TISIDB

Summary
Symbol	AKAP6
Name	A kinase (PRKA) anchor protein 6
Aliases	KIAA0311; mAKAP; AKAP100; PRKA6; ADAP6; protein kinase A anchoring protein 6; ADAP100; A-kinase anchor prote ......
Chromosomal Location	14q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content	Basic function annotation. > Subcellular Location, Domain and Function > Gene Ontology > KEGG and Reactome Pathway

> Subcellular Location, Domain and Function [ TOP ]
Subcellular Location	Sarcoplasmic reticulum. Nucleus membrane. Note=In heart muscle. Participation of multiple targeting signals allow correct intracellular targeting. These may be repeated motifs rich in basic and hydrophobic amino acids, palmitoylated/myristoylated motifs or alternatively splice targeting sequences.
Domain	-
Function	Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes.

> Gene Ontology [ TOP ]
Biological Process	GO:0001508 action potential GO:0001558 regulation of cell growth GO:0003012 muscle system process GO:0003298 physiological muscle hypertrophy GO:0003300 cardiac muscle hypertrophy GO:0003301 physiological cardiac muscle hypertrophy GO:0006140 regulation of nucleotide metabolic process GO:0006164 purine nucleotide biosynthetic process GO:0006171 cAMP biosynthetic process GO:0006470 protein dephosphorylation GO:0006606 protein import into nucleus GO:0006813 potassium ion transport GO:0006816 calcium ion transport GO:0006874 cellular calcium ion homeostasis GO:0006875 cellular metal ion homeostasis GO:0006913 nucleocytoplasmic transport GO:0007204 positive regulation of cytosolic calcium ion concentration GO:0007507 heart development GO:0007517 muscle organ development GO:0009150 purine ribonucleotide metabolic process GO:0009152 purine ribonucleotide biosynthetic process GO:0009165 nucleotide biosynthetic process GO:0009187 cyclic nucleotide metabolic process GO:0009190 cyclic nucleotide biosynthetic process GO:0009260 ribonucleotide biosynthetic process GO:0010469 regulation of receptor activity GO:0010522 regulation of calcium ion transport into cytosol GO:0010524 positive regulation of calcium ion transport into cytosol GO:0010611 regulation of cardiac muscle hypertrophy GO:0010613 positive regulation of cardiac muscle hypertrophy GO:0010720 positive regulation of cell development GO:0010737 protein kinase A signaling GO:0010738 regulation of protein kinase A signaling GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010921 regulation of phosphatase activity GO:0010922 positive regulation of phosphatase activity GO:0010959 regulation of metal ion transport GO:0014074 response to purine-containing compound GO:0014706 striated muscle tissue development GO:0014742 positive regulation of muscle hypertrophy GO:0014743 regulation of muscle hypertrophy GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014896 muscle hypertrophy GO:0014897 striated muscle hypertrophy GO:0015672 monovalent inorganic cation transport GO:0016049 cell growth GO:0016202 regulation of striated muscle tissue development GO:0016311 dephosphorylation GO:0017038 protein import GO:0019722 calcium-mediated signaling GO:0019932 second-messenger-mediated signaling GO:0019933 cAMP-mediated signaling GO:0019935 cyclic-nucleotide-mediated signaling GO:0022898 regulation of transmembrane transporter activity GO:0030307 positive regulation of cell growth GO:0030799 regulation of cyclic nucleotide metabolic process GO:0030800 negative regulation of cyclic nucleotide metabolic process GO:0030802 regulation of cyclic nucleotide biosynthetic process GO:0030803 negative regulation of cyclic nucleotide biosynthetic process GO:0030808 regulation of nucleotide biosynthetic process GO:0030809 negative regulation of nucleotide biosynthetic process GO:0030814 regulation of cAMP metabolic process GO:0030815 negative regulation of cAMP metabolic process GO:0030817 regulation of cAMP biosynthetic process GO:0030818 negative regulation of cAMP biosynthetic process GO:0032386 regulation of intracellular transport GO:0032388 positive regulation of intracellular transport GO:0032409 regulation of transporter activity GO:0032411 positive regulation of transporter activity GO:0032412 regulation of ion transmembrane transporter activity GO:0032414 positive regulation of ion transmembrane transporter activity GO:0032512 regulation of protein phosphatase type 2B activity GO:0032514 positive regulation of protein phosphatase type 2B activity GO:0032516 positive regulation of phosphoprotein phosphatase activity GO:0032844 regulation of homeostatic process GO:0032845 negative regulation of homeostatic process GO:0032846 positive regulation of homeostatic process GO:0033157 regulation of intracellular protein transport GO:0033173 calcineurin-NFAT signaling cascade GO:0034504 protein localization to nucleus GO:0034762 regulation of transmembrane transport GO:0034764 positive regulation of transmembrane transport GO:0034765 regulation of ion transmembrane transport GO:0034767 positive regulation of ion transmembrane transport GO:0035051 cardiocyte differentiation GO:0035265 organ growth GO:0035303 regulation of dephosphorylation GO:0035304 regulation of protein dephosphorylation GO:0035306 positive regulation of dephosphorylation GO:0035307 positive regulation of protein dephosphorylation GO:0042306 regulation of protein import into nucleus GO:0042307 positive regulation of protein import into nucleus GO:0042391 regulation of membrane potential GO:0042692 muscle cell differentiation GO:0042990 regulation of transcription factor import into nucleus GO:0042991 transcription factor import into nucleus GO:0042993 positive regulation of transcription factor import into nucleus GO:0043266 regulation of potassium ion transport GO:0043268 positive regulation of potassium ion transport GO:0043270 positive regulation of ion transport GO:0043500 muscle adaptation GO:0043502 regulation of muscle adaptation GO:0043666 regulation of phosphoprotein phosphatase activity GO:0044057 regulation of system process GO:0044744 protein targeting to nucleus GO:0045844 positive regulation of striated muscle tissue development GO:0045927 positive regulation of growth GO:0045980 negative regulation of nucleotide metabolic process GO:0046058 cAMP metabolic process GO:0046390 ribose phosphate biosynthetic process GO:0046620 regulation of organ growth GO:0046622 positive regulation of organ growth GO:0046683 response to organophosphorus GO:0046822 regulation of nucleocytoplasmic transport GO:0046824 positive regulation of nucleocytoplasmic transport GO:0048016 inositol phosphate-mediated signaling GO:0048588 developmental cell growth GO:0048634 regulation of muscle organ development GO:0048636 positive regulation of muscle organ development GO:0048638 regulation of developmental growth GO:0048639 positive regulation of developmental growth GO:0048738 cardiac muscle tissue development GO:0050848 regulation of calcium-mediated signaling GO:0050850 positive regulation of calcium-mediated signaling GO:0051146 striated muscle cell differentiation GO:0051147 regulation of muscle cell differentiation GO:0051149 positive regulation of muscle cell differentiation GO:0051153 regulation of striated muscle cell differentiation GO:0051155 positive regulation of striated muscle cell differentiation GO:0051169 nuclear transport GO:0051170 nuclear import GO:0051208 sequestering of calcium ion GO:0051209 release of sequestered calcium ion into cytosol GO:0051222 positive regulation of protein transport GO:0051235 maintenance of location GO:0051238 sequestering of metal ion GO:0051279 regulation of release of sequestered calcium ion into cytosol GO:0051281 positive regulation of release of sequestered calcium ion into cytosol GO:0051282 regulation of sequestering of calcium ion GO:0051283 negative regulation of sequestering of calcium ion GO:0051480 regulation of cytosolic calcium ion concentration GO:0051531 NFAT protein import into nucleus GO:0051532 regulation of NFAT protein import into nucleus GO:0051533 positive regulation of NFAT protein import into nucleus GO:0051591 response to cAMP GO:0051924 regulation of calcium ion transport GO:0051928 positive regulation of calcium ion transport GO:0052652 cyclic purine nucleotide metabolic process GO:0055001 muscle cell development GO:0055002 striated muscle cell development GO:0055006 cardiac cell development GO:0055007 cardiac muscle cell differentiation GO:0055013 cardiac muscle cell development GO:0055017 cardiac muscle tissue growth GO:0055021 regulation of cardiac muscle tissue growth GO:0055023 positive regulation of cardiac muscle tissue growth GO:0055024 regulation of cardiac muscle tissue development GO:0055025 positive regulation of cardiac muscle tissue development GO:0055074 calcium ion homeostasis GO:0060306 regulation of membrane repolarization GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity GO:0060401 cytosolic calcium ion transport GO:0060402 calcium ion transport into cytosol GO:0060419 heart growth GO:0060420 regulation of heart growth GO:0060421 positive regulation of heart growth GO:0060537 muscle tissue development GO:0061049 cell growth involved in cardiac muscle cell development GO:0061050 regulation of cell growth involved in cardiac muscle cell development GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development GO:0070296 sarcoplasmic reticulum calcium ion transport GO:0070509 calcium ion import GO:0070588 calcium ion transmembrane transport GO:0070838 divalent metal ion transport GO:0070884 regulation of calcineurin-NFAT signaling cascade GO:0070886 positive regulation of calcineurin-NFAT signaling cascade GO:0071320 cellular response to cAMP GO:0071407 cellular response to organic cyclic compound GO:0071417 cellular response to organonitrogen compound GO:0071804 cellular potassium ion transport GO:0071805 potassium ion transmembrane transport GO:0072503 cellular divalent inorganic cation homeostasis GO:0072507 divalent inorganic cation homeostasis GO:0072511 divalent inorganic cation transport GO:0072522 purine-containing compound biosynthetic process GO:0086009 membrane repolarization GO:0090257 regulation of muscle system process GO:0090279 regulation of calcium ion import GO:0090280 positive regulation of calcium ion import GO:0090316 positive regulation of intracellular protein transport GO:0097553 calcium ion transmembrane import into cytosol GO:0097720 calcineurin-mediated signaling GO:1900180 regulation of protein localization to nucleus GO:1900182 positive regulation of protein localization to nucleus GO:1900371 regulation of purine nucleotide biosynthetic process GO:1900372 negative regulation of purine nucleotide biosynthetic process GO:1900542 regulation of purine nucleotide metabolic process GO:1900543 negative regulation of purine nucleotide metabolic process GO:1901016 regulation of potassium ion transmembrane transporter activity GO:1901018 positive regulation of potassium ion transmembrane transporter activity GO:1901019 regulation of calcium ion transmembrane transporter activity GO:1901021 positive regulation of calcium ion transmembrane transporter activity GO:1901293 nucleoside phosphate biosynthetic process GO:1901379 regulation of potassium ion transmembrane transport GO:1901381 positive regulation of potassium ion transmembrane transport GO:1901861 regulation of muscle tissue development GO:1901863 positive regulation of muscle tissue development GO:1902259 regulation of delayed rectifier potassium channel activity GO:1902261 positive regulation of delayed rectifier potassium channel activity GO:1902593 single-organism nuclear import GO:1902656 calcium ion import into cytosol GO:1903169 regulation of calcium ion transmembrane transport GO:1903514 calcium ion transport from endoplasmic reticulum to cytosol GO:1903533 regulation of protein targeting GO:1903818 positive regulation of voltage-gated potassium channel activity GO:1903829 positive regulation of cellular protein localization GO:1904062 regulation of cation transmembrane transport GO:1904064 positive regulation of cation transmembrane transport GO:1904427 positive regulation of calcium ion transmembrane transport GO:1904589 regulation of protein import GO:1904591 positive regulation of protein import GO:1904951 positive regulation of establishment of protein localization GO:1905207 regulation of cardiocyte differentiation GO:1905209 positive regulation of cardiocyte differentiation GO:2000021 regulation of ion homeostasis GO:2000273 positive regulation of receptor activity GO:2000725 regulation of cardiac muscle cell differentiation GO:2000727 positive regulation of cardiac muscle cell differentiation GO:2001257 regulation of cation channel activity GO:2001259 positive regulation of cation channel activity
Molecular Function	GO:0008179 adenylate cyclase binding GO:0032947 protein complex scaffold GO:0034237 protein kinase A regulatory subunit binding GO:0043495 protein anchor GO:0044325 ion channel binding GO:0051018 protein kinase A binding
Cellular Component	GO:0005635 nuclear envelope GO:0005901 caveola GO:0014701 junctional sarcoplasmic reticulum membrane GO:0014704 intercalated disc GO:0016528 sarcoplasm GO:0016529 sarcoplasmic reticulum GO:0030315 T-tubule GO:0031965 nuclear membrane GO:0033017 sarcoplasmic reticulum membrane GO:0034702 ion channel complex GO:0034703 cation channel complex GO:0034704 calcium channel complex GO:0042383 sarcolemma GO:0044291 cell-cell contact zone GO:0044853 plasma membrane raft GO:0045121 membrane raft GO:0098589 membrane region GO:0098857 membrane microdomain GO:1902495 transmembrane transporter complex GO:1990351 transporter complex

> KEGG and Reactome Pathway [ TOP ]
KEGG	-
Reactome	-

Summary
Symbol	AKAP6
Name	A kinase (PRKA) anchor protein 6
Aliases	KIAA0311; mAKAP; AKAP100; PRKA6; ADAP6; protein kinase A anchoring protein 6; ADAP100; A-kinase anchor prote ......
Chromosomal Location	14q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content	Literatures that report relations between AKAP6 and anti-tumor immunity. The specific mechanism were also collected if the literature reports that a gene specifically promotes or inhibits the infiltration or function of T/NK cells.

> Text Mining [ TOP ]
There is no record.

Summary
Symbol	AKAP6
Name	A kinase (PRKA) anchor protein 6
Aliases	KIAA0311; mAKAP; AKAP100; PRKA6; ADAP6; protein kinase A anchoring protein 6; ADAP100; A-kinase anchor prote ......
Chromosomal Location	14q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content	High-throughput screening data (e.g. CRISPR-Cas9, shRNA and RNAi) for T cell-mediated killing. Genetic screen techniques can identify mechanisms of tumor cell resistance (e.g., PTPN2) and sensitivity (e.g., APLNR) to killing by cytotoxic T cells, the central effectors of anti-tumor immunity. After comprehensively searching, eight groups of screening data sets were collected in the current database. In this tab, users can check whether their selected genes cause resistance or increase sensitivity to T cell-mediated killing in various data sets.

> High-throughput Screening

[ TOP ]

Statistical results of AKAP6 in screening data sets for detecting immune reponses.

PMID	Screening System	Cancer Type	Cell Line	Data Set	Statistical Results	Relation to immunity
29301958	CRISPR-Cas9	melanoma	B16F10	Pmel-1 T cell	NA/NS	NA/NS
29301958	CRISPR-Cas9	melanoma	B16F10	OT-1 T cell	NA/NS	NA/NS
28783722	CRISPR-Cas9	melanoma	Mel624	2CT-CRISPR	NA/NS	NA/NS
28723893	CRISPR-Cas9	melanoma	B16	GVAX+Anti-PD1	NA/NS	NA/NS
28723893	CRISPR-Cas9	melanoma	B16	GVAX	NA/NS	NA/NS
25691366	RNAi	Breast cancer	MCF7	Luc-CTL assay	NA/NS	NA/NS
24476824	shRNA	melanoma	B16	Primary screen	NA/NS	NA/NS
24476824	shRNA	melanoma	B16	Secondary screen	NA/NS	NA/NS

Summary
Symbol	AKAP6
Name	A kinase (PRKA) anchor protein 6
Aliases	KIAA0311; mAKAP; AKAP100; PRKA6; ADAP6; protein kinase A anchoring protein 6; ADAP100; A-kinase anchor prote ......
Chromosomal Location	14q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content	Transcriptomic and genomic profiling of pre-treated tumor biopsies from responders and non-responders to immunotherapy. These data were used to identify signatures and mechanisms of response to checkpoint blockade (e.g., anti-PDL1 and anti-PD1). One example is that mutations in the gene PBRM1 benefit clinical survival of patients with clear cell renal cell carcinoma. After comprehensively searching, we collected 5 and 6 of transcriptomic and genomic data sets, respectively. In this tab, users can check whether their selected genes have significant difference of expression or mutation between responders and non-responders in various data sets. > Expression difference between responders and non-responders > Mutation difference between responders and non-responders

> Expression difference between responders and non-responders

[ TOP ]

Points in the above scatter plot represent the expression difference of AKAP6 in various data sets.

No	PMID	Cancer type	Group	Drug	# Res	# NRes	Log2 (Fold Change)	P value
1	26997480	Melanoma	all	Anti-PD-1 (pembrolizumab and nivolumab)	14	12	0.646	0.294
2	26997480	Melanoma	MAPKi	Anti-PD-1 (pembrolizumab and nivolumab)	6	5	-0.004	0.997
3	26997480	Melanoma	non-MAPKi	Anti-PD-1 (pembrolizumab and nivolumab)	8	7	1.118	0.232
4	28552987	Urothelial cancer	all	Anti-PD-L1 (atezolizumab)	9	16	-0.631	0.254
5	28552987	Urothelial cancer	smoking	Anti-PD-L1 (atezolizumab)	5	9	-0.754	0.702
6	28552987	Urothelial cancer	non-smoking	Anti-PD-L1 (atezolizumab)	4	7	-0.482	0.835
7	29033130	Melanoma	all	Anti-PD-1 (nivolumab)	26	23	0.175	0.812
8	29033130	Melanoma	NIV3-PROG	Anti-PD-1 (nivolumab)	15	11	-1.515	0.343
9	29033130	Melanoma	NIV3-NAIVE	Anti-PD-1 (nivolumab)	11	12	2.174	0.176
10	29301960	Clear cell renal cell carcinoma (ccRCC)	all	Anti-PD-1 (nivolumab)	4	8	0.347	0.625
11	29301960	Clear cell renal cell carcinoma (ccRCC)	VEGFRi	Anti-PD-1 (nivolumab)	2	0	0	1
12	29301960	Clear cell renal cell carcinoma (ccRCC)	non-VEGFRi	Anti-PD-1 (nivolumab)	2	8	1.197	0.178
13	29443960	Urothelial cancer	all	Anti-PD-L1 (atezolizumab)	68	230	-0.216	0.216

> Mutation difference between responders and non-responders

[ TOP ]

Points in the above scatter plot represent the mutation difference of AKAP6 in various data sets.

No	PMID	Cancer type	Group	Drug	# Res	# NRes	% Mut/Res	% Mut/NRes	% Diff (R vs NR)	Pval
1	25765070	Non-small cell lung cancer (NSCLC)	all	Anti-PD-1 (pembrolizumab)	14	17	7.1	11.8	-4.7	1
2	25765070	Non-small cell lung cancer (NSCLC)	smoking	Anti-PD-1 (pembrolizumab)	10	3	10	33.3	-23.3	0.423
3	25765070	Non-small cell lung cancer (NSCLC)	non-smoking	Anti-PD-1 (pembrolizumab)	4	14	0	7.1	-7.1	1
4	26359337	Melanoma	all	Anti-CTLA-4 (ipilimumab)	27	73	14.8	2.7	12.1	0.0439
5	26359337	Melanoma	BRAFi	Anti-CTLA-4 (ipilimumab)	0	14	0	0	0	1
6	26359337	Melanoma	non-BRAFi	Anti-CTLA-4 (ipilimumab)	27	59	14.8	3.4	11.4	0.0746
7	26997480	Melanoma	all	Anti-PD-1 (pembrolizumab and nivolumab)	21	17	4.8	5.9	-1.1	1
8	26997480	Melanoma	MAPKi	Anti-PD-1 (pembrolizumab and nivolumab)	8	6	12.5	0	12.5	1
9	26997480	Melanoma	non-MAPKi	Anti-PD-1 (pembrolizumab and nivolumab)	13	11	0	9.1	-9.1	0.458
10	28552987	Urothelial cancer	all	Anti-PD-L1 (atezolizumab)	9	16	11.1	6.2	4.9	1
11	28552987	Urothelial cancer	smoking	Anti-PD-L1 (atezolizumab)	5	9	0	11.1	-11.1	1
12	28552987	Urothelial cancer	non-smoking	Anti-PD-L1 (atezolizumab)	4	7	25	0	25	0.364
13	29033130	Melanoma	all	Anti-PD-1 (nivolumab)	38	27	13.2	0	13.2	0.0705
14	29033130	Melanoma	NIV3-PROG	Anti-PD-1 (nivolumab)	22	13	9.1	0	9.1	0.519
15	29033130	Melanoma	NIV3-NAIVE	Anti-PD-1 (nivolumab)	16	14	18.8	0	18.8	0.228
16	29301960	Clear cell renal cell carcinoma (ccRCC)	all	Anti-PD-1 (nivolumab)	11	13	0	0	0	1
17	29301960	Clear cell renal cell carcinoma (ccRCC)	VEGFRi	Anti-PD-1 (nivolumab)	6	1	0	0	0	1
18	29301960	Clear cell renal cell carcinoma (ccRCC)	non-VEGFRi	Anti-PD-1 (nivolumab)	5	12	0	0	0	1

Summary
Symbol	AKAP6
Name	A kinase (PRKA) anchor protein 6
Aliases	KIAA0311; mAKAP; AKAP100; PRKA6; ADAP6; protein kinase A anchoring protein 6; ADAP100; A-kinase anchor prote ......
Chromosomal Location	14q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content	Relations between abundance of tumor-infiltrating lymphocytes (TILs) and expression, copy number, methylation, or mutation of AKAP6. The immune-related signatures of 28 TIL types from Charoentong's study, which can be viewed in the download page. For each cancer type, the relative abundance of TILs were inferred by using gene set variation analysis (GSVA) based on gene expression profile. In this tab, users can examine which kinds of TILs might be regulated by the current gene.

> Lymphocyte [ TOP ]

Summary
Symbol	AKAP6
Name	A kinase (PRKA) anchor protein 6
Aliases	KIAA0311; mAKAP; AKAP100; PRKA6; ADAP6; protein kinase A anchoring protein 6; ADAP100; A-kinase anchor prote ......
Chromosomal Location	14q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content	Relations between three kinds of immunomodulators and expression, copy number, methylation, or mutation of AKAP6. These immunomo-dulators were collected from Charoentong's study. In this tab, users can examine which immunomodulators might be regulated by AKAP6. > Immunoinhibitor > Immunostimulator > MHC molecule

> Immunoinhibitor [ TOP ]

> Immunostimulator [ TOP ]

> MHC molecule [ TOP ]

Summary
Symbol	AKAP6
Name	A kinase (PRKA) anchor protein 6
Aliases	KIAA0311; mAKAP; AKAP100; PRKA6; ADAP6; protein kinase A anchoring protein 6; ADAP100; A-kinase anchor prote ......
Chromosomal Location	14q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content	Relations between chemokines (or receptors) and expression, copy number, methylation, or mutation of AKAP6. In this tab, users can examine which chemokines (or receptors) might be regulated by the current gene. > Chemokine > Receptor

> Chemokine [ TOP ]

> Receptor [ TOP ]

Summary
Symbol	AKAP6
Name	A kinase (PRKA) anchor protein 6
Aliases	KIAA0311; mAKAP; AKAP100; PRKA6; ADAP6; protein kinase A anchoring protein 6; ADAP100; A-kinase anchor prote ......
Chromosomal Location	14q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content	Distribution of AKAP6 expression across immune and molecular subtypes. > Immune subtype > Molecular subtype

> Immune subtype [ TOP ]

> Molecular subtype [ TOP ]

Summary
Symbol	AKAP6
Name	A kinase (PRKA) anchor protein 6
Aliases	KIAA0311; mAKAP; AKAP100; PRKA6; ADAP6; protein kinase A anchoring protein 6; ADAP100; A-kinase anchor prote ......
Chromosomal Location	14q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content	Associations between AKAP6 and clinical features. > Overall survival analysis > Cancer stage > Tumor grade

> Overall survival [ TOP ]

> Stage [ TOP ]

> Grade [ TOP ]

Summary
Symbol	AKAP6
Name	A kinase (PRKA) anchor protein 6
Aliases	KIAA0311; mAKAP; AKAP100; PRKA6; ADAP6; protein kinase A anchoring protein 6; ADAP100; A-kinase anchor prote ......
Chromosomal Location	14q12
External Links	HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content	Drugs targeting AKAP6 collected from DrugBank database.

> Drugs from DrugBank database [ TOP ]
There is no record.

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