miRNA	gene	miRNA_log2FC	miRNA_pvalue	gene_log2FC	gene_pvalue	interactions	correlation_beta	correlation_pvalue	PMID	evidence	outcome	cancer
hsa-miR-16-5p	ABHD2	0.749619098384047	4.11649450706988e-06	-0.739964531699677	0.000588994320504455	miRNAWalker2_validate	-0.226305555437727	0.000205482898011766		NA	NA	NA
hsa-miR-16-5p	ABR	0.749619098384047	4.11649450706988e-06	-0.420721071442296	0.00324766348407776	mirMAP	-0.148680063925291	0.000227686720973536		NA	NA	NA
hsa-miR-16-5p	ABTB2	0.749619098384047	4.11649450706988e-06	0.660554809173039	0.00532807988256168	MirTarget	-0.257265128101859	0.000121855904088791		NA	NA	NA
hsa-miR-16-5p	ACSBG1	0.749619098384047	4.11649450706988e-06	-2.22330053295797	6.58207489497956e-10	MirTarget	-0.269251034497843	0.0095177452298542		NA	NA	NA
hsa-miR-16-5p	ACTN1	0.749619098384047	4.11649450706988e-06	-0.110047045821892	0.507390369482496	miRNAWalker2_validate	-0.196080272483675	2.55230429566812e-05		NA	NA	NA
hsa-miR-16-5p	ADAMTS18	0.749619098384047	4.11649450706988e-06	1.33973507171443	0.00246715470615367	miRNATAP	-0.333331703147485	0.00801149700599979		NA	NA	NA
hsa-miR-16-5p	ADAMTS5	0.749619098384047	4.11649450706988e-06	-0.154253020317757	0.635472813443512	miRNATAP	-0.230768317208971	0.0121343113777713		NA	NA	NA
hsa-miR-16-5p	ADAMTSL3	0.749619098384047	4.11649450706988e-06	-3.14977760857486	5.93956173009134e-19	MirTarget	-0.276550186262874	0.00804740847287741		NA	NA	NA
hsa-miR-193b-3p	ADAMTSL3	1.10444771306846	0.000822888533401377	-3.14977760857486	5.93956173009134e-19	MirTarget	-0.197451355787451	0.00010758171104455		NA	NA	NA
hsa-miR-16-5p	ADCY2	0.749619098384047	4.11649450706988e-06	-1.12306124221749	0.0147274014149145	mirMAP	-0.30980382546084	0.0177512371734785		NA	NA	NA
hsa-miR-16-5p	ADCY5	0.749619098384047	4.11649450706988e-06	-1.40739822429482	0.00306046416195092	MirTarget;miRNATAP	-0.429487797384091	0.00143530222039218		NA	NA	NA
hsa-miR-193b-3p	ADCY9	1.10444771306846	0.000822888533401377	-1.41035089915206	4.71373266738884e-11	miRNAWalker2_validate	-0.161651699517894	7.34857235472482e-08		NA	NA	NA
hsa-miR-16-5p	AFF4	0.749619098384047	4.11649450706988e-06	-0.152661809298122	0.224770903585219	MirTarget;miRNATAP	-0.10779295138001	0.002324592142496		NA	NA	NA
hsa-miR-16-5p	AHNAK2	0.749619098384047	4.11649450706988e-06	1.25636169830546	0.00480956731915303	miRNAWalker2_validate	-0.470678745041135	0.000187947910903759		NA	NA	NA
hsa-miR-16-5p	AKAP13	0.749619098384047	4.11649450706988e-06	-1.20127325864564	1.58040431622387e-11	miRNAWalker2_validate	-0.108064089347792	0.0362088597972343		NA	NA	NA
hsa-miR-193b-3p	AKAP13	1.10444771306846	0.000822888533401377	-1.20127325864564	1.58040431622387e-11	miRNAWalker2_validate	-0.114272835766917	5.26681445128801e-06		NA	NA	NA
hsa-miR-16-5p	AKT3	0.749619098384047	4.11649450706988e-06	-1.44031241124732	2.576504600149e-09	miRNAWalker2_validate;miRTarBase;miRNATAP	-0.269698520974258	9.94440318719177e-05		NA	NA	NA
hsa-miR-193b-3p	ALDH1A2	1.10444771306846	0.000822888533401377	-3.09249622169711	5.66868640549027e-10	miRNAWalker2_validate	-0.147796373049858	0.0366170142253523		NA	NA	NA
hsa-miR-16-5p	AMOTL1	0.749619098384047	4.11649450706988e-06	-2.0405434313863	1.66077976637358e-18	MirTarget;miRNATAP	-0.236007753705047	0.000538462798530914		NA	NA	NA
hsa-miR-16-5p	AMPD1	0.749619098384047	4.11649450706988e-06	0.109877479775896	0.820885050080268	miRNAWalker2_validate	-0.317050856981326	0.0209549613346606		NA	NA	NA
hsa-miR-16-5p	ANK2	0.749619098384047	4.11649450706988e-06	-1.33511253841397	1.59570434099066e-05	MirTarget;miRNATAP	-0.190378943402157	0.0313018172100131		NA	NA	NA
hsa-miR-16-5p	ANKS1A	0.749619098384047	4.11649450706988e-06	-1.10905964008158	6.46785256415143e-17	MirTarget	-0.169094855074204	1.15084291583763e-05		NA	NA	NA
hsa-miR-193b-3p	APCDD1	1.10444771306846	0.000822888533401377	-1.23501619151485	1.47653912408707e-06	miRNAWalker2_validate	-0.148894407822851	3.19465484242216e-05		NA	NA	NA
hsa-miR-16-5p	APLN	0.749619098384047	4.11649450706988e-06	-2.01978623826271	1.79053400840074e-09	MirTarget;miRNATAP	-0.201541760568144	0.0374656500616432		NA	NA	NA
hsa-miR-16-5p	APP	0.749619098384047	4.11649450706988e-06	-0.38170965151363	0.0145852282320034	miRNAWalker2_validate;miRNATAP	-0.18657589157845	2.18717789416064e-05		NA	NA	NA
hsa-miR-16-5p	AR	0.749619098384047	4.11649450706988e-06	-1.81828073021777	5.78986294503712e-05	mirMAP;miRNATAP	-0.36075915760998	0.00511979001922129		NA	NA	NA
hsa-miR-16-5p	ARHGAP20	0.749619098384047	4.11649450706988e-06	-1.0567409776775	0.00416916469146332	MirTarget;miRNATAP	-0.292550361091863	0.0051859370820567		NA	NA	NA
hsa-miR-16-5p	ARHGAP32	0.749619098384047	4.11649450706988e-06	0.451623462340779	0.0145616158637595	MirTarget	-0.1966418648025	0.000162179236548139		NA	NA	NA
hsa-miR-16-5p	ARHGEF12	0.749619098384047	4.11649450706988e-06	-0.37058495546586	0.0051319052872721	MirTarget	-0.163051270602082	1.18046884570495e-05		NA	NA	NA
hsa-miR-16-5p	ARHGEF9	0.749619098384047	4.11649450706988e-06	-0.323827554229584	0.0224529248225446	miRNATAP	-0.10624400396877	0.00805467849033042		NA	NA	NA
hsa-miR-16-5p	ARL10	0.749619098384047	4.11649450706988e-06	-0.255650987144674	0.31667685764498	miRNAWalker2_validate	-0.244220545543523	0.000692712366704652		NA	NA	NA
hsa-miR-16-5p	ARNT2	0.749619098384047	4.11649450706988e-06	-1.45715195726702	2.85732204114713e-05	mirMAP	-0.262394141895777	0.00825616551250813		NA	NA	NA
hsa-miR-16-5p	ASH1L	0.749619098384047	4.11649450706988e-06	0.139976924852056	0.332499833679304	miRNAWalker2_validate;MirTarget;miRNATAP	-0.118218173379297	0.00368018450231771		NA	NA	NA
hsa-miR-16-5p	ASXL2	0.749619098384047	4.11649450706988e-06	-0.304319336802245	0.128373105979599	miRNAWalker2_validate	-0.176861444297228	0.00174170701681055		NA	NA	NA
hsa-miR-16-5p	ATF7	0.749619098384047	4.11649450706988e-06	-0.290321701668191	0.00532552428973049	miRNAWalker2_validate	-0.108659912788533	0.000208107653763422		NA	NA	NA
hsa-miR-193b-3p	ATOH8	1.10444771306846	0.000822888533401377	-2.72103847998983	7.1991717625812e-09	miRNAWalker2_validate	-0.254180068684953	0.000120935427560579		NA	NA	NA
hsa-miR-193b-3p	ATP1A1	1.10444771306846	0.000822888533401377	-0.499146463984982	0.00344488026440897	miRNAWalker2_validate	-0.108679710734283	3.93600377478453e-06		NA	NA	NA
hsa-miR-16-5p	ATP7A	0.749619098384047	4.11649450706988e-06	-0.0892141784399554	0.53504609097303	MirTarget	-0.118569217719875	0.00342544156064224		NA	NA	NA
hsa-miR-16-5p	ATP8A2	0.749619098384047	4.11649450706988e-06	-2.00386619271038	3.49925438832799e-06	miRNAWalker2_validate	-0.261725518136173	0.0343249718902138		NA	NA	NA
hsa-miR-16-5p	ATXN1L	0.749619098384047	4.11649450706988e-06	-0.657553672381893	2.9442946703612e-08	miRNATAP	-0.159102778520608	2.27091743566009e-06		NA	NA	NA
hsa-miR-16-5p	AXIN2	0.749619098384047	4.11649450706988e-06	-1.4952232670323	9.5322330602006e-08	miRNAWalker2_validate;miRTarBase;MirTarget;miRNATAP	-0.200486504280819	0.0126683953593233		NA	NA	NA
hsa-miR-16-5p	BACE1	0.749619098384047	4.11649450706988e-06	-0.798549443120606	3.32363960615768e-07	miRNATAP	-0.28361735603371	1.0654942418142e-10		NA	NA	NA
hsa-miR-16-5p	BACH2	0.749619098384047	4.11649450706988e-06	-0.986923106787666	6.05178258681954e-05	MirTarget;miRNATAP	-0.205681422178427	0.00331980123579326		NA	NA	NA
hsa-miR-16-5p	BAMBI	0.749619098384047	4.11649450706988e-06	-0.153427981324985	0.71189032443375	miRNAWalker2_validate	-0.334827118110581	0.00433371548349149		NA	NA	NA
hsa-miR-16-5p	BCL2L2	0.749619098384047	4.11649450706988e-06	-0.960980288876281	1.39491048132035e-14	MirTarget;miRNATAP	-0.10143432630875	0.00515756076128173		NA	NA	NA
hsa-miR-193b-3p	BHLHE41	1.10444771306846	0.000822888533401377	-1.4042924755583	6.57937501917133e-07	MirTarget	-0.139267484252954	0.000429041742384939		NA	NA	NA
hsa-miR-16-5p	BMX	0.749619098384047	4.11649450706988e-06	-3.65254511535376	2.60355895953583e-17	MirTarget;miRNATAP	-0.395965974098568	0.00174746730005418		NA	NA	NA
hsa-miR-16-5p	BNC2	0.749619098384047	4.11649450706988e-06	-1.11598908209254	1.25111407267166e-05	miRNAWalker2_validate	-0.314314821489466	1.43345429988143e-05		NA	NA	NA
hsa-miR-16-5p	BRPF3	0.749619098384047	4.11649450706988e-06	0.544154118348233	0.000298512241993249	miRNATAP	-0.116268145617614	0.00648421057700748		NA	NA	NA
hsa-miR-16-5p	BTBD19	0.749619098384047	4.11649450706988e-06	-0.45434171875947	0.0919153970821624	mirMAP	-0.29326382377652	0.00011292810310672		NA	NA	NA
hsa-miR-16-5p	BTRC	0.749619098384047	4.11649450706988e-06	0.0480417791180399	0.622827696093888	miRNAWalker2_validate;MirTarget;miRNATAP	-0.107405552913543	8.38188422898451e-05		NA	NA	NA
hsa-miR-16-5p	C15orf52	0.749619098384047	4.11649450706988e-06	-0.969272650717764	0.000287032456915159	mirMAP	-0.189510819617976	0.0127265543708191		NA	NA	NA
hsa-miR-193b-3p	C1QC	1.10444771306846	0.000822888533401377	-1.49390078003597	1.85904917085725e-07	MirTarget	-0.120811493729162	0.00269521686371511		NA	NA	NA
hsa-miR-193b-3p	C1QTNF2	1.10444771306846	0.000822888533401377	-2.2556154482988	2.97680803444235e-16	miRNAWalker2_validate	-0.124548212094048	0.0016435592569775		NA	NA	NA
hsa-miR-193b-3p	C5	1.10444771306846	0.000822888533401377	-1.05744717600087	0.0116349692105788	miRNAWalker2_validate	-0.24392036739578	2.59966147010135e-05		NA	NA	NA
hsa-miR-16-5p	CABIN1	0.749619098384047	4.11649450706988e-06	-0.208831146290723	0.118533887254733	miRNAWalker2_validate	-0.147095852263149	9.04048233042467e-05		NA	NA	NA
hsa-miR-193b-3p	CABLES1	1.10444771306846	0.000822888533401377	-1.218363249659	3.59723368979481e-06	mirMAP	-0.169187919254928	3.75495679457542e-06		NA	NA	NA
hsa-miR-16-5p	CACNA2D1	0.749619098384047	4.11649450706988e-06	-1.26894428990152	0.00468562348387855	miRNAWalker2_validate	-0.350453054379483	0.00592563587606449		NA	NA	NA
hsa-miR-16-5p	CADM1	0.749619098384047	4.11649450706988e-06	-1.97539534457883	2.23181309519858e-09	miRNAWalker2_validate;miRTarBase;miRNATAP	-0.230831407817494	0.0153214009677464		NA	NA	NA
hsa-miR-193b-3p	CADM1	1.10444771306846	0.000822888533401377	-1.97539534457883	2.23181309519858e-09	MirTarget	-0.275005346191019	2.20413555258771e-09		NA	NA	NA
hsa-miR-16-5p	CARD10	0.749619098384047	4.11649450706988e-06	0.34384156431803	0.145827135403965	miRNAWalker2_validate;MirTarget;miRNATAP	-0.324335582573567	9.78327312056735e-07		NA	NA	NA
hsa-miR-16-5p	CASR	0.749619098384047	4.11649450706988e-06	-0.850043341086663	0.200148493287663	miRNATAP	-0.437691156608939	0.0198527750127379		NA	NA	NA
hsa-miR-193b-3p	CBX7	1.10444771306846	0.000822888533401377	-1.83367364294193	5.2355108700289e-19	MirTarget;miRNATAP	-0.154020625366872	1.63911748808462e-07		NA	NA	NA
hsa-miR-16-5p	CCDC149	0.749619098384047	4.11649450706988e-06	0.092447984586606	0.525085194090483	MirTarget	-0.13457426481336	0.0010095951047211		NA	NA	NA
hsa-miR-193b-3p	CCDC28A	1.10444771306846	0.000822888533401377	-0.586904227244142	9.82722970100403e-06	miRNAWalker2_validate;MirTarget;miRNATAP	-0.107351198036055	4.2315920783098e-09		NA	NA	NA
hsa-miR-16-5p	CCND1	0.749619098384047	4.11649450706988e-06	-0.295767629587253	0.255400743295204	miRNAWalker2_validate;miRTarBase;MirTarget;miRNATAP	-0.371885624299403	3.21606546730418e-07	23991964;22922827;18483394	At the molecular level our results further revealed that cyclin D1 expression was negatively regulated by miR-16;CCND1 has been found to be a target of miR-15a and miR-16-1 through analysis of complementary sequences between microRNAs and CCND1 mRNA; Moreover the transcription of CCND1 is suppressed by miR-15a and miR-16-1 via direct binding to the CCND1 3'-untranslated region 3'-UTR;Truncation in CCND1 mRNA alters miR 16 1 regulation in mantle cell lymphoma; Furthermore we demonstrated that this truncation alters miR-16-1 binding sites and through the use of reporter constructs we were able to show that miR-16-1 regulates CCND1 mRNA expression; This study introduces the role of miR-16-1 in the regulation of CCND1 in MCL	;;	bladder cancer;sarcoma;lymphoma
hsa-miR-193b-3p	CCND1	1.10444771306846	0.000822888533401377	-0.295767629587253	0.255400743295204	miRNAWalker2_validate;miRTarBase;MirTarget	-0.147999411883792	3.70620495015026e-05	27071318;20655737;20304954;21893020;26129688	MicroRNA 193b inhibits the proliferation migration and invasion of gastric cancer cells via targeting cyclin D1; Further mechanism study indicated that CCND1 was a direct target of miR-193b in GC;CCND1 and ETS1 were revealed to be regulated by miR-193b directly;MicroRNA 193b represses cell proliferation and regulates cyclin D1 in melanoma; Overexpression of miR-193b in Malme-3M cells down-regulated CCND1 mRNA and protein by > or = 50%; A luciferase reporter assay confirmed that miR-193b directly regulates CCND1 by binding to the 3'untranslated region of CCND1 mRNA; These studies indicate that miR-193b represses cell proliferation and regulates CCND1 expression and suggest that dysregulation of miR-193b may play an important role in melanoma development;In a previous study we reported that miR-193b represses cell proliferation and regulates cyclin D1 in melanoma cells suggesting that miR-193b could act as a tumor suppressor;Epigenetically altered miR 193b targets cyclin D1 in prostate cancer; It has been suggested that miR-193b targets cyclin D1 in several malignancies; Here our aim was to determine if miR-193b targets cyclin D1 in prostate cancer; Furthermore the PC cell lines 22Rv1 and VCaP which express low levels of miR-193b and high levels of CCND1 showed significant growth retardation when treated with a CDK4/6 inhibitor; In contrast the inhibitor had no effect on the growth of PC-3 and DU145 cells with high miR-193b and low CCND1 expression; Taken together our data demonstrate that miR-193b targets cyclin D1 in prostate cancer	;;;;	gastric cancer;liver cancer;melanoma;melanoma;prostate cancer
hsa-miR-16-5p	CCND2	0.749619098384047	4.11649450706988e-06	-1.64140990579885	1.49666938681079e-12	miRNAWalker2_validate;miRNATAP	-0.135197503151631	0.0448488951166271		NA	NA	NA
hsa-miR-16-5p	CCNT1	0.749619098384047	4.11649450706988e-06	-0.346105873244542	0.145523684726295	miRNATAP	-0.167137565091649	0.0129677848328448		NA	NA	NA
hsa-miR-193b-3p	CD244	1.10444771306846	0.000822888533401377	-1.68150420216009	5.33961644023401e-09	MirTarget	-0.123214395279234	0.00242054282544472		NA	NA	NA
hsa-miR-193b-3p	CD47	1.10444771306846	0.000822888533401377	-0.760168496102592	2.3072703709992e-05	miRNATAP	-0.114093359857426	4.67673289960856e-06		NA	NA	NA
hsa-miR-16-5p	CD55	0.749619098384047	4.11649450706988e-06	-0.851395238667138	0.00258654256777557	miRNAWalker2_validate	-0.199913300179198	0.0127451868856718		NA	NA	NA
hsa-miR-16-5p	CHD3	0.749619098384047	4.11649450706988e-06	-0.241570460995394	0.100045346328507	miRNAWalker2_validate	-0.102298538285912	0.0136730818512187		NA	NA	NA
hsa-miR-16-5p	CHD9	0.749619098384047	4.11649450706988e-06	-0.374845697772781	0.00501909690303923	miRNATAP	-0.128826790227191	0.000633260733325645		NA	NA	NA
hsa-miR-193b-3p	CHDH	1.10444771306846	0.000822888533401377	0.038964820721259	0.880605608718859	miRNAWalker2_validate	-0.160709194070634	6.75799012110717e-06		NA	NA	NA
hsa-miR-16-5p	CLIP2	0.749619098384047	4.11649450706988e-06	-0.664448360966921	0.00205157128268499	miRNAWalker2_validate	-0.198406983839293	0.00115599078981735		NA	NA	NA
hsa-miR-16-5p	CNN1	0.749619098384047	4.11649450706988e-06	-1.85601870601215	4.21709534458184e-09	miRNATAP	-0.557079070030276	4.61261888989802e-10		NA	NA	NA
hsa-miR-16-5p	CNN3	0.749619098384047	4.11649450706988e-06	-0.90517420289371	1.66752829840865e-07	miRNAWalker2_validate	-0.116465450813253	0.0187768126114931		NA	NA	NA
hsa-miR-16-5p	CNNM2	0.749619098384047	4.11649450706988e-06	-0.165324540953705	0.189620656318586	miRNAWalker2_validate	-0.160185009041722	5.57024286803727e-06		NA	NA	NA
hsa-miR-16-5p	CNTNAP1	0.749619098384047	4.11649450706988e-06	-0.0658420171526113	0.738577030970608	MirTarget	-0.194458135629516	0.000463133734789682		NA	NA	NA
hsa-miR-16-5p	COBLL1	0.749619098384047	4.11649450706988e-06	-0.936329208296367	1.24981603771865e-06	MirTarget;miRNATAP	-0.13354348856041	0.0156341669684136		NA	NA	NA
hsa-miR-16-5p	COL12A1	0.749619098384047	4.11649450706988e-06	-0.849027180514303	0.034965601861609	MirTarget;miRNATAP	-0.602147905536878	9.33094829038679e-08		NA	NA	NA
hsa-miR-16-5p	COL4A1	0.749619098384047	4.11649450706988e-06	-0.171188584989235	0.444957041661407	miRNAWalker2_validate	-0.305665949761596	1.10858365302114e-06		NA	NA	NA
hsa-miR-16-5p	COL4A2	0.749619098384047	4.11649450706988e-06	-0.618750645591112	0.00595258274491188	miRNAWalker2_validate	-0.32451853983148	2.74433880065982e-07		NA	NA	NA
hsa-miR-16-5p	COL4A4	0.749619098384047	4.11649450706988e-06	-1.76080263941118	9.82662874760881e-07	mirMAP	-0.436798298681975	1.97692083914873e-05		NA	NA	NA
hsa-miR-16-5p	CPD	0.749619098384047	4.11649450706988e-06	0.911876479581357	9.08443596366211e-05	MirTarget;miRNATAP	-0.198309913976679	0.00276903278850713		NA	NA	NA
hsa-miR-16-5p	CREB3L2	0.749619098384047	4.11649450706988e-06	0.456460806139882	0.00403307619810407	miRNAWalker2_validate	-0.201442667495513	6.42967626985123e-06		NA	NA	NA
hsa-miR-16-5p	CRIM1	0.749619098384047	4.11649450706988e-06	-1.64124339109809	1.05920757248863e-14	MirTarget;miRNATAP	-0.263711911614038	1.79604416326327e-05		NA	NA	NA
hsa-miR-16-5p	CRTC3	0.749619098384047	4.11649450706988e-06	-0.605496798087843	1.18411742527865e-08	miRNATAP	-0.167985766367786	2.11300030694446e-08		NA	NA	NA
hsa-miR-16-5p	CSGALNACT1	0.749619098384047	4.11649450706988e-06	-0.938093900217929	5.02022091000902e-05	miRNAWalker2_validate	-0.331928684190451	3.64953594506951e-07		NA	NA	NA
hsa-miR-193b-3p	CSRNP1	1.10444771306846	0.000822888533401377	-2.37130713535094	3.68062140953577e-28	MirTarget	-0.153246109327889	1.17158814575923e-06		NA	NA	NA
hsa-miR-16-5p	CTDSPL	0.749619098384047	4.11649450706988e-06	-1.17175267855219	5.42160099430112e-13	miRNATAP	-0.174193206393319	0.000205622755922864		NA	NA	NA
hsa-miR-193b-3p	CTNND2	1.10444771306846	0.000822888533401377	-3.28725012688357	3.16947700174299e-05	MirTarget	-0.242143270667837	0.0287791435939477		NA	NA	NA
hsa-miR-16-5p	CX3CL1	0.749619098384047	4.11649450706988e-06	-1.34281361817391	0.000237116872545159	miRNATAP	-0.346152657485002	0.000850449194049338		NA	NA	NA
hsa-miR-16-5p	CYB561D1	0.749619098384047	4.11649450706988e-06	-0.667833754599991	1.93860188865877e-05	mirMAP	-0.125413742239277	0.00482529362101499		NA	NA	NA
hsa-miR-16-5p	CYS1	0.749619098384047	4.11649450706988e-06	-2.40839755982089	1.75157575977981e-09	mirMAP	-0.617292108936242	6.01468025441521e-08		NA	NA	NA
hsa-miR-16-5p	DAB2IP	0.749619098384047	4.11649450706988e-06	-1.15489685122248	4.21527998530257e-13	mirMAP	-0.12906478189551	0.00520115260176077		NA	NA	NA
hsa-miR-16-5p	DCLK1	0.749619098384047	4.11649450706988e-06	0.49016583658974	0.163759727530242	miRNATAP	-0.211416362577359	0.0339973798253152		NA	NA	NA
hsa-miR-16-5p	DENND2C	0.749619098384047	4.11649450706988e-06	-1.17939216515295	2.82946980127707e-07	MirTarget	-0.156144998134475	0.0177080840345931		NA	NA	NA
hsa-miR-16-5p	DGCR2	0.749619098384047	4.11649450706988e-06	-0.0822314358708116	0.531844353072212	mirMAP	-0.124893745585087	0.000729755775440622		NA	NA	NA
hsa-miR-16-5p	DIXDC1	0.749619098384047	4.11649450706988e-06	-1.41147252485962	4.11474328372489e-17	miRNAWalker2_validate;MirTarget	-0.236809484522442	1.17088898862854e-06		NA	NA	NA
hsa-miR-16-5p	DLL1	0.749619098384047	4.11649450706988e-06	-1.10182190980285	0.000199876846514913	miRNATAP	-0.171717878655405	0.0420391876193722		NA	NA	NA
hsa-miR-16-5p	DLL4	0.749619098384047	4.11649450706988e-06	-0.95277772563572	2.13522684396144e-06	miRNATAP	-0.239965944744621	2.64160944058487e-05		NA	NA	NA
hsa-miR-16-5p	DMD	0.749619098384047	4.11649450706988e-06	-1.31312850973335	3.19005914779323e-06	miRNAWalker2_validate	-0.224384091790979	0.00533639859990774		NA	NA	NA
hsa-miR-16-5p	DOCK5	0.749619098384047	4.11649450706988e-06	0.0488838514060843	0.858986988312894	miRNAWalker2_validate	-0.228011088265712	0.0033293583617779		NA	NA	NA
hsa-miR-16-5p	DOCK9	0.749619098384047	4.11649450706988e-06	-1.09326238857057	1.00749207898571e-08	miRNAWalker2_validate	-0.252999892334814	3.28349544461274e-06		NA	NA	NA
hsa-miR-193b-3p	DOK2	1.10444771306846	0.000822888533401377	-2.10493664253159	3.17692968298124e-15	miRNAWalker2_validate	-0.185643176995613	9.67249308852254e-07		NA	NA	NA
hsa-miR-16-5p	DSEL	0.749619098384047	4.11649450706988e-06	-0.887564595581258	0.00132066687284569	MirTarget;miRNATAP	-0.221331264090858	0.00479662790851632		NA	NA	NA
hsa-miR-16-5p	DYNC1I1	0.749619098384047	4.11649450706988e-06	-0.10503838689404	0.776854288584205	MirTarget;miRNATAP	-0.266403389091401	0.0110095050435012		NA	NA	NA
hsa-miR-16-5p	DZIP1	0.749619098384047	4.11649450706988e-06	-0.738204944601599	0.00146765359739136	MirTarget	-0.21955280875761	0.000840405835204967		NA	NA	NA
hsa-miR-16-5p	EDA	0.749619098384047	4.11649450706988e-06	-1.39703227003483	0.000120616105379714	MirTarget;miRNATAP	-0.258750527452374	0.0124609847119922		NA	NA	NA
hsa-miR-16-5p	EFNB2	0.749619098384047	4.11649450706988e-06	-1.34251874593326	5.65346504979253e-08	miRNAWalker2_validate;miRNATAP	-0.149906130906208	0.0348594267120502		NA	NA	NA
hsa-miR-193b-3p	EFS	1.10444771306846	0.000822888533401377	-0.228038395723936	0.502557160871858	miRNAWalker2_validate	-0.124303672859089	0.00841447083807229		NA	NA	NA
hsa-miR-16-5p	EGFR	0.749619098384047	4.11649450706988e-06	-0.271157231776117	0.423394925561077	miRNAWalker2_validate	-0.236322665103673	0.0136370655603559		NA	NA	NA
hsa-miR-16-5p	ELMOD1	0.749619098384047	4.11649450706988e-06	-2.82348645023585	1.70616378681512e-13	MirTarget	-0.222027538109134	0.0466882505476953		NA	NA	NA
hsa-miR-16-5p	EML4	0.749619098384047	4.11649450706988e-06	0.356177347900029	0.0111822776541039	miRNAWalker2_validate	-0.117606589908289	0.0030273153021772		NA	NA	NA
hsa-miR-16-5p	ENAH	0.749619098384047	4.11649450706988e-06	0.516209965224187	0.00055432042456977	MirTarget;miRNATAP	-0.100034890643327	0.018448225533204		NA	NA	NA
hsa-miR-193b-3p	ENAM	1.10444771306846	0.000822888533401377	-1.28122043928837	0.0362708415113674	MirTarget	-0.425427029923254	4.42028646080288e-07		NA	NA	NA
hsa-miR-193b-3p	ENDOD1	1.10444771306846	0.000822888533401377	0.0574724229589449	0.802287884473109	miRNAWalker2_validate	-0.193643641182539	6.00652244423002e-10		NA	NA	NA
hsa-miR-16-5p	ENTPD7	0.749619098384047	4.11649450706988e-06	0.961993660603616	1.96769185666073e-08	MirTarget	-0.135088339373434	0.00597995165449741		NA	NA	NA
hsa-miR-16-5p	EPB41L1	0.749619098384047	4.11649450706988e-06	-0.289748977160756	0.0609014792511306	MirTarget	-0.135789847625799	0.00184939964988839		NA	NA	NA
hsa-miR-193b-3p	EPDR1	1.10444771306846	0.000822888533401377	-0.824836525429171	0.00765843230141196	miRNAWalker2_validate	-0.151163821082796	0.000428686330916193		NA	NA	NA
hsa-miR-16-5p	EPHA1	0.749619098384047	4.11649450706988e-06	0.651383261071748	0.0208328466597216	miRNATAP	-0.171534189033795	0.0319496189031329		NA	NA	NA
hsa-miR-193b-3p	ERBB4	1.10444771306846	0.000822888533401377	-3.25765319323352	4.89348718759411e-11	MirTarget;miRNATAP	-0.457545689579631	3.23361246461714e-11		NA	NA	NA
hsa-miR-193b-3p	ESR1	1.10444771306846	0.000822888533401377	-0.25644373220173	0.510273598637747	miRNAWalker2_validate;miRTarBase	-0.174457691281179	0.00121635396366208		NA	NA	NA
hsa-miR-16-5p	ESRRG	0.749619098384047	4.11649450706988e-06	-0.628600894826721	0.208645421398893	miRNATAP	-0.291376600013075	0.0397124672969775		NA	NA	NA
hsa-miR-193b-3p	ETV1	1.10444771306846	0.000822888533401377	-1.78691067165157	1.57701017400102e-09	MirTarget;miRNATAP	-0.329665414929338	4.33175988326256e-16		NA	NA	NA
hsa-miR-16-5p	EXOC3L2	0.749619098384047	4.11649450706988e-06	-0.546797544626844	0.0135074691351134	miRNATAP	-0.144346861025038	0.0214789895420445		NA	NA	NA
hsa-miR-16-5p	EYA4	0.749619098384047	4.11649450706988e-06	-2.92568608978114	3.39770912672617e-09	MirTarget	-0.423784314784065	0.00291978960550176		NA	NA	NA
hsa-miR-16-5p	FAM168A	0.749619098384047	4.11649450706988e-06	-0.323399937996444	0.0970753484286064	miRNAWalker2_validate	-0.218649314198795	6.69186667633922e-05		NA	NA	NA
hsa-miR-16-5p	FAM189A1	0.749619098384047	4.11649450706988e-06	-3.26331839326516	5.65998390105529e-14	MirTarget;miRNATAP	-0.416737820438355	0.00095874997968109		NA	NA	NA
hsa-miR-16-5p	FAM69A	0.749619098384047	4.11649450706988e-06	0.748871923288184	7.63249901095162e-06	miRNAWalker2_validate	-0.167146695973063	0.000442938586110515		NA	NA	NA
hsa-miR-16-5p	FAM81A	0.749619098384047	4.11649450706988e-06	1.29784392429988	1.81188452493522e-05	miRNATAP	-0.18440779642182	0.0330225849234164		NA	NA	NA
hsa-miR-16-5p	FAM84B	0.749619098384047	4.11649450706988e-06	0.468049180591273	0.0261496317194756	MirTarget	-0.153718479751192	0.00989299334764048		NA	NA	NA
hsa-miR-16-5p	FAM89A	0.749619098384047	4.11649450706988e-06	-0.966096988851727	6.22393584563865e-05	miRNAWalker2_validate;MirTarget	-0.157659294980203	0.0219279054863344		NA	NA	NA
hsa-miR-16-5p	FAT3	0.749619098384047	4.11649450706988e-06	-3.31351022608528	4.74987714919919e-14	miRNAWalker2_validate;MirTarget;miRNATAP	-0.417455646239267	0.00108754080961958		NA	NA	NA
hsa-miR-16-5p	FAT4	0.749619098384047	4.11649450706988e-06	-1.93555989508872	5.84085474109382e-11	MirTarget	-0.342103589469737	5.73784731417634e-05		NA	NA	NA
hsa-miR-193b-3p	FAT4	1.10444771306846	0.000822888533401377	-1.93555989508872	5.84085474109382e-11	MirTarget;miRNATAP	-0.289574776078426	1.592286588535e-12		NA	NA	NA
hsa-miR-16-5p	FBXO21	0.749619098384047	4.11649450706988e-06	-0.437334802422712	0.000165351761753665	MirTarget;miRNATAP	-0.130432421865829	6.86267243342783e-05		NA	NA	NA
hsa-miR-193b-3p	FCHSD2	1.10444771306846	0.000822888533401377	-0.522191006907339	4.96376151948058e-06	MirTarget	-0.100758695169391	1.29165572687432e-10		NA	NA	NA
hsa-miR-16-5p	FERMT2	0.749619098384047	4.11649450706988e-06	-1.54180889001218	9.12884009580181e-21	MirTarget;miRNATAP	-0.117482110600466	0.0159855086966405		NA	NA	NA
hsa-miR-16-5p	FGF18	0.749619098384047	4.11649450706988e-06	-2.01878202132787	1.47991026443687e-06	miRNATAP	-0.278033638119358	0.0206297444111895		NA	NA	NA
hsa-miR-16-5p	FGF7	0.749619098384047	4.11649450706988e-06	-1.35096332880614	7.44222727225117e-07	miRNATAP	-0.360407939054601	3.33302283380507e-06		NA	NA	NA
hsa-miR-16-5p	FGF9	0.749619098384047	4.11649450706988e-06	-1.33489997634345	0.0119359510527769	miRNATAP	-0.466038608257105	0.00194558955642264		NA	NA	NA
hsa-miR-16-5p	FGFR1	0.749619098384047	4.11649450706988e-06	-0.915442355826397	0.000285266909471616	miRTarBase;miRNATAP	-0.246942745271025	0.000561455743835118	21532615	Such downregulation of miR-15 and miR-16 in cancer-associated fibroblasts CAFs promoted tumor growth and progression through the reduced post-transcriptional repression of Fgf-2 and its receptor Fgfr1 which act on both stromal and tumor cells to enhance cancer cell survival proliferation and migration	progression;poor survival	prostate cancer
hsa-miR-193b-3p	FHDC1	1.10444771306846	0.000822888533401377	-1.22622484311371	1.1061627607329e-08	MirTarget;miRNATAP	-0.103396541584612	0.000611953415088722		NA	NA	NA
hsa-miR-193b-3p	FLI1	1.10444771306846	0.000822888533401377	-1.88163703190108	4.58488254748209e-20	MirTarget	-0.1738354809807	2.82695183433817e-09		NA	NA	NA
hsa-miR-16-5p	FLNA	0.749619098384047	4.11649450706988e-06	-0.924583916672365	4.56435160750428e-05	miRNAWalker2_validate	-0.290737189049525	5.84415867008081e-06		NA	NA	NA
hsa-miR-193b-3p	FLRT3	1.10444771306846	0.000822888533401377	-2.4278272258789	3.94867354801025e-10	MirTarget;miRNATAP	-0.288851168099617	1.05654382155842e-07		NA	NA	NA
hsa-miR-16-5p	FNDC3B	0.749619098384047	4.11649450706988e-06	0.223414257121579	0.124320565574543	miRNAWalker2_validate;MirTarget	-0.102632074727479	0.0124042026252017		NA	NA	NA
hsa-miR-193b-3p	FOXC1	1.10444771306846	0.000822888533401377	-0.230594791432115	0.464301237065496	miRNAWalker2_validate	-0.127999201092606	0.00337523829343173		NA	NA	NA
hsa-miR-16-5p	FRMPD1	0.749619098384047	4.11649450706988e-06	-2.73811410062828	1.20282884463218e-09	MirTarget	-0.319921727355201	0.0137805111618562		NA	NA	NA
hsa-miR-16-5p	FRY	0.749619098384047	4.11649450706988e-06	-1.86522482005448	1.07395091737952e-15	miRNATAP	-0.315742186961678	2.83671621048024e-06		NA	NA	NA
hsa-miR-16-5p	FSCN2	0.749619098384047	4.11649450706988e-06	0.522602732377855	0.108134436425981	miRNAWalker2_validate	-0.281114208210932	0.00223009274776377		NA	NA	NA
hsa-miR-16-5p	FZD4	0.749619098384047	4.11649450706988e-06	-1.78542446608909	5.91969949280441e-18	MirTarget	-0.144766448178282	0.0172105177944577		NA	NA	NA
hsa-miR-16-5p	GHR	0.749619098384047	4.11649450706988e-06	-2.71079913438272	1.27737998879726e-18	MirTarget;miRNATAP	-0.370703042948598	3.89836833751239e-05		NA	NA	NA
hsa-miR-193b-3p	GIMAP2	1.10444771306846	0.000822888533401377	-0.99345489360746	2.72960027175985e-05	miRNAWalker2_validate	-0.187997760110062	8.69959075730604e-09		NA	NA	NA
hsa-miR-16-5p	GNAL	0.749619098384047	4.11649450706988e-06	-0.585195976222207	0.0597590517902974	miRNAWalker2_validate;miRNATAP	-0.236816306714919	0.00711936163889266		NA	NA	NA
hsa-miR-16-5p	GNAO1	0.749619098384047	4.11649450706988e-06	0.00310939701191604	0.992262909193059	mirMAP	-0.26342888377256	0.00362107308783807		NA	NA	NA
hsa-miR-193b-3p	GNAO1	1.10444771306846	0.000822888533401377	0.00310939701191604	0.992262909193059	MirTarget	-0.10034086232519	0.0241586591136719		NA	NA	NA
hsa-miR-16-5p	GPATCH8	0.749619098384047	4.11649450706988e-06	0.0643141219086125	0.518738011249824	MirTarget	-0.101424780878135	0.000278766522576418		NA	NA	NA
hsa-miR-16-5p	GPR153	0.749619098384047	4.11649450706988e-06	-0.586248172281513	0.0223775005764331	miRNATAP	-0.223765221534719	0.00206025081028897		NA	NA	NA
hsa-miR-16-5p	GPR157	0.749619098384047	4.11649450706988e-06	-0.0433587648814191	0.8518009548488	miRNAWalker2_validate	-0.221162074460994	0.000719658711932669		NA	NA	NA
hsa-miR-16-5p	GPRIN2	0.749619098384047	4.11649450706988e-06	-2.52060469837327	1.68732774615191e-10	mirMAP	-0.283225872163688	0.0130007662243913		NA	NA	NA
hsa-miR-16-5p	GRAMD3	0.749619098384047	4.11649450706988e-06	0.731946012534302	9.39240273680761e-06	MirTarget	-0.153404343221884	0.00109880295278898		NA	NA	NA
hsa-miR-193b-3p	GRIK3	1.10444771306846	0.000822888533401377	-0.465658538871947	0.380358482544615	mirMAP	-0.158083369276797	0.0320873664305349		NA	NA	NA
hsa-miR-16-5p	HHIPL1	0.749619098384047	4.11649450706988e-06	0.0306471100576042	0.914508462245204	mirMAP	-0.237865718133941	0.00316106664657918		NA	NA	NA
hsa-miR-16-5p	HIPK2	0.749619098384047	4.11649450706988e-06	-0.416279719153451	0.045621163498721	miRNATAP	-0.121148129066145	0.0400842039670084		NA	NA	NA
hsa-miR-16-5p	HPSE2	0.749619098384047	4.11649450706988e-06	-4.08508167119523	1.4818249289855e-18	MirTarget	-0.673175463999526	6.80606801033273e-07		NA	NA	NA
hsa-miR-16-5p	HS6ST1	0.749619098384047	4.11649450706988e-06	0.0446015172756846	0.801401031688771	mirMAP	-0.129473150918334	0.0096784532603109		NA	NA	NA
hsa-miR-16-5p	HSPG2	0.749619098384047	4.11649450706988e-06	-0.504680410615252	0.0208897135044859	MirTarget	-0.365431073689012	1.99708015204287e-09		NA	NA	NA
hsa-miR-16-5p	HTRA1	0.749619098384047	4.11649450706988e-06	-0.310202864896358	0.156178595808374	miRNAWalker2_validate	-0.293413401185039	1.70870336733449e-06		NA	NA	NA
hsa-miR-16-5p	HTT	0.749619098384047	4.11649450706988e-06	-0.389418684706523	0.00268311882552241	miRNAWalker2_validate;MirTarget	-0.11523281122444	0.00167002890290922		NA	NA	NA
hsa-miR-16-5p	ICOSLG	0.749619098384047	4.11649450706988e-06	-0.194260555087396	0.259219722553666	mirMAP	-0.105598036532338	0.0300399042275676		NA	NA	NA
hsa-miR-16-5p	IDS	0.749619098384047	4.11649450706988e-06	-0.27128760260832	0.135611573919241	miRNAWalker2_validate	-0.188342543903096	0.000233508106517144		NA	NA	NA
hsa-miR-16-5p	IGF1R	0.749619098384047	4.11649450706988e-06	-0.178629243747184	0.436534266278541	miRNATAP	-0.128074947776339	0.0486849278613552	23507142	Furthermore we confirmed that IGF1R is a direct target of miR-16; In clinical specimens IGF1R levels inversely correlate with miR-16 expression; Our results provide significant clues regarding the role of miR-16 as a tumor suppressor by targeting IGF1R in OS		sarcoma
hsa-miR-16-5p	IGF2R	0.749619098384047	4.11649450706988e-06	-0.4586244526527	0.00374352263056944	miRNAWalker2_validate;MirTarget	-0.139850520060519	0.00177790111167608		NA	NA	NA
hsa-miR-16-5p	IGSF9B	0.749619098384047	4.11649450706988e-06	1.08515249469163	0.031033802609287	mirMAP	-0.428928349247623	0.00260208882783903		NA	NA	NA
hsa-miR-193b-3p	IGSF9B	1.10444771306846	0.000822888533401377	1.08515249469163	0.031033802609287	mirMAP	-0.243295985182096	0.000488613499497027		NA	NA	NA
hsa-miR-16-5p	IL17RA	0.749619098384047	4.11649450706988e-06	-0.708307467253015	1.07411424263016e-07	mirMAP	-0.13302992827354	0.000466614802700782		NA	NA	NA
hsa-miR-193b-3p	IL6R	1.10444771306846	0.000822888533401377	-1.1746226729414	2.27195491770167e-06	mirMAP	-0.183254512449137	1.0448823932318e-07		NA	NA	NA
hsa-miR-16-5p	IMPAD1	0.749619098384047	4.11649450706988e-06	0.0917866744195983	0.481682586474374	miRNAWalker2_validate	-0.107047491253131	0.00355898798424401		NA	NA	NA
hsa-miR-16-5p	INSR	0.749619098384047	4.11649450706988e-06	0.072568705841749	0.687422001875906	miRNATAP	-0.254218737256182	4.56844501195278e-07		NA	NA	NA
hsa-miR-16-5p	ISLR	0.749619098384047	4.11649450706988e-06	0.161418609051105	0.562331438964405	MirTarget;miRNATAP	-0.41873265015567	7.40180550596596e-08		NA	NA	NA
hsa-miR-16-5p	ITGA10	0.749619098384047	4.11649450706988e-06	-1.74852949466288	4.70137862221896e-07	MirTarget	-0.234232536958384	0.0185643382089116		NA	NA	NA
hsa-miR-16-5p	ITGA2	0.749619098384047	4.11649450706988e-06	0.819741688063703	0.0236624943026744	miRNAWalker2_validate;MirTarget;miRNATAP	-0.332696009737313	0.00116943184349703		NA	NA	NA
hsa-miR-16-5p	ITGB4	0.749619098384047	4.11649450706988e-06	0.895169889709774	0.0139079049309048	miRNAWalker2_validate	-0.283852854927185	0.00593336832805821		NA	NA	NA
hsa-miR-16-5p	KALRN	0.749619098384047	4.11649450706988e-06	-0.724336200459316	0.00388205285927654	miRNATAP	-0.188814151565468	0.00798071111047918		NA	NA	NA
hsa-miR-193b-3p	KBTBD11	1.10444771306846	0.000822888533401377	-0.824058453992785	0.00476021079463218	miRNAWalker2_validate	-0.145082506857046	0.000342631826036402		NA	NA	NA
hsa-miR-16-5p	KCNA6	0.749619098384047	4.11649450706988e-06	-1.55187960972656	1.94012978391101e-05	MirTarget	-0.245614818983438	0.0179260091577159		NA	NA	NA
hsa-miR-16-5p	KCNAB1	0.749619098384047	4.11649450706988e-06	-2.04281759220172	1.56047575904229e-23	MirTarget;miRNATAP	-0.172570474346932	0.00451138825204998		NA	NA	NA
hsa-miR-16-5p	KCNC4	0.749619098384047	4.11649450706988e-06	-0.639432659371663	0.000502738971424206	miRNAWalker2_validate	-0.20581141064101	7.47057393985153e-05		NA	NA	NA
hsa-miR-16-5p	KCND3	0.749619098384047	4.11649450706988e-06	-1.39479087676062	0.00156094061640057	miRNAWalker2_validate	-0.41711066716028	0.000850537509722853		NA	NA	NA
hsa-miR-16-5p	KCNIP1	0.749619098384047	4.11649450706988e-06	-2.66431511859907	1.16448763454108e-13	MirTarget	-0.215296991588048	0.0396145181333509		NA	NA	NA
hsa-miR-16-5p	KCNJ2	0.749619098384047	4.11649450706988e-06	-1.33214868628928	7.3119423516575e-07	MirTarget;miRNATAP	-0.176411935308462	0.0220597019235238		NA	NA	NA
hsa-miR-193b-3p	KCNJ2	1.10444771306846	0.000822888533401377	-1.33214868628928	7.3119423516575e-07	miRNATAP	-0.162913491489438	1.42255043661614e-05		NA	NA	NA
hsa-miR-193b-3p	KCNQ5	1.10444771306846	0.000822888533401377	1.52459159958493	0.00120098531045769	MirTarget;miRNATAP	-0.309999591332325	1.92729568860809e-06		NA	NA	NA
hsa-miR-16-5p	KCTD1	0.749619098384047	4.11649450706988e-06	0.45742180960516	0.0332490294299191	miRNATAP	-0.119769834935193	0.0492804006882436		NA	NA	NA
hsa-miR-16-5p	KDR	0.749619098384047	4.11649450706988e-06	-1.29217133319599	5.17137540720335e-06	miRTarBase;miRNATAP	-0.302391399126077	0.000178613946334273	26934556	The expression levels of two target genes Myb and VEGFR2 were affected significantly by miR-16 while glucose administration inhibited miR-16 expression and enhanced tumor cell proliferation and migration; Hyperglycemia can impact the clinical outcomes of CRC patients likely by inhibiting miR-16 expression and the expression of its downstream genes Myb and VEGFR2		colorectal cancer
hsa-miR-16-5p	KIAA1614	0.749619098384047	4.11649450706988e-06	-1.15140364762368	1.39907043789929e-06	mirMAP	-0.273650643803955	5.57919100596602e-05		NA	NA	NA
hsa-miR-16-5p	KIDINS220	0.749619098384047	4.11649450706988e-06	-0.435296925303464	0.000199615324009201	miRNAWalker2_validate	-0.141589852538555	1.75763088938509e-05		NA	NA	NA
hsa-miR-16-5p	KIF13B	0.749619098384047	4.11649450706988e-06	-0.421992956991057	0.0584039774168022	mirMAP	-0.263922866954859	2.58183467706459e-05		NA	NA	NA
hsa-miR-16-5p	KIF16B	0.749619098384047	4.11649450706988e-06	-0.208714455849737	0.165742038134746	miRNATAP	-0.143024324334962	0.000743368121714564		NA	NA	NA
hsa-miR-16-5p	KIF1C	0.749619098384047	4.11649450706988e-06	-1.40025406363242	2.04407418110822e-21	miRNATAP	-0.144451550347043	0.000891597090011046		NA	NA	NA
hsa-miR-16-5p	KIF3B	0.749619098384047	4.11649450706988e-06	-0.204154066663011	0.0996701874799913	MirTarget	-0.111292098747499	0.00142970137048257		NA	NA	NA
hsa-miR-16-5p	KIRREL	0.749619098384047	4.11649450706988e-06	-0.932331146450478	0.00176701682090641	mirMAP	-0.42873119993475	3.15320439013139e-07		NA	NA	NA
hsa-miR-16-5p	KLF13	0.749619098384047	4.11649450706988e-06	-1.61416344728741	1.73032705805029e-20	mirMAP	-0.187055374069328	0.000258488621118429		NA	NA	NA
hsa-miR-16-5p	LAMB1	0.749619098384047	4.11649450706988e-06	-0.575813191835882	0.00496768662503512	miRNAWalker2_validate	-0.244623247996028	2.2979042389839e-05		NA	NA	NA
hsa-miR-16-5p	LAMB3	0.749619098384047	4.11649450706988e-06	0.471498489772865	0.162074139690299	miRNAWalker2_validate	-0.248716947851821	0.00914395779954672		NA	NA	NA
hsa-miR-16-5p	LAMC1	0.749619098384047	4.11649450706988e-06	-0.110787086889143	0.490508859847474	miRNAWalker2_validate;MirTarget	-0.116726223728925	0.0100388170101333		NA	NA	NA
hsa-miR-16-5p	LATS1	0.749619098384047	4.11649450706988e-06	-0.447822414619614	0.00448864298940338	miRNAWalker2_validate;MirTarget;miRNATAP	-0.141327561968826	0.00151761807447412		NA	NA	NA
hsa-miR-16-5p	LATS2	0.749619098384047	4.11649450706988e-06	-1.31460097903989	2.33618473997196e-19	miRNATAP	-0.171273988603932	6.25788427868163e-05		NA	NA	NA
hsa-miR-16-5p	LCOR	0.749619098384047	4.11649450706988e-06	0.637403193132661	0.0037407933451203	miRNATAP	-0.187000740986207	0.00268396501508258		NA	NA	NA
hsa-miR-193b-3p	LCOR	1.10444771306846	0.000822888533401377	0.637403193132661	0.0037407933451203	miRNAWalker2_validate	-0.11512625005715	0.00015863408274504		NA	NA	NA
hsa-miR-16-5p	LDOC1L	0.749619098384047	4.11649450706988e-06	-0.304589446384855	0.0361507713624303	mirMAP	-0.186955296652737	4.52479096961377e-06		NA	NA	NA
hsa-miR-16-5p	LIMA1	0.749619098384047	4.11649450706988e-06	-0.211096882428467	0.156864115360198	miRNAWalker2_validate	-0.137434631368195	0.00106729805548605		NA	NA	NA
hsa-miR-16-5p	LMO7	0.749619098384047	4.11649450706988e-06	-1.51547893375172	1.14584058132002e-12	miRNAWalker2_validate	-0.133765302594459	0.0306488704509254		NA	NA	NA
hsa-miR-16-5p	LMTK3	0.749619098384047	4.11649450706988e-06	0.261953589510207	0.332699701536252	miRNAWalker2_validate	-0.205245298996212	0.00724371774271596		NA	NA	NA
hsa-miR-16-5p	LONRF2	0.749619098384047	4.11649450706988e-06	-0.33903877936793	0.454806268413865	miRNAWalker2_validate;mirMAP	-0.337348647945817	0.00854054780455003		NA	NA	NA
hsa-miR-193b-3p	LPCAT1	1.10444771306846	0.000822888533401377	-0.519174790397356	0.0805461797273132	miRNAWalker2_validate;MirTarget	-0.228559763565698	1.99058942230728e-08		NA	NA	NA
hsa-miR-16-5p	LRP6	0.749619098384047	4.11649450706988e-06	-0.330500567304233	0.0478105745633487	miRNATAP	-0.128840552259652	0.00633835808300635		NA	NA	NA
hsa-miR-16-5p	LRRK1	0.749619098384047	4.11649450706988e-06	-0.476367862938304	0.0273009774306059	MirTarget	-0.138809474312354	0.0232381792193143		NA	NA	NA
hsa-miR-16-5p	LUZP1	0.749619098384047	4.11649450706988e-06	-0.655744372669356	5.83438248114919e-06	miRNAWalker2_validate;MirTarget;miRNATAP	-0.164748248281521	5.94444242405566e-05		NA	NA	NA
hsa-miR-16-5p	MACF1	0.749619098384047	4.11649450706988e-06	-1.01679650501995	2.90355716680359e-10	miRNAWalker2_validate	-0.201390072309331	1.28935214880209e-05		NA	NA	NA
hsa-miR-16-5p	MAN2B2	0.749619098384047	4.11649450706988e-06	-0.409953640434336	0.00167828973179241	mirMAP	-0.10456405582691	0.00463091480547312		NA	NA	NA
hsa-miR-16-5p	MAP3K3	0.749619098384047	4.11649450706988e-06	-1.14767015293789	1.13947111671358e-17	MirTarget;miRNATAP	-0.103380222383782	0.00848322326050329		NA	NA	NA
hsa-miR-193b-3p	MAP3K3	1.10444771306846	0.000822888533401377	-1.14767015293789	1.13947111671358e-17	miRNAWalker2_validate;miRNATAP	-0.116959872215266	6.79135085437139e-10		NA	NA	NA
hsa-miR-16-5p	MAP4	0.749619098384047	4.11649450706988e-06	-0.762529258951489	4.80838224687904e-12	miRNAWalker2_validate	-0.133987759498613	2.29673380772723e-05		NA	NA	NA
hsa-miR-16-5p	MAP7	0.749619098384047	4.11649450706988e-06	0.444391918230147	0.0106684371761414	miRNAWalker2_validate;MirTarget;miRNATAP	-0.171743414035946	0.000474280697584362		NA	NA	NA
hsa-miR-193b-3p	MBNL3	1.10444771306846	0.000822888533401377	-0.874006580481467	0.00178579729687017	miRNATAP	-0.19554652176728	4.07340559175583e-07		NA	NA	NA
hsa-miR-193b-3p	MBP	1.10444771306846	0.000822888533401377	-0.922052075942358	4.12083786820759e-08	mirMAP	-0.101634922508555	1.5194225985888e-05		NA	NA	NA
hsa-miR-16-5p	MED12	0.749619098384047	4.11649450706988e-06	-0.0194332642814938	0.878297047493076	miRNAWalker2_validate	-0.130613749756219	0.000245150651026761		NA	NA	NA
hsa-miR-16-5p	MED13	0.749619098384047	4.11649450706988e-06	0.164671789363017	0.212452325463008	miRNAWalker2_validate;miRNATAP	-0.135374165979844	0.000264359209700553		NA	NA	NA
hsa-miR-16-5p	MEGF8	0.749619098384047	4.11649450706988e-06	-0.153582079231931	0.347220173142739	miRNAWalker2_validate	-0.114343097268474	0.0131853074994165		NA	NA	NA
hsa-miR-16-5p	MEOX2	0.749619098384047	4.11649450706988e-06	-1.67258465568981	3.60495715467905e-07	MirTarget	-0.352281090420237	0.000173411960241777		NA	NA	NA
hsa-miR-16-5p	MFAP5	0.749619098384047	4.11649450706988e-06	-1.11290331271114	0.0382110007219332	MirTarget	-0.592128917042917	9.27376495763723e-05		NA	NA	NA
hsa-miR-16-5p	MGAT4A	0.749619098384047	4.11649450706988e-06	-0.482465143207374	0.00555570284492783	miRNAWalker2_validate;MirTarget;miRNATAP	-0.135822859780193	0.00584844196955735		NA	NA	NA
hsa-miR-16-5p	MGAT5	0.749619098384047	4.11649450706988e-06	-0.247727111180191	0.353990823426736	mirMAP	-0.269673831153129	0.000342373029911361		NA	NA	NA
hsa-miR-16-5p	MIB1	0.749619098384047	4.11649450706988e-06	0.110568304748997	0.425281051805314	miRNAWalker2_validate;miRNATAP	-0.100927457401537	0.00984428515608291		NA	NA	NA
hsa-miR-16-5p	MINK1	0.749619098384047	4.11649450706988e-06	-0.626815739217967	6.74111910434242e-08	miRNATAP	-0.138345438511781	2.7641092435081e-05		NA	NA	NA
hsa-miR-16-5p	MKL2	0.749619098384047	4.11649450706988e-06	-0.305148649554948	0.028300365902007	mirMAP	-0.196207493640173	4.64957525686672e-07		NA	NA	NA
hsa-miR-16-5p	MLXIP	0.749619098384047	4.11649450706988e-06	-0.10929714419829	0.470815719239943	mirMAP	-0.205543481784452	1.22760783268499e-06		NA	NA	NA
hsa-miR-16-5p	MMD	0.749619098384047	4.11649450706988e-06	0.217990176204308	0.327678206307607	miRNATAP	-0.128221294067073	0.0418969765598361		NA	NA	NA
hsa-miR-16-5p	MRC2	0.749619098384047	4.11649450706988e-06	-0.980362744305837	1.30992776432251e-05	miRNAWalker2_validate	-0.337996476066979	9.95276412033329e-08		NA	NA	NA
hsa-miR-16-5p	MTM1	0.749619098384047	4.11649450706988e-06	-0.814616455910774	7.01130555946339e-10	miRNATAP	-0.142534632785562	0.000165030641378082		NA	NA	NA
hsa-miR-16-5p	MTMR11	0.749619098384047	4.11649450706988e-06	1.02588215864255	6.61385332621921e-05	MirTarget	-0.219107837509771	0.0027523355056844		NA	NA	NA
hsa-miR-16-5p	MTMR3	0.749619098384047	4.11649450706988e-06	-0.205089931173653	0.139507346583048	MirTarget	-0.143764558091591	0.000229400918026518		NA	NA	NA
hsa-miR-16-5p	MTSS1	0.749619098384047	4.11649450706988e-06	-0.430390277875072	0.102131521255296	miRNATAP	-0.231843955023658	0.0018274611282427		NA	NA	NA
hsa-miR-16-5p	MTSS1L	0.749619098384047	4.11649450706988e-06	-0.0425967082635452	0.823070870790253	mirMAP	-0.202041015950867	0.000162100678982912		NA	NA	NA
hsa-miR-193b-3p	MYB	1.10444771306846	0.000822888533401377	-0.490317224753365	0.0968283089994286	miRNAWalker2_validate	-0.127451758061739	0.00185135444311072		NA	NA	NA
hsa-miR-16-5p	MYLK	0.749619098384047	4.11649450706988e-06	-1.63193711258573	1.44155005364888e-11	MirTarget;miRNATAP	-0.448780246980521	6.09371614549853e-11		NA	NA	NA
hsa-miR-193b-3p	MYLK	1.10444771306846	0.000822888533401377	-1.63193711258573	1.44155005364888e-11	miRNAWalker2_validate	-0.119166935070949	0.000495707370233346		NA	NA	NA
hsa-miR-16-5p	MYO5A	0.749619098384047	4.11649450706988e-06	-0.523684821141466	0.00324176401244809	miRNAWalker2_validate;MirTarget	-0.150136396528118	0.00288221538455642		NA	NA	NA
hsa-miR-16-5p	MYO5B	0.749619098384047	4.11649450706988e-06	-0.505257796085274	0.0200411137788046	miRNAWalker2_validate	-0.139330658242232	0.0236828615430725		NA	NA	NA
hsa-miR-16-5p	NAV1	0.749619098384047	4.11649450706988e-06	0.643081042817989	0.00272015580998536	MirTarget;miRNATAP	-0.146197535514286	0.0163796201889476		NA	NA	NA
hsa-miR-16-5p	NAV2	0.749619098384047	4.11649450706988e-06	0.0250378449602637	0.908451749408439	miRNAWalker2_validate	-0.169162088492507	0.00592128824141217		NA	NA	NA
hsa-miR-193b-3p	NCOA2	1.10444771306846	0.000822888533401377	-0.0982987420367563	0.666359195932011	miRNAWalker2_validate	-0.173479624930892	2.68072416884653e-08		NA	NA	NA
hsa-miR-16-5p	NCOR2	0.749619098384047	4.11649450706988e-06	-0.223020119453697	0.131071558033015	miRNAWalker2_validate;miRTarBase	-0.145930717969193	0.00044776146865129		NA	NA	NA
hsa-miR-16-5p	NDST1	0.749619098384047	4.11649450706988e-06	-1.68425921998113	1.58986813515246e-27	mirMAP	-0.187044816694345	5.26051783329868e-05		NA	NA	NA
hsa-miR-16-5p	NEBL	0.749619098384047	4.11649450706988e-06	-1.91598949856832	2.18839756979729e-11	miRNATAP	-0.220376648674267	0.00779742137069371		NA	NA	NA
hsa-miR-193b-3p	NEDD9	1.10444771306846	0.000822888533401377	-1.99813810235737	2.17652490939562e-14	MirTarget	-0.199025048602813	7.20937253964706e-08		NA	NA	NA
hsa-miR-193b-3p	NFAM1	1.10444771306846	0.000822888533401377	-1.45992906516577	4.7188733950649e-08	mirMAP	-0.115721934354907	0.0020832083582698		NA	NA	NA
hsa-miR-16-5p	NFASC	0.749619098384047	4.11649450706988e-06	-2.01223219081323	6.05102986087567e-10	MirTarget;mirMAP	-0.305310767583984	0.00110466281340875	21081469	NF κB targets miR 16 and miR 21 in gastric cancer: involvement of prostaglandin E receptors		gastric cancer
hsa-miR-193b-3p	NFIC	1.10444771306846	0.000822888533401377	-0.779406692188113	2.42155659995516e-05	mirMAP	-0.1007310392041	8.82980741608643e-05		NA	NA	NA
hsa-miR-16-5p	NIPAL2	0.749619098384047	4.11649450706988e-06	-0.0958244581950876	0.659000702100464	miRNAWalker2_validate	-0.141694509657742	0.0209692408691202		NA	NA	NA
hsa-miR-193b-3p	NLRP3	1.10444771306846	0.000822888533401377	-1.14073646620837	2.76607546756485e-05	miRNAWalker2_validate	-0.19181758483541	3.606665303063e-07		NA	NA	NA
hsa-miR-16-5p	NOS1	0.749619098384047	4.11649450706988e-06	-4.30278289092904	4.98291187091246e-14	miRNATAP	-0.36039807830251	0.0305430934232325		NA	NA	NA
hsa-miR-193b-3p	NOS1	1.10444771306846	0.000822888533401377	-4.30278289092904	4.98291187091246e-14	mirMAP	-0.240987956358128	0.00313488340959473		NA	NA	NA
hsa-miR-16-5p	NOTCH2	0.749619098384047	4.11649450706988e-06	-0.119481238625473	0.492880718191772	miRNAWalker2_validate;MirTarget	-0.181494702892157	0.000212192551661016		NA	NA	NA
hsa-miR-16-5p	NOVA2	0.749619098384047	4.11649450706988e-06	-2.2153233189368	2.91992843639491e-22	mirMAP	-0.188464915281391	0.00538776764534904		NA	NA	NA
hsa-miR-16-5p	NPR3	0.749619098384047	4.11649450706988e-06	-2.217687885014	3.14768338769244e-10	miRNAWalker2_validate	-0.633359447596002	2.35825965073825e-10		NA	NA	NA
hsa-miR-193b-3p	NRIP1	1.10444771306846	0.000822888533401377	0.0607277502606074	0.722985105808803	MirTarget	-0.106862221871578	5.66534128547865e-06		NA	NA	NA
hsa-miR-16-5p	NRP1	0.749619098384047	4.11649450706988e-06	-0.40252187730616	0.0377253868964042	miRNAWalker2_validate	-0.294642674774845	5.30391369687026e-08		NA	NA	NA
hsa-miR-16-5p	NTN1	0.749619098384047	4.11649450706988e-06	-0.771213558369385	0.0344276796510529	mirMAP	-0.271104053231232	0.00868721186984443		NA	NA	NA
hsa-miR-16-5p	NUAK1	0.749619098384047	4.11649450706988e-06	-0.900570031011346	6.21023990828905e-05	MirTarget	-0.415165056458055	3.86647656006968e-11		NA	NA	NA
hsa-miR-16-5p	PAFAH1B2	0.749619098384047	4.11649450706988e-06	-0.288598670796801	0.087837950354388	miRNAWalker2_validate;MirTarget;miRNATAP	-0.153299711509264	0.00130648284476048		NA	NA	NA
hsa-miR-16-5p	PAG1	0.749619098384047	4.11649450706988e-06	-0.653177606505732	0.00714797104690602	miRNAWalker2_validate	-0.145506103711369	0.0348278366842362		NA	NA	NA
hsa-miR-16-5p	PAM	0.749619098384047	4.11649450706988e-06	0.0116352828574593	0.948939132110174	miRNATAP	-0.1277518849542	0.0127579413474414		NA	NA	NA
hsa-miR-16-5p	PAPPA	0.749619098384047	4.11649450706988e-06	-0.441575823679234	0.282684089671432	MirTarget;miRNATAP	-0.328050834293471	0.00475419852679835		NA	NA	NA
hsa-miR-16-5p	PARVA	0.749619098384047	4.11649450706988e-06	-0.74639371511062	2.11812595403209e-08	MirTarget	-0.194956086681562	2.45144728723945e-07		NA	NA	NA
hsa-miR-16-5p	PCDH17	0.749619098384047	4.11649450706988e-06	-1.75615895156376	4.72208249995095e-13	MirTarget;miRNATAP	-0.177063542484903	0.0120606646466407		NA	NA	NA
hsa-miR-16-5p	PCDHA2	0.749619098384047	4.11649450706988e-06	0.24178581588705	0.525928443226555	MirTarget	-0.220411053175853	0.0411530512002315		NA	NA	NA
hsa-miR-16-5p	PCDHA3	0.749619098384047	4.11649450706988e-06	-1.49287562479189	2.09010780196834e-05	MirTarget	-0.253479592695479	0.0113746118255138		NA	NA	NA
hsa-miR-16-5p	PCDHAC2	0.749619098384047	4.11649450706988e-06	-1.84720921471199	1.40037101216076e-05	MirTarget	-0.287379119132414	0.0180288333266305		NA	NA	NA
hsa-miR-16-5p	PCDHGB4	0.749619098384047	4.11649450706988e-06	-0.808245486912361	0.0429967418866854	miRNAWalker2_validate	-0.328199938479935	0.00369450096269025		NA	NA	NA
hsa-miR-16-5p	PDK4	0.749619098384047	4.11649450706988e-06	-3.02809386565859	6.0733772705676e-17	miRNAWalker2_validate;MirTarget;miRNATAP	-0.337937089081986	0.00143110020472967		NA	NA	NA
hsa-miR-16-5p	PDLIM2	0.749619098384047	4.11649450706988e-06	-2.05060176544702	1.46955622154163e-27	mirMAP	-0.192467979456795	0.000653799397084621		NA	NA	NA
hsa-miR-16-5p	PDLIM5	0.749619098384047	4.11649450706988e-06	-0.0692132508054	0.676100118435307	miRNAWalker2_validate;miRNATAP	-0.196449365757502	2.36057088916801e-05		NA	NA	NA
hsa-miR-16-5p	PDPK1	0.749619098384047	4.11649450706988e-06	-0.26368366292376	0.0340750618656775	mirMAP	-0.118430790715905	0.000724062980260007		NA	NA	NA
hsa-miR-16-5p	PDPR	0.749619098384047	4.11649450706988e-06	-0.265459837465167	0.118019717431118	miRNAWalker2_validate;miRNATAP	-0.151388922473453	0.0015742127619393		NA	NA	NA
hsa-miR-193b-3p	PEG10	1.10444771306846	0.000822888533401377	-1.59152448479029	0.00410467550132011	miRNAWalker2_validate	-0.167560751353533	0.0303029754453248		NA	NA	NA
hsa-miR-16-5p	PELI2	0.749619098384047	4.11649450706988e-06	-0.510644742783559	0.0567260405721249	miRNATAP	-0.165476625402763	0.0293539516619391		NA	NA	NA
hsa-miR-193b-3p	PER3	1.10444771306846	0.000822888533401377	-0.595412479621491	0.0348375134144613	MirTarget	-0.179737312109951	3.84738676993776e-06		NA	NA	NA
hsa-miR-16-5p	PFKFB3	0.749619098384047	4.11649450706988e-06	-0.687276669689628	0.00180466285022531	mirMAP	-0.251234878838157	5.37520689325609e-05		NA	NA	NA
hsa-miR-16-5p	PHACTR2	0.749619098384047	4.11649450706988e-06	-1.68321027518053	5.96237179238673e-21	miRNATAP	-0.10486832771568	0.0481735493465043		NA	NA	NA
hsa-miR-16-5p	PHLDB2	0.749619098384047	4.11649450706988e-06	-1.88290505989836	3.04266129032257e-12	miRNAWalker2_validate	-0.226869868044625	0.00371373129227853		NA	NA	NA
hsa-miR-16-5p	PHLPP2	0.749619098384047	4.11649450706988e-06	-0.55665406122771	0.000302384294043539	MirTarget;miRNATAP	-0.171697758945455	8.05570171842825e-05		NA	NA	NA
hsa-miR-16-5p	PID1	0.749619098384047	4.11649450706988e-06	-2.47680619803646	3.58452931681931e-15	MirTarget;miRNATAP	-0.30787155441926	0.000786602107907968		NA	NA	NA
hsa-miR-16-5p	PIK3R1	0.749619098384047	4.11649450706988e-06	-1.28526113405546	1.1596112892202e-14	MirTarget	-0.14663084031301	0.00245632583144358		NA	NA	NA
hsa-miR-16-5p	PITPNM3	0.749619098384047	4.11649450706988e-06	-0.614969996179847	0.020011396679978	MirTarget	-0.288611286283997	0.000109059291337765		NA	NA	NA
hsa-miR-16-5p	PLA2G15	0.749619098384047	4.11649450706988e-06	-0.650094152830941	9.752479363073e-07	MirTarget;miRNATAP	-0.120945441964767	0.00138376839574843		NA	NA	NA
hsa-miR-193b-3p	PLCH1	1.10444771306846	0.000822888533401377	0.0197909204054305	0.944806339717227	miRNATAP	-0.223309114480194	1.11557852401549e-08		NA	NA	NA
hsa-miR-16-5p	PLD1	0.749619098384047	4.11649450706988e-06	-0.0927976741742502	0.632163857168506	MirTarget	-0.127895097556896	0.019546686618304		NA	NA	NA
hsa-miR-16-5p	PLEC	0.749619098384047	4.11649450706988e-06	0.199456108240575	0.368114660695693	miRNAWalker2_validate	-0.206856932432146	0.000930034705529966		NA	NA	NA
hsa-miR-16-5p	PLEKHA1	0.749619098384047	4.11649450706988e-06	-0.794952450631166	1.98101339273862e-07	MirTarget;miRNATAP	-0.164446006859244	0.000159641895963715		NA	NA	NA
hsa-miR-16-5p	PLEKHA5	0.749619098384047	4.11649450706988e-06	0.350015576620528	0.0566872788500898	MirTarget	-0.144850620563278	0.00526705779199767		NA	NA	NA
hsa-miR-16-5p	PLSCR4	0.749619098384047	4.11649450706988e-06	-1.68148314100814	7.01935361254885e-16	miRNAWalker2_validate;MirTarget	-0.269933072537673	8.05178866740831e-06		NA	NA	NA
hsa-miR-16-5p	PLXDC1	0.749619098384047	4.11649450706988e-06	0.233626390859616	0.275410096112817	mirMAP	-0.156857009100127	0.00956044578753534		NA	NA	NA
hsa-miR-16-5p	PLXNA2	0.749619098384047	4.11649450706988e-06	-1.1615915565644	1.97317825006664e-05	MirTarget;miRNATAP	-0.187423127961383	0.0158500882591079		NA	NA	NA
hsa-miR-193b-3p	PLXNA2	1.10444771306846	0.000822888533401377	-1.1615915565644	1.97317825006664e-05	MirTarget	-0.174164632829158	4.09338784033467e-06		NA	NA	NA
hsa-miR-16-5p	PLXNC1	0.749619098384047	4.11649450706988e-06	-0.473030749626812	0.13158963398716	miRNATAP	-0.215105188845743	0.0154341259808773		NA	NA	NA
hsa-miR-193b-3p	PLXNC1	1.10444771306846	0.000822888533401377	-0.473030749626812	0.13158963398716	miRNAWalker2_validate;miRNATAP	-0.199354375878058	3.97407197374765e-06		NA	NA	NA
hsa-miR-16-5p	PMEPA1	0.749619098384047	4.11649450706988e-06	0.304394001071769	0.231381999994033	mirMAP	-0.372263959023342	1.65982471742852e-07		NA	NA	NA
hsa-miR-16-5p	PNMAL2	0.749619098384047	4.11649450706988e-06	-0.900305277488167	0.00182153755985784	MirTarget	-0.399014899757571	9.1150595956733e-07		NA	NA	NA
hsa-miR-16-5p	PNPLA6	0.749619098384047	4.11649450706988e-06	-1.57058552632445	4.02047105482656e-28	miRNAWalker2_validate;MirTarget;miRNATAP	-0.18173803680064	2.02863176994705e-05		NA	NA	NA
hsa-miR-16-5p	POLR2A	0.749619098384047	4.11649450706988e-06	-0.120629905311865	0.393331287764777	miRNAWalker2_validate	-0.113918740038343	0.00422465147904172		NA	NA	NA
hsa-miR-16-5p	PON2	0.749619098384047	4.11649450706988e-06	0.409610444795533	0.049352582929877	miRNAWalker2_validate	-0.121793047849845	0.0391502246469625		NA	NA	NA
hsa-miR-193b-3p	PRDM16	1.10444771306846	0.000822888533401377	-1.73309718408645	0.0003198093055403	mirMAP	-0.381438430431164	8.91003493530148e-09		NA	NA	NA
hsa-miR-16-5p	PRKAR2A	0.749619098384047	4.11649450706988e-06	-0.542111912815549	0.00820991566022701	miRNAWalker2_validate	-0.16233712492249	0.0052000527267614		NA	NA	NA
hsa-miR-193b-3p	PRKCA	1.10444771306846	0.000822888533401377	-0.189679589892687	0.471078192212991	miRNAWalker2_validate	-0.138487066621768	0.000138664149309437		NA	NA	NA
hsa-miR-16-5p	PRKG1	0.749619098384047	4.11649450706988e-06	-2.25433524061476	2.63202808294653e-12	miRNATAP	-0.562487937150872	9.52275941833596e-10		NA	NA	NA
hsa-miR-16-5p	PRNP	0.749619098384047	4.11649450706988e-06	-0.880476914948488	9.43327346142118e-07	miRNAWalker2_validate	-0.105584665838828	0.0399799572880095		NA	NA	NA
hsa-miR-193b-3p	PRNP	1.10444771306846	0.000822888533401377	-0.880476914948488	9.43327346142118e-07	miRNAWalker2_validate	-0.104680651028682	2.91662094123881e-05		NA	NA	NA
hsa-miR-16-5p	PRPF8	0.749619098384047	4.11649450706988e-06	-0.409957695890151	0.000853369789376417	miRNAWalker2_validate	-0.102571318067232	0.00319048778052053		NA	NA	NA
hsa-miR-16-5p	PRX	0.749619098384047	4.11649450706988e-06	-3.03883859563346	1.38620258400352e-27	mirMAP	-0.198905711976979	0.0178810903629755		NA	NA	NA
hsa-miR-16-5p	PSKH1	0.749619098384047	4.11649450706988e-06	-0.501646679898189	5.1333129690336e-06	MirTarget;miRNATAP	-0.107610364509011	0.000564406137857419		NA	NA	NA
hsa-miR-16-5p	PTGS1	0.749619098384047	4.11649450706988e-06	-0.977106995008052	5.92778940911097e-05	miRNAWalker2_validate	-0.274678971089479	6.86031334335783e-05		NA	NA	NA
hsa-miR-193b-3p	PTGS1	1.10444771306846	0.000822888533401377	-0.977106995008052	5.92778940911097e-05	miRNAWalker2_validate	-0.119107648626161	0.000445013629372873		NA	NA	NA
hsa-miR-16-5p	PTGS2	0.749619098384047	4.11649450706988e-06	-1.03369714758802	0.032296876715107	miRNAWalker2_validate;miRTarBase	-0.557741889577594	4.18248826425404e-05	24759835;25196524	MiR-16 and miR-101 levels do not correlate with COX-2 mRNA and protein levels;Artesunate induces apoptosis of bladder cancer cells by miR 16 regulation of COX 2 expression; Cyclooxygenase-2 COX-2 and miR-16 expression levels were determined with real-time PCR; ART efficiently inhibited orthotopic tumor growth in the bladder cancer rat which is accompanied with an increase of miR-16 expression and a decrease of COX-2 expression; ART significantly increased miR-16 expression and decreased the expression of COX-2 and the production of PGE2; More importantly down-regulation of miR-16 expression could reverse the effect of ART on apoptosis and COX-2 expression in bladder cells; In conclusion ART can elicit an anti-tumor effect against bladder cancer by up-regulation of miR-16 expression which resulted in the decrease of COX-2 expression and PGE2 production	;	liver cancer;bladder cancer
hsa-miR-16-5p	PTPN14	0.749619098384047	4.11649450706988e-06	-0.653551756267118	0.000637504682800457	MirTarget	-0.169742550921382	0.00176282076248393		NA	NA	NA
hsa-miR-16-5p	PTPRD	0.749619098384047	4.11649450706988e-06	-1.66030131903573	9.3195371074918e-08	miRNATAP	-0.368776988025342	3.23092091991983e-05		NA	NA	NA
hsa-miR-193b-3p	PTPRG	1.10444771306846	0.000822888533401377	-1.35345134348378	1.05687439659409e-07	miRNAWalker2_validate	-0.253488766061265	4.15923134684596e-13		NA	NA	NA
hsa-miR-16-5p	PTPRJ	0.749619098384047	4.11649450706988e-06	-0.375949362929813	0.0268897810823598	miRNAWalker2_validate	-0.129985022700762	0.00681861832509501		NA	NA	NA
hsa-miR-16-5p	PTPRT	0.749619098384047	4.11649450706988e-06	-2.80936308516019	3.80378146944574e-05	miRNAWalker2_validate	-0.524095932526719	0.00706513815895987		NA	NA	NA
hsa-miR-193b-3p	RAB27B	1.10444771306846	0.000822888533401377	0.187821282537161	0.627213809595502	MirTarget	-0.124675983296958	0.0202176108100471		NA	NA	NA
hsa-miR-193b-3p	RAC2	1.10444771306846	0.000822888533401377	-0.656275624483639	0.00297441142612925	miRNAWalker2_validate	-0.112838589622127	0.000231783502607722		NA	NA	NA
hsa-miR-16-5p	RAPGEF2	0.749619098384047	4.11649450706988e-06	-0.844531219425732	2.45585277201692e-10	miRNATAP	-0.141111314367745	0.000226244342112299		NA	NA	NA
hsa-miR-16-5p	RARB	0.749619098384047	4.11649450706988e-06	-0.706433267199561	0.00250747501748745	miRNATAP	-0.163618173930965	0.0136902278178657		NA	NA	NA
hsa-miR-16-5p	RASEF	0.749619098384047	4.11649450706988e-06	-0.0575028286178059	0.842369321258612	MirTarget	-0.230358232648142	0.00478949172171118		NA	NA	NA
hsa-miR-16-5p	RASL12	0.749619098384047	4.11649450706988e-06	-1.62969516969514	4.53332334684975e-13	miRNATAP	-0.219857738333626	0.000748693804416644		NA	NA	NA
hsa-miR-193b-3p	RASSF3	1.10444771306846	0.000822888533401377	-1.17064705626146	2.41605858463315e-09	miRNAWalker2_validate	-0.115633064677281	2.67533873540696e-05		NA	NA	NA
hsa-miR-193b-3p	RASSF5	1.10444771306846	0.000822888533401377	-0.762232040461735	2.73165460783976e-05	miRNAWalker2_validate	-0.177636947666694	8.04618692951266e-13		NA	NA	NA
hsa-miR-16-5p	RASSF8	0.749619098384047	4.11649450706988e-06	-1.79427432100023	3.30914182856082e-11	miRNATAP	-0.160959211808507	0.0399511595539199		NA	NA	NA
hsa-miR-16-5p	RBMS3	0.749619098384047	4.11649450706988e-06	-2.00226158386017	2.53710901023109e-11	miRNAWalker2_validate	-0.299744125050846	0.000537866064319767		NA	NA	NA
hsa-miR-16-5p	RECK	0.749619098384047	4.11649450706988e-06	-1.89897239930422	2.77224959500889e-19	miRNAWalker2_validate;miRNATAP	-0.248050304294242	6.34823906349764e-05	24852767	Aberrant expression level of miR-16 could suppress cell apoptosis while promote growth by regulating RECK and SOX6 which play important roles in the pathogenesis of ESCC		esophageal cancer
hsa-miR-16-5p	RET	0.749619098384047	4.11649450706988e-06	0.664782678642024	0.219288598940884	MirTarget;miRNATAP	-0.336236523153661	0.0282829081535503		NA	NA	NA
hsa-miR-16-5p	RGS22	0.749619098384047	4.11649450706988e-06	-2.93084427272334	2.4860183430889e-08	MirTarget	-0.323840303852086	0.0323369822091007		NA	NA	NA
hsa-miR-193b-3p	RHBDL3	1.10444771306846	0.000822888533401377	0.182774751860313	0.667248150908699	mirMAP	-0.140624212324503	0.0171690011348557		NA	NA	NA
hsa-miR-16-5p	RNF111	0.749619098384047	4.11649450706988e-06	-0.144180020656917	0.166411228244684	miRNAWalker2_validate;miRNATAP	-0.106309180133655	0.000273738361329198		NA	NA	NA
hsa-miR-16-5p	RNF43	0.749619098384047	4.11649450706988e-06	0.946327763824975	0.000219056740926585	MirTarget;miRNATAP	-0.163517138479037	0.0249660642209874		NA	NA	NA
hsa-miR-16-5p	ROR1	0.749619098384047	4.11649450706988e-06	-2.44635991699964	2.47189577870697e-13	miRNATAP	-0.272392155202666	0.00503353167460708		NA	NA	NA
hsa-miR-193b-3p	RORA	1.10444771306846	0.000822888533401377	-1.38443392547041	3.0515491681973e-10	miRNATAP	-0.135211130225499	1.2205100274702e-05		NA	NA	NA
hsa-miR-16-5p	RPH3AL	0.749619098384047	4.11649450706988e-06	-0.411148146217784	0.0912879262725756	miRNAWalker2_validate;MirTarget	-0.153331681358468	0.0261697837057436		NA	NA	NA
hsa-miR-193b-3p	RPS6KA2	1.10444771306846	0.000822888533401377	-1.04343331479045	1.62125928478786e-06	mirMAP	-0.126899545109533	2.89329618031281e-05		NA	NA	NA
hsa-miR-16-5p	RPS6KA3	0.749619098384047	4.11649450706988e-06	-0.054195404659354	0.708624881834648	miRNAWalker2_validate;MirTarget;miRNATAP	-0.165220770211374	4.86739262441925e-05		NA	NA	NA
hsa-miR-16-5p	RREB1	0.749619098384047	4.11649450706988e-06	0.0938559408741524	0.508511563384193	miRNATAP	-0.115449534199812	0.0038903722782544		NA	NA	NA
hsa-miR-16-5p	RSPO3	0.749619098384047	4.11649450706988e-06	-1.66375652226303	0.000140095171166556	MirTarget	-0.293233934652912	0.0185650913376485		NA	NA	NA
hsa-miR-193b-3p	RTKN2	1.10444771306846	0.000822888533401377	-4.23491297660768	6.74970506814765e-38	miRNAWalker2_validate	-0.176244618010672	0.000377311327396714		NA	NA	NA
hsa-miR-16-5p	RUNX1T1	0.749619098384047	4.11649450706988e-06	-1.82449256960527	3.90438288864204e-08	miRNAWalker2_validate;miRNATAP	-0.379664342711661	6.30642561514297e-05		NA	NA	NA
hsa-miR-193b-3p	RUNX1T1	1.10444771306846	0.000822888533401377	-1.82449256960527	3.90438288864204e-08	miRNATAP	-0.15569540891797	0.000851671309002835		NA	NA	NA
hsa-miR-16-5p	SAMD4A	0.749619098384047	4.11649450706988e-06	-1.27089348106065	2.91371609129609e-07	MirTarget	-0.234959621424434	0.000908861763359249		NA	NA	NA
hsa-miR-16-5p	SARM1	0.749619098384047	4.11649450706988e-06	-0.405662930586768	0.0257936493279576	mirMAP	-0.235514082088605	4.04921990059063e-06		NA	NA	NA
hsa-miR-16-5p	SCAMP5	0.749619098384047	4.11649450706988e-06	0.931351824858884	2.33010818877274e-05	mirMAP	-0.123396062748152	0.0496727789900566		NA	NA	NA
hsa-miR-16-5p	SCN2B	0.749619098384047	4.11649450706988e-06	-2.82021622286963	5.5334153862572e-12	mirMAP	-0.653586611347948	2.39244055968455e-08		NA	NA	NA
hsa-miR-16-5p	SCN4B	0.749619098384047	4.11649450706988e-06	-3.52378113696723	1.6864982583357e-23	miRNATAP	-0.467912359371185	7.27335739546764e-06		NA	NA	NA
hsa-miR-193b-3p	SDK2	1.10444771306846	0.000822888533401377	-0.844674083445059	0.0362673290489697	mirMAP	-0.171655699710612	0.00217656335702994		NA	NA	NA
hsa-miR-16-5p	SEL1L3	0.749619098384047	4.11649450706988e-06	0.57902176370524	0.000297812771356055	MirTarget	-0.128303340721162	0.00475055197113196		NA	NA	NA
hsa-miR-16-5p	SEMA3D	0.749619098384047	4.11649450706988e-06	-2.03263697588585	1.72473869928323e-07	MirTarget;miRNATAP	-0.366518105745663	0.000990917253606864		NA	NA	NA
hsa-miR-16-5p	SEMA5B	0.749619098384047	4.11649450706988e-06	0.283079777553037	0.419202307888543	MirTarget	-0.199824885411333	0.0440383243489637		NA	NA	NA
hsa-miR-16-5p	SEMA6D	0.749619098384047	4.11649450706988e-06	-2.80890333405802	1.12819674911885e-16	miRNATAP	-0.305392454430502	0.00207066503589246		NA	NA	NA
hsa-miR-16-5p	SEPT11	0.749619098384047	4.11649450706988e-06	-0.532598764843805	0.00107499183696739	MirTarget	-0.229886821761218	5.05732890197589e-07		NA	NA	NA
hsa-miR-16-5p	SERINC5	0.749619098384047	4.11649450706988e-06	-0.84294982118	0.00110034241982281	miRNAWalker2_validate	-0.284480844564955	9.87740636374945e-05		NA	NA	NA
hsa-miR-16-5p	SERPINB5	0.749619098384047	4.11649450706988e-06	2.17868757983461	0.00821990364902627	miRNAWalker2_validate	-0.483004938451021	0.0392580302454714		NA	NA	NA
hsa-miR-16-5p	SERPINE2	0.749619098384047	4.11649450706988e-06	0.568200017257809	0.0484367988596067	miRNAWalker2_validate	-0.200354717776468	0.0140305659827471		NA	NA	NA
hsa-miR-16-5p	SGCA	0.749619098384047	4.11649450706988e-06	-2.95941738646283	4.22289317248823e-13	MirTarget	-0.513701055423322	1.3194700065339e-05		NA	NA	NA
hsa-miR-16-5p	SGCD	0.749619098384047	4.11649450706988e-06	-1.50580144752869	5.97211906870455e-07	miRNATAP	-0.564667363944171	2.57343464581567e-11		NA	NA	NA
hsa-miR-16-5p	SH3PXD2B	0.749619098384047	4.11649450706988e-06	0.506639855504243	0.0154323108344532	mirMAP	-0.23815291949991	5.35041423721846e-05		NA	NA	NA
hsa-miR-16-5p	SHE	0.749619098384047	4.11649450706988e-06	-1.80013257760198	4.19344113029621e-06	mirMAP	-0.258396473408037	0.020965414064682		NA	NA	NA
hsa-miR-16-5p	SHROOM4	0.749619098384047	4.11649450706988e-06	-2.05663813992051	1.67658777305673e-13	miRNATAP	-0.318192193457443	8.13178081035194e-05		NA	NA	NA
hsa-miR-16-5p	SIDT2	0.749619098384047	4.11649450706988e-06	-1.2145586707932	5.81422161988479e-19	miRNATAP	-0.201729419129385	3.7928041957447e-07		NA	NA	NA
hsa-miR-16-5p	SIPA1L2	0.749619098384047	4.11649450706988e-06	-0.130992350270012	0.618771821146824	miRNAWalker2_validate;miRNATAP	-0.238917145960482	0.00129156233977984		NA	NA	NA
hsa-miR-16-5p	SKI	0.749619098384047	4.11649450706988e-06	-0.735047154029438	2.74103842517755e-08	MirTarget;miRNATAP	-0.180623480432468	1.51357158182238e-06		NA	NA	NA
hsa-miR-16-5p	SLC12A2	0.749619098384047	4.11649450706988e-06	0.19831419992694	0.449617189365851	miRNAWalker2_validate;MirTarget;miRNATAP	-0.289800732838613	8.59132139166587e-05		NA	NA	NA
hsa-miR-16-5p	SLC20A2	0.749619098384047	4.11649450706988e-06	-0.0817225860388868	0.679073250552629	miRNATAP	-0.118625000200421	0.0336408828460197		NA	NA	NA
hsa-miR-16-5p	SLC22A23	0.749619098384047	4.11649450706988e-06	-0.229916406100437	0.396353636858778	mirMAP	-0.193558301195835	0.0115528479184229		NA	NA	NA
hsa-miR-16-5p	SLC24A3	0.749619098384047	4.11649450706988e-06	-1.74142988680362	1.22358505102969e-07	miRNATAP	-0.595556048736544	1.33665513340599e-10		NA	NA	NA
hsa-miR-16-5p	SLC30A1	0.749619098384047	4.11649450706988e-06	0.48819549154425	0.00325772121325937	miRNAWalker2_validate	-0.132122353617872	0.00493752065736596		NA	NA	NA
hsa-miR-16-5p	SLC38A2	0.749619098384047	4.11649450706988e-06	-0.41201471205683	0.0105310210788705	miRNAWalker2_validate	-0.116094721544583	0.0109057054338508		NA	NA	NA
hsa-miR-16-5p	SLC38A5	0.749619098384047	4.11649450706988e-06	-0.990269722425781	0.000456049591359518	miRNAWalker2_validate	-0.200307290230804	0.0127004552949203		NA	NA	NA
hsa-miR-16-5p	SLC39A14	0.749619098384047	4.11649450706988e-06	0.3112660848419	0.144979904125944	miRNAWalker2_validate	-0.148458918899102	0.013977784754003		NA	NA	NA
hsa-miR-16-5p	SLC41A2	0.749619098384047	4.11649450706988e-06	0.785755470978635	0.0004224509265384	MirTarget	-0.127402544166776	0.0446774678035468		NA	NA	NA
hsa-miR-16-5p	SLC44A2	0.749619098384047	4.11649450706988e-06	-1.00571272952544	1.11779789606436e-16	mirMAP	-0.15979952401932	5.48686901760327e-06		NA	NA	NA
hsa-miR-16-5p	SLC4A4	0.749619098384047	4.11649450706988e-06	-1.38989899422976	0.000391987423522994	MirTarget;miRNATAP	-0.39069513780976	0.000444221170290871		NA	NA	NA
hsa-miR-16-5p	SLC5A3	0.749619098384047	4.11649450706988e-06	0.908460348379878	1.7896106467656e-05	miRNATAP	-0.155872674339461	0.00985907361823703		NA	NA	NA
hsa-miR-16-5p	SLC9A6	0.749619098384047	4.11649450706988e-06	-0.22278594887585	0.0657926158596923	miRNAWalker2_validate;MirTarget;miRNATAP	-0.112779603428533	0.000934169580249153		NA	NA	NA
hsa-miR-193b-3p	SLCO2A1	1.10444771306846	0.000822888533401377	-2.10235399487962	4.79343250186066e-12	miRNATAP	-0.192662211476589	7.27142647748672e-06		NA	NA	NA
hsa-miR-16-5p	SMAD3	0.749619098384047	4.11649450706988e-06	-0.104935015261858	0.513761397736816	MirTarget	-0.134568029960143	0.00296658337663515		NA	NA	NA
hsa-miR-16-5p	SMAD7	0.749619098384047	4.11649450706988e-06	-1.03334261220629	1.40098151909512e-11	miRNAWalker2_validate;MirTarget;miRNATAP	-0.146063396266522	0.000921870129280765		NA	NA	NA
hsa-miR-16-5p	SMPD1	0.749619098384047	4.11649450706988e-06	-0.486744938453821	0.000468962181012471	MirTarget	-0.130019790831889	0.000964070818471959		NA	NA	NA
hsa-miR-16-5p	SMURF1	0.749619098384047	4.11649450706988e-06	0.287563823129877	0.0397877028584235	MirTarget;miRNATAP	-0.113332994079076	0.00409703841491275		NA	NA	NA
hsa-miR-193b-3p	SNRK	1.10444771306846	0.000822888533401377	-1.22533314113389	3.97626958191335e-25	miRNAWalker2_validate	-0.103414550824716	1.22761452790105e-09		NA	NA	NA
hsa-miR-193b-3p	SNX18	1.10444771306846	0.000822888533401377	-0.215921071339985	0.165622857107174	miRNAWalker2_validate	-0.138741468574679	5.52838264305169e-11		NA	NA	NA
hsa-miR-16-5p	SOCS5	0.749619098384047	4.11649450706988e-06	-0.44143597114066	3.96474821502192e-05	miRNAWalker2_validate	-0.105960110768254	0.000489401778731672		NA	NA	NA
hsa-miR-193b-3p	SORCS2	1.10444771306846	0.000822888533401377	-1.43763126803471	0.00173888808713995	mirMAP	-0.335037311865185	1.2016975079962e-07		NA	NA	NA
hsa-miR-16-5p	SOX5	0.749619098384047	4.11649450706988e-06	-2.5492927879103	4.38349601252352e-14	miRNATAP	-0.237113874872741	0.0159862909076291		NA	NA	NA
hsa-miR-16-5p	SOX6	0.749619098384047	4.11649450706988e-06	-0.979926723135707	0.00981448848082569	MirTarget;miRNATAP	-0.32168429433904	0.00277514872896049	24852767	Aberrant expression level of miR-16 could suppress cell apoptosis while promote growth by regulating RECK and SOX6 which play important roles in the pathogenesis of ESCC		esophageal cancer
hsa-miR-193b-3p	SP4	1.10444771306846	0.000822888533401377	-0.0201738378428624	0.903549162541233	MirTarget	-0.107290462234631	2.68389997640034e-06		NA	NA	NA
hsa-miR-193b-3p	SPAG9	1.10444771306846	0.000822888533401377	-0.405143174419088	0.00524938705949926	miRNAWalker2_validate	-0.101172238265992	3.99524411309096e-07		NA	NA	NA
hsa-miR-193b-3p	SPATA13	1.10444771306846	0.000822888533401377	-0.793539686470286	0.000287646299267864	MirTarget	-0.111798274387553	0.000238561671283659		NA	NA	NA
hsa-miR-16-5p	SPEN	0.749619098384047	4.11649450706988e-06	-0.249316434710057	0.0507985101024194	miRNAWalker2_validate;MirTarget;miRNATAP	-0.108671128666087	0.00252579033852895		NA	NA	NA
hsa-miR-16-5p	SPRED1	0.749619098384047	4.11649450706988e-06	-0.494311600962025	0.0048335448827958	miRNAWalker2_validate;miRNATAP	-0.179254688409174	0.00029696785778991		NA	NA	NA
hsa-miR-16-5p	SPRY4	0.749619098384047	4.11649450706988e-06	-1.26334554012998	3.25375042707985e-08	miRNATAP	-0.274131538144085	2.64489336223491e-05		NA	NA	NA
hsa-miR-16-5p	SPRYD3	0.749619098384047	4.11649450706988e-06	-0.485098166363754	1.38646475829586e-05	miRNAWalker2_validate;MirTarget;miRNATAP	-0.201775668521426	9.07353653069608e-11		NA	NA	NA
hsa-miR-16-5p	SPSB4	0.749619098384047	4.11649450706988e-06	-1.54047160485992	1.94160929501082e-05	MirTarget;miRNATAP	-0.316485615457253	0.00207672734716967		NA	NA	NA
hsa-miR-193b-3p	SPTBN1	1.10444771306846	0.000822888533401377	-1.81822812989475	3.28142639207959e-29	miRNAWalker2_validate	-0.103215757343634	1.45398932694611e-05		NA	NA	NA
hsa-miR-16-5p	SSH1	0.749619098384047	4.11649450706988e-06	-0.451477299079478	0.000741175375192156	mirMAP	-0.186086362349497	7.34346010229085e-07		NA	NA	NA
hsa-miR-193b-3p	ST6GALNAC5	1.10444771306846	0.000822888533401377	-2.62879455179721	3.81050448046845e-16	MirTarget	-0.157448516021825	0.000660608957546662		NA	NA	NA
hsa-miR-16-5p	STON1	0.749619098384047	4.11649450706988e-06	-1.57570418834873	1.60585346644522e-12	MirTarget	-0.39913131068371	3.40926246957086e-10		NA	NA	NA
hsa-miR-16-5p	STXBP1	0.749619098384047	4.11649450706988e-06	-0.60819246830841	0.0108540127453225	MirTarget;miRNATAP	-0.152680006976263	0.0242002241780596		NA	NA	NA
hsa-miR-16-5p	SUFU	0.749619098384047	4.11649450706988e-06	-0.158741653760706	0.125523675629141	mirMAP	-0.121195569454969	2.91324692250613e-05		NA	NA	NA
hsa-miR-16-5p	SYDE1	0.749619098384047	4.11649450706988e-06	-1.12883462494007	5.74554997261285e-09	miRNATAP	-0.294584060435045	8.8361320653445e-08		NA	NA	NA
hsa-miR-16-5p	SYNE1	0.749619098384047	4.11649450706988e-06	-1.51993415510001	3.2888765494566e-09	MirTarget	-0.175515522465495	0.0176820814545314		NA	NA	NA
hsa-miR-16-5p	SYNPO	0.749619098384047	4.11649450706988e-06	-1.96248791236199	6.84613819072684e-22	mirMAP	-0.33221250100469	2.66260500117325e-08		NA	NA	NA
hsa-miR-16-5p	SYT11	0.749619098384047	4.11649450706988e-06	-1.09451836453881	7.53985874052456e-08	miRNAWalker2_validate	-0.118398734606125	0.0427731109227633		NA	NA	NA
hsa-miR-16-5p	SYT4	0.749619098384047	4.11649450706988e-06	-3.5163816540455	5.57670532042997e-08	MirTarget	-0.546585537704849	0.0032556907794161		NA	NA	NA
hsa-miR-16-5p	TACC1	0.749619098384047	4.11649450706988e-06	-2.05130402316217	4.79729930106458e-24	MirTarget	-0.233727921856588	0.000102317817066122		NA	NA	NA
hsa-miR-193b-3p	TACC1	1.10444771306846	0.000822888533401377	-2.05130402316217	4.79729930106458e-24	miRNAWalker2_validate	-0.175115883285793	1.98818393596302e-09		NA	NA	NA
hsa-miR-193b-3p	TAF9B	1.10444771306846	0.000822888533401377	-0.323574585470618	0.0144990479052404	miRNAWalker2_validate	-0.108497657989107	1.92823245664102e-09		NA	NA	NA
hsa-miR-16-5p	TAOK1	0.749619098384047	4.11649450706988e-06	-0.16111893285224	0.476174522942365	MirTarget;miRNATAP	-0.19131590424519	0.00271753362742668		NA	NA	NA
hsa-miR-193b-3p	TAOK3	1.10444771306846	0.000822888533401377	-0.43810473116311	0.000733770172402797	miRNAWalker2_validate	-0.10898395658295	8.21866391814071e-10		NA	NA	NA
hsa-miR-193b-3p	TAPT1	1.10444771306846	0.000822888533401377	-0.820063545839298	4.15175808417314e-07	MirTarget	-0.142634740394333	1.66747902104639e-10		NA	NA	NA
hsa-miR-16-5p	TBC1D16	0.749619098384047	4.11649450706988e-06	0.345597272254261	0.0587525206050741	MirTarget	-0.12521169215189	0.0155077929582284		NA	NA	NA
hsa-miR-16-5p	TEX261	0.749619098384047	4.11649450706988e-06	-0.0418625441555127	0.62406961320986	mirMAP	-0.106810887090939	6.99554213962461e-06		NA	NA	NA
hsa-miR-16-5p	TFAP2D	0.749619098384047	4.11649450706988e-06	2.71110460044099	0.000231491122060899	miRNATAP	-0.445091770835802	0.0340344582556831		NA	NA	NA
hsa-miR-193b-3p	TFCP2L1	1.10444771306846	0.000822888533401377	-0.0619294535495589	0.872377260386792	mirMAP	-0.107484606518451	0.044730324491136		NA	NA	NA
hsa-miR-193b-3p	TGFB2	1.10444771306846	0.000822888533401377	-1.54728695593794	7.69099073313309e-06	MirTarget;miRNATAP	-0.171701127106121	0.000381178774316089		NA	NA	NA
hsa-miR-16-5p	TGFBR3	0.749619098384047	4.11649450706988e-06	-3.00237515277085	4.40834583299503e-24	MirTarget;miRNATAP	-0.216664688747194	0.0143434557457065		NA	NA	NA
hsa-miR-193b-3p	TGFBR3	1.10444771306846	0.000822888533401377	-3.00237515277085	4.40834583299503e-24	miRNAWalker2_validate;MirTarget;miRNATAP	-0.229932194565447	8.29387328637064e-08		NA	NA	NA
hsa-miR-16-5p	TGOLN2	0.749619098384047	4.11649450706988e-06	-0.558416195393113	4.15934088855181e-06	miRNAWalker2_validate	-0.113170677975962	0.00102602404760329		NA	NA	NA
hsa-miR-16-5p	THSD4	0.749619098384047	4.11649450706988e-06	-1.50865067218173	2.24855229879e-09	MirTarget	-0.210684724268492	0.00370388937203261		NA	NA	NA
hsa-miR-16-5p	TIMP3	0.749619098384047	4.11649450706988e-06	-2.29631053711947	1.46430697909437e-17	miRNAWalker2_validate	-0.464147241369006	2.47873454503938e-09		NA	NA	NA
hsa-miR-193b-3p	TLE4	1.10444771306846	0.000822888533401377	-1.10987190193417	1.69879539502852e-07	miRNAWalker2_validate	-0.218693913669883	5.23284692125147e-14		NA	NA	NA
hsa-miR-16-5p	TLL1	0.749619098384047	4.11649450706988e-06	-2.10411717679539	4.78295684069891e-12	miRNATAP	-0.271382931645661	0.00206941815361255		NA	NA	NA
hsa-miR-16-5p	TMC7	0.749619098384047	4.11649450706988e-06	-0.668615332002322	0.0137084275312221	MirTarget	-0.217561819280908	0.00463802064633839		NA	NA	NA
hsa-miR-16-5p	TMEM100	0.749619098384047	4.11649450706988e-06	-4.7006922181647	1.53119031802875e-22	miRNAWalker2_validate;MirTarget	-0.320614099923013	0.0251270093782309		NA	NA	NA
hsa-miR-16-5p	TMEM104	0.749619098384047	4.11649450706988e-06	0.0557503982954817	0.637520357401263	mirMAP	-0.108889445786055	0.00105257723844919		NA	NA	NA
hsa-miR-16-5p	TMEM109	0.749619098384047	4.11649450706988e-06	-0.822426385978607	1.52206070015923e-14	miRNAWalker2_validate	-0.112283810534089	0.000285050985384734		NA	NA	NA
hsa-miR-16-5p	TMEM55A	0.749619098384047	4.11649450706988e-06	-0.503628696569831	0.00898301129241822	MirTarget	-0.169377564155774	0.00189661415850485		NA	NA	NA
hsa-miR-16-5p	TNFAIP8L3	0.749619098384047	4.11649450706988e-06	-1.5218669102825	2.15755709676929e-10	MirTarget	-0.206941656104898	0.00274151902155174		NA	NA	NA
hsa-miR-16-5p	TNK1	0.749619098384047	4.11649450706988e-06	0.465359961910381	0.00219238014285641	miRNAWalker2_validate	-0.109336374732789	0.011128839303572		NA	NA	NA
hsa-miR-16-5p	TNS3	0.749619098384047	4.11649450706988e-06	-1.2130009541022	1.59991857922078e-13	mirMAP	-0.203776791807646	1.74447629828614e-05		NA	NA	NA
hsa-miR-16-5p	TOM1L2	0.749619098384047	4.11649450706988e-06	-1.42026473507396	2.73798028997463e-18	mirMAP	-0.170081346632179	0.000359980445544358		NA	NA	NA
hsa-miR-16-5p	TPM2	0.749619098384047	4.11649450706988e-06	-0.325945705289001	0.170555063267889	MirTarget	-0.234252373433078	0.000477199582993802		NA	NA	NA
hsa-miR-193b-3p	TRAK2	1.10444771306846	0.000822888533401377	-0.851014457045884	1.02468318274346e-12	miRNAWalker2_validate	-0.108845353435657	5.8230895392531e-11		NA	NA	NA
hsa-miR-16-5p	TRAM1	0.749619098384047	4.11649450706988e-06	0.024873870625207	0.889647817884923	MirTarget	-0.163016777178575	0.0012455834254843		NA	NA	NA
hsa-miR-16-5p	TRIM44	0.749619098384047	4.11649450706988e-06	-0.498326644100839	0.00213955665680586	miRNAWalker2_validate	-0.122886392567704	0.00756714354475205		NA	NA	NA
hsa-miR-16-5p	TSPAN5	0.749619098384047	4.11649450706988e-06	0.442366789148323	0.106880080951868	MirTarget;miRNATAP	-0.215997914841634	0.00537226206398813		NA	NA	NA
hsa-miR-16-5p	TTC25	0.749619098384047	4.11649450706988e-06	-1.97521859653421	0.135779332535219	MirTarget	-0.757931246461247	0.0322021644662697		NA	NA	NA
hsa-miR-16-5p	UBXN2B	0.749619098384047	4.11649450706988e-06	0.0646219905847287	0.629753920380115	miRNAWalker2_validate	-0.102530200495429	0.00662589462857653		NA	NA	NA
hsa-miR-16-5p	UNC119B	0.749619098384047	4.11649450706988e-06	-0.713831092674094	2.17743125438357e-05	MirTarget	-0.118997874207433	0.0129995707215667		NA	NA	NA
hsa-miR-16-5p	USP12	0.749619098384047	4.11649450706988e-06	-1.07278863643269	1.83904836973154e-10	MirTarget;miRNATAP	-0.123758291373202	0.0107687294330741		NA	NA	NA
hsa-miR-16-5p	USP22	0.749619098384047	4.11649450706988e-06	-0.182961699809934	0.162990086142667	mirMAP	-0.125970315940526	0.000638102739589089		NA	NA	NA
hsa-miR-193b-3p	VAMP8	1.10444771306846	0.000822888533401377	-0.052813249208044	0.741578819242184	miRNAWalker2_validate	-0.104126261749498	2.17115907520491e-06		NA	NA	NA
hsa-miR-16-5p	VANGL1	0.749619098384047	4.11649450706988e-06	0.482522450244504	0.00121744978200244	mirMAP	-0.146020168541547	0.000536364284172832		NA	NA	NA
hsa-miR-16-5p	VASN	0.749619098384047	4.11649450706988e-06	-0.0572733083426931	0.825519643000495	miRNAWalker2_validate	-0.162202632798692	0.0272814542506233		NA	NA	NA
hsa-miR-16-5p	VCL	0.749619098384047	4.11649450706988e-06	-0.736048383378235	1.67285846550163e-06	miRNAWalker2_validate	-0.236830304846063	4.64015961096905e-08		NA	NA	NA
hsa-miR-16-5p	VPS13B	0.749619098384047	4.11649450706988e-06	-0.0561232521087103	0.666201217333163	mirMAP	-0.123530931603709	0.000728750442180614		NA	NA	NA
hsa-miR-16-5p	VWF	0.749619098384047	4.11649450706988e-06	-2.80037755667176	6.6145036112199e-24	mirMAP	-0.345255830894533	2.73135093957602e-05		NA	NA	NA
hsa-miR-16-5p	WDR47	0.749619098384047	4.11649450706988e-06	-0.677855133117753	3.66919584830427e-08	MirTarget;miRNATAP	-0.115516058319938	0.00101666540395674		NA	NA	NA
hsa-miR-16-5p	WISP1	0.749619098384047	4.11649450706988e-06	1.61421770591636	1.39528770321947e-07	MirTarget	-0.277552884178338	0.0015650167688235		NA	NA	NA
hsa-miR-16-5p	WNT5A	0.749619098384047	4.11649450706988e-06	-0.372121221213175	0.193057277928512	miRNAWalker2_validate	-0.268804385552065	0.000862585179250393		NA	NA	NA
hsa-miR-16-5p	WNT7A	0.749619098384047	4.11649450706988e-06	-4.45137691541241	9.35879470799359e-12	MirTarget	-0.548666659996717	0.00371402269827223		NA	NA	NA
hsa-miR-16-5p	WNT9A	0.749619098384047	4.11649450706988e-06	-1.70715193650801	1.03413487994031e-08	mirMAP	-0.26609532840731	0.00188366377751934		NA	NA	NA
hsa-miR-16-5p	WWC1	0.749619098384047	4.11649450706988e-06	-0.862637106674437	1.03990420322894e-06	MirTarget;miRNATAP	-0.102052538240089	0.0435330170204658		NA	NA	NA
hsa-miR-16-5p	XYLT1	0.749619098384047	4.11649450706988e-06	-0.0631449672028306	0.819527528344888	miRNAWalker2_validate;mirMAP	-0.479465485376769	4.48119213648603e-10		NA	NA	NA
hsa-miR-16-5p	ZBTB46	0.749619098384047	4.11649450706988e-06	-0.788827938657969	3.98051302684862e-05	MirTarget	-0.136326343017401	0.0127054510658833		NA	NA	NA
hsa-miR-16-5p	ZC3H12B	0.749619098384047	4.11649450706988e-06	-1.48767369908612	6.20369252469734e-12	miRNATAP	-0.252461201064645	5.12971995762802e-05		NA	NA	NA
hsa-miR-16-5p	ZFHX3	0.749619098384047	4.11649450706988e-06	-0.236175073775958	0.157995665090623	miRNAWalker2_validate;MirTarget;miRNATAP	-0.176893787677094	0.000170769979767209		NA	NA	NA
hsa-miR-16-5p	ZHX3	0.749619098384047	4.11649450706988e-06	-1.09617540983281	7.68051689405489e-15	mirMAP	-0.190936018189202	2.73826713476198e-06		NA	NA	NA
hsa-miR-16-5p	ZKSCAN1	0.749619098384047	4.11649450706988e-06	0.152515168368698	0.417713677219645	MirTarget;miRNATAP	-0.168507964868874	0.0014910444883844		NA	NA	NA
hsa-miR-16-5p	ZMAT3	0.749619098384047	4.11649450706988e-06	-0.318761613695159	0.0781412592604581	MirTarget	-0.108709889826041	0.0337989508558241		NA	NA	NA
hsa-miR-16-5p	ZMIZ1	0.749619098384047	4.11649450706988e-06	-0.842187632316551	3.85507879287997e-09	mirMAP	-0.181927807889752	8.11166107843566e-06		NA	NA	NA
hsa-miR-16-5p	ZNF275	0.749619098384047	4.11649450706988e-06	0.421446489325761	0.00250505558657776	MirTarget;miRNATAP	-0.126686098212098	0.00130799186774422		NA	NA	NA
hsa-miR-193b-3p	ZNF385B	1.10444771306846	0.000822888533401377	-3.47419980410087	7.7410828427632e-10	MirTarget	-0.435400203713844	3.49841065031037e-08		NA	NA	NA
hsa-miR-16-5p	ZNF423	0.749619098384047	4.11649450706988e-06	-2.25698605719176	1.47730613670829e-18	miRNATAP	-0.402071460687224	7.22691357757799e-08		NA	NA	NA
hsa-miR-16-5p	ZNF609	0.749619098384047	4.11649450706988e-06	-0.191085631263165	0.131028320926812	miRNATAP	-0.137820932881841	0.000104654335702819		NA	NA	NA
hsa-miR-16-5p	ZNF697	0.749619098384047	4.11649450706988e-06	0.0296257625014902	0.86856215591802	miRNATAP	-0.159849403433296	0.00152832225789524		NA	NA	NA
hsa-miR-16-5p	ZNF704	0.749619098384047	4.11649450706988e-06	-1.31546220210418	3.77547708108009e-06	MirTarget	-0.373884745811471	3.58973957553132e-06		NA	NA	NA
hsa-miR-193b-3p	ZNF823	1.10444771306846	0.000822888533401377	0.00254913815762059	0.985363004160483	miRNAWalker2_validate	-0.103653373266005	4.72752338303803e-08		NA	NA	NA
hsa-miR-16-5p	ZNF827	0.749619098384047	4.11649450706988e-06	0.0593685905890231	0.761929319824095	miRNAWalker2_validate	-0.137768953115682	0.0128027638039085		NA	NA	NA
hsa-miR-16-5p	ZNRF3	0.749619098384047	4.11649450706988e-06	-0.597752275417112	0.000467463649202618	miRNAWalker2_validate	-0.137447610955995	0.00459032638202854		NA	NA	NA
hsa-miR-16-5p	ZYX	0.749619098384047	4.11649450706988e-06	-0.919497236702092	6.75533258083569e-09	miRNAWalker2_validate;miRTarBase;miRNATAP	-0.149829032686696	0.000978664086489552		NA	NA	NA
hsa-miR-16-5p	ZZEF1	0.749619098384047	4.11649450706988e-06	-0.641294064778386	1.67119799410261e-06	miRNAWalker2_validate	-0.133325154758328	0.000463228724242081		NA	NA	NA