miRNA gene miRNA_log2FC miRNA_pvalue gene_log2FC gene_pvalue interactions correlation_beta correlation_pvalue PMID evidence outcome cancer hsa-let-7a-5p E2F2 -0.0304750000000005 0.2544201287335 1.25491101439873 1.34486994652531e-12 miRNAWalker2_validate;miRTarBase;MirTarget;TargetScan -1.97858164350895 9.28149482786318e-05 20418948;25647078 MicroRNA let 7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2;Tumor suppressive microRNA let 7a inhibits cell proliferation via targeting of E2F2 in osteosarcoma cells; When let-7a was transfected into OS cell lines the expression of E2F2 in the cells was greatly suppressed suggesting that E2F2 is a target of miRNA-let-7a in OS cells ; prostate cancer;sarcoma hsa-let-7b-5p E2F2 -0.118293750000001 0.000772100831422107 1.25491101439873 1.34486994652531e-12 MirTarget -2.36608085838377 8.79191134852768e-11 NA NA NA hsa-let-7c-5p E2F2 -0.129896875000002 0.000858548240310724 1.25491101439873 1.34486994652531e-12 MirTarget -2.72274215979195 6.74825903727559e-18 NA NA NA hsa-let-7d-5p E2F2 -0.00841145833333479 0.75459096821833 1.25491101439873 1.34486994652531e-12 MirTarget -1.34108256638476 0.00845476863859243 NA NA NA hsa-let-7e-5p E2F2 -0.058575 0.0129021331137325 1.25491101439873 1.34486994652531e-12 MirTarget -2.58353161693722 5.65668292323766e-06 NA NA NA hsa-miR-125a-5p E2F2 -0.127755208333335 0.000138704165746353 1.25491101439873 1.34486994652531e-12 MirTarget -2.54853597252783 2.00342751711276e-11 NA NA NA hsa-miR-125b-5p E2F2 -0.187647916666668 1.01964050843717e-05 1.25491101439873 1.34486994652531e-12 miRNAWalker2_validate;miRTarBase;MirTarget;miRNATAP -2.92521016860087 6.18507147456215e-27 22999819 miR 125b regulates the proliferation of glioblastoma stem cells by targeting E2F2; This study demonstrated that miR-125b plays important roles in regulating the proliferation of GSCs by directly targeting E2F2 glioblastoma hsa-miR-130a-3p E2F2 -0.191241666666667 4.92233337068236e-06 1.25491101439873 1.34486994652531e-12 miRNATAP -1.56004095748561 4.27670534224481e-07 NA NA NA hsa-miR-204-5p E2F2 0.0144822916666668 0.790232989544289 1.25491101439873 1.34486994652531e-12 mirMAP -1.08500357484495 9.5333500263092e-06 NA NA NA hsa-miR-214-3p E2F2 -0.3224875 1.46111391717269e-10 1.25491101439873 1.34486994652531e-12 mirMAP -1.97230552740488 6.95908845269177e-17 NA NA NA hsa-miR-22-3p E2F2 -0.076525 0.0267118796232183 1.25491101439873 1.34486994652531e-12 miRNAWalker2_validate -2.6735123134466 4.98412298162075e-13 NA NA NA hsa-miR-26a-5p E2F2 -0.0802614583333372 6.57714639384254e-05 1.25491101439873 1.34486994652531e-12 miRNATAP -4.11998082781991 1.75389196865047e-10 26458859 MiR 26a enhances the sensitivity of gastric cancer cells to cisplatin by targeting NRAS and E2F2; Our results suggest that miR-26a can improve the sensitivity of GC cells to cisplatin-based chemotherapies through targeting NRAS and E2F2 and provide the first evidence of the potential utility of miR-26a as a sensitizer in chemotherapy for GC gastric cancer hsa-miR-26b-5p E2F2 -0.0469791666666701 0.0492766500438207 1.25491101439873 1.34486994652531e-12 miRNATAP -3.52479138620502 1.24264684304525e-10 NA NA NA hsa-miR-373-5p E2F2 -0.119583333333332 0.00146942333136967 1.25491101439873 1.34486994652531e-12 MirTarget -1.98319503569523 9.48124426437966e-09 NA NA NA hsa-miR-378a-3p E2F2 -0.134870833333334 0.0107938354842622 1.25491101439873 1.34486994652531e-12 MirTarget -1.4052770101504 1.10835996851322e-08 NA NA NA