION 61 181 8.331e-09 1.158e-07
43 SITE OF POLARIZED GROWTH 53 149 9.679e-09 1.315e-07
44 PERINUCLEAR REGION OF CYTOPLASM 160 642 1.286e-08 1.707e-07
45 PLASMA MEMBRANE RAFT 36 86 1.844e-08 2.394e-07
46 CELL CORTEX 73 238 2.89e-08 3.669e-07
47 POSTSYNAPTIC MEMBRANE 65 205 4.056e-08 4.935e-07
48 SIDE OF MEMBRANE 114 428 4e-08 4.935e-07
49 CYTOPLASMIC REGION 83 287 6.408e-08 7.637e-07
50 CYTOPLASMIC SIDE OF MEMBRANE 55 170 2.077e-07 2.412e-06
51 COMPLEX OF COLLAGEN TRIMERS 15 23 2.107e-07 2.412e-06
52 PLATELET ALPHA GRANULE 31 75 2.487e-07 2.793e-06
53 CATION CHANNEL COMPLEX 54 167 2.721e-07 2.943e-06
54 AXON PART 66 219 2.694e-07 2.943e-06
55 EXTRINSIC COMPONENT OF MEMBRANE 73 252 3.619e-07 3.843e-06
56 ENDOPLASMIC RETICULUM LUMEN 61 201 5.765e-07 6.012e-06
57 NEURON SPINE 42 121 6.824e-07 6.991e-06
58 EXTRINSIC COMPONENT OF CYTOPLASMIC SIDE OF PLASMA MEMBRANE 36 98 8.951e-07 9.013e-06
59 APICAL JUNCTION COMPLEX 43 128 1.384e-06 1.37e-05
60 COLLAGEN TRIMER 33 88 1.476e-06 1.437e-05
61 LEADING EDGE MEMBRANE 44 134 2.107e-06 2.017e-05
62 CELL CORTEX PART 40 119 3.13e-06 2.948e-05
63 EXTRINSIC COMPONENT OF PLASMA MEMBRANE 44 136 3.283e-06 3.043e-05
64 ENDOPLASMIC RETICULUM 334 1631 3.497e-06 3.191e-05
65 NEUROMUSCULAR JUNCTION 23 54 4.695e-06 4.218e-05
66 CORTICAL ACTIN CYTOSKELETON 24 58 5.4e-06 4.778e-05
67 RUFFLE 48 156 5.806e-06 5.061e-05
68 A BAND 17 34 5.929e-06 5.092e-05
69 ACTIN FILAMENT 27 70 7.019e-06 5.941e-05
70 VOLTAGE GATED SODIUM CHANNEL COMPLEX 10 14 7.305e-06 6.094e-05
71 TRANSPORTER COMPLEX 83 321 9.225e-06 7.588e-05
72 VACUOLE 248 1180 1.062e-05 8.617e-05
73 MEMBRANE PROTEIN COMPLEX 217 1020 1.702e-05 0.0001362
74 CELL CELL ADHERENS JUNCTION 22 54 1.773e-05 0.0001399
75 ACTOMYOSIN 24 62 2.085e-05 0.0001623
76 GLYCOPROTEIN COMPLEX 12 21 2.519e-05 0.0001886
77 M BAND 12 21 2.519e-05 0.0001886
78 PLATELET ALPHA GRANULE LUMEN 22 55 2.5e-05 0.0001886
79 EXTRACELLULAR SPACE 280 1376 3.661e-05 0.0002706
80 GOLGI APPARATUS PART 191 893 3.939e-05 0.0002875
81 CORTICAL CYTOSKELETON 28 81 5.105e-05 0.0003681
82 ENDOSOME 171 793 6.327e-05 0.0004506
83 NEURON PROJECTION TERMINUS 39 129 6.442e-05 0.0004532
84 PLASMA MEMBRANE RECEPTOR COMPLEX 49 175 7.359e-05 0.0005116
85 INTERSTITIAL MATRIX 9 14 7.68e-05 0.0005277
86 SODIUM CHANNEL COMPLEX 10 17 8.791e-05 0.000597
87 APICAL PART OF CELL 87 361 9.387e-05 0.0006301
88 CYTOSKELETAL PART 287 1436 0.0001109 0.0007363
89 NEURONAL POSTSYNAPTIC DENSITY 20 53 0.0001509 0.0009899
90 PROTEIN KINASE COMPLEX 29 90 0.0001584 0.001016
91 POTASSIUM CHANNEL COMPLEX 29 90 0.0001584 0.001016
92 MAIN AXON 21 58 0.0002055 0.001305
93 COATED PIT 23 67 0.0002609 0.001638
94 NEURON PROJECTION MEMBRANE 15 36 0.0002828 0.001757
95 COSTAMERE 10 19 0.0003039 0.001868
96 CELL PROJECTION MEMBRANE 72 298 0.0003322 0.002
97 PRESYNAPSE 69 283 0.0003318 0.002
98 CYTOPLASMIC VESICLE PART 130 601 0.0004023 0.002397
99 MYELIN SHEATH 45 168 0.0004186 0.00247
100 EARLY ENDOSOME 72 301 0.0004524 0.002642
101 TRANSCRIPTION FACTOR COMPLEX 71 298 0.0005557 0.003213
102 FIBRIL 8 14 0.0006095 0.003456
103 AXOLEMMA 8 14 0.0006095 0.003456
104 BASOLATERAL PLASMA MEMBRANE 53 211 0.0007398 0.004154
105 BASAL PART OF CELL 18 51 0.0008128 0.004521
106 SECRETORY GRANULE LUMEN 26 85 0.0008264 0.004553
107 SARCOPLASM 22 68 0.000885 0.00483
108 TERMINAL BOUTON 21 64 0.0009351 0.005056
109 FILOPODIUM MEMBRANE 9 18 0.0009946 0.005329
110 SECRETORY GRANULE 80 352 0.001165 0.006127
111 BANDED COLLAGEN FIBRIL 7 12 0.001163 0.006127
112 PRESYNAPTIC ACTIVE ZONE 12 29 0.001227 0.006397
113 ENDOPLASMIC RETICULUM PART 229 1163 0.001247 0.006444
114 ACTIN FILAMENT BUNDLE 19 57 0.001301 0.006666
115 MICROTUBULE CYTOSKELETON 211 1068 0.001615 0.00813
116 SECRETORY VESICLE 100 461 0.001607 0.00813
117 PROTEIN COMPLEX INVOLVED IN CELL ADHESION 12 30 0.001743 0.008698

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Focal_adhesion_hsa04510 82 199 5.928e-17 3.082e-15
2 MAPK_signaling_pathway_hsa04010 98 295 7.513e-13 1.954e-11
3 cGMP_PKG_signaling_pathway_hsa04022 62 163 2.241e-11 3.885e-10
4 PI3K_Akt_signaling_pathway_hsa04151 107 352 3.424e-11 4.452e-10
5 Rap1_signaling_pathway_hsa04015 68 206 3.173e-09 2.559e-08
6 Cell_adhesion_molecules_.CAMs._hsa04514 53 145 3.245e-09 2.559e-08
7 cAMP_signaling_pathway_hsa04024 66 198 3.445e-09 2.559e-08
8 Regulation_of_actin_cytoskeleton_hsa04810 67 208 1.255e-08 8.157e-08
9 Ras_signaling_pathway_hsa04014 72 232 2.099e-08 1.106e-07
10 FoxO_signaling_pathway_hsa04068 48 132 2.127e-08 1.106e-07
11 Calcium_signaling_pathway_hsa04020 60 182 2.76e-08 1.305e-07
12 Phospholipase_D_signaling_pathway_hsa04072 51 146 3.62e-08 1.569e-07
13 Apelin_signaling_pathway_hsa04371 47 137 2.265e-07 9.061e-07
14 Hippo_signaling_pathway_hsa04390 51 154 2.513e-07 9.333e-07
15 Wnt_signaling_pathway_hsa04310 48 146 7.114e-07 2.466e-06
16 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 45 139 2.503e-06 8.134e-06
17 Adherens_junction_hsa04520 28 72 3.959e-06 1.211e-05
18 TGF_beta_signaling_pathway_hsa04350 31 84 4.486e-06 1.296e-05
19 Sphingolipid_signaling_pathway_hsa04071 39 118 6.548e-06 1.792e-05
20 ECM_receptor_interaction_hsa04512 30 82 7.787e-06 2.024e-05
21 Phosphatidylinositol_signaling_system_hsa04070 34 99 9.891e-06 2.449e-05
22 AMPK_signaling_pathway_hsa04152 38 121 3.156e-05 7.46e-05
23 Gap_junction_hsa04540 30 88 3.781e-05 8.549e-05
24 Cytokine_cytokine_receptor_interaction_hsa04060 69 270 7.445e-05 0.0001613
25 mTOR_signaling_pathway_hsa04150 42 151 0.000271 0.0005638
26 Tight_junction_hsa04530 46 170 0.0002842 0.0005683
27 ErbB_signaling_pathway_hsa04012 27 85 0.0003407 0.0006562
28 Hedgehog_signaling_pathway_hsa04340 17 47 0.0008183 0.00152
29 Cellular_senescence_hsa04218 42 160 0.0009922 0.001779
30 Hippo_signaling_pathway_multiple_species_hsa04392 12 29 0.001227 0.002127
31 Jak_STAT_signaling_pathway_hsa04630 42 162 0.001292 0.002167
32 HIF_1_signaling_pathway_hsa04066 28 100 0.002375 0.003859
33 TNF_signaling_pathway_hsa04668 29 108 0.003931 0.006194
34 Phagosome_hsa04145 38 152 0.00419 0.006409
35 Apoptosis_hsa04210 35 138 0.004565 0.006782
36 Autophagy_animal_hsa04140 31 128 0.01433 0.0207
37 VEGF_signaling_pathway_hsa04370 16 59 0.02524 0.03547
38 Oocyte_meiosis_hsa04114 29 124 0.02729 0.03734
39 Mitophagy_animal_hsa04137 17 65 0.03017 0.04022
40 Endocytosis_hsa04144 51 244 0.03695 0.04803
41 ABC_transporters_hsa02010 12 45 0.05457 0.06921
42 NF_kappa_B_signaling_pathway_hsa04064 21 95 0.08912 0.1103
43 p53_signaling_pathway_hsa04115 15 68 0.1368 0.1654
44 Neuroactive_ligand_receptor_interaction_hsa04080 51 278 0.2092 0.2472
45 Apoptosis_multiple_species_hsa04215 7 33 0.2908 0.336
46 Ferroptosis_hsa04216 8 40 0.3291 0.3721
47 Necroptosis_hsa04217 29 164 0.3587 0.3969
48 Notch_signaling_pathway_hsa04330 8 48 0.54 0.585
49 Autophagy_other_hsa04136 5 32 0.6205 0.6585
50 Cell_cycle_hsa04110 18 124 0.7498 0.7798
51 Lysosome_hsa04142 17 123 0.8134 0.8294
52 Peroxisome_hsa04146 10 83 0.8927 0.8927

Quest ID: ef11549dfb84c38c68a7263d54a95206