miRNA gene miRNA_log2FC miRNA_pvalue gene_log2FC gene_pvalue interactions correlation_beta correlation_pvalue PMID evidence outcome cancer hsa-miR-140-5p ZHX1 0.0703636607466835 0.849968662093987 0.214023324704097 0.585711202317813 miRNATAP -0.144151120047069 0.00119029360645798 NA NA NA hsa-miR-186-5p ZHX1 0.145199897928531 0.797517603376996 0.214023324704097 0.585711202317813 mirMAP;miRNATAP -0.101146867955776 0.0341930579318718 NA NA NA hsa-miR-193a-3p ZHX1 -0.386637361847617 0.146286358085649 0.214023324704097 0.585711202317813 miRanda -0.105122776626575 0.000249944788776125 NA NA NA hsa-miR-199a-3p ZHX1 -0.788486532910886 0.325770472088725 0.214023324704097 0.585711202317813 PITA;miRNATAP -0.134061240459867 4.80373467667492e-06 25448600 MiR 199a 3p promotes gastric cancer progression by targeting ZHX1; In addition the expression of miR-199a-3p was inversely associated with that of ZHX1 in GC cell lines; Overexpression of miR-199a-3p in SGC-7901 cells inhibited ZHX1 expression while reduction in miR-199a-3p by inhibitors in NCI-N87 cells enhanced ZHX1 expression; Moreover restoring ZHX1 expression in SGC-7901/miR-199a-3p cells inhibited the cell proliferation induced by miR-199a-3p; Taken together these findings suggest that miR-199a-3p may function as a novel tumor promoter in GC and its oncogenic activity may involve the direct targeting and inhibition of ZHX1 progression gastric cancer hsa-miR-199b-3p ZHX1 -0.789151633183996 0.325144330589552 0.214023324704097 0.585711202317813 PITA;miRNATAP -0.133830966164019 4.91317709100368e-06 NA NA NA hsa-miR-338-3p ZHX1 -0.328701129742737 0.590176728236619 0.214023324704097 0.585711202317813 miRanda -0.105474658774629 0.000320813927345366 NA NA NA hsa-miR-497-5p ZHX1 -0.143930315402449 0.61973132929926 0.214023324704097 0.585711202317813 miRNATAP -0.121590536872013 0.000896479771896329 NA NA NA