miRNA	gene	miRNA_log2FC	miRNA_pvalue	gene_log2FC	gene_pvalue	interactions	correlation_beta	correlation_pvalue	PMID	evidence	outcome	cancer
hsa-let-7b-5p	AIFM1	-0.189422992330471	0.651878220048983	0.566138522069976	0.105763268412712	miRNATAP	-0.161261245245166	0.000699421266431265		NA	NA	NA
hsa-miR-106b-5p	AKT3	2.80565545918114	1.14547999022566e-09	-3.32677676487603	1.45486698220293e-05	miRNATAP	-0.411504731855899	9.49650030459631e-06		NA	NA	NA
hsa-miR-142-3p	AKT3	4.35304505457969	3.10014573651358e-10	-3.32677676487603	1.45486698220293e-05	miRanda	-0.161022651130634	0.00933730307368185		NA	NA	NA
hsa-miR-15a-5p	AKT3	2.0535411006904	1.91108976398046e-06	-3.32677676487603	1.45486698220293e-05	miRNAWalker2_validate;miRTarBase;miRNATAP	-0.374578960806042	0.000213935533400346		NA	NA	NA
hsa-miR-15b-5p	AKT3	3.32329949959268	8.40210501034588e-13	-3.32677676487603	1.45486698220293e-05	miRNATAP	-0.254367737995205	0.00570754876367863		NA	NA	NA
hsa-miR-16-5p	AKT3	2.93575808220754	2.15436817162977e-10	-3.32677676487603	1.45486698220293e-05	miRNAWalker2_validate;miRTarBase;miRNATAP	-0.309870666150618	0.000864570425925272		NA	NA	NA
hsa-miR-29b-3p	AKT3	0.666547117072858	0.234055379278093	-3.32677676487603	1.45486698220293e-05	miRNATAP	-0.283935483475042	0.000311340903637634	26512921	MicroRNA 29B mir 29b regulates the Warburg effect in ovarian cancer by targeting AKT2 and AKT3		ovarian cancer
hsa-miR-3065-5p	AKT3	2.14185373842821	0.0609400502269891	-3.32677676487603	1.45486698220293e-05	mirMAP	-0.221762461081726	2.87831776854007e-06		NA	NA	NA
hsa-miR-362-3p	AKT3	0.679952485897744	0.226148468488576	-3.32677676487603	1.45486698220293e-05	miRanda	-0.254988730314174	0.00123561088951897		NA	NA	NA
hsa-miR-501-3p	AKT3	1.72239979688923	0.0075900263732748	-3.32677676487603	1.45486698220293e-05	miRNATAP	-0.18288683695833	0.00732967244086728		NA	NA	NA
hsa-miR-93-5p	AKT3	2.65964181833033	2.58315947526774e-08	-3.32677676487603	1.45486698220293e-05	miRNATAP	-0.334744595445174	0.000214241376596223		NA	NA	NA
hsa-miR-155-5p	APAF1	2.81443182173772	7.42530504828797e-05	0.351537995191827	0.33130839684909	miRNAWalker2_validate	-0.105119871128062	0.000202319072259625	22996741;26877850	MiR 155 inhibits the sensitivity of lung cancer cells to cisplatin via negative regulation of Apaf 1 expression; The objective of this study is to verify the hypothesis based on the results of bioinformatics analysis that miR-155 modulates cellular apoptosis and DNA damage through the regulation of Apaf-1 and is thus involved in the development and progression of lung cancer; First we measured the expression of miR-155 and the Apaf-1 protein in lung cancer tissues; The results showed that expression of miR-155 was significantly higher in lung cancer tissues than in paracancerous and normal tissues; whereas Apaf-1 expression was lower in the lung cancerous tissues; The results showed that relative to controls the silencing of miR-155 resulted in elevated expression of the Apaf-1 protein whereas Apaf-1 mRNA levels remained unchanged; Both the silencing of miR-155 and the overexpression Apaf-1 greatly increased the sensitivity of A549 cells to cisplatin treatment as evidenced by elevated rates of apoptosis and DNA damage; Furthermore dual-transfection of A549 cells with miR-155 siRNA and Apaf-1 siRNA resulted in the attenuation of apoptosis and DNA damage;Also increase in the transcript level of APAF-1 and CASP-9 after downregulation of miR-21 and miR-155 might indicate that these genes were targeted by aforementioned miRNAs in T47D cells	progression;	lung cancer;breast cancer
hsa-miR-23a-3p	APAF1	0.925125296618358	0.0127293543936914	0.351537995191827	0.33130839684909	miRNATAP	-0.249229585742285	6.24449355106243e-06	24992592;24249161	Luciferase assay was performed to verify a putative target site of miR-23a in the 3'-UTR of apoptosis protease activating factor 1 APAF1 mRNA; The expression levels of miR-23a and APAF1 in CRC cell lines SW480 and SW620 and clinical samples were assessed using reverse transcription-quantitative real-time PCR RT-qPCR and Western blot; Moreover miR-23a up-regulation was coupled with APAF1 down-regulation in CRC tissue samples;We found that the expression of miR-23a was increased and the level of apoptosis-activating factor-1 APAF-1 was decreased in 5-FU-treated colon cancer cells compared to untreated cells; APAF-1 as a target gene of miR-23a was identified and miR-23a antisense-induced increase in the activation of caspase-9 was observed	;	colorectal cancer;colorectal cancer
hsa-miR-23b-3p	APAF1	-0.581135273821923	0.190478897170459	0.351537995191827	0.33130839684909	miRNATAP	-0.161636616309506	0.000480979993890262		NA	NA	NA
hsa-miR-27a-3p	APAF1	1.76094007417453	0.000216137556256765	0.351537995191827	0.33130839684909	miRNATAP	-0.178590051704588	2.61315263276561e-05		NA	NA	NA
hsa-miR-27b-3p	APAF1	-0.0929089601968123	0.85847352206581	0.351537995191827	0.33130839684909	miRNATAP	-0.157888261033241	5.61389496165659e-05		NA	NA	NA
hsa-miR-590-3p	APAF1	2.35429565068338	2.79601879608564e-06	0.351537995191827	0.33130839684909	PITA;miRanda;mirMAP;miRNATAP	-0.117753147962954	0.00340114353110643		NA	NA	NA
hsa-miR-708-3p	APAF1	0.781444321399141	0.290645825716608	0.351537995191827	0.33130839684909	mirMAP	-0.116215085120532	2.19939409004865e-05		NA	NA	NA
hsa-miR-203a-3p	ATM	6.35084246337388	7.89944323347948e-08	-0.658961239426083	0.11688259993407	MirTarget	-0.10711538788314	2.54510630277939e-08	24145123;27542403	miR 203 induces oxaliplatin resistance in colorectal cancer cells by negatively regulating ATM kinase; In silico analysis identified ataxia telangiectasia mutated ATM a primary mediator of the DNA damage response as a potential target of miR-203; Using TCGA database we identified a significant reverse correlation of miR-203 and ATM expression in CRC tissues; We validated ATM as a bona fide target of miR-203 in CRC cells; Mutation of the putative miR-203 binding site in the 3' untranslated region 3'UTR of the ATM mRNA abolished the inhibitory effect of miR-203 on ATM;MiR 203 inhibits tumor invasion and metastasis in gastric cancer by ATM; Our results showed that miR-203 was significantly downregulated in gastric cancer tissues and cells while ataxia telangiectasia mutated kinase ATM was upregulated in gastric cancer tissues and cells and was directly regulated by miR-203; ATM knockdown phenocopied the effect of miR-203 overexpression	drug resistance;metastasis	colorectal cancer;gastric cancer
hsa-miR-27a-5p	ATM	1.44543293228138	0.039420863458837	-0.658961239426083	0.11688259993407	MirTarget	-0.118013745915902	0.000461560887135157		NA	NA	NA
hsa-miR-30e-3p	ATM	-0.0362193022195196	0.932577027239525	-0.658961239426083	0.11688259993407	mirMAP	-0.157523794415466	0.00510124349387628		NA	NA	NA
hsa-miR-339-5p	ATM	1.23326828594484	0.0307501214818698	-0.658961239426083	0.11688259993407	miRanda	-0.155925656284305	0.000170742871820193		NA	NA	NA
hsa-miR-590-5p	ATM	1.51400888103768	0.0023888567923017	-0.658961239426083	0.11688259993407	mirMAP	-0.134411712770607	0.00484636149427119		NA	NA	NA
hsa-miR-16-2-3p	BCL2	3.79845098071094	1.49120139344659e-13	-3.06316187948847	1.08810932834372e-05	mirMAP	-0.198780086628007	0.00813011841160033		NA	NA	NA
hsa-miR-16-5p	BCL2	2.93575808220754	2.15436817162977e-10	-3.06316187948847	1.08810932834372e-05	miRNAWalker2_validate;miRTarBase	-0.272628063312585	0.00124978896318138	21336967;24447552;18449891;25435430;24598659;18931683;22966344;25623762	P glycoprotein enhances radiation induced apoptotic cell death through the regulation of miR 16 and Bcl 2 expressions in hepatocellular carcinoma cells; RHepG2 cells the multidrug resistant subline of human hepatocellular carcinoma HepG2 cells expressed higher levels of Pgp as well as miR-16 and lower level of Bcl-2 than the parental cells; On the other hand ectopic mdr1 expression enhanced radiation-induced apoptosis in HepG2 cells SK-HEP-1 cells MiHa cells and furthermore induced miR-16 and suppressed its target gene Bcl-2 in HepG2 cells; Moreover the enhancement effects of Pgp and miR-16 on radiation-induced apoptosis were counteracted by overexpression of Bcl-2;To study the expression of miR-16 and bcl-2 in T lymphoblastic lymphoma/leukemia T-LBL/ALL and its relationship to prognosis; The relationship of miR-16 and bcl-2 was significantP = 0.042χ2 = 4.147; The relationship of miR-16 and bcl-2 might suggested that gene regulation may be influenced by them;miR 15b and miR 16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells; The downregulation of miR-15b and miR-16 in SGC7901/VCR cells was concurrent with the upregulation of Bcl-2 protein; Taken together our findings suggest that miR-15b and miR-16 could play a role in the development of MDR in gastric cancer cells at least in part by modulation of apoptosis via targeting BCL2;We demonstrated that anti-apoptotic protein Bcl-2 was directly targeted miR-16 in paclitaxel resistant lung cancer cells; Combined overexpression of miR-16 and miR-17 greatly reduced Beclin-1 and Bcl-2 expressions respectively; miR-17 overexpression reduced cytoprotective autophagy by targeting Beclin-1 whereas overexpression of miR-16 potentiated paclitaxel induced apoptotic cell death by inhibiting anti-apoptotic protein Bcl-2;The miR-16 expression correlated with BCL-2 protein r = 0.51 P < 0.05;MicroRNAs miRNAs are noncoding small RNAs that repress protein translation by targeting specific messenger RNAs miR-15a and miR-16-1 act as putative tumor suppressors by targeting the oncogene BCL2;The overall objective of our investigation was to assess whether miRNA-16 miR-16 is involved in the regulation of critical genes such as BCL2 that control the sensitivity of pancreatic cancer cells to apoptosis; This study showed that the ectopic overexpression of miR-16 may be therapeutically beneficial as is evidenced by impaired cell survival with concomitant attenuation of anti-apoptotic protein Bcl-2; Moreover the luciferase reporter assay suggested that miR-16 post-transcriptionally regulates Bcl-2 expression in pancreatic cancer cells through the target sites of the 3' untranslated region of this gene;miR 15a and miR 16 modulate drug resistance by targeting bcl 2 in human colon cancer cells; To investigate the reversal effect of targeted modulation of bcl-2 expression by miR-15a and miR-16 on drug resistance of human colon cancer cells	;worse prognosis;drug resistance;;;;poor survival;drug resistance	liver cancer;lymphoma;gastric cancer;lung cancer;lymphoma;prostate cancer;pancreatic cancer;colon cancer
hsa-miR-192-5p	BCL2	1.77716187978541	0.113485496183047	-3.06316187948847	1.08810932834372e-05	miRNAWalker2_validate	-0.12938914604432	0.00025104427176319	26550150	MicroRNA 192 regulates chemo resistance of lung adenocarcinoma for gemcitabine and cisplatin combined therapy by targeting Bcl 2; In this paper we try to test whether miR-192 regulates chemo-resistance in human carcinoma A549 mice model by targeting Bcl-2; MTT assay real-time RT-PCR western blotting assay were used to investigate miR-192 expression levels cell viability ratio and Bcl-2 protein expression levels; Bcl-2 mRNA and protein expression levels up-regulated in miR-192 inhibitor treated tumor; Bcl-2 is a key regulator for miR-192 related chemotherapy resistance; In this study we demonstrate that miR-192 regulates chemoresistance for gemcitabine and cisplatin combined chemotherapy in human adenocarcinoma lung cancer A549 cells and Bcl-2 is the target of miR-192	drug resistance	lung cancer
hsa-miR-200a-5p	BCL2	6.52092140839401	5.73108242597059e-22	-3.06316187948847	1.08810932834372e-05	mirMAP	-0.195494336988318	0.000366255804733623		NA	NA	NA
hsa-miR-200b-5p	BCL2	6.81954246537908	6.31100593281326e-24	-3.06316187948847	1.08810932834372e-05	mirMAP	-0.203388603979853	0.000189900674957038		NA	NA	NA
hsa-miR-200c-3p	BCL2	6.47012025883743	2.64500707716408e-26	-3.06316187948847	1.08810932834372e-05	miRNAWalker2_validate;miRTarBase;mirMAP	-0.20320611228092	0.000726337324039896		NA	NA	NA
hsa-miR-21-5p	BCL2	2.65163477806992	6.72089787690756e-16	-3.06316187948847	1.08810932834372e-05	miRNAWalker2_validate;miRTarBase	-0.480047476048455	4.4710057406991e-05	21468550;25994220;25381586;26555418;23359184;22964582;21376256	BCL-2 up-regulation could be achieved by miR-21 overexpression which prevented T24 cells from apoptosis induced by doxorubicin; Furthermore the miR-21 induced BCL-2 up-regulation could be cancelled by the PI3K inhibitor LY294002;Meanwhile miR-21 loss reduced STAT3 and Bcl-2 activation causing an increase in the apoptosis of tumour cells in CAC mice;Changes in the sensitivity of osteosarcoma cells to CDDP were examined after transfection with miR-21 mimics or anti-miR-21 or bcl-2 siRNA in combination with CDDP;The expression of Bax Bcl-2 and miR-21 in parental and paclitaxel-resistant cells was detected by RT-PCR and Western blotting;Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR 21 regulation of BCL 2 expression; We also used Western blot to measure BCL-2 protein levels after down-regulation of miR-21 expression; Besides down-regulation of miR-21 expression can inhibit BCL-2 expression in PANC-1 CFPAC-1 and MIA Paca-2 cells; Over-expression of miR-21 expression can reverse down-regulation of BCL-2 expression and apoptosis induced by resveratrol; In this study we demonstrated that the effect of resveratrol on apoptosis is due to inhibiting miR-21 regulation of BCL-2 expression;Tumors harvested from these lungs have elevated levels of oncogenic miRNAs miR-21 and miR-155; are deficient for p53-regulated miRNAs; and have heightened expression of miR-34 target genes such as Met and Bcl-2;Bcl 2 upregulation induced by miR 21 via a direct interaction is associated with apoptosis and chemoresistance in MIA PaCa 2 pancreatic cancer cells; However the roles and mechanisms of miRNA miR-21 in regulation of Bcl-2 in pancreatic cancer remain to be elucidated; Then luciferase activity was observed after miR-21 mimics and pRL-TK plasmids containing wild-type and mutant 3'UTRs of Bcl-2 mRNA were co-transfected; Cells transfected with miR-21 inhibitor revealed an opposite trend. There was a significant increase in luciferase activity in the cells transfected with the wild-type pRL-TK plasmid in contrast to those transfected with the mutant one indicating that miR-21 promotes Bcl-2 expression by binding directly to the 3'UTR of Bcl-2 mRNA; Upregulation of Bcl-2 directly induced by miR-21 is associated with apoptosis chemoresistance and proliferation of MIA PaCa-2 pancreatic cancer cells	;;;;;;drug resistance	bladder cancer;colorectal cancer;sarcoma;breast cancer;pancreatic cancer;lung cancer;pancreatic cancer
hsa-miR-215-5p	BCL2	3.66990923176752	0.00294614570694381	-3.06316187948847	1.08810932834372e-05	miRNAWalker2_validate	-0.141357634568995	9.14425263109844e-06		NA	NA	NA
hsa-miR-24-2-5p	BCL2	2.06986947133452	5.98496897647448e-05	-3.06316187948847	1.08810932834372e-05	miRNAWalker2_validate;miRTarBase	-0.362853470345382	1.94710618153458e-06		NA	NA	NA
hsa-miR-3065-5p	BCL2	2.14185373842821	0.0609400502269891	-3.06316187948847	1.08810932834372e-05	mirMAP	-0.167248667776853	0.000110489568744755		NA	NA	NA
hsa-miR-338-5p	BCL2	-0.108304629897487	0.894675560494607	-3.06316187948847	1.08810932834372e-05	PITA	-0.15384518087035	0.00172699574421937		NA	NA	NA
hsa-miR-33b-5p	BCL2	4.77891217497671	1.33695107675057e-08	-3.06316187948847	1.08810932834372e-05	miRTarBase;mirMAP	-0.121788561427641	0.00899184402309845		NA	NA	NA
hsa-miR-365a-3p	BCL2	0.25545896241765	0.654320504621012	-3.06316187948847	1.08810932834372e-05	miRNAWalker2_validate;miRTarBase	-0.394898362577108	1.10607300598646e-08		NA	NA	NA
hsa-miR-429	BCL2	6.39965293994036	1.96920201593608e-18	-3.06316187948847	1.08810932834372e-05	miRNAWalker2_validate;miRTarBase;PITA;mirMAP	-0.160807368066818	0.00180825818683377	23999873;26513239;26511969	MiR 429 up regulation induces apoptosis and suppresses invasion by targeting Bcl 2 and SP 1 in esophageal carcinoma; Subsequent Western blotting and luciferase reporter assays showed that miR-429 can bind to putative binding sites within the Bcl-2 and SP1 mRNA 3' untranslated regions UTRs to reduce their expression; Up-regulation of miR-429 inhibits invasion and promotes apoptosis in EC cells by targeting Bcl-2 and SP1; Our findings suggest that Bcl-2 and SP1 may serve as major targets of miR-429;MiR 429 Induces Gastric Carcinoma Cell Apoptosis Through Bcl 2; Here we studied the levels of miR-429 and anti-apoptotic protein Bcl-2 in GC specimens; We performed bioinformatics analyses and used luciferase-reporter assay to analyze the relationship between miR-429 and Bcl-2 in GC cells; MiR-429 levels were significantly decreased and Bcl-2 levels were significantly increased in GC specimens compared to the paired adjacent non-tumor gastric tissue; Moreover the levels of miR-429 and Bcl-2 inversely correlated in GC specimens; Bioinformatics analyses showed that miR-429 targeted the 3'-UTR of Bcl-2 mRNA to inhibit its translation which was confirmed by luciferase-reporter assay;MiR 429 induces apoptosis of glioblastoma cell through Bcl 2; Here we analyzed the levels of miR-429 and anti-apoptotic protein Bcl-2 in GBM specimens; We combined bioinformatics analyses and luciferase reporter assay to determine the relationship between miR-429 and Bcl-2 in GBM cells; We found that miR-429 levels were significantly decreased and Bcl-2 levels were significantly increased in GBM specimens compared to the paired adjacent non-tumor brain tissue; Moreover the levels of miR-429 and Bcl-2 inversely correlated; MiR-429 targeted the 3'-UTR of Bcl-2 mRNA to inhibit its translation	;;	esophageal cancer;gastric cancer;glioblastoma
hsa-miR-582-5p	BCL2	0.685177900016753	0.447761540297692	-3.06316187948847	1.08810932834372e-05	PITA	-0.134818080111642	0.00230990489507861		NA	NA	NA
hsa-miR-629-5p	BCL2	1.57164125641392	0.0115716388531198	-3.06316187948847	1.08810932834372e-05	mirMAP	-0.253306211867568	7.16586879182246e-05		NA	NA	NA
hsa-miR-7-5p	BCL2	3.59831747997243	0.000676336260217879	-3.06316187948847	1.08810932834372e-05	miRNAWalker2_validate;miRTarBase;mirMAP	-0.1242073018915	0.00724600894737725	26464649;25862909;21750649	Western blotting was used to evaluate the effect of miR-7 on Bcl2 in A549 and H460 cells; Moreover subsequent experiments showed that BCL-2 was downregulated by miR-7 at both transcriptional and translational levels; This study further extends the biological role of miR-7 in NSCLC A549 and H460 cells and identifies BCL-2 as a novel target possibly involved in miR-7-mediated growth suppression and apoptosis induction of NSCLC cells;miR-7 overexpression correlated with diminished BCL2 expression but there was no relationship between miR-7 and EGFR expression neither in tumour samples nor in the cell lines; Of the two postulated miR-7 target genes we examined BCL2 but not EGFR seems to be a possible miR-7 target in OC;Bioinformatics predictions revealed a potential binding site of miR-7 on 3'UTR of BCL-2 and it was further confirmed by luciferase assay; Moreover subsequent experiments showed that BCL-2 was downregulated by miR-7 at both transcriptional and translational levels; These results suggest that miR-7 regulates the expression of BCL-2 through direct 3'UTR interactions	;;	lung squamous cell cancer;ovarian cancer;lung squamous cell cancer
hsa-miR-342-3p	BCL2L1	1.31107714473009	0.0207211910724662	0.387849298249143	0.372559860651897	PITA;miRanda;miRNATAP	-0.126863966321354	0.00344426702929298		NA	NA	NA
hsa-miR-24-1-5p	BIRC3	-0.638925193416348	0.236125310537158	0.151020658041541	0.885694929117284	MirTarget	-0.358268151050507	0.00120618170314208		NA	NA	NA
hsa-miR-491-5p	CAPN1	0.569358547192776	0.313310594748302	1.31250824709003	0.00019342035101578	miRanda	-0.146719227529871	4.56515860680285e-05		NA	NA	NA
hsa-miR-1468-5p	CAPN2	-1.63442718498426	0.00779372976116312	0.651486358651082	0.138715166460298	MirTarget	-0.20208968575975	4.78335198372869e-07		NA	NA	NA
hsa-miR-20a-3p	CAPN2	1.9920766549842	0.000624458530894697	0.651486358651082	0.138715166460298	MirTarget	-0.140475332643721	0.000931394416878954		NA	NA	NA
hsa-miR-421	CAPN2	1.97624148591545	0.000915838012451138	0.651486358651082	0.138715166460298	miRanda	-0.109203106517093	0.0088789695877179		NA	NA	NA
hsa-miR-125b-5p	CASP10	-2.01187572101832	0.00516480893645494	0.696594106032744	0.336705522947674	mirMAP	-0.153393011039	0.0069590481393416		NA	NA	NA
hsa-miR-361-5p	CASP10	0.00649167180664723	0.985202350239079	0.696594106032744	0.336705522947674	miRanda	-0.46185739017424	0.000107312796513352		NA	NA	NA
hsa-miR-532-5p	CASP10	-0.297424983759107	0.503934707453099	0.696594106032744	0.336705522947674	mirMAP	-0.467593826928243	3.69564958364264e-07		NA	NA	NA
hsa-miR-589-3p	CASP10	1.33205316880069	0.052632683806148	0.696594106032744	0.336705522947674	mirMAP	-0.229037416486941	0.00012648308689486		NA	NA	NA
hsa-miR-592	CASP10	2.80403350008555	0.0293520213681333	0.696594106032744	0.336705522947674	miRNATAP	-0.104832733343847	0.00729546473661119		NA	NA	NA
hsa-miR-744-3p	CASP10	1.08385719878174	0.131243679775541	0.696594106032744	0.336705522947674	mirMAP	-0.389147042180601	1.93568579672746e-12		NA	NA	NA
hsa-miR-361-5p	CASP7	0.00649167180664723	0.985202350239079	0.552586925970727	0.214980741147346	PITA;miRanda	-0.196491640269563	0.00761577874218848		NA	NA	NA
hsa-miR-125a-5p	CFLAR	-1.32352790615388	0.00714301627309467	0.10975680494869	0.785876903093292	miRanda	-0.126729197885069	0.00640094446943848		NA	NA	NA
hsa-miR-130b-3p	CFLAR	3.9204771543282	1.2714917955808e-11	0.10975680494869	0.785876903093292	mirMAP	-0.136933509317755	0.000311790699059756		NA	NA	NA
hsa-miR-301a-3p	CFLAR	1.99338115332667	0.000813358604963724	0.10975680494869	0.785876903093292	mirMAP	-0.142408816847749	0.000173112484747624		NA	NA	NA
hsa-miR-30b-3p	CFLAR	0.169674321578618	0.766080356926625	0.10975680494869	0.785876903093292	mirMAP	-0.159754908443129	6.83731029154175e-05		NA	NA	NA
hsa-miR-582-5p	CHP2	0.685177900016753	0.447761540297692	1.48109800587141	0.509563690322669	miRNATAP	-0.415938249783453	0.0031281915626761		NA	NA	NA
hsa-miR-15b-3p	CSF2RB	3.57530146629867	5.89922785773482e-11	-0.531949678174437	0.52469724338113	mirMAP	-0.243883163153962	0.00378871588753218		NA	NA	NA
hsa-miR-19b-3p	CSF2RB	1.67581705793313	0.000858910586302716	-0.531949678174437	0.52469724338113	MirTarget	-0.249978645254246	0.00793124384654011		NA	NA	NA
hsa-miR-30b-3p	CSF2RB	0.169674321578618	0.766080356926625	-0.531949678174437	0.52469724338113	MirTarget	-0.278521035137442	0.000870863627134223		NA	NA	NA
hsa-miR-365a-3p	DFFB	0.25545896241765	0.654320504621012	-0.125452270886234	0.736775154451074	MirTarget	-0.104776615460763	0.00471093454042319		NA	NA	NA
hsa-miR-130b-3p	ENDOD1	3.9204771543282	1.2714917955808e-11	-1.15080298333206	0.0185661445984158	MirTarget	-0.123811637273732	0.00768158978083829		NA	NA	NA
hsa-miR-181a-5p	ENDOD1	1.25558293560636	0.00748975499703878	-1.15080298333206	0.0185661445984158	MirTarget	-0.187411883595055	0.00155676708701448		NA	NA	NA
hsa-miR-181c-5p	ENDOD1	-0.302833440762172	0.537532549455539	-1.15080298333206	0.0185661445984158	MirTarget	-0.191406533855745	0.000752702169700885		NA	NA	NA
hsa-miR-19a-3p	ENDOD1	2.17020503944519	0.00122084653711062	-1.15080298333206	0.0185661445984158	mirMAP	-0.123622385321676	0.00260534190818447		NA	NA	NA
hsa-miR-19b-3p	ENDOD1	1.67581705793313	0.000858910586302716	-1.15080298333206	0.0185661445984158	mirMAP	-0.160391298766318	0.00360487948297533		NA	NA	NA
hsa-miR-200b-3p	ENDOD1	5.56167217794639	6.43540045061709e-16	-1.15080298333206	0.0185661445984158	TargetScan	-0.126814654390186	0.000916290413422611		NA	NA	NA
hsa-miR-26b-3p	ENDOD1	0.985177548213122	0.0351427970185971	-1.15080298333206	0.0185661445984158	mirMAP	-0.154240417208051	0.00986863139851759		NA	NA	NA
hsa-miR-301a-3p	ENDOD1	1.99338115332667	0.000813358604963724	-1.15080298333206	0.0185661445984158	MirTarget	-0.130559457956406	0.00488088631995514		NA	NA	NA
hsa-miR-3613-5p	ENDOD1	4.05007522786126	4.52786477176299e-14	-1.15080298333206	0.0185661445984158	MirTarget	-0.201855032650942	4.29102693515804e-05		NA	NA	NA
hsa-miR-362-3p	ENDOD1	0.679952485897744	0.226148468488576	-1.15080298333206	0.0185661445984158	miRanda	-0.182370207955287	0.000231966663699426		NA	NA	NA
hsa-miR-454-3p	ENDOD1	1.40269869979902	0.00366085847011367	-1.15080298333206	0.0185661445984158	MirTarget	-0.233643994119384	4.41462077769692e-05		NA	NA	NA
hsa-miR-589-5p	ENDOD1	1.55790780760302	0.000326340665093671	-1.15080298333206	0.0185661445984158	MirTarget	-0.177647132185528	0.00560274996532207		NA	NA	NA
hsa-miR-590-3p	ENDOD1	2.35429565068338	2.79601879608564e-06	-1.15080298333206	0.0185661445984158	miRanda	-0.21562284963162	7.2235803998372e-05		NA	NA	NA
hsa-miR-24-3p	EXOG	1.55853749533999	0.000524726461381821	-0.0602324359259732	0.858947815339452	MirTarget	-0.143003272289887	0.000748094007636054		NA	NA	NA
hsa-miR-106a-5p	FAS	3.98693608217557	9.37722470816656e-07	-0.344841531633832	0.589341195024639	miRNAWalker2_validate;miRTarBase	-0.140227807754695	0.00127753821199214	22431000;27142596	miR 106a is frequently upregulated in gastric cancer and inhibits the extrinsic apoptotic pathway by targeting FAS; Bioinformatic analysis combining with validation experiments identified FAS as a direct target of miR-106a; Moreover a significant inverse correlation was found between miR-106a and FAS expression not only in gastric cancer cell lines but also in gastric cancer specimens; Taken together these findings suggest that ectopicly overexpressed miR-106a may play an oncogenic role in gastric carcinogenesis and impair extrinsic apoptotic pathway through targeting FAS;Functional experiment ascertained that miR-106a interacted with FAS and mediated caspase3 pathway	tumorigenesis;	gastric cancer;gastric cancer
hsa-miR-361-5p	FAS	0.00649167180664723	0.985202350239079	-0.344841531633832	0.589341195024639	miRanda	-0.330419186265804	0.00171930259182594		NA	NA	NA
hsa-miR-590-5p	FAS	1.51400888103768	0.0023888567923017	-0.344841531633832	0.589341195024639	miRanda	-0.19807034795777	0.00636164081342142		NA	NA	NA
hsa-miR-199a-5p	FASLG	-1.24888110793613	0.0747755616523728	1.92790162472903	0.0908475849274605	miRanda	-0.398497989415625	1.31601874419318e-05		NA	NA	NA
hsa-miR-28-5p	FASLG	-0.815636722979196	0.0221199948901761	1.92790162472903	0.0908475849274605	miRanda	-0.57816364875664	0.00170836414115334		NA	NA	NA
hsa-miR-324-5p	FASLG	1.31253452379847	0.0116806680545163	1.92790162472903	0.0908475849274605	miRanda	-0.332106354222357	0.00772738622468345		NA	NA	NA
hsa-miR-92b-3p	FASLG	1.69303761469782	0.0103484911955574	1.92790162472903	0.0908475849274605	miRNATAP	-0.252529060131383	0.00986337973635399		NA	NA	NA
hsa-miR-151a-3p	IKBKB	0.373902859770645	0.376924505912903	0.104177496834708	0.718852918781577	miRNAWalker2_validate	-0.121270812981731	0.00180898875297091		NA	NA	NA
hsa-miR-339-5p	IKBKB	1.23326828594484	0.0307501214818698	0.104177496834708	0.718852918781577	miRanda	-0.112704791185609	7.01383121429463e-05		NA	NA	NA
hsa-miR-542-3p	IKBKB	-0.376147863244659	0.438002751207043	0.104177496834708	0.718852918781577	miRanda	-0.1114840138672	0.000952486304701064		NA	NA	NA
hsa-miR-125a-5p	IKBKG	-1.32352790615388	0.00714301627309467	0.217673245627403	0.541287587904691	miRanda	-0.110235437146931	0.00712043030373108		NA	NA	NA
hsa-miR-338-5p	IKBKG	-0.108304629897487	0.894675560494607	0.217673245627403	0.541287587904691	mirMAP	-0.107990652303128	1.00066234929907e-05		NA	NA	NA
hsa-miR-181c-5p	IL1A	-0.302833440762172	0.537532549455539	4.31599389135009	0.0104359859237567	MirTarget	-0.750864040262053	0.000127388155916292		NA	NA	NA
hsa-miR-191-5p	IL1A	1.58824208483839	0.000738859004053681	4.31599389135009	0.0104359859237567	miRNAWalker2_validate	-0.920302645458858	5.18012425368392e-06		NA	NA	NA
hsa-miR-200a-3p	IL1A	6.336081120041	4.024313571871e-16	4.31599389135009	0.0104359859237567	MirTarget	-0.461162168953321	7.32399186286365e-05		NA	NA	NA
hsa-miR-30a-5p	IL1A	-0.768430903969183	0.320487552854215	4.31599389135009	0.0104359859237567	MirTarget	-0.52318793715064	2.12283658834032e-05		NA	NA	NA
hsa-miR-532-5p	IL1A	-0.297424983759107	0.503934707453099	4.31599389135009	0.0104359859237567	MirTarget	-1.49939259880363	1.12516024441561e-12		NA	NA	NA
hsa-miR-17-3p	IL1R1	1.2477858204856	0.00186593270231258	-2.02737457884455	0.00137078637258843	mirMAP	-0.478550922210701	8.17349650316603e-08		NA	NA	NA
hsa-miR-335-3p	IL1R1	1.19503568251824	0.0938852560631551	-2.02737457884455	0.00137078637258843	mirMAP	-0.223081090533626	8.58843025959345e-06		NA	NA	NA
hsa-miR-106a-5p	IL1RAP	3.98693608217557	9.37722470816656e-07	1.81317515528315	0.0267244199977934	MirTarget	-0.218470157967721	9.0151667480019e-05		NA	NA	NA
hsa-miR-107	IL1RAP	1.49443409571439	0.000130594521065411	1.81317515528315	0.0267244199977934	miRanda	-0.363722797160927	0.00232718010564673		NA	NA	NA
hsa-miR-186-5p	IL1RAP	0.445443449112564	0.185447310527704	1.81317515528315	0.0267244199977934	mirMAP	-0.718403028369971	2.51603762712787e-07		NA	NA	NA
hsa-miR-192-5p	IL1RAP	1.77716187978541	0.113485496183047	1.81317515528315	0.0267244199977934	miRNAWalker2_validate	-0.252268654885249	3.56574127396124e-10		NA	NA	NA
hsa-miR-20b-5p	IL1RAP	4.5662923200279	4.75238200639144e-05	1.81317515528315	0.0267244199977934	MirTarget	-0.178160427060987	1.0452389681559e-05		NA	NA	NA
hsa-miR-215-5p	IL1RAP	3.66990923176752	0.00294614570694381	1.81317515528315	0.0267244199977934	miRNAWalker2_validate	-0.154148331658159	3.25348220932905e-05		NA	NA	NA
hsa-miR-301a-3p	IL1RAP	1.99338115332667	0.000813358604963724	1.81317515528315	0.0267244199977934	MirTarget	-0.237604716994952	0.00221832588789205		NA	NA	NA
hsa-miR-361-5p	IL1RAP	0.00649167180664723	0.985202350239079	1.81317515528315	0.0267244199977934	miRanda	-0.504621719246811	0.000189048746747028		NA	NA	NA
hsa-miR-362-3p	IL1RAP	0.679952485897744	0.226148468488576	1.81317515528315	0.0267244199977934	miRanda	-0.268765999532969	0.00124584358240993		NA	NA	NA
hsa-miR-375	IL1RAP	3.3784490463318	0.0449946294355695	1.81317515528315	0.0267244199977934	miRNAWalker2_validate;miRanda	-0.202285910594492	1.49808538529928e-14		NA	NA	NA
hsa-miR-7-1-3p	IL1RAP	1.43074343339835	0.00471215970502094	1.81317515528315	0.0267244199977934	MirTarget	-0.262830853426143	0.00426933865405271		NA	NA	NA
hsa-miR-93-5p	IL1RAP	2.65964181833033	2.58315947526774e-08	1.81317515528315	0.0267244199977934	MirTarget	-0.260712964664117	0.00654269721595287		NA	NA	NA
hsa-miR-335-5p	IRAK2	0.167216045757305	0.803897055331049	0.53992460937121	0.48745272926867	miRNAWalker2_validate	-0.232052126462868	0.00037873058269171		NA	NA	NA
hsa-miR-20a-3p	IRAK3	1.9920766549842	0.000624458530894697	-1.5911768648261	0.0608932642227986	mirMAP	-0.261465893520975	0.00147408885342381		NA	NA	NA
hsa-miR-3200-3p	IRAK3	2.3251191657063	0.0140310042534957	-1.5911768648261	0.0608932642227986	mirMAP	-0.154032322884487	0.00255901964782929		NA	NA	NA
hsa-miR-361-5p	IRAK3	0.00649167180664723	0.985202350239079	-1.5911768648261	0.0608932642227986	miRanda;mirMAP	-0.365282147434525	0.00952444469992107		NA	NA	NA
hsa-miR-421	IRAK3	1.97624148591545	0.000915838012451138	-1.5911768648261	0.0608932642227986	miRanda;mirMAP	-0.243149449692798	0.00257706348366609		NA	NA	NA
hsa-miR-429	IRAK3	6.39965293994036	1.96920201593608e-18	-1.5911768648261	0.0608932642227986	miRanda	-0.177229769626644	0.00434710987093182		NA	NA	NA
hsa-miR-501-5p	IRAK3	1.0411896821345	0.0777206709183552	-1.5911768648261	0.0608932642227986	mirMAP	-0.322048750119535	7.47349631798561e-05		NA	NA	NA
hsa-miR-660-5p	IRAK3	-0.0668683798854808	0.885250178390404	-1.5911768648261	0.0608932642227986	mirMAP	-0.331093437975956	0.0016025474932389		NA	NA	NA
hsa-miR-9-3p	IRAK3	1.69328215716742	0.125170982657059	-1.5911768648261	0.0608932642227986	mirMAP	-0.157203774120566	0.000355966379034606		NA	NA	NA
hsa-miR-92a-3p	IRAK3	1.87892405805529	1.27013821556583e-05	-1.5911768648261	0.0608932642227986	mirMAP	-0.317244142926089	0.00448492815917761		NA	NA	NA
hsa-miR-193a-3p	IRAK4	0.646392169474854	0.207134343676122	0.276224247443857	0.306973017403332	miRanda	-0.102433012412476	0.000571205505589283		NA	NA	NA
hsa-miR-17-5p	MAP3K14	2.3269271449522	2.13987445663942e-05	-0.572095255643433	0.232052277296526	MirTarget	-0.154710364889365	0.00157167780275142		NA	NA	NA
hsa-miR-345-5p	MAP3K14	2.77314563304336	4.34343702412489e-05	-0.572095255643433	0.232052277296526	MirTarget	-0.103524963377024	0.00878161781449097		NA	NA	NA
hsa-miR-429	MAP3K14	6.39965293994036	1.96920201593608e-18	-0.572095255643433	0.232052277296526	miRNATAP	-0.116936681153463	0.000784919148104685		NA	NA	NA
hsa-miR-93-5p	MAP3K14	2.65964181833033	2.58315947526774e-08	-0.572095255643433	0.232052277296526	MirTarget	-0.2276783161594	3.94079758590909e-05		NA	NA	NA
hsa-let-7g-5p	NGF	0.857251702023746	0.00647597344297273	-4.9479894848305	8.79599085267218e-05	MirTarget	-0.75463687244667	0.00128893578106286		NA	NA	NA
hsa-miR-429	NGF	6.39965293994036	1.96920201593608e-18	-4.9479894848305	8.79599085267218e-05	miRanda	-0.370250673166168	6.50680322666926e-05		NA	NA	NA
hsa-miR-148b-3p	PIK3CA	1.75622244535669	8.84414356040579e-08	0.514328426212782	0.248930105421785	miRNAWalker2_validate	-0.244141801200414	0.00147579635788138		NA	NA	NA
hsa-miR-186-5p	PIK3CA	0.445443449112564	0.185447310527704	0.514328426212782	0.248930105421785	mirMAP	-0.280960133798979	0.000232701716483115		NA	NA	NA
hsa-miR-29b-1-5p	PIK3CA	0.33698032160171	0.598092174563471	0.514328426212782	0.248930105421785	mirMAP	-0.12089066483943	0.00233700941849917		NA	NA	NA
hsa-miR-320b	PIK3CA	0.20205459771295	0.727216419960509	0.514328426212782	0.248930105421785	miRanda	-0.121444800770151	0.00550932456475504		NA	NA	NA
hsa-miR-335-5p	PIK3CA	0.167216045757305	0.803897055331049	0.514328426212782	0.248930105421785	miRNAWalker2_validate	-0.124494566731403	0.000883627732385134		NA	NA	NA
hsa-miR-338-5p	PIK3CA	-0.108304629897487	0.894675560494607	0.514328426212782	0.248930105421785	mirMAP	-0.108048495334147	0.00046563589386498		NA	NA	NA
hsa-miR-339-5p	PIK3CA	1.23326828594484	0.0307501214818698	0.514328426212782	0.248930105421785	miRanda	-0.13798173006655	0.00178425799549926		NA	NA	NA
hsa-miR-501-5p	PIK3CA	1.0411896821345	0.0777206709183552	0.514328426212782	0.248930105421785	mirMAP	-0.120904681333791	0.00473986403400753		NA	NA	NA
hsa-miR-130a-3p	PIK3CB	0.176861046122832	0.7577473016872	0.897158330473952	0.0125840363244796	miRNATAP	-0.116582529549782	0.00106378240800672		NA	NA	NA
hsa-miR-19b-3p	PIK3CB	1.67581705793313	0.000858910586302716	0.897158330473952	0.0125840363244796	miRNATAP	-0.110401307134748	0.00639042894521705		NA	NA	NA
hsa-miR-1468-5p	PIK3CD	-1.63442718498426	0.00779372976116312	0.0551399776366237	0.926564879247674	MirTarget	-0.153354934509346	0.00559561965869134		NA	NA	NA
hsa-miR-199a-5p	PIK3CD	-1.24888110793613	0.0747755616523728	0.0551399776366237	0.926564879247674	MirTarget;PITA;miRanda;miRNATAP	-0.160352223725155	0.000860262558034989		NA	NA	NA
hsa-miR-30d-5p	PIK3CD	0.302504510257496	0.380193536606962	0.0551399776366237	0.926564879247674	MirTarget;miRNATAP	-0.269704587228763	0.00722775970426478		NA	NA	NA
hsa-miR-3913-5p	PIK3CD	0.145645056779437	0.734844256690741	0.0551399776366237	0.926564879247674	mirMAP	-0.258109601835399	0.00117084989668902		NA	NA	NA
hsa-miR-335-3p	PIK3CG	1.19503568251824	0.0938852560631551	-0.156343505309127	0.848670326900117	mirMAP	-0.289128547018831	6.98940085423769e-06		NA	NA	NA
hsa-miR-16-2-3p	PIK3R1	3.79845098071094	1.49120139344659e-13	-1.85375256159008	0.0127438113463991	MirTarget	-0.220421111740374	0.0054973163518176		NA	NA	NA
hsa-miR-16-5p	PIK3R1	2.93575808220754	2.15436817162977e-10	-1.85375256159008	0.0127438113463991	MirTarget	-0.232718839097215	0.0094069232214411		NA	NA	NA
hsa-miR-17-5p	PIK3R1	2.3269271449522	2.13987445663942e-05	-1.85375256159008	0.0127438113463991	MirTarget;TargetScan;miRNATAP	-0.263550021803503	0.000561403048031031		NA	NA	NA
hsa-miR-200c-3p	PIK3R1	6.47012025883743	2.64500707716408e-26	-1.85375256159008	0.0127438113463991	mirMAP	-0.209884750055895	0.000971059963262446		NA	NA	NA
hsa-miR-29b-3p	PIK3R1	0.666547117072858	0.234055379278093	-1.85375256159008	0.0127438113463991	MirTarget;miRNATAP	-0.229458801110313	0.00247922380727846		NA	NA	NA
hsa-miR-3065-5p	PIK3R1	2.14185373842821	0.0609400502269891	-1.85375256159008	0.0127438113463991	MirTarget;mirMAP;miRNATAP	-0.136442762182432	0.00300321263691178		NA	NA	NA
hsa-miR-320c	PIK3R1	-0.10618808730545	0.854002814666472	-1.85375256159008	0.0127438113463991	miRNATAP	-0.237528056213487	0.00153215444016214		NA	NA	NA
hsa-miR-330-3p	PIK3R1	2.49094236945806	0.000129367003214715	-1.85375256159008	0.0127438113463991	MirTarget;PITA;miRNATAP	-0.222421511130143	0.000560333266659095		NA	NA	NA
hsa-miR-335-3p	PIK3R1	1.19503568251824	0.0938852560631551	-1.85375256159008	0.0127438113463991	mirMAP	-0.187424798668302	0.00154671007013318		NA	NA	NA
hsa-miR-338-5p	PIK3R1	-0.108304629897487	0.894675560494607	-1.85375256159008	0.0127438113463991	PITA	-0.149038254580324	0.00415133065382571		NA	NA	NA
hsa-miR-582-5p	PIK3R1	0.685177900016753	0.447761540297692	-1.85375256159008	0.0127438113463991	mirMAP	-0.168928206892885	0.000293205730117536		NA	NA	NA
hsa-miR-584-5p	PIK3R1	1.17912816682866	0.202862496863776	-1.85375256159008	0.0127438113463991	mirMAP	-0.264485629334745	3.0909574049315e-09		NA	NA	NA
hsa-miR-590-5p	PIK3R1	1.51400888103768	0.0023888567923017	-1.85375256159008	0.0127438113463991	MirTarget;PITA;miRanda;miRNATAP	-0.297003967343676	0.000452335914243657		NA	NA	NA
hsa-miR-629-3p	PIK3R1	3.48282157979573	4.9176538695908e-08	-1.85375256159008	0.0127438113463991	MirTarget	-0.21216292379107	0.00105654186835094		NA	NA	NA
hsa-miR-1271-5p	PIK3R3	0.212382644103427	0.742544160267329	-0.029728653396571	0.959330193755408	mirMAP	-0.151933011438603	0.00299533512999816		NA	NA	NA
hsa-miR-18a-3p	PIK3R3	3.64944956993027	7.20156641833731e-07	-0.029728653396571	0.959330193755408	miRNAWalker2_validate	-0.172437749406846	8.76134189601592e-05		NA	NA	NA
hsa-miR-222-5p	PIK3R3	2.52056758362407	0.00142010793166944	-0.029728653396571	0.959330193755408	mirMAP	-0.169591357898129	3.80520658072856e-05		NA	NA	NA
hsa-miR-29b-1-5p	PIK3R3	0.33698032160171	0.598092174563471	-0.029728653396571	0.959330193755408	mirMAP	-0.214703534793861	3.15537480066889e-05		NA	NA	NA
hsa-miR-330-3p	PIK3R3	2.49094236945806	0.000129367003214715	-0.029728653396571	0.959330193755408	MirTarget	-0.191183653307302	0.000135580399986553		NA	NA	NA
hsa-miR-330-5p	PIK3R3	2.25110496739954	0.000275527655397415	-0.029728653396571	0.959330193755408	miRanda	-0.158989578902319	0.00262587059425892		NA	NA	NA
hsa-miR-365a-3p	PIK3R3	0.25545896241765	0.654320504621012	-0.029728653396571	0.959330193755408	MirTarget	-0.330277583325266	6.38384266733533e-09		NA	NA	NA
hsa-miR-511-5p	PIK3R3	1.10428503984162	0.179276103915417	-0.029728653396571	0.959330193755408	MirTarget	-0.179185145111208	6.38466351145281e-06	25608840	MiR 511 inhibits growth and metastasis of human hepatocellular carcinoma cells by targeting PIK3R3; We further demonstrated that miR-511 suppressed HCC cell proliferation migration and invasion by repressing PIK3R3 expression	metastasis	liver cancer
hsa-miR-590-5p	PIK3R3	1.51400888103768	0.0023888567923017	-0.029728653396571	0.959330193755408	miRanda	-0.195493025557274	0.00311783468590026		NA	NA	NA
hsa-miR-125a-3p	PIK3R5	-0.0748960586927341	0.920735897434087	0.75811064163987	0.286920846128457	miRanda	-0.143772140191083	0.00747323319002246		NA	NA	NA
hsa-miR-125a-5p	PIK3R5	-1.32352790615388	0.00714301627309467	0.75811064163987	0.286920846128457	MirTarget;miRanda	-0.250957855170204	0.00223286885929377		NA	NA	NA
hsa-miR-182-5p	PIK3R5	5.86988712704738	1.22411588571584e-15	0.75811064163987	0.286920846128457	MirTarget	-0.25329203027594	9.2894340160784e-07		NA	NA	NA
hsa-let-7g-5p	PPP3CA	0.857251702023746	0.00647597344297273	-0.0994691469518081	0.767527156115313	miRNATAP	-0.161347150543761	0.00879795113322894		NA	NA	NA
hsa-let-7a-3p	PRKACB	0.82512001802525	0.0468122405194487	-1.46896806095161	0.00691161548744777	MirTarget;mirMAP;miRNATAP	-0.212227756129949	0.00484060334729975		NA	NA	NA
hsa-miR-141-3p	PRKACB	7.30474126597325	1.45115996357606e-24	-1.46896806095161	0.00691161548744777	MirTarget;TargetScan;miRNATAP	-0.179713976485568	5.50509722074074e-06		NA	NA	NA
hsa-miR-16-2-3p	PRKACB	3.79845098071094	1.49120139344659e-13	-1.46896806095161	0.00691161548744777	mirMAP	-0.256987391063205	7.64721558586313e-06		NA	NA	NA
hsa-miR-17-5p	PRKACB	2.3269271449522	2.13987445663942e-05	-1.46896806095161	0.00691161548744777	TargetScan	-0.147030961972885	0.00870649595844882		NA	NA	NA
hsa-miR-182-5p	PRKACB	5.86988712704738	1.22411588571584e-15	-1.46896806095161	0.00691161548744777	MirTarget;miRNATAP	-0.137741652786639	0.000572629355125557		NA	NA	NA
hsa-miR-183-5p	PRKACB	6.61903249270777	1.00958881445636e-16	-1.46896806095161	0.00691161548744777	MirTarget	-0.125680903296988	0.000602029705127091		NA	NA	NA
hsa-miR-18a-5p	PRKACB	3.90770175770219	9.15298615034137e-10	-1.46896806095161	0.00691161548744777	miRNATAP	-0.147626596716624	0.00172397395444837		NA	NA	NA
hsa-miR-193a-3p	PRKACB	0.646392169474854	0.207134343676122	-1.46896806095161	0.00691161548744777	miRanda	-0.257394862253127	1.9252355211219e-05		NA	NA	NA
hsa-miR-19a-3p	PRKACB	2.17020503944519	0.00122084653711062	-1.46896806095161	0.00691161548744777	MirTarget;miRNATAP	-0.131490327577289	0.0040920531186784		NA	NA	NA
hsa-miR-19b-3p	PRKACB	1.67581705793313	0.000858910586302716	-1.46896806095161	0.00691161548744777	miRNAWalker2_validate;MirTarget;miRNATAP	-0.191193316637283	0.00183404785527112		NA	NA	NA
hsa-miR-200a-3p	PRKACB	6.336081120041	4.024313571871e-16	-1.46896806095161	0.00691161548744777	MirTarget;miRNATAP	-0.104144124001908	0.00576356163422443		NA	NA	NA
hsa-miR-200c-3p	PRKACB	6.47012025883743	2.64500707716408e-26	-1.46896806095161	0.00691161548744777	MirTarget;miRNATAP	-0.145130591541329	0.00181365494045828		NA	NA	NA
hsa-miR-3065-5p	PRKACB	2.14185373842821	0.0609400502269891	-1.46896806095161	0.00691161548744777	MirTarget	-0.128827162641901	0.000116356569225078		NA	NA	NA
hsa-miR-429	PRKACB	6.39965293994036	1.96920201593608e-18	-1.46896806095161	0.00691161548744777	MirTarget;PITA;miRanda;miRNATAP	-0.108770954611392	0.00641118010678973		NA	NA	NA
hsa-miR-93-5p	PRKACB	2.65964181833033	2.58315947526774e-08	-1.46896806095161	0.00691161548744777	miRNAWalker2_validate	-0.1828758599464	0.00409856289818273		NA	NA	NA
hsa-miR-96-5p	PRKACB	5.62521466029286	1.54938806718028e-10	-1.46896806095161	0.00691161548744777	miRNATAP	-0.17033105097326	3.99524226143001e-05		NA	NA	NA
hsa-miR-186-5p	PRKAR1A	0.445443449112564	0.185447310527704	-1.01828820623811	0.001225821997322	mirMAP	-0.180144708459278	0.000892993033458124		NA	NA	NA
hsa-miR-25-3p	PRKAR1A	1.12623030168869	0.00311079344417173	-1.01828820623811	0.001225821997322	miRNAWalker2_validate	-0.137457165995076	0.00373320016478192		NA	NA	NA
hsa-miR-30e-5p	PRKAR1A	0.780047227271616	0.0346714425913016	-1.01828820623811	0.001225821997322	mirMAP	-0.195080535639843	6.48511031213636e-05		NA	NA	NA
hsa-miR-590-3p	PRKAR1A	2.35429565068338	2.79601879608564e-06	-1.01828820623811	0.001225821997322	miRanda;mirMAP	-0.117659255376238	0.000811435622796728		NA	NA	NA
hsa-miR-590-5p	PRKAR1A	1.51400888103768	0.0023888567923017	-1.01828820623811	0.001225821997322	miRanda	-0.10914100263527	0.00232969513055624		NA	NA	NA
hsa-let-7a-3p	PRKAR2A	0.82512001802525	0.0468122405194487	0.476694411438259	0.551908785996894	mirMAP	-0.301009578826657	0.00647099970354146		NA	NA	NA
hsa-miR-125a-5p	PRKAR2A	-1.32352790615388	0.00714301627309467	0.476694411438259	0.551908785996894	miRanda	-0.269844648912326	0.00350273799952414		NA	NA	NA
hsa-miR-155-5p	PRKAR2A	2.81443182173772	7.42530504828797e-05	0.476694411438259	0.551908785996894	miRNAWalker2_validate	-0.21708406345224	0.000566306153716087		NA	NA	NA
hsa-miR-26a-5p	PRKAR2A	-0.352368463397074	0.362040749917446	0.476694411438259	0.551908785996894	mirMAP	-0.334762860834375	0.00501415610057783		NA	NA	NA
hsa-miR-26b-5p	PRKAR2A	0.314414148564179	0.461628303578321	0.476694411438259	0.551908785996894	mirMAP	-0.286017162331329	0.00788651739787191		NA	NA	NA
hsa-miR-29a-5p	PRKAR2A	0.0748295222568571	0.884125894063293	0.476694411438259	0.551908785996894	mirMAP	-0.315640015483038	0.000372346869393992		NA	NA	NA
hsa-miR-320a	PRKAR2A	-0.912036444869976	0.0565555443926988	0.476694411438259	0.551908785996894	mirMAP	-0.268019149243362	0.00499308515469227		NA	NA	NA
hsa-miR-342-5p	PRKAR2A	1.3865615438184	0.0153598969109545	0.476694411438259	0.551908785996894	miRNATAP	-0.269573945336104	0.000654404755458937		NA	NA	NA
hsa-miR-3607-3p	PRKAR2A	1.38015131722213	0.0240067155694847	0.476694411438259	0.551908785996894	mirMAP	-0.244787916293228	0.000939419376053357		NA	NA	NA
hsa-let-7a-3p	PRKAR2B	0.82512001802525	0.0468122405194487	-2.78794723692538	0.0026756054188432	mirMAP	-0.490436382372777	0.000131692115153379		NA	NA	NA
hsa-let-7f-1-3p	PRKAR2B	1.61507869803314	0.00069342464777815	-2.78794723692538	0.0026756054188432	mirMAP	-0.590656604378212	7.69012984955533e-08		NA	NA	NA
hsa-miR-200c-3p	PRKAR2B	6.47012025883743	2.64500707716408e-26	-2.78794723692538	0.0026756054188432	miRNATAP	-0.232410940316261	0.00356398855766406		NA	NA	NA
hsa-miR-32-5p	PRKAR2B	2.93035124381469	5.00149131394151e-10	-2.78794723692538	0.0026756054188432	miRNATAP	-0.359735337701038	0.00104357271928938		NA	NA	NA
hsa-miR-590-3p	PRKAR2B	2.35429565068338	2.79601879608564e-06	-2.78794723692538	0.0026756054188432	miRNAWalker2_validate;miRanda	-0.336156932957071	0.00124725671489497		NA	NA	NA
hsa-miR-92a-3p	PRKAR2B	1.87892405805529	1.27013821556583e-05	-2.78794723692538	0.0026756054188432	miRNATAP	-0.399693388608365	0.00109215156585527		NA	NA	NA
hsa-miR-944	PRKAR2B	7.20925181386398	0.000823207457340648	-2.78794723692538	0.0026756054188432	mirMAP	-0.153211582863098	2.7267140771681e-07		NA	NA	NA
hsa-miR-130a-5p	PRKX	1.58028512890005	0.024346333013728	2.17507999383594	0.000704686070863552	mirMAP	-0.187730727746443	0.00038419514315305		NA	NA	NA
hsa-miR-148b-3p	PRKX	1.75622244535669	8.84414356040579e-08	2.17507999383594	0.000704686070863552	MirTarget	-0.306982570800927	0.00606517379097925		NA	NA	NA
hsa-miR-335-3p	PRKX	1.19503568251824	0.0938852560631551	2.17507999383594	0.000704686070863552	mirMAP	-0.162862473837577	0.00148982890472507		NA	NA	NA
hsa-miR-361-5p	TNF	0.00649167180664723	0.985202350239079	2.70587865709665	0.00827809785812044	miRanda	-0.699393715835311	3.55980064084335e-05		NA	NA	NA
hsa-miR-654-3p	TNF	-1.00320329950348	0.243908885746048	2.70587865709665	0.00827809785812044	miRNATAP	-0.184952039903252	0.006307888857058		NA	NA	NA
hsa-miR-340-5p	TNFRSF10B	1.41210478721579	0.00958612942879818	1.49454504792051	0.00242678998916782	miRNAWalker2_validate	-0.149759402379779	0.00368309518497458		NA	NA	NA
hsa-miR-26a-5p	TNFRSF10D	-0.352368463397074	0.362040749917446	-1.21291781589212	0.12813188438224	mirMAP	-0.443727421653665	0.000175681471900891		NA	NA	NA
hsa-miR-766-3p	TNFRSF1A	2.6460519504539	8.60200045402435e-06	-0.659377512671059	0.0889418349306143	MirTarget	-0.100128221820332	0.00599976091689645		NA	NA	NA
hsa-miR-129-5p	TNFSF10	-2.66843722411409	0.00695783358331245	2.118758562145	0.0216437100588859	miRanda	-0.207618069660698	9.59656903576055e-05		NA	NA	NA
hsa-miR-217	TNFSF10	-0.378397407994341	0.717408682071252	2.118758562145	0.0216437100588859	miRanda	-0.202017009365184	5.47278192731572e-05		NA	NA	NA
hsa-miR-361-5p	TNFSF10	0.00649167180664723	0.985202350239079	2.118758562145	0.0216437100588859	miRanda	-0.417422213365056	0.00645858491593377		NA	NA	NA
hsa-miR-324-3p	TRADD	1.51345381556672	0.0038447546677657	1.087891208472	0.00809576832135138	miRNATAP	-0.163418626847223	0.000228267741497048		NA	NA	NA
hsa-miR-17-5p	XIAP	2.3269271449522	2.13987445663942e-05	0.21193990907902	0.492489660258725	miRNAWalker2_validate;TargetScan	-0.115272263388315	0.000232899306031091		NA	NA	NA
hsa-miR-19b-1-5p	XIAP	1.51335451095424	0.0014717605268143	0.21193990907902	0.492489660258725	MirTarget	-0.130591301091723	0.000335776643741966		NA	NA	NA
hsa-miR-19b-3p	XIAP	1.67581705793313	0.000858910586302716	0.21193990907902	0.492489660258725	mirMAP	-0.100699249525642	0.00352329780167423		NA	NA	NA
hsa-miR-25-3p	XIAP	1.12623030168869	0.00311079344417173	0.21193990907902	0.492489660258725	mirMAP	-0.166772933993496	0.000279588647819815		NA	NA	NA
hsa-miR-32-3p	XIAP	2.20477794939766	0.0392771274032852	0.21193990907902	0.492489660258725	mirMAP	-0.100227774344178	0.000439730838218322		NA	NA	NA
hsa-miR-484	XIAP	1.79050445056016	0.000217287101253701	0.21193990907902	0.492489660258725	mirMAP	-0.105802985633609	0.00311442744504824		NA	NA	NA
hsa-miR-92a-3p	XIAP	1.87892405805529	1.27013821556583e-05	0.21193990907902	0.492489660258725	mirMAP	-0.136415865455041	0.000676507864354257		NA	NA	NA