miRNA	gene	miRNA_log2FC	miRNA_pvalue	gene_log2FC	gene_pvalue	interactions	correlation_beta	correlation_pvalue	PMID	evidence	outcome	cancer
hsa-miR-125a-5p	CD276	-0.561874059994802	7.3931856356891e-13	1.1915111483872	1.38642383556914e-41	miRanda	-0.36630287196014	6.78670294241227e-08		NA	NA	NA
hsa-miR-29a-3p	CD276	-0.431613225927952	4.10166815070288e-08	1.1915111483872	1.38642383556914e-41	miRNAWalker2_validate;miRTarBase;MirTarget;miRNATAP	-0.160610603194702	0.0217071668930926		NA	NA	NA
hsa-miR-29c-3p	CD276	-0.238671318446745	0.0141475322347596	1.1915111483872	1.38642383556914e-41	MirTarget;miRNATAP	-0.249045026049738	1.12880110432146e-05	24577056	Identifying microRNAs regulating B7 H3 in breast cancer: the clinical impact of microRNA 29c		breast cancer
hsa-miR-149-5p	FOXM1	-1.95790336710741	8.46371715052367e-27	2.58237228443464	3.94274376219555e-50	miRNAWalker2_validate;MirTarget	-0.270648121818442	1.27403278575224e-06	23762558;25613903;27415661	miR 149 Inhibits Non Small Cell Lung Cancer Cells EMT by Targeting FOXM1; Overexpression of FOXM1 restored EMT process inhibited by miR-149;MicroRNA 149 suppresses colorectal cancer cell migration and invasion by directly targeting forkhead box transcription factor FOXM1; Gain- and loss - of - function assays indicated that miR-149 significantly inhibited growth migration and invasion of CRC cells by targeting FOXM1; Furthermore FOXM1 was significantly uiregulated in CRC tissues and inversely correlated with miR-149 expression;MicroRNA 149 Increases the Sensitivity of Colorectal Cancer Cells to 5 Fluorouracil by Targeting Forkhead Box Transcription Factor FOXM1; Previously we have shown that microRNA miR-149 suppresses the migration and invasion of colorectal cancer CRC cells by targeting forkhead box transcription factor FOXM1; The aim of this study is to investigate whether miR-149 targets FOXM1 to regulate the 5-FU resistance of CRC; Finally whether miR-149 regulates the 5-FU resistance of CRC cells by targeting the mammalian Forkhead Box M1 FOXM1 was investigated; In addition the luciferase assay indicated that miR-149 could bind to the 3'-UTR sequence of FOXM1 mRNA; The silencing of FOXM1 could mimic the effect of miR-149 upregulation on the 5-FU resistance of 5-FU-resistant CRC cells; Furthermore the expression of miR-149 in the 5-FU-responding CRC tissues was significantly higher than that in the non-responding tissues and inversely correlated with FOXM1 mRNA level; MiR-149 reverses the resistance of CRC cells to 5-FU by directly targeting FOXM1	;cell migration;drug resistance	lung squamous cell cancer;colorectal cancer;colorectal cancer
hsa-miR-200b-3p	FSCN1	-1.70383252137161	2.38979336321755e-30	1.40841436783423	1.2505824107599e-25	MirTarget;TargetScan	-0.436019095347309	4.12570131681726e-21	27356635	miR 200b inhibits migration and invasion in non small cell lung cancer cells via targeting FSCN1		lung squamous cell cancer
hsa-miR-200c-3p	FSCN1	-5.40303134829523	2.74173143360645e-94	1.40841436783423	1.2505824107599e-25	MirTarget	-0.206330089945663	9.95334281792107e-22		NA	NA	NA
hsa-miR-29a-5p	FSCN1	-0.519003718107105	1.03351148282116e-06	1.40841436783423	1.2505824107599e-25	miRNATAP	-0.249162506985101	0.000843139115142079		NA	NA	NA
hsa-miR-30a-5p	FSCN1	-0.778411951775343	2.73322451127932e-16	1.40841436783423	1.2505824107599e-25	miRNAWalker2_validate	-0.69300570256323	1.58824366552274e-19		NA	NA	NA
hsa-miR-429	FSCN1	-2.16569233119434	2.66862243626443e-37	1.40841436783423	1.2505824107599e-25	MirTarget;PITA;miRanda;miRNATAP	-0.347952516152661	3.39979811417681e-18	27042104	miR 429 functions as a tumor suppressor by targeting FSCN1 in gastric cancer cells; Fascin-1 FSCN1 was identified as one of the targets of miR-429 and knockdown of FSCN1 mimics the function of miR-429 overexpression; In conclusion miR-429 acts as a tumor suppressor by targeting FSCN1 suggesting that miR-429 and FSCN1 can both be potential therapeutic targets of GC		gastric cancer
hsa-miR-183-5p	ITGA5	-1.21596931064487	1.31473205758898e-08	2.04116263996683	7.34474138145585e-47	miRNAWalker2_validate	-0.168509641988799	4.28263649045998e-05		NA	NA	NA
hsa-miR-27b-3p	ITGA5	-0.699527231242518	1.07356023759234e-15	2.04116263996683	7.34474138145585e-47	miRNATAP	-0.665011188256571	8.42719111597212e-12		NA	NA	NA
hsa-miR-3065-3p	ITGA5	-1.64500070417457	9.57561660036697e-16	2.04116263996683	7.34474138145585e-47	miRNATAP	-0.336097070488892	8.38394013805882e-17		NA	NA	NA
hsa-miR-30a-5p	ITGA5	-0.778411951775343	2.73322451127932e-16	2.04116263996683	7.34474138145585e-47	miRNATAP	-0.963193438692052	8.11656677667882e-31		NA	NA	NA
hsa-miR-30c-5p	ITGA5	-1.08783070774238	2.02505402525786e-24	2.04116263996683	7.34474138145585e-47	miRNATAP	-0.80466770180918	2.23719209001784e-28		NA	NA	NA
hsa-miR-30d-5p	ITGA5	-0.202727675788184	0.00659067084745794	2.04116263996683	7.34474138145585e-47	miRNATAP	-0.832879085803553	2.90046596941365e-12		NA	NA	NA
hsa-miR-429	ITGA5	-2.16569233119434	2.66862243626443e-37	2.04116263996683	7.34474138145585e-47	miRNATAP	-0.500173657300576	8.56440818684276e-31		NA	NA	NA