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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-125a-5p ABAT -0.94 0.0005 -2.12 0 miRanda -0.21 0.00301 NA
2 hsa-miR-200c-3p ABAT -0.13 0.68619 -2.12 0 MirTarget -0.29 0 NA
3 hsa-miR-361-5p ABCA10 0.24 0.24184 -1.07 4.0E-5 miRanda; mirMAP -0.34 0.01707 NA
4 hsa-miR-181b-5p ABCA5 0.47 0.05409 -0.11 0.48581 mirMAP -0.26 0 NA
5 hsa-miR-361-5p ABCA8 0.24 0.24184 -2.94 0 miRanda -0.56 0.01408 NA
6 hsa-miR-125a-5p ABCB11 -0.94 0.0005 -2.54 0 miRanda -0.52 0.00011 NA
7 hsa-miR-125a-5p ABCB8 -0.94 0.0005 0.29 0.05894 miRanda -0.1 0.00026 NA
8 hsa-miR-590-3p ABCC10 -0.47 0.00017 1.41 0 MirTarget; PITA; miRanda; miRNATAP -0.12 0.02878 NA
9 hsa-miR-125a-5p ABHD1 -0.94 0.0005 -1.22 0.00019 miRanda -0.29 0.00176 NA
10 hsa-miR-181b-5p ABHD13 0.47 0.05409 -0.67 0 MirTarget -0.11 0.00024 NA
11 hsa-miR-125a-5p ABHD14B -0.94 0.0005 -0.86 1.0E-5 miRanda -0.15 7.0E-5 NA
12 hsa-miR-181b-5p ABHD15 0.47 0.05409 -1.28 0 mirMAP -0.44 0 NA
13 hsa-miR-361-5p ABHD2 0.24 0.24184 -1.21 0 PITA; mirMAP -0.32 0.0002 NA
14 hsa-miR-125a-5p ABHD6 -0.94 0.0005 -1.27 0 MirTarget; PITA; miRanda; miRNATAP -0.16 0.00073 NA
15 hsa-miR-181b-5p ABTB2 0.47 0.05409 -0.4 0.01115 MirTarget; miRNATAP -0.34 0 NA
16 hsa-miR-125a-5p ACACB -0.94 0.0005 -1.5 0 miRanda -0.17 0.00103 NA
17 hsa-miR-361-5p ACACB 0.24 0.24184 -1.5 0 miRanda -0.33 0.00123 NA
18 hsa-miR-181b-5p ACAD8 0.47 0.05409 -0.51 7.0E-5 MirTarget -0.15 0 NA
19 hsa-miR-361-5p ACAD8 0.24 0.24184 -0.51 7.0E-5 miRanda -0.17 0.00111 NA
20 hsa-miR-200c-3p ACADSB -0.13 0.68619 -2.07 0 mirMAP -0.14 0.00013 NA
21 hsa-miR-361-5p ACBD5 0.24 0.24184 -0.74 1.0E-5 miRanda -0.22 0.00056 NA
22 hsa-miR-590-3p ACBD6 -0.47 0.00017 1.02 0 miRanda -0.21 1.0E-5 NA
23 hsa-miR-200c-3p ACE2 -0.13 0.68619 -2.26 0 miRNATAP -0.23 0.00499 NA
24 hsa-miR-15a-5p ACOX1 0.36 0.07466 -1.13 0 miRNATAP -0.3 2.0E-5 NA
25 hsa-miR-125a-5p ACP6 -0.94 0.0005 0.51 0.00021 miRanda -0.24 0 NA
26 hsa-miR-590-3p ACP6 -0.47 0.00017 0.51 0.00021 miRanda -0.2 0.00013 NA
27 hsa-miR-181b-5p ACSL1 0.47 0.05409 -2.28 0 MirTarget -0.69 0 NA
28 hsa-miR-181b-5p ACSL6 0.47 0.05409 0.45 0.19422 miRNATAP -0.75 0 NA
29 hsa-miR-125a-5p ACSM2A -0.94 0.0005 -2.16 0 miRanda -0.47 1.0E-5 NA
30 hsa-miR-125a-5p ACSM2B -0.94 0.0005 -1.65 1.0E-5 miRanda -0.54 0 NA
31 hsa-miR-181b-5p ACSS3 0.47 0.05409 -1.17 0.00039 MirTarget -1 0 NA
32 hsa-miR-590-3p ACTG2 -0.47 0.00017 2.02 0 miRanda -0.36 0.00266 NA
33 hsa-miR-590-3p ACTR1A -0.47 0.00017 0.16 0.31873 miRanda; mirMAP -0.1 0.00077 NA
34 hsa-miR-181b-5p ACVR1C 0.47 0.05409 -2.2 0 miRNATAP -0.67 0 NA
35 hsa-miR-361-5p ACY1 0.24 0.24184 -1 0 miRanda -0.18 0.04755 NA
36 hsa-miR-361-5p ADAM12 0.24 0.24184 0.87 0.00424 miRanda -0.4 0.01814 NA
37 hsa-miR-361-5p ADAM19 0.24 0.24184 -0.34 0.03922 miRanda -0.18 0.02067 NA
38 hsa-miR-361-5p ADAM28 0.24 0.24184 -0.51 0.10431 mirMAP -0.66 0.00016 NA
39 hsa-miR-590-3p ADAM33 -0.47 0.00017 0.03 0.90803 miRanda -0.49 8.0E-5 NA
40 hsa-miR-590-3p ADAMTS16 -0.47 0.00017 1.66 0.00064 miRanda; mirMAP -0.51 0.01835 NA
41 hsa-miR-15a-5p ADAMTS5 0.36 0.07466 -0.18 0.31668 miRNATAP -0.2 0.0134 NA
42 hsa-miR-590-3p ADAMTSL1 -0.47 0.00017 -0.67 0.00424 miRanda; mirMAP -0.35 0.00064 NA
43 hsa-miR-15a-5p ADAMTSL3 0.36 0.07466 -1.87 0 MirTarget -0.47 0.00098 NA
44 hsa-miR-590-3p ADCK2 -0.47 0.00017 0.54 9.0E-5 miRNATAP -0.11 0.01118 NA
45 hsa-miR-181b-5p ADCY1 0.47 0.05409 -2.69 0 miRNATAP -0.49 9.0E-5 NA
46 hsa-miR-15a-5p ADCY5 0.36 0.07466 -1.83 0 MirTarget; miRNATAP -0.63 5.0E-5 NA
47 hsa-miR-590-3p ADCY6 -0.47 0.00017 1.24 0 miRanda -0.14 0.00293 NA
48 hsa-miR-590-3p ADCY8 -0.47 0.00017 -0.06 0.90123 miRanda -0.51 0.00994 NA
49 hsa-miR-181b-5p ADCY9 0.47 0.05409 -0.1 0.51835 miRNATAP -0.14 7.0E-5 24269684 miR 181b promotes cell proliferation and reduces apoptosis by repressing the expression of adenylyl cyclase 9 AC9 in cervical cancer cells; Phenotypic experiments indicated that miR-181b and AC9 exerted opposite effects on cell proliferation and apoptosis
50 hsa-miR-125a-5p ADH1B -0.94 0.0005 -3.16 0 miRanda -0.37 0.00178 NA
51 hsa-miR-125a-5p ADH5 -0.94 0.0005 -0.51 0.00738 miRanda -0.12 2.0E-5 NA
52 hsa-miR-125a-5p ADHFE1 -0.94 0.0005 -1.3 0 miRanda -0.27 3.0E-5 NA
53 hsa-miR-181b-5p ADM 0.47 0.05409 -1.27 0 MirTarget; miRNATAP -0.18 0.00297 NA
54 hsa-miR-361-5p ADRA2A 0.24 0.24184 -0.82 0.01489 miRanda -0.85 0 NA
55 hsa-miR-125a-5p AEN -0.94 0.0005 0.28 0.06385 miRanda -0.13 2.0E-5 NA
56 hsa-miR-590-3p AEN -0.47 0.00017 0.28 0.06385 miRanda -0.1 0.04044 NA
57 hsa-miR-590-3p AFAP1 -0.47 0.00017 0.29 0.14736 PITA; miRanda; miRNATAP -0.15 0.04982 NA
58 hsa-miR-590-3p AFF3 -0.47 0.00017 -0.33 0.29 PITA; miRanda; mirMAP; miRNATAP -0.31 0.02331 NA
59 hsa-miR-15a-5p AFF4 0.36 0.07466 -0.63 0.00014 MirTarget; miRNATAP -0.18 5.0E-5 NA
60 hsa-miR-181b-5p AFF4 0.47 0.05409 -0.63 0.00014 mirMAP; miRNATAP -0.14 1.0E-5 NA
61 hsa-miR-361-5p AFF4 0.24 0.24184 -0.63 0.00014 miRanda -0.17 0.00107 NA
62 hsa-miR-181b-5p AFG3L2 0.47 0.05409 -0.28 0.0593 MirTarget; miRNATAP -0.14 0 NA
63 hsa-miR-125a-5p AGBL5 -0.94 0.0005 0.72 0 miRanda -0.1 0.00063 NA
64 hsa-miR-125a-5p AGFG2 -0.94 0.0005 -0.01 0.96903 mirMAP -0.19 0 NA
65 hsa-miR-181b-5p AGFG2 0.47 0.05409 -0.01 0.96903 mirMAP -0.19 0 NA
66 hsa-miR-181b-5p AGGF1 0.47 0.05409 0.15 0.21882 mirMAP -0.12 0 NA
67 hsa-miR-181b-5p AGPAT3 0.47 0.05409 -0.16 0.35295 MirTarget -0.11 0.00016 NA
68 hsa-miR-125a-5p AGXT2 -0.94 0.0005 -2.84 0 miRanda -0.31 0.00604 NA
69 hsa-miR-15a-5p AHCYL2 0.36 0.07466 -0.17 0.21116 miRNATAP -0.11 0.02413 NA
70 hsa-miR-590-3p AHSA2 -0.47 0.00017 1.4 0 miRanda -0.14 0.02926 NA
71 hsa-miR-125a-5p AIFM1 -0.94 0.0005 -0.37 0.03968 miRanda -0.14 0 NA
72 hsa-miR-361-5p AKAP12 0.24 0.24184 -1.39 0 miRanda -0.47 0.00176 NA
73 hsa-miR-15a-5p AKIRIN1 0.36 0.07466 -0.73 0 miRNATAP -0.14 0.0021 NA
74 hsa-miR-181b-5p AKR1C1 0.47 0.05409 -0.11 0.73604 mirMAP -0.52 0 NA
75 hsa-miR-15a-5p AKT3 0.36 0.07466 -0.7 0.00051 miRNAWalker2 validate; miRTarBase; miRNATAP -0.27 0.00291 NA
76 hsa-miR-361-5p ALDH1L2 0.24 0.24184 0.4 0.07308 miRanda; mirMAP; miRNATAP -0.43 0.00051 NA
77 hsa-miR-125a-5p ALDH6A1 -0.94 0.0005 -2.53 0 miRanda -0.18 0.01817 NA
78 hsa-let-7a-3p ALDH7A1 -0.58 0.00018 -0.71 0.00039 mirMAP -0.14 0.0475 NA
79 hsa-miR-590-3p ALG5 -0.47 0.00017 -0.05 0.70675 PITA; miRanda; miRNATAP -0.12 0.00275 NA
80 hsa-miR-590-3p ALKBH2 -0.47 0.00017 0.61 6.0E-5 miRanda -0.24 5.0E-5 NA
81 hsa-miR-200c-3p AMFR -0.13 0.68619 -0.44 0.02246 miRNATAP -0.13 0 NA
82 hsa-miR-361-5p AMFR 0.24 0.24184 -0.44 0.02246 miRanda -0.16 0.00434 NA
83 hsa-miR-125a-5p AMIGO3 -0.94 0.0005 2.01 0 mirMAP -0.27 0 NA
84 hsa-miR-15a-5p AMOTL1 0.36 0.07466 -0.56 0.03513 MirTarget; miRNATAP -0.36 0.0013 NA
85 hsa-miR-125a-5p AMPD2 -0.94 0.0005 0.1 0.52929 miRanda -0.12 1.0E-5 NA
86 hsa-miR-125a-5p ANGPT2 -0.94 0.0005 1.15 0 miRanda -0.16 0.002 NA
87 hsa-miR-361-5p ANKFY1 0.24 0.24184 -0.59 5.0E-5 miRanda -0.15 0.00135 NA
88 hsa-miR-125a-5p ANKMY1 -0.94 0.0005 0.48 1.0E-5 miRanda -0.14 0 NA
89 hsa-miR-361-5p ANKRD17 0.24 0.24184 -0.34 0.03784 miRanda -0.13 0.02124 NA
90 hsa-miR-125a-5p ANKRD29 -0.94 0.0005 1.14 4.0E-5 MirTarget; miRanda -0.19 0.01399 NA
91 hsa-miR-15a-5p ANKRD29 0.36 0.07466 1.14 4.0E-5 MirTarget -0.46 0.00045 NA
92 hsa-miR-590-3p ANKRD29 -0.47 0.00017 1.14 4.0E-5 mirMAP -0.48 9.0E-5 NA
93 hsa-miR-361-5p ANKRD44 0.24 0.24184 -0.65 0.00123 miRanda -0.3 0.00667 NA
94 hsa-miR-181b-5p ANKRD50 0.47 0.05409 -0.26 0.08715 MirTarget; miRNATAP -0.11 0.00648 NA
95 hsa-let-7a-3p ANKRD52 -0.58 0.00018 1.45 0 mirMAP -0.13 0.02173 NA
96 hsa-miR-125a-5p ANKZF1 -0.94 0.0005 0.84 0 miRanda -0.15 0 NA
97 hsa-miR-361-5p ANO1 0.24 0.24184 -2.22 0 miRanda; miRNATAP -0.63 0.00053 NA
98 hsa-miR-590-3p ANXA2 -0.47 0.00017 1.09 2.0E-5 miRanda -0.25 0.00042 NA
99 hsa-miR-590-3p ANXA9 -0.47 0.00017 0 0.99029 miRanda -0.15 0.04543 NA
100 hsa-miR-361-5p AOC3 0.24 0.24184 -0.86 0 MirTarget; miRanda -0.29 9.0E-5 NA
101 hsa-miR-181b-5p AP1G1 0.47 0.05409 -0.48 0.00251 miRNATAP -0.14 0 NA
102 hsa-let-7a-3p AP3B1 -0.58 0.00018 0.63 1.0E-5 mirMAP -0.17 0 NA
103 hsa-miR-125a-5p APC2 -0.94 0.0005 1.71 0 mirMAP -0.2 0.0003 NA
104 hsa-miR-181b-5p API5 0.47 0.05409 -0.32 0.02833 MirTarget -0.16 0 NA
105 hsa-miR-15a-5p APLNR 0.36 0.07466 -1 0.00021 MirTarget -0.45 0.00013 NA
106 hsa-miR-590-3p APOBEC3F -0.47 0.00017 -0.43 0.02722 miRanda -0.17 0.03855 NA
107 hsa-miR-590-3p APOE -0.47 0.00017 -0.16 0.61559 miRanda -0.18 0.03508 NA
108 hsa-miR-361-5p APOLD1 0.24 0.24184 0.44 0.03044 miRanda -0.19 0.04563 NA
109 hsa-miR-590-3p APOO -0.47 0.00017 0.32 0.01554 miRanda -0.12 0.00795 NA
110 hsa-miR-15a-5p APP 0.36 0.07466 -0.65 0.01331 miRNAWalker2 validate; miRNATAP -0.18 0.01826 NA
111 hsa-miR-125a-5p AQP6 -0.94 0.0005 -0.81 0.08152 miRanda -0.3 0.01877 NA
112 hsa-miR-181b-5p AR 0.47 0.05409 -2.61 0 miRNATAP -1.3 0 NA
113 hsa-miR-590-3p ARAP3 -0.47 0.00017 0.11 0.49888 mirMAP -0.19 0.00225 NA
114 hsa-miR-125a-5p ARFGAP2 -0.94 0.0005 -0.04 0.80196 miRanda -0.11 0 NA
115 hsa-miR-181b-5p ARFGEF2 0.47 0.05409 0.05 0.77461 MirTarget; miRNATAP -0.11 0.00402 NA
116 hsa-miR-361-5p ARHGAP15 0.24 0.24184 -1.12 0 miRanda -0.48 0 NA
117 hsa-miR-361-5p ARHGAP20 0.24 0.24184 -2.19 0 miRanda -0.59 0.00012 NA
118 hsa-miR-361-5p ARHGAP31 0.24 0.24184 -0.44 0.00674 mirMAP -0.44 0 NA
119 hsa-miR-181b-5p ARHGAP32 0.47 0.05409 -0.2 0.16295 mirMAP -0.15 0.00021 NA
120 hsa-miR-361-5p ARHGAP42 0.24 0.24184 -1.23 0 miRanda -0.21 0.02495 NA
121 hsa-miR-15a-5p ARHGAP5 0.36 0.07466 -0.39 0.01205 MirTarget; miRNATAP -0.14 0.00276 NA
122 hsa-miR-181b-5p ARHGAP5 0.47 0.05409 -0.39 0.01205 mirMAP -0.16 0 NA
123 hsa-miR-361-5p ARHGAP6 0.24 0.24184 0.19 0.277 PITA; miRanda -0.4 2.0E-5 NA
124 hsa-miR-361-5p ARHGAP9 0.24 0.24184 -0.68 0.00172 miRanda -0.34 0.00306 NA
125 hsa-miR-590-3p ARHGEF10 -0.47 0.00017 0 0.98927 miRanda; mirMAP -0.21 0.00587 NA
126 hsa-miR-15a-5p ARHGEF12 0.36 0.07466 -0.87 1.0E-5 MirTarget -0.28 0 NA
127 hsa-miR-361-5p ARHGEF12 0.24 0.24184 -0.87 1.0E-5 miRNATAP -0.26 2.0E-5 NA
128 hsa-miR-590-3p ARHGEF15 -0.47 0.00017 0.52 0.00084 miRanda; mirMAP -0.3 0 NA
129 hsa-miR-590-3p ARHGEF3 -0.47 0.00017 0.5 0.01168 mirMAP -0.17 0.03465 NA
130 hsa-miR-590-3p ARHGEF37 -0.47 0.00017 1.11 1.0E-5 mirMAP -0.25 0.0252 NA
131 hsa-miR-361-5p ARHGEF6 0.24 0.24184 -0.59 0.00036 miRanda -0.25 0.00243 NA
132 hsa-miR-181b-5p ARIH1 0.47 0.05409 -0.13 0.35122 MirTarget; mirMAP -0.13 0 NA
133 hsa-miR-361-5p ARL10 0.24 0.24184 -0.43 0.01336 mirMAP -0.22 0.01897 NA
134 hsa-miR-15a-5p ARMCX2 0.36 0.07466 -0.64 0.00116 MirTarget; miRNATAP -0.31 0.00064 NA
135 hsa-miR-590-3p ARPC1A -0.47 0.00017 0.54 0.00137 PITA; miRanda -0.11 0.00241 NA
136 hsa-miR-590-3p ARPC5 -0.47 0.00017 0.69 0.00013 miRanda -0.1 0.00352 NA
137 hsa-miR-200c-3p ARPP21 -0.13 0.68619 -2.21 0 MirTarget; miRNATAP -0.18 0.00835 NA
138 hsa-miR-361-5p ARRB1 0.24 0.24184 -0.71 0.00034 MirTarget; miRanda -0.3 0.00301 NA
139 hsa-miR-361-5p ARRDC2 0.24 0.24184 0.69 0.00284 miRanda -0.38 0.00021 NA
140 hsa-miR-181b-5p ARRDC3 0.47 0.05409 -0.7 0.00035 MirTarget; mirMAP; miRNATAP -0.2 7.0E-5 NA
141 hsa-let-7a-3p ARSB -0.58 0.00018 0.01 0.95979 mirMAP -0.22 0.00013 NA
142 hsa-miR-590-3p ARSE -0.47 0.00017 -0.38 0.38002 miRanda -0.61 0.0007 NA
143 hsa-miR-590-3p ARV1 -0.47 0.00017 0.37 0.00397 miRanda -0.14 0.00061 NA
144 hsa-miR-125a-5p ASB13 -0.94 0.0005 -0.75 2.0E-5 miRanda; miRNATAP -0.1 0.01053 NA
145 hsa-miR-181b-5p ASB13 0.47 0.05409 -0.75 2.0E-5 miRNAWalker2 validate -0.38 0 NA
146 hsa-miR-590-3p ASNA1 -0.47 0.00017 0.58 0.00013 miRanda -0.15 5.0E-5 NA
147 hsa-miR-181b-5p ASPA 0.47 0.05409 -2.87 0 mirMAP -0.46 0 NA
148 hsa-miR-125a-5p ASPH -0.94 0.0005 0.47 0.04375 miRanda -0.11 0.0256 NA
149 hsa-miR-15a-5p ASTN1 0.36 0.07466 -1.43 0 MirTarget -0.46 0.00044 NA
150 hsa-let-7a-3p ASTN2 -0.58 0.00018 0.18 0.19895 mirMAP -0.2 0.00126 NA
NumGOOverlapSizeP ValueAdj. P Value
1 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 309 1977 3.171e-16 1.475e-12
2 ORGANONITROGEN COMPOUND METABOLIC PROCESS 284 1796 1.427e-15 3.32e-12
3 CARDIOVASCULAR SYSTEM DEVELOPMENT 151 788 3.557e-15 4.138e-12
4 CIRCULATORY SYSTEM DEVELOPMENT 151 788 3.557e-15 4.138e-12
5 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 181 1021 1.363e-14 1.269e-11
6 RESPONSE TO ENDOGENOUS STIMULUS 235 1450 4.019e-14 3.117e-11
7 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 258 1656 2.022e-13 1.344e-10
8 POSITIVE REGULATION OF MOLECULAR FUNCTION 273 1791 4.858e-13 2.825e-10
9 VASCULATURE DEVELOPMENT 99 469 6.729e-13 3.479e-10
10 SMALL MOLECULE METABOLIC PROCESS 269 1767 8.607e-13 4.005e-10
11 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 170 1008 7.212e-12 3.051e-09
12 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 213 1360 2.053e-11 7.962e-09
13 ORGANOPHOSPHATE METABOLIC PROCESS 151 885 4.837e-11 1.731e-08
14 CELL MOTILITY 144 835 6.392e-11 1.983e-08
15 LOCALIZATION OF CELL 144 835 6.392e-11 1.983e-08
16 NUCLEOBASE CONTAINING SMALL MOLECULE METABOLIC PROCESS 103 535 7.52e-11 2.187e-08
17 BLOOD VESSEL MORPHOGENESIS 78 364 8.952e-11 2.314e-08
18 RESPONSE TO OXYGEN CONTAINING COMPOUND 213 1381 8.595e-11 2.314e-08
19 PURINE CONTAINING COMPOUND METABOLIC PROCESS 82 394 1.363e-10 3.338e-08
20 PHOSPHORYLATION 193 1228 1.475e-10 3.431e-08
21 INTRACELLULAR SIGNAL TRANSDUCTION 235 1572 1.776e-10 3.935e-08
22 NEGATIVE REGULATION OF CELL COMMUNICATION 188 1192 1.946e-10 4.115e-08
23 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 267 1848 3.126e-10 6.06e-08
24 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 246 1672 3.041e-10 6.06e-08
25 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 160 983 4.819e-10 8.969e-08
26 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 136 799 5.453e-10 9.47e-08
27 ORGANONITROGEN COMPOUND BIOSYNTHETIC PROCESS 165 1024 5.495e-10 9.47e-08
28 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 196 1275 6.962e-10 1.141e-07
29 REGULATION OF TRANSPORT 260 1804 7.113e-10 1.141e-07
30 REGULATION OF CELL DEATH 220 1472 7.47e-10 1.159e-07
31 RESPONSE TO NITROGEN COMPOUND 143 859 9.163e-10 1.375e-07
32 CATABOLIC PROCESS 255 1773 1.305e-09 1.898e-07
33 NEUROGENESIS 210 1402 1.575e-09 2.221e-07
34 POSITIVE REGULATION OF CATALYTIC ACTIVITY 224 1518 1.625e-09 2.224e-07
35 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 209 1395 1.696e-09 2.255e-07
36 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 258 1805 1.879e-09 2.428e-07
37 NEGATIVE REGULATION OF CELL DEATH 143 872 2.559e-09 3.218e-07
38 LOCOMOTION 173 1114 3.552e-09 4.349e-07
39 POSITIVE REGULATION OF HYDROLASE ACTIVITY 146 905 5.279e-09 6.298e-07
40 RESPONSE TO GROWTH FACTOR 89 475 5.897e-09 6.859e-07
41 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 175 1142 7.792e-09 8.843e-07
42 CELLULAR CATABOLIC PROCESS 197 1322 8.031e-09 8.898e-07
43 RESPONSE TO OXYGEN LEVELS 65 311 9.284e-09 1.005e-06
44 ESTABLISHMENT OF LOCALIZATION IN CELL 239 1676 9.999e-09 1.057e-06
45 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 216 1492 1.644e-08 1.7e-06
46 REGULATION OF HYDROLASE ACTIVITY 196 1327 1.763e-08 1.764e-06
47 REGULATION OF CELL MORPHOGENESIS 98 552 1.781e-08 1.764e-06
48 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 140 876 2.013e-08 1.952e-06
49 POSITIVE REGULATION OF GENE EXPRESSION 244 1733 2.141e-08 2.033e-06
50 POSITIVE REGULATION OF CELL COMMUNICATION 220 1532 2.343e-08 2.18e-06
51 REGULATION OF CELL DIFFERENTIATION 215 1492 2.602e-08 2.374e-06
52 REGULATION OF CELLULAR COMPONENT MOVEMENT 126 771 2.874e-08 2.572e-06
53 ANGIOGENESIS 61 293 3.059e-08 2.686e-06
54 RESPONSE TO ABIOTIC STIMULUS 156 1024 7.817e-08 6.735e-06
55 RESPONSE TO INORGANIC SUBSTANCE 86 479 7.962e-08 6.736e-06
56 NEGATIVE REGULATION OF TRANSPORT 83 458 8.827e-08 7.334e-06
57 CHEMICAL HOMEOSTASIS 137 874 9.376e-08 7.419e-06
58 HEART DEVELOPMENT 84 466 9.407e-08 7.419e-06
59 OXIDATION REDUCTION PROCESS 140 898 9.407e-08 7.419e-06
60 REGULATION OF LIPID METABOLIC PROCESS 58 282 1.033e-07 8.008e-06
61 RESPONSE TO OXIDATIVE STRESS 68 352 1.101e-07 8.402e-06
62 RESPONSE TO REACTIVE OXYGEN SPECIES 44 191 1.281e-07 9.61e-06
63 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 245 1784 1.695e-07 1.252e-05
64 REGULATION OF VASCULATURE DEVELOPMENT 50 233 1.978e-07 1.438e-05
65 REGULATION OF PHOSPHORUS METABOLIC PROCESS 225 1618 2.189e-07 1.567e-05
66 TISSUE DEVELOPMENT 213 1518 2.434e-07 1.716e-05
67 POSITIVE REGULATION OF CELL DEATH 101 605 2.486e-07 1.726e-05
68 REGULATION OF MAPK CASCADE 108 660 2.668e-07 1.822e-05
69 CELLULAR MACROMOLECULE LOCALIZATION 179 1234 2.702e-07 1.822e-05
70 REGULATION OF LIPID BIOSYNTHETIC PROCESS 33 128 3.063e-07 2.036e-05
71 CAMP METABOLIC PROCESS 15 34 3.128e-07 2.05e-05
72 POSITIVE REGULATION OF LOCOMOTION 76 420 3.257e-07 2.105e-05
73 CYCLIC NUCLEOTIDE METABOLIC PROCESS 20 57 3.329e-07 2.122e-05
74 MACROMOLECULE CATABOLIC PROCESS 141 926 3.48e-07 2.188e-05
75 REGULATION OF EPITHELIAL CELL PROLIFERATION 57 285 3.535e-07 2.193e-05
76 PROTEIN PHOSPHORYLATION 143 944 3.893e-07 2.384e-05
77 REGULATION OF GTPASE ACTIVITY 109 673 3.957e-07 2.391e-05
78 REGULATION OF KINASE ACTIVITY 122 776 4.102e-07 2.447e-05
79 CELLULAR RESPONSE TO NITROGEN COMPOUND 87 505 4.336e-07 2.554e-05
80 REGULATION OF CELL PROLIFERATION 209 1496 4.407e-07 2.563e-05
81 REGULATION OF CELL DEVELOPMENT 129 836 5.393e-07 3.098e-05
82 RESPONSE TO HORMONE 136 893 5.59e-07 3.172e-05
83 NEGATIVE REGULATION OF PROTEIN SECRETION 29 108 6.283e-07 3.522e-05
84 POSITIVE REGULATION OF TRANSPORT 141 936 6.498e-07 3.599e-05
85 REGULATION OF DENDRITE DEVELOPMENT 31 120 6.597e-07 3.611e-05
86 POSITIVE REGULATION OF RESPONSE TO STIMULUS 258 1929 7.175e-07 3.838e-05
87 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 45 209 7.176e-07 3.838e-05
88 SPROUTING ANGIOGENESIS 17 45 7.578e-07 4.007e-05
89 REGULATION OF CELL PROJECTION ORGANIZATION 93 558 7.981e-07 4.173e-05
90 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 77 437 8.089e-07 4.182e-05
91 ENERGY DERIVATION BY OXIDATION OF ORGANIC COMPOUNDS 46 217 8.635e-07 4.367e-05
92 REGULATION OF CATABOLIC PROCESS 115 731 8.557e-07 4.367e-05
93 INTRACELLULAR PROTEIN TRANSPORT 121 781 9.891e-07 4.949e-05
94 POSITIVE REGULATION OF MAPK CASCADE 81 470 1.06e-06 5.192e-05
95 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 81 470 1.06e-06 5.192e-05
96 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 164 1135 1.12e-06 5.43e-05
97 HOMEOSTATIC PROCESS 188 1337 1.141e-06 5.473e-05
98 MITOCHONDRION ORGANIZATION 97 594 1.188e-06 5.639e-05
99 PROTEIN LOCALIZATION 242 1805 1.381e-06 6.491e-05
100 BIOLOGICAL ADHESION 151 1032 1.474e-06 6.859e-05
101 NUCLEOSIDE TRIPHOSPHATE METABOLIC PROCESS 47 228 1.518e-06 6.993e-05
102 CELLULAR RESPONSE TO HORMONE STIMULUS 91 552 1.684e-06 7.682e-05
103 ESTABLISHMENT OF PROTEIN LOCALIZATION 197 1423 1.81e-06 8.179e-05
104 SINGLE ORGANISM BIOSYNTHETIC PROCESS 187 1340 2.01e-06 8.994e-05
105 REGULATION OF PROTEIN MODIFICATION PROCESS 230 1710 2.057e-06 9.115e-05
106 CARBOHYDRATE DERIVATIVE METABOLIC PROCESS 152 1047 2.143e-06 9.406e-05
107 PROTEIN TARGETING 71 406 2.835e-06 0.0001229
108 HEAD DEVELOPMENT 110 709 2.879e-06 0.0001229
109 MUSCLE SYSTEM PROCESS 54 282 2.86e-06 0.0001229
110 POSITIVE REGULATION OF CELL PROLIFERATION 123 814 2.919e-06 0.0001235
111 POSITIVE REGULATION OF CELL DIFFERENTIATION 124 823 3.081e-06 0.0001292
112 AMEBOIDAL TYPE CELL MIGRATION 35 154 3.314e-06 0.0001377
113 REGULATION OF NEURON PROJECTION DEVELOPMENT 71 408 3.393e-06 0.0001397
114 REGULATION OF NEURON DIFFERENTIATION 90 554 3.563e-06 0.0001454
115 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 53 278 4.029e-06 0.000163
116 CIRCULATORY SYSTEM PROCESS 65 366 4.352e-06 0.0001743
117 CELLULAR RESPIRATION 33 143 4.405e-06 0.0001743
118 NUCLEAR TRANSCRIBED MRNA CATABOLIC PROCESS NONSENSE MEDIATED DECAY 29 118 4.42e-06 0.0001743
119 CYTOSKELETON ORGANIZATION 125 838 4.663e-06 0.0001823
120 ORGANIC HYDROXY COMPOUND METABOLIC PROCESS 80 482 5.439e-06 0.0002091
121 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 18 56 5.398e-06 0.0002091
122 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 120 801 5.866e-06 0.0002237
123 RESPONSE TO ORGANIC CYCLIC COMPOUND 134 917 6.224e-06 0.0002355
124 VIRAL LIFE CYCLE 54 290 6.76e-06 0.0002517
125 REGULATION OF MAP KINASE ACTIVITY 58 319 6.727e-06 0.0002517
126 PEPTIDE METABOLIC PROCESS 91 571 6.988e-06 0.0002543
127 MUSCLE HYPERTROPHY 12 28 6.994e-06 0.0002543
128 REGULATION OF FATTY ACID OXIDATION 12 28 6.994e-06 0.0002543
129 MUSCLE STRUCTURE DEVELOPMENT 73 432 7.298e-06 0.0002612
130 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 43 213 7.265e-06 0.0002612
131 NEGATIVE REGULATION OF SECRETION 41 200 7.945e-06 0.0002822
132 MESENCHYMAL CELL DIFFERENTIATION 31 134 8.038e-06 0.0002833
133 REGULATION OF ORGAN MORPHOGENESIS 47 242 8.32e-06 0.0002911
134 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 113 750 8.441e-06 0.0002931
135 REGULATION OF VASCULOGENESIS 8 13 8.561e-06 0.0002948
136 SINGLE ORGANISM CELLULAR LOCALIZATION 131 898 8.617e-06 0.0002948
137 ORGANIC CYCLIC COMPOUND CATABOLIC PROCESS 72 427 9.074e-06 0.0003082
138 CELLULAR AMIDE METABOLIC PROCESS 110 727 9.174e-06 0.0003093
139 MITOCHONDRIAL TRANSMEMBRANE TRANSPORT 18 58 9.396e-06 0.0003145
140 NEURON MIGRATION 27 110 9.56e-06 0.0003177
141 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 161 1152 9.865e-06 0.0003232
142 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 25 98 9.822e-06 0.0003232
143 POSITIVE REGULATION OF KINASE ACTIVITY 79 482 9.961e-06 0.0003241
144 MUSCLE CELL DIFFERENTIATION 46 237 1.051e-05 0.0003395
145 REGULATION OF SYSTEM PROCESS 82 507 1.13e-05 0.0003626
146 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 143 1004 1.192e-05 0.0003798
147 RESPONSE TO WOUNDING 89 563 1.214e-05 0.0003842
148 RESPONSE TO METAL ION 59 333 1.273e-05 0.0003944
149 MESENCHYME DEVELOPMENT 39 190 1.267e-05 0.0003944
150 STEM CELL DIFFERENTIATION 39 190 1.267e-05 0.0003944
151 CENTRAL NERVOUS SYSTEM DEVELOPMENT 127 872 1.28e-05 0.0003944
152 WOUND HEALING 77 470 1.305e-05 0.0003994
153 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 38 184 1.407e-05 0.0004279
154 CELL DEVELOPMENT 192 1426 1.446e-05 0.0004368
155 INTERSPECIES INTERACTION BETWEEN ORGANISMS 101 662 1.496e-05 0.0004461
156 SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM 101 662 1.496e-05 0.0004461
157 REGULATION OF PROTEIN LOCALIZATION 136 950 1.515e-05 0.0004472
158 REGULATION OF ORGANELLE ORGANIZATION 163 1178 1.519e-05 0.0004472
159 RESPONSE TO PEPTIDE 68 404 1.69e-05 0.0004854
160 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 146 1036 1.683e-05 0.0004854
161 ORGANOPHOSPHATE BIOSYNTHETIC PROCESS 74 450 1.675e-05 0.0004854
162 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 146 1036 1.683e-05 0.0004854
163 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 104 689 1.775e-05 0.0005066
164 NEGATIVE REGULATION OF GENE EXPRESSION 199 1493 1.881e-05 0.0005323
165 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 30 133 1.89e-05 0.0005323
166 REGULATION OF CELLULAR LOCALIZATION 174 1277 1.899e-05 0.0005323
167 AGING 49 264 1.932e-05 0.000535
168 REGULATION OF ENDOTHELIAL CELL MIGRATION 27 114 1.923e-05 0.000535
169 REGULATION OF CELL SUBSTRATE ADHESION 36 173 1.969e-05 0.000542
170 GLYCOSYL COMPOUND METABOLIC PROCESS 63 368 1.999e-05 0.000547
171 PROTEIN LOCALIZATION TO MEMBRANE 64 376 2.073e-05 0.0005607
172 RENAL SYSTEM PROCESS 25 102 2.071e-05 0.0005607
173 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 44 229 2.101e-05 0.0005613
174 ESTABLISHMENT OF PROTEIN LOCALIZATION TO ORGANELLE 62 361 2.097e-05 0.0005613
175 OXIDATIVE PHOSPHORYLATION 22 84 2.111e-05 0.0005613
176 REGULATION OF DENDRITIC SPINE DEVELOPMENT 17 56 2.286e-05 0.0006009
177 ORGAN MORPHOGENESIS 122 841 2.275e-05 0.0006009
178 REGULATION OF CELLULAR COMPONENT BIOGENESIS 113 767 2.317e-05 0.0006058
179 REGULATION OF MUSCLE SYSTEM PROCESS 39 195 2.369e-05 0.0006157
180 REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 26 109 2.384e-05 0.0006162
181 REGULATION OF MUSCLE ORGAN DEVELOPMENT 25 103 2.476e-05 0.0006365
182 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 19 68 2.849e-05 0.0007284
183 REGULATION OF TRANSFERASE ACTIVITY 134 946 2.932e-05 0.0007454
184 ESTABLISHMENT OF PROTEIN LOCALIZATION TO ENDOPLASMIC RETICULUM 25 104 2.951e-05 0.0007463
185 CENTRAL NERVOUS SYSTEM NEURON AXONOGENESIS 11 27 3.021e-05 0.0007599
186 REGULATION OF GROWTH 96 633 3.068e-05 0.0007675
187 RHYTHMIC PROCESS 53 298 3.088e-05 0.0007683
188 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 200 1517 3.493e-05 0.0008646
189 GENERATION OF PRECURSOR METABOLITES AND ENERGY 52 292 3.523e-05 0.0008674
190 MULTI ORGANISM METABOLIC PROCESS 30 138 3.986e-05 0.0009763
191 LIPID LOCALIZATION 48 264 4.039e-05 0.0009839
192 SYNAPSE ORGANIZATION 31 145 4.2e-05 0.001018
193 POSITIVE REGULATION OF MAP KINASE ACTIVITY 40 207 4.268e-05 0.001029
194 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 19 70 4.433e-05 0.001063
195 ELECTRON TRANSPORT CHAIN 23 94 4.497e-05 0.001073
196 REGULATION OF EPITHELIAL CELL MIGRATION 34 166 4.644e-05 0.001103
197 STRIATED MUSCLE CELL DIFFERENTIATION 35 173 4.73e-05 0.001117
198 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 134 957 5.075e-05 0.001187
199 SINGLE ORGANISM CATABOLIC PROCESS 134 957 5.075e-05 0.001187
200 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 74 465 5.135e-05 0.001195
201 REGULATION OF NEURON DEATH 46 252 5.235e-05 0.001206
202 CELLULAR RESPONSE TO PEPTIDE 49 274 5.232e-05 0.001206
203 REGULATION OF DEVELOPMENTAL GROWTH 51 289 5.327e-05 0.001221
204 ACTIN FILAMENT BASED PROCESS 72 450 5.409e-05 0.001234
205 POSITIVE REGULATION OF BINDING 28 127 5.457e-05 0.001239
206 DEVELOPMENTAL CELL GROWTH 20 77 5.608e-05 0.001267
207 REGULATION OF PROTEIN SECRETION 64 389 5.975e-05 0.001343
208 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 17 60 6.107e-05 0.001363
209 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 15 49 6.15e-05 0.001363
210 REGULATION OF STEROID BIOSYNTHETIC PROCESS 15 49 6.15e-05 0.001363
211 REGULATION OF FATTY ACID BETA OXIDATION 8 16 6.479e-05 0.001429
212 NEGATIVE REGULATION OF LIPID BIOSYNTHETIC PROCESS 14 44 6.704e-05 0.001464
213 CELL GROWTH 29 135 6.683e-05 0.001464
214 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 57 337 6.852e-05 0.00149
215 TISSUE MORPHOGENESIS 82 533 6.94e-05 0.001502
216 RESPONSE TO LIPID 125 888 7.155e-05 0.001541
217 REGULATION OF MUSCLE TISSUE DEVELOPMENT 24 103 7.216e-05 0.001547
218 REGULATION OF TRANSPORTER ACTIVITY 38 198 7.628e-05 0.001628
219 REGULATION OF HOMEOSTATIC PROCESS 71 447 7.676e-05 0.001631
220 REGULATION OF COENZYME METABOLIC PROCESS 15 50 7.972e-05 0.001663
221 LIPID HOMEOSTASIS 25 110 7.962e-05 0.001663
222 REGULATION OF RESPONSE TO STRESS 192 1468 7.963e-05 0.001663
223 REGULATION OF COFACTOR METABOLIC PROCESS 15 50 7.972e-05 0.001663
224 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 107 740 8.177e-05 0.001699
225 PROTEIN TARGETING TO MEMBRANE 32 157 8.441e-05 0.001746
226 ENDOMEMBRANE SYSTEM ORGANIZATION 73 465 8.95e-05 0.001843
227 INOSITOL LIPID MEDIATED SIGNALING 27 124 9.212e-05 0.001888
228 POSITIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 11 30 9.512e-05 0.001941
229 NEGATIVE REGULATION OF LIPID METABOLIC PROCESS 20 80 0.0001002 0.002036
230 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 65 404 0.0001034 0.002092
231 REGULATION OF CHOLESTEROL BIOSYNTHETIC PROCESS 7 13 0.0001044 0.002102
232 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 50 289 0.0001049 0.002103
233 REGULATION OF ACTIN FILAMENT BASED PROCESS 53 312 0.000108 0.002157
234 REGULATION OF OSTEOBLAST DIFFERENTIATION 25 112 0.0001085 0.002157
235 CAMP BIOSYNTHETIC PROCESS 8 17 0.0001115 0.002199
236 CYCLIC NUCLEOTIDE CATABOLIC PROCESS 8 17 0.0001115 0.002199
237 ENDOTHELIAL CELL MIGRATION 16 57 0.0001127 0.002204
238 REGULATION OF RESPONSE TO WOUNDING 66 413 0.0001126 0.002204
239 CYCLIC NUCLEOTIDE MEDIATED SIGNALING 14 46 0.0001153 0.002216
240 REGULATION OF ERK1 AND ERK2 CASCADE 43 238 0.000115 0.002216
241 PURINE CONTAINING COMPOUND BIOSYNTHETIC PROCESS 29 139 0.0001157 0.002216
242 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 82 541 0.0001157 0.002216
243 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 82 541 0.0001157 0.002216
244 TRANSLATIONAL INITIATION 30 146 0.0001189 0.002267
245 POSITIVE REGULATION OF PROTEIN KINASE B SIGNALING 20 81 0.0001206 0.00229
246 NEURAL CREST CELL DIFFERENTIATION 19 75 0.0001226 0.002318
247 POSITIVE REGULATION OF NEURON DIFFERENTIATION 52 306 0.0001236 0.002329
248 REGULATION OF VESICLE MEDIATED TRANSPORT 72 462 0.0001255 0.002348
249 REGULATION OF CYTOSKELETON ORGANIZATION 77 502 0.0001257 0.002348
250 NUCLEOSIDE MONOPHOSPHATE METABOLIC PROCESS 43 239 0.0001268 0.002361
251 REGULATION OF SECRETION 101 699 0.0001318 0.002436
252 CARDIAC MUSCLE TISSUE DEVELOPMENT 29 140 0.0001321 0.002436
253 LIPID METABOLIC PROCESS 155 1158 0.0001325 0.002436
254 CELL DIFFERENTIATION INVOLVED IN KIDNEY DEVELOPMENT 12 36 0.0001336 0.002447
255 REGULATION OF MUSCLE CONTRACTION 30 147 0.0001352 0.002467
256 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 31 154 0.0001374 0.002496
257 PROTEIN COMPLEX SUBUNIT ORGANIZATION 197 1527 0.0001391 0.002519
258 REGULATION OF ANATOMICAL STRUCTURE SIZE 73 472 0.0001438 0.002583
259 POSITIVE REGULATION OF CELL DEVELOPMENT 73 472 0.0001438 0.002583
260 POSITIVE REGULATION OF DENDRITE DEVELOPMENT 17 64 0.0001472 0.002634
261 RESPONSE TO STEROID HORMONE 76 497 0.0001529 0.002724
262 CELLULAR RESPONSE TO LIPID 71 457 0.0001534 0.002724
263 CENTRAL NERVOUS SYSTEM PROJECTION NEURON AXONOGENESIS 9 22 0.0001559 0.002738
264 REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY BY P53 CLASS MEDIATOR 9 22 0.0001559 0.002738
265 REGULATION OF CHOLESTEROL METABOLIC PROCESS 9 22 0.0001559 0.002738
266 POSITIVE REGULATION OF PROTEOLYSIS 59 363 0.0001597 0.002794
267 POSITIVE REGULATION OF LIPID METABOLIC PROCESS 27 128 0.0001617 0.002807
268 MUSCLE CELL DEVELOPMENT 27 128 0.0001617 0.002807
269 REGULATION OF BODY FLUID LEVELS 77 506 0.0001624 0.002809
270 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 76 498 0.000163 0.002809
271 ACTIVATION OF PROTEIN KINASE ACTIVITY 48 279 0.0001637 0.00281
272 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 15 53 0.0001655 0.002831
273 POSITIVE REGULATION OF CATABOLIC PROCESS 63 395 0.0001685 0.002872
274 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 25 115 0.0001693 0.002875
275 REGULATION OF EPITHELIAL CELL APOPTOTIC PROCESS 16 59 0.0001758 0.002963
276 VASCULOGENESIS 16 59 0.0001758 0.002963
277 PROTEIN LOCALIZATION TO ORGANELLE 83 556 0.0001764 0.002963
278 POSITIVE REGULATION OF HEART GROWTH 10 27 0.0001796 0.003007
279 MEMBRANE ORGANIZATION 124 899 0.0001827 0.003047
280 NEURON DIFFERENTIATION 121 874 0.0001872 0.00311
281 REGULATION OF NEURON APOPTOTIC PROCESS 36 192 0.0001886 0.003113
282 REGULATION OF PROTEIN STABILITY 40 221 0.000188 0.003113
283 POSITIVE REGULATION OF FATTY ACID OXIDATION 7 14 0.0001905 0.003122
284 CAMP CATABOLIC PROCESS 7 14 0.0001905 0.003122
285 CELLULAR RESPONSE TO OXYGEN LEVELS 29 143 0.0001944 0.003163
286 REGULATION OF CELL MATRIX ADHESION 21 90 0.0001951 0.003163
287 REGULATION OF OSSIFICATION 34 178 0.0001948 0.003163
288 PROTEIN LOCALIZATION TO ENDOPLASMIC RETICULUM 26 123 0.0002045 0.003295
289 TISSUE MIGRATION 20 84 0.0002054 0.003295
290 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 90 616 0.0002051 0.003295
291 ORGANIC ACID METABOLIC PROCESS 130 953 0.0002072 0.003313
292 WNT SIGNALING PATHWAY 57 351 0.0002092 0.003334
293 REGULATION OF MUSCLE CELL APOPTOTIC PROCESS 13 43 0.0002164 0.003425
294 CELL FATE DETERMINATION 13 43 0.0002164 0.003425
295 CELLULAR HOMEOSTASIS 97 676 0.0002285 0.003604
296 POSITIVE REGULATION OF GROWTH 42 238 0.0002331 0.003664
297 CELLULAR LIPID METABOLIC PROCESS 125 913 0.0002349 0.00368
298 NEGATIVE REGULATION OF PEPTIDE SECRETION 14 49 0.000243 0.003756
299 PROTEIN STABILIZATION 27 131 0.0002413 0.003756
300 GLOMERULUS DEVELOPMENT 14 49 0.000243 0.003756
301 REGULATION OF CHEMOTAXIS 34 180 0.0002427 0.003756
302 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 28 138 0.0002462 0.003784
303 REGULATION OF CELLULAR KETONE METABOLIC PROCESS 33 173 0.0002464 0.003784
304 NEGATIVE REGULATION OF MAPK CASCADE 29 145 0.0002493 0.003816
305 RIBONUCLEOTIDE CATABOLIC PROCESS 10 28 0.0002543 0.00388
306 ION TRANSPORT 165 1262 0.0002598 0.00395
307 REGULATION OF ORGAN GROWTH 18 73 0.0002639 0.004
308 NUCLEOSIDE PHOSPHATE BIOSYNTHETIC PROCESS 35 188 0.0002649 0.004001
309 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 41 232 0.0002664 0.004011
310 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 17 67 0.0002685 0.004018
311 STEROID HORMONE MEDIATED SIGNALING PATHWAY 26 125 0.0002679 0.004018
312 SECOND MESSENGER MEDIATED SIGNALING 31 160 0.0002812 0.004194
313 AMIDE BIOSYNTHETIC PROCESS 76 507 0.0002856 0.004232
314 REGULATION OF APOPTOTIC SIGNALING PATHWAY 58 363 0.0002855 0.004232
315 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 126 926 0.0002866 0.004234
316 REGULATION OF DENDRITE MORPHOGENESIS 18 74 0.0003163 0.004614
317 CELLULAR RESPONSE TO CARBOHYDRATE STIMULUS 18 74 0.0003163 0.004614
318 EMBRYO DEVELOPMENT 122 894 0.0003171 0.004614
319 POSITIVE REGULATION OF PEPTIDASE ACTIVITY 30 154 0.0003173 0.004614
320 DEVELOPMENTAL GROWTH 54 333 0.0003138 0.004614
321 NERVE DEVELOPMENT 17 68 0.0003248 0.004708
322 HEART MORPHOGENESIS 38 212 0.0003281 0.004712
323 NEGATIVE REGULATION OF SMOOTH MUSCLE CONTRACTION 7 15 0.0003262 0.004712
324 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 16 62 0.0003273 0.004712
325 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 58 365 0.0003298 0.004722
326 RNA CATABOLIC PROCESS 40 227 0.0003342 0.00477
327 REGULATION OF FATTY ACID METABOLIC PROCESS 20 87 0.0003385 0.00479
328 RESPONSE TO INSULIN 37 205 0.0003397 0.00479
329 CYCLIC NUCLEOTIDE BIOSYNTHETIC PROCESS 11 34 0.0003407 0.00479
330 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 22 100 0.0003401 0.00479
331 REGULATION OF ANOIKIS 9 24 0.0003401 0.00479
332 NEGATIVE REGULATION OF CELL DIFFERENTIATION 88 609 0.0003475 0.00487
333 POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 10 29 0.0003533 0.004937
334 ORGANIC HYDROXY COMPOUND TRANSPORT 30 155 0.0003562 0.004962
335 CELL DEATH 134 1001 0.0003727 0.005177
336 RESPONSE TO DRUG 66 431 0.0003869 0.005357
337 NEURON PROJECTION DEVELOPMENT 80 545 0.0003901 0.005383
338 SYNAPSE ASSEMBLY 17 69 0.000391 0.005383
339 NEGATIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 12 40 0.0004069 0.005585
340 REGULATION OF CYTOPLASMIC TRANSPORT 72 481 0.0004245 0.00581
341 NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 36 200 0.0004276 0.005834
342 RELAXATION OF MUSCLE 8 20 0.0004381 0.005943
343 INTRACELLULAR LIPID TRANSPORT 8 20 0.0004381 0.005943
344 CELLULAR PROTEIN COMPLEX DISASSEMBLY 25 122 0.0004415 0.005971
345 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 13 46 0.0004516 0.006091
346 REGULATION OF LIPID CATABOLIC PROCESS 14 52 0.0004768 0.006393
347 RESPONSE TO HYDROGEN PEROXIDE 23 109 0.0004759 0.006393
348 NEGATIVE REGULATION OF TRANSPORTER ACTIVITY 16 64 0.0004818 0.006395
349 SMOOTH MUSCLE CELL DIFFERENTIATION 10 30 0.0004824 0.006395
350 REGULATION OF CARBOHYDRATE METABOLIC PROCESS 32 172 0.0004804 0.006395
351 POSITIVE REGULATION OF ERK1 AND ERK2 CASCADE 32 172 0.0004804 0.006395
352 PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 9 25 0.0004841 0.006399
353 NEGATIVE REGULATION OF WOUND HEALING 15 58 0.0004857 0.006402
354 RESPONSE TO FIBROBLAST GROWTH FACTOR 24 116 0.0004913 0.006458
355 POSITIVE REGULATION OF EXOCYTOSIS 19 83 0.0004989 0.006521
356 CARDIOCYTE DIFFERENTIATION 21 96 0.0004979 0.006521
357 RESPONSE TO ALKALOID 27 137 0.0005105 0.006654
358 REGULATION OF CIRCADIAN RHYTHM 22 103 0.0005247 0.006801
359 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 22 103 0.0005247 0.006801
360 REGULATION OF JNK CASCADE 30 159 0.000557 0.007181
361 NEGATIVE REGULATION OF CELL PROLIFERATION 91 643 0.0005571 0.007181
362 CARTILAGE MORPHOGENESIS 6 12 0.0005653 0.007232
363 FATTY ACID HOMEOSTASIS 6 12 0.0005653 0.007232
364 REGULATION OF MUSCLE CELL DIFFERENTIATION 29 152 0.0005657 0.007232
365 PLASMA MEMBRANE ORGANIZATION 36 203 0.0005707 0.007275
366 RESPONSE TO EXTERNAL STIMULUS 225 1821 0.0005868 0.007419
367 REGULATION OF PEPTIDE TRANSPORT 43 256 0.0005854 0.007419
368 CELLULAR ALDEHYDE METABOLIC PROCESS 19 84 0.0005847 0.007419
369 ESTABLISHMENT OF PROTEIN LOCALIZATION TO MEMBRANE 44 264 0.0006023 0.007595
370 REGULATION OF BLOOD CIRCULATION 48 295 0.0006076 0.007641
371 NEGATIVE REGULATION OF PHOSPHORYLATION 64 422 0.0006095 0.007644
372 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 49 303 0.0006176 0.007725
373 REGULATION OF CELL ADHESION 89 629 0.0006415 0.008003
374 PROTEIN CATABOLIC PROCESS 83 579 0.0006464 0.00802
375 KIDNEY EPITHELIUM DEVELOPMENT 25 125 0.0006449 0.00802
376 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 35 197 0.0006524 0.008074
377 MITOCHONDRIAL ELECTRON TRANSPORT NADH TO UBIQUINONE 12 42 0.0006658 0.008195
378 AUTONOMIC NERVOUS SYSTEM DEVELOPMENT 12 42 0.0006658 0.008195
379 RESPONSE TO CARBOHYDRATE 31 168 0.0006739 0.008274
380 POSITIVE REGULATION OF LIPID BIOSYNTHETIC PROCESS 16 66 0.0006951 0.008511
381 NEGATIVE REGULATION OF COAGULATION 13 48 0.000707 0.008635
382 ZYMOGEN ACTIVATION 23 112 0.0007108 0.008658
383 REGULATION OF SMOOTH MUSCLE CONTRACTION 15 60 0.0007158 0.008697
384 DENDRITE DEVELOPMENT 18 79 0.0007358 0.008916
385 REGULATION OF BLOOD PRESSURE 31 169 0.0007471 0.009023
386 LEUKOCYTE MIGRATION 43 259 0.0007485 0.009023
387 CELLULAR RESPONSE TO OXIDATIVE STRESS 33 184 0.000774 0.009306
388 TRANSMEMBRANE TRANSPORT 143 1098 0.000779 0.009342
389 REGULATION OF GLUCOSE METABOLIC PROCESS 22 106 0.000791 0.009462
390 REGULATION OF BINDING 46 283 0.0007973 0.009512
391 NEGATIVE REGULATION OF ANOIKIS 7 17 0.000822 0.009683
392 UROGENITAL SYSTEM DEVELOPMENT 48 299 0.0008213 0.009683
393 MITOCHONDRIAL ATP SYNTHESIS COUPLED PROTON TRANSPORT 7 17 0.000822 0.009683
394 REGULATION OF PRI MIRNA TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 7 17 0.000822 0.009683
395 NEGATIVE REGULATION OF STRIATED MUSCLE CELL APOPTOTIC PROCESS 7 17 0.000822 0.009683
NumGOOverlapSizeP ValueAdj. P Value
1 ENZYME BINDING 254 1737 2.768e-10 2.571e-07
2 KINASE BINDING 105 606 2.067e-08 9.6e-06
3 CYTOSKELETAL PROTEIN BINDING 131 819 5.547e-08 1.718e-05
4 PROTEIN DOMAIN SPECIFIC BINDING 104 624 1.792e-07 4.161e-05
5 STRUCTURAL CONSTITUENT OF RIBOSOME 46 212 4.299e-07 6.656e-05
6 GROWTH FACTOR BINDING 32 123 3.688e-07 6.656e-05
7 KINASE ACTIVITY 127 842 2.211e-06 0.0002693
8 ADENYL NUCLEOTIDE BINDING 207 1514 2.319e-06 0.0002693
9 OXIDOREDUCTASE ACTIVITY 111 719 3.285e-06 0.0003391
10 IDENTICAL PROTEIN BINDING 169 1209 5.818e-06 0.0005405
11 RIBONUCLEOTIDE BINDING 244 1860 6.417e-06 0.0005419
12 NUCLEOSIDE TRIPHOSPHATASE REGULATOR ACTIVITY 59 329 8.718e-06 0.0006749
13 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 141 992 1.525e-05 0.00109
14 SULFUR COMPOUND BINDING 45 234 1.664e-05 0.001104
15 ENZYME ACTIVATOR ACTIVITY 76 471 2.535e-05 0.00157
16 OXIDOREDUCTASE ACTIVITY ACTING ON NAD P H 23 93 3.75e-05 0.002049
17 COFACTOR BINDING 48 263 3.656e-05 0.002049
18 PROTEIN C TERMINUS BINDING 37 186 4.274e-05 0.002206
19 PROTEIN HOMODIMERIZATION ACTIVITY 106 722 4.761e-05 0.002276
20 HYDROLASE ACTIVITY ACTING ON ESTER BONDS 108 739 4.901e-05 0.002276
21 TRANSLATION REPRESSOR ACTIVITY 9 20 6.35e-05 0.002809
22 TRANSLATION REGULATOR ACTIVITY 12 35 9.799e-05 0.004138
23 PROTEIN KINASE ACTIVITY 94 640 0.0001236 0.004785
24 CHAPERONE BINDING 20 81 0.0001206 0.004785
25 STEROID HORMONE RECEPTOR ACTIVITY 16 59 0.0001758 0.006505
26 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 51 303 0.000182 0.006505
27 LIPID BINDING 95 657 0.0002011 0.00692
28 COENZYME BINDING 34 179 0.0002176 0.007219
29 PHOSPHORIC ESTER HYDROLASE ACTIVITY 59 368 0.0002319 0.00743
30 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 86 588 0.0002714 0.008404
31 ADRENERGIC RECEPTOR BINDING 8 19 0.0002883 0.008639
32 TRANSCRIPTION FACTOR BINDING 78 524 0.000298 0.008649
33 PLATELET DERIVED GROWTH FACTOR BINDING 6 11 0.000309 0.008649
34 TRANSPORTER ACTIVITY 166 1276 0.0003166 0.008649
35 X3 5 CYCLIC AMP PHOSPHODIESTERASE ACTIVITY 7 15 0.0003262 0.008657
36 ZINC ION BINDING 152 1155 0.0003374 0.008707
NumGOOverlapSizeP ValueAdj. P Value
1 MITOCHONDRION 272 1633 7.271e-18 4.246e-15
2 MITOCHONDRIAL PART 171 953 2.57e-14 7.505e-12
3 NEURON PROJECTION 161 942 9.237e-12 1.798e-09
4 PERINUCLEAR REGION OF CYTOPLASM 116 642 2.892e-10 4.223e-08
5 CELL PROJECTION 257 1786 1.059e-09 1.237e-07
6 MITOCHONDRIAL ENVELOPE 120 691 1.729e-09 1.683e-07
7 DENDRITE 87 451 2.049e-09 1.71e-07
8 SOMATODENDRITIC COMPARTMENT 112 650 9.527e-09 6.955e-07
9 NEURON PART 187 1265 3.625e-08 2.352e-06
10 MITOCHONDRIAL PROTEIN COMPLEX 36 136 4.358e-08 2.545e-06
11 ENVELOPE 165 1090 4.998e-08 2.654e-06
12 MITOCHONDRIAL MATRIX 77 412 6.942e-08 3.379e-06
13 ENDOPLASMIC RETICULUM 229 1631 7.742e-08 3.478e-06
14 ANCHORING JUNCTION 86 489 2.031e-07 8.472e-06
15 RIBOSOMAL SUBUNIT 39 163 2.291e-07 8.919e-06
16 CELL JUNCTION 169 1151 2.7e-07 9.855e-06
17 ORGANELLE INNER MEMBRANE 90 525 3.441e-07 1.182e-05
18 INNER MITOCHONDRIAL MEMBRANE PROTEIN COMPLEX 29 106 4.095e-07 1.297e-05
19 CELL LEADING EDGE 66 350 4.22e-07 1.297e-05
20 RIBOSOME 48 226 4.747e-07 1.386e-05
21 CELL SUBSTRATE JUNCTION 71 398 1.354e-06 3.764e-05
22 MEMBRANE REGION 163 1134 1.665e-06 4.419e-05
23 MEMBRANE MICRODOMAIN 55 288 2.532e-06 6.429e-05
24 VACUOLE 167 1180 3.184e-06 7.438e-05
25 MITOCHONDRIAL MEMBRANE PART 38 173 3.084e-06 7.438e-05
26 AXON 72 418 4.224e-06 9.487e-05
27 LARGE RIBOSOMAL SUBUNIT 25 95 5.416e-06 0.0001171
28 ENDOSOME 119 793 5.919e-06 0.0001235
29 PLASMA MEMBRANE REGION 135 929 7.655e-06 0.0001541
30 APICAL PART OF CELL 63 361 1.079e-05 0.0002033
31 GOLGI APPARATUS 195 1445 1.071e-05 0.0002033
32 ENDOPLASMIC RETICULUM PART 162 1163 1.114e-05 0.0002034
33 OXIDOREDUCTASE COMPLEX 24 93 1.189e-05 0.0002105
34 CYTOSOLIC RIBOSOME 27 113 1.621e-05 0.0002785
35 LAMELLIPODIUM 36 172 1.724e-05 0.0002808
36 APICAL PLASMA MEMBRANE 53 292 1.731e-05 0.0002808
37 ACTIN CYTOSKELETON 73 444 1.917e-05 0.0003026
38 CYTOSOLIC PART 43 223 2.371e-05 0.0003644
39 NUCLEAR OUTER MEMBRANE ENDOPLASMIC RETICULUM MEMBRANE NETWORK 141 1005 2.934e-05 0.0004394
40 COMPACT MYELIN 8 15 3.554e-05 0.0005189
41 SYNAPSE 110 754 4.502e-05 0.0006412
42 NEURON SPINE 27 121 5.904e-05 0.0008209
43 CELL PROJECTION PART 132 946 6.77e-05 0.0009194
44 POSTSYNAPSE 62 378 8.461e-05 0.001123
45 VACUOLAR PART 101 694 0.0001002 0.001272
46 RESPIRATORY CHAIN 20 80 0.0001002 0.001272
47 EXTRACELLULAR MATRIX COMPONENT 27 125 0.0001064 0.001322
48 EXCITATORY SYNAPSE 37 197 0.0001494 0.001817
49 VACUOLAR MEMBRANE 87 587 0.0001598 0.001904
50 CELL BODY 75 494 0.0002109 0.002464
51 INTRACELLULAR VESICLE 165 1259 0.0002315 0.002651
52 CYTOSOLIC LARGE RIBOSOMAL SUBUNIT 16 61 0.0002676 0.003005
53 BASEMENT MEMBRANE 21 93 0.000316 0.003421
54 AXON PART 39 219 0.0003163 0.003421
55 CYTOSKELETON 242 1967 0.0004635 0.004921
56 LYTIC VACUOLE 77 526 0.000539 0.005621
57 MEMBRANE PROTEIN COMPLEX 135 1020 0.0005688 0.005828
58 NADH DEHYDROGENASE COMPLEX 12 42 0.0006658 0.006704
59 PLASMA MEMBRANE RAFT 19 86 0.0007951 0.00787
60 SITE OF POLARIZED GROWTH 28 149 0.0008927 0.008688
61 I BAND 24 121 0.0009255 0.008718
62 APICAL JUNCTION COMPLEX 25 128 0.0009256 0.008718
63 FILOPODIUM 20 94 0.00097 0.008992
64 CYTOPLASMIC REGION 46 287 0.001077 0.009829
65 CELL CELL JUNCTION 58 383 0.001108 0.009953

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 MAPK_signaling_pathway_hsa04010 57 295 1.138e-06 5.919e-05
2 Rap1_signaling_pathway_hsa04015 42 206 7.144e-06 0.0001626
3 PI3K_Akt_signaling_pathway_hsa04151 62 352 9.383e-06 0.0001626
4 cGMP_PKG_signaling_pathway_hsa04022 35 163 1.257e-05 0.0001634
5 mTOR_signaling_pathway_hsa04150 32 151 3.822e-05 0.0003975
6 Focal_adhesion_hsa04510 38 199 8.528e-05 0.0007391
7 HIF_1_signaling_pathway_hsa04066 23 100 0.0001248 0.0009273
8 AMPK_signaling_pathway_hsa04152 26 121 0.0001548 0.001006
9 Ras_signaling_pathway_hsa04014 41 232 0.0002664 0.001539
10 Gap_junction_hsa04540 20 88 0.0003971 0.002065
11 cAMP_signaling_pathway_hsa04024 35 198 0.0007172 0.00339
12 Apelin_signaling_pathway_hsa04371 26 137 0.001152 0.00499
13 Phospholipase_D_signaling_pathway_hsa04072 27 146 0.001399 0.005425
14 FoxO_signaling_pathway_hsa04068 25 132 0.001461 0.005425
15 Regulation_of_actin_cytoskeleton_hsa04810 35 208 0.001747 0.006056
16 Adherens_junction_hsa04520 16 72 0.001873 0.006088
17 Oocyte_meiosis_hsa04114 23 124 0.002921 0.008936
18 Autophagy_animal_hsa04140 22 128 0.008954 0.02587
19 Cellular_senescence_hsa04218 26 160 0.009974 0.0273
20 Wnt_signaling_pathway_hsa04310 24 146 0.01128 0.02933
21 VEGF_signaling_pathway_hsa04370 12 59 0.01355 0.03356
22 Apoptosis_hsa04210 22 138 0.02058 0.04863
23 ErbB_signaling_pathway_hsa04012 15 85 0.0222 0.0502
24 Necroptosis_hsa04217 25 164 0.02387 0.05172
25 Calcium_signaling_pathway_hsa04020 27 182 0.02674 0.05438
26 Sphingolipid_signaling_pathway_hsa04071 19 118 0.02719 0.05438
27 Endocytosis_hsa04144 34 244 0.03302 0.0636
28 Tight_junction_hsa04530 25 170 0.03518 0.06465
29 Hippo_signaling_pathway_hsa04390 23 154 0.03605 0.06465
30 p53_signaling_pathway_hsa04115 12 68 0.03817 0.06555
31 Phosphatidylinositol_signaling_system_hsa04070 16 99 0.03908 0.06555
32 Ferroptosis_hsa04216 8 40 0.04367 0.07096
33 Hippo_signaling_pathway_multiple_species_hsa04392 6 29 0.06588 0.102
34 ECM_receptor_interaction_hsa04512 13 82 0.06672 0.102
35 Peroxisome_hsa04146 13 83 0.07214 0.1072
36 Apoptosis_multiple_species_hsa04215 6 33 0.1094 0.1581
37 ABC_transporters_hsa02010 7 45 0.1635 0.2298
38 Hedgehog_signaling_pathway_hsa04340 7 47 0.1914 0.2619
39 TNF_signaling_pathway_hsa04668 14 108 0.1983 0.2644
40 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 17 139 0.2362 0.3071
41 Lysosome_hsa04142 15 123 0.2574 0.3265
42 Phagosome_hsa04145 18 152 0.2716 0.3363
43 Cell_adhesion_molecules_.CAMs._hsa04514 16 145 0.3918 0.4738
44 Autophagy_other_hsa04136 4 32 0.4065 0.4804
45 Jak_STAT_signaling_pathway_hsa04630 17 162 0.4702 0.5433
46 Mitophagy_animal_hsa04137 7 65 0.4874 0.5459
47 NF_kappa_B_signaling_pathway_hsa04064 10 95 0.4934 0.5459
48 Cytokine_cytokine_receptor_interaction_hsa04060 25 270 0.7052 0.764
49 Neuroactive_ligand_receptor_interaction_hsa04080 24 278 0.8182 0.8683
50 TGF_beta_signaling_pathway_hsa04350 6 84 0.8629 0.8926
51 Notch_signaling_pathway_hsa04330 3 48 0.8754 0.8926
52 Cell_cycle_hsa04110 8 124 0.941 0.941

Quest ID: f3591a8f8fd14bd31a60a1f7951995fa