miRNA gene miRNA_log2FC miRNA_pvalue gene_log2FC gene_pvalue interactions correlation_beta correlation_pvalue PMID evidence outcome cancer hsa-miR-30a-3p DTL -2.08290159592947 3.95783261640728e-14 2.88324110943737 9.17658044660609e-26 MirTarget -0.177209233369248 0.000367348210606577 22287560 MiR 30a 5p suppresses tumor growth in colon carcinoma by targeting DTL colon cancer hsa-miR-30a-5p DTL -0.878357906436456 0.000509952992366057 2.88324110943737 9.17658044660609e-26 miRNAWalker2_validate;miRTarBase -0.149424981520462 0.0075412664610539 22287560 MiR 30a 5p suppresses tumor growth in colon carcinoma by targeting DTL; Subsequent reporter gene assays confirmed the predicted miR-30a-5p binding site in the 3'untranslated region of DTL; In conclusion our data identified miR-30a-5p as a tumor-suppressing miRNA in colon cancer cells exerting its function via modulation of DTL expression which is frequently overexpressed in colorectal cancer colon cancer hsa-miR-30e-3p DTL -0.215663037684509 0.235375122783546 2.88324110943737 9.17658044660609e-26 MirTarget -0.173779771585741 0.0279567116303741 NA NA NA hsa-miR-664a-3p DTL 0.634721925861133 0.00520070178640421 2.88324110943737 9.17658044660609e-26 mirMAP -0.226841586939843 0.000271076490501865 NA NA NA