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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-21-5p AKT2 1.51 0 -0.34 1.0E-5 miRNAWalker2 validate -0.25 0 NA
2 hsa-miR-330-5p AKT2 0.44 0.00533 -0.34 1.0E-5 miRanda -0.1 1.0E-5 NA
3 hsa-miR-342-3p AKT2 -0.32 0.04498 -0.34 1.0E-5 mirMAP -0.12 0 NA
4 hsa-miR-106b-5p AKT3 0.65 0 -0.66 0.00047 miRNATAP -0.26 0.00148 NA
5 hsa-miR-107 AKT3 0.24 0.01708 -0.66 0.00047 PITA; miRanda -0.6 0 NA
6 hsa-miR-122-5p AKT3 -1.24 0 -0.66 0.00047 miRNAWalker2 validate; miRTarBase -0.28 0 24244539 miR 122 regulates tumorigenesis in hepatocellular carcinoma by targeting AKT3; Here we identify AKT3 as a novel and direct target of miR-122; Restoration of miR-122 expression in HCC cell lines decreases AKT3 levels inhibits cell migration and proliferation and induces apoptosis; These anti-tumor phenotypes can be rescued by reconstitution of AKT3 expression indicating the essential role of AKT3 in miR-122 mediated HCC transformation; Our data strongly suggest that miR-122 is a tumor suppressor that targets AKT3 to regulate tumorigenesis in HCCs and a potential therapeutic candidate for liver cancer
7 hsa-miR-146b-5p AKT3 0.42 0.04574 -0.66 0.00047 miRNAWalker2 validate -0.16 0.00026 NA
8 hsa-miR-15a-5p AKT3 0.35 0.00077 -0.66 0.00047 miRNAWalker2 validate; miRTarBase; miRNATAP -0.27 0.00291 NA
9 hsa-miR-17-3p AKT3 0.41 0.00422 -0.66 0.00047 miRNATAP -0.35 0 NA
10 hsa-miR-17-5p AKT3 0.7 2.0E-5 -0.66 0.00047 TargetScan; miRNATAP -0.29 0 NA
11 hsa-miR-20a-5p AKT3 0.85 0 -0.66 0.00047 miRNATAP -0.29 0 NA
12 hsa-miR-32-3p AKT3 0.22 0.20722 -0.66 0.00047 mirMAP -0.23 4.0E-5 NA
13 hsa-miR-33a-3p AKT3 -0.68 1.0E-5 -0.66 0.00047 mirMAP -0.23 0.0001 NA
14 hsa-miR-362-3p AKT3 0.81 0 -0.66 0.00047 miRanda -0.22 0.00083 NA
15 hsa-miR-362-5p AKT3 0.72 2.0E-5 -0.66 0.00047 PITA; TargetScan; miRNATAP -0.15 0.00734 NA
16 hsa-miR-374a-5p AKT3 0.02 0.86978 -0.66 0.00047 mirMAP -0.28 0.00294 NA
17 hsa-miR-502-3p AKT3 0.66 0 -0.66 0.00047 miRNATAP -0.26 0.0008 NA
18 hsa-miR-616-5p AKT3 0.15 0.40284 -0.66 0.00047 mirMAP -0.2 0.0001 NA
19 hsa-miR-93-5p AKT3 1.4 0 -0.66 0.00047 miRNATAP -0.28 1.0E-5 NA
20 hsa-miR-125a-5p ANGPT2 -0.91 0 1.15 0 miRanda -0.16 0.002 NA
21 hsa-miR-142-5p ANGPT2 -1.45 0 1.15 0 MirTarget -0.18 0.00013 NA
22 hsa-miR-145-5p ANGPT2 -1.48 0 1.15 0 MirTarget; miRNATAP -0.2 6.0E-5 24384875; 27570490 miR 145 functions as tumor suppressor and targets two oncogenes ANGPT2 and NEDD9 in renal cell carcinoma; We further validated those miR-145 targets two oncogenes ANGPT2 and NEDD9 in RCC;MiR 145 functions as a tumor suppressor via regulating angiopoietin 2 in pancreatic cancer cells; The direct action of miR-145 on Ang-2 was predicted by TargetScan and confirmed by luciferase report assay; The expression level of miR-145 was significantly lower and the expression levels of Ang-2 mRNA and protein was significantly higher in the more aggressive pancreatic cancer cells MiaPaCa-2 and Panc-1 when compared to that in BxPC3 cells; Overexpression of miR-145 in the BxPC3 MiaPaCa-2 and Panc-1 cells suppressed the cell invasion and colony formation ability and the expression level of Ang-2 protein in MiaPaCa-2 and Panc-1 cells was also suppressed after pre-miR-145 transfection; Intratumoral delivery of miR-145 inhibited the growth of pancreatic cancer xenografts and angiogenesis in vivo and also suppressed the expression level of angiopoietin-2 protein; MiR-145 functions as a tumor suppressor in pancreatic cancer cells by targeting Ang-2 for translation repression and thus suppresses pancreatic cancer cell invasion and growth which suggests that restoring of miR-145 may be a potential therapeutic target for pancreatic cancer
23 hsa-miR-335-3p ANGPT2 -0.28 0.10663 1.15 0 mirMAP -0.16 0.00304 NA
24 hsa-miR-429 ANGPT2 -1.4 7.0E-5 1.15 0 miRanda -0.1 0.00014 NA
25 hsa-miR-542-3p ANGPT2 -1.31 0 1.15 0 MirTarget; miRanda; miRNATAP -0.36 0 NA
26 hsa-miR-744-3p ANGPT2 -0.87 0 1.15 0 MirTarget -0.15 0.00937 NA
27 hsa-miR-21-5p ATF2 1.51 0 -0.24 0.15619 miRNAWalker2 validate -0.18 0.00336 NA
28 hsa-miR-30b-5p ATF2 -0.54 2.0E-5 -0.24 0.15619 mirMAP -0.22 0.00045 NA
29 hsa-miR-103a-3p BCL2 0.77 0 -0.35 0.02497 miRNAWalker2 validate -0.28 4.0E-5 NA
30 hsa-miR-130b-5p BCL2 0.17 0.33761 -0.35 0.02497 mirMAP -0.17 7.0E-5 27364335 The level of microRNA-130b in relationship with the expression of PPARγ VEGF-A BCL-2 and apoptosis were analyzed in 91 lung cancer patient samples using immunohistochemistry and terminal deoxynucleotidyl transferase dUTP nick end labeling TUNEL assay on tissue microarrays; In vitro and in vivo miR-130b enrichment associated with down-regulation of PPARγ up-regulation of VEGF-A and BCL-2 and decreased apoptosis
31 hsa-miR-148a-3p BCL2 -0.75 0 -0.35 0.02497 miRNAWalker2 validate; miRTarBase -0.31 0 21455217; 23975374 MiR 148a promotes apoptosis by targeting Bcl 2 in colorectal cancer;MiR 148a regulates the growth and apoptosis in pancreatic cancer by targeting CCKBR and Bcl 2; Using western blot and luciferase activity assay CCKBR and Bcl-2 were identified as targets of miR-148a; Moreover we also found that the expression of Bcl-2 lacking in 3'UTR could abrogate the pro-apoptosis function of miR-148a
32 hsa-miR-17-5p BCL2 0.7 2.0E-5 -0.35 0.02497 miRNAWalker2 validate; miRTarBase -0.31 0 25435430 Combined overexpression of miR-16 and miR-17 greatly reduced Beclin-1 and Bcl-2 expressions respectively; miR-17 overexpression reduced cytoprotective autophagy by targeting Beclin-1 whereas overexpression of miR-16 potentiated paclitaxel induced apoptotic cell death by inhibiting anti-apoptotic protein Bcl-2
33 hsa-miR-186-5p BCL2 -0.06 0.53529 -0.35 0.02497 mirMAP -0.25 0.00125 NA
34 hsa-miR-192-5p BCL2 -0.5 0.00345 -0.35 0.02497 miRNAWalker2 validate -0.34 0 26550150 MicroRNA 192 regulates chemo resistance of lung adenocarcinoma for gemcitabine and cisplatin combined therapy by targeting Bcl 2; In this paper we try to test whether miR-192 regulates chemo-resistance in human carcinoma A549 mice model by targeting Bcl-2; MTT assay real-time RT-PCR western blotting assay were used to investigate miR-192 expression levels cell viability ratio and Bcl-2 protein expression levels; Bcl-2 mRNA and protein expression levels up-regulated in miR-192 inhibitor treated tumor; Bcl-2 is a key regulator for miR-192 related chemotherapy resistance; In this study we demonstrate that miR-192 regulates chemoresistance for gemcitabine and cisplatin combined chemotherapy in human adenocarcinoma lung cancer A549 cells and Bcl-2 is the target of miR-192
35 hsa-miR-20a-3p BCL2 -0.32 0.04679 -0.35 0.02497 mirMAP -0.24 0 NA
36 hsa-miR-20a-5p BCL2 0.85 0 -0.35 0.02497 miRNAWalker2 validate; miRTarBase -0.31 0 NA
37 hsa-miR-32-3p BCL2 0.22 0.20722 -0.35 0.02497 mirMAP -0.2 1.0E-5 NA
38 hsa-miR-365a-3p BCL2 0.16 0.15325 -0.35 0.02497 miRNAWalker2 validate; miRTarBase -0.33 0 NA
39 hsa-miR-455-5p BCL2 -0.27 0.05813 -0.35 0.02497 mirMAP -0.19 0.00037 NA
40 hsa-miR-590-5p BCL2 -0.1 0.31003 -0.35 0.02497 miRanda -0.29 0.00011 NA
41 hsa-miR-616-5p BCL2 0.15 0.40284 -0.35 0.02497 mirMAP -0.28 0 NA
42 hsa-miR-618 BCL2 0.14 0.51715 -0.35 0.02497 mirMAP -0.21 0 NA
43 hsa-miR-330-5p BCL2L1 0.44 0.00533 0.02 0.82745 PITA; miRanda; miRNATAP -0.15 0 NA
44 hsa-miR-342-3p BCL2L1 -0.32 0.04498 0.02 0.82745 PITA; miRanda; miRNATAP -0.12 8.0E-5 NA
45 hsa-miR-342-5p BCL2L1 -0.78 0 0.02 0.82745 miRNATAP -0.11 0.00084 NA
46 hsa-miR-484 BCL2L1 0.09 0.45398 0.02 0.82745 miRNAWalker2 validate -0.21 0 NA
47 hsa-miR-140-5p BCL2L11 -0.22 0.01407 -0.23 0.06884 miRanda -0.19 0.00626 NA
48 hsa-miR-362-5p BCL2L11 0.72 2.0E-5 -0.23 0.06884 PITA -0.12 0.00096 NA
49 hsa-miR-107 BDNF 0.24 0.01708 0.05 0.83189 MirTarget; PITA; miRanda; miRNATAP -0.55 0 27498977 MicroRNA 107 inhibits tumor growth and metastasis by targeting the BDNF mediated PI3K/AKT pathway in human non small lung cancer; In addition BDNF expression was upregulated and inversely correlated with miR-107 in NSCLC tissues; Enforced overexpression of BDNF effectively reversed the tumor suppressive functions of miR-107 on NSCLC proliferation migration and invasion; miR-107 overexpression or downregulation of BDNF was able to inhibit activation of PI3K/AKT signaling pathway; Taken together our findings present the first evidence that miR-107 could suppress NSCLC metastasis by targeting BDNF and indirectly regulating PI3K/AKT signaling pathway which might lead to a potential therapeutic strategy focusing on miR-107 and BDNF for human NSCLC
50 hsa-miR-148a-5p BDNF -0.77 0 0.05 0.83189 mirMAP -0.26 0.00044 NA
51 hsa-miR-192-3p BDNF -0.64 0.00027 0.05 0.83189 MirTarget; miRNATAP -0.32 0 NA
52 hsa-miR-30d-5p BDNF 0.72 0 0.05 0.83189 miRNATAP -0.3 0.00095 NA
53 hsa-miR-589-5p BDNF 1.19 0 0.05 0.83189 miRNATAP -0.24 0.00999 NA
54 hsa-miR-199a-5p BRCA1 -1.99 0 0.89 0 miRanda -0.14 0 NA
55 hsa-miR-29b-1-5p BRCA1 -0.54 0.00103 0.89 0 mirMAP -0.18 0.00026 NA
56 hsa-miR-106a-5p CCND1 -0.46 0.00972 -0.9 1.0E-5 MirTarget; miRNATAP -0.26 0 NA
57 hsa-miR-106b-5p CCND1 0.65 0 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.43 0 NA
58 hsa-miR-1266-5p CCND1 1.63 0 -0.9 1.0E-5 MirTarget -0.23 0 NA
59 hsa-miR-15b-5p CCND1 0.23 0.08248 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.54 0 NA
60 hsa-miR-16-5p CCND1 -0.4 0.0001 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.31 0.00178 23991964; 22922827; 18483394 At the molecular level our results further revealed that cyclin D1 expression was negatively regulated by miR-16;CCND1 has been found to be a target of miR-15a and miR-16-1 through analysis of complementary sequences between microRNAs and CCND1 mRNA; Moreover the transcription of CCND1 is suppressed by miR-15a and miR-16-1 via direct binding to the CCND1 3'-untranslated region 3'-UTR;Truncation in CCND1 mRNA alters miR 16 1 regulation in mantle cell lymphoma; Furthermore we demonstrated that this truncation alters miR-16-1 binding sites and through the use of reporter constructs we were able to show that miR-16-1 regulates CCND1 mRNA expression; This study introduces the role of miR-16-1 in the regulation of CCND1 in MCL
61 hsa-miR-17-5p CCND1 0.7 2.0E-5 -0.9 1.0E-5 miRNAWalker2 validate; MirTarget; TargetScan; miRNATAP -0.34 0 26431674 Bioinformatics Prediction and In Vitro Analysis Revealed That miR 17 Targets Cyclin D1 mRNA in Triple Negative Breast Cancer Cells; In this study using bioinformatic analyses miR-17 was selected as it targets the 3'UTR of CCND1 gene with the highest score; After lentiviral transduction of miR-17 to the target cells gene expression analysis showed decreased expression of CCND1 gene
62 hsa-miR-186-5p CCND1 -0.06 0.53529 -0.9 1.0E-5 mirMAP -0.32 0.00286 NA
63 hsa-miR-19a-3p CCND1 1.02 0 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; miRNATAP -0.28 0 25985117 Moreover miR-19a might play inhibitory roles in HCC malignancy via regulating Cyclin D1 expression
64 hsa-miR-19b-1-5p CCND1 -0.28 0.07831 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase -0.31 0 NA
65 hsa-miR-19b-3p CCND1 0.6 0.00017 -0.9 1.0E-5 miRNATAP -0.34 0 NA
66 hsa-miR-20a-5p CCND1 0.85 0 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.33 0 NA
67 hsa-miR-20b-5p CCND1 0.46 0.02859 -0.9 1.0E-5 MirTarget; miRNATAP -0.23 0 NA
68 hsa-miR-340-5p CCND1 -0 0.9685 -0.9 1.0E-5 mirMAP -0.32 0.00013 NA
69 hsa-miR-425-5p CCND1 0.59 2.0E-5 -0.9 1.0E-5 miRNAWalker2 validate -0.39 0 NA
70 hsa-miR-503-5p CCND1 0.19 0.26842 -0.9 1.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget -0.16 0.00815 26047605; 23731275 MiR 503 inhibited cell proliferation of human breast cancer cells by suppressing CCND1 expression; Overexpression of miR-503 in breast cancer cell lines reduced cell proliferation through inducing G0/G1 cell cycle arrest by targeting CCND1;MicroRNA 503 suppresses proliferation and cell cycle progression of endometrioid endometrial cancer by negatively regulating cyclin D1; CCND1 has a binding sequence of miR-503 within its 3' untranslated region and was confirmed to be a direct target of miR-503 by the fluorescent reporter assays; Increasing the miR-503 level in EEC cells suppressed cell viability colon formation activity and cell-cycle progression and the inhibited oncogenic phenotypes induced by miR-503 were alleviated by ectopic expression of CCND1 without the untranslated region sequence; Collectively this study suggested that miR-503 plays a tumor-suppressor role by targeting CCND1; Abnormal suppression of miR-503 leads to an increase in the CCND1 level which may promote carcinogenesis and progression of EEC
71 hsa-miR-589-3p CCND1 1.17 0 -0.9 1.0E-5 MirTarget -0.18 0.00124 NA
72 hsa-miR-616-5p CCND1 0.15 0.40284 -0.9 1.0E-5 mirMAP -0.26 1.0E-5 NA
73 hsa-miR-7-1-3p CCND1 -0.57 2.0E-5 -0.9 1.0E-5 mirMAP -0.26 0.00057 NA
74 hsa-miR-9-5p CCND1 1.26 9.0E-5 -0.9 1.0E-5 miRNAWalker2 validate -0.14 1.0E-5 NA
75 hsa-miR-92a-3p CCND1 0.21 0.13429 -0.9 1.0E-5 miRNAWalker2 validate -0.41 0 NA
76 hsa-miR-93-5p CCND1 1.4 0 -0.9 1.0E-5 miRNAWalker2 validate; MirTarget; miRNATAP -0.34 0 NA
77 hsa-miR-942-5p CCND1 0.35 0.02833 -0.9 1.0E-5 MirTarget -0.25 0.00012 NA
78 hsa-miR-130b-5p CCND2 0.17 0.33761 0.36 0.03656 mirMAP -0.17 0.00018 NA
79 hsa-miR-20a-5p CCND2 0.85 0 0.36 0.03656 miRNAWalker2 validate; miRTarBase; miRNATAP -0.16 0.00121 NA
80 hsa-miR-28-5p CCND2 -0.43 0 0.36 0.03656 miRanda -0.48 0 NA
81 hsa-miR-33a-3p CCND2 -0.68 1.0E-5 0.36 0.03656 MirTarget -0.26 0 NA
82 hsa-miR-3607-3p CCND2 -2.16 0 0.36 0.03656 mirMAP -0.12 0.0007 NA
83 hsa-miR-378a-3p CCND2 -1.19 0 0.36 0.03656 miRNAWalker2 validate -0.18 2.0E-5 NA
84 hsa-miR-548v CCND2 -0.27 0.17626 0.36 0.03656 MirTarget -0.15 0.00034 NA
85 hsa-miR-616-5p CCND2 0.15 0.40284 0.36 0.03656 mirMAP -0.32 0 NA
86 hsa-miR-618 CCND2 0.14 0.51715 0.36 0.03656 mirMAP -0.23 0 NA
87 hsa-miR-27b-3p CCND3 -0.82 0 0.08 0.47843 miRNAWalker2 validate -0.24 0 NA
88 hsa-miR-320a CCND3 0.33 0.02214 0.08 0.47843 miRanda -0.12 0.00135 NA
89 hsa-miR-125b-5p CCNE1 -1.36 0 3.05 0 miRNAWalker2 validate -0.8 0 NA
90 hsa-miR-192-5p CCNE1 -0.5 0.00345 3.05 0 miRNAWalker2 validate -0.35 2.0E-5 NA
91 hsa-miR-195-5p CCNE1 -1.86 0 3.05 0 miRNAWalker2 validate; MirTarget; miRNATAP -0.3 4.0E-5 24402230 Furthermore through qPCR and western blot assays we showed that overexpression of miR-195-5p reduced CCNE1 mRNA and protein levels respectively
92 hsa-miR-26a-5p CCNE1 -0.96 0 3.05 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.6 2.0E-5 22094936 Cell cycle regulation and CCNE1 and CDC2 were the only significant overlapping pathway and genes differentially expressed between tumors with high and low levels of miR-26a and EZH2 respectively; Low mRNA levels of EZH2 CCNE1 and CDC2 and high levels of miR-26a are associated with favorable outcome on tamoxifen
93 hsa-miR-26b-5p CCNE1 -1.11 0 3.05 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.89 0 NA
94 hsa-miR-424-5p CCNE1 -2.63 0 3.05 0 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.37 0 NA
95 hsa-miR-497-5p CCNE1 -1.41 0 3.05 0 MirTarget; miRNATAP -0.27 0.00125 24112607; 25909221; 24909281 Western blot assays confirmed that overexpression of miR-497 reduced cyclin E1 protein levels; Inhibited cellular growth suppressed cellular migration and invasion and G1 cell cycle arrest were observed upon overexpression of miR-497 in cells possibly by targeting cyclin E1;The effect of simultaneous overexpression of miR-497 and miR-34a on the inhibition of cell proliferation colony formation and tumor growth and the downregulation of cyclin E1 was stronger than the effect of each miRNA alone; The synergistic actions of miR-497 and miR-34a partly correlated with cyclin E1 levels; These results indicate cyclin E1 is downregulated by both miR-497 and miR-34a which synergistically retard the growth of human lung cancer cells;miR 497 suppresses proliferation of human cervical carcinoma HeLa cells by targeting cyclin E1; Furthermore the target effect of miR-497 on the CCNE1 was identified by dual-luciferase reporter assay system qRT-PCR and Western blotting; Over-expressed miR-497 in HeLa cells could suppress cell proliferation by targeting CCNE1
96 hsa-let-7b-3p CCNE2 -1.22 0 2.02 0 mirMAP -0.27 0.00021 NA
97 hsa-miR-126-3p CCNE2 -0.65 0 2.02 0 miRNAWalker2 validate -0.39 5.0E-5 NA
98 hsa-miR-26a-5p CCNE2 -0.96 0 2.02 0 miRNAWalker2 validate; miRTarBase; miRNATAP -0.49 0 24116110; 21901171 The loss of miR 26a mediated post transcriptional regulation of cyclin E2 in pancreatic cancer cell proliferation and decreased patient survival; The in vitro and in vivo assays showed that overexpression of miR-26a resulted in cell cycle arrest inhibited cell proliferation and decreased tumor growth which was associated with cyclin E2 downregulation;We also show that enforced expression of miR-26a in AML cells is able to inhibit cell cycle progression by downregulating cyclin E2 expression
99 hsa-miR-26b-5p CCNE2 -1.11 0 2.02 0 miRNATAP -0.58 0 NA
100 hsa-miR-30a-5p CCNE2 -0.63 0.00011 2.02 0 miRNATAP -0.36 0 NA
101 hsa-miR-122-5p CDK4 -1.24 0 0.67 0 miRNAWalker2 validate -0.12 0 NA
102 hsa-miR-145-5p CDK4 -1.48 0 0.67 0 miRNAWalker2 validate; miRTarBase -0.15 0 21092188 Furthermore we found that CDK4 was regulated by miR-145 in cell cycle control
103 hsa-miR-193b-3p CDK4 -0.17 0.27202 0.67 0 miRNAWalker2 validate -0.15 0 NA
104 hsa-miR-195-5p CDK4 -1.86 0 0.67 0 miRNAWalker2 validate; miRTarBase -0.18 0 NA
105 hsa-let-7a-3p CDK6 -0.57 0 -0.31 0.22057 miRNATAP -0.34 0.00261 NA
106 hsa-let-7b-5p CDK6 -0.96 0 -0.31 0.22057 miRNAWalker2 validate; miRTarBase -0.22 0.00756 NA
107 hsa-miR-106a-5p CDK6 -0.46 0.00972 -0.31 0.22057 mirMAP -0.28 4.0E-5 NA
108 hsa-miR-106b-5p CDK6 0.65 0 -0.31 0.22057 mirMAP -0.39 0.00029 NA
109 hsa-miR-141-3p CDK6 -0.35 0.257 -0.31 0.22057 TargetScan; miRNATAP -0.14 0.00031 NA
110 hsa-miR-148b-3p CDK6 0.27 0.00185 -0.31 0.22057 mirMAP -0.76 0 NA
111 hsa-miR-16-5p CDK6 -0.4 0.0001 -0.31 0.22057 miRNAWalker2 validate; miRTarBase -0.5 3.0E-5 NA
112 hsa-miR-17-5p CDK6 0.7 2.0E-5 -0.31 0.22057 TargetScan; mirMAP -0.33 0 NA
113 hsa-miR-182-5p CDK6 1.97 0 -0.31 0.22057 mirMAP -0.11 0.00279 NA
114 hsa-miR-195-5p CDK6 -1.86 0 -0.31 0.22057 miRNAWalker2 validate; miRTarBase -0.26 2.0E-5 23333942 Expression of cyclin-dependent kinase 6 and vascular endothelial growth factor was down-regulated by exogenous miR-195 and miR-378 respectively
115 hsa-miR-200c-3p CDK6 -0.1 0.71696 -0.31 0.22057 mirMAP -0.12 0.00446 NA
116 hsa-miR-20a-5p CDK6 0.85 0 -0.31 0.22057 mirMAP -0.34 0 NA
117 hsa-miR-20b-5p CDK6 0.46 0.02859 -0.31 0.22057 mirMAP -0.21 0.0003 26166554 The transfection of miR-20b into EJ cells induced G1 phase cell cycle arrest via the decreased expression of cyclin D1 CDK2 and CDK6 without affecting another G1 phase cell cycle regulator cyclin E
118 hsa-miR-217 CDK6 1.06 0.0401 -0.31 0.22057 mirMAP -0.18 0 NA
119 hsa-miR-224-3p CDK6 1.41 0 -0.31 0.22057 mirMAP -0.14 0.00324 NA
120 hsa-miR-26a-5p CDK6 -0.96 0 -0.31 0.22057 miRNAWalker2 validate; miRTarBase; miRNATAP -0.45 0.00013 26314438 Maxvision immunohistochemistry technique was used to detect the expression level of CDK6 and miR-26a in tissue of 20 ENKTCL cases 10 cases of proliferative lymphadenitis and 10 samples of normal lymph node respectively; The possible role of miR-26a and its target gene CDK6 in genesis and development of ENKTCL were analyzed according to the clinical features of ENKTCL patients; Correlation analysis showed that there was significant negative correlation between miR-26a expression and CDK6 expression r = -0.54 P = 0.04
121 hsa-miR-338-3p CDK6 0.54 0.00461 -0.31 0.22057 mirMAP -0.19 0.00245 NA
122 hsa-miR-340-5p CDK6 -0 0.9685 -0.31 0.22057 mirMAP -0.59 0 NA
123 hsa-miR-425-5p CDK6 0.59 2.0E-5 -0.31 0.22057 mirMAP -0.37 2.0E-5 NA
124 hsa-miR-452-5p CDK6 1.92 0 -0.31 0.22057 mirMAP -0.15 0.00162 NA
125 hsa-miR-497-5p CDK6 -1.41 0 -0.31 0.22057 miRNATAP -0.34 0 NA
126 hsa-miR-502-3p CDK6 0.66 0 -0.31 0.22057 PITA; miRNATAP -0.49 0 NA
127 hsa-miR-616-5p CDK6 0.15 0.40284 -0.31 0.22057 mirMAP -0.22 0.00134 NA
128 hsa-miR-885-5p CDK6 -0.94 0.00119 -0.31 0.22057 mirMAP -0.31 0 NA
129 hsa-miR-92a-3p CDK6 0.21 0.13429 -0.31 0.22057 miRNATAP -0.48 0 NA
130 hsa-miR-106b-5p CDKN1A 0.65 0 -0.77 6.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.44 0 NA
131 hsa-miR-146b-5p CDKN1A 0.42 0.04574 -0.77 6.0E-5 miRNAWalker2 validate -0.15 0.00059 27602131 During the search for potential targets of miR-146b in ATC p21 also known as p21Waf1/Cip1 or CDKN1A was noted for its role in cell cycle progression and tumor pathogenesis
132 hsa-miR-17-5p CDKN1A 0.7 2.0E-5 -0.77 6.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; TargetScan; miRNATAP -0.3 0 26482648; 24989082 The low expressions of miR-17 and miR-92 families can maintain cisplatin resistance through the regulation of CDKN1A and RAD21;According to PicTar and Miranda algorithms which predicted CDKN1A p21 as a putative target of miR-17 a luciferase assay was performed and revealed that miR-17 directly targets the 3'-UTR of p21 mRNA
133 hsa-miR-20a-5p CDKN1A 0.85 0 -0.77 6.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.28 0 26012475 Using the poorly tumorigenic and TGF-β-sensitive FET cell line that expresses low miR-20a levels we first confirmed that miR-20a downmodulated CDKN1A expression both at mRNA and protein level through direct binding to its 3'-UTR; Moreover besides modulating CDKN1A miR-20a blocked TGF-β-induced transactivation of its promoter without affecting the post-receptor activation of Smad3/4 effectors directly; Finally miR-20a abrogated the TGF-β-mediated c-Myc repression a direct inhibitor of the CDKN1A promoter activation most likely by reducing the expression of specific MYC-regulating genes from the Smad/E2F-based core repressor complex
134 hsa-miR-423-3p CDKN1A 0.3 0.00067 -0.77 6.0E-5 miRNAWalker2 validate; miRTarBase -0.42 6.0E-5 NA
135 hsa-miR-423-5p CDKN1A 0.7 0 -0.77 6.0E-5 MirTarget -0.37 3.0E-5 NA
136 hsa-miR-503-5p CDKN1A 0.19 0.26842 -0.77 6.0E-5 miRNAWalker2 validate; miRTarBase -0.14 0.00973 NA
137 hsa-miR-93-5p CDKN1A 1.4 0 -0.77 6.0E-5 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.45 0 25633810 MicroRNA 93 activates c Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A; We confirmed that miR-93 directly bound with the 3' untranslated regions of the tumor-suppressor genes PTEN and CDKN1A respectivelyand inhibited their expression; We concluded that miR-93 stimulated cell proliferation migration and invasion through the oncogenic c-Met/PI3K/Akt pathway and also inhibited apoptosis by directly inhibiting PTEN and CDKN1A expression in human HCC
138 hsa-miR-942-5p CDKN1A 0.35 0.02833 -0.77 6.0E-5 miRNAWalker2 validate -0.26 1.0E-5 NA
139 hsa-miR-181a-5p CDKN1B 0.25 0.05519 -0.23 0.00482 miRNAWalker2 validate; miRTarBase -0.13 1.0E-5 NA
140 hsa-miR-221-3p CDKN1B 1.12 0 -0.23 0.00482 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.15 0 20146005; 23637992; 19953484; 23939688; 19126397; 23967190; 17569667; 22992757; 17721077; 20461750 Matched HCC and adjacent non-cancerous samples were assayed for the expression of miR-221 and three G1/S transition inhibitors: p27Kip1 p21WAF1/Cip1and TGF-β1 by in situ hybridization and immunohistochemistry respectively; Real time qRT-PCR was used to investigate miR-221 and p27Kip1 transcripts in different clinical stages; In result miR-221 and TGF-β1 are frequently up-regulated in HCC while p27Kip1 and p21WAF1/Cip1 proteins are frequently down-regulated; In conclusion miR-221 is important in tumorigenesis of HCC possibly by specifically down-regulating p27Kip1 a cell-cycle inhibitor;miR-221 knockdown not only blocked cell cycle progression induced cell apoptosis and inhibited cell proliferation in-vitro but it also inhibited in-vivo tumor growth by targeting p27kip1;Based on bioinformatic analysis we found that the seed sequences of miR-221 and miR-222 coincide with each other and p27kip1 is a target for miRNA-221/222;A Slug/miR-221 network has been suggested linking miR-221 activity with the downregulation of a Slug repressor leading to Slug/miR-221 upregulation and p27Kip1 downregulation; Interference with this process can be achieved using antisense miRNA antagomiR molecules targeting miR-221 inducing the downregulation of Slug and the upregulation of p27Kip1;Moreover a series of functional assays demonstrated that mir-221 could directly inhibit cKit p27Kip1 and possibly other pivotal proteins in melanoma;Additionally the PDGF-dependent increase in cell proliferation appears to be mediated by inhibition of a specific target of miR-221 and down-regulation of p27Kip1;miR 221 and miR 222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1; In all cell lines tested we show an inverse relationship between the expression of miR-221 and miR-222 and the cell cycle inhibitor p27Kip1; Consistently miR-221 and miR-222 knock-down through antisense LNA oligonucleotides increases p27Kip1 in PC3 cells and strongly reduces their clonogenicity in vitro;Peptide nucleic acids targeting miR 221 modulate p27Kip1 expression in breast cancer MDA MB 231 cells; Targeting miR-221 by PNA resulted in i lowering of the hybridization levels of miR-221 measured by RT-qPCR ii upregulation of p27Kip1 gene expression measured by RT-qPCR and western blot analysis;Antagonism of either microRNA 221 or 222 in glioblastoma cells also caused an increase in p27Kip1 levels and enhanced expression of the luciferase reporter gene fused to the p27Kip1 3'UTR;MiR 221 and MiR 222 alterations in sporadic ovarian carcinoma: Relationship to CDKN1B CDKNIC and overall survival; miR-221 and miR-222 negatively regulate expression of CDKN1B p27 and CDKN1C p57 two cell cycle regulators expressed in ovarian surface epithelium and down-regulated in ovarian carcinomas; In contrast CDKN1B expression was not associated with miR-221 or miR-222 expression
141 hsa-miR-222-3p CDKN1B 1.09 0 -0.23 0.00482 miRNAWalker2 validate; miRTarBase; MirTarget; miRNATAP -0.14 0 19953484; 26912358; 24895988; 24137356; 17569667; 27282281; 20461750 Based on bioinformatic analysis we found that the seed sequences of miR-221 and miR-222 coincide with each other and p27kip1 is a target for miRNA-221/222;Besides microvesicle marker characterization we evidenced that miR-222 exosomal expression mostly reflected its abundance in the cells of origin correctly paralleled by repression of its target genes such as p27Kip1 and induction of the PI3K/AKT pathway thus confirming its functional implication in cancer;MiR-222 plays an important role in the tumorigenesis of CC possibly by specifically down-regulating p27Kip1 and PTEN;miR 222 is upregulated in epithelial ovarian cancer and promotes cell proliferation by downregulating P27kip1; miR-222 upregulation induced an enhancement of ovarian cancer cell proliferation potential possibly by downregulating its target P27Kip1; A bioinformatic analysis showed that the 3'-UTR of the P27Kip1 mRNA contained a highly-conserved putative miR-222 binding site; Luciferase reporter assays demonstrated that P27Kip1 was a direct target of miR-222; Consistently there was an inverse correlation between the P27Kip1 and miR-222 expression levels in the ovarian cancer cell lines and tissues;miR 221 and miR 222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1; In all cell lines tested we show an inverse relationship between the expression of miR-221 and miR-222 and the cell cycle inhibitor p27Kip1; Consistently miR-221 and miR-222 knock-down through antisense LNA oligonucleotides increases p27Kip1 in PC3 cells and strongly reduces their clonogenicity in vitro;miR 222 confers the resistance of breast cancer cells to Adriamycin through suppression of p27kip1 expression; Immunofluorescence showed that miR-222 altered the subcellular location of p27kip1 in nucleus; The results showed that downregulation of miR-222 in MCF-7/Adr increased sensitivity to Adr and Adr-induced apoptosis and arrested the cells in G1 phase accompanied by more expressions of p27kip1 especially in nucleus; Taken together the results found that miR-222 induced Adr-resistance at least in part via suppressing p27kip1 expression and altering its subcellular localization and miR-222 inhibitors could reverse Adr-resistance of breast cancer cells;MiR 221 and MiR 222 alterations in sporadic ovarian carcinoma: Relationship to CDKN1B CDKNIC and overall survival; miR-221 and miR-222 negatively regulate expression of CDKN1B p27 and CDKN1C p57 two cell cycle regulators expressed in ovarian surface epithelium and down-regulated in ovarian carcinomas; In contrast CDKN1B expression was not associated with miR-221 or miR-222 expression
142 hsa-miR-24-3p CDKN1B -0.26 0.0069 -0.23 0.00482 miRNAWalker2 validate; miRNATAP -0.13 0.00294 26847530; 26044523 The biological significance of miR-24 expression in prostate cancer cells was assessed by a series of in vitro bioassays and the effect on proposed targets p27 CDKN1B and p16 CDK2NA was investigated;With the bioinformatic method we further identified that p27Kip1 is a direct target of miR-24-3p and its protein level was negatively regulated by miR-24-3p
143 hsa-miR-98-5p CDKN1B -0.05 0.71591 -0.23 0.00482 miRNAWalker2 validate -0.15 0 NA
144 hsa-miR-199a-3p CHAD -2.33 0 -0.97 0.00033 MirTarget; miRNATAP -0.17 0.0002 NA
145 hsa-miR-199b-3p CHAD -2.33 0 -0.97 0.00033 MirTarget -0.17 0.0002 NA
146 hsa-miR-222-5p CHAD 0.13 0.48742 -0.97 0.00033 MirTarget -0.26 0.00034 NA
147 hsa-miR-330-3p CHAD -0.33 0.03161 -0.97 0.00033 miRNATAP -0.45 0 NA
148 hsa-miR-369-3p CHAD -0.68 0.01551 -0.97 0.00033 MirTarget -0.14 0.00327 NA
149 hsa-miR-493-3p CHAD -0.79 0.00723 -0.97 0.00033 MirTarget -0.12 0.00678 NA
150 hsa-miR-15a-5p CHUK 0.35 0.00077 -0.2 0.00863 miRNAWalker2 validate; miRTarBase; MirTarget -0.12 0.00057 NA
NumGOOverlapSizeP ValueAdj. P Value
1 REGULATION OF PHOSPHORUS METABOLIC PROCESS 116 1618 6.094e-67 2.836e-63
2 REGULATION OF PROTEIN MODIFICATION PROCESS 112 1710 5.583e-60 1.299e-56
3 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 68 498 6.018e-55 9.334e-52
4 REGULATION OF KINASE ACTIVITY 79 776 1.972e-54 2.294e-51
5 POSITIVE REGULATION OF RESPONSE TO STIMULUS 111 1929 1.64e-53 1.526e-50
6 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 85 1036 2.873e-51 1.91e-48
7 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 85 1036 2.873e-51 1.91e-48
8 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 72 689 4.984e-50 2.899e-47
9 REGULATION OF TRANSFERASE ACTIVITY 80 946 6.132e-49 3.17e-46
10 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 95 1492 2.914e-48 1.356e-45
11 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 84 1135 4.928e-47 2.084e-44
12 LOCOMOTION 83 1114 1.23e-46 4.771e-44
13 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 97 1656 3.285e-46 1.125e-43
14 REGULATION OF CELL PROLIFERATION 93 1496 3.385e-46 1.125e-43
15 POSITIVE REGULATION OF KINASE ACTIVITY 60 482 9.457e-46 2.934e-43
16 REGULATION OF CELLULAR COMPONENT MOVEMENT 71 771 1.71e-45 4.973e-43
17 POSITIVE REGULATION OF CELL COMMUNICATION 93 1532 2.579e-45 6.667e-43
18 INTRACELLULAR SIGNAL TRANSDUCTION 94 1572 2.575e-45 6.667e-43
19 POSITIVE REGULATION OF CELL PROLIFERATION 72 814 5.678e-45 1.391e-42
20 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 99 1848 7.614e-44 1.771e-41
21 POSITIVE REGULATION OF MOLECULAR FUNCTION 97 1791 3.259e-43 7.22e-41
22 POSITIVE REGULATION OF LOCOMOTION 55 420 5.142e-43 1.088e-40
23 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 72 876 8.752e-43 1.771e-40
24 PROTEIN PHOSPHORYLATION 74 944 1.24e-42 2.403e-40
25 POSITIVE REGULATION OF CATALYTIC ACTIVITY 88 1518 6.266e-41 1.166e-38
26 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 61 616 1.409e-40 2.521e-38
27 REGULATION OF CELL DEATH 86 1472 3.905e-40 6.73e-38
28 EXTRACELLULAR STRUCTURE ORGANIZATION 47 304 4.521e-40 7.512e-38
29 CELL MOTILITY 68 835 5.601e-40 8.687e-38
30 LOCALIZATION OF CELL 68 835 5.601e-40 8.687e-38
31 REGULATION OF MAPK CASCADE 62 660 6.632e-40 9.955e-38
32 RESPONSE TO ENDOGENOUS STIMULUS 85 1450 1.018e-39 1.481e-37
33 POSITIVE REGULATION OF MAPK CASCADE 54 470 3.744e-39 5.279e-37
34 PHOSPHORYLATION 78 1228 1.546e-38 2.116e-36
35 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 79 1275 2.617e-38 3.48e-36
36 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 35 138 7.271e-38 9.398e-36
37 RESPONSE TO EXTERNAL STIMULUS 91 1821 2.775e-37 3.49e-35
38 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 52 470 7.957e-37 9.744e-35
39 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 87 1672 9.576e-37 1.142e-34
40 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 43 289 6.724e-36 7.821e-34
41 NEGATIVE REGULATION OF CELL DEATH 65 872 9.169e-36 1.041e-33
42 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 68 1008 8.323e-35 9.221e-33
43 RESPONSE TO OXYGEN CONTAINING COMPOUND 77 1381 4.574e-34 4.949e-32
44 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 90 1977 1.247e-33 1.319e-31
45 RESPONSE TO HORMONE 63 893 3.302e-33 3.415e-31
46 TISSUE DEVELOPMENT 79 1518 5.891e-33 5.959e-31
47 RESPONSE TO GROWTH FACTOR 48 475 4.224e-32 4.182e-30
48 REGULATION OF MAP KINASE ACTIVITY 41 319 1.351e-31 1.309e-29
49 POSITIVE REGULATION OF MAP KINASE ACTIVITY 35 207 2.986e-31 2.835e-29
50 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 73 1395 2.357e-30 2.19e-28
51 INOSITOL LIPID MEDIATED SIGNALING 29 124 2.401e-30 2.19e-28
52 PEPTIDYL TYROSINE MODIFICATION 33 186 3.269e-30 2.925e-28
53 BIOLOGICAL ADHESION 63 1032 1.29e-29 1.133e-27
54 REGULATION OF HYDROLASE ACTIVITY 70 1327 3.282e-29 2.828e-27
55 RESPONSE TO NITROGEN COMPOUND 57 859 1.615e-28 1.366e-26
56 TAXIS 44 464 3.097e-28 2.574e-26
57 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 64 1142 5.292e-28 4.32e-26
58 REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 32 213 6.255e-27 5.018e-25
59 CELL SUBSTRATE ADHESION 29 164 1.377e-26 1.086e-24
60 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 59 1021 2.159e-26 1.674e-24
61 CARDIOVASCULAR SYSTEM DEVELOPMENT 52 788 7.91e-26 5.937e-24
62 CIRCULATORY SYSTEM DEVELOPMENT 52 788 7.91e-26 5.937e-24
63 REGULATION OF CELL ADHESION 47 629 1.297e-25 9.58e-24
64 RESPONSE TO PEPTIDE 39 404 2.508e-25 1.795e-23
65 SIGNAL TRANSDUCTION BY PROTEIN PHOSPHORYLATION 39 404 2.508e-25 1.795e-23
66 VASCULATURE DEVELOPMENT 41 469 6.115e-25 4.311e-23
67 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 51 799 1.169e-24 8.116e-23
68 ORGAN MORPHOGENESIS 52 841 1.64e-24 1.122e-22
69 ACTIVATION OF PROTEIN KINASE ACTIVITY 33 279 2.532e-24 1.708e-22
70 CELL DEATH 56 1001 2.636e-24 1.752e-22
71 CELL DEVELOPMENT 66 1426 3.341e-24 2.19e-22
72 CELLULAR RESPONSE TO NITROGEN COMPOUND 41 505 1.042e-23 6.736e-22
73 ANGIOGENESIS 33 293 1.232e-23 7.855e-22
74 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 54 957 1.382e-23 8.691e-22
75 REGULATION OF LIPID KINASE ACTIVITY 18 48 1.927e-23 1.195e-21
76 CELLULAR RESPONSE TO HORMONE STIMULUS 42 552 3.453e-23 2.114e-21
77 LEUKOCYTE MIGRATION 31 259 4.785e-23 2.892e-21
78 PEPTIDYL AMINO ACID MODIFICATION 50 841 8.504e-23 5.054e-21
79 POSITIVE REGULATION OF PEPTIDYL TYROSINE PHOSPHORYLATION 26 162 8.58e-23 5.054e-21
80 BLOOD VESSEL MORPHOGENESIS 35 364 1.027e-22 5.927e-21
81 LIPID PHOSPHORYLATION 22 99 1.032e-22 5.927e-21
82 REGULATION OF CELL DIFFERENTIATION 65 1492 2.207e-22 1.252e-20
83 CELL MATRIX ADHESION 23 119 3.292e-22 1.824e-20
84 RESPONSE TO ABIOTIC STIMULUS 54 1024 3.293e-22 1.824e-20
85 REGULATION OF CELL CYCLE 52 949 4.096e-22 2.242e-20
86 POSITIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 25 154 4.429e-22 2.396e-20
87 REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 16 40 1.644e-21 8.792e-20
88 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 56 1152 2.292e-21 1.212e-19
89 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 70 1805 2.432e-21 1.272e-19
90 POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 18 62 4.25e-21 2.197e-19
91 POSITIVE REGULATION OF GENE EXPRESSION 68 1733 5.84e-21 2.986e-19
92 RESPONSE TO LIPID 49 888 6.004e-21 3.036e-19
93 REGULATION OF EPITHELIAL CELL PROLIFERATION 30 285 1.07e-20 5.354e-19
94 INTEGRIN MEDIATED SIGNALING PATHWAY 19 82 3.865e-20 1.913e-18
95 RESPONSE TO WOUNDING 39 563 4.197e-20 2.048e-18
96 CELLULAR RESPONSE TO PEPTIDE 29 274 4.224e-20 2.048e-18
97 POSITIVE REGULATION OF HYDROLASE ACTIVITY 48 905 8.329e-20 3.955e-18
98 REGULATION OF VASCULATURE DEVELOPMENT 27 233 8.298e-20 3.955e-18
99 REGULATION OF PHOSPHOLIPID METABOLIC PROCESS 17 61 1.196e-19 5.622e-18
100 PHOSPHATIDYLINOSITOL METABOLIC PROCESS 25 193 1.329e-19 6.183e-18
101 REGULATION OF IMMUNE SYSTEM PROCESS 59 1403 1.817e-19 8.372e-18
102 POSITIVE REGULATION OF CHEMOTAXIS 21 120 2.017e-19 9.202e-18
103 EMBRYO DEVELOPMENT 47 894 3.083e-19 1.393e-17
104 REGULATION OF RESPONSE TO STRESS 60 1468 3.296e-19 1.475e-17
105 REGULATION OF CHEMOTAXIS 24 180 3.693e-19 1.636e-17
106 CELL PROLIFERATION 41 672 4.216e-19 1.851e-17
107 POSITIVE REGULATION OF CELL DEATH 39 605 5.182e-19 2.253e-17
108 REGULATION OF NEURON DEATH 27 252 6.492e-19 2.797e-17
109 NEUROGENESIS 58 1402 8.663e-19 3.698e-17
110 REGULATION OF LIPID METABOLIC PROCESS 28 282 1.083e-18 4.581e-17
111 PROTEIN AUTOPHOSPHORYLATION 24 192 1.719e-18 7.205e-17
112 REGULATION OF ERK1 AND ERK2 CASCADE 26 238 1.844e-18 7.661e-17
113 POSITIVE REGULATION OF ERK1 AND ERK2 CASCADE 23 172 1.965e-18 8.092e-17
114 RESPONSE TO ACID CHEMICAL 29 319 2.83e-18 1.155e-16
115 CELL ACTIVATION 37 568 3.279e-18 1.326e-16
116 POSITIVE REGULATION OF IMMUNE SYSTEM PROCESS 45 867 3.305e-18 1.326e-16
117 WOUND HEALING 34 470 3.572e-18 1.42e-16
118 RESPONSE TO ORGANIC CYCLIC COMPOUND 46 917 4.945e-18 1.95e-16
119 REGULATION OF PROTEIN PHOSPHATASE TYPE 2A ACTIVITY 12 24 6.591e-18 2.577e-16
120 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 35 513 6.922e-18 2.684e-16
121 IMMUNE SYSTEM PROCESS 68 1984 8.291e-18 3.188e-16
122 LIPID MODIFICATION 24 210 1.418e-17 5.41e-16
123 POSITIVE REGULATION OF CELL DIFFERENTIATION 43 823 1.639e-17 6.2e-16
124 REGULATION OF TRANSPORT 64 1804 1.969e-17 7.389e-16
125 POSITIVE REGULATION OF CELL ADHESION 30 376 2.723e-17 1.013e-15
126 REGULATION OF CELL SUBSTRATE ADHESION 22 173 3.351e-17 1.237e-15
127 POSITIVE REGULATION OF TRANSPORT 45 936 6.033e-17 2.21e-15
128 ACTIVATION OF MAPK ACTIVITY 20 137 6.148e-17 2.235e-15
129 CELLULAR COMPONENT MORPHOGENESIS 44 900 7.675e-17 2.768e-15
130 EPITHELIUM DEVELOPMENT 45 945 8.638e-17 3.092e-15
131 REGULATION OF PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 15 60 1.088e-16 3.864e-15
132 SINGLE ORGANISM CELL ADHESION 32 459 1.105e-16 3.894e-15
133 PHOSPHATIDYLINOSITOL 3 PHOSPHATE BIOSYNTHETIC PROCESS 14 49 1.456e-16 5.095e-15
134 REGULATION OF EPITHELIAL CELL MIGRATION 21 166 2.012e-16 6.988e-15
135 REGULATION OF RESPONSE TO EXTERNAL STIMULUS 44 926 2.183e-16 7.525e-15
136 REGULATION OF DEVELOPMENTAL GROWTH 26 289 2.275e-16 7.785e-15
137 POSITIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 26 296 4.076e-16 1.384e-14
138 TUBE DEVELOPMENT 34 552 4.706e-16 1.587e-14
139 GLYCEROLIPID METABOLIC PROCESS 28 356 4.888e-16 1.636e-14
140 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 53 1360 4.969e-16 1.651e-14
141 REGULATION OF ENDOTHELIAL CELL MIGRATION 18 114 5.538e-16 1.827e-14
142 POSITIVE REGULATION OF CELL CYCLE 27 332 7.367e-16 2.414e-14
143 RESPONSE TO STEROID HORMONE 32 497 1.071e-15 3.484e-14
144 RESPONSE TO OXYGEN LEVELS 26 311 1.349e-15 4.36e-14
145 PLATELET ACTIVATION 19 142 1.991e-15 6.388e-14
146 CELL PROJECTION ORGANIZATION 42 902 2.374e-15 7.567e-14
147 REGULATION OF CELL MATRIX ADHESION 16 90 3.439e-15 1.089e-13
148 GLYCEROPHOSPHOLIPID METABOLIC PROCESS 25 297 4.189e-15 1.317e-13
149 REGULATION OF GROWTH 35 633 4.414e-15 1.378e-13
150 UROGENITAL SYSTEM DEVELOPMENT 25 299 4.894e-15 1.518e-13
151 RESPONSE TO ALCOHOL 27 362 6.26e-15 1.929e-13
152 REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 19 152 7.174e-15 2.196e-13
153 POSITIVE REGULATION OF CELL DIVISION 18 132 7.959e-15 2.421e-13
154 POSITIVE REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 12 39 8.23e-15 2.487e-13
155 POSITIVE REGULATION OF VASCULATURE DEVELOPMENT 18 133 9.115e-15 2.736e-13
156 NEGATIVE REGULATION OF CELL CYCLE 29 433 9.559e-15 2.851e-13
157 NEURON PROJECTION DEVELOPMENT 32 545 1.422e-14 4.213e-13
158 RESPONSE TO INSULIN 21 205 1.501e-14 4.42e-13
159 GROWTH 28 410 1.759e-14 5.149e-13
160 APOPTOTIC SIGNALING PATHWAY 24 289 2.065e-14 6.005e-13
161 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 37 750 2.35e-14 6.793e-13
162 PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROCESS 17 120 2.374e-14 6.82e-13
163 POSITIVE REGULATION OF LIPID KINASE ACTIVITY 11 32 2.716e-14 7.754e-13
164 REGULATION OF GTPASE ACTIVITY 35 673 2.739e-14 7.77e-13
165 REGULATION OF NEURON APOPTOTIC PROCESS 20 192 4.734e-14 1.335e-12
166 REGULATION OF APOPTOTIC SIGNALING PATHWAY 26 363 5.329e-14 1.494e-12
167 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 24 303 5.879e-14 1.638e-12
168 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 14 74 7.696e-14 2.132e-12
169 REGULATION OF BODY FLUID LEVELS 30 506 7.95e-14 2.186e-12
170 NEURON PROJECTION MORPHOGENESIS 27 402 7.985e-14 2.186e-12
171 FORMATION OF PRIMARY GERM LAYER 16 110 9.193e-14 2.501e-12
172 RESPONSE TO EXTRACELLULAR STIMULUS 28 441 1.076e-13 2.911e-12
173 RESPONSE TO AMINO ACID 16 112 1.229e-13 3.305e-12
174 REGULATION OF CELL DEVELOPMENT 38 836 1.305e-13 3.49e-12
175 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 18 156 1.546e-13 4.087e-12
176 CELLULAR RESPONSE TO STRESS 53 1565 1.542e-13 4.087e-12
177 REGULATION OF CELL PROJECTION ORGANIZATION 31 558 1.675e-13 4.402e-12
178 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 37 801 1.76e-13 4.6e-12
179 REGULATION OF DEPHOSPHORYLATION 18 158 1.932e-13 5.023e-12
180 NEGATIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 41 983 2.096e-13 5.417e-12
181 SUBSTRATE ADHESION DEPENDENT CELL SPREADING 11 38 2.389e-13 6.142e-12
182 REGULATION OF FIBROBLAST PROLIFERATION 14 81 2.873e-13 7.345e-12
183 TISSUE MORPHOGENESIS 30 533 3.056e-13 7.77e-12
184 REGULATION OF CELLULAR RESPONSE TO STRESS 34 691 3.237e-13 8.186e-12
185 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 25 360 3.365e-13 8.463e-12
186 GLAND DEVELOPMENT 26 395 3.796e-13 9.497e-12
187 EMBRYONIC MORPHOGENESIS 30 539 4.075e-13 1.014e-11
188 REGULATION OF PROTEIN KINASE B SIGNALING 16 121 4.229e-13 1.047e-11
189 PHOSPHOLIPID METABOLIC PROCESS 25 364 4.308e-13 1.061e-11
190 CENTRAL NERVOUS SYSTEM DEVELOPMENT 38 872 4.789e-13 1.173e-11
191 POSITIVE REGULATION OF FIBROBLAST PROLIFERATION 12 53 4.895e-13 1.193e-11
192 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 15 103 5.476e-13 1.327e-11
193 POSITIVE REGULATION OF CELL DEVELOPMENT 28 472 5.674e-13 1.368e-11
194 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 27 437 5.84e-13 1.401e-11
195 CELL SUBSTRATE JUNCTION ASSEMBLY 11 41 6.092e-13 1.454e-11
196 HEAD DEVELOPMENT 34 709 6.683e-13 1.586e-11
197 POSITIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 29 514 7.409e-13 1.75e-11
198 REGULATION OF CELLULAR PROTEIN LOCALIZATION 30 552 7.501e-13 1.763e-11
199 REGULATION OF MEMBRANE PERMEABILITY 13 70 7.855e-13 1.837e-11
200 POSITIVE REGULATION OF PHOSPHOLIPID METABOLIC PROCESS 11 42 8.173e-13 1.902e-11
201 REGULATION OF NEURON DIFFERENTIATION 30 554 8.226e-13 1.904e-11
202 REGULATION OF PHOSPHATASE ACTIVITY 16 128 1.03e-12 2.361e-11
203 POSITIVE REGULATION OF LIPID METABOLIC PROCESS 16 128 1.03e-12 2.361e-11
204 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 17 153 1.395e-12 3.181e-11
205 NEURON DEVELOPMENT 33 687 1.449e-12 3.276e-11
206 REGULATION OF PROTEIN LOCALIZATION 39 950 1.45e-12 3.276e-11
207 GASTRULATION 17 155 1.727e-12 3.881e-11
208 CELLULAR RESPONSE TO EXTERNAL STIMULUS 21 264 2.183e-12 4.884e-11
209 POSITIVE REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 12 60 2.398e-12 5.313e-11
210 NEURON DIFFERENTIATION 37 874 2.395e-12 5.313e-11
211 POSITIVE REGULATION OF GROWTH 20 238 2.717e-12 5.992e-11
212 POSITIVE REGULATION OF DNA METABOLIC PROCESS 18 185 2.954e-12 6.483e-11
213 CELL CHEMOTAXIS 17 162 3.558e-12 7.773e-11
214 REGULATION OF CELLULAR LOCALIZATION 45 1277 4.137e-12 8.996e-11
215 REGULATION OF ORGANELLE ORGANIZATION 43 1178 4.322e-12 9.354e-11
216 CELL CYCLE PROCESS 41 1081 4.467e-12 9.622e-11
217 NEGATIVE REGULATION OF ANOIKIS 8 17 4.698e-12 1.007e-10
218 EXTRINSIC APOPTOTIC SIGNALING PATHWAY 14 99 5.019e-12 1.071e-10
219 RESPONSE TO ESTROGEN 19 218 5.129e-12 1.09e-10
220 REPRODUCTIVE SYSTEM DEVELOPMENT 25 408 5.351e-12 1.127e-10
221 REGULATION OF NEURON PROJECTION DEVELOPMENT 25 408 5.351e-12 1.127e-10
222 REGULATION OF IMMUNE RESPONSE 36 858 6.379e-12 1.337e-10
223 HEMOSTASIS 22 311 6.623e-12 1.382e-10
224 POSITIVE REGULATION OF MITOTIC CELL CYCLE 15 123 7.729e-12 1.605e-10
225 RESPONSE TO ESTRADIOL 16 146 8.033e-12 1.661e-10
226 CELLULAR LIPID METABOLIC PROCESS 37 913 8.619e-12 1.775e-10
227 REGULATION OF CELL SIZE 17 172 9.41e-12 1.929e-10
228 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 12 67 9.595e-12 1.958e-10
229 PEPTIDYL SERINE MODIFICATION 16 148 9.911e-12 2.014e-10
230 POSITIVE REGULATION OF ENDOTHELIAL CELL PROLIFERATION 12 68 1.154e-11 2.334e-10
231 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS 13 86 1.231e-11 2.48e-10
232 CELLULAR RESPONSE TO ACID CHEMICAL 17 175 1.244e-11 2.495e-10
233 POSITIVE REGULATION OF PHOSPHOLIPASE ACTIVITY 11 53 1.307e-11 2.611e-10
234 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 19 232 1.534e-11 3.051e-10
235 RESPONSE TO DRUG 25 431 1.757e-11 3.471e-10
236 REGULATION OF MITOTIC CELL CYCLE 26 468 1.761e-11 3.471e-10
237 CELL CYCLE ARREST 16 154 1.826e-11 3.569e-10
238 FC RECEPTOR SIGNALING PATHWAY 18 206 1.822e-11 3.569e-10
239 NEGATIVE REGULATION OF CELL COMMUNICATION 42 1192 2.473e-11 4.815e-10
240 GLYCEROLIPID BIOSYNTHETIC PROCESS 18 211 2.722e-11 5.277e-10
241 POSITIVE REGULATION OF INTRACELLULAR TRANSPORT 23 370 2.987e-11 5.744e-10
242 MITOCHONDRIAL MEMBRANE ORGANIZATION 13 92 2.978e-11 5.744e-10
243 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 29 602 3.504e-11 6.709e-10
244 POSITIVE REGULATION OF NEURON DIFFERENTIATION 21 306 3.608e-11 6.881e-10
245 REGULATION OF DNA METABOLIC PROCESS 22 340 3.792e-11 7.201e-10
246 CELL CYCLE 44 1316 4.222e-11 7.985e-10
247 REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 11 59 4.527e-11 8.528e-10
248 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 28 573 5.658e-11 1.062e-09
249 SINGLE ORGANISM BEHAVIOR 23 384 6.285e-11 1.17e-09
250 MORPHOGENESIS OF A BRANCHING STRUCTURE 16 167 6.271e-11 1.17e-09
251 MEMORY 13 98 6.759e-11 1.243e-09
252 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY 13 98 6.759e-11 1.243e-09
253 REGULATION OF ENDOTHELIAL CELL PROLIFERATION 13 98 6.759e-11 1.243e-09
254 REGULATION OF AXONOGENESIS 16 168 6.864e-11 1.257e-09
255 REGULATION OF INTRACELLULAR TRANSPORT 29 621 7.34e-11 1.339e-09
256 POSITIVE REGULATION OF CELL SUBSTRATE ADHESION 13 99 7.705e-11 1.4e-09
257 NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS 39 1087 8.454e-11 1.531e-09
258 REGULATION OF SMOOTH MUSCLE CELL PROLIFERATION 13 100 8.77e-11 1.582e-09
259 NEGATIVE REGULATION OF NEURON DEATH 16 171 8.965e-11 1.604e-09
260 POSITIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 16 171 8.965e-11 1.604e-09
261 PROTEIN KINASE B SIGNALING 9 34 9.331e-11 1.664e-09
262 RESPONSE TO CYTOKINE 31 714 9.462e-11 1.68e-09
263 IMMUNE RESPONSE REGULATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 21 323 9.878e-11 1.748e-09
264 REGULATION OF PHOSPHOLIPASE ACTIVITY 11 64 1.145e-10 2.019e-09
265 CELL PART MORPHOGENESIS 29 633 1.154e-10 2.025e-09
266 REGULATION OF CELL MORPHOGENESIS 27 552 1.255e-10 2.196e-09
267 REGULATION OF POSITIVE CHEMOTAXIS 8 24 1.329e-10 2.307e-09
268 REGULATION OF ANOIKIS 8 24 1.329e-10 2.307e-09
269 MORPHOGENESIS OF AN EPITHELIUM 23 400 1.413e-10 2.445e-09
270 NEURON PROJECTION GUIDANCE 17 205 1.54e-10 2.655e-09
271 POSITIVE REGULATION OF LIPASE ACTIVITY 11 66 1.623e-10 2.786e-09
272 POSITIVE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 9 36 1.643e-10 2.8e-09
273 POSITIVE CHEMOTAXIS 9 36 1.643e-10 2.8e-09
274 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 22 368 1.737e-10 2.938e-09
275 DEVELOPMENTAL GROWTH 21 333 1.734e-10 2.938e-09
276 POSITIVE REGULATION OF NEURON DEATH 11 67 1.923e-10 3.229e-09
277 CELL JUNCTION ASSEMBLY 14 129 1.92e-10 3.229e-09
278 PHOSPHATIDYLINOSITOL 3 KINASE SIGNALING 8 25 1.936e-10 3.24e-09
279 POSITIVE REGULATION OF DNA REPLICATION 12 86 2.031e-10 3.388e-09
280 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 21 337 2.16e-10 3.59e-09
281 REGULATION OF CELL DIVISION 19 272 2.387e-10 3.952e-09
282 POSITIVE REGULATION OF LEUKOCYTE MIGRATION 13 109 2.64e-10 4.357e-09
283 POSITIVE REGULATION OF AXONOGENESIS 11 69 2.676e-10 4.384e-09
284 RESPONSE TO ACTIVITY 11 69 2.676e-10 4.384e-09
285 CELL JUNCTION ORGANIZATION 16 185 2.912e-10 4.754e-09
286 REGULATION OF GLUCOSE IMPORT IN RESPONSE TO INSULIN STIMULUS 7 17 3.449e-10 5.592e-09
287 REGULATION OF ENDOTHELIAL CELL CHEMOTAXIS 7 17 3.449e-10 5.592e-09
288 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE 11 71 3.684e-10 5.952e-09
289 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 15 162 4.093e-10 6.59e-09
290 POSITIVE REGULATION OF CELL MATRIX ADHESION 9 40 4.591e-10 7.34e-09
291 ENDODERMAL CELL DIFFERENTIATION 9 40 4.591e-10 7.34e-09
292 MULTICELLULAR ORGANISM METABOLIC PROCESS 12 93 5.168e-10 8.208e-09
293 HEART DEVELOPMENT 24 466 5.162e-10 8.208e-09
294 NEPHRON DEVELOPMENT 13 115 5.202e-10 8.234e-09
295 LIPID METABOLIC PROCESS 39 1158 5.32e-10 8.392e-09
296 FC EPSILON RECEPTOR SIGNALING PATHWAY 14 142 6.946e-10 1.092e-08
297 REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 8 29 7.393e-10 1.154e-08
298 POSITIVE REGULATION OF PROTEIN INSERTION INTO MITOCHONDRIAL MEMBRANE INVOLVED IN APOPTOTIC SIGNALING PATHWAY 8 29 7.393e-10 1.154e-08
299 BEHAVIOR 25 516 7.801e-10 1.214e-08
300 GLUCOSE HOMEOSTASIS 15 170 8.054e-10 1.245e-08
301 CARBOHYDRATE HOMEOSTASIS 15 170 8.054e-10 1.245e-08
302 HOMEOSTATIC PROCESS 42 1337 8.534e-10 1.315e-08
303 REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION INVOLVED IN APOPTOTIC SIGNALING PATHWAY 9 43 9.197e-10 1.408e-08
304 REGULATION OF POLYSACCHARIDE METABOLIC PROCESS 9 43 9.197e-10 1.408e-08
305 POSITIVE REGULATION OF SMOOTH MUSCLE CELL MIGRATION 8 30 9.985e-10 1.518e-08
306 CELLULAR RESPONSE TO VASCULAR ENDOTHELIAL GROWTH FACTOR STIMULUS 8 30 9.985e-10 1.518e-08
307 CELLULAR RESPONSE TO INSULIN STIMULUS 14 146 1.004e-09 1.522e-08
308 REGULATION OF GLUCOSE IMPORT 10 60 1.125e-09 1.699e-08
309 MULTICELLULAR ORGANISMAL MACROMOLECULE METABOLIC PROCESS 11 79 1.203e-09 1.811e-08
310 PHOSPHOLIPID BIOSYNTHETIC PROCESS 17 235 1.279e-09 1.92e-08
311 INSULIN RECEPTOR SIGNALING PATHWAY 11 80 1.381e-09 2.066e-08
312 REGULATION OF RESPONSE TO WOUNDING 22 413 1.52e-09 2.26e-08
313 RESPONSE TO RADIATION 22 413 1.52e-09 2.26e-08
314 POSITIVE REGULATION OF PROTEIN KINASE B SIGNALING 11 81 1.582e-09 2.342e-08
315 SENSORY ORGAN DEVELOPMENT 24 493 1.586e-09 2.342e-08
316 PALLIUM DEVELOPMENT 14 153 1.861e-09 2.741e-08
317 CELLULAR RESPONSE TO LIPID 23 457 1.884e-09 2.766e-08
318 IMMUNE SYSTEM DEVELOPMENT 26 582 1.942e-09 2.841e-08
319 AMEBOIDAL TYPE CELL MIGRATION 14 154 2.028e-09 2.957e-08
320 NEGATIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 25 541 2.052e-09 2.975e-08
321 NEGATIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 25 541 2.052e-09 2.975e-08
322 REGULATION OF LIPASE ACTIVITY 11 83 2.066e-09 2.985e-08
323 RESPONSE TO KETONE 15 182 2.079e-09 2.995e-08
324 REGULATION OF CELLULAR COMPONENT BIOGENESIS 30 767 2.301e-09 3.285e-08
325 SIGNAL TRANSDUCTION IN ABSENCE OF LIGAND 8 33 2.301e-09 3.285e-08
326 EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 8 33 2.301e-09 3.285e-08
327 TISSUE MIGRATION 11 84 2.354e-09 3.35e-08
328 RESPONSE TO GLUCAGON 9 48 2.606e-09 3.697e-08
329 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 23 465 2.623e-09 3.71e-08
330 BRANCHING MORPHOGENESIS OF AN EPITHELIAL TUBE 13 131 2.644e-09 3.728e-08
331 PLATELET DEGRANULATION 12 107 2.682e-09 3.77e-08
332 RESPONSE TO LIGHT STIMULUS 18 280 2.719e-09 3.81e-08
333 POSITIVE REGULATION OF CELL CYCLE PROCESS 17 247 2.73e-09 3.815e-08
334 PLATELET DERIVED GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 8 34 2.981e-09 4.153e-08
335 REGULATION OF SMOOTH MUSCLE CELL MIGRATION 9 49 3.162e-09 4.392e-08
336 CELLULAR RESPONSE TO EXTRACELLULAR STIMULUS 15 188 3.252e-09 4.503e-08
337 COGNITION 17 251 3.482e-09 4.807e-08
338 REGULATION OF DNA REPLICATION 14 161 3.625e-09 4.99e-08
339 REGULATION OF ADHERENS JUNCTION ORGANIZATION 9 50 3.819e-09 5.226e-08
340 ENDODERM FORMATION 9 50 3.819e-09 5.226e-08
341 RESPONSE TO NUTRIENT 15 191 4.041e-09 5.514e-08
342 CELL CYCLE G1 S PHASE TRANSITION 12 111 4.103e-09 5.566e-08
343 G1 S TRANSITION OF MITOTIC CELL CYCLE 12 111 4.103e-09 5.566e-08
344 TUBE MORPHOGENESIS 19 323 4.205e-09 5.688e-08
345 NEGATIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 22 437 4.302e-09 5.801e-08
346 CELL CYCLE PHASE TRANSITION 17 255 4.419e-09 5.926e-08
347 REGULATION OF GENERATION OF PRECURSOR METABOLITES AND ENERGY 11 89 4.408e-09 5.926e-08
348 REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 9 51 4.593e-09 6.141e-08
349 CELL CELL ADHESION 26 608 4.815e-09 6.42e-08
350 VASCULAR ENDOTHELIAL GROWTH FACTOR SIGNALING PATHWAY 6 14 5.007e-09 6.619e-08
351 INSULIN LIKE GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 6 14 5.007e-09 6.619e-08
352 NEGATIVE REGULATION OF CELL DIFFERENTIATION 26 609 4.981e-09 6.619e-08
353 REGULATION OF CELL ACTIVATION 23 484 5.596e-09 7.376e-08
354 POSITIVE REGULATION OF CELLULAR COMPONENT BIOGENESIS 21 406 6.138e-09 8.06e-08
355 RESPIRATORY SYSTEM DEVELOPMENT 15 197 6.167e-09 8.06e-08
356 TELENCEPHALON DEVELOPMENT 16 228 6.154e-09 8.06e-08
357 ENDODERM DEVELOPMENT 10 71 6.189e-09 8.067e-08
358 CELLULAR RESPONSE TO AMINO ACID STIMULUS 9 53 6.562e-09 8.529e-08
359 RESPONSE TO FIBROBLAST GROWTH FACTOR 12 116 6.815e-09 8.833e-08
360 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 34 1004 6.968e-09 9.006e-08
361 CELLULAR RESPONSE TO ABIOTIC STIMULUS 17 263 7.025e-09 9.055e-08
362 RHYTHMIC PROCESS 18 298 7.239e-09 9.305e-08
363 REGULATION OF LEUKOCYTE DIFFERENTIATION 16 232 7.89e-09 1.011e-07
364 POSITIVE REGULATION OF STAT CASCADE 10 73 8.168e-09 1.041e-07
365 POSITIVE REGULATION OF JAK STAT CASCADE 10 73 8.168e-09 1.041e-07
366 EPIDERMAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 9 55 9.235e-09 1.174e-07
367 REGULATION OF PHOSPHOLIPASE C ACTIVITY 8 39 9.628e-09 1.217e-07
368 ERBB2 SIGNALING PATHWAY 8 39 9.628e-09 1.217e-07
369 HOMEOSTASIS OF NUMBER OF CELLS 14 175 1.065e-08 1.343e-07
370 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 12 121 1.104e-08 1.389e-07
371 GLAND MORPHOGENESIS 11 97 1.111e-08 1.393e-07
372 CHEMICAL HOMEOSTASIS 31 874 1.209e-08 1.512e-07
373 MITOCHONDRIAL TRANSPORT 14 177 1.232e-08 1.537e-07
374 REGULATION OF LEUKOCYTE MIGRATION 13 149 1.276e-08 1.587e-07
375 MYELOID LEUKOCYTE MIGRATION 11 99 1.38e-08 1.713e-07
376 RESPONSE TO MECHANICAL STIMULUS 15 210 1.466e-08 1.814e-07
377 ACTIVATION OF IMMUNE RESPONSE 21 427 1.479e-08 1.826e-07
378 INTRINSIC APOPTOTIC SIGNALING PATHWAY 13 152 1.623e-08 1.998e-07
379 REGULATION OF HEMOPOIESIS 18 314 1.63e-08 2.001e-07
380 REGULATION OF CELL GROWTH 20 391 1.729e-08 2.117e-07
381 REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 15 213 1.773e-08 2.166e-07
382 ERBB SIGNALING PATHWAY 10 79 1.787e-08 2.176e-07
383 POSITIVE REGULATION OF IMMUNE RESPONSE 24 563 2.084e-08 2.531e-07
384 FOREBRAIN DEVELOPMENT 19 357 2.126e-08 2.576e-07
385 OSSIFICATION 16 251 2.403e-08 2.905e-07
386 CEREBRAL CORTEX DEVELOPMENT 11 105 2.573e-08 3.102e-07
387 REGULATION OF TYROSINE PHOSPHORYLATION OF STAT3 PROTEIN 8 44 2.644e-08 3.179e-07
388 INTERSPECIES INTERACTION BETWEEN ORGANISMS 26 662 2.721e-08 3.255e-07
389 SYMBIOSIS ENCOMPASSING MUTUALISM THROUGH PARASITISM 26 662 2.721e-08 3.255e-07
390 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 15 220 2.734e-08 3.262e-07
391 SPROUTING ANGIOGENESIS 8 45 3.185e-08 3.79e-07
392 LEUKOCYTE DIFFERENTIATION 17 292 3.3e-08 3.917e-07
393 CELL CELL SIGNALING 28 767 3.609e-08 4.273e-07
394 NEGATIVE REGULATION OF NEURON APOPTOTIC PROCESS 12 135 3.805e-08 4.494e-07
395 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 8 46 3.819e-08 4.498e-07
396 CONNECTIVE TISSUE DEVELOPMENT 14 194 3.948e-08 4.639e-07
397 LIPID BIOSYNTHETIC PROCESS 23 539 4.107e-08 4.813e-07
398 POSITIVE REGULATION OF NEURON APOPTOTIC PROCESS 8 47 4.558e-08 5.329e-07
399 REGULATION OF CARBOHYDRATE BIOSYNTHETIC PROCESS 10 87 4.591e-08 5.354e-07
400 POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 8 48 5.417e-08 6.302e-07
401 REGULATION OF CELL CELL ADHESION 19 380 5.726e-08 6.644e-07
402 NEGATIVE REGULATION OF APOPTOTIC SIGNALING PATHWAY 14 200 5.787e-08 6.699e-07
403 REGULATION OF TYROSINE PHOSPHORYLATION OF STAT PROTEIN 9 68 6.313e-08 7.271e-07
404 REGULATION OF CELL JUNCTION ASSEMBLY 9 68 6.313e-08 7.271e-07
405 GLOMERULUS DEVELOPMENT 8 49 6.413e-08 7.368e-07
406 REGULATION OF CARBOHYDRATE METABOLIC PROCESS 13 172 7.088e-08 8.123e-07
407 POSITIVE REGULATION OF ENDOTHELIAL CELL CHEMOTAXIS 5 11 7.209e-08 8.241e-07
408 REGULATION OF JAK STAT CASCADE 12 144 7.809e-08 8.884e-07
409 REGULATION OF STAT CASCADE 12 144 7.809e-08 8.884e-07
410 LEUKOCYTE CHEMOTAXIS 11 117 7.973e-08 9.026e-07
411 MAMMARY GLAND DEVELOPMENT 11 117 7.973e-08 9.026e-07
412 POSITIVE REGULATION OF CELL ACTIVATION 17 311 8.237e-08 9.303e-07
413 CELLULAR RESPONSE TO CYTOKINE STIMULUS 24 606 8.301e-08 9.352e-07
414 REGULATION OF PROTEIN IMPORT INTO NUCLEUS TRANSLOCATION 6 21 8.476e-08 9.527e-07
415 REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 11 118 8.707e-08 9.739e-07
416 GLIOGENESIS 13 175 8.689e-08 9.739e-07
417 MUSCLE STRUCTURE DEVELOPMENT 20 432 8.914e-08 9.946e-07
418 RESPONSE TO CORTICOSTEROID 13 176 9.29e-08 1.034e-06
419 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 16 278 9.923e-08 1.102e-06
420 REGULATION OF GLYCOGEN METABOLIC PROCESS 7 35 1.006e-07 1.114e-06
421 POSITIVE REGULATION OF CELL CELL ADHESION 15 243 1.016e-07 1.123e-06
422 RESPONSE TO INORGANIC SUBSTANCE 21 479 1.049e-07 1.157e-06
423 REGULATION OF CYTOPLASMIC TRANSPORT 21 481 1.125e-07 1.237e-06
424 SKIN DEVELOPMENT 14 211 1.127e-07 1.237e-06
425 POSITIVE REGULATION OF PROTEIN AUTOPHOSPHORYLATION 6 22 1.155e-07 1.264e-06
426 REGULATION OF NITRIC OXIDE BIOSYNTHETIC PROCESS 8 53 1.213e-07 1.325e-06
427 CELL ADHESION MEDIATED BY INTEGRIN 5 12 1.225e-07 1.331e-06
428 POSITIVE REGULATION OF GLUCOSE IMPORT IN RESPONSE TO INSULIN STIMULUS 5 12 1.225e-07 1.331e-06
429 POSITIVE REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 7 36 1.237e-07 1.341e-06
430 MITOTIC CELL CYCLE 27 766 1.311e-07 1.419e-06
431 NEGATIVE REGULATION OF MOLECULAR FUNCTION 33 1079 1.329e-07 1.434e-06
432 RESPONSE TO VITAMIN 10 98 1.445e-07 1.556e-06
433 REGULATION OF PROTEIN IMPORT 13 183 1.466e-07 1.576e-06
434 POSITIVE REGULATION OF CARBOHYDRATE METABOLIC PROCESS 9 75 1.504e-07 1.612e-06
435 POSITIVE REGULATION OF TYROSINE PHOSPHORYLATION OF STAT3 PROTEIN 7 37 1.511e-07 1.616e-06
436 POSITIVE REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 6 23 1.548e-07 1.652e-06
437 REGULATION OF RAS PROTEIN SIGNAL TRANSDUCTION 13 184 1.562e-07 1.663e-06
438 REGULATION OF GLUCOSE TRANSPORT 10 100 1.751e-07 1.856e-06
439 LIMBIC SYSTEM DEVELOPMENT 10 100 1.751e-07 1.856e-06
440 EPITHELIAL CELL DIFFERENTIATION 21 495 1.814e-07 1.919e-06
441 CELLULAR RESPONSE TO GLUCAGON STIMULUS 7 38 1.834e-07 1.935e-06
442 LEUKOCYTE CELL CELL ADHESION 15 255 1.901e-07 2.002e-06
443 POSITIVE REGULATION OF PROTEIN IMPORT INTO NUCLEUS TRANSLOCATION 5 13 1.972e-07 2.071e-06
444 CELLULAR RESPONSE TO PROSTAGLANDIN STIMULUS 6 24 2.044e-07 2.143e-06
445 ENDOTHELIAL CELL MIGRATION 8 57 2.176e-07 2.276e-06
446 PEPTIDYL TYROSINE AUTOPHOSPHORYLATION 7 39 2.215e-07 2.31e-06
447 NEGATIVE REGULATION OF TRANSPORT 20 458 2.281e-07 2.374e-06
448 REGULATED EXOCYTOSIS 14 224 2.352e-07 2.443e-06
449 NEGATIVE REGULATION OF CELL PROLIFERATION 24 643 2.463e-07 2.552e-06
450 REGULATION OF CELLULAR COMPONENT SIZE 17 337 2.588e-07 2.675e-06
451 NEGATIVE REGULATION OF VASCULATURE DEVELOPMENT 9 80 2.646e-07 2.73e-06
452 REGENERATION 12 161 2.656e-07 2.734e-06
453 POSITIVE REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 6 25 2.665e-07 2.738e-06
454 ODONTOGENESIS 10 105 2.78e-07 2.85e-06
455 CELL CYCLE CHECKPOINT 13 194 2.884e-07 2.949e-06
456 NEGATIVE REGULATION OF PHOSPHORYLATION 19 422 2.91e-07 2.97e-06
457 POSITIVE REGULATION OF LEUKOCYTE CHEMOTAXIS 9 81 2.948e-07 3.002e-06
458 ANTIGEN RECEPTOR MEDIATED SIGNALING PATHWAY 13 195 3.06e-07 3.109e-06
459 LYMPHOCYTE ACTIVATION 17 342 3.184e-07 3.227e-06
460 MESODERMAL CELL DIFFERENTIATION 6 26 3.433e-07 3.472e-06
461 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 13 197 3.441e-07 3.473e-06
462 CELL GROWTH 11 135 3.451e-07 3.476e-06
463 REPRODUCTION 36 1297 3.592e-07 3.609e-06
464 REGULATION OF SYNAPSE STRUCTURE OR ACTIVITY 14 232 3.607e-07 3.617e-06
465 REGULATION OF CELL CYCLE ARREST 10 108 3.625e-07 3.627e-06
466 POSITIVE REGULATION OF LEUKOCYTE PROLIFERATION 11 136 3.718e-07 3.705e-06
467 GLIAL CELL DIFFERENTIATION 11 136 3.718e-07 3.705e-06
468 OVARIAN FOLLICLE DEVELOPMENT 8 61 3.733e-07 3.712e-06
469 POSITIVE REGULATION OF GLUCOSE TRANSPORT 7 42 3.776e-07 3.746e-06
470 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 13 199 3.863e-07 3.825e-06
471 RESPONSE TO ALKALOID 11 137 4.004e-07 3.955e-06
472 FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 9 84 4.042e-07 3.984e-06
473 HETEROTYPIC CELL CELL ADHESION 6 27 4.372e-07 4.301e-06
474 CELL MIGRATION INVOLVED IN SPROUTING ANGIOGENESIS 5 15 4.518e-07 4.435e-06
475 MITOTIC CELL CYCLE CHECKPOINT 11 139 4.633e-07 4.539e-06
476 RESPONSE TO OSMOTIC STRESS 8 63 4.817e-07 4.708e-06
477 REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 17 354 5.157e-07 5.031e-06
478 REGULATION OF LEUKOCYTE PROLIFERATION 13 206 5.734e-07 5.582e-06
479 REGULATION OF ORGAN MORPHOGENESIS 14 242 6.005e-07 5.833e-06
480 OVULATION CYCLE PROCESS 9 88 6.036e-07 5.839e-06
481 NEGATIVE REGULATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 9 88 6.036e-07 5.839e-06
482 CELLULAR RESPONSE TO OXYGEN LEVELS 11 143 6.16e-07 5.922e-06
483 RAS PROTEIN SIGNAL TRANSDUCTION 11 143 6.16e-07 5.922e-06
484 REGULATION OF REACTIVE OXYGEN SPECIES BIOSYNTHETIC PROCESS 8 65 6.159e-07 5.922e-06
485 EXOCRINE SYSTEM DEVELOPMENT 7 45 6.173e-07 5.922e-06
486 NEGATIVE REGULATION OF CATALYTIC ACTIVITY 27 829 6.212e-07 5.947e-06
487 TOR SIGNALING 5 16 6.512e-07 6.209e-06
488 BRANCHING INVOLVED IN SALIVARY GLAND MORPHOGENESIS 5 16 6.512e-07 6.209e-06
489 RESPONSE TO TRANSFORMING GROWTH FACTOR BETA 11 144 6.605e-07 6.272e-06
490 NEGATIVE REGULATION OF CELL PROJECTION ORGANIZATION 11 144 6.605e-07 6.272e-06
491 EPITHELIAL CELL PROLIFERATION 9 89 6.65e-07 6.302e-06
492 LYMPHOCYTE DIFFERENTIATION 13 209 6.758e-07 6.391e-06
493 REGULATION OF CATABOLIC PROCESS 25 731 6.914e-07 6.525e-06
494 REGULATION OF HOMEOSTATIC PROCESS 19 447 6.957e-07 6.553e-06
495 POSTTRANSCRIPTIONAL REGULATION OF GENE EXPRESSION 19 448 7.194e-07 6.763e-06
496 T CELL RECEPTOR SIGNALING PATHWAY 11 146 7.581e-07 7.111e-06
497 REGULATION OF METAL ION TRANSPORT 16 325 8.124e-07 7.606e-06
498 RESPONSE TO ANTIBIOTIC 7 47 8.395e-07 7.844e-06
499 REGULATION OF ION TRANSPORT 22 592 8.65e-07 8.066e-06
500 POSITIVE REGULATION OF CELL GROWTH 11 148 8.681e-07 8.078e-06
501 ORGAN GROWTH 8 68 8.764e-07 8.105e-06
502 INFLAMMATORY RESPONSE 19 454 8.779e-07 8.105e-06
503 REGULATION OF NEUROLOGICAL SYSTEM PROCESS 8 68 8.764e-07 8.105e-06
504 REGULATION OF TOR SIGNALING 8 68 8.764e-07 8.105e-06
505 SKELETAL SYSTEM DEVELOPMENT 19 455 9.072e-07 8.359e-06
506 POSITIVE REGULATION OF GLYCOGEN METABOLIC PROCESS 5 17 9.142e-07 8.406e-06
507 MEMBRANE ORGANIZATION 28 899 9.178e-07 8.423e-06
508 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO PLASMA MEMBRANE 7 48 9.736e-07 8.918e-06
509 LEUKOCYTE ACTIVATION 18 414 9.999e-07 9.141e-06
510 EPIDERMIS DEVELOPMENT 14 253 1.022e-06 9.321e-06
511 HOMEOSTASIS OF NUMBER OF CELLS WITHIN A TISSUE 6 31 1.048e-06 9.522e-06
512 REGULATION OF PLATELET ACTIVATION 6 31 1.048e-06 9.522e-06
513 REGULATION OF DNA BIOSYNTHETIC PROCESS 9 94 1.061e-06 9.62e-06
514 REGULATION OF MITOCHONDRION ORGANIZATION 13 218 1.088e-06 9.828e-06
515 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 13 218 1.088e-06 9.828e-06
516 FC GAMMA RECEPTOR SIGNALING PATHWAY 9 95 1.16e-06 1.046e-05
517 REGULATION OF CELL MATURATION 5 18 1.254e-06 1.125e-05
518 REGULATION OF COLLATERAL SPROUTING 5 18 1.254e-06 1.125e-05
519 CELLULAR RESPONSE TO PROSTAGLANDIN E STIMULUS 5 18 1.254e-06 1.125e-05
520 REGULATION OF LEUKOCYTE CHEMOTAXIS 9 96 1.268e-06 1.135e-05
521 REGULATION OF CELL CYCLE PROCESS 21 558 1.272e-06 1.136e-05
522 SALIVARY GLAND DEVELOPMENT 6 32 1.278e-06 1.139e-05
523 REGULATION OF DEFENSE RESPONSE 25 759 1.367e-06 1.216e-05
524 REGULATION OF CYCLIN DEPENDENT PROTEIN KINASE ACTIVITY 9 97 1.384e-06 1.229e-05
525 POSITIVE REGULATION OF MITOTIC NUCLEAR DIVISION 7 51 1.488e-06 1.316e-05
526 CELLULAR RESPONSE TO FATTY ACID 7 51 1.488e-06 1.316e-05
527 NEGATIVE REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 9 98 1.51e-06 1.333e-05
528 REGULATION OF WOUND HEALING 10 126 1.515e-06 1.334e-05
529 HIPPOCAMPUS DEVELOPMENT 8 73 1.519e-06 1.334e-05
530 REGULATION OF ORGAN GROWTH 8 73 1.519e-06 1.334e-05
531 REGULATION OF ANATOMICAL STRUCTURE SIZE 19 472 1.563e-06 1.369e-05
532 ASTROCYTE DEVELOPMENT 5 19 1.687e-06 1.475e-05
533 AGING 14 264 1.691e-06 1.476e-05
534 REGULATION OF LIPID BIOSYNTHETIC PROCESS 10 128 1.75e-06 1.524e-05
535 RESPONSE TO PROSTAGLANDIN 6 34 1.861e-06 1.619e-05
536 REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS 13 229 1.886e-06 1.637e-05
537 REGULATION OF MORPHOGENESIS OF A BRANCHING STRUCTURE 7 53 1.944e-06 1.681e-05
538 MAMMARY GLAND EPITHELIUM DEVELOPMENT 7 53 1.944e-06 1.681e-05
539 REGULATION OF HOMOTYPIC CELL CELL ADHESION 15 307 1.986e-06 1.714e-05
540 GLIAL CELL DEVELOPMENT 8 76 2.071e-06 1.785e-05
541 REGULATION OF PEPTIDASE ACTIVITY 17 392 2.089e-06 1.796e-05
542 ORGANOPHOSPHATE METABOLIC PROCESS 27 885 2.159e-06 1.852e-05
543 POSITIVE REGULATION OF LEUKOCYTE DIFFERENTIATION 10 131 2.161e-06 1.852e-05
544 CELLULAR RESPONSE TO GROWTH HORMONE STIMULUS 5 20 2.229e-06 1.903e-05
545 REGULATION OF NEURON PROJECTION REGENERATION 5 20 2.229e-06 1.903e-05
546 POSITIVE REGULATION OF HEMOPOIESIS 11 163 2.249e-06 1.916e-05
547 RESPONSE TO ENDOPLASMIC RETICULUM STRESS 13 233 2.285e-06 1.944e-05
548 RESPONSE TO OXIDATIVE STRESS 16 352 2.301e-06 1.954e-05
549 IMMUNE EFFECTOR PROCESS 19 486 2.399e-06 2.033e-05
550 POSITIVE REGULATION OF PROTEIN IMPORT 9 104 2.488e-06 2.105e-05
551 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 42 1784 2.631e-06 2.222e-05
552 NEUROMUSCULAR JUNCTION DEVELOPMENT 6 36 2.646e-06 2.23e-05
553 INTERACTION WITH HOST 10 134 2.654e-06 2.233e-05
554 SYSTEM PROCESS 42 1785 2.669e-06 2.242e-05
555 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 7 56 2.843e-06 2.384e-05
556 SECRETION 21 588 2.902e-06 2.424e-05
557 POSITIVE REGULATION OF ADHERENS JUNCTION ORGANIZATION 5 21 2.899e-06 2.424e-05
558 RESPONSE TO CARBOHYDRATE 11 168 3.018e-06 2.517e-05
559 RESPONSE TO ETHANOL 10 136 3.034e-06 2.525e-05
560 CELLULAR RESPONSE TO MECHANICAL STIMULUS 8 80 3.065e-06 2.546e-05
561 REGULATION OF PROTEIN AUTOPHOSPHORYLATION 6 37 3.129e-06 2.595e-05
562 APOPTOTIC MITOCHONDRIAL CHANGES 7 57 3.211e-06 2.658e-05
563 RESPONSE TO TOXIC SUBSTANCE 13 241 3.316e-06 2.74e-05
564 REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 9 108 3.408e-06 2.812e-05
565 PLACENTA DEVELOPMENT 10 138 3.461e-06 2.85e-05
566 TISSUE HOMEOSTASIS 11 171 3.583e-06 2.945e-05
567 POSITIVE REGULATION OF CYTOPLASMIC TRANSPORT 14 282 3.651e-06 2.996e-05
568 REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 6 38 3.681e-06 3.01e-05
569 RESPONSE TO HYDROGEN PEROXIDE 9 109 3.679e-06 3.01e-05
570 REGULATION OF CYTOSKELETON ORGANIZATION 19 502 3.838e-06 3.133e-05
571 REGULATION OF SYNAPTIC PLASTICITY 10 140 3.939e-06 3.21e-05
572 NEURON MIGRATION 9 110 3.969e-06 3.229e-05
573 STRIATED MUSCLE CELL DIFFERENTIATION 11 173 4.009e-06 3.255e-05
574 REGULATION OF EPITHELIAL CELL APOPTOTIC PROCESS 7 59 4.066e-06 3.296e-05
575 EYE DEVELOPMENT 15 326 4.141e-06 3.351e-05
576 COLUMNAR CUBOIDAL EPITHELIAL CELL DIFFERENTIATION 9 111 4.278e-06 3.456e-05
577 ASTROCYTE DIFFERENTIATION 6 39 4.31e-06 3.476e-05
578 POSITIVE REGULATION OF CYTOKINE PRODUCTION 16 370 4.357e-06 3.507e-05
579 LEUKOCYTE HOMEOSTASIS 7 60 4.559e-06 3.664e-05
580 POSITIVE REGULATION OF NEUROLOGICAL SYSTEM PROCESS 5 23 4.707e-06 3.763e-05
581 LEUKOCYTE APOPTOTIC PROCESS 5 23 4.707e-06 3.763e-05
582 NEUROTROPHIN SIGNALING PATHWAY 5 23 4.707e-06 3.763e-05
583 EPHRIN RECEPTOR SIGNALING PATHWAY 8 85 4.851e-06 3.871e-05
584 HEART MORPHOGENESIS 12 212 4.863e-06 3.875e-05
585 OVULATION CYCLE 9 113 4.958e-06 3.943e-05
586 POSITIVE REGULATION OF STEM CELL PROLIFERATION 7 61 5.102e-06 4.051e-05
587 SYNAPSE ORGANIZATION 10 145 5.393e-06 4.275e-05
588 POSITIVE REGULATION OF NUCLEAR DIVISION 7 62 5.697e-06 4.509e-05
589 POSITIVE REGULATION OF KIDNEY DEVELOPMENT 6 41 5.83e-06 4.606e-05
590 BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 5 24 5.892e-06 4.631e-05
591 POSITIVE REGULATION OF CELL JUNCTION ASSEMBLY 5 24 5.892e-06 4.631e-05
592 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 12 216 5.888e-06 4.631e-05
593 NEGATIVE REGULATION OF PROTEIN MODIFICATION PROCESS 21 616 5.954e-06 4.671e-05
594 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 10 147 6.093e-06 4.773e-05
595 FEMALE SEX DIFFERENTIATION 9 116 6.151e-06 4.81e-05
596 REGULATION OF COAGULATION 8 88 6.296e-06 4.907e-05
597 POSITIVE REGULATION OF PEPTIDYL SERINE PHOSPHORYLATION 8 88 6.296e-06 4.907e-05
598 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 16 381 6.31e-06 4.91e-05
599 DIGESTIVE SYSTEM DEVELOPMENT 10 148 6.471e-06 5.019e-05
600 RESPONSE TO TRANSITION METAL NANOPARTICLE 10 148 6.471e-06 5.019e-05
601 NEGATIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 9 117 6.6e-06 5.109e-05
602 REGULATION OF MYELOID CELL DIFFERENTIATION 11 183 6.873e-06 5.312e-05
603 HEMIDESMOSOME ASSEMBLY 4 12 6.943e-06 5.358e-05
604 POSITIVE REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 13 258 6.963e-06 5.364e-05
605 MESODERM DEVELOPMENT 9 118 7.076e-06 5.442e-05
606 RESPONSE TO PROSTAGLANDIN E 5 25 7.298e-06 5.604e-05
607 CEREBRAL CORTEX CELL MIGRATION 6 43 7.76e-06 5.948e-05
608 REGULATION OF DENDRITE DEVELOPMENT 9 120 8.118e-06 6.213e-05
609 NEGATIVE REGULATION OF CELL DEVELOPMENT 14 303 8.314e-06 6.352e-05
610 REGULATION OF MULTICELLULAR ORGANISM GROWTH 7 66 8.688e-06 6.616e-05
611 MESODERM MORPHOGENESIS 7 66 8.688e-06 6.616e-05
612 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 22 684 8.882e-06 6.753e-05
613 DEVELOPMENTAL PROGRAMMED CELL DEATH 5 26 8.954e-06 6.786e-05
614 NEGATIVE REGULATION OF LIPID TRANSPORT 5 26 8.954e-06 6.786e-05
615 SECRETION BY CELL 18 486 9.348e-06 7.073e-05
616 REGULATION OF PROTEIN TARGETING 14 307 9.645e-06 7.285e-05
617 PHAGOCYTOSIS 11 190 9.815e-06 7.402e-05
618 INDUCTION OF POSITIVE CHEMOTAXIS 4 13 9.941e-06 7.437e-05
619 REGULATION OF CELL PROLIFERATION INVOLVED IN KIDNEY DEVELOPMENT 4 13 9.941e-06 7.437e-05
620 CELLULAR RESPONSE TO HEPATOCYTE GROWTH FACTOR STIMULUS 4 13 9.941e-06 7.437e-05
621 RESPONSE TO HEPATOCYTE GROWTH FACTOR 4 13 9.941e-06 7.437e-05
622 T CELL DIFFERENTIATION 9 123 9.926e-06 7.437e-05
623 POSITIVE REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 12 228 1.019e-05 7.611e-05
624 NEGATIVE REGULATION OF NEURON DIFFERENTIATION 11 191 1.031e-05 7.667e-05
625 BONE DEVELOPMENT 10 156 1.031e-05 7.667e-05
626 RESPONSE TO REACTIVE OXYGEN SPECIES 11 191 1.031e-05 7.667e-05
627 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 15 352 1.04e-05 7.716e-05
628 MULTICELLULAR ORGANISMAL RESPONSE TO STRESS 7 68 1.061e-05 7.863e-05
629 EXOCYTOSIS 14 310 1.076e-05 7.962e-05
630 REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 5 27 1.089e-05 8.03e-05
631 POSITIVE REGULATION OF MESENCHYMAL CELL PROLIFERATION 5 27 1.089e-05 8.03e-05
632 PEPTIDYL THREONINE MODIFICATION 6 46 1.159e-05 8.536e-05
633 SIGNAL TRANSDUCTION IN RESPONSE TO DNA DAMAGE 8 96 1.203e-05 8.846e-05
634 RESPONSE TO UV 9 126 1.207e-05 8.857e-05
635 REGULATION OF INNATE IMMUNE RESPONSE 15 357 1.229e-05 9.002e-05
636 SIGNAL TRANSDUCTION BY P53 CLASS MEDIATOR 9 127 1.286e-05 9.411e-05
637 ORGANOPHOSPHATE BIOSYNTHETIC PROCESS 17 450 1.292e-05 9.437e-05
638 LONG TERM MEMORY 5 28 1.314e-05 9.581e-05
639 NEGATIVE REGULATION OF RESPONSE TO EXTERNAL STIMULUS 13 274 1.326e-05 9.655e-05
640 POSITIVE REGULATION OF METANEPHROS DEVELOPMENT 4 14 1.38e-05 9.999e-05
641 POSITIVE REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 4 14 1.38e-05 9.999e-05
642 POSITIVE REGULATION OF SPROUTING ANGIOGENESIS 4 14 1.38e-05 9.999e-05
643 EMBRYONIC ORGAN DEVELOPMENT 16 406 1.392e-05 0.0001008
644 SKIN EPIDERMIS DEVELOPMENT 7 71 1.415e-05 0.0001023
645 POSITIVE REGULATION OF ION TRANSPORT 12 236 1.44e-05 0.0001039
646 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 9 129 1.459e-05 0.0001051
647 PROTEIN COMPLEX SUBUNIT ORGANIZATION 36 1527 1.496e-05 0.0001076
648 MUSCLE CELL DIFFERENTIATION 12 237 1.502e-05 0.0001079
649 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 19 554 1.548e-05 0.000111
650 ENERGY RESERVE METABOLIC PROCESS 7 72 1.553e-05 0.0001112
651 REGULATION OF SEQUENCE SPECIFIC DNA BINDING TRANSCRIPTION FACTOR ACTIVITY 15 365 1.594e-05 0.000114
652 REGULATION OF PROTEOLYSIS 22 711 1.618e-05 0.0001155
653 MITOTIC DNA INTEGRITY CHECKPOINT 8 100 1.626e-05 0.0001158
654 LEARNING 9 131 1.651e-05 0.0001173
655 REGULATION OF SYSTEM PROCESS 18 507 1.651e-05 0.0001173
656 ASSOCIATIVE LEARNING 7 73 1.702e-05 0.0001203
657 G1 DNA DAMAGE CHECKPOINT 7 73 1.702e-05 0.0001203
658 REGULATION OF PLASMA MEMBRANE ORGANIZATION 7 73 1.702e-05 0.0001203
659 REGULATION OF EXTENT OF CELL GROWTH 8 101 1.749e-05 0.0001235
660 DEFENSE RESPONSE 31 1231 1.808e-05 0.0001274
661 NEGATIVE REGULATION OF DENDRITE MORPHOGENESIS 4 15 1.865e-05 0.0001307
662 POSITIVE REGULATION OF MITOCHONDRION ORGANIZATION 10 167 1.868e-05 0.0001307
663 RESPONSE TO GROWTH HORMONE 5 30 1.871e-05 0.0001307
664 NEGATIVE REGULATION OF TOR SIGNALING 5 30 1.871e-05 0.0001307
665 CARDIAC MUSCLE CELL DIFFERENTIATION 7 74 1.862e-05 0.0001307
666 NEUROTROPHIN TRK RECEPTOR SIGNALING PATHWAY 4 15 1.865e-05 0.0001307
667 LYMPHOCYTE HOMEOSTASIS 6 50 1.895e-05 0.0001316
668 STAT CASCADE 6 50 1.895e-05 0.0001316
669 JAK STAT CASCADE 6 50 1.895e-05 0.0001316
670 VISUAL BEHAVIOR 6 50 1.895e-05 0.0001316
671 REGULATION OF CYTOKINE PRODUCTION 19 563 1.934e-05 0.0001341
672 RESPONSE TO BIOTIC STIMULUS 25 886 1.997e-05 0.0001383
673 REGULATION OF MUSCLE ORGAN DEVELOPMENT 8 103 2.019e-05 0.0001396
674 VESICLE MEDIATED TRANSPORT 31 1239 2.049e-05 0.0001414
675 DEVELOPMENTAL GROWTH INVOLVED IN MORPHOGENESIS 8 104 2.166e-05 0.0001493
676 NEGATIVE REGULATION OF CELLULAR RESPONSE TO INSULIN STIMULUS 5 31 2.21e-05 0.0001521
677 REGULATION OF CALCIUM ION TRANSPORT 11 209 2.393e-05 0.0001645
678 POSITIVE REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING PATHWAY 4 16 2.465e-05 0.0001689
679 REGULATION OF DEVELOPMENTAL PIGMENTATION 4 16 2.465e-05 0.0001689
680 POSITIVE REGULATION OF CALCIUM ION TRANSPORT 8 106 2.488e-05 0.0001698
681 INNATE IMMUNE RESPONSE ACTIVATING CELL SURFACE RECEPTOR SIGNALING PATHWAY 8 106 2.488e-05 0.0001698
682 REGULATION OF GLUCOSE METABOLIC PROCESS 8 106 2.488e-05 0.0001698
683 PROTEIN COMPLEX BIOGENESIS 29 1132 2.533e-05 0.0001723
684 PROTEIN COMPLEX ASSEMBLY 29 1132 2.533e-05 0.0001723
685 NEGATIVE REGULATION OF KINASE ACTIVITY 12 250 2.55e-05 0.0001732
686 NEGATIVE REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY IN ABSENCE OF LIGAND 5 32 2.596e-05 0.0001756
687 REGULATION OF ACTIN CYTOSKELETON REORGANIZATION 5 32 2.596e-05 0.0001756
688 NEGATIVE REGULATION OF SIGNAL TRANSDUCTION IN ABSENCE OF LIGAND 5 32 2.596e-05 0.0001756
689 REGULATION OF CELL SHAPE 9 139 2.65e-05 0.000179
690 NEGATIVE REGULATION OF CELL SUBSTRATE ADHESION 6 53 2.663e-05 0.0001793
691 NEGATIVE REGULATION OF AUTOPHAGY 6 53 2.663e-05 0.0001793
692 CARDIAC MUSCLE TISSUE DEVELOPMENT 9 140 2.805e-05 0.0001886
693 MULTI MULTICELLULAR ORGANISM PROCESS 11 213 2.85e-05 0.0001914
694 NEGATIVE REGULATION OF CELL CYCLE PROCESS 11 214 2.976e-05 0.0001995
695 REGULATION OF MYELINATION 5 33 3.032e-05 0.0002027
696 RESPONSE TO VITAMIN D 5 33 3.032e-05 0.0002027
697 REGULATION OF RHO PROTEIN SIGNAL TRANSDUCTION 8 109 3.046e-05 0.0002034
698 POSITIVE REGULATION OF NUCLEOTIDE CATABOLIC PROCESS 4 17 3.195e-05 0.000213
699 REGULATION OF OSSIFICATION 10 178 3.235e-05 0.0002153
700 REGULATION OF KIDNEY DEVELOPMENT 6 55 3.301e-05 0.0002194
701 POSITIVE REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 8 111 3.474e-05 0.0002306
702 REGULATION OF MESENCHYMAL CELL PROLIFERATION 5 34 3.522e-05 0.0002334
703 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 11 218 3.526e-05 0.0002334
704 RESPONSE TO IONIZING RADIATION 9 145 3.701e-05 0.0002442
705 SINGLE ORGANISM BIOSYNTHETIC PROCESS 32 1340 3.703e-05 0.0002442
706 REGULATION OF OSTEOBLAST DIFFERENTIATION 8 112 3.705e-05 0.0002442
707 NEGATIVE REGULATION OF CELL CYCLE PHASE TRANSITION 9 146 3.907e-05 0.0002567
708 DNA INTEGRITY CHECKPOINT 9 146 3.907e-05 0.0002567
709 ORGAN REGENERATION 7 83 3.946e-05 0.0002579
710 HAIR CYCLE 7 83 3.946e-05 0.0002579
711 MOLTING CYCLE 7 83 3.946e-05 0.0002579
712 RESPONSE TO FATTY ACID 7 83 3.946e-05 0.0002579
713 REGULATION OF PROTEIN STABILITY 11 221 3.995e-05 0.0002607
714 RESPONSE TO PLATELET DERIVED GROWTH FACTOR 4 18 4.072e-05 0.000265
715 LYMPHOCYTE APOPTOTIC PROCESS 4 18 4.072e-05 0.000265
716 CARTILAGE DEVELOPMENT 9 147 4.122e-05 0.0002679
717 CELLULAR RESPONSE TO OXIDATIVE STRESS 10 184 4.289e-05 0.0002783
718 CELLULAR RESPONSE TO ALCOHOL 8 115 4.479e-05 0.0002903
719 POSITIVE REGULATION OF CELL CYCLE ARREST 7 85 4.604e-05 0.0002979
720 SEX DIFFERENTIATION 12 266 4.671e-05 0.0003018
721 REGULATION OF NUCLEOTIDE CATABOLIC PROCESS 5 36 4.687e-05 0.000302
722 POSITIVE REGULATION OF GLUCOSE METABOLIC PROCESS 5 36 4.687e-05 0.000302
723 CELLULAR MACROMOLECULE LOCALIZATION 30 1234 4.804e-05 0.0003091
724 POSITIVE REGULATION OF DNA BIOSYNTHETIC PROCESS 6 59 4.944e-05 0.0003173
725 VASCULOGENESIS 6 59 4.944e-05 0.0003173
726 KIDNEY VASCULATURE DEVELOPMENT 4 19 5.113e-05 0.0003272
727 RENAL SYSTEM VASCULATURE DEVELOPMENT 4 19 5.113e-05 0.0003272
728 REGULATION OF ACTIN FILAMENT BASED PROCESS 13 312 5.131e-05 0.0003279
729 TISSUE REMODELING 7 87 5.349e-05 0.0003414
730 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO CELL PERIPHERY 5 37 5.37e-05 0.0003418
731 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO PLASMA MEMBRANE 5 37 5.37e-05 0.0003418
732 MATERNAL PROCESS INVOLVED IN FEMALE PREGNANCY 6 60 5.442e-05 0.0003459
733 PROTEIN DEPHOSPHORYLATION 10 190 5.624e-05 0.000356
734 MESENCHYME DEVELOPMENT 10 190 5.624e-05 0.000356
735 STEM CELL DIFFERENTIATION 10 190 5.624e-05 0.000356
736 GLUCOSE METABOLIC PROCESS 8 119 5.718e-05 0.0003615
737 REGULATION OF STEM CELL PROLIFERATION 7 88 5.756e-05 0.0003634
738 MULTICELLULAR ORGANISMAL HOMEOSTASIS 12 272 5.79e-05 0.0003651
739 POSITIVE REGULATION OF PEPTIDASE ACTIVITY 9 154 5.926e-05 0.0003731
740 CELLULAR RESPONSE TO DNA DAMAGE STIMULUS 21 720 5.966e-05 0.0003751
741 ENDOCYTOSIS 17 509 6.093e-05 0.0003826
742 POSITIVE REGULATION OF PROTEOLYSIS 14 363 6.103e-05 0.0003827
743 POSITIVE REGULATION OF ORGAN GROWTH 5 38 6.128e-05 0.0003837
744 RESPONSE TO HEAT 7 89 6.189e-05 0.0003871
745 POSITIVE REGULATION OF DEFENSE RESPONSE 14 364 6.285e-05 0.0003925
746 EMBRYONIC HEMOPOIESIS 4 20 6.335e-05 0.0003952
747 MUSCLE TISSUE DEVELOPMENT 12 275 6.433e-05 0.0004007
748 FOREBRAIN CELL MIGRATION 6 62 6.56e-05 0.0004075
749 REGULATION OF TISSUE REMODELING 6 62 6.56e-05 0.0004075
750 REGULATION OF VESICLE MEDIATED TRANSPORT 16 462 6.592e-05 0.000409
751 MIDBRAIN DEVELOPMENT 7 90 6.648e-05 0.0004114
752 MESONEPHROS DEVELOPMENT 7 90 6.648e-05 0.0004114
753 CELLULAR RESPONSE TO NUTRIENT 5 39 6.966e-05 0.0004304
754 EAR DEVELOPMENT 10 195 6.993e-05 0.0004315
755 REGULATION OF OSTEOCLAST DIFFERENTIATION 6 63 7.184e-05 0.0004427
756 NEGATIVE REGULATION OF GROWTH 11 236 7.231e-05 0.0004444
757 ENDOCRINE SYSTEM DEVELOPMENT 8 123 7.228e-05 0.0004444
758 CELLULAR HOMEOSTASIS 20 676 7.404e-05 0.0004545
759 CELLULAR CHEMICAL HOMEOSTASIS 18 570 7.574e-05 0.0004643
760 B CELL HOMEOSTASIS 4 21 7.758e-05 0.000475
761 REGULATION OF TRANSPORTER ACTIVITY 10 198 7.942e-05 0.0004856
762 KIDNEY EPITHELIUM DEVELOPMENT 8 125 8.099e-05 0.0004946
763 REGULATION OF ENDOCYTOSIS 10 199 8.282e-05 0.0005051
764 PROSTATE GLAND DEVELOPMENT 5 41 8.904e-05 0.0005423
765 ANATOMICAL STRUCTURE HOMEOSTASIS 12 285 9.038e-05 0.0005497
766 REGULATION OF TRANSMEMBRANE TRANSPORT 15 426 9.293e-05 0.0005645
767 ACTIVATION OF CYSTEINE TYPE ENDOPEPTIDASE ACTIVITY 7 95 9.381e-05 0.0005665
768 TRANSFORMING GROWTH FACTOR BETA RECEPTOR SIGNALING PATHWAY 7 95 9.381e-05 0.0005665
769 DEPHOSPHORYLATION 12 286 9.342e-05 0.0005665
770 SOMATIC STEM CELL DIVISION 4 22 9.399e-05 0.0005665
771 ACTIVATION OF PROTEIN KINASE B ACTIVITY 4 22 9.399e-05 0.0005665
772 ERK1 AND ERK2 CASCADE 4 22 9.399e-05 0.0005665
773 REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION TO MITOCHONDRION 8 128 9.568e-05 0.000576
774 NEGATIVE REGULATION OF CATABOLIC PROCESS 10 203 9.768e-05 0.0005872
775 RESPONSE TO METAL ION 13 333 9.908e-05 0.0005949
776 REGULATION OF CELLULAR CARBOHYDRATE CATABOLIC PROCESS 5 42 0.0001002 0.0005996
777 CARDIOCYTE DIFFERENTIATION 7 96 0.0001002 0.0005996
778 REGULATION OF CARBOHYDRATE CATABOLIC PROCESS 5 42 0.0001002 0.0005996
779 NEGATIVE REGULATION OF PEPTIDASE ACTIVITY 11 245 0.0001009 0.0006027
780 CELL AGING 6 67 0.0001017 0.0006061
781 ACTIVATION OF INNATE IMMUNE RESPONSE 10 204 0.0001017 0.0006061
782 RESPONSE TO INCREASED OXYGEN LEVELS 4 23 0.0001128 0.0006677
783 PROTEIN STABILIZATION 8 131 0.0001125 0.0006677
784 REGULATION OF METANEPHROS DEVELOPMENT 4 23 0.0001128 0.0006677
785 RESPONSE TO HYPEROXIA 4 23 0.0001128 0.0006677
786 REGULATION OF INSULIN RECEPTOR SIGNALING PATHWAY 5 43 0.0001123 0.0006677
787 REGULATION OF AUTOPHAGY 11 249 0.0001164 0.0006884
788 B CELL ACTIVATION 8 132 0.0001186 0.0007006
789 NEGATIVE REGULATION OF LIPID BIOSYNTHETIC PROCESS 5 44 0.0001256 0.0007387
790 BRANCHING INVOLVED IN URETERIC BUD MORPHOGENESIS 5 44 0.0001256 0.0007387
791 REGULATION OF RELEASE OF CYTOCHROME C FROM MITOCHONDRIA 5 44 0.0001256 0.0007387
792 MITOCHONDRION ORGANIZATION 18 594 0.0001271 0.0007467
793 CELLULAR PROCESS INVOLVED IN REPRODUCTION IN MULTICELLULAR ORGANISM 11 252 0.0001294 0.0007591
794 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 6 70 0.0001299 0.0007614
795 MESENCHYMAL CELL DIFFERENTIATION 8 134 0.0001317 0.000771
796 FOCAL ADHESION ASSEMBLY 4 24 0.0001342 0.0007804
797 AXON REGENERATION 4 24 0.0001342 0.0007804
798 POSITIVE REGULATION OF NUCLEOSIDE METABOLIC PROCESS 4 24 0.0001342 0.0007804
799 POSITIVE REGULATION OF ATP METABOLIC PROCESS 4 24 0.0001342 0.0007804
800 CELL SUBSTRATE ADHERENS JUNCTION ASSEMBLY 4 24 0.0001342 0.0007804
801 LUNG MORPHOGENESIS 5 45 0.00014 0.0008112
802 MODIFICATION BY SYMBIONT OF HOST MORPHOLOGY OR PHYSIOLOGY 5 45 0.00014 0.0008112
803 ENDOCHONDRAL BONE MORPHOGENESIS 5 45 0.00014 0.0008112
804 POSITIVE REGULATION OF CATABOLIC PROCESS 14 395 0.0001487 0.0008607
805 MODULATION OF SYNAPTIC TRANSMISSION 12 301 0.0001509 0.0008721
806 CELLULAR RESPONSE TO RADIATION 8 137 0.0001536 0.0008865
807 REGULATION OF MUSCLE TISSUE DEVELOPMENT 7 103 0.000156 0.0008986
808 STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 7 103 0.000156 0.0008986
809 CELLULAR EXTRAVASATION 4 25 0.0001583 0.0009096
810 HISTONE PHOSPHORYLATION 4 25 0.0001583 0.0009096
811 CELLULAR RESPONSE TO KETONE 6 73 0.0001641 0.0009414
812 NEGATIVE REGULATION OF TRANSFERASE ACTIVITY 13 351 0.0001669 0.0009561
813 REGULATION OF DENDRITE MORPHOGENESIS 6 74 0.0001769 0.001013
814 CYTOKINE MEDIATED SIGNALING PATHWAY 15 452 0.0001778 0.001016
815 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 11 262 0.0001817 0.001038
816 REPLACEMENT OSSIFICATION 4 26 0.0001855 0.001055
817 ENDOCHONDRAL OSSIFICATION 4 26 0.0001855 0.001055
818 CELLULAR RESPONSE TO VITAMIN 4 26 0.0001855 0.001055
819 FAT CELL DIFFERENTIATION 7 106 0.0001866 0.00106
820 BIOMINERAL TISSUE DEVELOPMENT 6 75 0.0001905 0.001081
821 COLUMNAR CUBOIDAL EPITHELIAL CELL DEVELOPMENT 5 48 0.000191 0.001082
822 REGULATION OF T CELL DIFFERENTIATION 7 107 0.0001978 0.00112
823 REGULATION OF CELLULAR RESPONSE TO HEAT 6 76 0.000205 0.001159
824 REGULATION OF NUCLEOSIDE METABOLIC PROCESS 5 49 0.0002107 0.001189
825 REGULATION OF ATP METABOLIC PROCESS 5 49 0.0002107 0.001189
826 PROSTATE GLAND GROWTH 3 11 0.0002112 0.00119
827 PROTEIN LOCALIZATION 37 1805 0.0002117 0.001191
828 CELL DIVISION 15 460 0.0002147 0.001207
829 POSITIVE REGULATION OF HEART GROWTH 4 27 0.0002159 0.001209
830 REGULATION OF LAMELLIPODIUM ASSEMBLY 4 27 0.0002159 0.001209
831 SUBSTRATE DEPENDENT CELL MIGRATION 4 27 0.0002159 0.001209
832 REGULATION OF COENZYME METABOLIC PROCESS 5 50 0.0002321 0.001293
833 RESPONSE TO GAMMA RADIATION 5 50 0.0002321 0.001293
834 REGULATION OF COFACTOR METABOLIC PROCESS 5 50 0.0002321 0.001293
835 POSITIVE REGULATION OF MYELOID LEUKOCYTE DIFFERENTIATION 5 50 0.0002321 0.001293
836 RENAL TUBULE DEVELOPMENT 6 78 0.0002364 0.001316
837 EPITHELIAL CELL DEVELOPMENT 9 186 0.0002487 0.001381
838 REGULATION OF MACROPHAGE DERIVED FOAM CELL DIFFERENTIATION 4 28 0.0002497 0.001381
839 NEGATIVE REGULATION OF DENDRITE DEVELOPMENT 4 28 0.0002497 0.001381
840 REGULATION OF SPROUTING ANGIOGENESIS 4 28 0.0002497 0.001381
841 MAMMARY GLAND DUCT MORPHOGENESIS 4 28 0.0002497 0.001381
842 BONE MORPHOGENESIS 6 79 0.0002535 0.001401
843 RESPONSE TO NICOTINE 5 51 0.000255 0.001407
844 ESTABLISHMENT OF PROTEIN LOCALIZATION 31 1423 0.0002603 0.001435
845 RESPONSE TO TEMPERATURE STIMULUS 8 148 0.0002607 0.001436
846 ZYMOGEN ACTIVATION 7 112 0.0002622 0.001442
847 ION HOMEOSTASIS 17 576 0.0002667 0.001465
848 NEGATIVE REGULATION OF LIPID METABOLIC PROCESS 6 80 0.0002715 0.00149
849 RESPONSE TO MOLECULE OF BACTERIAL ORIGIN 12 321 0.0002727 0.001494
850 NEGATIVE REGULATION OF GENE EXPRESSION 32 1493 0.0002743 0.001501
851 REGULATION OF SYNAPSE ORGANIZATION 7 113 0.0002769 0.001512
852 PROTEIN HETEROOLIGOMERIZATION 7 113 0.0002769 0.001512
853 POSITIVE REGULATION OF INTRINSIC APOPTOTIC SIGNALING PATHWAY 5 52 0.0002796 0.001523
854 ACTIVATION OF TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 3 12 0.0002793 0.001523
855 STEM CELL DIVISION 4 29 0.0002871 0.00156
856 POSITIVE REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 4 29 0.0002871 0.00156
857 METANEPHROS DEVELOPMENT 6 81 0.0002905 0.001576
858 POSITIVE REGULATION OF MYELOID CELL DIFFERENTIATION 6 81 0.0002905 0.001576
859 REGULATION OF EMBRYONIC DEVELOPMENT 7 114 0.0002923 0.001583
860 RESPONSE TO TUMOR NECROSIS FACTOR 10 233 0.000299 0.001618
861 MESONEPHRIC TUBULE MORPHOGENESIS 5 53 0.0003059 0.001653
862 NEUROLOGICAL SYSTEM PROCESS 28 1242 0.0003065 0.001655
863 KIDNEY MORPHOGENESIS 6 82 0.0003106 0.001675
864 INTRINSIC APOPTOTIC SIGNALING PATHWAY IN RESPONSE TO DNA DAMAGE BY P53 CLASS MEDIATOR 4 30 0.0003284 0.001768
865 REGULATION OF MITOCHONDRIAL MEMBRANE POTENTIAL 5 54 0.0003341 0.001797
866 NEGATIVE REGULATION OF PROTEOLYSIS 12 329 0.0003407 0.001831
867 REGULATION OF MUSCLE SYSTEM PROCESS 9 195 0.0003524 0.001891
868 SENSORY PERCEPTION OF MECHANICAL STIMULUS 8 155 0.0003562 0.00191
869 NEURONAL STEM CELL DIVISION 3 13 0.0003602 0.001926
870 NEUROBLAST DIVISION 3 13 0.0003602 0.001926
871 REGULATION OF EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 5 55 0.0003642 0.001943
872 REGULATION OF B CELL PROLIFERATION 5 55 0.0003642 0.001943
873 SENSORY ORGAN MORPHOGENESIS 10 239 0.0003658 0.00195
874 NEGATIVE REGULATION OF CELLULAR CATABOLIC PROCESS 8 156 0.0003719 0.001978
875 NEGATIVE REGULATION OF RESPONSE TO WOUNDING 8 156 0.0003719 0.001978
876 CELLULAR RESPONSE TO GLUCOSE STARVATION 4 31 0.0003737 0.001985
877 POSITIVE REGULATION OF PROTEIN COMPLEX ASSEMBLY 9 197 0.0003797 0.002015
878 HEXOSE METABOLIC PROCESS 8 157 0.0003882 0.002057
879 REGULATION OF DENDRITIC SPINE DEVELOPMENT 5 56 0.0003963 0.002098
880 MULTICELLULAR ORGANISM REPRODUCTION 20 768 0.000398 0.002105
881 POSITIVE REGULATION OF B CELL ACTIVATION 6 86 0.0004019 0.002123
882 CARBOHYDRATE BIOSYNTHETIC PROCESS 7 121 0.00042 0.002213
883 REGULATION OF B CELL ACTIVATION 7 121 0.00042 0.002213
884 METANEPHRIC NEPHRON DEVELOPMENT 4 32 0.0004234 0.002224
885 REGULATION OF JNK CASCADE 8 159 0.0004225 0.002224
886 POSITIVE REGULATION OF MULTICELLULAR ORGANISM GROWTH 4 32 0.0004234 0.002224
887 MOVEMENT IN ENVIRONMENT OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 6 87 0.0004277 0.002226
888 NEGATIVE REGULATION OF TRANSMEMBRANE TRANSPORT 6 87 0.0004277 0.002226
889 ENTRY INTO CELL OF OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 6 87 0.0004277 0.002226
890 VIRAL ENTRY INTO HOST CELL 6 87 0.0004277 0.002226
891 ENTRY INTO OTHER ORGANISM INVOLVED IN SYMBIOTIC INTERACTION 6 87 0.0004277 0.002226
892 MOVEMENT IN HOST ENVIRONMENT 6 87 0.0004277 0.002226
893 ENTRY INTO HOST 6 87 0.0004277 0.002226
894 ENTRY INTO HOST CELL 6 87 0.0004277 0.002226
895 EPITHELIAL CELL CELL ADHESION 3 14 0.0004546 0.002351
896 LEUKOCYTE PROLIFERATION 6 88 0.0004548 0.002351
897 REGULATION OF GLOMERULUS DEVELOPMENT 3 14 0.0004546 0.002351
898 POSITIVE REGULATION OF CELL SIZE 3 14 0.0004546 0.002351
899 BONE MATURATION 3 14 0.0004546 0.002351
900 POSITIVE REGULATION OF CYTOSOLIC CALCIUM ION CONCENTRATION INVOLVED IN PHOSPHOLIPASE C ACTIVATING G PROTEIN COUPLED SIGNALING PATHWAY 3 14 0.0004546 0.002351
901 POSITIVE REGULATION OF INNATE IMMUNE RESPONSE 10 246 0.000459 0.00237
902 CELLULAR GLUCAN METABOLIC PROCESS 5 58 0.0004669 0.002406
903 GLUCAN METABOLIC PROCESS 5 58 0.0004669 0.002406
904 ESTABLISHMENT OF LOCALIZATION IN CELL 34 1676 0.000476 0.00245
905 CELLULAR SENESCENCE 4 33 0.0004776 0.00245
906 NEURON PROJECTION REGENERATION 4 33 0.0004776 0.00245
907 REGULATION OF BONE RESORPTION 4 33 0.0004776 0.00245
908 POSITIVE REGULATION OF RESPONSE TO WOUNDING 8 162 0.0004785 0.002452
909 B CELL DIFFERENTIATION 6 89 0.0004832 0.002473
910 RESPONSE TO TOPOLOGICALLY INCORRECT PROTEIN 8 163 0.0004985 0.002549
911 T CELL HOMEOSTASIS 4 34 0.0005366 0.002738
912 ADHERENS JUNCTION ASSEMBLY 4 34 0.0005366 0.002738
913 NEGATIVE REGULATION OF HYDROLASE ACTIVITY 13 397 0.0005427 0.002766
914 CELLULAR RESPONSE TO LIGHT STIMULUS 6 91 0.0005441 0.00277
915 REGULATION OF MONOOXYGENASE ACTIVITY 5 60 0.0005466 0.002776
916 CHONDROCYTE DIFFERENTIATION 5 60 0.0005466 0.002776
917 JAK STAT CASCADE INVOLVED IN GROWTH HORMONE SIGNALING PATHWAY 3 15 0.0005636 0.002844
918 NEGATIVE REGULATION OF INTERLEUKIN 12 PRODUCTION 3 15 0.0005636 0.002844
919 RESPONSE TO VITAMIN E 3 15 0.0005636 0.002844
920 T CELL LINEAGE COMMITMENT 3 15 0.0005636 0.002844
921 NEGATIVE REGULATION OF ION TRANSPORT 7 127 0.000562 0.002844
922 T CELL APOPTOTIC PROCESS 3 15 0.0005636 0.002844
923 NEGATIVE REGULATION OF ESTABLISHMENT OF PROTEIN LOCALIZATION 9 209 0.0005828 0.002938
924 CELLULAR RESPONSE TO HYDROGEN PEROXIDE 5 61 0.00059 0.002971
925 NEGATIVE REGULATION OF EPITHELIAL CELL APOPTOTIC PROCESS 4 35 0.0006006 0.003012
926 BONE REMODELING 4 35 0.0006006 0.003012
927 RESPONSE TO MINERALOCORTICOID 4 35 0.0006006 0.003012
928 RESPONSE TO IRON ION 4 35 0.0006006 0.003012
929 INTRACELLULAR RECEPTOR SIGNALING PATHWAY 8 168 0.0006086 0.003048
930 NEPHRON EPITHELIUM DEVELOPMENT 6 93 0.0006109 0.003056
931 REGULATION OF NUCLEOTIDE METABOLIC PROCESS 9 211 0.000624 0.003115
932 NEGATIVE REGULATION OF CYTOKINE PRODUCTION 9 211 0.000624 0.003115
933 NEGATIVE REGULATION OF CELL GROWTH 8 170 0.0006579 0.003281
934 NEGATIVE REGULATION OF PROTEIN KINASE B SIGNALING 4 36 0.0006698 0.003337
935 RETINA DEVELOPMENT IN CAMERA TYPE EYE 7 131 0.0006761 0.003365
936 POSITIVE REGULATION OF ACTIN CYTOSKELETON REORGANIZATION 3 16 0.000688 0.003388
937 REGULATION OF GENE EXPRESSION BY GENETIC IMPRINTING 3 16 0.000688 0.003388
938 REGULATION OF TRANSCRIPTION FACTOR IMPORT INTO NUCLEUS 6 95 0.0006838 0.003388
939 REGULATION OF LIPID TRANSPORT 6 95 0.0006838 0.003388
940 POSITIVE REGULATION OF LAMELLIPODIUM ASSEMBLY 3 16 0.000688 0.003388
941 POSITIVE REGULATION OF TRANSFORMING GROWTH FACTOR BETA PRODUCTION 3 16 0.000688 0.003388
942 RETINA VASCULATURE DEVELOPMENT IN CAMERA TYPE EYE 3 16 0.000688 0.003388
943 POSITIVE REGULATION OF TYROSINE PHOSPHORYLATION OF STAT5 PROTEIN 3 16 0.000688 0.003388
944 REGULATION OF MUSCLE ADAPTATION 5 63 0.0006847 0.003388
945 REGULATION OF FATTY ACID BETA OXIDATION 3 16 0.000688 0.003388
946 POSITIVE REGULATION OF NF KAPPAB TRANSCRIPTION FACTOR ACTIVITY 7 132 0.0007073 0.003475
947 REGULATION OF LYMPHOCYTE DIFFERENTIATION 7 132 0.0007073 0.003475
948 MYELOID LEUKOCYTE DIFFERENTIATION 6 96 0.0007227 0.003547
949 POSITIVE REGULATION OF B CELL PROLIFERATION 4 37 0.0007445 0.003635
950 POSITIVE REGULATION OF PROTEIN TYROSINE KINASE ACTIVITY 4 37 0.0007445 0.003635
951 REGULATION OF MUSCLE HYPERTROPHY 4 37 0.0007445 0.003635
952 MODULATION BY VIRUS OF HOST MORPHOLOGY OR PHYSIOLOGY 4 37 0.0007445 0.003635
953 REGULATION OF LAMELLIPODIUM ORGANIZATION 4 37 0.0007445 0.003635
954 IN UTERO EMBRYONIC DEVELOPMENT 11 311 0.0007719 0.003765
955 NEGATIVE REGULATION OF AXONOGENESIS 5 65 0.0007902 0.00385
956 COLLAGEN FIBRIL ORGANIZATION 4 38 0.0008249 0.003999
957 BRANCH ELONGATION OF AN EPITHELIUM 3 17 0.0008286 0.003999
958 NEGATIVE REGULATION OF PLATELET ACTIVATION 3 17 0.0008286 0.003999
959 BONE MINERALIZATION 4 38 0.0008249 0.003999
960 REGULATION OF DNA METHYLATION 3 17 0.0008286 0.003999
961 NEGATIVE REGULATION OF RELEASE OF CYTOCHROME C FROM MITOCHONDRIA 3 17 0.0008286 0.003999
962 NEGATIVE REGULATION OF LIPID STORAGE 3 17 0.0008286 0.003999
963 MAMMARY GLAND ALVEOLUS DEVELOPMENT 3 17 0.0008286 0.003999
964 MAMMARY GLAND LOBULE DEVELOPMENT 3 17 0.0008286 0.003999
965 CELLULAR RESPONSE TO UV 5 66 0.0008473 0.004081
966 NEURAL NUCLEUS DEVELOPMENT 5 66 0.0008473 0.004081
967 STRIATED MUSCLE CONTRACTION 6 99 0.0008498 0.004089
968 CIRCULATORY SYSTEM PROCESS 12 366 0.000873 0.004196
969 CIRCADIAN RHYTHM 7 137 0.0008809 0.00423
970 TRABECULA MORPHOGENESIS 4 39 0.0009112 0.004344
971 MACROMOLECULAR COMPLEX ASSEMBLY 29 1398 0.0009097 0.004344
972 REGULATION OF CELL ADHESION MEDIATED BY INTEGRIN 4 39 0.0009112 0.004344
973 REGULATION OF GRANULOCYTE CHEMOTAXIS 4 39 0.0009112 0.004344
974 EXTRINSIC APOPTOTIC SIGNALING PATHWAY VIA DEATH DOMAIN RECEPTORS 4 39 0.0009112 0.004344
975 NEGATIVE CHEMOTAXIS 4 39 0.0009112 0.004344
976 GLANDULAR EPITHELIAL CELL DIFFERENTIATION 4 39 0.0009112 0.004344
977 NEGATIVE REGULATION OF CELL ADHESION 9 223 0.0009242 0.004401
978 CELL ACTIVATION INVOLVED IN IMMUNE RESPONSE 7 139 0.0009591 0.004563
979 REGULATION OF MITOCHONDRIAL DEPOLARIZATION 3 18 0.0009861 0.004663
980 POSITIVE REGULATION OF SYNAPTIC TRANSMISSION GLUTAMATERGIC 3 18 0.0009861 0.004663
981 ORGAN MATURATION 3 18 0.0009861 0.004663
982 RESPONSE TO CAFFEINE 3 18 0.0009861 0.004663
983 NOTOCHORD DEVELOPMENT 3 18 0.0009861 0.004663
984 MUSCLE CELL MIGRATION 3 18 0.0009861 0.004663
985 REGULATION OF IMMUNE EFFECTOR PROCESS 13 424 0.0009943 0.004692
986 RENAL SYSTEM PROCESS 6 102 0.0009934 0.004692
987 REGULATION OF CELL CYCLE PHASE TRANSITION 11 321 0.0009984 0.004707
988 MAMMARY GLAND MORPHOGENESIS 4 40 0.001004 0.004722
989 ENDOCRINE PANCREAS DEVELOPMENT 4 40 0.001004 0.004722
990 REGULATION OF CIRCADIAN RHYTHM 6 103 0.001045 0.004912
991 REGULATION OF PROTEIN COMPLEX ASSEMBLY 12 375 0.001076 0.005051
992 REGULATION OF LIPID STORAGE 4 41 0.001103 0.00513
993 MULTICELLULAR ORGANISMAL MOVEMENT 4 41 0.001103 0.00513
994 REGULATION OF MEMBRANE DEPOLARIZATION 4 41 0.001103 0.00513
995 ANION HOMEOSTASIS 4 41 0.001103 0.00513
996 CELLULAR RESPONSE TO ESTROGEN STIMULUS 4 41 0.001103 0.00513
997 MUSCULOSKELETAL MOVEMENT 4 41 0.001103 0.00513
998 MONOCYTE CHEMOTAXIS 4 41 0.001103 0.00513
999 CELLULAR RESPONSE TO REACTIVE OXYGEN SPECIES 6 104 0.001099 0.00513
1000 LACTATION 4 41 0.001103 0.00513
1001 POSITIVE REGULATION OF CARDIAC MUSCLE CELL PROLIFERATION 3 19 0.001161 0.005383
1002 CARTILAGE DEVELOPMENT INVOLVED IN ENDOCHONDRAL BONE MORPHOGENESIS 3 19 0.001161 0.005383
1003 MACROPHAGE DIFFERENTIATION 3 19 0.001161 0.005383
1004 POSITIVE REGULATION OF PROTEIN EXPORT FROM NUCLEUS 3 19 0.001161 0.005383
1005 CELLULAR CARBOHYDRATE METABOLIC PROCESS 7 144 0.001179 0.005452
1006 REGULATION OF RESPONSE TO CYTOKINE STIMULUS 7 144 0.001179 0.005452
1007 REGULATION OF ENDOTHELIAL CELL APOPTOTIC PROCESS 4 42 0.001208 0.005571
1008 REGULATION OF BONE REMODELING 4 42 0.001208 0.005571
1009 REGULATION OF HEART GROWTH 4 42 0.001208 0.005571
1010 PROTEIN OLIGOMERIZATION 13 434 0.001227 0.005653
1011 IMMUNE RESPONSE 24 1100 0.001314 0.006049
1012 REGULATION OF GLYCOPROTEIN METABOLIC PROCESS 4 43 0.00132 0.006065
1013 MYELOID LEUKOCYTE MEDIATED IMMUNITY 4 43 0.00132 0.006065
1014 PANCREAS DEVELOPMENT 5 73 0.001337 0.006136
1015 REGULATION OF SMOOTH MUSCLE CELL DIFFERENTIATION 3 20 0.001355 0.006176
1016 HYPEROSMOTIC RESPONSE 3 20 0.001355 0.006176
1017 NEGATIVE REGULATION OF CELL CYCLE ARREST 3 20 0.001355 0.006176
1018 GENETIC IMPRINTING 3 20 0.001355 0.006176
1019 RESPONSE TO MUSCLE ACTIVITY 3 20 0.001355 0.006176
1020 REGULATION OF TYROSINE PHOSPHORYLATION OF STAT5 PROTEIN 3 20 0.001355 0.006176
1021 LYMPH VESSEL DEVELOPMENT 3 20 0.001355 0.006176
1022 MALE SEX DIFFERENTIATION 7 148 0.001381 0.006288
1023 REGULATION OF CYTOKINE SECRETION 7 149 0.001436 0.006531
1024 REGULATION OF PROTEIN SECRETION 12 389 0.001468 0.00667
1025 DEVELOPMENTAL MATURATION 8 193 0.001491 0.006767
1026 GRANULOCYTE MIGRATION 5 75 0.001509 0.006838
1027 ODONTOGENESIS OF DENTIN CONTAINING TOOTH 5 75 0.001509 0.006838
1028 SUBSTANTIA NIGRA DEVELOPMENT 4 45 0.001567 0.007084
1029 POSITIVE REGULATION OF EXCITATORY POSTSYNAPTIC POTENTIAL 3 21 0.001568 0.007084
1030 RUFFLE ORGANIZATION 3 21 0.001568 0.007084
1031 EXTRACELLULAR MATRIX DISASSEMBLY 5 76 0.001601 0.007226
1032 ACTIN FILAMENT BASED PROCESS 13 450 0.001693 0.007628
1033 REGULATION OF MEMBRANE POTENTIAL 11 343 0.001693 0.007628
1034 INTRASPECIES INTERACTION BETWEEN ORGANISMS 4 46 0.001701 0.007633
1035 REGULATION OF ALPHA BETA T CELL DIFFERENTIATION 4 46 0.001701 0.007633
1036 SOCIAL BEHAVIOR 4 46 0.001701 0.007633
1037 REGULATION OF ACTIN FILAMENT BUNDLE ASSEMBLY 5 77 0.001697 0.007633
1038 POSITIVE REGULATION OF ENDOCYTOSIS 6 114 0.001762 0.0079
1039 REGULATION OF MITOCHONDRIAL MEMBRANE PERMEABILITY INVOLVED IN APOPTOTIC PROCESS 3 22 0.001801 0.008019
1040 LYMPHOCYTE COSTIMULATION 5 78 0.001797 0.008019
1041 POSITIVE REGULATION OF TRANSLATIONAL INITIATION 3 22 0.001801 0.008019
1042 REGULATION OF RECEPTOR MEDIATED ENDOCYTOSIS 5 78 0.001797 0.008019
1043 POSITIVE REGULATION OF MUSCLE HYPERTROPHY 3 22 0.001801 0.008019
1044 POSITIVE REGULATION OF CARDIAC MUSCLE HYPERTROPHY 3 22 0.001801 0.008019
1045 CELLULAR RESPONSE TO INTERLEUKIN 6 3 22 0.001801 0.008019
1046 NEGATIVE REGULATION OF EPITHELIAL CELL PROLIFERATION 6 115 0.001842 0.008177
1047 THYMUS DEVELOPMENT 4 47 0.001843 0.008177
1048 POSITIVE REGULATION OF DEPHOSPHORYLATION 4 47 0.001843 0.008177
1049 POSITIVE REGULATION OF GLIOGENESIS 4 47 0.001843 0.008177
1050 PROTEIN LOCALIZATION TO NUCLEUS 7 156 0.001867 0.008274
1051 RESPONSE TO VIRUS 9 247 0.001875 0.008302
1052 REGULATION OF SYNAPSE ASSEMBLY 5 79 0.001901 0.00841
1053 SKELETAL SYSTEM MORPHOGENESIS 8 201 0.001925 0.008505
1054 MONOSACCHARIDE METABOLIC PROCESS 8 202 0.001985 0.008764
1055 REGULATION OF CARDIAC MUSCLE TISSUE DEVELOPMENT 4 48 0.001994 0.008768
1056 RESPONSE TO AXON INJURY 4 48 0.001994 0.008768
1057 DIGESTIVE TRACT MORPHOGENESIS 4 48 0.001994 0.008768
1058 POSITIVE REGULATION OF WOUND HEALING 4 48 0.001994 0.008768
1059 POLYSACCHARIDE METABOLIC PROCESS 5 80 0.00201 0.008801
1060 HORMONE MEDIATED SIGNALING PATHWAY 7 158 0.002007 0.008801
1061 POSITIVE REGULATION OF LYMPHOCYTE DIFFERENTIATION 5 80 0.00201 0.008801
1062 CELLULAR RESPONSE TO STARVATION 6 117 0.002011 0.008801
1063 RESPONSE TO PURINE CONTAINING COMPOUND 7 158 0.002007 0.008801
1064 WNT SIGNALING PATHWAY 11 351 0.002028 0.008869
1065 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL METABOLIC PROCESS 3 23 0.002054 0.008924
1066 RESPONSE TO MAGNESIUM ION 3 23 0.002054 0.008924
1067 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE III PROMOTER 3 23 0.002054 0.008924
1068 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER IN RESPONSE TO STRESS 3 23 0.002054 0.008924
1069 REGULATION OF OSTEOBLAST PROLIFERATION 3 23 0.002054 0.008924
1070 TRABECULA FORMATION 3 23 0.002054 0.008924
1071 POSITIVE REGULATION OF COLLAGEN METABOLIC PROCESS 3 23 0.002054 0.008924
1072 REGULATION OF NEURONAL SYNAPTIC PLASTICITY 4 49 0.002152 0.009306
1073 REGULATION OF NITRIC OXIDE SYNTHASE ACTIVITY 4 49 0.002152 0.009306
1074 POSITIVE REGULATION OF CHEMOKINE PRODUCTION 4 49 0.002152 0.009306
1075 REGULATION OF STEROID BIOSYNTHETIC PROCESS 4 49 0.002152 0.009306
1076 CARDIAC CELL DEVELOPMENT 4 49 0.002152 0.009306
1077 JNK CASCADE 5 82 0.002241 0.009672
1078 REGULATION OF TRANSLATIONAL INITIATION 5 82 0.002241 0.009672
1079 NEGATIVE REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 3 24 0.002328 0.009986
1080 REGULATION OF MYELOID CELL APOPTOTIC PROCESS 3 24 0.002328 0.009986
1081 POSITIVE REGULATION OF OSTEOCLAST DIFFERENTIATION 3 24 0.002328 0.009986
1082 POSITIVE REGULATION OF EPITHELIAL CELL APOPTOTIC PROCESS 3 24 0.002328 0.009986
1083 POSITIVE REGULATION OF RECEPTOR INTERNALIZATION 3 24 0.002328 0.009986
1084 REGULATION OF LONG TERM NEURONAL SYNAPTIC PLASTICITY 3 24 0.002328 0.009986
1085 POSITIVE REGULATION OF LAMELLIPODIUM ORGANIZATION 3 24 0.002328 0.009986
NumGOOverlapSizeP ValueAdj. P Value
1 KINASE ACTIVITY 64 842 1.101e-35 7.072e-33
2 RECEPTOR BINDING 81 1476 1.523e-35 7.072e-33
3 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 67 992 2.735e-34 8.469e-32
4 PROTEIN KINASE ACTIVITY 52 640 3.823e-30 8.878e-28
5 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 23 70 4.355e-28 8.091e-26
6 MOLECULAR FUNCTION REGULATOR 69 1353 7.049e-28 1.091e-25
7 PROTEIN TYROSINE KINASE ACTIVITY 30 176 5.569e-27 7.39e-25
8 GROWTH FACTOR BINDING 26 123 4.684e-26 5.44e-24
9 ENZYME BINDING 73 1737 1.985e-24 2.049e-22
10 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE ACTIVITY 20 64 4.733e-24 4.397e-22
11 PROTEIN COMPLEX BINDING 52 935 2.093e-22 1.625e-20
12 MACROMOLECULAR COMPLEX BINDING 63 1399 2.1e-22 1.625e-20
13 TRANSMEMBRANE RECEPTOR PROTEIN KINASE ACTIVITY 20 81 9.596e-22 6.858e-20
14 GROWTH FACTOR ACTIVITY 25 160 1.18e-21 7.827e-20
15 KINASE BINDING 39 606 5.487e-19 3.399e-17
16 PROTEIN PHOSPHATASE TYPE 2A REGULATOR ACTIVITY 12 21 7.377e-19 4.283e-17
17 X1 PHOSPHATIDYLINOSITOL 3 KINASE ACTIVITY 14 43 1.793e-17 9.359e-16
18 GROWTH FACTOR RECEPTOR BINDING 20 129 1.813e-17 9.359e-16
19 PLATELET DERIVED GROWTH FACTOR RECEPTOR BINDING 10 15 6.938e-17 3.392e-15
20 PHOSPHATIDYLINOSITOL KINASE ACTIVITY 14 51 2.734e-16 1.27e-14
21 ENZYME REGULATOR ACTIVITY 44 959 7.809e-16 3.455e-14
22 INTEGRIN BINDING 17 105 2.374e-15 1.002e-13
23 SIGNAL TRANSDUCER ACTIVITY 59 1731 3.175e-15 1.283e-13
24 COLLAGEN BINDING 14 65 1.124e-14 4.353e-13
25 PROTEIN PHOSPHATASE BINDING 17 120 2.374e-14 8.823e-13
26 CELL ADHESION MOLECULE BINDING 20 186 2.571e-14 9.185e-13
27 PLATELET DERIVED GROWTH FACTOR BINDING 8 11 3.378e-14 1.162e-12
28 RAS GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 21 228 1.249e-13 4.145e-12
29 KINASE REGULATOR ACTIVITY 19 186 2.976e-13 9.26e-12
30 PHOSPHATASE BINDING 18 162 2.99e-13 9.26e-12
31 PROTEIN DIMERIZATION ACTIVITY 43 1149 1.9e-12 5.694e-11
32 PROTEIN HETERODIMERIZATION ACTIVITY 26 468 1.761e-11 5.111e-10
33 HEPARIN BINDING 16 157 2.453e-11 6.905e-10
34 GUANYL NUCLEOTIDE EXCHANGE FACTOR ACTIVITY 21 303 3e-11 8.196e-10
35 RIBONUCLEOTIDE BINDING 54 1860 3.609e-11 9.579e-10
36 IDENTICAL PROTEIN BINDING 42 1209 3.864e-11 9.97e-10
37 EXTRACELLULAR MATRIX STRUCTURAL CONSTITUENT 12 76 4.545e-11 1.141e-09
38 ADENYL NUCLEOTIDE BINDING 47 1514 1.004e-10 2.454e-09
39 EXTRACELLULAR MATRIX BINDING 10 51 2.08e-10 4.955e-09
40 PHOSPHATASE REGULATOR ACTIVITY 12 87 2.334e-10 5.42e-09
41 FIBRONECTIN BINDING 8 28 5.405e-10 1.225e-08
42 PROTEIN SERINE THREONINE KINASE ACTIVITY 23 445 1.131e-09 2.502e-08
43 SULFUR COMPOUND BINDING 17 234 1.198e-09 2.589e-08
44 GLYCOSAMINOGLYCAN BINDING 16 205 1.322e-09 2.792e-08
45 CYTOKINE RECEPTOR BINDING 18 271 1.618e-09 3.341e-08
46 NEUROTROPHIN RECEPTOR BINDING 6 14 5.007e-09 1.011e-07
47 INSULIN LIKE GROWTH FACTOR RECEPTOR BINDING 6 15 8.268e-09 1.6e-07
48 PROTEIN DOMAIN SPECIFIC BINDING 26 624 8.212e-09 1.6e-07
49 CHEMOATTRACTANT ACTIVITY 7 27 1.432e-08 2.716e-07
50 INSULIN RECEPTOR SUBSTRATE BINDING 5 11 7.209e-08 1.339e-06
51 SIGNALING RECEPTOR ACTIVITY 39 1393 8.571e-08 1.561e-06
52 PROTEIN HOMODIMERIZATION ACTIVITY 26 722 1.509e-07 2.696e-06
53 CAMP RESPONSE ELEMENT BINDING 5 13 1.972e-07 3.456e-06
54 RECEPTOR ACTIVITY 42 1649 3.37e-07 5.797e-06
55 CYCLIN DEPENDENT PROTEIN SERINE THREONINE KINASE REGULATOR ACTIVITY 6 28 5.513e-07 9.312e-06
56 PHOSPHATIDYLINOSITOL 3 KINASE BINDING 6 30 8.529e-07 1.39e-05
57 LAMININ BINDING 6 30 8.529e-07 1.39e-05
58 CYTOKINE BINDING 9 92 8.831e-07 1.414e-05
59 PROTEIN BINDING INVOLVED IN CELL ADHESION 5 17 9.142e-07 1.439e-05
60 INSULIN RECEPTOR BINDING 6 32 1.278e-06 1.978e-05
61 PROTEASE BINDING 9 104 2.488e-06 3.789e-05
62 PROTEIN SERINE THREONINE TYROSINE KINASE ACTIVITY 6 39 4.31e-06 6.458e-05
63 FIBROBLAST GROWTH FACTOR BINDING 5 23 4.707e-06 6.941e-05
64 KINASE ACTIVATOR ACTIVITY 7 62 5.697e-06 8.27e-05
65 PROTEIN SERINE THREONINE PHOSPHATASE ACTIVITY 7 64 7.062e-06 0.0001009
66 UBIQUITIN LIKE PROTEIN LIGASE BINDING 13 264 8.917e-06 0.0001255
67 FIBROBLAST GROWTH FACTOR RECEPTOR BINDING 5 28 1.314e-05 0.0001795
68 PROTEIN PHOSPHATASE 2A BINDING 5 28 1.314e-05 0.0001795
69 HISTONE DEACETYLASE BINDING 8 105 2.322e-05 0.0003127
70 SODIUM CHANNEL REGULATOR ACTIVITY 5 32 2.596e-05 0.0003445
71 PROTEIN TYROSINE KINASE BINDING 6 54 2.968e-05 0.0003884
72 PEPTIDE HORMONE BINDING 5 36 4.687e-05 0.0006047
73 HISTONE KINASE ACTIVITY 4 19 5.113e-05 0.0006507
74 CHEMOKINE BINDING 4 21 7.758e-05 0.0009739
75 ENZYME ACTIVATOR ACTIVITY 16 471 8.259e-05 0.001023
76 VIRUS RECEPTOR ACTIVITY 6 70 0.0001299 0.001588
77 EPHRIN RECEPTOR BINDING 4 24 0.0001342 0.001619
78 RECEPTOR SIGNALING PROTEIN ACTIVITY 9 172 0.0001383 0.001648
79 PHOSPHOPROTEIN PHOSPHATASE ACTIVITY 9 178 0.0001791 0.002107
80 ION CHANNEL BINDING 7 111 0.0002481 0.002881
81 TAU PROTEIN BINDING 3 12 0.0002793 0.003127
82 PHOSPHATASE ACTIVITY 11 275 0.0002758 0.003127
83 TRANSCRIPTION FACTOR BINDING 16 524 0.0002778 0.003127
84 PDZ DOMAIN BINDING 6 90 0.000513 0.005673
85 CHANNEL REGULATOR ACTIVITY 7 131 0.0006761 0.007263
86 MHC CLASS II PROTEIN COMPLEX BINDING 3 16 0.000688 0.007263
87 PROTEIN KINASE C ACTIVITY 3 16 0.000688 0.007263
88 PHOSPHATIDYLINOSITOL PHOSPHATE KINASE ACTIVITY 3 16 0.000688 0.007263
89 HORMONE BINDING 5 65 0.0007902 0.008248
90 CORECEPTOR ACTIVITY 4 38 0.0008249 0.008515
91 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 11 315 0.0008567 0.008746
NumGOOverlapSizeP ValueAdj. P Value
1 PROTEIN COMPLEX INVOLVED IN CELL ADHESION 16 30 4.195e-24 2.45e-21
2 EXTRACELLULAR MATRIX COMPONENT 24 125 4.663e-23 1.362e-20
3 EXTRACELLULAR MATRIX 36 426 1.913e-21 3.724e-19
4 RECEPTOR COMPLEX 32 327 4.7e-21 6.862e-19
5 BASEMENT MEMBRANE 20 93 1.935e-20 2.26e-18
6 PROTEINACEOUS EXTRACELLULAR MATRIX 32 356 6.186e-20 6.021e-18
7 PROTEIN PHOSPHATASE TYPE 2A COMPLEX 12 20 3.193e-19 2.664e-17
8 CELL SURFACE 43 757 7.46e-19 5.445e-17
9 PLASMA MEMBRANE RECEPTOR COMPLEX 23 175 2.921e-18 1.895e-16
10 CELL SUBSTRATE JUNCTION 31 398 1.527e-17 8.919e-16
11 TRANSFERASE COMPLEX TRANSFERRING PHOSPHORUS CONTAINING GROUPS 23 237 2.579e-15 1.351e-13
12 CATALYTIC COMPLEX 45 1038 2.777e-15 1.351e-13
13 ANCHORING JUNCTION 31 489 4.78e-15 2.147e-13
14 SIDE OF MEMBRANE 29 428 7.079e-15 2.953e-13
15 BASAL LAMINA 10 21 7.687e-15 2.993e-13
16 EXTRINSIC COMPONENT OF MEMBRANE 23 252 9.787e-15 3.572e-13
17 PLASMA MEMBRANE PROTEIN COMPLEX 31 510 1.501e-14 5.156e-13
18 COMPLEX OF COLLAGEN TRIMERS 10 23 2.445e-14 7.933e-13
19 INTRACELLULAR VESICLE 48 1259 3.705e-14 1.139e-12
20 PHOSPHATASE COMPLEX 12 48 1.342e-13 3.92e-12
21 MEMBRANE PROTEIN COMPLEX 42 1020 1.559e-13 4.335e-12
22 PHOSPHATIDYLINOSITOL 3 KINASE COMPLEX 9 20 3.421e-13 9.082e-12
23 CELL JUNCTION 42 1151 8.124e-12 2.063e-10
24 PROTEIN KINASE COMPLEX 13 90 2.236e-11 5.44e-10
25 PLATELET ALPHA GRANULE 12 75 3.865e-11 9.029e-10
26 INTRINSIC COMPONENT OF PLASMA MEMBRANE 50 1649 5.06e-11 1.137e-09
27 MEMBRANE REGION 40 1134 7.759e-11 1.678e-09
28 CYTOPLASMIC SIDE OF MEMBRANE 16 170 8.206e-11 1.712e-09
29 PERINUCLEAR REGION OF CYTOPLASM 29 642 1.608e-10 3.237e-09
30 VESICLE LUMEN 13 106 1.851e-10 3.603e-09
31 PLASMA MEMBRANE REGION 35 929 2.466e-10 4.645e-09
32 COLLAGEN TRIMER 12 88 2.676e-10 4.883e-09
33 PLATELET ALPHA GRANULE LUMEN 10 55 4.58e-10 8.105e-09
34 EXTRINSIC COMPONENT OF CYTOPLASMIC SIDE OF PLASMA MEMBRANE 12 98 9.597e-10 1.649e-08
35 EXTRACELLULAR SPACE 42 1376 2.014e-09 3.361e-08
36 EXTRINSIC COMPONENT OF PLASMA MEMBRANE 13 136 4.193e-09 6.803e-08
37 ENDOPLASMIC RETICULUM LUMEN 15 201 8.106e-09 1.279e-07
38 SECRETORY GRANULE LUMEN 10 85 3.661e-08 5.627e-07
39 CYCLIN DEPENDENT PROTEIN KINASE HOLOENZYME COMPLEX 7 31 4.084e-08 6.116e-07
40 HETEROTRIMERIC G PROTEIN COMPLEX 7 32 5.178e-08 7.56e-07
41 RUFFLE MEMBRANE 9 80 2.646e-07 3.769e-06
42 LEADING EDGE MEMBRANE 11 134 3.201e-07 4.451e-06
43 TRANSFERASE COMPLEX 25 703 3.367e-07 4.573e-06
44 CELL PROJECTION 44 1786 4.205e-07 5.581e-06
45 SECRETORY GRANULE 17 352 4.766e-07 6.185e-06
46 EXTERNAL SIDE OF PLASMA MEMBRANE 14 238 4.913e-07 6.237e-06
47 ENDOPLASMIC RETICULUM 41 1631 6.731e-07 8.364e-06
48 CYTOPLASMIC VESICLE PART 22 601 1.11e-06 1.351e-05
49 CELL PROJECTION MEMBRANE 15 298 1.373e-06 1.637e-05
50 CELL LEADING EDGE 16 350 2.138e-06 2.497e-05
51 VACUOLE 32 1180 2.857e-06 3.272e-05
52 SECRETORY VESICLE 18 461 4.539e-06 5.097e-05
53 MEMBRANE MICRODOMAIN 14 288 4.655e-06 5.129e-05
54 BANDED COLLAGEN FIBRIL 4 12 6.943e-06 7.509e-05
55 RUFFLE 10 156 1.031e-05 0.0001094
56 NEURON PART 32 1265 1.191e-05 0.0001242
57 PIGMENT GRANULE 8 103 2.019e-05 0.0002068
58 BASAL PART OF CELL 6 51 2.128e-05 0.0002143
59 BASOLATERAL PLASMA MEMBRANE 11 211 2.613e-05 0.0002587
60 NEURON PROJECTION 25 942 5.445e-05 0.00053
61 ENDOPLASMIC RETICULUM PART 28 1163 0.0001035 0.0009907
62 LAMELLIPODIUM 9 172 0.0001383 0.001303
63 ENDOSOME 21 793 0.0002273 0.002107
64 SOMATODENDRITIC COMPARTMENT 18 650 0.0003797 0.003465
65 CELL PROJECTION PART 23 946 0.0003873 0.00348
66 BASAL PLASMA MEMBRANE 4 33 0.0004776 0.004226
67 SYNAPSE 19 754 0.0008242 0.007184
68 FILOPODIUM MEMBRANE 3 18 0.0009861 0.008469
69 LAMELLIPODIUM MEMBRANE 3 19 0.001161 0.00983

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 hsa04151_PI3K_AKT_signaling_pathway 223 351 0 0
2 hsa04510_Focal_adhesion 84 200 5.015e-115 4.514e-113
3 hsa04014_Ras_signaling_pathway 77 236 1.503e-94 9.016e-93
4 hsa04512_ECM.receptor_interaction 45 85 2.432e-66 1.094e-64
5 hsa04810_Regulation_of_actin_cytoskeleton 53 214 7.007e-57 2.523e-55
6 hsa04910_Insulin_signaling_pathway 36 138 1.986e-39 5.957e-38
7 hsa04722_Neurotrophin_signaling_pathway 34 127 1.095e-37 2.816e-36
8 hsa04150_mTOR_signaling_pathway 26 52 1.463e-37 3.292e-36
9 hsa04010_MAPK_signaling_pathway 40 268 1.9e-33 3.801e-32
10 hsa04012_ErbB_signaling_pathway 27 87 4.901e-32 8.822e-31
11 hsa04062_Chemokine_signaling_pathway 32 189 1.227e-28 2.008e-27
12 hsa04662_B_cell_receptor_signaling_pathway 23 75 2.756e-27 4.133e-26
13 hsa04630_Jak.STAT_signaling_pathway 25 155 5.23e-22 7.242e-21
14 hsa04370_VEGF_signaling_pathway 19 76 7.952e-21 1.022e-19
15 hsa04664_Fc_epsilon_RI_signaling_pathway 19 79 1.785e-20 2.141e-19
16 hsa04660_T_cell_receptor_signaling_pathway 21 108 1.987e-20 2.236e-19
17 hsa04380_Osteoclast_differentiation 21 128 8.186e-19 8.667e-18
18 hsa04620_Toll.like_receptor_signaling_pathway 19 102 3.231e-18 3.231e-17
19 hsa04960_Aldosterone.regulated_sodium_reabsorption 14 42 1.221e-17 1.157e-16
20 hsa04210_Apoptosis 17 89 1.284e-16 1.155e-15
21 hsa04110_Cell_cycle 19 128 2.747e-16 2.355e-15
22 hsa04650_Natural_killer_cell_mediated_cytotoxicity 19 136 8.768e-16 7.174e-15
23 hsa04540_Gap_junction 16 90 3.439e-15 2.692e-14
24 hsa04114_Oocyte_meiosis 17 114 9.857e-15 7.393e-14
25 hsa04115_p53_signaling_pathway 14 69 2.741e-14 1.973e-13
26 hsa04914_Progesterone.mediated_oocyte_maturation 15 87 4.13e-14 2.859e-13
27 hsa04390_Hippo_signaling_pathway 18 154 1.233e-13 8.217e-13
28 hsa04666_Fc_gamma_R.mediated_phagocytosis 15 95 1.601e-13 1.029e-12
29 hsa04640_Hematopoietic_cell_lineage 14 88 9.463e-13 5.874e-12
30 hsa03015_mRNA_surveillance_pathway 13 83 7.707e-12 4.624e-11
31 hsa04920_Adipocytokine_signaling_pathway 12 68 1.154e-11 6.699e-11
32 hsa04530_Tight_junction 15 133 2.426e-11 1.365e-10
33 hsa04973_Carbohydrate_digestion_and_absorption 10 44 4.324e-11 2.358e-10
34 hsa04916_Melanogenesis 13 101 9.967e-11 5.277e-10
35 hsa04310_Wnt_signaling_pathway 15 151 1.51e-10 7.765e-10
36 hsa04730_Long.term_depression 11 70 3.144e-10 1.572e-09
37 hsa04360_Axon_guidance 13 130 2.405e-09 1.17e-08
38 hsa04350_TGF.beta_signaling_pathway 11 85 2.678e-09 1.268e-08
39 hsa04670_Leukocyte_transendothelial_migration 12 117 7.52e-09 3.471e-08
40 hsa04974_Protein_digestion_and_absorption 10 81 2.285e-08 1.028e-07
41 hsa04144_Endocytosis 14 203 6.971e-08 3.06e-07
42 hsa04145_Phagosome 12 156 1.884e-07 8.073e-07
43 hsa04070_Phosphatidylinositol_signaling_system 9 78 2.121e-07 8.88e-07
44 hsa04912_GnRH_signaling_pathway 9 101 1.946e-06 7.963e-06
45 hsa04320_Dorso.ventral_axis_formation 5 25 7.298e-06 2.919e-05
46 hsa04621_NOD.like_receptor_signaling_pathway 6 59 4.944e-05 0.0001934
47 hsa04962_Vasopressin.regulated_water_reabsorption 5 44 0.0001256 0.0004809
48 hsa04720_Long.term_potentiation 6 70 0.0001299 0.0004872
49 hsa04520_Adherens_junction 6 73 0.0001641 0.0006027
50 hsa04514_Cell_adhesion_molecules_.CAMs. 7 136 0.0008438 0.003038
51 hsa04623_Cytosolic_DNA.sensing_pathway 4 56 0.003511 0.01239
52 hsa00562_Inositol_phosphate_metabolism 4 57 0.003744 0.01296
53 hsa03320_PPAR_signaling_pathway 4 70 0.007769 0.02639
54 hsa00500_Starch_and_sucrose_metabolism 3 54 0.02236 0.07454
55 hsa04964_Proximal_tubule_bicarbonate_reclamation 2 23 0.02685 0.08787
56 hsa00010_Glycolysis_._Gluconeogenesis 3 65 0.03605 0.1159
57 hsa00020_Citrate_cycle_.TCA_cycle. 2 30 0.04388 0.1386
58 hsa04622_RIG.I.like_receptor_signaling_pathway 3 71 0.04496 0.1395
59 hsa04020_Calcium_signaling_pathway 5 177 0.04851 0.148
60 hsa04140_Regulation_of_autophagy 2 34 0.05499 0.165
61 hsa04612_Antigen_processing_and_presentation 3 78 0.0566 0.167
62 hsa00620_Pyruvate_metabolism 2 40 0.07324 0.2126
63 hsa03013_RNA_transport 4 152 0.09057 0.2588
64 hsa04672_Intestinal_immune_network_for_IgA_production 2 49 0.1036 0.2913
65 hsa04270_Vascular_smooth_muscle_contraction 3 116 0.14 0.3876
66 hsa04610_Complement_and_coagulation_cascades 2 69 0.1796 0.4899
67 hsa04141_Protein_processing_in_endoplasmic_reticulum 3 168 0.2887 0.7531
68 hsa04972_Pancreatic_secretion 2 101 0.3109 0.7994
69 hsa04120_Ubiquitin_mediated_proteolysis 2 139 0.4604 1

lncRNA-mediated sponge

(Download full result)

Num lncRNA miRNAs           miRNAs count     Gene Sponge regulatory network lncRNA log2FC lncRNA pvalue Gene log2FC Gene pvalue lncRNA-gene Pearson correlation
1

HCG11

hsa-miR-107;hsa-miR-130b-3p;hsa-miR-130b-5p;hsa-miR-148a-5p;hsa-miR-151a-5p;hsa-miR-17-3p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-421;hsa-miR-618 10 NTRK2 Sponge network -0.781 0 -2.305 0 0.582
2

HCG11

hsa-miR-106b-5p;hsa-miR-107;hsa-miR-15a-5p;hsa-miR-17-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-33a-3p;hsa-miR-362-3p;hsa-miR-502-3p;hsa-miR-93-5p 10 AKT3 Sponge network -0.781 0 -0.659 0.00047 0.574
3 DHRS4-AS1 hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-582-5p;hsa-miR-589-3p 10 PIK3R1 Sponge network -0.646 0.01829 -0.892 0 0.557
4

LINC00261

hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-188-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-324-3p;hsa-miR-330-3p;hsa-miR-629-3p 11 PIK3R1 Sponge network -1.194 0 -0.892 0 0.513
5 CTC-444N24.11 hsa-miR-122-5p;hsa-miR-139-5p;hsa-miR-193b-3p;hsa-miR-195-5p;hsa-miR-22-3p;hsa-miR-29a-3p;hsa-miR-29c-3p;hsa-miR-33a-3p;hsa-miR-424-5p;hsa-miR-497-5p 10 LAMC1 Sponge network 1.087 0 1.182 0 0.49
6

RP11-12A2.3

hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-188-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -4.779 0 -0.892 0 0.489
7 LINC01018 hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-324-3p;hsa-miR-338-5p;hsa-miR-589-3p;hsa-miR-629-3p;hsa-miR-93-5p 15 PIK3R1 Sponge network -3.231 0 -0.892 0 0.472
8

LINC00665

hsa-miR-122-5p;hsa-miR-139-5p;hsa-miR-193b-3p;hsa-miR-195-5p;hsa-miR-22-3p;hsa-miR-29a-3p;hsa-miR-29c-3p;hsa-miR-33a-3p;hsa-miR-424-5p;hsa-miR-497-5p 10 LAMC1 Sponge network 2.394 0 1.182 0 0.469
9 LDLRAD4-AS1 hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-93-5p 10 PIK3R1 Sponge network -3.366 0 -0.892 0 0.45
10 RP11-43F13.3 hsa-miR-122-5p;hsa-miR-1269a;hsa-miR-140-3p;hsa-miR-148a-5p;hsa-miR-15a-5p;hsa-miR-192-5p;hsa-miR-194-3p;hsa-miR-194-5p;hsa-miR-204-5p;hsa-miR-365a-3p;hsa-miR-500a-3p 11 IGF1R Sponge network -1.507 0.01021 -0.705 0.00354 0.423
11

SNHG1

hsa-miR-122-5p;hsa-miR-139-5p;hsa-miR-193b-3p;hsa-miR-195-5p;hsa-miR-22-3p;hsa-miR-29a-3p;hsa-miR-29c-3p;hsa-miR-33a-3p;hsa-miR-424-5p;hsa-miR-497-5p 10 LAMC1 Sponge network 2.013 0 1.182 0 0.42
12 RP11-119D9.1 hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-188-5p;hsa-miR-200c-3p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-629-3p;hsa-miR-93-5p 11 PIK3R1 Sponge network -2.765 0 -0.892 0 0.418
13

HCG18

hsa-miR-122-5p;hsa-miR-139-5p;hsa-miR-193b-3p;hsa-miR-195-5p;hsa-miR-22-3p;hsa-miR-29a-3p;hsa-miR-29c-3p;hsa-miR-33a-3p;hsa-miR-424-5p;hsa-miR-497-5p 10 LAMC1 Sponge network 1.42 0 1.182 0 0.417
14 FAM225B hsa-miR-122-5p;hsa-miR-148a-5p;hsa-miR-192-5p;hsa-miR-194-3p;hsa-miR-194-5p;hsa-miR-204-5p;hsa-miR-33a-3p;hsa-miR-378a-3p;hsa-miR-378a-5p;hsa-miR-378c;hsa-miR-455-5p 11 IGF1R Sponge network 0.684 0.04717 -0.705 0.00354 0.406
15

RP11-175O19.4

hsa-miR-193b-3p;hsa-miR-195-3p;hsa-miR-22-3p;hsa-miR-28-5p;hsa-miR-30c-5p;hsa-miR-30e-5p;hsa-miR-328-3p;hsa-miR-378a-3p;hsa-miR-455-3p;hsa-miR-505-5p 10 YWHAZ Sponge network 0.743 0 0.521 0 0.405
16 RP11-563J2.2 hsa-miR-122-5p;hsa-miR-140-3p;hsa-miR-148a-5p;hsa-miR-192-5p;hsa-miR-194-3p;hsa-miR-194-5p;hsa-miR-204-5p;hsa-miR-33a-3p;hsa-miR-378a-3p;hsa-miR-378c 10 IGF1R Sponge network -0.257 0.57019 -0.705 0.00354 0.402
17 RP11-290F5.1 hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-324-3p 11 PIK3R1 Sponge network -1.679 5.0E-5 -0.892 0 0.402
18 CTD-2015G9.2 hsa-miR-122-5p;hsa-miR-148a-5p;hsa-miR-192-5p;hsa-miR-194-3p;hsa-miR-194-5p;hsa-miR-204-5p;hsa-miR-33a-3p;hsa-miR-362-3p;hsa-miR-378a-3p;hsa-miR-378c;hsa-miR-616-5p;hsa-miR-99a-5p 12 IGF1R Sponge network 1.826 0.00897 -0.705 0.00354 0.389
19

LINC00152

hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-195-5p;hsa-miR-26b-5p;hsa-miR-27b-3p;hsa-miR-30c-5p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-3607-3p;hsa-miR-497-5p 10 ITGA2 Sponge network 2.553 0 1.531 0 0.382
20

RP5-1120P11.1

hsa-miR-122-5p;hsa-miR-139-5p;hsa-miR-193b-3p;hsa-miR-195-5p;hsa-miR-22-3p;hsa-miR-29a-3p;hsa-miR-29c-3p;hsa-miR-33a-3p;hsa-miR-424-5p;hsa-miR-497-5p 10 LAMC1 Sponge network 3.942 0 1.182 0 0.382
21 RP11-747H7.3 hsa-miR-122-5p;hsa-miR-1269a;hsa-miR-148a-5p;hsa-miR-192-5p;hsa-miR-194-3p;hsa-miR-194-5p;hsa-miR-204-5p;hsa-miR-33a-3p;hsa-miR-34a-5p;hsa-miR-374a-5p;hsa-miR-378a-3p;hsa-miR-378a-5p;hsa-miR-378c;hsa-miR-616-5p 14 IGF1R Sponge network 0.351 0.40524 -0.705 0.00354 0.38
22 ALDH1L1-AS2 hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-125a-5p;hsa-miR-141-3p;hsa-miR-141-5p;hsa-miR-182-5p;hsa-miR-200a-3p;hsa-miR-21-5p;hsa-miR-23a-3p;hsa-miR-301a-3p 10 IL6R Sponge network 0.116 0.79006 -0.197 0.38255 0.373
23 LINC00883 hsa-miR-122-5p;hsa-miR-148a-5p;hsa-miR-192-5p;hsa-miR-193a-5p;hsa-miR-194-3p;hsa-miR-194-5p;hsa-miR-33a-3p;hsa-miR-365a-3p;hsa-miR-378a-3p;hsa-miR-378c 10 IGF1R Sponge network 0.72 0.01612 -0.705 0.00354 0.371
24

LINC00238

hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-188-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-629-3p 12 PIK3R1 Sponge network -4.997 0 -0.892 0 0.369
25

HCG18

hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-195-5p;hsa-miR-26b-5p;hsa-miR-27b-3p;hsa-miR-30e-5p;hsa-miR-326;hsa-miR-33a-3p;hsa-miR-3607-3p;hsa-miR-497-5p 10 ITGA2 Sponge network 1.42 0 1.531 0 0.369
26

LINC00261

hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-140-3p;hsa-miR-15b-3p;hsa-miR-15b-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-181c-5p;hsa-miR-21-5p;hsa-miR-27a-3p;hsa-miR-330-3p;hsa-miR-330-5p;hsa-miR-501-5p 13 INSR Sponge network -1.194 0 -0.278 0.00786 0.366
27 MAGI2-AS3 hsa-miR-106b-5p;hsa-miR-1266-5p;hsa-miR-15b-5p;hsa-miR-17-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-589-3p;hsa-miR-616-5p;hsa-miR-9-5p;hsa-miR-92a-3p;hsa-miR-93-5p 13 CCND1 Sponge network -1.801 0 -0.902 1.0E-5 0.359
28

AC004862.6

hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-188-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-629-3p;hsa-miR-93-5p 12 PIK3R1 Sponge network -2.202 0.00081 -0.892 0 0.357
29 PART1 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-26a-5p;hsa-miR-30e-3p 10 PRKAA2 Sponge network 3.525 1.0E-5 0.91 0.01333 0.351
30 RP11-407B7.1 hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-324-3p;hsa-miR-338-5p;hsa-miR-629-3p;hsa-miR-93-5p 10 PIK3R1 Sponge network -0.818 0.00584 -0.892 0 0.324
31

SNHG12

hsa-miR-122-5p;hsa-miR-139-5p;hsa-miR-193b-3p;hsa-miR-195-5p;hsa-miR-22-3p;hsa-miR-29a-3p;hsa-miR-29c-3p;hsa-miR-33a-3p;hsa-miR-424-5p;hsa-miR-497-5p 10 LAMC1 Sponge network 1.791 0 1.182 0 0.323
32

RP11-166D19.1

hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-17-5p;hsa-miR-185-5p;hsa-miR-188-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-324-3p;hsa-miR-589-3p;hsa-miR-590-5p;hsa-miR-629-3p 11 PIK3R1 Sponge network -0.244 0.28835 -0.892 0 0.32
33

RP11-89K21.1

hsa-miR-122-5p;hsa-miR-139-5p;hsa-miR-193b-3p;hsa-miR-195-5p;hsa-miR-22-3p;hsa-miR-29a-3p;hsa-miR-29c-3p;hsa-miR-33a-3p;hsa-miR-424-5p;hsa-miR-497-5p 10 LAMC1 Sponge network 4.915 0 1.182 0 0.319
34 SNHG14 hsa-miR-122-5p;hsa-miR-148a-5p;hsa-miR-192-5p;hsa-miR-193a-5p;hsa-miR-194-3p;hsa-miR-194-5p;hsa-miR-378a-3p;hsa-miR-378a-5p;hsa-miR-378c;hsa-miR-455-5p;hsa-miR-885-5p 11 IGF1R Sponge network 0.608 0.02834 -0.705 0.00354 0.309
35 TOB1-AS1 hsa-miR-142-5p;hsa-miR-146a-5p;hsa-miR-150-5p;hsa-miR-181a-5p;hsa-miR-181b-5p;hsa-miR-181c-5p;hsa-miR-218-5p;hsa-miR-2355-3p;hsa-miR-330-3p;hsa-miR-450b-5p 10 PRKCA Sponge network 0.811 0 0.663 0 0.308
36 LINC00654 hsa-miR-122-5p;hsa-miR-148a-5p;hsa-miR-192-5p;hsa-miR-194-3p;hsa-miR-194-5p;hsa-miR-33a-3p;hsa-miR-378a-5p;hsa-miR-378c;hsa-miR-885-5p;hsa-miR-99a-5p 10 IGF1R Sponge network 0.697 0.02064 -0.705 0.00354 0.308
37 DLGAP1-AS2 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-26a-5p;hsa-miR-30e-3p 10 PRKAA2 Sponge network 1.357 0 0.91 0.01333 0.306
38 RP11-403I13.8 hsa-miR-122-5p;hsa-miR-148a-5p;hsa-miR-192-5p;hsa-miR-194-3p;hsa-miR-194-5p;hsa-miR-204-5p;hsa-miR-33a-3p;hsa-miR-365a-3p;hsa-miR-378a-3p;hsa-miR-378a-5p;hsa-miR-378c;hsa-miR-885-5p 12 IGF1R Sponge network 0.602 0.00406 -0.705 0.00354 0.297
39

ZFAS1

hsa-miR-122-5p;hsa-miR-139-5p;hsa-miR-193b-3p;hsa-miR-195-5p;hsa-miR-22-3p;hsa-miR-29a-3p;hsa-miR-29c-3p;hsa-miR-424-5p;hsa-miR-497-5p;hsa-miR-7-1-3p 10 LAMC1 Sponge network 1.155 0 1.182 0 0.295
40 GAS5 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p 11 PRKAA2 Sponge network 1.966 0 0.91 0.01333 0.294
41 MIAT hsa-miR-122-5p;hsa-miR-148a-5p;hsa-miR-192-5p;hsa-miR-193a-5p;hsa-miR-194-3p;hsa-miR-194-5p;hsa-miR-33a-3p;hsa-miR-378a-3p;hsa-miR-378a-5p;hsa-miR-378c;hsa-miR-455-5p 11 IGF1R Sponge network 1.039 0.0004 -0.705 0.00354 0.292
42

AC005562.1

hsa-let-7b-3p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p;hsa-miR-628-3p 11 PRKAA2 Sponge network 1.127 0 0.91 0.01333 0.29
43 AC016747.3 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p 10 PRKAA2 Sponge network 1.235 0 0.91 0.01333 0.29
44 RP4-717I23.3 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p;hsa-miR-628-3p 12 PRKAA2 Sponge network 1.867 0 0.91 0.01333 0.285
45 RP1-228H13.5 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p 11 PRKAA2 Sponge network 1.554 0 0.91 0.01333 0.285
46

RP11-166D19.1

hsa-miR-106b-5p;hsa-miR-130b-3p;hsa-miR-148b-3p;hsa-miR-15b-3p;hsa-miR-16-2-3p;hsa-miR-186-5p;hsa-miR-21-5p;hsa-miR-25-3p;hsa-miR-425-5p;hsa-miR-484;hsa-miR-589-3p;hsa-miR-590-5p 12 PTEN Sponge network -0.244 0.28835 -0.546 0 0.28
47 AP001469.9 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p 10 PRKAA2 Sponge network 2.428 0 0.91 0.01333 0.279
48 AC074117.10 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p 11 PRKAA2 Sponge network 1.254 0 0.91 0.01333 0.275
49 TPT1-AS1 hsa-miR-122-5p;hsa-miR-148a-5p;hsa-miR-192-5p;hsa-miR-193a-5p;hsa-miR-194-3p;hsa-miR-194-5p;hsa-miR-33a-3p;hsa-miR-378a-3p;hsa-miR-378a-5p;hsa-miR-378c;hsa-miR-455-5p 11 IGF1R Sponge network 0.45 2.0E-5 -0.705 0.00354 0.273
50 RP11-121C2.2 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p 11 PRKAA2 Sponge network 1.286 0 0.91 0.01333 0.273
51

RP11-166D19.1

hsa-miR-130b-3p;hsa-miR-151a-5p;hsa-miR-17-3p;hsa-miR-185-5p;hsa-miR-186-5p;hsa-miR-361-5p;hsa-miR-421;hsa-miR-532-5p;hsa-miR-590-5p;hsa-miR-618 10 NTRK2 Sponge network -0.244 0.28835 -2.305 0 0.271
52 RP11-7F17.3 hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-188-5p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-324-3p 11 PIK3R1 Sponge network -0.873 0.00204 -0.892 0 0.271
53

SMIM2-AS1

hsa-miR-103a-3p;hsa-miR-106b-5p;hsa-miR-1301-3p;hsa-miR-132-3p;hsa-miR-17-5p;hsa-miR-200c-3p;hsa-miR-20a-5p;hsa-miR-21-5p;hsa-miR-212-3p;hsa-miR-221-3p;hsa-miR-222-3p;hsa-miR-629-3p 12 PIK3R1 Sponge network -0.66 0.00587 -0.892 0 0.27
54

SMIM2-AS1

hsa-let-7e-5p;hsa-let-7i-5p;hsa-miR-125a-5p;hsa-miR-155-5p;hsa-miR-182-5p;hsa-miR-21-5p;hsa-miR-23a-3p;hsa-miR-301a-3p;hsa-miR-331-3p;hsa-miR-501-5p 10 IL6R Sponge network -0.66 0.00587 -0.197 0.38255 0.261
55 TMCC1-AS1 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p 10 PRKAA2 Sponge network 2.298 0 0.91 0.01333 0.258
56

RP11-166D19.1

hsa-miR-106a-5p;hsa-miR-106b-5p;hsa-miR-1266-5p;hsa-miR-15b-5p;hsa-miR-16-5p;hsa-miR-17-5p;hsa-miR-186-5p;hsa-miR-19a-3p;hsa-miR-19b-1-5p;hsa-miR-19b-3p;hsa-miR-20a-5p;hsa-miR-425-5p;hsa-miR-589-3p;hsa-miR-616-5p;hsa-miR-92a-3p;hsa-miR-942-5p 16 CCND1 Sponge network -0.244 0.28835 -0.902 1.0E-5 0.253
57 KB-1460A1.5 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p 11 PRKAA2 Sponge network 1.949 0 0.91 0.01333 0.253
58 LINC00680 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-130a-3p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p 10 PRKAA2 Sponge network 1.404 0 0.91 0.01333 0.252
59 AC073283.4 hsa-let-7b-3p;hsa-let-7b-5p;hsa-let-7c-5p;hsa-miR-125b-5p;hsa-miR-139-5p;hsa-miR-144-3p;hsa-miR-195-3p;hsa-miR-22-5p;hsa-miR-26a-5p;hsa-miR-30e-3p 10 PRKAA2 Sponge network 1.514 0 0.91 0.01333 0.251

Quest ID: f48d1fd4a72d24afde8c9af5a31b69f7