miRNA	gene	miRNA_log2FC	miRNA_pvalue	gene_log2FC	gene_pvalue	interactions	correlation_beta	correlation_pvalue	PMID	evidence	outcome	cancer	OLS.miRNA_effect_size	OLS.covariates_effect_size
hsa-miR-107	WIF1	0.351433472692356	0.523819413335979	2.05165480467634	2.76919327749875e-05	miRanda	-0.805243011250718	6.66023850485786e-06		NA	NA	NA	-0.81	type:-3.39,stage:-0.37,histology:-0.15,PAM50:-0.45,ER:0.11,PR:0.07,HER2:-0.17,Triple_Negative:1.68
hsa-miR-484	SFRP1	0.411127332258218	0.453891011654088	3.81079089449119	6.71783240746346e-08	MirTarget	-0.736652971526416	5.14194951874832e-12		NA	NA	NA	-0.79	type:-5.75,stage:-0.19,histology:-0.12,PAM50:-1.1,ER:0.39,PR:-0.38,HER2:-1.15,Triple_Negative:1.64
hsa-miR-1301-3p	SFRP1	1.13236779080729	0.00035660210335027	3.81079089449119	6.71783240746346e-08	MirTarget	-0.627568666111828	8.02299635565225e-16		NA	NA	NA	-0.54	type:-5.36,stage:-0.13,histology:-0.13,PAM50:-1.1,ER:0.15,PR:-0.44,HER2:-0.96,Triple_Negative:1.68
hsa-miR-16-5p	WNT5A	0.608716035131087	0.441059798918702	-0.489836165906155	0.238638304352526	miRNAWalker2_validate	-0.443371863255678	2.01154967356747e-14		NA	NA	NA	-0.48	type:2.47,stage:-0.21,histology:-0.1,PAM50:-0.03,ER:-0.02,PR:0.72,HER2:0.36,Triple_Negative:0.35
hsa-miR-107	FZD10	0.351433472692356	0.523819413335979	-0.299243475585232	0.163139309328814	miRanda	-0.400790225805032	2.23315200602984e-08		NA	NA	NA	-0.45	type:0.61,stage:-0.18,histology:0.07,PAM50:-0.05,ER:0.42,PR:-0.11,HER2:-0.2,Triple_Negative:0.04
hsa-miR-590-3p	WIF1	1.01238246880436	6.25794947126089e-07	2.05165480467634	2.76919327749875e-05	PITA;miRanda;mirMAP	-0.639334008119333	9.64663705878253e-08		NA	NA	NA	-0.44	type:-3.84,stage:-0.32,histology:-0.14,PAM50:-0.54,ER:-0.07,PR:0.06,HER2:-0.11,Triple_Negative:1.5
hsa-miR-24-3p	CAMK2B	0.834102408142648	0.36961872772158	-1.555594885724	1.35370226826514e-06	MirTarget	-0.668590574540919	9.25330039258928e-14		NA	NA	NA	-0.42	type:3.05,stage:0.05,histology:0.05,PAM50:0.45,ER:0.64,PR:0.38,HER2:-0.14,Triple_Negative:0.63
hsa-miR-30e-5p	WNT5A	0.74013844669909	0.511970582859704	-0.489836165906155	0.238638304352526	mirMAP	-0.355937424695316	3.98104999357833e-07		NA	NA	NA	-0.41	type:2.04,stage:-0.22,histology:-0.12,PAM50:-0.11,ER:0.07,PR:0.74,HER2:0.34,Triple_Negative:0.28
hsa-miR-17-3p	FZD4	1.46616632235897	0.0418591337484843	-0.757353288322241	0.186174262226182	MirTarget	-0.488528178794328	1.80113152001825e-35		NA	NA	NA	-0.37	type:-3.88,stage:-0.05,histology:-0.03,PAM50:-0.05,ER:-0.26,PR:-0.11,HER2:0.08,Triple_Negative:-0.65
hsa-miR-200c-3p	FZD4	0.368794286773724	0.756435233803377	-0.757353288322241	0.186174262226182	mirMAP	-0.5394698778619	2.40222703670541e-71		NA	NA	NA	-0.37	type:-3.68,stage:-0.04,histology:-0.01,PAM50:0.03,ER:-0.31,PR:-0.11,HER2:0.07,Triple_Negative:-0.95
hsa-miR-92a-3p	WNT5A	1.22719477478376	0.303128344063904	-0.489836165906155	0.238638304352526	miRNAWalker2_validate	-0.456191278985706	5.11502285589708e-16		NA	NA	NA	-0.37	type:2.07,stage:-0.21,histology:-0.11,PAM50:-0.09,ER:0,PR:0.73,HER2:0.4,Triple_Negative:0.41
hsa-miR-30c-5p	WNT7B	0.2904764284977	0.738803502565399	-0.955718862585083	0.0163160861680099	miRNATAP	-0.455544291260138	2.11209121770824e-09		NA	NA	NA	-0.37	type:0.5,stage:0.09,histology:-0.12,PAM50:0.23,ER:-0.16,PR:-0.38,HER2:0.51,Triple_Negative:-0.87
hsa-miR-96-5p	SFRP1	0.100415780625178	0.816616062681011	3.81079089449119	6.71783240746346e-08	mirMAP	-0.844516363711542	6.21667681893678e-38		NA	NA	NA	-0.36	type:-5.51,stage:-0.13,histology:-0.1,PAM50:-1.1,ER:0.29,PR:-0.23,HER2:-1.11,Triple_Negative:1.38
hsa-miR-589-5p	CXXC4	0.230201267274126	0.668365586561059	-1.30769268523275	5.95588414495972e-07	MirTarget;miRNATAP	-0.397030086932275	6.52239923121845e-07		NA	NA	NA	-0.35	type:-0.45,stage:-0.16,histology:-0.05,PAM50:0.36,ER:0.35,PR:-0.67,HER2:0.29,Triple_Negative:-0.74
hsa-miR-16-1-3p	SFRP1	0.416431607020454	0.0443663162632403	3.81079089449119	6.71783240746346e-08	MirTarget	-0.711103027959144	8.81693153322732e-12		NA	NA	NA	-0.35	type:-5.14,stage:-0.13,histology:-0.1,PAM50:-1.13,ER:0.51,PR:-0.19,HER2:-1.02,Triple_Negative:1.71
hsa-miR-362-5p	CAMK2B	0.820801646347614	0.0107637300891325	-1.555594885724	1.35370226826514e-06	miRNATAP	-0.373141196834054	2.76360587755669e-09		NA	NA	NA	-0.34	type:2.37,stage:0.09,histology:0.04,PAM50:0.48,ER:0.51,PR:0.38,HER2:-0.17,Triple_Negative:0.47
hsa-miR-330-5p	WIF1	0.563423954500856	0.194785172695321	2.05165480467634	2.76919327749875e-05	miRanda	-0.660990097984299	2.58056748637709e-06		NA	NA	NA	-0.34	type:-3.56,stage:-0.36,histology:-0.14,PAM50:-0.49,ER:0.1,PR:0.15,HER2:-0.11,Triple_Negative:1.58
hsa-miR-141-3p	FZD4	0.518554136840043	0.543645265590794	-0.757353288322241	0.186174262226182	TargetScan	-0.485144243770508	8.88244662789011e-86		NA	NA	NA	-0.33	type:-3.26,stage:-0.07,histology:-0.01,PAM50:0.04,ER:-0.28,PR:-0.14,HER2:0.08,Triple_Negative:-0.91
hsa-miR-7-1-3p	SFRP1	-0.136535237676745	0.726879891153832	3.81079089449119	6.71783240746346e-08	MirTarget;mirMAP	-0.630150561051086	2.75485010272039e-12		NA	NA	NA	-0.31	type:-6.3,stage:-0.1,histology:-0.11,PAM50:-1.1,ER:0.41,PR:-0.25,HER2:-1.13,Triple_Negative:1.41
hsa-miR-374a-5p	WNT3	0.47302975636239	0.309552532909276	-0.240302124351824	0.215821203926234	MirTarget	-0.450647176110379	8.40472532505734e-11		NA	NA	NA	-0.31	type:2.78,stage:-0.04,histology:0.03,PAM50:0.32,ER:0.64,PR:-0.13,HER2:-0.56,Triple_Negative:0.95
hsa-miR-98-5p	FZD10	0.611305673326084	0.243973203190168	-0.299243475585232	0.163139309328814	miRNAWalker2_validate	-0.461667265087064	4.29163451584181e-11		NA	NA	NA	-0.3	type:0.29,stage:-0.15,histology:0.06,PAM50:-0.11,ER:0.43,PR:-0.08,HER2:-0.2,Triple_Negative:-0.03
hsa-miR-200b-3p	FZD4	0.224286846990266	0.786394257540977	-0.757353288322241	0.186174262226182	mirMAP	-0.443472478111004	1.62241648876776e-56		NA	NA	NA	-0.3	type:-3.23,stage:-0.08,histology:-0.02,PAM50:0.01,ER:0.06,PR:-0.15,HER2:0.02,Triple_Negative:-0.78
hsa-miR-30d-5p	CAMK2A	0.171445446354708	0.882863964947721	-0.121211311432653	0.634125054925633	mirMAP	-0.500830199163001	3.66036488570952e-13		NA	NA	NA	-0.29	type:1.39,stage:-0.09,histology:-0.14,PAM50:-0.14,ER:0.42,PR:-0.05,HER2:0.52,Triple_Negative:0
hsa-miR-141-5p	DAAM2	0.148357564860886	0.854593186542924	-0.0402745144958083	0.924877679800936	mirMAP	-0.38681514285257	1.29341814943135e-41		NA	NA	NA	-0.29	type:-0.82,stage:0,histology:0.11,PAM50:-0.11,ER:0.4,PR:-0.19,HER2:-0.11,Triple_Negative:-0.02
hsa-miR-330-5p	FZD4	0.563423954500856	0.194785172695321	-0.757353288322241	0.186174262226182	miRanda;miRNATAP	-0.413410414565267	1.56474033349077e-20		NA	NA	NA	-0.28	type:-3.62,stage:-0.05,histology:-0.03,PAM50:0.01,ER:-0.2,PR:-0.04,HER2:0.17,Triple_Negative:-0.78
hsa-miR-29c-3p	PRKX	-0.643278710106618	0.522845109493165	1.91740115243831	2.73254159111166e-05	mirMAP	-0.38827959473025	7.47361121556913e-23		NA	NA	NA	-0.28	type:-0.81,stage:-0.07,histology:-0.09,PAM50:-0.28,ER:-0.22,PR:-0.2,HER2:-0.22,Triple_Negative:0.74
hsa-miR-93-5p	CCND2	0.943892623097563	0.3984984603332	-0.0682487762990531	0.88928033898544	miRNATAP	-0.400435186075896	5.37578279205249e-31		NA	NA	NA	-0.27	type:-1.71,stage:-0.02,histology:-0.1,PAM50:-0.08,ER:-0.12,PR:0.12,HER2:-0.02,Triple_Negative:-0.02
hsa-miR-660-5p	CXXC4	0.789334042528136	0.108629249007974	-1.30769268523275	5.95588414495972e-07	miRNATAP	-0.558306258370776	2.42822704122193e-19		NA	NA	NA	-0.27	type:-0.88,stage:-0.14,histology:-0.07,PAM50:0.32,ER:0.43,PR:-0.69,HER2:0.13,Triple_Negative:-0.68
hsa-miR-361-5p	PRICKLE2	0.295581181703002	0.679805903809273	-1.20320410751354	0.0117589308024567	MirTarget;PITA;miRanda;miRNATAP	-0.423190675531575	1.14669419541242e-08		NA	NA	NA	-0.27	type:-1.45,stage:-0.06,histology:-0.03,PAM50:0.06,ER:0.28,PR:0.18,HER2:0.17,Triple_Negative:-0.61
hsa-miR-29b-2-5p	PRKCA	-1.15291700929952	0.0234666802434694	1.08545977988408	0.000986469275480055	mirMAP	-0.365220324605892	6.60788568306249e-22		NA	NA	NA	-0.27	type:-2.76,stage:-0.04,histology:-0.05,PAM50:-0.2,ER:-0.02,PR:-0.23,HER2:-0.2,Triple_Negative:0.06
hsa-miR-141-3p	SOX17	0.518554136840043	0.543645265590794	-0.560525779482175	0.0308240186992835	TargetScan	-0.426856956954328	5.06746881736312e-61	22921431	Inhibition of SOX17 by microRNA 141 and methylation activates the WNT signaling pathway in esophageal cancer; MicroRNA 141 was also found to down-regulate SOX17 expression and activate the WNT signal pathway		esophageal cancer	-0.27	type:-1.81,stage:-0.08,histology:0.04,PAM50:0.02,ER:0.02,PR:-0.01,HER2:-0.05,Triple_Negative:-0.32
hsa-miR-532-5p	CXXC4	0.837154623550648	0.324129802476266	-1.30769268523275	5.95588414495972e-07	MirTarget;PITA;miRNATAP	-0.496712025500665	4.77750045893798e-12		NA	NA	NA	-0.26	type:-0.91,stage:-0.15,histology:-0.07,PAM50:0.33,ER:0.4,PR:-0.7,HER2:0.15,Triple_Negative:-0.69
hsa-miR-182-5p	SFRP1	-0.350218686073308	0.794131834526037	3.81079089449119	6.71783240746346e-08	mirMAP	-0.967266087949178	4.26592739938163e-34		NA	NA	NA	-0.26	type:-5.71,stage:-0.14,histology:-0.11,PAM50:-1.11,ER:0.42,PR:-0.17,HER2:-1.08,Triple_Negative:1.42
hsa-miR-2355-5p	CAMK2B	0.516125245105019	0.301078573145612	-1.555594885724	1.35370226826514e-06	mirMAP	-0.534987844428681	2.11741953815093e-09		NA	NA	NA	-0.25	type:2.82,stage:0.06,histology:0.06,PAM50:0.48,ER:0.63,PR:0.36,HER2:-0.11,Triple_Negative:0.44
hsa-miR-342-3p	FOSL1	-0.720941204737844	0.328091715069398	2.26372050140397	1.10214789227674e-19	miRanda	-0.403573240229472	2.83490772906014e-18		NA	NA	NA	-0.25	type:-0.72,stage:-0.06,histology:-0.05,PAM50:-0.31,ER:-0.41,PR:-0.07,HER2:-0.34,Triple_Negative:0.94
hsa-miR-429	FZD4	0.448029985835258	0.437184735816941	-0.757353288322241	0.186174262226182	mirMAP	-0.419642690763874	1.62254290929758e-64		NA	NA	NA	-0.25	type:-3.21,stage:-0.07,histology:-0.02,PAM50:0,ER:0.02,PR:-0.17,HER2:0.06,Triple_Negative:-0.8
hsa-miR-26a-5p	VANGL1	-0.0526989605494563	0.958167127738582	0.090913351384871	0.851935336497162	mirMAP	-0.376690599739968	1.73365456652659e-24		NA	NA	NA	-0.25	type:1.19,stage:0.01,histology:0.01,PAM50:0.04,ER:-0.26,PR:0.09,HER2:0.17,Triple_Negative:0.03
hsa-miR-182-5p	DAAM2	-0.350218686073308	0.794131834526037	-0.0402745144958083	0.924877679800936	mirMAP	-0.428502281083267	1.77522555258754e-41		NA	NA	NA	-0.24	type:-1.67,stage:0.02,histology:0.1,PAM50:-0.15,ER:0.32,PR:-0.11,HER2:-0.17,Triple_Negative:-0.26
hsa-miR-374a-5p	CCND1	0.47302975636239	0.309552532909276	-1.63598241592522	0.0353580902191039	MirTarget	-0.556352001430099	7.67413515717595e-16	27191497	microRNA 374a suppresses colon cancer progression by directly reducing CCND1 to inactivate the PI3K/AKT pathway; Furthermore luciferase reporter assays confirmed that miR-374a could directly reduce CCND1; We examined miR-374a levels by in situ hybridization and its correlation with CCND1 expression in CRC tumor tissues; High miR-374a expression with low level of CCND1 was protective factor in CRC; Together these findings indicate that miR-374a inactivates the PI3K/AKT axis by inhibiting CCND1 suppressing of colon cancer progression	progression	colon cancer	-0.23	type:2.74,stage:0.02,histology:0.03,PAM50:0.27,ER:1.01,PR:-0.19,HER2:0.22,Triple_Negative:-0.07
hsa-miR-664a-3p	WNT10A	-0.254427346780448	0.599878061586463	2.09356067552938	1.34132402888639e-18	mirMAP	-0.421214281367344	2.22889192706043e-09		NA	NA	NA	-0.23	type:-1.33,stage:0.07,histology:-0.16,PAM50:-0.41,ER:-0.25,PR:0.09,HER2:-0.37,Triple_Negative:0.87
hsa-miR-3127-5p	FZD4	0.14676111885184	0.566846453082815	-0.757353288322241	0.186174262226182	MirTarget	-0.353612933288253	8.25127810305334e-22		NA	NA	NA	-0.22	type:-4.2,stage:-0.04,histology:-0.03,PAM50:0.04,ER:-0.24,PR:-0.14,HER2:0.15,Triple_Negative:-0.98
hsa-miR-30d-5p	WNT5A	0.171445446354708	0.882863964947721	-0.489836165906155	0.238638304352526	mirMAP	-0.395918928140374	3.76530346593888e-09		NA	NA	NA	-0.22	type:1.88,stage:-0.21,histology:-0.12,PAM50:-0.05,ER:0.1,PR:0.76,HER2:0.37,Triple_Negative:0.19
hsa-miR-17-5p	FZD4	1.80801649919324	0.017740816345401	-0.757353288322241	0.186174262226182	TargetScan	-0.379930791437764	1.81308518580408e-28		NA	NA	NA	-0.21	type:-4.29,stage:-0.04,histology:-0.03,PAM50:-0.03,ER:-0.33,PR:-0.09,HER2:0.09,Triple_Negative:-0.83
hsa-miR-21-5p	FZD4	-0.142759573450327	0.928848736959803	-0.757353288322241	0.186174262226182	mirMAP	-0.617423104849022	4.14640575991911e-50		NA	NA	NA	-0.21	type:-3.77,stage:-0.05,histology:-0.03,PAM50:-0.01,ER:-0.16,PR:-0.04,HER2:0.2,Triple_Negative:-1
hsa-let-7i-5p	NLK	0.491983487993952	0.539800598932235	-0.495551021243264	0.250356691034228	miRNATAP	-0.413862391863088	2.49706725878225e-22		NA	NA	NA	-0.21	type:1.13,stage:0.01,histology:0,PAM50:0.13,ER:-0.06,PR:0.02,HER2:0.3,Triple_Negative:-0.11
hsa-miR-183-5p	PRKCA	0.204550384370393	0.863354421890003	1.08545977988408	0.000986469275480055	miRNATAP	-0.382401275003301	4.39521361355191e-39		NA	NA	NA	-0.21	type:-2.18,stage:-0.04,histology:-0.06,PAM50:-0.29,ER:-0.09,PR:-0.25,HER2:-0.12,Triple_Negative:0.17
hsa-miR-106b-5p	FZD4	1.04856358809711	0.139094273282727	-0.757353288322241	0.186174262226182	miRNATAP	-0.578879980215605	3.05048677233544e-41		NA	NA	NA	-0.2	type:-4.18,stage:-0.05,histology:-0.03,PAM50:-0.01,ER:-0.26,PR:-0.08,HER2:0.09,Triple_Negative:-0.9
hsa-miR-590-3p	PRICKLE2	1.01238246880436	6.25794947126089e-07	-1.20320410751354	0.0117589308024567	MirTarget;PITA;miRanda;mirMAP;miRNATAP	-0.428246782039215	4.12749671901844e-37		NA	NA	NA	-0.2	type:-1.18,stage:-0.07,histology:-0.02,PAM50:0.05,ER:0.14,PR:0.17,HER2:0.23,Triple_Negative:-0.63
hsa-miR-200c-3p	PRKCA	0.368794286773724	0.756435233803377	1.08545977988408	0.000986469275480055	miRNATAP	-0.384868851727468	4.79014422420278e-32		NA	NA	NA	-0.2	type:-2.33,stage:-0.03,histology:-0.06,PAM50:-0.28,ER:-0.07,PR:-0.24,HER2:-0.17,Triple_Negative:0.23
hsa-miR-625-5p	SFRP1	-0.12821717169837	0.460013404839361	3.81079089449119	6.71783240746346e-08	MirTarget	-0.628996046116407	2.3830320131247e-12		NA	NA	NA	-0.2	type:-5.05,stage:-0.1,histology:-0.11,PAM50:-1.1,ER:0.61,PR:-0.14,HER2:-0.94,Triple_Negative:1.75
hsa-miR-148b-3p	TCF7L2	0.139560003671114	0.825716083905455	0.811247817411131	0.0903116083585558	miRNAWalker2_validate	-0.36003166883339	8.1210275031183e-21		NA	NA	NA	-0.2	type:-1.45,stage:-0.06,histology:-0.05,PAM50:-0.28,ER:0.04,PR:-0.03,HER2:-0.02,Triple_Negative:0.23
hsa-miR-186-5p	CCND1	1.04333228080691	0.148711371364268	-1.63598241592522	0.0353580902191039	mirMAP	-0.494988902443749	5.18517439622754e-18		NA	NA	NA	-0.19	type:2.53,stage:0.02,histology:0.04,PAM50:0.26,ER:0.88,PR:-0.16,HER2:0.16,Triple_Negative:-0.1
hsa-miR-374b-5p	CCND1	0.478896841162915	0.365769179152496	-1.63598241592522	0.0353580902191039	miRNAWalker2_validate;MirTarget	-0.531193112029599	5.3445494840887e-15		NA	NA	NA	-0.19	type:2.66,stage:0.02,histology:0.03,PAM50:0.27,ER:1,PR:-0.17,HER2:0.2,Triple_Negative:-0.1
hsa-let-7a-3p	FZD4	0.311896921808493	0.499509698073189	-0.757353288322241	0.186174262226182	mirMAP	-0.407977804308959	4.19813220404563e-15		NA	NA	NA	-0.19	type:-3.99,stage:-0.05,histology:-0.02,PAM50:0,ER:-0.14,PR:-0.05,HER2:0.1,Triple_Negative:-0.89
hsa-miR-18a-5p	PRICKLE2	2.29585803678176	4.13931899001596e-14	-1.20320410751354	0.0117589308024567	MirTarget	-0.387730469036141	3.85619154280423e-61		NA	NA	NA	-0.19	type:-1.1,stage:-0.06,histology:-0.02,PAM50:0.04,ER:0.13,PR:0.11,HER2:0.24,Triple_Negative:-0.46
hsa-miR-19a-3p	PRICKLE2	1.46790979235261	0.000361171910570302	-1.20320410751354	0.0117589308024567	MirTarget;miRNATAP	-0.402369518872812	5.04349600060003e-48		NA	NA	NA	-0.19	type:-1.25,stage:-0.06,histology:-0.02,PAM50:0.06,ER:0.15,PR:0.13,HER2:0.22,Triple_Negative:-0.57
hsa-miR-19b-3p	PRICKLE2	1.16012277183793	0.0628519598637838	-1.20320410751354	0.0117589308024567	MirTarget;miRNATAP	-0.400025342580155	8.2019109465105e-31		NA	NA	NA	-0.19	type:-1.31,stage:-0.07,histology:-0.01,PAM50:0.06,ER:0.17,PR:0.18,HER2:0.18,Triple_Negative:-0.57
hsa-miR-590-5p	PRICKLE2	1.40236682288609	3.89322108176281e-06	-1.20320410751354	0.0117589308024567	MirTarget;PITA;miRanda	-0.400059229125334	2.18643891880232e-35		NA	NA	NA	-0.19	type:-1.55,stage:-0.06,histology:-0.02,PAM50:0.05,ER:0.05,PR:0.15,HER2:0.19,Triple_Negative:-0.68
hsa-miR-15a-5p	CCND2	0.342480184869245	0.605040217513538	-0.0682487762990531	0.88928033898544	miRNAWalker2_validate;miRTarBase;miRNATAP	-0.382989347535057	1.85935181542133e-19		NA	NA	NA	-0.18	type:-1.47,stage:-0.04,histology:-0.09,PAM50:-0.06,ER:-0.01,PR:0.18,HER2:0,Triple_Negative:-0.01
hsa-miR-192-5p	FZD4	0.471716293688646	0.531156230462861	-0.757353288322241	0.186174262226182	miRNAWalker2_validate;mirMAP	-0.417317983267879	3.23659392050309e-28		NA	NA	NA	-0.18	type:-4.21,stage:-0.05,histology:-0.02,PAM50:0,ER:-0.25,PR:-0.09,HER2:0.12,Triple_Negative:-1
hsa-miR-93-5p	PLCB1	0.943892623097563	0.3984984603332	-0.0673741770895395	0.858739825346359	miRNATAP	-0.375873317446529	2.70002798262841e-11		NA	NA	NA	-0.18	type:-3.61,stage:0.12,histology:-0.04,PAM50:-0.17,ER:-0.46,PR:-0.04,HER2:0.18,Triple_Negative:-0.68
hsa-miR-330-5p	SOX17	0.563423954500856	0.194785172695321	-0.560525779482175	0.0308240186992835	miRanda	-0.461434964169255	9.94438298481541e-25		NA	NA	NA	-0.18	type:-2.24,stage:-0.06,histology:0.02,PAM50:-0.01,ER:0.09,PR:0.08,HER2:0.01,Triple_Negative:-0.26
hsa-miR-429	MAPK10	0.448029985835258	0.437184735816941	-0.143859111717503	0.649958288293509	miRNATAP	-0.366481358214565	1.02092652001284e-20		NA	NA	NA	-0.17	type:-0.26,stage:-0.3,histology:-0.11,PAM50:-0.01,ER:0.31,PR:0,HER2:0.38,Triple_Negative:0.29
hsa-miR-185-5p	NFATC2	0.413180953895098	0.435464963453554	-0.403723192975259	0.136549575851534	MirTarget	-0.480154397877674	9.64194904728437e-08		NA	NA	NA	-0.17	type:-2.44,stage:-0.02,histology:-0.07,PAM50:-0.09,ER:0.25,PR:0.11,HER2:-0.35,Triple_Negative:-0.34
hsa-miR-107	PLCB1	0.351433472692356	0.523819413335979	-0.0673741770895395	0.858739825346359	PITA;miRanda;miRNATAP	-0.43540927048432	3.17440164078589e-09		NA	NA	NA	-0.16	type:-3.37,stage:0.1,histology:-0.04,PAM50:-0.14,ER:-0.38,PR:-0.02,HER2:0.2,Triple_Negative:-0.64
hsa-miR-98-5p	FZD4	0.611305673326084	0.243973203190168	-0.757353288322241	0.186174262226182	MirTarget	-0.528062971038367	1.52945921080448e-21		NA	NA	NA	-0.15	type:-4.23,stage:-0.03,histology:-0.03,PAM50:-0.02,ER:-0.19,PR:-0.03,HER2:0.11,Triple_Negative:-0.93
hsa-miR-148b-3p	PRICKLE2	0.139560003671114	0.825716083905455	-1.20320410751354	0.0117589308024567	MirTarget;miRNATAP	-0.368462111806635	1.62423559573341e-16		NA	NA	NA	-0.15	type:-1.19,stage:-0.08,histology:-0.01,PAM50:0.09,ER:0.2,PR:0.17,HER2:0.22,Triple_Negative:-0.69
hsa-miR-15b-3p	PRICKLE2	1.33683404747498	0.00122709276757981	-1.20320410751354	0.0117589308024567	mirMAP	-0.350402182346711	3.40989651980756e-35		NA	NA	NA	-0.15	type:-1.02,stage:-0.07,histology:-0.02,PAM50:0.08,ER:0.18,PR:0.16,HER2:0.23,Triple_Negative:-0.55
hsa-miR-130b-3p	FZD4	1.16970507422762	6.85086072809354e-05	-0.757353288322241	0.186174262226182	mirMAP	-0.413297584170443	1.17616241857261e-31		NA	NA	NA	-0.14	type:-4.01,stage:-0.05,histology:-0.03,PAM50:0,ER:-0.26,PR:-0.06,HER2:0.15,Triple_Negative:-0.89
hsa-miR-590-3p	FZD4	1.01238246880436	6.25794947126089e-07	-0.757353288322241	0.186174262226182	miRanda;mirMAP;miRNATAP	-0.406671608133116	3.85657572987706e-27		NA	NA	NA	-0.14	type:-4.19,stage:-0.05,histology:-0.03,PAM50:-0.02,ER:-0.25,PR:-0.05,HER2:0.12,Triple_Negative:-0.95
hsa-miR-106b-5p	PLCB1	1.04856358809711	0.139094273282727	-0.0673741770895395	0.858739825346359	miRNATAP	-0.353580999854292	7.45108046911457e-10		NA	NA	NA	-0.14	type:-3.44,stage:0.1,histology:-0.04,PAM50:-0.16,ER:-0.42,PR:-0.04,HER2:0.18,Triple_Negative:-0.65
hsa-miR-361-5p	MAPK8	0.295581181703002	0.679805903809273	0.135890279695962	0.686366474054282	PITA;miRanda;mirMAP	-0.36263548128247	3.21553639920568e-09		NA	NA	NA	-0.13	type:-0.52,stage:-0.02,histology:-0.01,PAM50:0,ER:0.04,PR:-0.19,HER2:-0.17,Triple_Negative:-0.01
hsa-miR-429	SFRP1	0.448029985835258	0.437184735816941	3.81079089449119	6.71783240746346e-08	miRNATAP	-0.482539995817486	1.02848505471575e-13		NA	NA	NA	-0.13	type:-5.59,stage:-0.14,histology:-0.12,PAM50:-1.12,ER:0.57,PR:-0.24,HER2:-1.09,Triple_Negative:1.63
hsa-let-7d-5p	FZD4	0.737311896446371	0.277996131668254	-0.757353288322241	0.186174262226182	MirTarget;miRNATAP	-0.378548770288792	7.31572406282056e-13		NA	NA	NA	-0.11	type:-4.26,stage:-0.05,histology:-0.03,PAM50:-0.02,ER:-0.2,PR:-0.03,HER2:0.1,Triple_Negative:-0.94
hsa-miR-32-5p	FZD4	0.531860098119996	0.195500436097555	-0.757353288322241	0.186174262226182	mirMAP	-0.393954741435993	7.79828021744844e-23		NA	NA	NA	-0.1	type:-4.17,stage:-0.05,histology:-0.02,PAM50:0,ER:-0.22,PR:-0.04,HER2:0.11,Triple_Negative:-0.96
hsa-miR-590-5p	SOX17	1.40236682288609	3.89322108176281e-06	-0.560525779482175	0.0308240186992835	miRanda	-0.386693548488825	4.68900931678905e-26		NA	NA	NA	-0.1	type:-2.84,stage:-0.05,histology:0.02,PAM50:-0.03,ER:-0.02,PR:0.06,HER2:-0.04,Triple_Negative:-0.39
hsa-miR-429	WIF1	0.448029985835258	0.437184735816941	2.05165480467634	2.76919327749875e-05	miRanda	-0.57801116079909	1.92906319858818e-12		NA	NA	NA	-0.1	type:-4.24,stage:-0.35,histology:-0.13,PAM50:-0.56,ER:0.23,PR:0.15,HER2:-0.23,Triple_Negative:1.36
hsa-miR-361-5p	PPP2R5E	0.295581181703002	0.679805903809273	-0.11093062617899	0.808255495902328	miRanda	-0.362844376404808	1.47810752731031e-18		NA	NA	NA	-0.09	type:0.13,stage:0.04,histology:0.01,PAM50:0,ER:-0.14,PR:0,HER2:0.19,Triple_Negative:-0.18
hsa-miR-589-5p	PRICKLE2	0.230201267274126	0.668365586561059	-1.20320410751354	0.0117589308024567	MirTarget;miRNATAP	-0.410788762794066	5.39765560115147e-16		NA	NA	NA	-0.09	type:-1.33,stage:-0.07,histology:-0.01,PAM50:0.07,ER:0.19,PR:0.21,HER2:0.25,Triple_Negative:-0.69
hsa-miR-340-5p	ROCK2	0.362079103949629	0.350652374274417	0.377201812755962	0.433848507428904	mirMAP	-0.395127263389571	3.35868529258436e-20		NA	NA	NA	-0.09	type:-2.16,stage:0,histology:0,PAM50:-0.09,ER:-0.14,PR:-0.31,HER2:-0.06,Triple_Negative:-0.23
hsa-miR-590-3p	SOX17	1.01238246880436	6.25794947126089e-07	-0.560525779482175	0.0308240186992835	miRanda;miRNATAP	-0.437832269833539	1.45583399447421e-30		NA	NA	NA	-0.09	type:-2.62,stage:-0.05,histology:0.02,PAM50:-0.02,ER:0.05,PR:0.07,HER2:-0.02,Triple_Negative:-0.37
hsa-let-7i-5p	CCND1	0.491983487993952	0.539800598932235	-1.63598241592522	0.0353580902191039	miRNATAP	-0.759700962013673	2.31065071397228e-16		NA	NA	NA	-0.08	type:2.76,stage:0.02,histology:0.04,PAM50:0.27,ER:1,PR:-0.14,HER2:0.19,Triple_Negative:-0.12
hsa-miR-92a-3p	CCND1	1.22719477478376	0.303128344063904	-1.63598241592522	0.0353580902191039	miRNAWalker2_validate	-0.355039027931141	1.3665845638516e-10		NA	NA	NA	-0.08	type:2.79,stage:0.02,histology:0.05,PAM50:0.27,ER:0.98,PR:-0.15,HER2:0.18,Triple_Negative:-0.08
hsa-miR-146b-5p	CXXC4	0.876334790841257	0.284935762703604	-1.30769268523275	5.95588414495972e-07	MirTarget;miRNATAP	-0.402161602310286	2.78295064213365e-12		NA	NA	NA	-0.08	type:-0.44,stage:-0.15,histology:-0.06,PAM50:0.36,ER:0.52,PR:-0.66,HER2:0.18,Triple_Negative:-0.65
hsa-miR-107	FZD4	0.351433472692356	0.523819413335979	-0.757353288322241	0.186174262226182	miRNATAP	-0.462830534136136	4.14785600961069e-16		NA	NA	NA	-0.06	type:-4.3,stage:-0.05,histology:-0.02,PAM50:-0.01,ER:-0.2,PR:-0.02,HER2:0.11,Triple_Negative:-0.97
hsa-miR-340-5p	NFATC2	0.362079103949629	0.350652374274417	-0.403723192975259	0.136549575851534	miRNATAP	-0.377355443179726	1.70562760392822e-08		NA	NA	NA	-0.06	type:-1.88,stage:-0.03,histology:-0.06,PAM50:-0.07,ER:0.44,PR:0.06,HER2:-0.32,Triple_Negative:-0.21
hsa-miR-590-3p	AXIN2	1.01238246880436	6.25794947126089e-07	-1.12620971420341	0.00118293795582942	MirTarget;PITA;miRanda;miRNATAP	-0.363534362507334	4.95187752463635e-26		NA	NA	NA	-0.04	type:1.11,stage:-0.07,histology:0.02,PAM50:0.27,ER:0.52,PR:0.26,HER2:-0.03,Triple_Negative:0.15
hsa-miR-342-3p	WIF1	-0.720941204737844	0.328091715069398	2.05165480467634	2.76919327749875e-05	miRanda	-0.900150959597263	1.15455195350394e-17		NA	NA	NA	-0.04	type:-4.35,stage:-0.35,histology:-0.13,PAM50:-0.51,ER:0.11,PR:0.19,HER2:-0.19,Triple_Negative:1.33
hsa-miR-29a-3p	CCND1	0.46338784979134	0.683743087347155	-1.63598241592522	0.0353580902191039	mirMAP	-0.358623457755512	1.12263469726765e-09		NA	NA	NA	-0.03	type:2.74,stage:0.02,histology:0.04,PAM50:0.27,ER:0.99,PR:-0.13,HER2:0.18,Triple_Negative:-0.13
hsa-miR-532-5p	NFATC4	0.837154623550648	0.324129802476266	-1.30726255124792	0.0139339204728638	mirMAP	-0.351153097111496	2.13922805026231e-12		NA	NA	NA	0	type:0.52,stage:-0.06,histology:-0.02,PAM50:0.29,ER:0.71,PR:-0.23,HER2:-0.13,Triple_Negative:-0.32
hsa-miR-15a-5p	FZD4	0.342480184869245	0.605040217513538	-0.757353288322241	0.186174262226182	MirTarget	-0.396430785367124	8.19331587254851e-14		NA	NA	NA	0.03	type:-4.41,stage:-0.04,histology:-0.02,PAM50:-0.01,ER:-0.2,PR:-0.01,HER2:0.11,Triple_Negative:-1.01
hsa-miR-186-5p	CAMK2B	1.04333228080691	0.148711371364268	-1.555594885724	1.35370226826514e-06	miRNAWalker2_validate;miRNATAP	-0.420009924398004	3.08262880687716e-06		NA	NA	NA	0.09	type:3.24,stage:0.05,histology:0.07,PAM50:0.5,ER:0.75,PR:0.47,HER2:-0.15,Triple_Negative:0.46