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This regulatory network was inferred from the input dataset. The miRNAs and mRNAs are presented as round and rectangle nodes respectively. The numerical value popped up upon mouse over the gene node is the log2 transformed fold-change of the gene expression between the two groups. All of the nodes are clickable, and the detailed information of the miRNAs/mRNAs and related cancer pathway will be displayed in another window. The edges between nodes are supported by both interactions (predicted or experimentally verified) and correlations learnt from cancer dataset. The numerical value popped up upon mouse over the edge is the correlation beat value (effect size) between the two nodes. The experimental evidences of the edges reported in previous cancer studies are highlighted by red/orange color. All of these information can be accessed by the "mouse-over" action. This network shows a full map of the miRNA-mRNA regulation of the input gene list(s), and the hub miRNAs (with the high network degree/betweenness centrality) would be the potential cancer drivers or tumor suppressors. The full result table can be accessed in the "Regulations" tab.

"miRNACancerMAP" is also a network visualization tool for users to draw their regulatory network by personal customization. Users can set the complexity of the network by limiting the number of nodes or edges. And the color of the nodes can be defined by different categories of the mRNAs and miRNAs, such as Gene-Ontology, pathway, and expression status. Users can also select to use network degree or network betweenness centrality to define the node size. And edges can be black or colored by the correlation. Purple edge means negative correlation (mostly found between miRNA and mRNA), and blue edge means positive correlation (found in PPI or miRNA-miRNA sponge effect). We can also add the protein-protein interactions (PPI) into the network. This result will show the cluster of genes regulated by some specific miRNAs. Additionally, miRNA-miRNA edges can be added by the "miRNA sponge" button, presenting some clusters of miRNAs that have the interactions via sponge effect.

miRNA-gene regulations

(Download full result)

Num microRNA           Gene miRNA log2FC miRNA pvalue Gene log2FC Gene pvalue Interaction Correlation beta Correlation P-value PMID Reported in cancer studies
1 hsa-miR-342-3p AACS -0.2 3.0E-5 0.18 0.00035 miRanda -0.4 0.00057 NA
2 hsa-miR-188-5p AAK1 0.48 7.0E-5 -0.25 0.00754 PITA -0.28 0.00067 NA
3 hsa-miR-636 AAK1 0.37 0.00023 -0.25 0.00754 PITA -0.25 0.0157 NA
4 hsa-miR-342-3p AAMP -0.2 3.0E-5 0.12 0.01751 PITA; miRanda; miRNATAP -0.26 0.0309 NA
5 hsa-miR-139-5p AASDHPPT -0.96 0 0.3 0.00018 miRanda -0.11 0.04034 NA
6 hsa-miR-342-3p AASDHPPT -0.2 3.0E-5 0.3 0.00018 miRanda -0.47 0.01589 NA
7 hsa-miR-139-5p ABCA13 -0.96 0 0.16 0.01084 miRanda -0.11 0.00784 NA
8 hsa-miR-129-5p ABCA5 0.13 0.23985 -1.21 0 mirMAP -0.5 0.01622 NA
9 hsa-miR-342-3p ABCB10 -0.2 3.0E-5 0.08 0.04456 miRanda -0.27 0.00385 NA
10 hsa-miR-133b ABCC1 -0.56 0 0.49 1.0E-5 miRNATAP -0.21 0.04929 NA
11 hsa-miR-107 ABCC12 0.02 0.45295 0.08 0.17235 miRanda -0.62 0.03045 NA
12 hsa-miR-1283 ABHD13 -0.15 0.08004 -0.02 0.88905 mirMAP -0.42 0.00316 NA
13 hsa-miR-1253 ABHD17B 0 0.96973 -0.31 0.00061 MirTarget -0.43 0.00235 NA
14 hsa-miR-139-5p ABHD2 -0.96 0 0.62 1.0E-5 miRanda -0.2 0.04461 NA
15 hsa-miR-518d-5p ABHD2 -0.17 0.02136 0.62 1.0E-5 mirMAP -0.55 0.0185 NA
16 hsa-miR-607 ABI1 -0.07 0.34593 0.02 0.83355 mirMAP -0.29 0.02294 NA
17 hsa-miR-342-3p ABI2 -0.2 3.0E-5 0.25 0.00518 miRanda -0.53 0.01527 NA
18 hsa-miR-1275 ABL1 0.24 0.00451 -0.24 0.00022 MirTarget -0.26 0.00295 NA
19 hsa-miR-621 ABL2 -0.26 0.00457 0.2 0.00058 miRNATAP -0.15 0.03366 NA
20 hsa-miR-129-5p ABLIM1 0.13 0.23985 -0.26 0.00378 miRanda; mirMAP -0.25 0.0103 NA
21 hsa-miR-556-5p ABLIM1 0.21 0.0022 -0.26 0.00378 mirMAP -0.32 0.03105 NA
22 hsa-miR-875-3p ABLIM1 0.18 0.096 -0.26 0.00378 mirMAP -0.2 0.0312 NA
23 hsa-miR-1283 ACACA -0.15 0.08004 0.51 0 MirTarget; PITA; miRNATAP -0.28 0.03408 NA
24 hsa-miR-139-5p ACACA -0.96 0 0.51 0 miRanda -0.24 0.00015 NA
25 hsa-miR-654-5p ACACB 0.2 0.03487 -0.69 0 MirTarget -0.4 0.00304 NA
26 hsa-miR-133b ACAD9 -0.56 0 0.22 0.00043 miRanda -0.14 0.01482 NA
27 hsa-miR-1275 ACADS 0.24 0.00451 -0.45 0 MirTarget -0.22 0.04518 NA
28 hsa-miR-342-3p ACAN -0.2 3.0E-5 0.26 0 miRanda -0.31 0.02467 NA
29 hsa-miR-133b ACAT2 -0.56 0 -0.08 0.41551 MirTarget; miRanda; miRNATAP -0.18 0.04704 NA
30 hsa-miR-139-5p ACD -0.96 0 0.28 0 miRanda -0.11 0.00421 NA
31 hsa-miR-875-3p ACER3 0.18 0.096 -0.53 0 MirTarget -0.28 0.02029 NA
32 hsa-miR-139-5p ACLY -0.96 0 0.48 0 miRanda -0.16 0.02448 NA
33 hsa-miR-875-3p ACO1 0.18 0.096 -0.15 0.11163 MirTarget -0.24 0.01882 NA
34 hsa-miR-875-3p ACOT11 0.18 0.096 -0.25 0.00067 mirMAP -0.29 0.0001 NA
35 hsa-miR-636 ACOX1 0.37 0.00023 -0.69 0 mirMAP -0.38 0.00835 NA
36 hsa-miR-568 ACP2 0.08 0.30754 -0.11 0.04075 miRNATAP -0.17 0.0445 NA
37 hsa-miR-607 ACSL4 -0.07 0.34593 0.29 0.04133 mirMAP; miRNATAP -0.52 0.02099 NA
38 hsa-miR-875-3p ACSL5 0.18 0.096 -0.21 0.23881 PITA; miRNATAP -0.89 0 NA
39 hsa-miR-1297 ACSS1 0.02 0.75457 0.19 0.04709 miRanda -0.29 0.04611 NA
40 hsa-miR-107 ACTG1 0.02 0.45295 0.13 0.04338 miRanda; miRNATAP -0.69 0.04066 NA
41 hsa-miR-1224-5p ACTL6B 0.15 0.23912 0.02 0.71966 MirTarget -0.1 0.04303 NA
42 hsa-miR-324-3p ACTN4 -0.15 0.01636 0.08 0.26115 miRNAWalker2 validate; PITA; miRNATAP -0.25 0.04571 NA
43 hsa-miR-637 ACTR1A 0.19 0.15577 -0.12 0.05538 mirMAP -0.15 0.00387 NA
44 hsa-miR-342-3p ACTR3B -0.2 3.0E-5 0.28 0 miRanda -0.51 2.0E-5 NA
45 hsa-miR-188-5p ACVR2A 0.48 7.0E-5 -0.4 1.0E-5 PITA -0.25 0.00262 NA
46 hsa-miR-1275 ACVRL1 0.24 0.00451 -0.74 0 mirMAP -0.42 0.01148 NA
47 hsa-miR-133b ADAM12 -0.56 0 0.53 0.00013 miRanda -0.31 0.01966 NA
48 hsa-miR-139-5p ADAM12 -0.96 0 0.53 0.00013 miRanda -0.19 0.04562 NA
49 hsa-miR-146b-5p ADAM15 -0.03 0.77608 0.15 0.02035 miRanda -0.2 0.01006 NA
50 hsa-miR-188-5p ADAM22 0.48 7.0E-5 -0.03 0.71252 mirMAP -0.17 0.02779 NA
51 hsa-miR-484 ADAM33 0.16 0.10284 -0.13 0.01251 MirTarget -0.16 0.00648 NA
52 hsa-miR-133b ADAM9 -0.56 0 0.31 0.0258 miRanda -0.27 0.0393 NA
53 hsa-miR-548p ADAMTS15 0.2 0.015 -0.07 0.35503 miRNATAP -0.21 0.04641 NA
54 hsa-miR-654-5p ADAMTS17 0.2 0.03487 -0.01 0.84529 MirTarget -0.12 0.02029 NA
55 hsa-miR-1299 ADAMTS6 -0.13 0.28393 0.15 0.02621 MirTarget; PITA -0.14 0.02214 NA
56 hsa-miR-587 ADAMTS6 0.02 0.78578 0.15 0.02621 PITA; miRNATAP -0.24 0.02451 NA
57 hsa-miR-921 ADAMTS6 -0.02 0.78653 0.15 0.02621 MirTarget; PITA; miRNATAP -0.32 0.00595 NA
58 hsa-miR-1200 ADARB1 0.02 0.78612 0.02 0.7471 MirTarget; mirMAP; miRNATAP -0.17 0.02188 NA
59 hsa-miR-518d-5p ADARB1 -0.17 0.02136 0.02 0.7471 MirTarget; miRNATAP -0.17 0.03472 NA
60 hsa-miR-34c-3p ADCY2 0.08 0.32894 -0.14 0.00579 mirMAP -0.14 0.0416 NA
61 hsa-miR-342-3p ADCY3 -0.2 3.0E-5 0.41 0 miRanda -0.58 0.00379 NA
62 hsa-miR-1224-5p ADCY9 0.15 0.23912 -0.4 0 mirMAP -0.13 0.03606 NA
63 hsa-miR-107 ADCYAP1 0.02 0.45295 -0.11 0.05017 MirTarget; PITA; miRanda; miRNATAP -0.9 0.00075 NA
64 hsa-miR-324-3p ADCYAP1 -0.15 0.01636 -0.11 0.05017 PITA; miRNATAP -0.23 0.0175 NA
65 hsa-miR-1179 ADCYAP1R1 0.05 0.53482 -0.12 0.09847 mirMAP -0.25 0.01368 NA
66 hsa-miR-558 ADGRL1 -0.15 0.04577 0.2 0.01371 miRNATAP -0.27 0.02985 NA
67 hsa-miR-1244 ADGRL4 0.24 0.08574 -0.42 0.00469 MirTarget -0.28 0.02707 NA
68 hsa-miR-502-5p ADHFE1 0.3 0.00093 -0.6 0 miRNATAP -0.48 0.00012 NA
69 hsa-miR-612 ADPRH 0.07 0.39432 -0.04 0.26628 miRNATAP -0.14 0.0085 NA
70 hsa-miR-107 ADRB2 0.02 0.45295 -0.16 0.00256 miRanda -0.55 0.04248 NA
71 hsa-miR-1275 ADRB2 0.24 0.00451 -0.16 0.00256 MirTarget -0.15 0.0338 NA
72 hsa-miR-1283 ADSS -0.15 0.08004 0.21 0.02668 MirTarget; PITA -0.26 0.04606 NA
73 hsa-miR-1303 AFF1 0.15 0.048 -0.42 0 mirMAP -0.3 0.01218 NA
74 hsa-miR-875-3p AFF1 0.18 0.096 -0.42 0 PITA -0.17 0.03928 NA
75 hsa-miR-107 AFF2 0.02 0.45295 -0.06 0.2719 mirMAP; miRNATAP -0.63 0.02323 NA
76 hsa-miR-1179 AFF2 0.05 0.53482 -0.06 0.2719 mirMAP -0.2 0.00746 NA
77 hsa-miR-548p AFF2 0.2 0.015 -0.06 0.2719 mirMAP -0.18 0.01428 NA
78 hsa-miR-600 AFF2 0.01 0.90987 -0.06 0.2719 PITA; mirMAP -0.23 0.00315 NA
79 hsa-miR-525-5p AFF4 -0.03 0.64643 -0.05 0.47883 MirTarget; PITA -0.27 0.02075 NA
80 hsa-miR-342-3p AFMID -0.2 3.0E-5 0.28 0 miRanda -0.31 0.0192 NA
81 hsa-miR-129-5p AGAP6 0.13 0.23985 0.25 0.07098 miRanda -0.33 0.02593 NA
82 hsa-miR-622 AGFG2 0.32 0.00092 -0.14 0.02367 mirMAP -0.15 0.03176 NA
83 hsa-miR-875-3p AGFG2 0.18 0.096 -0.14 0.02367 miRNATAP -0.22 0.00073 NA
84 hsa-miR-146b-3p AGGF1 0.1 0.33957 -0.13 0.0581 miRNATAP -0.17 0.02146 NA
85 hsa-miR-558 AGO2 -0.15 0.04577 0.62 0 miRNATAP -0.41 0.01325 NA
86 hsa-miR-133b AHCY -0.56 0 0.85 0 miRanda -0.48 7.0E-5 NA
87 hsa-miR-1253 AHCYL1 0 0.96973 -0.14 0.06228 PITA; miRNATAP -0.25 0.03423 NA
88 hsa-miR-875-3p AHCYL2 0.18 0.096 -1.65 0 mirMAP -0.76 0.00485 NA
89 hsa-miR-875-3p AHNAK 0.18 0.096 -1.18 0 PITA -0.46 0.0226 NA
90 hsa-miR-558 AIG1 -0.15 0.04577 0.26 0.00513 miRNATAP -0.29 0.04277 NA
91 hsa-miR-525-5p AIM1 -0.03 0.64643 -0.18 0.10342 miRNATAP -0.35 0.04945 NA
92 hsa-miR-548b-3p AK4 -0.13 0.08239 0.21 0.03542 mirMAP -0.35 0.02197 NA
93 hsa-miR-875-3p AK7 0.18 0.096 -0.06 0.2184 PITA -0.12 0.01237 NA
94 hsa-miR-637 AKAP13 0.19 0.15577 -0.46 0 mirMAP -0.16 0.02482 NA
95 hsa-miR-665 AKAP13 0.29 0.01654 -0.46 0 miRNATAP -0.23 0.00218 NA
96 hsa-miR-1289 AKIRIN1 0.1 0.12893 -0.04 0.44188 miRNATAP -0.21 0.02586 NA
97 hsa-miR-369-3p AKT1 -0.05 0.45428 0.05 0.23182 miRNATAP -0.13 0.03641 NA
98 hsa-miR-342-3p AKT2 -0.2 3.0E-5 0.13 0.01365 mirMAP -0.26 0.0332 NA
99 hsa-miR-1275 AKT3 0.24 0.00451 -0.69 1.0E-5 PITA -0.55 0.01043 NA
100 hsa-miR-637 AKT3 0.19 0.15577 -0.69 1.0E-5 PITA -0.3 0.02663 NA
101 hsa-miR-324-3p ALDOA -0.15 0.01636 0.18 0.00366 miRNAWalker2 validate -0.24 0.03509 NA
102 hsa-miR-1303 ALG10B 0.15 0.048 -0.1 0.37752 MirTarget -0.5 0.00387 NA
103 hsa-miR-661 ALOX15 0.05 0.57941 0.01 0.91189 PITA -0.19 0.02666 NA
104 hsa-miR-1825 ALS2 -0.09 0.2173 0.13 0.0695 miRNATAP -0.29 0.00967 NA
105 hsa-miR-548c-3p AMER1 -0.1 0.19562 0.31 1.0E-5 miRNATAP -0.22 0.03373 NA
106 hsa-miR-342-3p AMMECR1L -0.2 3.0E-5 0.23 0.00049 mirMAP -0.44 0.00599 NA
107 hsa-miR-330-3p AMOT -0.09 0.47557 0.29 0.01112 MirTarget; PITA; miRNATAP -0.24 0.01808 NA
108 hsa-miR-875-3p AMOT 0.18 0.096 0.29 0.01112 MirTarget -0.29 0.01365 NA
109 hsa-miR-1275 AMOTL1 0.24 0.00451 -0.17 0.0013 miRNATAP -0.18 0.01113 NA
110 hsa-miR-330-3p AMOTL2 -0.09 0.47557 0.13 0.01176 mirMAP -0.13 0.00174 NA
111 hsa-miR-139-5p ANAPC7 -0.96 0 0.4 0 miRanda -0.2 1.0E-5 NA
112 hsa-miR-548c-3p ANGEL1 -0.1 0.19562 0.32 1.0E-5 MirTarget; PITA; mirMAP -0.22 0.03941 NA
113 hsa-miR-133b ANGPT2 -0.56 0 0.42 0.00033 miRanda -0.28 0.01366 NA
114 hsa-miR-1283 ANGPTL5 -0.15 0.08004 0.03 0.49375 MirTarget; miRNATAP -0.12 0.03433 NA
115 hsa-miR-1179 ANK1 0.05 0.53482 0.11 0.05395 PITA; miRNATAP -0.16 0.03152 NA
116 hsa-miR-600 ANK1 0.01 0.90987 0.11 0.05395 PITA; miRNATAP -0.19 0.01225 NA
117 hsa-miR-1275 ANK2 0.24 0.00451 -1.01 0 MirTarget -0.61 0.00114 NA
118 hsa-miR-502-5p ANK2 0.3 0.00093 -1.01 0 PITA -0.6 0.0004 NA
119 hsa-miR-575 ANK3 0.18 0.03642 -0.55 0 MirTarget; PITA -0.3 0.03031 NA
120 hsa-miR-129-5p ANKH 0.13 0.23985 0.14 0.13002 miRanda -0.2 0.03214 NA
121 hsa-miR-623 ANKH -0.03 0.66704 0.14 0.13002 mirMAP -0.3 0.04457 NA
122 hsa-miR-601 ANKIB1 -0.23 0.0006 0.18 0.03225 miRNATAP -0.35 0.01661 NA
123 hsa-miR-342-3p ANKLE2 -0.2 3.0E-5 0.22 0.00015 miRanda -0.35 0.01056 NA
124 hsa-miR-188-5p ANKRD12 0.48 7.0E-5 -0.92 0 PITA -0.45 0.00061 NA
125 hsa-miR-502-5p ANKRD12 0.3 0.00093 -0.92 0 PITA; miRNATAP -0.51 0.00501 NA
126 hsa-miR-188-5p ANKRD13A 0.48 7.0E-5 -0.5 0 mirMAP -0.22 0.00529 NA
127 hsa-miR-548c-3p ANKRD18B -0.1 0.19562 0.18 0.00767 MirTarget -0.27 0.00513 NA
128 hsa-miR-139-5p ANKRD27 -0.96 0 0.25 0.00012 miRanda -0.1 0.01931 NA
129 hsa-miR-1253 ANKRD28 0 0.96973 -0.17 0.07767 PITA; miRNATAP -0.3 0.04496 NA
130 hsa-miR-520h ANKRD36 -0.03 0.73371 -0.03 0.84136 mirMAP -0.51 0.03572 NA
131 hsa-miR-133b ANKRD46 -0.56 0 0.3 0.00622 miRanda -0.25 0.01592 NA
132 hsa-miR-1253 ANKRD49 0 0.96973 -0.03 0.75692 MirTarget; miRNATAP -0.35 0.04139 NA
133 hsa-miR-342-3p ANKRD52 -0.2 3.0E-5 0.17 0.0025 PITA; miRNATAP -0.39 0.00243 NA
134 hsa-miR-139-5p ANKS1A -0.96 0 0.14 0.02401 miRanda -0.11 0.00827 NA
135 hsa-miR-558 ANKS6 -0.15 0.04577 0.38 0 mirMAP -0.23 0.02942 NA
136 hsa-miR-342-3p ANLN -0.2 3.0E-5 1.35 0 miRanda -1.97 0.00013 NA
137 hsa-miR-637 ANO10 0.19 0.15577 -0.55 0 MirTarget -0.23 0.01084 NA
138 hsa-miR-1179 ANO3 0.05 0.53482 -0 0.96333 MirTarget; miRNATAP -0.2 0.00968 NA
139 hsa-miR-558 ANP32A -0.15 0.04577 0.1 0.10261 miRNATAP -0.18 0.03603 NA
140 hsa-miR-558 ANP32E -0.15 0.04577 -0.05 0.65057 miRNATAP -0.34 0.03538 NA
141 hsa-miR-296-3p ANTXR1 -0.06 0.54339 -0.15 0.28155 MirTarget; PITA; miRanda -0.52 0.00147 NA
142 hsa-miR-409-3p ANXA11 -0.01 0.91657 -0.1 0.19622 mirMAP -0.2 0.0253 NA
143 hsa-miR-484 ANXA11 0.16 0.10284 -0.1 0.19622 miRNAWalker2 validate; mirMAP -0.2 0.02336 NA
144 hsa-miR-654-5p ANXA11 0.2 0.03487 -0.1 0.19622 MirTarget -0.19 0.04292 NA
145 hsa-miR-1303 AP1AR 0.15 0.048 -0.03 0.78385 MirTarget -0.3 0.03145 NA
146 hsa-miR-129-5p AP1G1 0.13 0.23985 -0.16 0.02465 mirMAP -0.21 0.00361 NA
147 hsa-miR-665 AP1G1 0.29 0.01654 -0.16 0.02465 PITA; miRNATAP -0.13 0.03849 NA
148 hsa-miR-139-5p AP1S1 -0.96 0 0.64 0 miRanda -0.24 0.00445 NA
149 hsa-miR-342-3p AP2A1 -0.2 3.0E-5 0.13 0.01203 miRanda -0.26 0.03436 NA
150 hsa-miR-607 AP2B1 -0.07 0.34593 0.13 0.15931 miRNATAP -0.31 0.02535 NA

Over-represented Gene Ontology Biological Process

NumGOOverlapSizeP ValueAdj. P Value
1 POSITIVE REGULATION OF GENE EXPRESSION 390 1733 7.477e-23 3.479e-19
2 REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 394 1784 1.63e-21 3.793e-18
3 POSITIVE REGULATION OF BIOSYNTHETIC PROCESS 395 1805 8.118e-21 1.259e-17
4 EMBRYO DEVELOPMENT ENDING IN BIRTH OR EGG HATCHING 147 554 7.197e-15 8.008e-12
5 REGULATION OF ORGANELLE ORGANIZATION 262 1178 8.605e-15 8.008e-12
6 CELL DEVELOPMENT 303 1426 3.045e-14 2.362e-11
7 EMBRYO DEVELOPMENT 208 894 6.183e-14 3.596e-11
8 POSITIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 228 1004 5.564e-14 3.596e-11
9 NEUROGENESIS 297 1402 8.398e-14 4.342e-11
10 REGULATION OF MULTICELLULAR ORGANISMAL DEVELOPMENT 342 1672 1.339e-13 6.231e-11
11 NEGATIVE REGULATION OF GENE EXPRESSION 311 1493 1.918e-13 8.111e-11
12 ANATOMICAL STRUCTURE FORMATION INVOLVED IN MORPHOGENESIS 217 957 2.768e-13 1.073e-10
13 TISSUE DEVELOPMENT 310 1518 2.697e-12 9.655e-10
14 EMBRYONIC MORPHOGENESIS 136 539 4.206e-12 1.398e-09
15 REGULATION OF CELL DIFFERENTIATION 302 1492 1.57e-11 4.871e-09
16 REGULATION OF CELL DEVELOPMENT 188 836 2.504e-11 7.281e-09
17 POSITIVE REGULATION OF CELL COMMUNICATION 307 1532 3.498e-11 9.575e-09
18 RESPONSE TO ENDOGENOUS STIMULUS 292 1450 6.408e-11 1.569e-08
19 REGULATION OF ANATOMICAL STRUCTURE MORPHOGENESIS 219 1021 6.149e-11 1.569e-08
20 NEGATIVE REGULATION OF NITROGEN COMPOUND METABOLIC PROCESS 303 1517 7.011e-11 1.631e-08
21 PROTEIN LOCALIZATION 350 1805 9.026e-11 2e-08
22 REGULATION OF CELLULAR COMPONENT MOVEMENT 174 771 1.058e-10 2.237e-08
23 REGULATION OF CYTOSKELETON ORGANIZATION 124 502 1.646e-10 3.33e-08
24 POSITIVE REGULATION OF MOLECULAR FUNCTION 346 1791 1.866e-10 3.524e-08
25 CARDIOVASCULAR SYSTEM DEVELOPMENT 176 788 1.969e-10 3.524e-08
26 CIRCULATORY SYSTEM DEVELOPMENT 176 788 1.969e-10 3.524e-08
27 ORGAN MORPHOGENESIS 185 841 2.477e-10 4.269e-08
28 MUSCLE STRUCTURE DEVELOPMENT 110 432 2.711e-10 4.505e-08
29 CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 125 513 3.524e-10 5.655e-08
30 INTRACELLULAR SIGNAL TRANSDUCTION 308 1572 4.463e-10 6.77e-08
31 CELLULAR RESPONSE TO ENDOGENOUS STIMULUS 213 1008 4.581e-10 6.77e-08
32 NEGATIVE REGULATION OF TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 166 740 4.656e-10 6.77e-08
33 NEURON DIFFERENTIATION 189 874 6.819e-10 9.332e-08
34 MUSCLE CELL DIFFERENTIATION 70 237 6.654e-10 9.332e-08
35 TUBE FORMATION 46 129 7.843e-10 1.043e-07
36 PHOSPHATE CONTAINING COMPOUND METABOLIC PROCESS 371 1977 1.511e-09 1.954e-07
37 ESTABLISHMENT OF LOCALIZATION IN CELL 322 1676 1.643e-09 2.066e-07
38 REGULATION OF CELLULAR RESPONSE TO STRESS 155 691 1.787e-09 2.189e-07
39 HEAD DEVELOPMENT 158 709 2.024e-09 2.415e-07
40 REGULATION OF NERVOUS SYSTEM DEVELOPMENT 165 750 2.367e-09 2.754e-07
41 POSITIVE REGULATION OF RESPONSE TO STIMULUS 362 1929 2.468e-09 2.801e-07
42 NEURON PROJECTION DEVELOPMENT 128 545 2.581e-09 2.859e-07
43 CELLULAR COMPONENT MORPHOGENESIS 190 900 4.511e-09 4.881e-07
44 RESPONSE TO GROWTH FACTOR 114 475 5.306e-09 5.611e-07
45 TUBE MORPHOGENESIS 85 323 5.518e-09 5.706e-07
46 PROTEIN PHOSPHORYLATION 197 944 6.045e-09 5.984e-07
47 NEURAL TUBE FORMATION 36 94 5.995e-09 5.984e-07
48 REGULATION OF DEVELOPMENTAL GROWTH 78 289 6.978e-09 6.764e-07
49 REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 315 1656 7.497e-09 6.977e-07
50 REGULATION OF NEURON DIFFERENTIATION 128 554 7.445e-09 6.977e-07
51 REGULATION OF PHOSPHORUS METABOLIC PROCESS 307 1618 1.548e-08 1.412e-06
52 CELLULAR RESPONSE TO OXYGEN CONTAINING COMPOUND 170 799 1.702e-08 1.523e-06
53 REGULATION OF CELLULAR COMPONENT BIOGENESIS 164 767 2.152e-08 1.887e-06
54 REGULATION OF PROTEIN MODIFICATION PROCESS 321 1710 2.19e-08 1.887e-06
55 CENTRAL NERVOUS SYSTEM DEVELOPMENT 182 872 2.316e-08 1.959e-06
56 CELL PROLIFERATION 147 672 2.631e-08 2.186e-06
57 TRANSCRIPTION FROM RNA POLYMERASE II PROMOTER 156 724 2.823e-08 2.304e-06
58 EPITHELIUM DEVELOPMENT 194 945 2.922e-08 2.309e-06
59 CELL CYCLE 256 1316 2.978e-08 2.309e-06
60 POSITIVE REGULATION OF PROTEIN MODIFICATION PROCESS 226 1135 2.938e-08 2.309e-06
61 POSITIVE REGULATION OF DEVELOPMENTAL PROCESS 227 1142 3.169e-08 2.417e-06
62 MOVEMENT OF CELL OR SUBCELLULAR COMPONENT 249 1275 3.288e-08 2.468e-06
63 POSITIVE REGULATION OF PHOSPHATE METABOLIC PROCESS 209 1036 3.524e-08 2.562e-06
64 POSITIVE REGULATION OF PHOSPHORUS METABOLIC PROCESS 209 1036 3.524e-08 2.562e-06
65 ESTABLISHMENT OF PROTEIN LOCALIZATION 273 1423 3.767e-08 2.697e-06
66 REGULATION OF CELL PROJECTION ORGANIZATION 126 558 4.016e-08 2.831e-06
67 GLAND DEVELOPMENT 96 395 4.443e-08 3.086e-06
68 REGULATION OF GROWTH 139 633 4.951e-08 3.338e-06
69 CELLULAR RESPONSE TO ORGANIC SUBSTANCE 341 1848 4.906e-08 3.338e-06
70 PEPTIDYL AMINO ACID MODIFICATION 175 841 5.412e-08 3.597e-06
71 CHROMATIN MODIFICATION 122 539 5.726e-08 3.753e-06
72 CELLULAR RESPONSE TO LIPID 107 457 6.16e-08 3.981e-06
73 NEURON DEVELOPMENT 148 687 6.507e-08 4.06e-06
74 POSITIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 227 1152 6.615e-08 4.06e-06
75 REGULATION OF CELL CYCLE 193 949 6.541e-08 4.06e-06
76 CELL PROJECTION ORGANIZATION 185 902 6.632e-08 4.06e-06
77 NEGATIVE REGULATION OF CELLULAR COMPONENT ORGANIZATION 147 684 8.426e-08 5.091e-06
78 MORPHOGENESIS OF EMBRYONIC EPITHELIUM 43 134 9.642e-08 5.752e-06
79 TUBE DEVELOPMENT 123 552 1.265e-07 7.355e-06
80 REGULATION OF CELL MORPHOGENESIS 123 552 1.265e-07 7.355e-06
81 STRIATED MUSCLE CELL DIFFERENTIATION 51 173 1.418e-07 8.148e-06
82 POSITIVE REGULATION OF CATALYTIC ACTIVITY 285 1518 1.457e-07 8.27e-06
83 POSITIVE REGULATION OF MULTICELLULAR ORGANISMAL PROCESS 265 1395 1.482e-07 8.31e-06
84 REGULATION OF EMBRYONIC DEVELOPMENT 38 114 1.751e-07 9.697e-06
85 CELLULAR MACROMOLECULE LOCALIZATION 238 1234 1.942e-07 1.057e-05
86 PHOSPHORYLATION 237 1228 1.953e-07 1.057e-05
87 REGULATION OF NEURON PROJECTION DEVELOPMENT 96 408 2.278e-07 1.205e-05
88 REGULATION OF CELLULAR PROTEIN LOCALIZATION 122 552 2.262e-07 1.205e-05
89 POSITIVE REGULATION OF PROTEIN METABOLIC PROCESS 279 1492 2.868e-07 1.499e-05
90 ENDOMEMBRANE SYSTEM ORGANIZATION 106 465 2.915e-07 1.507e-05
91 MORPHOGENESIS OF AN EPITHELIUM 94 400 3.223e-07 1.642e-05
92 SKELETAL SYSTEM DEVELOPMENT 104 455 3.282e-07 1.642e-05
93 HEART DEVELOPMENT 106 466 3.257e-07 1.642e-05
94 ACTIN FILAMENT BASED PROCESS 103 450 3.481e-07 1.723e-05
95 REGULATION OF CELL PROLIFERATION 279 1496 3.646e-07 1.786e-05
96 REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 82 337 3.97e-07 1.924e-05
97 POSITIVE REGULATION OF GROWTH 63 238 4.013e-07 1.925e-05
98 NEURON PROJECTION MORPHOGENESIS 94 402 4.094e-07 1.944e-05
99 REPRODUCTIVE SYSTEM DEVELOPMENT 95 408 4.363e-07 2.051e-05
100 REGULATION OF ACTIN FILAMENT BASED PROCESS 77 312 4.888e-07 2.264e-05
101 LOCOMOTION 216 1114 4.914e-07 2.264e-05
102 NUCLEAR TRANSPORT 85 355 5.088e-07 2.321e-05
103 POSITIVE REGULATION OF KINASE ACTIVITY 108 482 5.52e-07 2.446e-05
104 RESPONSE TO HORMONE 179 893 5.433e-07 2.446e-05
105 RESPONSE TO ORGANIC CYCLIC COMPOUND 183 917 5.501e-07 2.446e-05
106 REGULATION OF TRANSPORT 327 1804 5.644e-07 2.477e-05
107 TISSUE MORPHOGENESIS 117 533 5.756e-07 2.48e-05
108 BEHAVIOR 114 516 5.715e-07 2.48e-05
109 REGULATION OF EPITHELIAL CELL MIGRATION 48 166 6.119e-07 2.578e-05
110 CENTRAL NERVOUS SYSTEM NEURON DIFFERENTIATION 48 166 6.119e-07 2.578e-05
111 DEVELOPMENTAL PROCESS INVOLVED IN REPRODUCTION 129 602 6.15e-07 2.578e-05
112 RESPONSE TO OXYGEN CONTAINING COMPOUND 259 1381 6.205e-07 2.578e-05
113 LOCOMOTORY BEHAVIOR 51 181 6.617e-07 2.725e-05
114 CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION 87 368 6.685e-07 2.728e-05
115 MITOTIC CELL CYCLE 157 766 6.956e-07 2.814e-05
116 POSITIVE REGULATION OF CELL PROLIFERATION 165 814 7.445e-07 2.986e-05
117 RESPONSE TO OXYGEN LEVELS 76 311 8.717e-07 3.467e-05
118 POSITIVE REGULATION OF INTRACELLULAR SIGNAL TRANSDUCTION 175 876 9.123e-07 3.597e-05
119 NEURAL TUBE DEVELOPMENT 44 149 9.428e-07 3.615e-05
120 POSTTRANSCRIPTIONAL REGULATION OF GENE EXPRESSION 101 448 9.478e-07 3.615e-05
121 CELL CYCLE PROCESS 209 1081 9.365e-07 3.615e-05
122 DEVELOPMENTAL GROWTH 80 333 9.447e-07 3.615e-05
123 REGULATION OF MUSCLE TISSUE DEVELOPMENT 34 103 9.862e-07 3.731e-05
124 GROWTH 94 410 1.035e-06 3.882e-05
125 REGULATION OF PROTEIN LOCALIZATION 187 950 1.071e-06 3.985e-05
126 BIOLOGICAL ADHESION 200 1032 1.37e-06 5.06e-05
127 RESPONSE TO LIPID 176 888 1.43e-06 5.238e-05
128 VASCULATURE DEVELOPMENT 104 469 1.48e-06 5.379e-05
129 REGULATION OF KINASE ACTIVITY 157 776 1.553e-06 5.601e-05
130 REGULATION OF CELLULAR AMIDE METABOLIC PROCESS 83 354 1.704e-06 6.099e-05
131 REGULATION OF MAPK CASCADE 137 660 1.756e-06 6.238e-05
132 TELENCEPHALON DEVELOPMENT 59 228 2.053e-06 7.237e-05
133 CELLULAR RESPONSE TO HORMONE STIMULUS 118 552 2.083e-06 7.287e-05
134 REGULATION OF DENDRITE DEVELOPMENT 37 120 2.175e-06 7.552e-05
135 CHROMOSOME ORGANIZATION 195 1009 2.253e-06 7.764e-05
136 EMBRYONIC ORGAN DEVELOPMENT 92 406 2.271e-06 7.77e-05
137 POSITIVE REGULATION OF CELL DIFFERENTIATION 164 823 2.352e-06 7.987e-05
138 FOREBRAIN DEVELOPMENT 83 357 2.431e-06 8.198e-05
139 NUCLEOBASE CONTAINING COMPOUND TRANSPORT 53 199 2.654e-06 8.884e-05
140 ENZYME LINKED RECEPTOR PROTEIN SIGNALING PATHWAY 141 689 2.797e-06 9.296e-05
141 REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 103 470 2.904e-06 9.584e-05
142 CYTOSKELETON ORGANIZATION 166 838 2.948e-06 9.66e-05
143 REGULATION OF MUSCLE ORGAN DEVELOPMENT 33 103 2.984e-06 9.708e-05
144 CELLULAR RESPONSE TO STRESS 284 1565 3.073e-06 9.93e-05
145 CHONDROCYTE DIFFERENTIATION 23 60 3.173e-06 0.0001015
146 POSITIVE REGULATION OF CELL CYCLE 78 332 3.185e-06 0.0001015
147 CELL DIVISION 101 460 3.31e-06 0.0001048
148 IN UTERO EMBRYONIC DEVELOPMENT 74 311 3.459e-06 0.0001088
149 CELL MOTILITY 165 835 3.668e-06 0.000113
150 LOCALIZATION OF CELL 165 835 3.668e-06 0.000113
151 POSITIVE REGULATION OF DEVELOPMENTAL GROWTH 44 156 3.651e-06 0.000113
152 CENTRAL NERVOUS SYSTEM NEURON AXONOGENESIS 14 27 4.128e-06 0.0001264
153 MUSCLE TISSUE DEVELOPMENT 67 275 4.217e-06 0.0001274
154 NUCLEAR EXPORT 42 147 4.205e-06 0.0001274
155 SINGLE ORGANISM BEHAVIOR 87 384 4.264e-06 0.000128
156 POSITIVE REGULATION OF CELL MORPHOGENESIS INVOLVED IN DIFFERENTIATION 45 162 4.442e-06 0.0001325
157 TRANSMEMBRANE RECEPTOR PROTEIN TYROSINE KINASE SIGNALING PATHWAY 107 498 4.839e-06 0.0001434
158 SENSORY ORGAN DEVELOPMENT 106 493 5.178e-06 0.0001525
159 SEX DIFFERENTIATION 65 266 5.244e-06 0.0001535
160 REGULATION OF OSSIFICATION 48 178 5.324e-06 0.0001548
161 CELL JUNCTION ASSEMBLY 38 129 5.392e-06 0.0001558
162 REGULATION OF CELLULAR COMPONENT SIZE 78 337 5.753e-06 0.0001652
163 CHROMATIN ORGANIZATION 135 663 5.936e-06 0.0001694
164 REGULATION OF CHROMOSOME ORGANIZATION 67 278 6.235e-06 0.0001769
165 ADULT BEHAVIOR 39 135 6.837e-06 0.0001928
166 RNA LOCALIZATION 49 185 7.329e-06 0.0002054
167 CELL PART MORPHOGENESIS 129 633 9.111e-06 0.0002539
168 POSITIVE REGULATION OF TRANSFERASE ACTIVITY 126 616 9.597e-06 0.0002658
169 REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 51 197 9.68e-06 0.0002665
170 PROTEIN AUTOPHOSPHORYLATION 50 192 9.886e-06 0.0002706
171 CARTILAGE DEVELOPMENT 41 147 1.04e-05 0.0002813
172 CENTRAL NERVOUS SYSTEM PROJECTION NEURON AXONOGENESIS 12 22 1.034e-05 0.0002813
173 IMMUNE SYSTEM DEVELOPMENT 120 582 1.057e-05 0.0002824
174 POSITIVE REGULATION OF CELL DEVELOPMENT 101 472 1.059e-05 0.0002824
175 EPITHELIAL CELL DIFFERENTIATION 105 495 1.062e-05 0.0002824
176 POSITIVE REGULATION OF OSTEOBLAST DIFFERENTIATION 22 60 1.197e-05 0.0003165
177 OSSIFICATION 61 251 1.207e-05 0.0003173
178 REGULATION OF ENDOTHELIAL CELL MIGRATION 34 114 1.231e-05 0.0003217
179 REGULATION OF CELL DEATH 265 1472 1.242e-05 0.0003229
180 APPENDAGE DEVELOPMENT 45 169 1.466e-05 0.000377
181 LIMB DEVELOPMENT 45 169 1.466e-05 0.000377
182 WNT SIGNALING PATHWAY 79 351 1.484e-05 0.0003795
183 CELL JUNCTION ORGANIZATION 48 185 1.637e-05 0.0004139
184 REGULATION OF CELL CYCLE PROCESS 115 558 1.637e-05 0.0004139
185 REGULATION OF DENDRITE MORPHOGENESIS 25 74 1.646e-05 0.0004139
186 REGULATION OF CELLULAR LOCALIZATION 233 1277 1.714e-05 0.0004288
187 REGULATION OF ANATOMICAL STRUCTURE SIZE 100 472 1.798e-05 0.0004473
188 NITROGEN COMPOUND TRANSPORT 106 507 1.849e-05 0.0004576
189 DENDRITE DEVELOPMENT 26 79 1.904e-05 0.0004645
190 EPITHELIAL CELL DEVELOPMENT 48 186 1.907e-05 0.0004645
191 NEGATIVE REGULATION OF ORGANELLE ORGANIZATION 85 387 1.897e-05 0.0004645
192 NEGATIVE REGULATION OF CELL CYCLE 93 433 2.002e-05 0.0004852
193 ACTIN FILAMENT BASED MOVEMENT 29 93 2.075e-05 0.0004994
194 ESTABLISHMENT OR MAINTENANCE OF CELL POLARITY 39 141 2.082e-05 0.0004994
195 POSITIVE REGULATION OF CELLULAR PROTEIN LOCALIZATION 80 360 2.131e-05 0.0005085
196 POSITIVE REGULATION OF OSSIFICATION 27 84 2.152e-05 0.0005109
197 REGULATION OF OSTEOBLAST DIFFERENTIATION 33 112 2.167e-05 0.0005119
198 TRNA TRANSPORT 15 34 2.3e-05 0.0005406
199 RESPONSE TO WOUNDING 115 563 2.47e-05 0.0005774
200 REGULATION OF CHROMATIN ORGANIZATION 41 152 2.482e-05 0.0005775
201 POSITIVE REGULATION OF MAPK CASCADE 99 470 2.524e-05 0.0005842
202 POSITIVE REGULATION OF NEURON DIFFERENTIATION 70 306 2.546e-05 0.0005865
203 PALATE DEVELOPMENT 27 85 2.732e-05 0.0006263
204 REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 54 220 2.769e-05 0.0006316
205 POSITIVE REGULATION OF CELL CYCLE PROCESS 59 247 2.869e-05 0.0006511
206 REGULATION OF ORGAN MORPHOGENESIS 58 242 3.01e-05 0.00068
207 NEURON PROJECTION GUIDANCE 51 205 3.113e-05 0.0006997
208 POSITIVE REGULATION OF ORGANELLE ORGANIZATION 116 573 3.431e-05 0.0007675
209 STEM CELL DIFFERENTIATION 48 190 3.45e-05 0.0007681
210 RESPONSE TO STEROID HORMONE 103 497 3.51e-05 0.0007777
211 REGULATION OF SODIUM ION TRANSPORT 25 77 3.545e-05 0.0007817
212 MEMBRANE DISASSEMBLY 18 47 3.728e-05 0.0008143
213 NUCLEAR ENVELOPE DISASSEMBLY 18 47 3.728e-05 0.0008143
214 MODULATION BY SYMBIONT OF HOST CELLULAR PROCESS 13 28 4.18e-05 0.0009088
215 REGULATION OF BINDING 65 283 4.27e-05 0.0009242
216 REGIONALIZATION 70 311 4.422e-05 0.0009526
217 CELLULAR RESPONSE TO ORGANIC CYCLIC COMPOUND 97 465 4.504e-05 0.0009659
218 POSITIVE REGULATION OF CELL CYCLE G2 M PHASE TRANSITION 10 18 4.715e-05 0.001006
219 PROTEIN LOCALIZATION TO NUCLEUS 41 156 4.77e-05 0.001013
220 POSITIVE REGULATION OF NUCLEOCYTOPLASMIC TRANSPORT 34 121 4.834e-05 0.001022
221 CHEMICAL HOMEOSTASIS 165 874 5.041e-05 0.001056
222 POSITIVE REGULATION OF LOCOMOTION 89 420 5.037e-05 0.001056
223 EMBRYONIC ORGAN MORPHOGENESIS 64 279 5.07e-05 0.001058
224 NEGATIVE REGULATION OF CELL CYCLE PROCESS 52 214 5.141e-05 0.001068
225 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORT 18 48 5.179e-05 0.001071
226 BRANCHING INVOLVED IN URETERIC BUD MORPHOGENESIS 17 44 5.347e-05 0.001101
227 RESPONSE TO ACID CHEMICAL 71 319 5.719e-05 0.001167
228 REGULATION OF MAP KINASE ACTIVITY 71 319 5.719e-05 0.001167
229 REGULATION OF PROTEIN POLYMERIZATION 44 173 6.039e-05 0.001227
230 ANTERIOR POSTERIOR PATTERN SPECIFICATION 48 194 6.071e-05 0.001228
231 REGULATION OF TRANSFERASE ACTIVITY 176 946 6.503e-05 0.00131
232 REGULATION OF RESPONSE TO STRESS 259 1468 6.609e-05 0.00132
233 REGULATION OF CELL CYCLE ARREST 31 108 6.589e-05 0.00132
234 REPRODUCTION 232 1297 6.72e-05 0.001336
235 REGULATION OF STEM CELL DIFFERENTIATION 32 113 6.752e-05 0.001337
236 REGULATION OF MRNA METABOLIC PROCESS 33 118 6.868e-05 0.001343
237 RIBONUCLEOPROTEIN COMPLEX LOCALIZATION 33 118 6.868e-05 0.001343
238 RAS PROTEIN SIGNAL TRANSDUCTION 38 143 6.862e-05 0.001343
239 REGULATION OF WNT SIGNALING PATHWAY 69 310 7.207e-05 0.001403
240 MODULATION BY VIRUS OF HOST MORPHOLOGY OR PHYSIOLOGY 15 37 7.629e-05 0.001479
241 HEART MORPHOGENESIS 51 212 7.956e-05 0.001536
242 CELL CELL ADHESION 120 608 8.017e-05 0.001541
243 POSITIVE REGULATION OF CYTOSKELETON ORGANIZATION 44 175 8.076e-05 0.001546
244 COVALENT CHROMATIN MODIFICATION 75 345 8.111e-05 0.001547
245 MESENCHYMAL CELL DIFFERENTIATION 36 134 8.243e-05 0.001566
246 MULTICELLULAR ORGANISM GROWTH 24 76 8.311e-05 0.001566
247 NUCLEAR IMPORT 35 129 8.28e-05 0.001566
248 CANONICAL WNT SIGNALING PATHWAY 28 95 8.775e-05 0.001646
249 RESPIRATORY SYSTEM DEVELOPMENT 48 197 9.113e-05 0.001703
250 SISTER CHROMATID SEGREGATION 44 176 9.312e-05 0.001733
251 CARDIAC MUSCLE TISSUE DEVELOPMENT 37 140 9.61e-05 0.001781
252 POSITIVE REGULATION OF STRESS ACTIVATED PROTEIN KINASE SIGNALING CASCADE 36 135 9.728e-05 0.001792
253 BLOOD VESSEL MORPHOGENESIS 78 364 9.743e-05 0.001792
254 PROTEIN MODIFICATION BY SMALL PROTEIN CONJUGATION OR REMOVAL 163 873 9.994e-05 0.001831
255 POSITIVE REGULATION OF VIRAL GENOME REPLICATION 13 30 0.0001013 0.001842
256 RESPONSE TO EPIDERMAL GROWTH FACTOR 13 30 0.0001013 0.001842
257 REGULATION OF CANONICAL WNT SIGNALING PATHWAY 55 236 0.0001063 0.001925
258 NEGATIVE REGULATION OF CHROMOSOME ORGANIZATION 28 96 0.0001073 0.001928
259 CARDIOCYTE DIFFERENTIATION 28 96 0.0001073 0.001928
260 POSITIVE REGULATION OF SODIUM ION TRANSPORT 14 34 0.0001079 0.001931
261 KIDNEY MORPHOGENESIS 25 82 0.000113 0.002015
262 REGULATION OF ORGAN GROWTH 23 73 0.0001205 0.002141
263 CELL DEATH 183 1001 0.0001245 0.002195
264 CONNECTIVE TISSUE DEVELOPMENT 47 194 0.0001241 0.002195
265 REGULATION OF MUSCLE CELL DIFFERENTIATION 39 152 0.0001259 0.002203
266 MITOTIC NUCLEAR DIVISION 77 361 0.0001258 0.002203
267 REGULATION OF MICROTUBULE BASED PROCESS 56 243 0.0001271 0.002215
268 REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION 18 51 0.0001295 0.002248
269 RESPONSE TO NITROGEN COMPOUND 160 859 0.0001305 0.002257
270 DEVELOPMENT OF PRIMARY SEXUAL CHARACTERISTICS 51 216 0.0001316 0.002269
271 POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 90 437 0.0001338 0.002297
272 HINDBRAIN DEVELOPMENT 36 137 0.0001344 0.0023
273 POSITIVE REGULATION OF BINDING 34 127 0.0001379 0.002351
274 DEVELOPMENTAL INDUCTION 12 27 0.0001395 0.00236
275 HIPPO SIGNALING 12 27 0.0001395 0.00236
276 RNA STABILIZATION 13 31 0.000152 0.002544
277 CARDIAC MUSCLE CELL DIFFERENTIATION 23 74 0.0001517 0.002544
278 REGULATION OF NEURON PROJECTION REGENERATION 10 20 0.0001517 0.002544
279 POSITIVE REGULATION OF MUSCLE TISSUE DEVELOPMENT 19 56 0.0001552 0.002589
280 SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 75 352 0.0001583 0.002621
281 REGULATION OF PROTEIN COMPLEX ASSEMBLY 79 375 0.0001579 0.002621
282 ENDOCRINE SYSTEM DEVELOPMENT 33 123 0.0001643 0.00271
283 REGULATION OF CYTOPLASMIC TRANSPORT 97 481 0.0001683 0.002738
284 CELLULAR RESPONSE TO STEROID HORMONE STIMULUS 51 218 0.0001679 0.002738
285 REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 51 218 0.0001679 0.002738
286 REGULATION OF GTPASE ACTIVITY 129 673 0.0001676 0.002738
287 ACTIVATION OF PROTEIN KINASE ACTIVITY 62 279 0.0001708 0.002769
288 REGULATION OF GENE SILENCING 18 52 0.0001721 0.00278
289 DNA TEMPLATED TRANSCRIPTION INITIATION 48 202 0.0001738 0.002798
290 CENTRAL NERVOUS SYSTEM NEURON DEVELOPMENT 22 70 0.0001749 0.002807
291 WOUND HEALING 95 470 0.0001795 0.00287
292 POSITIVE REGULATION OF MRNA 3 END PROCESSING 9 17 0.0001877 0.002991
293 POSITIVE REGULATION OF PROTEIN LOCALIZATION TO NUCLEUS 34 129 0.0001912 0.003036
294 SOMATIC STEM CELL POPULATION MAINTENANCE 21 66 0.0002009 0.00318
295 ADULT LOCOMOTORY BEHAVIOR 24 80 0.0002023 0.003184
296 EYE DEVELOPMENT 70 326 0.0002026 0.003184
297 REGULATION OF MRNA 3 END PROCESSING 12 28 0.0002128 0.00333
298 POSITIVE REGULATION OF TRANSPORT 171 936 0.0002133 0.00333
299 POSITIVE REGULATION OF HYDROLASE ACTIVITY 166 905 0.0002153 0.003345
300 ENDOCRINE PANCREAS DEVELOPMENT 15 40 0.0002157 0.003345
301 MEMBRANE DEPOLARIZATION DURING CARDIAC MUSCLE CELL ACTION POTENTIAL 8 14 0.0002171 0.003345
302 NEGATIVE REGULATION OF MUSCLE HYPERTROPHY 8 14 0.0002171 0.003345
303 REGENERATION 40 161 0.0002179 0.003346
304 PROTEIN UBIQUITINATION 121 629 0.0002268 0.003471
305 SOMITOGENESIS 20 62 0.0002297 0.003505
306 REGULATION OF GLUCOSE TRANSPORT 28 100 0.0002306 0.003507
307 NEPHRON DEVELOPMENT 31 115 0.0002329 0.00353
308 NEGATIVE REGULATION OF DEVELOPMENTAL PROCESS 149 801 0.0002338 0.003533
309 RESPONSE TO MECHANICAL STIMULUS 49 210 0.000238 0.003584
310 REGULATION OF MITOTIC CELL CYCLE 94 468 0.0002436 0.003656
311 MUSCLE ORGAN DEVELOPMENT 61 277 0.0002485 0.003718
312 CARDIAC CELL DEVELOPMENT 17 49 0.0002509 0.003741
313 REGULATION OF CHROMATIN SILENCING 10 21 0.0002529 0.00376
314 NUCLEUS ORGANIZATION 35 136 0.0002559 0.003793
315 CHROMOSOME SEGREGATION 60 272 0.0002652 0.003917
316 POSITIVE REGULATION OF PROTEIN SERINE THREONINE KINASE ACTIVITY 63 289 0.0002667 0.003927
317 CELLULAR RESPONSE TO NITROGEN COMPOUND 100 505 0.0002688 0.003946
318 REGULATION OF SMALL GTPASE MEDIATED SIGNAL TRANSDUCTION 61 278 0.0002752 0.004014
319 MODIFICATION BY SYMBIONT OF HOST MORPHOLOGY OR PHYSIOLOGY 16 45 0.0002746 0.004014
320 SISTER CHROMATID COHESION 30 111 0.0002773 0.004033
321 REGULATION OF CELL CYCLE G1 S PHASE TRANSITION 37 147 0.0002797 0.004054
322 SENSORY ORGAN MORPHOGENESIS 54 239 0.0002814 0.004066
323 REGULATION OF BODY FLUID LEVELS 100 506 0.0002893 0.004168
324 SINGLE ORGANISM CELLULAR LOCALIZATION 164 898 0.0002904 0.004171
325 REGULATION OF BMP SIGNALING PATHWAY 23 77 0.000292 0.004181
326 CELLULAR RESPONSE TO EPIDERMAL GROWTH FACTOR STIMULUS 11 25 0.0002953 0.004215
327 SINGLE ORGANISM CELL ADHESION 92 459 0.0003035 0.004318
328 MEMBRANE ORGANIZATION 164 899 0.0003066 0.004349
329 PALLIUM DEVELOPMENT 38 153 0.0003111 0.004389
330 REGULATION OF MUSCLE HYPERTROPHY 14 37 0.0003122 0.004389
331 PATTERN SPECIFICATION PROCESS 85 418 0.0003122 0.004389
332 REGULATION OF TRANSMEMBRANE RECEPTOR PROTEIN SERINE THREONINE KINASE SIGNALING PATHWAY 48 207 0.0003191 0.004472
333 POSITIVE REGULATION OF EMBRYONIC DEVELOPMENT 13 33 0.0003204 0.004478
334 PEPTIDYL SERINE MODIFICATION 37 148 0.0003228 0.004484
335 REGULATION OF ORGANELLE ASSEMBLY 37 148 0.0003228 0.004484
336 MAMMARY GLAND DEVELOPMENT 31 117 0.0003245 0.004494
337 REGULATION OF SKELETAL MUSCLE TISSUE DEVELOPMENT 17 50 0.0003304 0.004538
338 CELL ACTIVATION 110 568 0.0003306 0.004538
339 POSITIVE REGULATION OF STEM CELL DIFFERENTIATION 17 50 0.0003304 0.004538
340 CELLULAR RESPONSE TO OXYGEN LEVELS 36 143 0.0003343 0.004574
341 PANCREAS DEVELOPMENT 22 73 0.0003413 0.004644
342 HIPPOCAMPUS DEVELOPMENT 22 73 0.0003413 0.004644
343 NEGATIVE REGULATION OF CELL DEVELOPMENT 65 303 0.000344 0.004667
344 RENAL TUBULE DEVELOPMENT 23 78 0.0003593 0.004846
345 SOMITE DEVELOPMENT 23 78 0.0003593 0.004846
346 MUSCLE CELL DEVELOPMENT 33 128 0.0003653 0.004912
347 POST GOLGI VESICLE MEDIATED TRANSPORT 24 83 0.0003731 0.005003
348 PLASMA MEMBRANE ORGANIZATION 47 203 0.0003797 0.005063
349 REGULATION OF CELL GROWTH 80 391 0.0003787 0.005063
350 NEGATIVE REGULATION OF MUSCLE CELL DIFFERENTIATION 18 55 0.000381 0.005066
351 NEGATIVE REGULATION OF CELL DEATH 159 872 0.000385 0.005104
352 POSITIVE REGULATION OF EPITHELIAL CELL MIGRATION 28 103 0.0003932 0.005194
353 ANGIOGENESIS 63 293 0.0003941 0.005194
354 POSITIVE REGULATION OF DNA BINDING 15 42 0.0004005 0.005249
355 GENE SILENCING BY RNA 35 139 0.0003996 0.005249
356 UROGENITAL SYSTEM DEVELOPMENT 64 299 0.0004049 0.005292
357 REGULATION OF SODIUM ION TRANSMEMBRANE TRANSPORTER ACTIVITY 14 38 0.0004304 0.00561
358 POSITIVE REGULATION OF SKELETAL MUSCLE TISSUE DEVELOPMENT 11 26 0.0004467 0.005806
359 REGULATION OF AUTOPHAGY 55 249 0.0004505 0.005839
360 NEGATIVE REGULATION OF MITOTIC CELL CYCLE 46 199 0.000452 0.005842
361 REGULATION OF DENDRITIC SPINE MORPHOGENESIS 12 30 0.0004597 0.005926
362 BONE DEVELOPMENT 38 156 0.0004691 0.005974
363 REGULATION OF RAC PROTEIN SIGNAL TRANSDUCTION 7 12 0.0004679 0.005974
364 ACTION POTENTIAL 26 94 0.0004669 0.005974
365 CELL FATE COMMITMENT 51 227 0.0004699 0.005974
366 POSITIVE REGULATION OF PROTEIN IMPORT 28 104 0.0004664 0.005974
367 EPITHELIAL TO MESENCHYMAL TRANSITION 18 56 0.000488 0.00617
368 REGULATION OF DENDRITIC SPINE DEVELOPMENT 18 56 0.000488 0.00617
369 RESPONSE TO ENDOPLASMIC RETICULUM STRESS 52 233 0.0004914 0.006197
370 KIDNEY EPITHELIUM DEVELOPMENT 32 125 0.0005083 0.006392
371 POSITIVE REGULATION OF CELL DEATH 115 605 0.0005118 0.006419
372 ARTERY DEVELOPMENT 22 75 0.0005178 0.006476
373 VESICLE MEDIATED TRANSPORT 216 1239 0.0005246 0.006544
374 NEGATIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT 57 262 0.0005353 0.006642
375 REGULATION OF HORMONE SECRETION 57 262 0.0005353 0.006642
376 EAR DEVELOPMENT 45 195 0.000538 0.006658
377 REGULATION OF CHROMOSOME SEGREGATION 24 85 0.0005478 0.006725
378 REGULATION OF CELL MIGRATION INVOLVED IN SPROUTING ANGIOGENESIS 9 19 0.0005454 0.006725
379 POSITIVE REGULATION OF CELL CYCLE ARREST 24 85 0.0005478 0.006725
380 METENCEPHALON DEVELOPMENT 27 100 0.0005561 0.006744
381 COGNITION 55 251 0.0005529 0.006744
382 REGULATION OF CELL MATRIX ADHESION 25 90 0.0005549 0.006744
383 ODONTOGENESIS 28 105 0.0005513 0.006744
384 ACTIVATION OF MAPKK ACTIVITY 17 52 0.0005565 0.006744
385 POSITIVE REGULATION OF WNT SIGNALING PATHWAY 37 152 0.0005606 0.006776
386 HOMEOSTATIC PROCESS 231 1337 0.0005666 0.00683
387 REGULATION OF GENE EXPRESSION EPIGENETIC 51 229 0.0005824 0.007003
388 GLANDULAR EPITHELIAL CELL DIFFERENTIATION 14 39 0.0005847 0.007012
389 POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION 64 303 0.0005867 0.007018
390 NEGATIVE REGULATION OF LOCOMOTION 57 263 0.0005909 0.00705
391 PLATELET ACTIVATION 35 142 0.0006107 0.007268
392 FEMALE SEX DIFFERENTIATION 30 116 0.0006239 0.007406
393 RHYTHMIC PROCESS 63 298 0.0006289 0.007446
394 REGULATION OF CELLULAR RESPONSE TO HEAT 22 76 0.0006325 0.00747
395 NUCLEAR ENVELOPE ORGANIZATION 23 81 0.0006492 0.007647
396 NEGATIVE REGULATION OF RESPONSE TO STIMULUS 234 1360 0.0006612 0.00777
397 SIGNAL TRANSDUCTION IN RESPONSE TO DNA DAMAGE 26 96 0.000663 0.00777
398 CELLULAR RESPONSE TO ACID CHEMICAL 41 175 0.0006731 0.007869
399 REGULATION OF JNK CASCADE 38 159 0.0006948 0.008102
400 REGULATION OF INTRACELLULAR PROTEIN TRANSPORT 77 381 0.0007022 0.008169
401 POSITIVE REGULATION OF ENDOTHELIAL CELL MIGRATION 20 67 0.0007144 0.008248
402 MESONEPHRIC TUBULE MORPHOGENESIS 17 53 0.0007125 0.008248
403 RNA DESTABILIZATION 8 16 0.0007137 0.008248
404 ENDOTHELIAL CELL DIFFERENTIATION 21 72 0.0007462 0.008573
405 RESPONSE TO AMINO ACID 29 112 0.0007462 0.008573
406 REGULATION OF TRANSPORTER ACTIVITY 45 198 0.0007586 0.008694
407 POSITIVE REGULATION OF NEURON PROJECTION DEVELOPMENT 51 232 0.0007964 0.009105
408 CARDIAC CHAMBER DEVELOPMENT 35 144 0.0008013 0.009138
409 NEGATIVE REGULATION OF CELL COMMUNICATION 207 1192 0.0008354 0.009504
410 REGULATION OF RNA STABILITY 34 139 0.0008376 0.009506
411 MYOBLAST FUSION 9 20 0.0008675 0.009821
412 INTRACELLULAR PROTEIN TRANSPORT 142 781 0.0008708 0.009835
413 MULTI ORGANISM TRANSPORT 20 68 0.0008791 0.00988
414 MULTI ORGANISM LOCALIZATION 20 68 0.0008791 0.00988
415 REGULATION OF I KAPPAB KINASE NF KAPPAB SIGNALING 51 233 0.0008818 0.009887
NumGOOverlapSizeP ValueAdj. P Value
1 ENZYME BINDING 393 1737 1.721e-23 1.599e-20
2 MACROMOLECULAR COMPLEX BINDING 292 1399 9.008e-13 4.184e-10
3 RNA BINDING 323 1598 3.338e-12 1.034e-09
4 POLY A RNA BINDING 248 1170 1.087e-11 2.524e-09
5 RIBONUCLEOTIDE BINDING 362 1860 2.492e-11 4.629e-09
6 ADENYL NUCLEOTIDE BINDING 303 1514 5.562e-11 8.612e-09
7 KINASE BINDING 144 606 1.082e-10 1.437e-08
8 CYTOSKELETAL PROTEIN BINDING 181 819 2.644e-10 3.07e-08
9 REGULATORY REGION NUCLEIC ACID BINDING 179 818 7.53e-10 7.772e-08
10 SEQUENCE SPECIFIC DNA BINDING 215 1037 2.109e-09 1.959e-07
11 CORE PROMOTER BINDING 48 152 3.139e-08 2.481e-06
12 PROTEIN KINASE ACTIVITY 141 640 3.205e-08 2.481e-06
13 TRANSFERASE ACTIVITY TRANSFERRING PHOSPHORUS CONTAINING GROUPS 201 992 4.627e-08 3.307e-06
14 KINASE ACTIVITY 175 842 5.897e-08 3.913e-06
15 RNA POLYMERASE II TRANSCRIPTION FACTOR ACTIVITY SEQUENCE SPECIFIC DNA BINDING 137 629 1.027e-07 6.015e-06
16 PROTEIN SERINE THREONINE KINASE ACTIVITY 104 445 1.036e-07 6.015e-06
17 RAN GTPASE BINDING 17 31 1.297e-07 7.088e-06
18 DOUBLE STRANDED DNA BINDING 159 764 2.201e-07 1.136e-05
19 CHROMATIN BINDING 100 435 4.145e-07 2.027e-05
20 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 80 328 4.939e-07 2.294e-05
21 PROTEIN COMPLEX BINDING 185 935 8.614e-07 3.637e-05
22 TRANSCRIPTION FACTOR ACTIVITY PROTEIN BINDING 126 588 8.293e-07 3.637e-05
23 PROTEIN DOMAIN SPECIFIC BINDING 132 624 9.514e-07 3.843e-05
24 TRANSCRIPTION FACTOR BINDING 114 524 1.272e-06 4.924e-05
25 ZINC ION BINDING 219 1155 2.183e-06 8.113e-05
26 CORE PROMOTER PROXIMAL REGION DNA BINDING 85 371 3.439e-06 0.0001229
27 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II CORE PROMOTER PROXIMAL REGION SEQUENCE SPECIFIC BINDING 57 226 7.081e-06 0.0002437
28 TRANSCRIPTIONAL ACTIVATOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 73 315 1.078e-05 0.0003578
29 CALMODULIN BINDING 47 179 1.427e-05 0.0004573
30 UBIQUITIN LIKE PROTEIN LIGASE BINDING 63 264 1.618e-05 0.0005009
31 ACTIN BINDING 86 393 1.965e-05 0.0005888
32 HEAT SHOCK PROTEIN BINDING 28 89 2.385e-05 0.0006924
33 NUCLEIC ACID BINDING TRANSCRIPTION FACTOR ACTIVITY 219 1199 2.883e-05 0.0008117
34 STEROID HORMONE RECEPTOR BINDING 26 81 3.119e-05 0.0008522
35 NUCLEOCYTOPLASMIC TRANSPORTER ACTIVITY 12 24 3.281e-05 0.0008707
36 PROTEIN PHOSPHATASE BINDING 34 120 4.016e-05 0.001033
37 PROTEIN C TERMINUS BINDING 47 186 4.115e-05 0.001033
38 PROTEIN TRANSPORTER ACTIVITY 29 99 7.484e-05 0.00183
39 UBIQUITIN LIKE PROTEIN TRANSFERASE ACTIVITY 88 420 8.446e-05 0.001941
40 RIBONUCLEOPROTEIN COMPLEX BINDING 28 95 8.775e-05 0.001941
41 PDZ DOMAIN BINDING 27 90 8.34e-05 0.001941
42 GTPASE BINDING 66 295 8.701e-05 0.001941
43 HISTONE DEACETYLASE BINDING 30 105 9.408e-05 0.002033
44 HSP70 PROTEIN BINDING 13 30 0.0001013 0.00214
45 MAGNESIUM ION BINDING 48 199 0.0001185 0.002447
46 TRANSCRIPTIONAL REPRESSOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION REGULATORY REGION SEQUENCE SPECIFIC BINDING 42 168 0.0001327 0.00268
47 TRANSITION METAL ION BINDING 245 1400 0.0001762 0.003482
48 PHOSPHATASE BINDING 40 162 0.0002504 0.004846
49 PROTEIN KINASE C BINDING 17 50 0.0003304 0.006264
50 TRANSCRIPTION FACTOR ACTIVITY RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 34 133 0.0003557 0.006608
51 MRNA BINDING 38 155 0.0004099 0.007467
52 IDENTICAL PROTEIN BINDING 212 1209 0.0004299 0.007681
53 TRANSCRIPTION COREPRESSOR ACTIVITY 50 221 0.0004479 0.007851
54 RNA POLYMERASE II TRANSCRIPTION FACTOR BINDING 28 104 0.0004664 0.008024
55 PROTEIN DIMERIZATION ACTIVITY 202 1149 0.0005101 0.008313
56 PHOSPHATIDYLINOSITOL BINDING 46 200 0.0005078 0.008313
57 MOLECULAR FUNCTION REGULATOR 234 1353 0.000493 0.008313
58 CHROMATIN DNA BINDING 23 80 0.0005356 0.008579
59 HORMONE RECEPTOR BINDING 40 168 0.0005534 0.008714
NumGOOverlapSizeP ValueAdj. P Value
1 CELL JUNCTION 265 1151 6.626e-17 3.87e-14
2 CELL CELL JUNCTION 102 383 8.047e-11 2.35e-08
3 CELL PROJECTION 336 1786 7.673e-09 1.494e-06
4 ANCHORING JUNCTION 115 489 1.535e-08 1.685e-06
5 NUCLEAR PORE 31 77 1.685e-08 1.685e-06
6 MEMBRANE REGION 227 1134 1.731e-08 1.685e-06
7 NUCLEAR ENVELOPE 101 416 2.107e-08 1.758e-06
8 MICROTUBULE CYTOSKELETON 215 1068 2.647e-08 1.932e-06
9 CYTOSKELETON 361 1967 3.422e-08 2.221e-06
10 APICAL JUNCTION COMPLEX 42 128 6.683e-08 3.903e-06
11 PLASMA MEMBRANE REGION 189 929 8.758e-08 4.65e-06
12 CELL LEADING EDGE 85 350 2.677e-07 1.303e-05
13 NEURON PART 241 1265 4.474e-07 2.01e-05
14 CYTOSKELETAL PART 268 1436 5.949e-07 2.481e-05
15 GOLGI APPARATUS 269 1445 7.024e-07 2.564e-05
16 NUCLEOLUS 171 848 6.602e-07 2.564e-05
17 I BAND 38 121 9.614e-07 3.303e-05
18 SYNAPSE 154 754 1.102e-06 3.575e-05
19 TRANSFERASE COMPLEX 144 703 2.08e-06 5.521e-05
20 PCG PROTEIN COMPLEX 19 43 1.846e-06 5.521e-05
21 NUCLEOPLASM PART 145 708 1.936e-06 5.521e-05
22 NUCLEAR MEMBRANE 69 280 1.988e-06 5.521e-05
23 NEURON PROJECTION 183 942 3.324e-06 8.44e-05
24 CHROMOSOME 172 880 4.52e-06 0.00011
25 CELL SUBSTRATE JUNCTION 88 398 1.041e-05 0.0002431
26 ACTIN CYTOSKELETON 96 444 1.117e-05 0.0002509
27 VACUOLE 218 1180 1.417e-05 0.0003012
28 CATALYTIC COMPLEX 195 1038 1.444e-05 0.0003012
29 APICAL PART OF CELL 79 361 4.192e-05 0.0008443
30 PERINUCLEAR REGION OF CYTOPLASM 127 642 4.518e-05 0.0008795
31 EARLY ENDOSOME 68 301 4.997e-05 0.0009413
32 SYNAPSE PART 120 610 9.261e-05 0.00166
33 ENDOSOME 150 793 9.951e-05 0.00166
34 PLASMA MEMBRANE RAFT 26 86 9.719e-05 0.00166
35 VACUOLAR MEMBRANE 116 587 9.921e-05 0.00166
36 GOLGI APPARATUS PART 166 893 0.0001089 0.001767
37 CHROMATIN 91 441 0.0001147 0.00181
38 SOMATODENDRITIC COMPARTMENT 126 650 0.0001215 0.001867
39 SPINDLE 64 289 0.0001504 0.002251
40 MICROTUBULE 84 405 0.0001725 0.002519
41 NUCLEAR CHROMATIN 64 291 0.0001847 0.00263
42 APICAL PLASMA MEMBRANE 64 292 0.0002044 0.002842
43 TRANSCRIPTION FACTOR COMPLEX 65 298 0.0002115 0.002873
44 RUFFLE 39 156 0.0002261 0.003001
45 T TUBULE 16 45 0.0002746 0.003564
46 CELL CELL CONTACT ZONE 20 64 0.0003691 0.004686
47 MITOTIC SPINDLE 18 55 0.000381 0.004735
48 VACUOLAR PART 130 694 0.0004269 0.005195
49 GOLGI MEMBRANE 131 703 0.0005056 0.005906
50 CELL PROJECTION PART 170 946 0.0005012 0.005906
51 ENDOPLASMIC RETICULUM LUMEN 46 201 0.0005697 0.006523
52 CHROMOSOME CENTROMERIC REGION 41 174 0.0005955 0.006688
53 VESICLE MEMBRANE 99 512 0.0006751 0.007438
54 CLATHRIN COAT OF COATED PIT 8 16 0.0007137 0.007719
55 ENDOPLASMIC RETICULUM 275 1631 0.0008137 0.00864
56 EARLY ENDOSOME MEMBRANE 29 113 0.0008701 0.009074
57 CYTOPLASMIC STRESS GRANULE 12 32 0.0009128 0.009352

Over-represented Pathway

NumPathwayPathviewOverlapSizeP ValueAdj. P Value
1 Focal_adhesion_hsa04510 59 199 1.223e-08 6.361e-07
2 Tight_junction_hsa04530 48 170 1.305e-06 2.283e-05
3 mTOR_signaling_pathway_hsa04150 44 151 1.406e-06 2.283e-05
4 MAPK_signaling_pathway_hsa04010 72 295 1.756e-06 2.283e-05
5 Cell_cycle_hsa04110 37 124 5.129e-06 5.334e-05
6 Rap1_signaling_pathway_hsa04015 53 206 7.936e-06 5.867e-05
7 Wnt_signaling_pathway_hsa04310 41 146 8.67e-06 5.867e-05
8 PI3K_Akt_signaling_pathway_hsa04151 80 352 9.027e-06 5.867e-05
9 Hippo_signaling_pathway_hsa04390 42 154 1.488e-05 8.599e-05
10 Signaling_pathways_regulating_pluripotency_of_stem_cells_hsa04550 38 139 3.505e-05 0.0001823
11 FoxO_signaling_pathway_hsa04068 36 132 5.871e-05 0.0002617
12 cGMP_PKG_signaling_pathway_hsa04022 42 163 6.373e-05 0.0002617
13 Ras_signaling_pathway_hsa04014 55 232 6.541e-05 0.0002617
14 cAMP_signaling_pathway_hsa04024 48 198 0.000104 0.0003863
15 Apelin_signaling_pathway_hsa04371 36 137 0.0001344 0.0004661
16 ErbB_signaling_pathway_hsa04012 25 85 0.0002126 0.0006909
17 Adherens_junction_hsa04520 22 72 0.0002748 0.0008405
18 Calcium_signaling_pathway_hsa04020 43 182 0.0004186 0.001209
19 Cellular_senescence_hsa04218 38 160 0.0007889 0.002159
20 Phospholipase_D_signaling_pathway_hsa04072 35 146 0.001042 0.00271
21 Regulation_of_actin_cytoskeleton_hsa04810 45 208 0.002177 0.005198
22 Gap_junction_hsa04540 23 88 0.002199 0.005198
23 AMPK_signaling_pathway_hsa04152 29 121 0.002688 0.006074
24 HIF_1_signaling_pathway_hsa04066 25 100 0.002804 0.006074
25 Cell_adhesion_molecules_.CAMs._hsa04514 33 145 0.003488 0.007256
26 Hippo_signaling_pathway_multiple_species_hsa04392 10 29 0.004896 0.009792
27 VEGF_signaling_pathway_hsa04370 16 59 0.006675 0.01286
28 Hedgehog_signaling_pathway_hsa04340 13 47 0.0116 0.02154
29 Sphingolipid_signaling_pathway_hsa04071 26 118 0.01339 0.02401
30 Oocyte_meiosis_hsa04114 27 124 0.01387 0.02405
31 Endocytosis_hsa04144 46 244 0.02494 0.04184
32 TNF_signaling_pathway_hsa04668 23 108 0.02788 0.0453
33 ECM_receptor_interaction_hsa04512 18 82 0.03653 0.05757
34 Phosphatidylinositol_signaling_system_hsa04070 20 99 0.06186 0.09461
35 NF_kappa_B_signaling_pathway_hsa04064 19 95 0.07326 0.1088
36 TGF_beta_signaling_pathway_hsa04350 17 84 0.07933 0.1146
37 Autophagy_animal_hsa04140 24 128 0.08975 0.1261
38 p53_signaling_pathway_hsa04115 14 68 0.09334 0.1277
39 Ferroptosis_hsa04216 9 40 0.1036 0.1382
40 Lysosome_hsa04142 22 123 0.1459 0.1897
41 Apoptosis_hsa04210 24 138 0.1662 0.2108
42 Cytokine_cytokine_receptor_interaction_hsa04060 43 270 0.2253 0.279
43 Notch_signaling_pathway_hsa04330 9 48 0.233 0.2818
44 Apoptosis_multiple_species_hsa04215 6 33 0.3225 0.3812
45 Jak_STAT_signaling_pathway_hsa04630 25 162 0.3547 0.4099
46 ABC_transporters_hsa02010 6 45 0.6288 0.7109
47 Autophagy_other_hsa04136 4 32 0.6833 0.756
48 Mitophagy_animal_hsa04137 8 65 0.7195 0.7795
49 Peroxisome_hsa04146 10 83 0.7562 0.7869
50 Phagosome_hsa04145 19 152 0.7566 0.7869
51 Necroptosis_hsa04217 19 164 0.8578 0.8746
52 Neuroactive_ligand_receptor_interaction_hsa04080 33 278 0.8857 0.8857

Quest ID: f908baab7b830f83544a8069683321c4